<?xml version="1.0" encoding="UTF-8"?>
<!-- 
 * #%L
 * org.hl7.fhir.r5
 * %%
 * Copyright (C) 2014 - 2019 Health Level 7
 * %%
 * Licensed under the Apache License, Version 2.0 (the "License");
 * you may not use this file except in compliance with the License.
 * You may obtain a copy of the License at
 * 
 *      http://www.apache.org/licenses/LICENSE-2.0
 * 
 * Unless required by applicable law or agreed to in writing, software
 * distributed under the License is distributed on an "AS IS" BASIS,
 * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 * See the License for the specific language governing permissions and
 * limitations under the License.
 * #L%
 */

/*
  Copyright (c) 2011+, HL7, Inc.
  All rights reserved.
  
  Redistribution and use in source and binary forms, with or without modification, 
  are permitted provided that the following conditions are met:
  
   * Redistributions of source code must retain the above copyright notice, this 
     list of conditions and the following disclaimer.
   * Redistributions in binary form must reproduce the above copyright notice, 
     this list of conditions and the following disclaimer in the documentation 
     and/or other materials provided with the distribution.
   * Neither the name of HL7 nor the names of its contributors may be used to 
     endorse or promote products derived from this software without specific 
     prior written permission.
  
  THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND 
  ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED 
  WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. 
  IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, 
  INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT 
  NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR 
  PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, 
  WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) 
  ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE 
  POSSIBILITY OF SUCH DAMAGE.
  

  Generated on Thu, Apr 9, 2026 17:12+0000 for FHIR v6.0.0-ballot4 

  Note: the schemas &amp; schematrons do not contain all of the rules about what makes resources
  valid. Implementers will still need to be familiar with the content of the specification and with
  any profiles that apply to the resources in order to make a conformant implementation.

-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns="http://hl7.org/fhir" xmlns:xhtml="http://www.w3.org/1999/xhtml" targetNamespace="http://hl7.org/fhir" elementFormDefault="qualified" version="1.0">
  <xs:include schemaLocation="fhir-base.xsd"/>
  <xs:element name="ManufacturedItemDefinition" type="ManufacturedItemDefinition">
    <xs:annotation>
      <xs:documentation xml:lang="en">The definition and characteristics of a medicinal manufactured item, such as a tablet or capsule, as contained in a packaged medicinal product.</xs:documentation>
    </xs:annotation>
  </xs:element>
  <xs:complexType name="ManufacturedItemDefinition">
    <xs:annotation>
      <xs:documentation xml:lang="en">The definition and characteristics of a medicinal manufactured item, such as a tablet or capsule, as contained in a packaged medicinal product.</xs:documentation>
      <xs:documentation xml:lang="en">If the element is present, it must have either a @value, an @id, or extensions</xs:documentation>
    </xs:annotation>
    <xs:complexContent>
      <xs:extension base="DomainResource">
        <xs:sequence>
          <xs:element name="identifier" minOccurs="0" maxOccurs="unbounded" type="Identifier">
            <xs:annotation>
              <xs:documentation xml:lang="en">Unique identifier.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="status" minOccurs="1" maxOccurs="1" type="PublicationStatus">
            <xs:annotation>
              <xs:documentation xml:lang="en">The status of this item. Enables tracking the life-cycle of the content.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="name" minOccurs="0" maxOccurs="1" type="string">
            <xs:annotation>
              <xs:documentation xml:lang="en">A descriptive name applied to this item.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="manufacturedDoseForm" minOccurs="1" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">Dose form as manufactured and before any transformation into the pharmaceutical product.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="unitOfPresentation" minOccurs="0" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The “real-world” units in which the quantity of the manufactured item is described.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="manufacturer" minOccurs="0" maxOccurs="unbounded" type="Reference">
            <xs:annotation>
              <xs:documentation xml:lang="en">Manufacturer of the item, one of several possible.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="marketingStatus" minOccurs="0" maxOccurs="unbounded" type="MarketingStatus">
            <xs:annotation>
              <xs:documentation xml:lang="en">Allows specifying that an item is on the market for sale, or that it is not available, and the dates and locations associated.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="ingredient" minOccurs="0" maxOccurs="unbounded" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The ingredients of this manufactured item. This is only needed if the ingredients are not specified by incoming references from the Ingredient resource.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="property" type="ManufacturedItemDefinition.Property" minOccurs="0" maxOccurs="unbounded">
            <xs:annotation>
              <xs:documentation xml:lang="en">General characteristics of this item.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="component" type="ManufacturedItemDefinition.Component" minOccurs="0" maxOccurs="unbounded">
            <xs:annotation>
              <xs:documentation xml:lang="en">Physical parts of the manufactured item, that it is intrinsically made from. This is distinct from the ingredients that are part of its chemical makeup.</xs:documentation>
           </xs:annotation>
          </xs:element>
        </xs:sequence>
      </xs:extension>
    </xs:complexContent>
  </xs:complexType>
  <xs:complexType name="ManufacturedItemDefinition.Property">
    <xs:annotation>
      <xs:documentation xml:lang="en">The definition and characteristics of a medicinal manufactured item, such as a tablet or capsule, as contained in a packaged medicinal product.</xs:documentation>
    </xs:annotation>
    <xs:complexContent>
      <xs:extension base="BackboneElement">
        <xs:sequence>
          <xs:element name="type" minOccurs="1" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">A code expressing the type of characteristic.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:choice minOccurs="0" maxOccurs="1" >
            <xs:annotation>
              <xs:documentation xml:lang="en">A value for the characteristic.</xs:documentation>
            </xs:annotation>
            <xs:element name="valueCodeableConcept" type="CodeableConcept"/>
            <xs:element name="valueQuantity" type="Quantity"/>
            <xs:element name="valueRange" type="Range"/>
            <xs:element name="valueDate" type="date"/>
            <xs:element name="valueBoolean" type="boolean"/>
            <xs:element name="valueMarkdown" type="markdown"/>
            <xs:element name="valueAttachment" type="Attachment"/>
            <xs:element name="valueReference" type="Reference"/>
          </xs:choice>
        </xs:sequence>
      </xs:extension>
    </xs:complexContent>
  </xs:complexType>
  <xs:complexType name="ManufacturedItemDefinition.Component">
    <xs:annotation>
      <xs:documentation xml:lang="en">The definition and characteristics of a medicinal manufactured item, such as a tablet or capsule, as contained in a packaged medicinal product.</xs:documentation>
    </xs:annotation>
    <xs:complexContent>
      <xs:extension base="BackboneElement">
        <xs:sequence>
          <xs:element name="type" minOccurs="1" maxOccurs="1" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">Defining type of the component e.g. shell, layer, ink.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="function" minOccurs="0" maxOccurs="unbounded" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The function of this component within the item e.g. delivers active ingredient, masks taste.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="amount" minOccurs="0" maxOccurs="unbounded" type="Quantity">
            <xs:annotation>
              <xs:documentation xml:lang="en">The measurable amount of total quantity of all substances in the component, expressible in different ways (e.g. by mass or volume).</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="constituent" type="ManufacturedItemDefinition.Constituent" minOccurs="0" maxOccurs="unbounded">
            <xs:annotation>
              <xs:documentation xml:lang="en">A reference to a constituent of the manufactured item as a whole, linked here so that its component location within the item can be indicated. This not where the item's ingredient are primarily stated (for which see Ingredient.for or ManufacturedItemDefinition.ingredient).</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="property" type="ManufacturedItemDefinition.Property" minOccurs="0" maxOccurs="unbounded">
            <xs:annotation>
              <xs:documentation xml:lang="en">General characteristics of this component.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="component" type="ManufacturedItemDefinition.Component" minOccurs="0" maxOccurs="unbounded">
            <xs:annotation>
              <xs:documentation xml:lang="en">A component that this component contains or is made from.</xs:documentation>
           </xs:annotation>
          </xs:element>
        </xs:sequence>
      </xs:extension>
    </xs:complexContent>
  </xs:complexType>
  <xs:complexType name="ManufacturedItemDefinition.Constituent">
    <xs:annotation>
      <xs:documentation xml:lang="en">The definition and characteristics of a medicinal manufactured item, such as a tablet or capsule, as contained in a packaged medicinal product.</xs:documentation>
    </xs:annotation>
    <xs:complexContent>
      <xs:extension base="BackboneElement">
        <xs:sequence>
          <xs:element name="amount" minOccurs="0" maxOccurs="unbounded" type="Quantity">
            <xs:annotation>
              <xs:documentation xml:lang="en">The measurable amount of the substance, expressible in different ways (e.g. by mass or volume).</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="location" minOccurs="0" maxOccurs="unbounded" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The physical location of the constituent/ingredient within the component. Example – if the component is the bead in the capsule, then the location would be where the ingredient resides within the product part – intragranular, extra-granular, etc.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="function" minOccurs="0" maxOccurs="unbounded" type="CodeableConcept">
            <xs:annotation>
              <xs:documentation xml:lang="en">The function of this constituent within the component e.g. binder.</xs:documentation>
           </xs:annotation>
          </xs:element>
          <xs:element name="hasIngredient" minOccurs="0" maxOccurs="unbounded" type="CodeableReference">
            <xs:annotation>
              <xs:documentation xml:lang="en">The ingredient that is the constituent of the given component.</xs:documentation>
           </xs:annotation>
          </xs:element>
        </xs:sequence>
      </xs:extension>
    </xs:complexContent>
  </xs:complexType>
</xs:schema>
