<?xml version="1.0" encoding="UTF-8"?><MedicationRequest xmlns="http://hl7.org/fhir">
  <id value="medrx0317"/>
  <meta>
    <security>
      <system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/>
      <code value="HTEST"/>
      <display value="test health data"/>
    </security>
  </meta>
  <contained>
    <Medication>
      <id value="med0303"/>
      <code>
        <coding>
          <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
          <code value="1594660"/>
          <display value="alemtuzumab 10 MG/ML [Lemtrada]"/>
        </coding>
      </code>
    </Medication>
  </contained>
  <identifier>
    <use value="official"/>
    <system value="http://www.bmc.nl/portal/prescriptions"/>
    <value value="12345689"/>
  </identifier>
  <status value="completed"/>
  <intent value="order"/>
  <medication>
    <reference>
      <reference value="#med0303"/>
    </reference>
  </medication>
  <subject>
    <!-- Linked to the resource patient who needs the medication -->
    <reference value="Patient/pat1"/>
    <display value="Donald Duck"/>
  </subject>
  <authoredOn value="2015-01-15"/>
  <requester>
    <reference value="Practitioner/f007"/>
    <display value="Patrick Pump"/>
  </requester>
  <reason>
    <concept>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="92814006"/>
        <display value="Chronic lymphoid leukemia, disease (disorder)"/>
      </coding>
    </concept>
  </reason>
  <dosageInstruction>
    <renderedInstruction value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, then 10 mg/d, to 30 mg IV over 120 min, 3 times per week on alternate days for up to 12 weeks."/>
    <step>
      <component>
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/>
        <additionalInstruction>
          <text value="Rapidly increase dose until tolerated"/>
        </additionalInstruction>
        <additionalInstruction>
          <text value="Administer on alternate days"/>
        </additionalInstruction>
        <timing>
          <repeat>
            <duration value="12"/>
            <durationUnit value="wk"/>
            <frequency value="3"/>
            <period value="1"/>
            <periodUnit value="wk"/>
          </repeat>
        </timing>
        <route>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="47625008"/>
            <display value="Intravenous route"/>
          </coding>
        </route>
        <method>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="422145002"/>
            <display value="Inject - dosing instruction imperative (qualifier value)"/>
          </coding>
        </method>
        <doseAndRate>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>
              <code value="ordered"/>
              <display value="Ordered"/>
            </coding>
          </type>
          <doseQuantity>
            <value value="3"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
          </doseQuantity>
        </doseAndRate>
      </component>
    </step>
    <step>
      <component>
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/>
        <additionalInstruction>
          <text value="Rapidly increase dose until tolerated"/>
        </additionalInstruction>
        <additionalInstruction>
          <text value="Administer on alternate days"/>
        </additionalInstruction>
        <timing>
          <repeat>
            <duration value="12"/>
            <durationUnit value="wk"/>
            <frequency value="3"/>
            <period value="1"/>
            <periodUnit value="wk"/>
          </repeat>
        </timing>
        <route>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="47625008"/>
            <display value="Intravenous route"/>
          </coding>
        </route>
        <method>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="422145002"/>
            <display value="Inject - dosing instruction imperative (qualifier value)"/>
          </coding>
        </method>
        <doseAndRate>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>
              <code value="ordered"/>
              <display value="Ordered"/>
            </coding>
          </type>
          <doseQuantity>
            <value value="10"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
          </doseQuantity>
        </doseAndRate>
      </component>
    </step>
    <step>
      <component>
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/>
        <additionalInstruction>
          <text value="Rapidly increase dose until tolerated"/>
        </additionalInstruction>
        <additionalInstruction>
          <text value="Administer on alternate days"/>
        </additionalInstruction>
        <timing>
          <repeat>
            <duration value="12"/>
            <durationUnit value="wk"/>
            <frequency value="3"/>
            <period value="1"/>
            <periodUnit value="wk"/>
          </repeat>
        </timing>
        <route>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="47625008"/>
            <display value="Intravenous route"/>
          </coding>
        </route>
        <method>
          <coding>
            <system value="http://snomed.info/sct"/>
            <code value="422145002"/>
            <display value="Inject - dosing instruction imperative (qualifier value)"/>
          </coding>
        </method>
        <doseAndRate>
          <type>
            <coding>
              <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>
              <code value="ordered"/>
              <display value="Ordered"/>
            </coding>
          </type>
          <doseQuantity>
            <value value="30"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
          </doseQuantity>
        </doseAndRate>
      </component>
    </step>
  </dosageInstruction>
</MedicationRequest>