<?xml version="1.0" encoding="UTF-8"?>

  <!-- Example: Dermatophagoides farinae allergen — a structurally diverse
     substance (an allergen derived from a house dust mite). From ISO 11238 IG
     examples. Demonstrates SubstanceDefinition for a structurally-diverse
     substance: classification, sourceMaterial (taxonomy), no chemical
     structure or sequence. -->
<SubstanceDefinition xmlns="http://hl7.org/fhir">
  <id value="dermatophagoides-farinae"/>
  <identifier>
    <system value="http://example.europa.eu/fhir/SMSId"/>
    <value value="DERMFAR1S"/>
  </identifier>
  <status>
    <coding>
      <system value="http://hl7.org/fhir/publication-status"/>
      <code value="active"/>
      <display value="Active"/>
    </coding>
  </status>
  <classification>
    <coding>
      <system value="http://example.europa.eu/fhir/SubstanceType"/>
      <code value="structurally-diverse"/>
      <display value="Structurally Diverse"/>
    </coding>
  </classification>
  <domain>
    <coding>
      <system value="http://example.europa.eu/fhir/Domain"/>
      <code value="human"/>
      <display value="Human use"/>
    </coding>
  </domain>
  <description value="Dermatophagoides farinae — American house dust mite allergen extract. A structurally diverse substance defined by its source organism rather than a discrete chemical structure, used in allergen immunotherapy products."/>
  <code>
    <code>
      <coding>
        <system value="http://example.europa.eu/fhir/Substance"/>
        <code value="DERMFAR1S"/>
      </coding>
    </code>
  </code>
  <name>
    <name value="Dermatophagoides farinae"/>
    <preferred value="true"/>
    <language>
      <coding>
        <system value="urn:ietf:bcp:47"/>
        <code value="en"/>
        <display value="English"/>
      </coding>
    </language>
    <official>
      <authority>
        <coding>
          <system value="http://hl7.org/fhir/substance-name-authority"/>
          <code value="USAN"/>
          <display value="USAN"/>
        </coding>
      </authority>
      <status>
        <coding>
          <system value="http://hl7.org/fhir/publication-status"/>
          <code value="active"/>
          <display value="Active"/>
        </coding>
      </status>
    </official>
  </name>
  <name>
    <name value="American house dust mite"/>
    <preferred value="false"/>
  </name>
  <sourceMaterial>
    <type>
      <coding>
        <system value="http://hl7.org/fhir/substance-source-material-type"/>
        <code value="Animal"/>
        <display value="Animal"/>
      </coding>
    </type>
    <genus>
      <coding>
        <system value="http://example.europa.eu/fhir/Genus"/>
        <code value="Dermatophagoides"/>
        <display value="Dermatophagoides"/>
      </coding>
    </genus>
    <species>
      <coding>
        <system value="http://example.europa.eu/fhir/Species"/>
        <code value="farinae"/>
        <display value="D. farinae"/>
      </coding>
    </species>
    <part>
      <coding>
        <system value="http://example.europa.eu/fhir/Part"/>
        <code value="whole-organism"/>
        <display value="Whole organism"/>
      </coding>
    </part>
  </sourceMaterial>
</SubstanceDefinition>