<?xml version="1.0" encoding="UTF-8"?><ClinicalUseDefinition xmlns="http://hl7.org/fhir">
  <id value="example-interaction"/>
  <meta>
    <security>
      <system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/>
      <code value="HTEST"/>
      <display value="test health data"/>
    </security>
  </meta>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="brr"/>
  </extension>
  <!--  example product interacts with other drugs  -->
  <type value="interaction"/>
  <subject>
    <reference>
      <reference value="MedicinalProductDefinition/example"/>
    </reference>
  </subject>
  <interaction>
    <interactant>
      <itemCodeableConcept>
        <coding>
          <system value="http://ema.europa.eu/example/interactant"/>
          <code value="alphaconazole"/>
        </coding>
      </itemCodeableConcept>
    </interactant>
    <interactant>
      <itemCodeableConcept>
        <coding>
          <system value="http://ema.europa.eu/example/interactant"/>
          <code value="betaconazole"/>
        </coding>
      </itemCodeableConcept>
    </interactant>
    <type>
      <coding>
        <system value="http://ema.europa.eu/example/interactionsType"/>
        <code value="Inhibitor"/>
      </coding>
    </type>
    <effect>
      <concept>
        <text value="Increased plasma concentration"/>
      </concept>
    </effect>
    <management>
      <text value="Careful monitoring of dose"/>
    </management>
  </interaction>
</ClinicalUseDefinition>