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Ingredient.shex

Biomedical Research and Regulation Work GroupMaturity Level: N/AStandards Status: InformativeCompartments: No defined compartments

Raw ShEx

ShEx statement for ingredient

PREFIX fhir: <http://hl7.org/fhir/> 
PREFIX fhirvs: <http://hl7.org/fhir/ValueSet/>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#> 
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> 

IMPORT <code.shex>
IMPORT <Ratio.shex>
IMPORT <string.shex>
IMPORT <boolean.shex>
IMPORT <markdown.shex>
IMPORT <Quantity.shex>
IMPORT <Reference.shex>
IMPORT <Identifier.shex>
IMPORT <RatioRange.shex>
IMPORT <Organization.shex>
IMPORT <DomainResource.shex>
IMPORT <CodeableConcept.shex>
IMPORT <BackboneElement.shex>
IMPORT <CodeableReference.shex>
IMPORT <ManufacturedItemDefinition.shex>
IMPORT <MedicinalProductDefinition.shex>
IMPORT <AdministrableProductDefinition.shex>


start=@<Ingredient> AND {fhir:nodeRole [fhir:treeRoot]}

# An ingredient of a manufactured item or pharmaceutical product
<Ingredient> EXTENDS @<DomainResource> CLOSED {   

    a [fhir:Ingredient]?;
    fhir:nodeRole [fhir:treeRoot]?;

    fhir:identifier @<Identifier>?;         # An identifier or code by which the 
                                            # ingredient can be referenced 
    fhir:status @<code> AND
    	{fhir:v @fhirvs:publication-status};  # draft | active | retired | unknown
    fhir:for @<OneOrMore_Reference_AdministrableProductDefinition_OR_ManufacturedItemDefinition_OR_MedicinalProductDefinition>?;  # The product which this ingredient 
                                            # is a constituent part of 
    fhir:role @<CodeableConcept>;           # Purpose of the ingredient within 
                                            # the product, e.g. active, inactive 
    fhir:function @<OneOrMore_CodeableConcept>?;  # Precise action within the drug 
                                            # product, e.g. antioxidant, 
                                            # alkalizing agent 
    fhir:group @<CodeableConcept>?;         # A classification of the ingredient 
                                            # according to where in the physical 
                                            # item it tends to be used, such the 
                                            # outer shell of a tablet, inner 
                                            # body or ink 
    fhir:allergenicIndicator @<boolean>?;   # If the ingredient is a known or 
                                            # suspected allergen 
    fhir:comment @<markdown>?;              # A place for providing any notes 
                                            # that are relevant to the 
                                            # component, e.g. removed during 
                                            # process, adjusted for loss on 
                                            # drying 
    fhir:manufacturer @<OneOrMore_Ingredient.manufacturer>?;  # An organization that manufactures 
                                            # this ingredient 
    fhir:substance @<Ingredient.substance>;  # The substance that comprises this 
                                            # ingredient 
}  

# The quantity of substance, per presentation, or per volume or mass, and type of quantity
<Ingredient.substance.strength> EXTENDS @<BackboneElement> CLOSED {   
    fhir:presentation @<Ratio>  OR 
    			@<RatioRange>  OR 
    			@<CodeableConcept>  OR 
    			@<Quantity>  ?;  # The quantity of substance in the 
                                            # unit of presentation 
    fhir:textPresentation @<string>?;       # Text of either the whole 
                                            # presentation strength or a part of 
                                            # it (rest being in 
                                            # Strength.presentation as a ratio) 
    fhir:concentration @<Ratio>  OR 
    			@<RatioRange>  OR 
    			@<CodeableConcept>  OR 
    			@<Quantity>  ?;  # The strength per unitary volume 
                                            # (or mass) 
    fhir:textConcentration @<string>?;      # Text of either the whole 
                                            # concentration strength or a part 
                                            # of it (rest being in 
                                            # Strength.concentration as a ratio) 
    fhir:basis @<CodeableConcept>?;         # A code that indicates if the 
                                            # strength is, for example, based on 
                                            # the ingredient substance as stated 
                                            # or on the substance base (when the 
                                            # ingredient is a salt) 
    fhir:measurementPoint @<string>?;       # When strength is measured at a 
                                            # particular point or distance 
    fhir:country @<OneOrMore_CodeableConcept>?;  # Where the strength range applies
    fhir:referenceStrength @<OneOrMore_Ingredient.substance.strength.referenceStrength>?;  # Strength expressed in terms of a 
                                            # reference substance 
}  

# The substance that comprises this ingredient
<Ingredient.substance> EXTENDS @<BackboneElement> CLOSED {   
    fhir:code @<CodeableReference>;         # A code or full resource that 
                                            # represents the ingredient 
                                            # substance 
    fhir:strength @<OneOrMore_Ingredient.substance.strength>?;  # The quantity of substance, per 
                                            # presentation, or per volume or 
                                            # mass, and type of quantity 
}  

# Strength expressed in terms of a reference substance
<Ingredient.substance.strength.referenceStrength> EXTENDS @<BackboneElement> CLOSED {   
    fhir:substance @<CodeableReference>;    # Relevant reference substance
    fhir:strength @<Ratio>  OR 
    			@<RatioRange>  OR 
    			@<Quantity>  ;  # Strength expressed in terms of a 
                                            # reference substance 
    fhir:measurementPoint @<string>?;       # When strength is measured at a 
                                            # particular point or distance 
    fhir:country @<OneOrMore_CodeableConcept>?;  # Where the strength range applies
}  

# An organization that manufactures this ingredient
<Ingredient.manufacturer> EXTENDS @<BackboneElement> CLOSED {   
    fhir:role @<code> AND
    	{fhir:v @fhirvs:ingredient-manufacturer-role}?;  # allowed | possible | actual
    fhir:manufacturer @<Reference> AND {fhir:link 
    			@<Organization> ? };  # An organization that manufactures 
                                            # this ingredient 
}  

#---------------------- Cardinality Types (OneOrMore) -------------------

<OneOrMore_Reference_AdministrableProductDefinition_OR_ManufacturedItemDefinition_OR_MedicinalProductDefinition> CLOSED {
    rdf:first @<Reference> AND {fhir:link 
			@<AdministrableProductDefinition> OR 
			@<ManufacturedItemDefinition> OR 
			@<MedicinalProductDefinition> } ;
    rdf:rest [rdf:nil] OR @<OneOrMore_Reference_AdministrableProductDefinition_OR_ManufacturedItemDefinition_OR_MedicinalProductDefinition> 
}

<OneOrMore_CodeableConcept> CLOSED {
    rdf:first @<CodeableConcept>  ;
    rdf:rest [rdf:nil] OR @<OneOrMore_CodeableConcept> 
}

<OneOrMore_Ingredient.manufacturer> CLOSED {
    rdf:first @<Ingredient.manufacturer>  ;
    rdf:rest [rdf:nil] OR @<OneOrMore_Ingredient.manufacturer> 
}

<OneOrMore_Ingredient.substance.strength.referenceStrength> CLOSED {
    rdf:first @<Ingredient.substance.strength.referenceStrength>  ;
    rdf:rest [rdf:nil] OR @<OneOrMore_Ingredient.substance.strength.referenceStrength> 
}

<OneOrMore_Ingredient.substance.strength> CLOSED {
    rdf:first @<Ingredient.substance.strength>  ;
    rdf:rest [rdf:nil] OR @<OneOrMore_Ingredient.substance.strength> 
}

#---------------------- Value Sets ------------------------

# The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role.
fhirvs:ingredient-manufacturer-role ["allowed" "possible" "actual"]

# The lifecycle status of an artifact.
fhirvs:publication-status ["draft" "active" "retired" "unknown"]


Usage note: every effort has been made to ensure that the ShEx files are correct and useful, but they are not a normative part of the specification.