2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1
2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1
2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide, published by CDC / Security Risk Solutions, Inc. (SRS). This guide is not an authorized publication; it is the continuous build for version 2022.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/security-rs/opioid-cds-r4/ and changes regularly. See the Directory of published versions
| Active as of 2025-02-24 |
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- <http://hl7.org/fhir/ValueSet/naloxone-medications> a fhir:ValueSet ; fhir:nodeRole fhir:treeRoot ; fhir:Resource.id [ fhir:value "naloxone-medications"] ; fhir:Resource.meta [ fhir:Meta.profile [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-computablevalueset" ; fhir:index 0 ; fhir:link <http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-computablevalueset> ], [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-executablevalueset" ; fhir:index 1 ; fhir:link <http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-executablevalueset> ] ] ; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ] ; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet naloxone-medications</b></p><a name=\"naloxone-medications\"> </a><a name=\"hcnaloxone-medications\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profiles: <a href=\"http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-computablevalueset.html\">CPGComputableValueSet</a>, <a href=\"http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-executablevalueset.html\">CPGExecutableValueSet</a></p></div><p style=\"border: black 1px dotted; background-color: #EEEEEE; padding: 8px; margin-bottom: 8px\">Expansion based on codesystem RxNorm version 03022026</p><p>This value set contains 50 concepts</p><table class=\"codes\"><tr><td><b>System</b></td><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1010603\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1010603</td><td>buprenorphine 2 MG / naloxone 0.5 MG Sublingual Film [Suboxone]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1010606\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1010606</td><td>buprenorphine 8 MG / naloxone 2 MG Sublingual Film [Suboxone]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1307058\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1307058</td><td>buprenorphine 4 MG / naloxone 1 MG Sublingual Film [Suboxone]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1307063\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1307063</td><td>buprenorphine 12 MG / naloxone 3 MG Sublingual Film [Suboxone]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1431083\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1431083</td><td>buprenorphine 1.4 MG / naloxone 0.36 MG Sublingual Tablet [Zubsolv]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1431104\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1431104</td><td>buprenorphine 5.7 MG / naloxone 1.4 MG Sublingual Tablet [Zubsolv]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1542396\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1542396</td><td>buprenorphine 2.1 MG / naloxone 0.3 MG Buccal Film [Bunavail]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1544853\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1544853</td><td>buprenorphine 4.2 MG / naloxone 0.7 MG Buccal Film [Bunavail]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1544856\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1544856</td><td>buprenorphine 6.3 MG / naloxone 1 MG Buccal Film [Bunavail]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1597570\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1597570</td><td>buprenorphine 11.4 MG / naloxone 2.9 MG Sublingual Tablet [Zubsolv]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1597575\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1597575</td><td>buprenorphine 8.6 MG / naloxone 2.1 MG Sublingual Tablet [Zubsolv]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1666385\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1666385</td><td>buprenorphine 2.9 MG / naloxone 0.71 MG Sublingual Tablet [Zubsolv]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1725064\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1725064</td><td>naloxone hydrochloride 40 MG/ML Nasal Spray [Narcan]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1864414\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1864414</td><td>buprenorphine 0.7 MG / naloxone 0.18 MG Sublingual Tablet [Zubsolv]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1870935\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1870935</td><td>naloxone hydrochloride 20 MG/ML Nasal Spray [Narcan]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2540709\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2540709</td><td>naloxone hydrochloride 80 MG/ML Nasal Spray [Kloxxado]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2589618\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2589618</td><td>0.5 ML naloxone hydrochloride 10 MG/ML Prefilled Syringe [Zimhi]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2680741\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2680741</td><td>naloxone hydrochloride 16 MG/ML Nasal Spray [Rextovy]</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1010600\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1010600</td><td>buprenorphine 2 MG / naloxone 0.5 MG Sublingual Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1010604\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1010604</td><td>buprenorphine 8 MG / naloxone 2 MG Sublingual Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1191212\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1191212</td><td>naloxone hydrochloride 0.02 MG/ML Injectable Solution</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1191222\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1191222</td><td>naloxone hydrochloride 0.4 MG/ML Injectable Solution</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1191228\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1191228</td><td>naloxone hydrochloride 1 MG/ML Injectable Solution</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1191234\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1191234</td><td>1 ML naloxone hydrochloride 0.4 MG/ML Cartridge</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1191250\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1191250</td><td>2 ML naloxone hydrochloride 1 MG/ML Prefilled Syringe</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1307056\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1307056</td><td>buprenorphine 4 MG / naloxone 1 MG Sublingual Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1307061\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1307061</td><td>buprenorphine 12 MG / naloxone 3 MG Sublingual Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1431076\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1431076</td><td>buprenorphine 1.4 MG / naloxone 0.36 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1431102\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1431102</td><td>buprenorphine 5.7 MG / naloxone 1.4 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1542390\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1542390</td><td>buprenorphine 2.1 MG / naloxone 0.3 MG Buccal Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1544851\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1544851</td><td>buprenorphine 4.2 MG / naloxone 0.7 MG Buccal Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1544854\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1544854</td><td>buprenorphine 6.3 MG / naloxone 1 MG Buccal Film</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1597568\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1597568</td><td>buprenorphine 11.4 MG / naloxone 2.9 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1597573\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1597573</td><td>buprenorphine 8.6 MG / naloxone 2.1 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1659929\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1659929</td><td>1 ML naloxone hydrochloride 0.4 MG/ML Injection</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1666338\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1666338</td><td>buprenorphine 2.9 MG / naloxone 0.71 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1725059\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1725059</td><td>naloxone hydrochloride 40 MG/ML Nasal Spray</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1855730\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1855730</td><td>0.4 ML naloxone hydrochloride 5 MG/ML Auto-Injector</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1864412\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1864412</td><td>buprenorphine 0.7 MG / naloxone 0.18 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1870933\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 1870933</td><td>naloxone hydrochloride 20 MG/ML Nasal Spray</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2540703\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2540703</td><td>naloxone hydrochloride 80 MG/ML Nasal Spray</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2589612\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2589612</td><td>0.5 ML naloxone hydrochloride 10 MG/ML Prefilled Syringe</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2596175\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2596175</td><td>0.4 ML naloxone hydrochloride 25 MG/ML Auto-Injector</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2637879\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2637879</td><td>naloxone hydrochloride 16 MG/ML Nasal Spray</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2673091\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2673091</td><td>naloxone hydrochloride 30 MG/ML Nasal Spray</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2679504\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2679504</td><td>1 ML naloxone hydrochloride 0.4 MG/ML Prefilled Syringe</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2685612\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 2685612</td><td>naloxone hydrochloride 100 MG/ML Nasal Spray</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-312289\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 312289</td><td>naloxone 0.5 MG / pentazocine 50 MG Oral Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-351266\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 351266</td><td>buprenorphine 2 MG / naloxone 0.5 MG Sublingual Tablet</td></tr><tr><td><a name=\"naloxone-medications-http://www.nlm.nih.gov/research/umls/rxnorm-351267\"> </a><code>http://www.nlm.nih.gov/research/umls/rxnorm</code></td><td style=\"white-space:nowrap\"> 351267</td><td>buprenorphine 8 MG / naloxone 2 MG Sublingual Tablet</td></tr></table></div>" ] ; fhir:DomainResource.extension [ fhir:index 0 ; fhir:Extension.url [ fhir:value "http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-clinical-focus" ] ; fhir:Extension.valueString [ fhir:value "All naloxone medications" ] ], [ fhir:index 1 ; fhir:Extension.url [ fhir:value "http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-dataelement-scope" ] ; fhir:Extension.valueString [ fhir:value "Medication" ] ], [ fhir:index 2 ; fhir:Extension.url [ fhir:value "http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-inclusion-criteria" ] ; fhir:Extension.valueString [ fhir:value "All naloxone medications" ] ], [ fhir:index 3 ; fhir:Extension.url [ fhir:value "http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-exclusion-criteria" ] ; fhir:Extension.valueString [ fhir:value "None" ] ], [ fhir:index 4 ; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/valueset-author" ] ; fhir:Extension.valueContactDetail [ fhir:ContactDetail.name [ fhir:value "MD Partners, Inc." ] ; fhir:ContactDetail.telecom [ fhir:index 0 ; fhir:ContactPoint.system [ fhir:value "email" ] ; fhir:ContactPoint.value [ fhir:value "info@mdpartners.com" ] ] ] ], [ fhir:index 5 ; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability" ] ; fhir:Extension.valueCode [ fhir:value "computable" ] ], [ fhir:index 6 ; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability" ] ; fhir:Extension.valueCode [ fhir:value "executable" ] ], [ fhir:index 7 ; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-usageWarning" ] ; fhir:Extension.valueString [ fhir:value "This value set contains a point-in-time expansion enumerating the codes that meet the value set intent. As new versions of the code systems used by the value set are released, the contents of this expansion will need to be updated to incorporate newly defined codes that meet the value set intent. Before, and periodically during production use, the value set expansion contents SHOULD be updated. The value set expansion specifies the timestamp when the expansion was produced, SHOULD contain the parameters used for the expansion, and SHALL contain the codes that are obtained by evaluating the value set definition. If this is ONLY an executable value set, a distributable definition of the value set must be obtained to compute the updated expansion." ] ], [ fhir:index 8 ; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/valueset-rules-text" ] ; fhir:Extension.valueMarkdown [ fhir:value "https://mor.nlm.nih.gov/RxMix/ \r\nScript:\r\nStep 1 \r\nCreate Batch text input file (Naloxone.txt) with following RxNorm identifier for the ingredient (TTY=IN) as the only concept within the file: \r\n7242 \r\n\r\nStep 2\r\nSubmit batch job using the above Naloxone.txt as the input file to following workflow by uploading a workflow file (naloxone-wf.config) with the following text in the file: <WFE><filteredOutputs>RXCUI|name|term_type</filteredOutputs><input>NOINPUT</input><FS><service>NOINPUT</service><function>getRelatedByType</function><level>0</level><paramSize>2</paramSize><param order ='0'>?</param><param order ='1'>BPCK,GPCK,SBD,SCD</param></FS></WFE>" ] ] ; fhir:ValueSet.url [ fhir:value "http://fhir.org/guides/cdc/opioid-cds/ValueSet/naloxone-medications"] ; fhir:ValueSet.identifier [ fhir:index 0 ; fhir:Identifier.system [ fhir:value "urn:ietf:rfc:3986" ] ; fhir:Identifier.value [ fhir:value "urn:oid:2.16.840.1.114222.48.22" ] ] ; fhir:ValueSet.version [ fhir:value "2022.1.1"] ; fhir:ValueSet.name [ fhir:value "NALOXONE_MEDICATIONS"] ; fhir:ValueSet.title [ fhir:value "Naloxone medications"] ; fhir:ValueSet.status [ fhir:value "active"] ; fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean] ; fhir:ValueSet.date [ fhir:value "2025-02-24T13:06:52-07:00"^^xsd:dateTime] ; fhir:ValueSet.publisher [ fhir:value "CDC / Security Risk Solutions, Inc. (SRS)"] ; fhir:ValueSet.contact [ fhir:index 0 ; fhir:ContactDetail.telecom [ fhir:index 0 ; fhir:ContactPoint.system [ fhir:value "url" ] ; fhir:ContactPoint.value [ fhir:value "https://www.securityrisksolutions.com" ] ] ] ; fhir:ValueSet.description [ fhir:value "All naloxone medications"] ; fhir:ValueSet.purpose [ fhir:value "Naloxone medications for opioid management"] ; fhir:ValueSet.copyright [ fhir:value "© CDC 2016+."] ; fhir:ValueSet.expansion [ fhir:ValueSet.expansion.identifier [ fhir:value "urn:uuid:a5098879-ecf1-4442-80ae-566ae6587591" ] ; fhir:ValueSet.expansion.timestamp [ fhir:value "2025-02-24T13:06:52-07:00"^^xsd:dateTime ] ; fhir:ValueSet.expansion.total [ fhir:value "50"^^xsd:integer ] ; fhir:ValueSet.expansion.parameter [ fhir:index 0 ; fhir:ValueSet.expansion.parameter.name [ fhir:value "used-codesystem" ] ; fhir:ValueSet.expansion.parameter.valueUri [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm|03022026" ] ], [ fhir:index 1 ; fhir:ValueSet.expansion.parameter.name [ fhir:value "version" ] ; fhir:ValueSet.expansion.parameter.valueUri [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm|03022026" ] ] ; fhir:ValueSet.expansion.contains [ fhir:index 0 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1010603" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2 MG / naloxone 0.5 MG Sublingual Film [Suboxone]" ] ], [ fhir:index 1 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1010606" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 8 MG / naloxone 2 MG Sublingual Film [Suboxone]" ] ], [ fhir:index 2 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1307058" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 4 MG / naloxone 1 MG Sublingual Film [Suboxone]" ] ], [ fhir:index 3 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1307063" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 12 MG / naloxone 3 MG Sublingual Film [Suboxone]" ] ], [ fhir:index 4 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1431083" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 1.4 MG / naloxone 0.36 MG Sublingual Tablet [Zubsolv]" ] ], [ fhir:index 5 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1431104" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 5.7 MG / naloxone 1.4 MG Sublingual Tablet [Zubsolv]" ] ], [ fhir:index 6 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1542396" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2.1 MG / naloxone 0.3 MG Buccal Film [Bunavail]" ] ], [ fhir:index 7 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1544853" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 4.2 MG / naloxone 0.7 MG Buccal Film [Bunavail]" ] ], [ fhir:index 8 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1544856" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 6.3 MG / naloxone 1 MG Buccal Film [Bunavail]" ] ], [ fhir:index 9 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1597570" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 11.4 MG / naloxone 2.9 MG Sublingual Tablet [Zubsolv]" ] ], [ fhir:index 10 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1597575" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 8.6 MG / naloxone 2.1 MG Sublingual Tablet [Zubsolv]" ] ], [ fhir:index 11 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1666385" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2.9 MG / naloxone 0.71 MG Sublingual Tablet [Zubsolv]" ] ], [ fhir:index 12 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1725064" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 40 MG/ML Nasal Spray [Narcan]" ] ], [ fhir:index 13 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1864414" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 0.7 MG / naloxone 0.18 MG Sublingual Tablet [Zubsolv]" ] ], [ fhir:index 14 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1870935" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 20 MG/ML Nasal Spray [Narcan]" ] ], [ fhir:index 15 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2540709" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 80 MG/ML Nasal Spray [Kloxxado]" ] ], [ fhir:index 16 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2589618" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "0.5 ML naloxone hydrochloride 10 MG/ML Prefilled Syringe [Zimhi]" ] ], [ fhir:index 17 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2680741" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 16 MG/ML Nasal Spray [Rextovy]" ] ], [ fhir:index 18 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1010600" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2 MG / naloxone 0.5 MG Sublingual Film" ] ], [ fhir:index 19 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1010604" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 8 MG / naloxone 2 MG Sublingual Film" ] ], [ fhir:index 20 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1191212" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 0.02 MG/ML Injectable Solution" ] ], [ fhir:index 21 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1191222" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 0.4 MG/ML Injectable Solution" ] ], [ fhir:index 22 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1191228" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 1 MG/ML Injectable Solution" ] ], [ fhir:index 23 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1191234" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "1 ML naloxone hydrochloride 0.4 MG/ML Cartridge" ] ], [ fhir:index 24 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1191250" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "2 ML naloxone hydrochloride 1 MG/ML Prefilled Syringe" ] ], [ fhir:index 25 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1307056" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 4 MG / naloxone 1 MG Sublingual Film" ] ], [ fhir:index 26 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1307061" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 12 MG / naloxone 3 MG Sublingual Film" ] ], [ fhir:index 27 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1431076" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 1.4 MG / naloxone 0.36 MG Sublingual Tablet" ] ], [ fhir:index 28 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1431102" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 5.7 MG / naloxone 1.4 MG Sublingual Tablet" ] ], [ fhir:index 29 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1542390" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2.1 MG / naloxone 0.3 MG Buccal Film" ] ], [ fhir:index 30 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1544851" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 4.2 MG / naloxone 0.7 MG Buccal Film" ] ], [ fhir:index 31 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1544854" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 6.3 MG / naloxone 1 MG Buccal Film" ] ], [ fhir:index 32 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1597568" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 11.4 MG / naloxone 2.9 MG Sublingual Tablet" ] ], [ fhir:index 33 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1597573" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 8.6 MG / naloxone 2.1 MG Sublingual Tablet" ] ], [ fhir:index 34 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1659929" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "1 ML naloxone hydrochloride 0.4 MG/ML Injection" ] ], [ fhir:index 35 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1666338" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2.9 MG / naloxone 0.71 MG Sublingual Tablet" ] ], [ fhir:index 36 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1725059" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 40 MG/ML Nasal Spray" ] ], [ fhir:index 37 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1855730" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "0.4 ML naloxone hydrochloride 5 MG/ML Auto-Injector" ] ], [ fhir:index 38 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1864412" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 0.7 MG / naloxone 0.18 MG Sublingual Tablet" ] ], [ fhir:index 39 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "1870933" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 20 MG/ML Nasal Spray" ] ], [ fhir:index 40 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2540703" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 80 MG/ML Nasal Spray" ] ], [ fhir:index 41 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2589612" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "0.5 ML naloxone hydrochloride 10 MG/ML Prefilled Syringe" ] ], [ fhir:index 42 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2596175" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "0.4 ML naloxone hydrochloride 25 MG/ML Auto-Injector" ] ], [ fhir:index 43 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2637879" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 16 MG/ML Nasal Spray" ] ], [ fhir:index 44 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2673091" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 30 MG/ML Nasal Spray" ] ], [ fhir:index 45 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2679504" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "1 ML naloxone hydrochloride 0.4 MG/ML Prefilled Syringe" ] ], [ fhir:index 46 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "2685612" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone hydrochloride 100 MG/ML Nasal Spray" ] ], [ fhir:index 47 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "312289" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "naloxone 0.5 MG / pentazocine 50 MG Oral Tablet" ] ], [ fhir:index 48 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "351266" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 2 MG / naloxone 0.5 MG Sublingual Tablet" ] ], [ fhir:index 49 ; fhir:ValueSet.expansion.contains.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ] ; fhir:ValueSet.expansion.contains.code [ fhir:value "351267" ] ; fhir:ValueSet.expansion.contains.display [ fhir:value "buprenorphine 8 MG / naloxone 2 MG Sublingual Tablet" ] ] ] . # - ontology header ------------------------------------------------------------ <http://hl7.org/fhir/ValueSet/naloxone-medications.ttl> a owl:Ontology ; owl:imports fhir:fhir.ttl ; owl:versionIRI <http://build.fhir.org/ValueSet/naloxone-medications.ttl> .
IG © 2019+ CDC / Security Risk Solutions, Inc. (SRS). Package fhir.cdc.opioid-cds-r4#2022.1.1 based on FHIR 4.0.1. Generated 2026-06-27
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