2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide
2022.1.1 - Release 2022.1

2022 CDC Clinical Practice Guideline for Prescribing Opioids Implementation Guide, published by CDC / Security Risk Solutions, Inc. (SRS). This guide is not an authorized publication; it is the continuous build for version 2022.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/security-rs/opioid-cds-r4/ and changes regularly. See the Directory of published versions

: General opiate urine drug screening tests - XML Representation

Active as of 2026-06-02

Raw xml | Download


<ValueSet xmlns="http://hl7.org/fhir">
  <id value="general-opiate-urine-drug-screening-tests"/>
  <meta>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-computablevalueset"/>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-executablevalueset"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ValueSet general-opiate-urine-drug-screening-tests</b></p><a name="general-opiate-urine-drug-screening-tests"> </a><a name="hcgeneral-opiate-urine-drug-screening-tests"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profiles: <a href="http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-computablevalueset.html">CPGComputableValueSet</a>, <a href="http://hl7.org/fhir/uv/cpg/STU1/StructureDefinition-cpg-executablevalueset.html">CPGExecutableValueSet</a></p></div><p style="border: black 1px dotted; background-color: #EEEEEE; padding: 8px; margin-bottom: 8px">Expansion based on Loinc v2.82</p><p>This value set contains 23 concepts</p><table class="codes"><tr><td><b>System</b></td><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b><a href="http://hl7.org/fhir/concept-properties#status">status</a></b></td></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-17384-9"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/17384-9/">17384-9</a></td><td>Opiates [Mass/volume] in Urine by Confirmatory method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-18390-5"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/18390-5/">18390-5</a></td><td>Opiates [Presence] in Urine by Confirmatory method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19138-7"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19138-7/">19138-7</a></td><td>Opiates cutoff [Mass/volume] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19295-5"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19295-5/">19295-5</a></td><td>Opiates [Presence] in Urine by Screen method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19296-3"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19296-3/">19296-3</a></td><td>Opiates tested for in Urine by Screen method Nominal</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19297-1"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19297-1/">19297-1</a></td><td>Opiates tested for in Urine by Screen method Narrative</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19298-9"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19298-9/">19298-9</a></td><td>Opiates positive [Identifier] in Urine by Confirmatory method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19299-7"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19299-7/">19299-7</a></td><td>Opiates cutoff [Mass/volume] in Urine for Screen method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19300-3"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19300-3/">19300-3</a></td><td>Opiates cutoff [Mass/volume] in Urine for Confirmatory method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19301-1"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19301-1/">19301-1</a></td><td>Opiates screen method [Identifier] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-19302-9"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/19302-9/">19302-9</a></td><td>Opiates confirm method [Identifier] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-21431-2"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/21431-2/">21431-2</a></td><td>Opiates [Presence] in Urine by Screen method &gt;2000 ng/mL</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-3879-4"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/3879-4/">3879-4</a></td><td>Opiates [Presence] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-41465-6"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/41465-6/">41465-6</a></td><td>Opiates/Creatinine [Mass Ratio] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-52952-9"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/52952-9/">52952-9</a></td><td>Opiates [Moles/volume] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-5706-7"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/5706-7/">5706-7</a></td><td>Opiates [Identifier] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-5707-5"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/5707-5/">5707-5</a></td><td>Deprecated Opiates [Identifier] in Urine</td><td>DEPRECATED</td></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-70150-8"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/70150-8/">70150-8</a></td><td>Opiates [Mass/volume] in Urine by Screen method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-70151-6"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/70151-6/">70151-6</a></td><td>Opiates [Presence] in Urine by Screen method &gt;300 ng/mL</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-8220-6"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/8220-6/">8220-6</a></td><td>Opiates [Mass/volume] in Urine</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-8221-4"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/8221-4/">8221-4</a></td><td>Opiates [Presence] in Urine by SAMHSA confirm method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-8222-2"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/8222-2/">8222-2</a></td><td>Opiates [Presence] in Urine by SAMHSA screen method</td><td/></tr><tr><td><a name="general-opiate-urine-drug-screening-tests-http://loinc.org-106506-9"> </a><code>http://loinc.org</code></td><td style="white-space:nowrap">  <a href="https://loinc.org/106506-9/">106506-9</a></td><td>Opiates panel - Urine by LC/MS/MS</td><td/></tr></table></div>
  </text>
  <extension
             url="http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-clinical-focus">
    <valueString
                 value="Presumed general urine tests for naturally occurring opioids (i.e. opiates) that are not specific to a particular substance based upon the inclusion of the word 'opiates' in the long name."/>
  </extension>
  <extension
             url="http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-dataelement-scope">
    <valueString value="Urine test"/>
  </extension>
  <extension
             url="http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-inclusion-criteria">
    <valueString value="Codes"/>
  </extension>
  <extension
             url="http://fhir.org/guides/cdc/opioid-cds/StructureDefinition/cdc-valueset-exclusion-criteria">
    <valueString value="None"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/valueset-author">
    <valueContactDetail>
      <name value="MD Partners, Inc."/>
      <telecom>
        <system value="email"/>
        <value value="info@mdpartners.com"/>
      </telecom>
    </valueContactDetail>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="computable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="executable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-usageWarning">
    <valueString
                 value="This value set contains a point-in-time expansion enumerating the codes that meet the value set intent. As new versions of the code systems used by the value set are released, the contents of this expansion will need to be updated to incorporate newly defined codes that meet the value set intent. Before, and periodically during production use, the value set expansion contents SHOULD be updated. The value set expansion specifies the timestamp when the expansion was produced, SHOULD contain the parameters used for the expansion, and SHALL contain the codes that are obtained by evaluating the value set definition. If this is ONLY an executable value set, a distributable definition of the value set must be obtained to compute the updated expansion."/>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/cqf-artifactComment">
    <extension url="type">
      <valueCode value="documentation"/>
    </extension>
    <extension url="text">
      <valueMarkdown
                     value="Maintenance search expression: `multiaxial_descendantsof:(LP14565-3 OR LP135742-7) AND system:urine`. The compose anchors at two trunk LP codes - LP14565-3 and LP135742-7 - using `concept is-a` filters scoped to SYSTEM=LP7681-2 (urine) and CLASSTYPE=1 (lab test). To regenerate: re-run the search expression as a LOINC hierarchy query, add any newly-discovered trunk LP code as another is-a filter, then re-expand."/>
    </extension>
  </extension>
  <url
       value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/general-opiate-urine-drug-screening-tests"/>
  <identifier>
    <system value="urn:ietf:rfc:3986"/>
    <value value="urn:oid:2.16.840.1.114222.48.16"/>
  </identifier>
  <version value="2022.1.1"/>
  <name value="GENERAL_OPIATE_URINE_DRUG_SCREENING_TESTS"/>
  <title value="General opiate urine drug screening tests"/>
  <status value="active"/>
  <experimental value="false"/>
  <date value="2026-06-02T09:32:14-06:00"/>
  <publisher value="CDC / Security Risk Solutions, Inc. (SRS)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="https://www.securityrisksolutions.com"/>
    </telecom>
  </contact>
  <description
               value="Presumed general urine tests for naturally occurring opioids (i.e. opiates) that are not specific to a particular substance based upon the inclusion of the word 'opiates' in the long name."/>
  <purpose
           value="Identification of urine drug tests where results can be used when considering pain management therapy"/>
  <copyright value="© CDC 2016+."/>
  <compose>
    <include>
      <system value="http://loinc.org"/>
      <filter>
        <property value="concept"/>
        <op value="is-a"/>
        <value value="LP14565-3"/>
      </filter>
      <filter>
        <property value="SYSTEM"/>
        <op value="="/>
        <value value="LP7681-2"/>
      </filter>
      <filter>
        <property value="CLASSTYPE"/>
        <op value="="/>
        <value value="1"/>
      </filter>
    </include>
    <include>
      <system value="http://loinc.org"/>
      <filter>
        <property value="concept"/>
        <op value="is-a"/>
        <value value="LP135742-7"/>
      </filter>
      <filter>
        <property value="SYSTEM"/>
        <op value="="/>
        <value value="LP7681-2"/>
      </filter>
      <filter>
        <property value="CLASSTYPE"/>
        <op value="="/>
        <value value="1"/>
      </filter>
    </include>
  </compose>
  <expansion>
    <extension
               url="http://hl7.org/fhir/5.0/StructureDefinition/extension-ValueSet.expansion.property">
      <extension url="code">
        <valueCode value="status"/>
      </extension>
      <extension url="uri">
        <valueUri value="http://hl7.org/fhir/concept-properties#status"/>
      </extension>
    </extension>
    <identifier value="urn:uuid:fecde73a-b86b-434b-bf55-e90f706d1949"/>
    <timestamp value="2026-06-02T15:32:14.317Z"/>
    <total value="23"/>
    <parameter>
      <name value="used-codesystem"/>
      <valueUri value="http://loinc.org|2.82"/>
    </parameter>
    <parameter>
      <name value="version"/>
      <valueUri value="http://loinc.org|2.82"/>
    </parameter>
    <contains>
      <system value="http://loinc.org"/>
      <code value="17384-9"/>
      <display value="Opiates [Mass/volume] in Urine by Confirmatory method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="18390-5"/>
      <display value="Opiates [Presence] in Urine by Confirmatory method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19138-7"/>
      <display value="Opiates cutoff [Mass/volume] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19295-5"/>
      <display value="Opiates [Presence] in Urine by Screen method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19296-3"/>
      <display value="Opiates tested for in Urine by Screen method Nominal"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19297-1"/>
      <display
               value="Opiates tested for in Urine by Screen method Narrative"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19298-9"/>
      <display
               value="Opiates positive [Identifier] in Urine by Confirmatory method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19299-7"/>
      <display
               value="Opiates cutoff [Mass/volume] in Urine for Screen method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19300-3"/>
      <display
               value="Opiates cutoff [Mass/volume] in Urine for Confirmatory method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19301-1"/>
      <display value="Opiates screen method [Identifier] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="19302-9"/>
      <display value="Opiates confirm method [Identifier] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="21431-2"/>
      <display
               value="Opiates [Presence] in Urine by Screen method &gt;2000 ng/mL"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="3879-4"/>
      <display value="Opiates [Presence] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="41465-6"/>
      <display value="Opiates/Creatinine [Mass Ratio] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="52952-9"/>
      <display value="Opiates [Moles/volume] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="5706-7"/>
      <display value="Opiates [Identifier] in Urine"/>
    </contains>
    <contains>
      <extension
                 url="http://hl7.org/fhir/5.0/StructureDefinition/extension-ValueSet.expansion.contains.property">
        <extension url="code">
          <valueCode value="status"/>
        </extension>
        <extension url="value">
          <valueCode value="DEPRECATED"/>
        </extension>
      </extension>
      <system value="http://loinc.org"/>
      <code value="5707-5"/>
      <display value="Deprecated Opiates [Identifier] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="70150-8"/>
      <display value="Opiates [Mass/volume] in Urine by Screen method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="70151-6"/>
      <display
               value="Opiates [Presence] in Urine by Screen method &gt;300 ng/mL"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="8220-6"/>
      <display value="Opiates [Mass/volume] in Urine"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="8221-4"/>
      <display value="Opiates [Presence] in Urine by SAMHSA confirm method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="8222-2"/>
      <display value="Opiates [Presence] in Urine by SAMHSA screen method"/>
    </contains>
    <contains>
      <system value="http://loinc.org"/>
      <code value="106506-9"/>
      <display value="Opiates panel - Urine by LC/MS/MS"/>
    </contains>
  </expansion>
</ValueSet>