mii-exa-mtb-kim-musterperson-bundle
type: Bundle
node role: treeRoot
id:
  v: mii-exa-mtb-kim-musterperson-bundle
type:
  v: transaction
entry:
  full url:
    v: http://example.org/fhir/ClinicalImpression/mii-exa-mtb-kim-musterperson-behandlungsepisode
    l: mii-exa-mtb-kim-musterperson-behandlungsepisode
  resource: mii-exa-mtb-kim-musterperson-behandlungsepisode
  request:
    method:
      v: PUT
    url:
      v: ClinicalImpression/mii-exa-mtb-kim-musterperson-behandlungsepisode
      l: mii-exa-mtb-kim-musterperson-behandlungsepisode
entry:
  full url:
    v: http://example.org/fhir/Observation/mii-exa-mtb-kim-musterperson-aufklaerung
    l: mii-exa-mtb-kim-musterperson-aufklaerung
  resource: mii-exa-mtb-kim-musterperson-aufklaerung
  request:
    method:
      v: PUT
    url:
      v: Observation/mii-exa-mtb-kim-musterperson-aufklaerung
      l: mii-exa-mtb-kim-musterperson-aufklaerung
entry:
  full url:
    v: http://example.org/fhir/Patient/PatientKimMusterperson
    l: PatientKimMusterperson
  resource: PatientKimMusterperson
  request:
    method:
      v: PUT
    url:
      v: Patient/PatientKimMusterperson
      l: PatientKimMusterperson
entry:
  full url:
    v: http://example.org/fhir/Observation/MTBObservationCA125-1
    l: MTBObservationCA125-1
  resource: MTBObservationCA125-1
  request:
    method:
      v: PUT
    url:
      v: Observation/MTBObservationCA125-1
      l: MTBObservationCA125-1
entry:
  full url:
    v: http://example.org/fhir/Observation/MTBObservationCA125-2
    l: MTBObservationCA125-2
  resource: MTBObservationCA125-2
  request:
    method:
      v: PUT
    url:
      v: Observation/MTBObservationCA125-2
      l: MTBObservationCA125-2
entry:
  full url:
    v: http://example.org/fhir/Observation/MTBObservationCA125-3
    l: MTBObservationCA125-3
  resource: MTBObservationCA125-3
  request:
    method:
      v: PUT
    url:
      v: Observation/MTBObservationCA125-3
      l: MTBObservationCA125-3
entry:
  full url:
    v: http://example.org/fhir/Observation/MTBObservationCA125-4
    l: MTBObservationCA125-4
  resource: MTBObservationCA125-4
  request:
    method:
      v: PUT
    url:
      v: Observation/MTBObservationCA125-4
      l: MTBObservationCA125-4
entry:
  full url:
    v: http://example.org/fhir/Observation/MTBObservationCA125-5
    l: MTBObservationCA125-5
  resource: MTBObservationCA125-5
  request:
    method:
      v: PUT
    url:
      v: Observation/MTBObservationCA125-5
      l: MTBObservationCA125-5
entry:
  full url:
    v: http://example.org/fhir/Observation/MTBObservationCA125-6
    l: MTBObservationCA125-6
  resource: MTBObservationCA125-6
  request:
    method:
      v: PUT
    url:
      v: Observation/MTBObservationCA125-6
      l: MTBObservationCA125-6
entry:
  full url:
    v: http://example.org/fhir/DiagnosticReport/PatientKimMusterperson-MolecularPathologyReport-1
    l: PatientKimMusterperson-MolecularPathologyReport-1
  resource: PatientKimMusterperson-MolecularPathologyReport-1
  request:
    method:
      v: PUT
    url:
      v: DiagnosticReport/PatientKimMusterperson-MolecularPathologyReport-1
      l: PatientKimMusterperson-MolecularPathologyReport-1
entry:
  full url:
    v: http://example.org/fhir/Specimen/PatientKimMusterperson-AscitesSpecimen-2
    l: PatientKimMusterperson-AscitesSpecimen-2
  resource: PatientKimMusterperson-AscitesSpecimen-2
  request:
    method:
      v: PUT
    url:
      v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
      l: PatientKimMusterperson-AscitesSpecimen-2
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
    l: PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
  resource: PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
      l: PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
    l: PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
  resource: PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
      l: PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
    l: PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
  resource: PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
      l: PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
    l: PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
  resource: PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
      l: PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-1-CA125
    l: PatientKimMusterperson-MolecularPathologyObservation-1-CA125
  resource: PatientKimMusterperson-MolecularPathologyObservation-1-CA125
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyObservation-1-CA125
      l: PatientKimMusterperson-MolecularPathologyObservation-1-CA125
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
    l: PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
  resource: PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
      l: PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
entry:
  full url:
    v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-3-WT1
    l: PatientKimMusterperson-MolecularPathologyObservation-3-WT1
  resource: PatientKimMusterperson-MolecularPathologyObservation-3-WT1
  request:
    method:
      v: PUT
    url:
      v: Observation/PatientKimMusterperson-MolecularPathologyObservation-3-WT1
      l: PatientKimMusterperson-MolecularPathologyObservation-3-WT1

mii-exa-mtb-kim-musterperson-behandlungsepisode
type: ClinicalImpression
id:
  v: mii-exa-mtb-kim-musterperson-behandlungsepisode
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-behandlungsepisode|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-behandlungsepisode
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ClinicalImpression mii-exa-mtb-kim-musterperson-behandlungsepisode Profile: MII PR MTB Behandlungsepisodeversion: null2026.0.0) status: Completed subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-01-20 --> 2023-03-28 problem: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet investigation code: Genetic finding item: Diagnostic Report for 'Genetic analysis report' for '->Kim Musterperson (no stated gender), DoB: 1956-03-14' investigation code: Pathology synoptic report item: Diagnostic Report for 'Pathology synoptic report' for '->Kim Musterperson (no stated gender), DoB: 1956-03-14' investigation code: ECOG performance status finding item: Observation 423740007 investigation code: Was consent given item: Observation Was consent given supportingInfo: Procedure Computertomographie [CT], nativ Observation Metastatic malignant neoplasm (disorder) Observation Recurrent Observation Ascites Observation Status post (contextual qualifier) (qualifier value) Procedure Computertomographie [CT], nativ Observation Status post (contextual qualifier) (qualifier value) Observation Ascites Observation Recurrent Observation Atypical Procedure Computertomographie [CT], nativ Observation Status post (contextual qualifier) (qualifier value) Observation Status post (contextual qualifier) (qualifier value) Observation Ascites Observation Recurrent Observation Recurrent Observation Mediastinal lymph node group Observation Mediastinal lymph node group Procedure Computertomographie [CT], nativ Procedure/PatientKimMusterperson-Procedure-4a Procedure/PatientKimMusterperson-Procedure-4b Procedure/PatientKimMusterperson-Procedure-4c Procedure/PatientKimMusterperson-Procedure-4d Observation Progressive Observation Entire peritoneal serous membrane of peritoneum Observation Carcinomatosis of peritoneum Observation True pelvis Procedure/PatientKimMusterperson-SystemicTherapy-1 Procedure/PatientKimMusterperson-SystemicTherapy-2 Procedu…
status:
  v: completed
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-01-20
  end:
    v: 2023-03-28
problem:
  l: mii-exa-mtb-kim-diagnose
  reference:
    v: Condition/mii-exa-mtb-kim-diagnose
investigation:
  code:
    coding: http://snomed.info/id/106221001
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 106221001
      display:
        v: Genetic finding
  item:
    l: mii-exa-mtb-kim-musterperson-ngs-bericht
    reference:
      v: DiagnosticReport/mii-exa-mtb-kim-musterperson-ngs-bericht
investigation:
  code:
    coding: https://loinc.org/rdf/60568-3
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 60568-3
      display:
        v: Pathology synoptic report
  item:
    l: PatientKimMusterperson-MolecularPathologyReport-1
    reference:
      v: DiagnosticReport/PatientKimMusterperson-MolecularPathologyReport-1
investigation:
  code:
    coding: http://snomed.info/id/424122007
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 424122007
      display:
        v: ECOG performance status finding
  item:
    l: mii-exa-onko-allgemeiner-leistungszustand-ecog
    reference:
      v: Observation/mii-exa-onko-allgemeiner-leistungszustand-ecog
investigation:
  code:
    coding: https://loinc.org/rdf/105511-0
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 105511-0
      display:
        v: Was consent given
  item:
    l: mii-exa-mtb-kim-musterperson-aufklaerung
    reference:
      v: Observation/mii-exa-mtb-kim-musterperson-aufklaerung
supporting info:
  l: PatientKimMusterperson-Procedure-1
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-1
supporting info:
  l: PatientKimMusterperson-Observation-1
  reference:
    v: Observation/PatientKimMusterperson-Observation-1
supporting info:
  l: PatientKimMusterperson-Observation-2
  reference:
    v: Observation/PatientKimMusterperson-Observation-2
supporting info:
  l: PatientKimMusterperson-Observation-3
  reference:
    v: Observation/PatientKimMusterperson-Observation-3
supporting info:
  l: PatientKimMusterperson-Observation-4
  reference:
    v: Observation/PatientKimMusterperson-Observation-4
supporting info:
  l: PatientKimMusterperson-Procedure-2
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-2
supporting info:
  l: PatientKimMusterperson-Observation-5
  reference:
    v: Observation/PatientKimMusterperson-Observation-5
supporting info:
  l: PatientKimMusterperson-Observation-6
  reference:
    v: Observation/PatientKimMusterperson-Observation-6
supporting info:
  l: PatientKimMusterperson-Observation-7
  reference:
    v: Observation/PatientKimMusterperson-Observation-7
supporting info:
  l: PatientKimMusterperson-Observation-8
  reference:
    v: Observation/PatientKimMusterperson-Observation-8
supporting info:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
supporting info:
  l: PatientKimMusterperson-Observation-9
  reference:
    v: Observation/PatientKimMusterperson-Observation-9
supporting info:
  l: PatientKimMusterperson-Observation-10
  reference:
    v: Observation/PatientKimMusterperson-Observation-10
supporting info:
  l: PatientKimMusterperson-Observation-11
  reference:
    v: Observation/PatientKimMusterperson-Observation-11
supporting info:
  l: PatientKimMusterperson-Observation-12
  reference:
    v: Observation/PatientKimMusterperson-Observation-12
supporting info:
  l: PatientKimMusterperson-Observation-13
  reference:
    v: Observation/PatientKimMusterperson-Observation-13
supporting info:
  l: PatientKimMusterperson-Observation-14
  reference:
    v: Observation/PatientKimMusterperson-Observation-14
supporting info:
  l: PatientKimMusterperson-Observation-15
  reference:
    v: Observation/PatientKimMusterperson-Observation-15
supporting info:
  l: PatientKimMusterperson-Procedure-4
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4
supporting info:
  l: PatientKimMusterperson-Procedure-4a
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4a
supporting info:
  l: PatientKimMusterperson-Procedure-4b
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4b
supporting info:
  l: PatientKimMusterperson-Procedure-4c
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4c
supporting info:
  l: PatientKimMusterperson-Procedure-4d
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4d
supporting info:
  l: PatientKimMusterperson-Observation-16
  reference:
    v: Observation/PatientKimMusterperson-Observation-16
supporting info:
  l: PatientKimMusterperson-Observation-17
  reference:
    v: Observation/PatientKimMusterperson-Observation-17
supporting info:
  l: PatientKimMusterperson-Observation-18
  reference:
    v: Observation/PatientKimMusterperson-Observation-18
supporting info:
  l: PatientKimMusterperson-Observation-19
  reference:
    v: Observation/PatientKimMusterperson-Observation-19
supporting info:
  l: PatientKimMusterperson-SystemicTherapy-1
  reference:
    v: Procedure/PatientKimMusterperson-SystemicTherapy-1
supporting info:
  l: PatientKimMusterperson-SystemicTherapy-2
  reference:
    v: Procedure/PatientKimMusterperson-SystemicTherapy-2
supporting info:
  l: PatientKimMusterperson-SystemicTherapy-3

mii-exa-mtb-kim-musterperson-aufklaerung
type: Observation
id:
  v: mii-exa-mtb-kim-musterperson-aufklaerung
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-consent-given|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-consent-given
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-musterperson-aufklaerung Profile: MII PR MTB Consentversion: null2026.0.0) status: Final code: Was consent given subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-01-02 value: Yes (qualifier value)
status:
  v: final
code:
  coding: https://loinc.org/rdf/105511-0
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 105511-0
    display:
      v: Was consent given
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-01-02
value: CodeableConcept
  coding: http://snomed.info/id/373066001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 373066001
    display:
      v: Yes (qualifier value)

PatientKimMusterperson
type: Patient
id:
  v: PatientKimMusterperson
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Patient PatientKimMusterperson Kim Musterperson (no stated gender), DoB: 1956-03-14
name:
  family:
    v: Musterperson
  given:
    v: Kim
birth date:
  v: 1956-03-14

MTBObservationCA125-1
type: Observation
id:
  v: MTBObservationCA125-1
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MTBObservationCA125-1 status: Final category: Laboratory studies (set), Labor code: Cancer Ag 125 [Units/volume] in Body fluid subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2022-04-22 value: 42.3 IU/ml (Details: UCUM code[iU]/ml = '[iU]/ml')
status:
  v: final
category:
  coding: https://loinc.org/rdf/26436-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 26436-6
    display:
      v: Laboratory studies (set)
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
code:
  coding: https://loinc.org/rdf/11210-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 11210-2
    display:
      v: Cancer Ag 125 [Units/volume] in Body fluid
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2022-04-22
value: Quantity
  value:
    v: 42.3
  unit:
    v: IU/ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: [iU]/ml

MTBObservationCA125-2
type: Observation
id:
  v: MTBObservationCA125-2
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MTBObservationCA125-2 status: Final category: Laboratory studies (set), Labor code: Cancer Ag 125 [Units/volume] in Body fluid subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2022-07-18 value: 45.8 IU/ml (Details: UCUM code[iU]/ml = '[iU]/ml')
status:
  v: final
category:
  coding: https://loinc.org/rdf/26436-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 26436-6
    display:
      v: Laboratory studies (set)
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
code:
  coding: https://loinc.org/rdf/11210-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 11210-2
    display:
      v: Cancer Ag 125 [Units/volume] in Body fluid
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2022-07-18
value: Quantity
  value:
    v: 45.8
  unit:
    v: IU/ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: [iU]/ml

MTBObservationCA125-3
type: Observation
id:
  v: MTBObservationCA125-3
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MTBObservationCA125-3 status: Final category: Laboratory studies (set), Labor code: Cancer Ag 125 [Units/volume] in Body fluid subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2022-10-24 value: 49.7 IU/ml (Details: UCUM code[iU]/ml = '[iU]/ml')
status:
  v: final
category:
  coding: https://loinc.org/rdf/26436-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 26436-6
    display:
      v: Laboratory studies (set)
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
code:
  coding: https://loinc.org/rdf/11210-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 11210-2
    display:
      v: Cancer Ag 125 [Units/volume] in Body fluid
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2022-10-24
value: Quantity
  value:
    v: 49.7
  unit:
    v: IU/ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: [iU]/ml

MTBObservationCA125-4
type: Observation
id:
  v: MTBObservationCA125-4
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MTBObservationCA125-4 status: Final category: Laboratory studies (set), Labor code: Cancer Ag 125 [Units/volume] in Body fluid subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2022-12-27 value: 67.2 IU/ml (Details: UCUM code[iU]/ml = '[iU]/ml')
status:
  v: final
category:
  coding: https://loinc.org/rdf/26436-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 26436-6
    display:
      v: Laboratory studies (set)
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
code:
  coding: https://loinc.org/rdf/11210-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 11210-2
    display:
      v: Cancer Ag 125 [Units/volume] in Body fluid
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2022-12-27
value: Quantity
  value:
    v: 67.2
  unit:
    v: IU/ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: [iU]/ml

MTBObservationCA125-5
type: Observation
id:
  v: MTBObservationCA125-5
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MTBObservationCA125-5 status: Final category: Laboratory studies (set), Labor code: Cancer Ag 125 [Units/volume] in Body fluid subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-24 value: 43.7 IU/ml (Details: UCUM code[iU]/ml = '[iU]/ml')
status:
  v: final
category:
  coding: https://loinc.org/rdf/26436-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 26436-6
    display:
      v: Laboratory studies (set)
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
code:
  coding: https://loinc.org/rdf/11210-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 11210-2
    display:
      v: Cancer Ag 125 [Units/volume] in Body fluid
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-24
value: Quantity
  value:
    v: 43.7
  unit:
    v: IU/ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: [iU]/ml

MTBObservationCA125-6
type: Observation
id:
  v: MTBObservationCA125-6
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MTBObservationCA125-6 status: Final category: Laboratory studies (set), Labor code: Cancer Ag 125 [Units/volume] in Body fluid subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-06-20 value: 78.2 IU/ml (Details: UCUM code[iU]/ml = '[iU]/ml')
status:
  v: final
category:
  coding: https://loinc.org/rdf/26436-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 26436-6
    display:
      v: Laboratory studies (set)
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
code:
  coding: https://loinc.org/rdf/11210-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 11210-2
    display:
      v: Cancer Ag 125 [Units/volume] in Body fluid
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-06-20
value: Quantity
  value:
    v: 78.2
  unit:
    v: IU/ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: [iU]/ml

PatientKimMusterperson-MolecularPathologyReport-1
type: DiagnosticReport
id:
  v: PatientKimMusterperson-MolecularPathologyReport-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molecular-pathology-report|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molecular-pathology-report
text:
  status:
    v: generated
  div:
    v: Generated Narrative: DiagnosticReport PatientKimMusterperson-MolecularPathologyReport-1 Profile: MII PR MTB Molecular Pathology Reportversion: null2026.0.0) Pathology synoptic report Subject Kim Musterperson (no stated gender), DoB: 1956-03-14 Report Details Code Value Flags HER2 Ag [Presence] in Tissue by Immune stain 2+ Final
status:
  v: final
code:
  coding: https://loinc.org/rdf/60568-3
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 60568-3
    display:
      v: Pathology synoptic report
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
result:
  l: PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
  reference:
    v: Observation/PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu

PatientKimMusterperson-AscitesSpecimen-2
type: Specimen
id:
  v: PatientKimMusterperson-AscitesSpecimen-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-specimen
    l: mii-pr-onko-specimen
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Specimen PatientKimMusterperson-AscitesSpecimen-2 Profile: MII PR Onkologie Specimen accessionIdentifier: Z230201/23 type: Ascitic fluid specimen (specimen) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 Collections - Collected[x] * 2023-02-01
accession identifier:
  value:
    v: Z230201/23
type:
  coding: http://snomed.info/id/309201001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 309201001
    display:
      v: Ascitic fluid specimen (specimen)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
collection:
  collected: DateTime
    v: 2023-02-01

PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-0a-Her2neu Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, Genetik, A characterization of a given biomarker observation. code: HER2 Ag [Presence] in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: 2+ specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen) Components - Code Value[x] * Gene studied [ID] ERBB2
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/18474-7
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 18474-7
    display:
      v: HER2 Ag [Presence] in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA11842-4
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA11842-4
    display:
      v: 2+
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:3430
      display:
        v: ERBB2

PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyInterpret-0a-Her2neu Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: HER2 [Interpretation] in Tissue subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: HER2-low (IHC 2+/ISH negative) specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen) Components - Code Value[x] * Gene studied [ID] ERBB2
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/48676-1
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 48676-1
    display:
      v: HER2 [Interpretation] in Tissue
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: http://snomed.info/id/1381317004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1381317004
    display:
      v: Human epidermal growth factor receptor 2 low
  text:
    v: HER2-low (IHC 2+/ISH negative)
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:3430
      display:
        v: ERBB2

PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-0b-Folat-Ra Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: Immune stain study subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: 70 % (Details: UCUM code{/100} = '{/100}') specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen) Components - Code Value[x] * Gene studied [ID] FOLR1
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/55229-9
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 55229-9
    display:
      v: Immune stain study
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: Quantity
  value:
    v: 70
  unit:
    v: %
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: {/100}
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:3791
      display:
        v: FOLR1
    coding: LP440974-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: LP440974-6
      display:
        v: Folate receptor alpha

PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-0c-Trop2 Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: Immune stain study subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Positive specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen) Components - Code Value[x] * Gene studied [ID] TACSTD2
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/55229-9
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 55229-9
    display:
      v: Immune stain study
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA6576-8
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA6576-8
    display:
      v: Positive
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:11530
      display:
        v: TACSTD2
    coding:
      system:
        v: http://www.uniprot.org
        l: www.uniprot.org
      code:
        v: P09758
      display:
        v: Tumor-associated calcium signal transducer 2

PatientKimMusterperson-MolecularPathologyObservation-1-CA125
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-1-CA125
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-1-CA125 Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: Cancer Ag 125 [Presence] in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Die Tumorzellen sind partiell positiv für CA125,... specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen) Components - Code Value[x] * Gene studied [ID] TACSTD2
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/48677-9
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 48677-9
    display:
      v: Cancer Ag 125 [Presence] in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA6576-8
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA6576-8
    display:
      v: Positive
  text:
    v: Die Tumorzellen sind partiell positiv für CA125,...
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:11530
      display:
        v: TACSTD2
    coding:
      system:
        v: http://www.uniprot.org
        l: www.uniprot.org
      code:
        v: P09758
      display:
        v: Tumor-associated calcium signal transducer 2

PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-2-Pax8
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-2-Pax8 Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: PAX8 Ag [Presence] in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Tumorzellen durchgehend nukleär für Pax 8 specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/73910-2
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 73910-2
    display:
      v: PAX8 Ag [Presence] in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA6576-8
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA6576-8
    display:
      v: Positive
  text:
    v: Tumorzellen durchgehend nukleär für Pax 8
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

PatientKimMusterperson-MolecularPathologyObservation-3-WT1
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-3-WT1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-3-WT1 Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: Observation using immunohistochemistry (observable entity) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Tumorzellen durchgehend nukleär für WT1 bodySite: Nukleär specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen) Components - Code Value[x] * Gene studied [ID] WT1
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA6576-8
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA6576-8
    display:
      v: Positive
  text:
    v: Tumorzellen durchgehend nukleär für WT1
body site:
  coding: http://snomed.info/id/84640000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 84640000
    display:
      v: Nucleus (cell structure)
  text:
    v: Nukleär
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:12796
      display:
        v: WT1
    coding: LP65352-4
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: LP65352-4
      display:
        v: WT-1 Ag

PatientKimMusterperson-MolecularPathologyObservation-4-ER
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-4-ER
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-4-ER Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: Cells.estrogen receptor/cells in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: 70 % (Details: UCUM code/100 = '/100') specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/14228-1
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 14228-1
    display:
      v: Cells.estrogen receptor/cells in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: Quantity
  value:
    v: 70
  unit:
    v: %
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: /100
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

PatientKimMusterperson-MolecularPathologyObservation-5-PR
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-5-PR
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-5-PR Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: Cells.progesterone receptor/cells in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: 30 % (Details: UCUM code/100 = '/100') specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/14230-7
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 14230-7
    display:
      v: Cells.progesterone receptor/cells in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: Quantity
  value:
    v: 30
  unit:
    v: %
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: /100
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

PatientKimMusterperson-MolecularPathologyObservation-6-p53
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-6-p53
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-6-p53 Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: P53 protein Ag [Presence] in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Kräftige nukleäre Überexpression von p53 specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/14229-9
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 14229-9
    display:
      v: P53 protein Ag [Presence] in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA6576-8
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA6576-8
    display:
      v: Positive
  text:
    v: Kräftige nukleäre Überexpression von p53
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

PatientKimMusterperson-MolecularPathologyObservation-7-p53
type: Observation
id:
  v: PatientKimMusterperson-MolecularPathologyObservation-7-p53
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-MolecularPathologyObservation-7-p53 Profile: MII PR MTB Immunohistochemistryversion: null2026.0.0) status: Final category: Labor, A characterization of a given biomarker observation. code: P53 protein Ag [Presence] in Tissue by Immune stain subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Kräftige nukleäre Überexpression von p53 specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
category:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: biomarker-category
code:
  coding: https://loinc.org/rdf/14229-9
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 14229-9
    display:
      v: P53 protein Ag [Presence] in Tissue by Immune stain
  coding: http://snomed.info/id/1234806008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1234806008
    display:
      v: Observation using immunohistochemistry (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA6576-8
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA6576-8
    display:
      v: Positive
  text:
    v: Kräftige nukleäre Überexpression von p53
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

PatientKimMusterperson-Procedure-1
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-1 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2022-04-20 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2022-04-20
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Procedure-2
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-2 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2022-07-15 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2022-07-15
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Procedure-3
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-3
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-3 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2022-10-22 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2022-10-22
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Procedure-4
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-4
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-4 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2022-12-19 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2022-12-19
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Procedure-5
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-5
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-5 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2023-03-20 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2023-03-20
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Procedure-6
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-6
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-6 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2023-08-20 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2023-08-20
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Procedure-7
type: Procedure
id:
  v: PatientKimMusterperson-Procedure-7
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-prozedur/StructureDefinition/Procedure
    l: Procedure
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure PatientKimMusterperson-Procedure-7 Profile: MII PR Prozedur Procedure status: Completed category: Radiographic imaging procedure code: Computertomographie [CT], nativ subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2023-10-22 bodySite: Abdomen, Thoracic structure
status:
  v: completed
category:
  coding: http://snomed.info/id/363680008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 363680008
    display:
      v: Radiographic imaging procedure
code:
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2025
    code:
      v: 3-20
    display:
      v: Computertomographie [CT], nativ
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: DateTime
  v: 2023-10-22
body site:
  coding: http://snomed.info/id/818983003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 818983003
    display:
      v: Abdomen
body site:
  coding: http://snomed.info/id/51185008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 51185008
    display:
      v: Thoracic structure

PatientKimMusterperson-Observation-1
type: Observation
id:
  v: PatientKimMusterperson-Observation-1
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-1 partOf: Procedure Computertomographie [CT], nativ status: Final code: Metastatic malignant neoplasm (disorder) value: kein Hinweis auf thorakale Metastasierung
part of:
  l: PatientKimMusterperson-Procedure-1
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-1
status:
  v: final
code:
  coding: http://snomed.info/id/128462008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 128462008
    display:
      v: Metastatic malignant neoplasm (disorder)
value: CodeableConcept
  coding: http://snomed.info/id/41647002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 41647002
    display:
      v: No evidence of (contextual qualifier) (qualifier value)
  text:
    v: kein Hinweis auf thorakale Metastasierung

PatientKimMusterperson-Observation-2
type: Observation
id:
  v: PatientKimMusterperson-Observation-2
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-2 partOf: Procedure Computertomographie [CT], nativ status: Final code: Recurrent value: kein Hinweis auf Lokalrezidiv
part of:
  l: PatientKimMusterperson-Procedure-1
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-1
status:
  v: final
code:
  coding: http://snomed.info/id/255227004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255227004
    display:
      v: Recurrent
value: CodeableConcept
  coding: http://snomed.info/id/41647002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 41647002
    display:
      v: No evidence of (contextual qualifier) (qualifier value)
  text:
    v: kein Hinweis auf Lokalrezidiv

PatientKimMusterperson-Observation-3
type: Observation
id:
  v: PatientKimMusterperson-Observation-3
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-3 partOf: Procedure Computertomographie [CT], nativ status: Final code: Ascites value: kein Aszites
part of:
  l: PatientKimMusterperson-Procedure-1
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-1
status:
  v: final
code:
  coding: http://snomed.info/id/389026000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 389026000
    display:
      v: Ascites
value: CodeableConcept
  coding: http://snomed.info/id/860638000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 860638000
    display:
      v: No ascites
  text:
    v: kein Aszites

PatientKimMusterperson-Observation-4
type: Observation
id:
  v: PatientKimMusterperson-Observation-4
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-4 partOf: Procedure Computertomographie [CT], nativ status: Final code: Status post (contextual qualifier) (qualifier value) value: Flüssigkeitskollektion angrenzend DD postoperativ bodySite: Entire duodenum
part of:
  l: PatientKimMusterperson-Procedure-1
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-1
status:
  v: final
code:
  coding: http://snomed.info/id/237679004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 237679004
    display:
      v: Status post (contextual qualifier) (qualifier value)
  coding: http://snomed.info/id/112231000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 112231000
    display:
      v: Atypical (qualifier value)
  coding: http://snomed.info/id/174430004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 174430004
    display:
      v: Resection of segment of liver (procedure)
value: CodeableConcept
  coding: http://snomed.info/id/309201001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 309201001
    display:
      v: Ascitic fluid specimen
  coding: http://snomed.info/id/262061000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 262061000
    display:
      v: After surgery
  text:
    v: Flüssigkeitskollektion angrenzend DD postoperativ
body site:
  coding: http://snomed.info/id/181247007
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 181247007
    display:
      v: Entire duodenum

PatientKimMusterperson-Observation-5
type: Observation
id:
  v: PatientKimMusterperson-Observation-5
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-5 partOf: Procedure Computertomographie [CT], nativ status: Final code: Status post (contextual qualifier) (qualifier value) value: konstante Flüssigkeitskollektion angrenzend bodySite: Entire duodenum
part of:
  l: PatientKimMusterperson-Procedure-2
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-2
status:
  v: final
code:
  coding: http://snomed.info/id/237679004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 237679004
    display:
      v: Status post (contextual qualifier) (qualifier value)
  coding: http://snomed.info/id/112231000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 112231000
    display:
      v: Atypical
  coding: http://snomed.info/id/174430004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 174430004
    display:
      v: Resection of segment of liver (procedure)
value: CodeableConcept
  coding: http://snomed.info/id/420341009
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 420341009
    display:
      v: Constant
  coding: http://snomed.info/id/309201001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 309201001
    display:
      v: Ascitic fluid specimen
  text:
    v: konstante Flüssigkeitskollektion angrenzend
body site:
  coding: http://snomed.info/id/181247007
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 181247007
    display:
      v: Entire duodenum

PatientKimMusterperson-Observation-6
type: Observation
id:
  v: PatientKimMusterperson-Observation-6
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-6 partOf: Procedure Computertomographie [CT], nativ status: Final code: Ascites value: kein Aszites
part of:
  l: PatientKimMusterperson-Procedure-2
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-2
status:
  v: final
code:
  coding: http://snomed.info/id/389026000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 389026000
    display:
      v: Ascites
value: CodeableConcept
  coding: http://snomed.info/id/860638000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 860638000
    display:
      v: No ascites
  text:
    v: kein Aszites

PatientKimMusterperson-Observation-7
type: Observation
id:
  v: PatientKimMusterperson-Observation-7
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-7 partOf: Procedure Computertomographie [CT], nativ status: Final code: Recurrent value: kein Hinweis auf Lokalrezidiv
part of:
  l: PatientKimMusterperson-Procedure-2
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-2
status:
  v: final
code:
  coding: http://snomed.info/id/255227004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255227004
    display:
      v: Recurrent
value: CodeableConcept
  coding: http://snomed.info/id/41647002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 41647002
    display:
      v: No evidence of (contextual qualifier) (qualifier value)
  text:
    v: kein Hinweis auf Lokalrezidiv

PatientKimMusterperson-Observation-8
type: Observation
id:
  v: PatientKimMusterperson-Observation-8
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-8 partOf: Procedure Computertomographie [CT], nativ status: Final code: im linken Oberlappen der Lunge diskrete milchglasartige Trübung value: kein Hinweis auf thorakale Filiae
part of:
  l: PatientKimMusterperson-Procedure-2
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-2
status:
  v: final
code:
  coding: http://snomed.info/id/112231000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 112231000
    display:
      v: Atypical
  coding: http://snomed.info/id/1217294009
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1217294009
    display:
      v: Ground glass opacity
  coding: http://snomed.info/id/44714003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 44714003
    display:
      v: Structure of upper lobe of left lung
  text:
    v: im linken Oberlappen der Lunge diskrete milchglasartige Trübung
value: CodeableConcept
  coding: http://snomed.info/id/41647002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 41647002
    display:
      v: No evidence of (contextual qualifier) (qualifier value)
  coding: http://snomed.info/id/255058005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255058005
    display:
      v: Neoplasm of thorax
  text:
    v: kein Hinweis auf thorakale Filiae

PatientKimMusterperson-Observation-9
type: Observation
id:
  v: PatientKimMusterperson-Observation-9
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-9 partOf: Procedure Computertomographie [CT], nativ status: Final code: Status post (contextual qualifier) (qualifier value) value: regrediente Flüssigkeitskollektion am Leberrand bodySite: Entire liver
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/237679004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 237679004
    display:
      v: Status post (contextual qualifier) (qualifier value)
  coding: http://snomed.info/id/112231000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 112231000
    display:
      v: Atypical
  coding: http://snomed.info/id/174430004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 174430004
    display:
      v: Resection of segment of liver (procedure)
value: CodeableConcept
  coding: http://snomed.info/id/309201001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 309201001
    display:
      v: Ascitic fluid specimen
  coding: http://snomed.info/id/249567002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 249567002
    display:
      v: Liver edge (finding)
  text:
    v: regrediente Flüssigkeitskollektion am Leberrand
body site:
  coding: http://snomed.info/id/181268008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 181268008
    display:
      v: Entire liver

PatientKimMusterperson-Observation-10
type: Observation
id:
  v: PatientKimMusterperson-Observation-10
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-10 partOf: Procedure Computertomographie [CT], nativ status: Final code: Status post (contextual qualifier) (qualifier value) value: Darüberhinaus kein Hinweis auf Leberfilialisierung. bodySite: Entire liver
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/237679004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 237679004
    display:
      v: Status post (contextual qualifier) (qualifier value)
  coding: http://snomed.info/id/112231000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 112231000
    display:
      v: Atypical
  coding: http://snomed.info/id/174430004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 174430004
    display:
      v: Resection of segment of liver (procedure)
value: CodeableConcept
  coding: http://snomed.info/id/94381002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 94381002
    display:
      v: Metastatic malignant neoplasm to liver (disorder)
  coding: http://snomed.info/id/41647002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 41647002
    display:
      v: No evidence of (contextual qualifier) (qualifier value)
  text:
    v: Darüberhinaus kein Hinweis auf Leberfilialisierung.
body site:
  coding: http://snomed.info/id/181268008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 181268008
    display:
      v: Entire liver

PatientKimMusterperson-Observation-11
type: Observation
id:
  v: PatientKimMusterperson-Observation-11
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-11 partOf: Procedure Computertomographie [CT], nativ status: Final code: Ascites value: kein Aszites
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/389026000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 389026000
    display:
      v: Ascites
value: CodeableConcept
  coding: http://snomed.info/id/860638000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 860638000
    display:
      v: No ascites
  text:
    v: kein Aszites

PatientKimMusterperson-Observation-12
type: Observation
id:
  v: PatientKimMusterperson-Observation-12
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-12 partOf: Procedure Computertomographie [CT], nativ status: Final code: Recurrent value: kein Hinweis auf Lokalrezidiv
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/255227004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255227004
    display:
      v: Recurrent
value: CodeableConcept
  coding: http://snomed.info/id/41647002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 41647002
    display:
      v: No evidence of (contextual qualifier) (qualifier value)
  text:
    v: kein Hinweis auf Lokalrezidiv

PatientKimMusterperson-Observation-13
type: Observation
id:
  v: PatientKimMusterperson-Observation-13
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-13 partOf: Procedure Computertomographie [CT], nativ status: Final code: regrediente Milchglasinfiltrate im linken Oberlappen value: a.e. atypisch entzündlich
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/255227004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255227004
    display:
      v: Recurrent
  coding: http://snomed.info/id/1217294009
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 1217294009
    display:
      v: Ground glass opacity
  coding: http://snomed.info/id/44714003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 44714003
    display:
      v: Structure of upper lobe of left lung
  text:
    v: regrediente Milchglasinfiltrate im linken Oberlappen
value: CodeableConcept
  coding: http://snomed.info/id/112231000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 112231000
    display:
      v: Atypical
  coding: http://snomed.info/id/257552002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 257552002
    display:
      v: Inflammation
  text:
    v: a.e. atypisch entzündlich

PatientKimMusterperson-Observation-14
type: Observation
id:
  v: PatientKimMusterperson-Observation-14
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-14 partOf: Procedure Computertomographie [CT], nativ status: Final code: mediastinaler Lymphknoten value: vermehrter mediastinaler Lymphknotenbesatz ohne Kontrastmittelaufnahme
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/245276004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 245276004
    display:
      v: Mediastinal lymph node group
  text:
    v: mediastinaler Lymphknoten
value: CodeableConcept
  coding: http://snomed.info/id/258283002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 258283002
    display:
      v: Lymphomatous nodal involvement
  coding: http://snomed.info/id/373067005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 373067005
    display:
      v: No
  coding: http://snomed.info/id/385420005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 385420005
    display:
      v: Contrast media
  coding: http://snomed.info/id/151174005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 151174005
    display:
      v: Drug intake observed
  text:
    v: vermehrter mediastinaler Lymphknotenbesatz ohne Kontrastmittelaufnahme

PatientKimMusterperson-Observation-15
type: Observation
id:
  v: PatientKimMusterperson-Observation-15
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-15 partOf: Procedure Computertomographie [CT], nativ status: Final code: mediastinaler Lymphknoten value: ohne pathologische Vergrößerung
part of:
  l: PatientKimMusterperson-Procedure-3
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-3
status:
  v: final
code:
  coding: http://snomed.info/id/245276004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 245276004
    display:
      v: Mediastinal lymph node group
  text:
    v: mediastinaler Lymphknoten
value: CodeableConcept
  coding: http://snomed.info/id/373067005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 373067005
    display:
      v: No
  coding: http://snomed.info/id/15454001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 15454001
    display:
      v: Increased size
  text:
    v: ohne pathologische Vergrößerung

PatientKimMusterperson-Observation-16
type: Observation
id:
  v: PatientKimMusterperson-Observation-16
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-16 partOf: Procedure Computertomographie [CT], nativ status: Final code: Progredienter Aszites value: 700 ml (Details: UCUM codemL = 'mL')
part of:
  l: PatientKimMusterperson-Procedure-4
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4
status:
  v: final
code:
  coding: http://snomed.info/id/255314001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255314001
    display:
      v: Progressive
  text:
    v: Progredienter Aszites
value: Quantity
  value:
    v: 700
  unit:
    v: ml
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: mL

PatientKimMusterperson-Observation-17
type: Observation
id:
  v: PatientKimMusterperson-Observation-17
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-17 partOf: Procedure Computertomographie [CT], nativ status: Final code: Peritonealblatt value: Peritonealblatt mit zunehmender, unregelmäßiger KM-Aufnahme
part of:
  l: PatientKimMusterperson-Procedure-4
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4
status:
  v: final
code:
  coding: http://snomed.info/id/362700006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 362700006
    display:
      v: Entire peritoneal serous membrane of peritoneum
  text:
    v: Peritonealblatt
value: CodeableConcept
  coding: http://snomed.info/id/385420005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 385420005
    display:
      v: Contrast media
  coding: http://snomed.info/id/49608001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 49608001
    display:
      v: Irregular
  coding: http://snomed.info/id/260366006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 260366006
    display:
      v: Increase
  coding: http://snomed.info/id/151174005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 151174005
    display:
      v: Drug intake observed
  text:
    v: Peritonealblatt mit zunehmender, unregelmäßiger KM-Aufnahme

PatientKimMusterperson-Observation-18
type: Observation
id:
  v: PatientKimMusterperson-Observation-18
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-18 partOf: Procedure Computertomographie [CT], nativ status: Final code: Peritonealkarzinose value: Progress
part of:
  l: PatientKimMusterperson-Procedure-4
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4
status:
  v: final
code:
  coding: http://snomed.info/id/836274002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 836274002
    display:
      v: Carcinomatosis of peritoneum
  text:
    v: Peritonealkarzinose
value: CodeableConcept
  coding: http://snomed.info/id/255314001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255314001
    display:
      v: Progressive
  text:
    v: Progress

PatientKimMusterperson-Observation-19
type: Observation
id:
  v: PatientKimMusterperson-Observation-19
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-19 partOf: Procedure Computertomographie [CT], nativ status: Final code: kleinen Becken value: Lokalrezidiv bei kontrastmittelaufnehmender Raumforderung
part of:
  l: PatientKimMusterperson-Procedure-4
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-4
status:
  v: final
code:
  coding: http://snomed.info/id/80266002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 80266002
    display:
      v: True pelvis
  text:
    v: kleinen Becken
value: CodeableConcept
  coding: http://snomed.info/id/255227004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255227004
    display:
      v: Recurrent
  text:
    v: Lokalrezidiv bei kontrastmittelaufnehmender Raumforderung

PatientKimMusterperson-Observation-20
type: Observation
id:
  v: PatientKimMusterperson-Observation-20
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-20 partOf: Procedure Computertomographie [CT], nativ status: Final code: Aszites value: Regredient
part of:
  l: PatientKimMusterperson-Procedure-5
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-5
status:
  v: final
code:
  coding: http://snomed.info/id/389026000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 389026000
    display:
      v: Ascites
  text:
    v: Aszites
value: CodeableConcept
  coding: http://snomed.info/id/37865006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 37865006
    display:
      v: Regressive
  text:
    v: Regredient

PatientKimMusterperson-Observation-21
type: Observation
id:
  v: PatientKimMusterperson-Observation-21
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-21 partOf: Procedure Computertomographie [CT], nativ status: Final code: im kleinen Becken value: rückläufige KM-Aufnahme der lokalrezidivsuspekten Raumforderung
part of:
  l: PatientKimMusterperson-Procedure-5
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-5
status:
  v: final
code:
  coding: http://snomed.info/id/80266002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 80266002
    display:
      v: True pelvis
  text:
    v: im kleinen Becken
value: CodeableConcept
  coding: http://snomed.info/id/37865006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 37865006
    display:
      v: Regressive
  coding: http://snomed.info/id/385420005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 385420005
    display:
      v: Contrast media
  text:
    v: rückläufige KM-Aufnahme der lokalrezidivsuspekten Raumforderung

PatientKimMusterperson-Observation-22
type: Observation
id:
  v: PatientKimMusterperson-Observation-22
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-22 partOf: Procedure Computertomographie [CT], nativ status: Final code: zahlenmäßig vermehrten LK im Mediastinum value: noch flaue, aber insgesamt regrediente KM-Aufnhame
part of:
  l: PatientKimMusterperson-Procedure-5
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-5
status:
  v: final
code:
  coding: http://snomed.info/id/274744005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 274744005
    display:
      v: Localized enlarged lymph nodes
  text:
    v: zahlenmäßig vermehrten LK im Mediastinum
value: CodeableConcept
  coding: http://snomed.info/id/37865006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 37865006
    display:
      v: Regressive
  coding: http://snomed.info/id/385420005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 385420005
    display:
      v: Contrast media
  text:
    v: noch flaue, aber insgesamt regrediente KM-Aufnhame

PatientKimMusterperson-Observation-23
type: Observation
id:
  v: PatientKimMusterperson-Observation-23
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-23 partOf: Procedure Computertomographie [CT], nativ status: Final code: Läsion value: keine neue
part of:
  l: PatientKimMusterperson-Procedure-5
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-5
status:
  v: final
code:
  coding: http://snomed.info/id/52988006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 52988006
    display:
      v: Lesion
  text:
    v: Läsion
value: CodeableConcept
  coding: http://snomed.info/id/373067005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 373067005
    display:
      v: No
  text:
    v: keine neue

PatientKimMusterperson-Observation-24
type: Observation
id:
  v: PatientKimMusterperson-Observation-24
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-24 partOf: Procedure Computertomographie [CT], nativ status: Final code: Ascites value: kein Aszites
part of:
  l: PatientKimMusterperson-Procedure-6
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-6
status:
  v: final
code:
  coding: http://snomed.info/id/389026000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 389026000
    display:
      v: Ascites
value: CodeableConcept
  coding: http://snomed.info/id/860638000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 860638000
    display:
      v: No ascites
  text:
    v: kein Aszites

PatientKimMusterperson-Observation-25
type: Observation
id:
  v: PatientKimMusterperson-Observation-25
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-25 partOf: Procedure Computertomographie [CT], nativ status: Final code: Lokalrezidiv value: regredientes Lokalrezidiv ohne KM-Aufnahme im kleinen Becken
part of:
  l: PatientKimMusterperson-Procedure-6
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-6
status:
  v: final
code:
  coding: http://snomed.info/id/255227004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255227004
    display:
      v: Recurrent
  text:
    v: Lokalrezidiv
value: CodeableConcept
  coding: http://snomed.info/id/37865006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 37865006
    display:
      v: Regressive
  coding: http://snomed.info/id/373067005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 373067005
    display:
      v: No
  coding: http://snomed.info/id/385420005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 385420005
    display:
      v: Contrast media
  coding: http://snomed.info/id/151174005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 151174005
    display:
      v: Drug intake observed
  text:
    v: regredientes Lokalrezidiv ohne KM-Aufnahme im kleinen Becken

PatientKimMusterperson-Observation-26
type: Observation
id:
  v: PatientKimMusterperson-Observation-26
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-26 partOf: Procedure Computertomographie [CT], nativ status: Final code: kleinen Becken value: geringer Aszites
part of:
  l: PatientKimMusterperson-Procedure-7
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-7
status:
  v: final
code:
  coding: http://snomed.info/id/80266002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 80266002
    display:
      v: True pelvis
  text:
    v: kleinen Becken
value: CodeableConcept
  coding: http://snomed.info/id/255606000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 255606000
    display:
      v: Minor
  coding: http://snomed.info/id/389026000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 389026000
    display:
      v: Ascites
  text:
    v: geringer Aszites

PatientKimMusterperson-Observation-27
type: Observation
id:
  v: PatientKimMusterperson-Observation-27
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-27 partOf: Procedure Computertomographie [CT], nativ status: Final code: vormals KM-aufnehmendes Lokalrezidiv im kleinen Becken value: aktuell metrisch nur noch schwer fassbar bodySite: True pelvis
part of:
  l: PatientKimMusterperson-Procedure-7
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-7
status:
  v: final
code:
  coding: http://snomed.info/id/237679004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 237679004
    display:
      v: Status post (contextual qualifier) (qualifier value)
  coding: http://snomed.info/id/246455001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 246455001
    display:
      v: Recurrence
  text:
    v: vormals KM-aufnehmendes Lokalrezidiv im kleinen Becken
value: CodeableConcept
  coding: http://snomed.info/id/246455001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 246455001
    display:
      v: Recurrence
  coding: http://snomed.info/id/263920009
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 263920009
    display:
      v: Unrecordable
  text:
    v: aktuell metrisch nur noch schwer fassbar
body site:
  coding: http://snomed.info/id/80266002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 80266002
    display:
      v: True pelvis

PatientKimMusterperson-Observation-29
type: Observation
id:
  v: PatientKimMusterperson-Observation-29
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-29 partOf: Procedure Computertomographie [CT], nativ status: Final code: mediastinale Lymphknoten value: formal noch vermehrte
part of:
  l: PatientKimMusterperson-Procedure-7
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-7
status:
  v: final
code:
  coding: http://snomed.info/id/245276004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 245276004
    display:
      v: Mediastinal lymph node group
  text:
    v: mediastinale Lymphknoten
value: CodeableConcept
  coding: http://snomed.info/id/35105006
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 35105006
    display:
      v: Increased
  text:
    v: formal noch vermehrte

PatientKimMusterperson-Observation-30
type: Observation
id:
  v: PatientKimMusterperson-Observation-30
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation PatientKimMusterperson-Observation-30 partOf: Procedure Computertomographie [CT], nativ status: Final code: mediastinale Lymphknoten value: nicht mehr KM-aufnehmende
part of:
  l: PatientKimMusterperson-Procedure-7
  reference:
    v: Procedure/PatientKimMusterperson-Procedure-7
status:
  v: final
code:
  coding: http://snomed.info/id/245276004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 245276004
    display:
      v: Mediastinal lymph node group
  text:
    v: mediastinale Lymphknoten
value: CodeableConcept
  coding: http://snomed.info/id/373067005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 373067005
    display:
      v: No
  coding: http://snomed.info/id/385420005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 385420005
    display:
      v: Contrast media
  coding: http://snomed.info/id/151174005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 151174005
    display:
      v: Drug intake observed
  text:
    v: nicht mehr KM-aufnehmende

MII-EXA-MTB-Follow-Up-ClinicalImpression-1
type: ClinicalImpression
id:
  v: MII-EXA-MTB-Follow-Up-ClinicalImpression-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-follow-up-clinicalimpression|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-follow-up-clinicalimpression
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ClinicalImpression MII-EXA-MTB-Follow-Up-ClinicalImpression-1 Profile: MII PR MTB Clinical Impresssionversion: null2026.0.0) status: Completed code: Follow-up encounter (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-10-22 previous: ClinicalImpression: status = completed; effective[x] = 2023-01-20 --> 2023-03-28 Investigations - Code * completed supportingInfo: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie Claim: status = active; type = institutional; use = claim; created = 2023-03-10; priority = Normal ClaimResponse: status = active; type = institutional; use = claim; created = 2023-05-01; outcome = complete
status:
  v: completed
code:
  coding: http://snomed.info/id/390906007
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 390906007
    display:
      v: Follow-up encounter (procedure)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-10-22
previous:
  l: mii-exa-mtb-kim-musterperson-behandlungsepisode
  reference:
    v: ClinicalImpression/mii-exa-mtb-kim-musterperson-behandlungsepisode
investigation:
  code:
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-follow-up-status
        l: mii-cs-mtb-follow-up-status
      code:
        v: completed
supporting info:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
supporting info:
  l: MII-EXA-MTB-Antrag-Kostenuebernahme-1
  reference:
    v: Claim/MII-EXA-MTB-Antrag-Kostenuebernahme-1
supporting info:
  l: MII-EXA-MTB-Antwort-Kostenuebernahme-1
  reference:
    v: ClaimResponse/MII-EXA-MTB-Antwort-Kostenuebernahme-1

MII-EXA-MTB-Systemische-Therapie-1
type: Procedure
id:
  v: MII-EXA-MTB-Systemische-Therapie-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Procedure MII-EXA-MTB-Systemische-Therapie-1 Profile: MII PR MTB Systemische Therapieversion: null2026.0.0) MII EX Onko Systemische Therapie Intention: kurativ basedOn: CarePlan: status = active; intent = plan; category = prätherapeutische Tumorkonferenz (Festlegung der Therapiestrategie); created = 2023-03-28 status: Completed statusReason: regular-completion category: Chemotherapy (procedure) code: Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2023-06-24 --> 2023-10-12
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-systemische-therapie-intention
    l: mii-ex-onko-systemische-therapie-intention
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-intention
        l: mii-cs-onko-intention
      code:
        v: K
based on:
  l: mii-exa-mtb-kim-musterperson-therapieplan
  reference:
    v: CarePlan/mii-exa-mtb-kim-musterperson-therapieplan
status:
  v: completed
status reason:
  coding:
    code:
      v: regular-completion
category:
  coding: http://snomed.info/id/367336001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 367336001
    display:
      v: Chemotherapy (procedure)
code:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-typ
      l: mii-cs-onko-therapie-typ
    code:
      v: CH
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/ops
      l: ops
    version:
      v: 2023
    code:
      v: 8-54
    display:
      v: Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: Period
  start:
    v: 2023-06-24
  end:
    v: 2023-10-12

MII-EXA-MTB-Systemische-Therapie-Medication-1
type: MedicationStatement
id:
  v: MII-EXA-MTB-Systemische-Therapie-Medication-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemtherapie-medication-statement
    l: mii-pr-mtb-systemtherapie-medication-statement
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MII-EXA-MTB-Systemische-Therapie-Medication-1 Profiles: MII PR MTB Systemtherapie Medication Statement, https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0 basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-06-24 --> 2023-06-24 note: 24.06.2023 Z1 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-06-24
  end:
    v: 2023-06-24
note:
  text:
    v: 24.06.2023 Z1 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MII-EXA-MTB-Systemische-Therapie-Medication-2
type: MedicationStatement
id:
  v: MII-EXA-MTB-Systemische-Therapie-Medication-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemtherapie-medication-statement
    l: mii-pr-mtb-systemtherapie-medication-statement
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MII-EXA-MTB-Systemische-Therapie-Medication-2 Profiles: MII PR MTB Systemtherapie Medication Statement, https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0 basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Completed statusReason: E medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-07-16 --> 2023-07-16 note: 16.07.2023 Z2 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: completed
status reason:
  coding:
    code:
      v: E
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-07-16
  end:
    v: 2023-07-16
note:
  text:
    v: 16.07.2023 Z2 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MII-EXA-MTB-Systemische-Therapie-Medication-3
type: MedicationStatement
id:
  v: MII-EXA-MTB-Systemische-Therapie-Medication-3
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemtherapie-medication-statement
    l: mii-pr-mtb-systemtherapie-medication-statement
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MII-EXA-MTB-Systemische-Therapie-Medication-3 Profiles: MII PR MTB Systemtherapie Medication Statement, https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0 basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Completed statusReason: E medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-08-07 --> 2023-08-07 note: 07.08.2023 Z3 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: completed
status reason:
  coding:
    code:
      v: E
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-08-07
  end:
    v: 2023-08-07
note:
  text:
    v: 07.08.2023 Z3 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MII-EXA-MTB-Systemische-Therapie-Medication-4
type: MedicationStatement
id:
  v: MII-EXA-MTB-Systemische-Therapie-Medication-4
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemtherapie-medication-statement
    l: mii-pr-mtb-systemtherapie-medication-statement
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MII-EXA-MTB-Systemische-Therapie-Medication-4 Profiles: MII PR MTB Systemtherapie Medication Statement, https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0 basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-08-29 --> 2023-08-29 note: 29.08.2023 Z4 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-08-29
  end:
    v: 2023-08-29
note:
  text:
    v: 29.08.2023 Z4 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MII-EXA-MTB-Systemische-Therapie-Medication-5
type: MedicationStatement
id:
  v: MII-EXA-MTB-Systemische-Therapie-Medication-5
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemtherapie-medication-statement
    l: mii-pr-mtb-systemtherapie-medication-statement
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MII-EXA-MTB-Systemische-Therapie-Medication-5 Profiles: MII PR MTB Systemtherapie Medication Statement, https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0 basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Completed statusReason: E medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-09-20 --> 2023-09-20 note: 20.09.2023 Z2 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: completed
status reason:
  coding:
    code:
      v: E
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-09-20
  end:
    v: 2023-09-20
note:
  text:
    v: 20.09.2023 Z2 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MII-EXA-MTB-Systemische-Therapie-Medication-6
type: MedicationStatement
id:
  v: MII-EXA-MTB-Systemische-Therapie-Medication-6
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemtherapie-medication-statement
    l: mii-pr-mtb-systemtherapie-medication-statement
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MII-EXA-MTB-Systemische-Therapie-Medication-6 Profiles: MII PR MTB Systemtherapie Medication Statement, https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-therapie-medication-statement|2026.0.0 basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-10-12 --> 2023-10-12 note: 12.10.2023 Z3 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: Period
  start:
    v: 2023-10-12
  end:
    v: 2023-10-12
note:
  text:
    v: 12.10.2023 Z3 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MII-EXA-MTB-Response-Befund-1
type: Observation
id:
  v: MII-EXA-MTB-Response-Befund-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-response-befund|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-response-befund
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MII-EXA-MTB-Response-Befund-1 Profile: MII PR MTB Response Befundversion: null2026.0.0) partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Final code: Status of regression of tumor (observable entity) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 focus: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet effective: 2023-08-20 value: Complete Response method: RECIST Components - Code Value[x] * Presence of metastatic neoplasm in regional lymph node (observable entity) kein Lymphknotenbefall nachweisbar
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: final
code:
  coding: http://snomed.info/id/396432002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 396432002
    display:
      v: Status of regression of tumor (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
focus:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2
effective: DateTime
  v: 2023-08-20
value: CodeableConcept
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-response-befund-beurteilung
      l: mii-cs-mtb-response-befund-beurteilung
    code:
      v: CR
    display:
      v: Complete Response
method:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-response-befund-beurteilungsmethode
      l: mii-cs-mtb-response-befund-beurteilungsmethode
    code:
      v: RECIST
    display:
      v: RECIST
component:
  code:
    coding: http://snomed.info/id/399656008
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 399656008
      display:
        v: Presence of metastatic neoplasm in regional lymph node (observable entity)
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-verlauf-lymphknoten
        l: mii-cs-onko-verlauf-lymphknoten
      code:
        v: K
      display:
        v: kein Lymphknotenbefall nachweisbar

MII-EXA-MTB-Response-Befund-2
type: Observation
id:
  v: MII-EXA-MTB-Response-Befund-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-response-befund|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-response-befund
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation MII-EXA-MTB-Response-Befund-2 Profile: MII PR MTB Response Befundversion: null2026.0.0) partOf: Procedure Zytostatische Chemotherapie, Immuntherapie und antiretrovirale Therapie status: Final code: Status of regression of tumor (observable entity) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 focus: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet effective: 2023-10-22 value: Partial Response method: RECIST Components - Code Value[x] * Presence of metastatic neoplasm in regional lymph node (observable entity) kein Lymphknotenbefall nachweisbar
part of:
  l: MII-EXA-MTB-Systemische-Therapie-1
  reference:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
status:
  v: final
code:
  coding: http://snomed.info/id/396432002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 396432002
    display:
      v: Status of regression of tumor (observable entity)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
focus:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2
effective: DateTime
  v: 2023-10-22
value: CodeableConcept
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-response-befund-beurteilung
      l: mii-cs-mtb-response-befund-beurteilung
    code:
      v: PR
    display:
      v: Partial Response
method:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-response-befund-beurteilungsmethode
      l: mii-cs-mtb-response-befund-beurteilungsmethode
    code:
      v: RECIST
    display:
      v: RECIST
component:
  code:
    coding: http://snomed.info/id/399656008
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 399656008
      display:
        v: Presence of metastatic neoplasm in regional lymph node (observable entity)
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-verlauf-lymphknoten
        l: mii-cs-onko-verlauf-lymphknoten
      code:
        v: K
      display:
        v: kein Lymphknotenbefall nachweisbar

MII-EXA-MTB-Antrag-Kostenuebernahme-1
type: Claim
id:
  v: MII-EXA-MTB-Antrag-Kostenuebernahme-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-antrag-kostenuebernahme|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-antrag-kostenuebernahme
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Claim MII-EXA-MTB-Antrag-Kostenuebernahme-1 Profile: MII PR MTB Antrag Kostenuebernahmeversion: null2026.0.0) status: Active type: institutional use: Claim patient: Kim Musterperson (no stated gender), DoB: 1956-03-14 created: 2023-03-10 provider: Organization Example General Hospital priority: Normal Relateds - Relationship * initial-claim prescription: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 CareTeams - Sequence Provider Responsible * 1 Organization Example Health Insurance Co. true Insurances - Sequence Focal Coverage ClaimResponse * 1 true Coverage: status = active; type = extended healthcare; period = 2023-01-01 --> 2025-12-31 ClaimResponse: status = active; type = institutional; use = claim; created = 2023-05-01; outcome = complete
status:
  v: active
type:
  coding:
    code:
      v: institutional
use:
  v: claim
patient:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
created:
  v: 2023-03-10
provider:
  l: MyHospital
  reference:
    v: Organization/MyHospital
priority:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/processpriority
      l: processpriority
    code:
      v: normal
related:
  relationship:
    coding:
      code:
        v: initial-claim
prescription:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
care team:
  sequence:
    v: 1
  provider:
    l: MyInsurer
    reference:
      v: Organization/MyInsurer
  responsible:
    v: true
insurance:
  sequence:
    v: 1
  focal:
    v: true
  coverage:
    l: MyCoverage
    reference:
      v: Coverage/MyCoverage
  claim response:
    l: MII-EXA-MTB-Antwort-Kostenuebernahme-1
    reference:
      v: ClaimResponse/MII-EXA-MTB-Antwort-Kostenuebernahme-1

MII-EXA-MTB-Antwort-Kostenuebernahme-1
type: ClaimResponse
id:
  v: MII-EXA-MTB-Antwort-Kostenuebernahme-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-antwort-kostenuebernahme|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-antwort-kostenuebernahme
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ClaimResponse MII-EXA-MTB-Antwort-Kostenuebernahme-1 Profile: MII PR MTB Anwort Kostenuebernahmeversion: null2026.0.0) status: Active type: institutional use: Claim patient: Kim Musterperson (no stated gender), DoB: 1956-03-14 created: 2023-05-01 insurer: Organization Example General Hospital request: Claim: status = active; type = institutional; use = claim; created = 2023-03-10; priority = Normal outcome: Processing Complete
status:
  v: active
type:
  coding:
    code:
      v: institutional
use:
  v: claim
patient:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
created:
  v: 2023-05-01
insurer:
  l: MyHospital
  reference:
    v: Organization/MyHospital
request:
  l: MII-EXA-MTB-Antrag-Kostenuebernahme-1
  reference:
    v: Claim/MII-EXA-MTB-Antrag-Kostenuebernahme-1
outcome:
  v: complete

PatientKimMusterperson-Specimen-1
type: Specimen
id:
  v: PatientKimMusterperson-Specimen-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen
    l: mii-pr-patho-specimen
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Specimen PatientKimMusterperson-Specimen-1 Profile: MII PR Patho Specimen identifier: Z 230201/23 accessionIdentifier: Z 230201/23 status: Available type: Ascitic fluid specimen subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 Collections - Collected[x] Quantity Method * 2023-01-02 20 mL (Details: UCUM codemL = 'mL') 178012008
identifier:
  value:
    v: Z 230201/23
accession identifier:
  value:
    v: Z 230201/23
status:
  v: available
type:
  coding: http://snomed.info/id/309201001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 309201001
    display:
      v: Ascitic fluid specimen
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
collection:
  collected: DateTime
    v: 2023-01-02
  quantity:
    value:
      v: 20
    unit:
      v: mL
    system:
      v: http://unitsofmeasure.org
      l: unitsofmeasure.org
    code:
      v: mL
  method:
    coding: http://snomed.info/id/178012008
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 178012008

MTBChemo1Procedure
type: Procedure
id:
  v: MTBChemo1Procedure
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-vortherapie|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-vortherapie
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Procedure MTBChemo1Procedure Profile: MII PR MTB Systemische Vortherapieversion: null2026.0.0) MII EX Onko Systemische Therapie Intention: kurativ status: Completed category: 277132007 code: 367336001 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2023-01-04 --> 2023-05-24 outcome: Reguläres Ende mit Substanzwechsel
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-systemische-therapie-intention
    l: mii-ex-onko-systemische-therapie-intention
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-intention
        l: mii-cs-onko-intention
      code:
        v: K
status:
  v: completed
category:
  coding: http://snomed.info/id/277132007
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 277132007
code:
  coding: http://snomed.info/id/367336001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 367336001
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-typ
      l: mii-cs-onko-therapie-typ
    code:
      v: CH
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: Period
  start:
    v: 2023-01-04
  end:
    v: 2023-05-24
outcome:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-ende-grund
      l: mii-cs-onko-therapie-ende-grund
    code:
      v: W
  text:
    v: Reguläres Ende mit Substanzwechsel

MTBChemo1MedicationStatement1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement1 Profile: MII PR Medikation MedicationStatement partOf: Procedure 367336001 status: Completed medication: Z1 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-01-04
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
status:
  v: completed
medication: CodeableConcept
  text:
    v: Z1 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-01-04

MTBChemo1MedicationStatement1-1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement1-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement1-1 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-01-04 status: Completed medication: L01XA02 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-01-04 note: Z1 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 5 AUC (Details: UCUM codemg.min/ml = 'mg.min/ml')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement1
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01XA02
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-01-04
note:
  text:
    v: Z1 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 5
      unit:
        v: AUC
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg.min/ml

MTBChemo1MedicationStatement1-2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement1-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement1-2 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-01-04 status: Completed medication: L01DB01 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-01-04 note: Z1 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 30 mg/m2 (Details: UCUM codemg/m2 = 'mg/m2')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement1
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01DB01
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-01-04
note:
  text:
    v: Z1 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 30
      unit:
        v: mg/m2
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/m2

MTBChemo1MedicationStatement2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement2 Profile: MII PR Medikation MedicationStatement partOf: Procedure 367336001 status: Completed medication: Z2 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-02-01
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
status:
  v: completed
medication: CodeableConcept
  text:
    v: Z2 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-02-01

MTBChemo1MedicationStatement2-1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement2-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement2-1 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-02-01 status: Completed medication: L01XA02 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-02-01 note: Z2 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 5 AUC (Details: UCUM codemg.min/ml = 'mg.min/ml')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement2
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01XA02
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-02-01
note:
  text:
    v: Z2 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 5
      unit:
        v: AUC
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg.min/ml

MTBChemo1MedicationStatement2-2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement2-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement2-2 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-02-01 status: Completed medication: L01DB01 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-02-01 note: Z2 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 30 mg/m2 (Details: UCUM codemg/m2 = 'mg/m2')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement2
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01DB01
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-02-01
note:
  text:
    v: Z2 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 30
      unit:
        v: mg/m2
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/m2

MTBChemo1MedicationStatement3
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement3
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement3 Profile: MII PR Medikation MedicationStatement partOf: Procedure 367336001 status: Completed medication: Z3 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-01
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
status:
  v: completed
medication: CodeableConcept
  text:
    v: Z3 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-01

MTBChemo1MedicationStatement3-1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement3-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement3-1 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-03-01 status: Completed medication: L01XA02 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-01 note: Z3 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 5 AUC (Details: UCUM codemg.min/ml = 'mg.min/ml')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement3
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01XA02
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-01
note:
  text:
    v: Z3 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 5
      unit:
        v: AUC
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg.min/ml

MTBChemo1MedicationStatement3-2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement3-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement3-2 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-03-01 status: Completed medication: L01DB01 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-01 note: Z3 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 30 mg/m2 (Details: UCUM codemg/m2 = 'mg/m2')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement3
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01DB01
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-01
note:
  text:
    v: Z3 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 30
      unit:
        v: mg/m2
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/m2

MTBChemo1MedicationStatement4
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement4
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement4 Profile: MII PR Medikation MedicationStatement partOf: Procedure 367336001 status: Completed medication: Z4 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-29
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
status:
  v: completed
medication: CodeableConcept
  text:
    v: Z4 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-29

MTBChemo1MedicationStatement4-1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement4-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement4-1 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-03-29 status: Completed medication: L01XA02 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-29 note: Z4 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 5 AUC (Details: UCUM codemg.min/ml = 'mg.min/ml')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement4
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01XA02
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-29
note:
  text:
    v: Z4 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 5
      unit:
        v: AUC
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg.min/ml

MTBChemo1MedicationStatement4-2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement4-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement4-2 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-03-29 status: Completed medication: L01DB01 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-03-29 note: Z4 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 30 mg/m2 (Details: UCUM codemg/m2 = 'mg/m2')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement4
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01DB01
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-03-29
note:
  text:
    v: Z4 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 30
      unit:
        v: mg/m2
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/m2

MTBChemo1MedicationStatement5
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement5
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement5 Profile: MII PR Medikation MedicationStatement partOf: Procedure 367336001 status: Completed medication: Z5 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-04-26
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
status:
  v: completed
medication: CodeableConcept
  text:
    v: Z5 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-04-26

MTBChemo1MedicationStatement5-1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement5-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement5-1 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-04-26 status: Completed medication: L01XA02 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-04-26 note: Z5 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 5 AUC (Details: UCUM codemg.min/ml = 'mg.min/ml')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement5
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01XA02
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-04-26
note:
  text:
    v: Z5 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 5
      unit:
        v: AUC
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg.min/ml

MTBChemo1MedicationStatement5-2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement5-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement5-2 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-04-26 status: Completed medication: L01DB01 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-04-26 note: Z5 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 30 mg/m2 (Details: UCUM codemg/m2 = 'mg/m2')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement5
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01DB01
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-04-26
note:
  text:
    v: Z5 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 30
      unit:
        v: mg/m2
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/m2

MTBChemo1MedicationStatement6
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement6
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement6 Profile: MII PR Medikation MedicationStatement partOf: Procedure 367336001 status: Completed medication: Z6 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-05-24
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
status:
  v: completed
medication: CodeableConcept
  text:
    v: Z6 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2, d1
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-05-24

MTBChemo1MedicationStatement6-1
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement6-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement6-1 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-05-24 status: Completed medication: L01XA02 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-05-24 note: Z6 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 5 AUC (Details: UCUM codemg.min/ml = 'mg.min/ml')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement6
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01XA02
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-05-24
note:
  text:
    v: Z6 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 5
      unit:
        v: AUC
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg.min/ml

MTBChemo1MedicationStatement6-2
type: MedicationStatement
id:
  v: MTBChemo1MedicationStatement6-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-systemische-therapie-medikation
    l: mii-pr-onko-systemische-therapie-medikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo1MedicationStatement6-2 Profile: MII PR Onkologie Systemische Therapie Medikation partOf: Procedure 367336001 MedicationStatement: status = completed; medication[x] = ; effective[x] = 2023-05-24 status: Completed medication: L01DB01 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-05-24 note: Z6 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1 dosage DoseAndRates - Dose[x] * 30 mg/m2 (Details: UCUM codemg/m2 = 'mg/m2')
part of:
  l: MTBChemo1Procedure
  reference:
    v: Procedure/MTBChemo1Procedure
part of:
  l: MTBChemo1MedicationStatement6
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    code:
      v: L01DB01
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-05-24
note:
  text:
    v: Z6 Carboplatin AUC5 d1, pegliposomales Doxorubicin 30 mg/m2 d1
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 30
      unit:
        v: mg/m2
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/m2

MTBChemo2Procedure
type: Procedure
id:
  v: MTBChemo2Procedure
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-vortherapie|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-systemische-vortherapie
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Procedure MTBChemo2Procedure Profile: MII PR MTB Systemische Vortherapieversion: null2026.0.0) MII EX Onko Systemische Therapie Intention: kurativ basedOn: CarePlan: status = active; intent = plan; category = prätherapeutische Tumorkonferenz (Festlegung der Therapiestrategie); created = 2023-03-28 status: Completed category: 277132007 code: 367336001 subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 performed: 2023-06-24 --> 2023-10-12 outcome: Reguläres Ende
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-systemische-therapie-intention
    l: mii-ex-onko-systemische-therapie-intention
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-intention
        l: mii-cs-onko-intention
      code:
        v: K
based on:
  l: mii-exa-mtb-kim-musterperson-therapieplan
  reference:
    v: CarePlan/mii-exa-mtb-kim-musterperson-therapieplan
status:
  v: completed
category:
  coding: http://snomed.info/id/277132007
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 277132007
code:
  coding: http://snomed.info/id/367336001
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 367336001
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-typ
      l: mii-cs-onko-therapie-typ
    code:
      v: CH
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
performed: Period
  start:
    v: 2023-06-24
  end:
    v: 2023-10-12
outcome:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-ende-grund
      l: mii-cs-onko-therapie-ende-grund
    code:
      v: E
  text:
    v: Reguläres Ende

MTBChemo2MedicationStatement1
type: MedicationStatement
id:
  v: MTBChemo2MedicationStatement1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo2MedicationStatement1 Profile: MII PR Medikation MedicationStatement basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure 367336001 status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-06-24 note: Z1 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MTBChemo2Procedure
  reference:
    v: Procedure/MTBChemo2Procedure
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-06-24
note:
  text:
    v: Z1 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MTBChemo2MedicationStatement2
type: MedicationStatement
id:
  v: MTBChemo2MedicationStatement2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo2MedicationStatement2 Profile: MII PR Medikation MedicationStatement basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure 367336001 status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-07-16 note: Z2 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MTBChemo2Procedure
  reference:
    v: Procedure/MTBChemo2Procedure
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-07-16
note:
  text:
    v: Z2 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MTBChemo2MedicationStatement3
type: MedicationStatement
id:
  v: MTBChemo2MedicationStatement3
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo2MedicationStatement3 Profile: MII PR Medikation MedicationStatement basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure 367336001 status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-08-07 note: Z3 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MTBChemo2Procedure
  reference:
    v: Procedure/MTBChemo2Procedure
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-08-07
note:
  text:
    v: Z3 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MTBChemo2MedicationStatement4
type: MedicationStatement
id:
  v: MTBChemo2MedicationStatement4
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo2MedicationStatement4 Profile: MII PR Medikation MedicationStatement basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure 367336001 status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-08-29 note: Z4 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MTBChemo2Procedure
  reference:
    v: Procedure/MTBChemo2Procedure
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-08-29
note:
  text:
    v: Z4 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MTBChemo2MedicationStatement5
type: MedicationStatement
id:
  v: MTBChemo2MedicationStatement5
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo2MedicationStatement5 Profile: MII PR Medikation MedicationStatement basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure 367336001 status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-09-20 note: Z5 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MTBChemo2Procedure
  reference:
    v: Procedure/MTBChemo2Procedure
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-09-20
note:
  text:
    v: Z5 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

MTBChemo2MedicationStatement6
type: MedicationStatement
id:
  v: MTBChemo2MedicationStatement6
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/core/modul-medikation/StructureDefinition/MedicationStatement
    l: MedicationStatement
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationStatement MTBChemo2MedicationStatement6 Profile: MII PR Medikation MedicationStatement basedOn: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 partOf: Procedure 367336001 status: Completed medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 effective: 2023-10-12 note: Z6 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22 dosage DoseAndRates - Dose[x] * 6 mg/kg KG (Details: UCUM codemg/kg{KG} = 'mg/kg{KG}')
based on:
  l: mii-exa-mtb-medication-request-mirvetuximab
  reference:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
part of:
  l: MTBChemo2Procedure
  reference:
    v: Procedure/MTBChemo2Procedure
status:
  v: completed
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
effective: DateTime
  v: 2023-10-12
note:
  text:
    v: Z6 Mirvetuximab soravtansine 6mg/kg KG, Wdh d22
dosage:
  dose and rate:
    dose: Quantity
      value:
        v: 6
      unit:
        v: mg/kg KG
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: mg/kg{KG}

mii-exa-mtb-kim-musterperson-ngs-bericht
type: DiagnosticReport
id:
  v: mii-exa-mtb-kim-musterperson-ngs-bericht
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-ngs-bericht|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-ngs-bericht
text:
  status:
    v: generated
  div:
    v: Generated Narrative: DiagnosticReport mii-exa-mtb-kim-musterperson-ngs-bericht Profile: MII PR MTB NGS-Berichtversion: null2026.0.0) Genetic analysis report (Genetics) Subject Kim Musterperson (no stated gender), DoB: 1956-03-14 Reported 2023-03-28 00:00:00+0000 Report Details Code Value Flags Genetic variant assessment Present Final Genetic variant assessment Present Final Genetic variant assessment Present Final
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
    display:
      v: Genetics
code:
  coding: https://loinc.org/rdf/51969-4
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 51969-4
    display:
      v: Genetic analysis report
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
issued:
  v: 2023-03-28T00:00:00.000Z
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2
result:
  l: mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
  reference:
    v: Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
result:
  l: mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
  reference:
    v: Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
result:
  l: mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
  reference:
    v: Observation/mii-exa-mtb-kim-musterperson-CNVariante-CCNE1

mii-exa-mtb-kim-musterperson-genomic-study
type: Procedure
id:
  v: mii-exa-mtb-kim-musterperson-genomic-study
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Procedure mii-exa-mtb-kim-musterperson-genomic-study Profile: MII PR MTB Genomic Studyversion: null2026.0.0) Genomic Study Analysis Extension: Procedure: extension = Next-Generation (NGS)/Massively parallel sequencing (MPS),SNV,SNV,GRCh38; status = completed; category = Labor Genomic Study Analysis Extension: Procedure: status = completed; category = Labor Genomic Study Analysis Extension: Procedure: extension = Immunohistochemistry; status = completed; category = Labor status: Completed category: Labor subject: Kim Musterperson (no stated gender), DoB: 1956-03-14
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-ext
    l: genomic-study-analysis-ext
  value: Reference
    l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
    reference:
      v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-ext
    l: genomic-study-analysis-ext
  value: Reference
    l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
    reference:
      v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-ext
    l: genomic-study-analysis-ext
  value: Reference
    l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
    reference:
      v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
status:
  v: completed
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson

mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
type: Procedure
id:
  v: mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study-analysis|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study-analysis
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Procedure mii-exa-mtb-kim-musterperson-genomic-study-analysis-1 Profile: MII PR MTB Genomic Study Analysisversion: null2026.0.0) Genomic Study Analysis Method Type: Next-Generation (NGS)/Massively parallel sequencing (MPS) Genomic Study Analysis Change Type: SNV Genomic Study Analysis Genome Build: GRCh38 status: Completed category: Labor subject: Kim Musterperson (no stated gender), DoB: 1956-03-14
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-method-type
    l: genomic-study-analysis-method-type
  value: CodeableConcept
    coding:
      system:
        v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/genomic-study-method-type-cs
        l: genomic-study-method-type-cs
      code:
        v: ngs-mps
      display:
        v: Next-Generation (NGS)/Massively parallel sequencing (MPS)
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-change-type
    l: genomic-study-analysis-change-type
  value: CodeableConcept
    coding:
      system:
        v: http://www.sequenceontology.org
        l: www.sequenceontology.org
      code:
        v: SO:0001483
      display:
        v: SNV
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-genome-build
    l: genomic-study-analysis-genome-build
  value: CodeableConcept
    coding: LA26806-2
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: LA26806-2
      display:
        v: GRCh38
status:
  v: completed
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson

mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
type: Procedure
id:
  v: mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study-analysis|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study-analysis
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Procedure mii-exa-mtb-kim-musterperson-genomic-study-analysis-2 Profile: MII PR MTB Genomic Study Analysisversion: null2026.0.0) status: Completed category: Labor subject: Kim Musterperson (no stated gender), DoB: 1956-03-14
status:
  v: completed
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson

mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
type: Procedure
id:
  v: mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study-analysis|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-genomic-study-analysis
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Procedure mii-exa-mtb-kim-musterperson-genomic-study-analysis-3 Profile: MII PR MTB Genomic Study Analysisversion: null2026.0.0) Genomic Study Analysis Method Type: Immunohistochemistry status: Completed category: Labor subject: Kim Musterperson (no stated gender), DoB: 1956-03-14
extension:
  url:
    v: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/genomic-study-analysis-method-type
    l: genomic-study-analysis-method-type
  value: CodeableConcept
    coding:
      system:
        v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/genomic-study-method-type-cs
        l: genomic-study-method-type-cs
      code:
        v: immunohistochemistry
      display:
        v: Immunohistochemistry
status:
  v: completed
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson

mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
type: Observation
id:
  v: mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-einfache-variante|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-einfache-variante
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53 Profile: MII PR MTB Einfache Varianteversion: null2026.0.0) status: Final category: Laboratory, Genetik code: Genetic variant assessment subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Present component code: Gene studied [ID] value: TP53 component code: Amino acid change (pHGVS) value: NP_000537.3:p.Arg213Ter
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
    display:
      v: Laboratory
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
code:
  coding: https://loinc.org/rdf/69548-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 69548-6
    display:
      v: Genetic variant assessment
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA9633-4
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA9633-4
    display:
      v: Present
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:11998
      display:
        v: TP53
component:
  code:
    coding: https://loinc.org/rdf/48005-3
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48005-3
      display:
        v: Amino acid change (pHGVS)
  value: CodeableConcept
    coding:
      system:
        v: http://varnomen.hgvs.org
        l: varnomen.hgvs.org
      code:
        v: NP_000537.3:p.Arg213Ter

mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53
type: Observation
id:
  v: mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-diagnostische-implikation|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-diagnostische-implikation
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53 Profile: MII PR MTB Diagnostische Implikationversion: null2026.0.0) status: Final category: Laboratory, Genetik code: Diagnostic Implication subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 derivedFrom: Observation Genetic variant assessment Components - Code Value[x] * Genetic variation clinical significance [Imp] Pathogenic
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
    display:
      v: Laboratory
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
code:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: diagnostic-implication
    display:
      v: Diagnostic Implication
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
derived from:
  l: mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
  reference:
    v: Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
component:
  code:
    coding: https://loinc.org/rdf/53037-8
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 53037-8
  value: CodeableConcept
    coding: LA6668-3
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: LA6668-3
      display:
        v: Pathogenic

mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
type: Observation
id:
  v: mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-einfache-variante|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-einfache-variante
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1 Profile: MII PR MTB Einfache Varianteversion: null2026.0.0) status: Final category: Laboratory, Genetik code: Genetic variant assessment subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Present component code: Gene studied [ID] value: PIK3R1 component code: Amino acid change (pHGVS) value: NM_181523.2:p.E160*
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
    display:
      v: Laboratory
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
code:
  coding: https://loinc.org/rdf/69548-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 69548-6
    display:
      v: Genetic variant assessment
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA9633-4
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA9633-4
    display:
      v: Present
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:8979
      display:
        v: PIK3R1
component:
  code:
    coding: https://loinc.org/rdf/48005-3
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48005-3
      display:
        v: Amino acid change (pHGVS)
  value: CodeableConcept
    coding:
      system:
        v: http://varnomen.hgvs.org
        l: varnomen.hgvs.org
      code:
        v: NM_181523.2:p.E160*

mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1
type: Observation
id:
  v: mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapeutische-implikation|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapeutische-implikation
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1 Profile: MII PR MTB Therapeutische Implikationversion: null2026.0.0) MII EX MTB Empfehlung Evidenzgraduierung: m3 status: Final category: Laboratory, Genetik code: Therapeutic Implication subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 derivedFrom: Observation Genetic variant assessment component code: Conclusion Text value: Ausweislich praeklinischer Daten liegt ein Ansprechen auf MEK-Inhibition nahe (PMID: 31209687, EL m3). component code: Medication assessed [ID] value: Mitogen-aktivierte Proteinkinase (MEK)-Inhibitoren
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-evidenzgraduierung
    l: mii-ex-mtb-empfehlung-evidenzgraduierung
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-empfehlung-evidenzgrad
        l: mii-cs-mtb-empfehlung-evidenzgrad
      code:
        v: m3
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
    display:
      v: Laboratory
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
code:
  coding:
    system:
      v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
      l: tbd-codes-cs
    code:
      v: therapeutic-implication
    display:
      v: Therapeutic Implication
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
derived from:
  l: mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
  reference:
    v: Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
component:
  code:
    coding:
      system:
        v: http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
        l: tbd-codes-cs
      code:
        v: conclusion-string
  value: String
    v: Ausweislich praeklinischer Daten liegt ein Ansprechen auf MEK-Inhibition nahe (PMID: 31209687, EL m3).
component:
  code:
    coding: https://loinc.org/rdf/51963-7
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 51963-7
      display:
        v: Medication assessed [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://fhir.de/CodeSystem/bfarm/atc
        l: atc
      code:
        v: L01EE
      display:
        v: Mitogen-aktivierte Proteinkinase (MEK)-Inhibitoren

mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
type: Observation
id:
  v: mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-copy-number-variant|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-copy-number-variant
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-musterperson-CNVariante-CCNE1 Profile: MII PR MTB Copy Number Variantversion: null2026.0.0) status: Final category: Laboratory, Genetik code: Genetic variant assessment subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 value: Present component code: Gene studied [ID] value: CCNE1 component code: type value: high-level-gain component code: Genomic structural variant copy number value: 7 1 (Details: UCUM code1 = '1')
status:
  v: final
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/observation-category
      l: observation-category
    code:
      v: laboratory
    display:
      v: Laboratory
category:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/v2-0074
      l: v2-0074
    code:
      v: GE
code:
  coding: https://loinc.org/rdf/69548-6
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 69548-6
    display:
      v: Genetic variant assessment
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
value: CodeableConcept
  coding: LA9633-4
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: LA9633-4
    display:
      v: Present
component:
  code:
    coding: https://loinc.org/rdf/48018-6
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 48018-6
      display:
        v: Gene studied [ID]
  value: CodeableConcept
    coding:
      system:
        v: http://www.genenames.org/geneId
        l: geneId
      code:
        v: HGNC:1589
      display:
        v: CCNE1
component:
  code:
    coding:
      system:
        v: http://bwhc.de/mtb/genetics-copy-number-variant
        l: genetics-copy-number-variant
      code:
        v: type
  value: CodeableConcept
    coding:
      system:
        v: http://bwhc.de/mtb/genetics-copy-number-variant
        l: genetics-copy-number-variant
      code:
        v: high-level-gain
      display:
        v: high-level-gain
component:
  code:
    coding: https://loinc.org/rdf/82155-3
      system:
        v: http://loinc.org
        l: loinc.org
      code:
        v: 82155-3
      display:
        v: Genomic structural variant copy number
  value: Quantity
    value:
      v: 7
    system:
      v: http://unitsofmeasure.org
      l: unitsofmeasure.org
    code:
      v: 1

mii-exa-mtb-study-request-cldn6
type: ServiceRequest
id:
  v: mii-exa-mtb-study-request-cldn6
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studieneinschluss-anfrage|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studieneinschluss-anfrage
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: ServiceRequest mii-exa-mtb-study-request-cldn6 Profile: MII PR MTB Studieneinschluss Anfrageversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 2.1 MII EX MTB Empfehlung Publikation: http://www.ncbi.nlm.nih.gov/pubmed/37872225 status: Draft intent: Proposal category: Clinical trial (procedure) code: Referral to clinical trial (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 supportingInfo: ResearchStudy: identifier = https://www.medizininformatik-initiative.de/fhir/modul-mtb/sid/nct#MII_NS_MTB_NCT#04503278; status = active; primaryPurposeType = treatment; phase = phase-1; condition = Solid tumor configuration; keyword = ; period = 2020-09-16 --> 2040-01
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: Decimal
    v: 2.1
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://www.ncbi.nlm.nih.gov/pubmed
      l: pubmed
    value:
      v: 37872225
status:
  v: draft
intent:
  v: proposal
category:
  coding: http://snomed.info/id/110465008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 110465008
    display:
      v: Clinical trial (procedure)
code:
  coding: http://snomed.info/id/702475000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 702475000
    display:
      v: Referral to clinical trial (procedure)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
supporting info:
  l: mii-exa-mtb-study-cldn6
  reference:
    v: ResearchStudy/mii-exa-mtb-study-cldn6

mii-exa-mtb-study-cldn6
type: ResearchStudy
id:
  v: mii-exa-mtb-study-cldn6
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studie|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studie
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ResearchStudy mii-exa-mtb-study-cldn6 Profile: MII PR MTB Studieversion: null2026.0.0) identifier: MII_NS_MTB_NCT/04503278 status: Active primaryPurposeType: treatment phase: phase-1 condition: Solid tumor configuration keyword: Non-small cell lung cancer (NSCLC) enrollment: Group: type = person; actual = false; quantity = 145 period: 2020-09-16 --> 2040-01 sponsor: Organization BioNTech Cell & Gene Therapies GmbH principalInvestigator: PractitionerRole Study coordinator site: Location Karolinska Comprehensive Cancer Center Cancerstudieenheten Huddinge Karolinska Universitetssjukhuset arm name: Part 1 - CLDN6 CAR-T: Dose escalation in lymphodepleted patients until the MTD and/or RP2D arm name: Part 2 Vaccine-modulated - CLDN6 uRNA-LPX/CLDN6 modRNA-LPX: Dose escalation until the MTD and/or RP2D objective name: Occurrence of treatment-emergent adverse events (TEAEs) including ≥ Grade 3, serious, fatal TEAEs by relationship type: primary objective name: Occurrence of dose reduction and discontinuation of investigational medicinal product (IMP) due to TEAEs type: primary objective name: Occurrence of dose-limiting toxicity (DLT) during the DLT evaluation period type: primary objective name: Change from baseline in the levels and kinetics of soluble immune factors measured by cytokine multiplex assay type: secondary objective name: Objective response rate (ORR) defined as the proportion of patients in whom a complete response (CR) or partial response (PR) (per response evaluation criteria in solid tumors [RECIST 1.1]) is observed as best overall response type: secondary objective name: Disease control rate (DCR) defined as the proportion of patients in whom a CR or PR or stable disease (SD) (per RECIST 1.1, SD assessed at least 6 weeks after the first dose) is observed as best overall response type: secondary objective name: Duration of response (DOR) defined as the time from first objective response (CR or PR per RECIST 1.1) to first occurrence of o…
identifier:
  system:
    v: https://www.medizininformatik-initiative.de/fhir/modul-mtb/sid/nct
    l: nct
  value:
    v: 04503278
status:
  v: active
primary purpose type:
  coding:
    code:
      v: treatment
phase:
  coding:
    code:
      v: phase-1
condition:
  coding: http://snomed.info/id/369757002
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 369757002
    display:
      v: Solid tumor configuration
keyword:
  text:
    v: Non-small cell lung cancer (NSCLC)
enrollment:
  l: mii-exa-mtb-study-cldn6-eligibility-criteria
  reference:
    v: Group/mii-exa-mtb-study-cldn6-eligibility-criteria
period:
  start:
    v: 2020-09-16
  end:
    v: 2040-01
sponsor:
  l: mii-exa-mtb-study-sponsor-biontech
  reference:
    v: Organization/mii-exa-mtb-study-sponsor-biontech
principal investigator:
  l: mii-exa-mtb-study-investigator-biontech
  reference:
    v: PractitionerRole/mii-exa-mtb-study-investigator-biontech
site:
  l: mii-exa-mtb-study-cldn6-location-11
  reference:
    v: Location/mii-exa-mtb-study-cldn6-location-11
arm:
  name:
    v: Part 1 - CLDN6 CAR-T: Dose escalation in lymphodepleted patients until the MTD and/or RP2D
arm:
  name:
    v: Part 2 Vaccine-modulated - CLDN6 uRNA-LPX/CLDN6 modRNA-LPX: Dose escalation until the MTD and/or RP2D
objective:
  name:
    v: Occurrence of treatment-emergent adverse events (TEAEs) including ≥ Grade 3, serious, fatal TEAEs by relationship
  type:
    coding:
      code:
        v: primary
objective:
  name:
    v: Occurrence of dose reduction and discontinuation of investigational medicinal product (IMP) due to TEAEs
  type:
    coding:
      code:
        v: primary
objective:
  name:
    v: Occurrence of dose-limiting toxicity (DLT) during the DLT evaluation period
  type:
    coding:
      code:
        v: primary
objective:
  name:
    v: Change from baseline in the levels and kinetics of soluble immune factors measured by cytokine multiplex assay
  type:
    coding:
      code:
        v: secondary
objective:
  name:
    v: Objective response rate (ORR) defined as the proportion of patients in whom a complete response (CR) or partial response (PR) (per response evaluation criteria in solid tumors [RECIST 1.1]) is observed as best overall response
  type:
    coding:
      code:
        v: secondary
objective:
  name:
    v: Disease control rate (DCR) defined as the proportion of patients in whom a CR or PR or stable disease (SD) (per RECIST 1.1, SD assessed at least 6 weeks after the first dose) is observed as best overall response
  type:
    coding:
      code:
        v: secondary
objective:
  name:
    v: Duration of response (DOR) defined as the time from first objective response (CR or PR per RECIST 1.1) to first occurrence of objective progressive disease (PD) per RECIST 1.1/recurrence or death from any cause, whichever occurs first
  type:
    coding:
      code:
        v: secondary

mii-exa-mtb-study-cldn6-eligibility-criteria
type: Group
id:
  v: mii-exa-mtb-study-cldn6-eligibility-criteria
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Group mii-exa-mtb-study-cldn6-eligibility-criteria type: Person actual: false quantity: 145 characteristic code: Eligibility Criteria value: Inclusion Criteria: * Each patient enrolled in the trial must have CLDN6-positive tumor regardless of tumor histology defined as ≥ 50% of tumor cells expressing ≥ 2+ CLDN6 protein using a semi-quantitative immunohistochemistry (IHC) assay in a central laboratory for specific detection of CLDN6 protein expression in formalin-fixed, paraffin-embedded (FFPE) neoplastic tissues. * Availability of a FFPE tumor tissue sample. FFPE can be from an archival tumor tissue sample, and it should be from the most recent tumor tissue obtained. If this is not available, patient must be biopsied for CLDN6 staining. * Must have histological documentation of the original primary tumor via a pathology report. * Must have measurable disease per RECIST 1.1 (except for germ cell tumors, where patients can be evaluated according to Cancer-Antigen (CA)-125, Alpha-fetoprotein or human chorionic gonadotropin \[as applicable\] or ovarian cancer, where patients can be evaluated according to CA-125. The pre-treatment sample must be at least twice the upper limit of normal). * Must have a histologically confirmed solid tumor that is metastatic or unresectable and for which there is no available standard therapy likely to confer clinical benefit, or patient who is not a candidate for such available therapy. * Must be ≥ 18 years of age at the time the pre-screening informed consent is signed. * Must sign an informed consent form (ICF) indicating that he or she understands the purpose of and procedures required for the trial and are willing to participate in the trial prior to any trial-related assessments or procedures. * Must have an Eastern Cooperative Oncology Group performance status of 0 to 1. * Must have adequate coagulation function at screening as defined in the protocol. * Must have adequate hematologic function at screening as de…
type:
  v: person
actual:
  v: false
quantity:
  v: 145
characteristic:
  code:
    text:
      v: Eligibility Criteria
  value: Reference
    display:
      v: Inclusion Criteria: * Each patient enrolled in the trial must have CLDN6-positive tumor regardless of tumor histology defined as ≥ 50% of tumor cells expressing ≥ 2+ CLDN6 protein using a semi-quantitative immunohistochemistry (IHC) assay in a central laboratory for specific detection of CLDN6 protein expression in formalin-fixed, paraffin-embedded (FFPE) neoplastic tissues. * Availability of a FFPE tumor tissue sample. FFPE can be from an archival tumor tissue sample, and it should be from the most recent tumor tissue obtained. If this is not available, patient must be biopsied for CLDN6 staining. * Must have histological documentation of the original primary tumor via a pathology report. * Must have measurable disease per RECIST 1.1 (except for germ cell tumors, where patients can be evaluated according to Cancer-Antigen (CA)-125, Alpha-fetoprotein or human chorionic gonadotropin \[as applicable\] or ovarian cancer, where patients can be evaluated according to CA-125. The pre-treatment sample must be at least twice the upper limit of normal). * Must have a histologically confirmed solid tumor that is metastatic or unresectable and for which there is no available standard therapy likely to confer clinical benefit, or patient who is not a candidate for such available therapy. * Must be ≥ 18 years of age at the time the pre-screening informed consent is signed. * Must sign an informed consent form (ICF) indicating that he or she understands the purpose of and procedures required for the trial and are willing to participate in the trial prior to any trial-related assessments or procedures. * Must have an Eastern Cooperative Oncology Group performance status of 0 to 1. * Must have adequate coagulation function at screening as defined in the protocol. * Must have adequate hematologic function at screening as defined in the protocol. * Must have adequate hepatic function at screening as defined in the protocol. * Must have adequate renal function at screening as defined …
  exclude:
    v: false
characteristic:
  code:
    text:
      v: Accepts Healthy Volunteers
  value: Boolean
    v: false
  exclude:
    v: false
characteristic:
  code:
    text:
      v: Age
  value: Range
    low:
      value:
        v: 18
      unit:
        v: year
      system:
        v: http://unitsofmeasure.org
        l: unitsofmeasure.org
      code:
        v: a
  exclude:
    v: false
characteristic:
  code:
    text:
      v: Age Group
  value: Reference
    l: mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
    reference:
      v: Group/mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
  exclude:
    v: false

mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
type: Group
id:
  v: mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Group mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups type: Person actual: false characteristic code: Age Group (Adult) value: Adulthood (qualifier value) exclude: false characteristic code: Age Group (Older Adult) value: Old age (qualifier value) exclude: false
type:
  v: person
actual:
  v: false
characteristic:
  code:
    text:
      v: Age Group (Adult)
  value: CodeableConcept
    coding: http://snomed.info/id/41847000
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 41847000
      display:
        v: Adulthood (qualifier value)
  exclude:
    v: false
characteristic:
  code:
    text:
      v: Age Group (Older Adult)
  value: CodeableConcept
    coding: http://snomed.info/id/271872005
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 271872005
      display:
        v: Old age (qualifier value)
  exclude:
    v: false

mii-exa-mtb-study-cldn6-comparison-group-0
type: Group
id:
  v: mii-exa-mtb-study-cldn6-comparison-group-0
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Group mii-exa-mtb-study-cldn6-comparison-group-0 type: Person actual: false Characteristics - Code Value[x] Exclude * Exposed to Biological: CLDN6 CAR-T false
type:
  v: person
actual:
  v: false
characteristic:
  code:
    text:
      v: Exposed to
  value: Reference
    l: mii-exa-mtb-study-cldn6-evidence-variable-0
    reference:
      v: EvidenceVariable/mii-exa-mtb-study-cldn6-evidence-variable-0
    display:
      v: Biological: CLDN6 CAR-T
  exclude:
    v: false

mii-exa-mtb-study-cldn6-evidence-variable-0
type: EvidenceVariable
id:
  v: mii-exa-mtb-study-cldn6-evidence-variable-0
text:
  status:
    v: generated
  div:
    v: Generated Narrative: EvidenceVariable mii-exa-mtb-study-cldn6-evidence-variable-0 status: Active UseContexts - Code Value[x] * SNOMED CT: 362956003 (Procedure/intervention (navigational concept)) Biological Characteristics - Definition[x] * Group: type = person; actual = false; quantity = 145
status:
  v: active
use context:
  code: http://snomed.info/id/362956003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 362956003
    display:
      v: Procedure/intervention (navigational concept)
  value: CodeableConcept
    coding: http://snomed.info/id/12893009
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 12893009
      display:
        v: Biological
characteristic:
  definition: Reference
    l: mii-exa-mtb-study-cldn6-eligibility-criteria
    reference:
      v: Group/mii-exa-mtb-study-cldn6-eligibility-criteria

mii-exa-mtb-study-cldn6-comparison-group-1
type: Group
id:
  v: mii-exa-mtb-study-cldn6-comparison-group-1
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Group mii-exa-mtb-study-cldn6-comparison-group-1 type: Person actual: false Characteristics - Code Value[x] Exclude * Exposed to Biological: CLDN6 uRNA-LPX/CLDN6 modRNA-LPX false
type:
  v: person
actual:
  v: false
characteristic:
  code:
    text:
      v: Exposed to
  value: Reference
    l: mii-exa-mtb-study-cldn6-evidence-variable-1
    reference:
      v: EvidenceVariable/mii-exa-mtb-study-cldn6-evidence-variable-1
    display:
      v: Biological: CLDN6 uRNA-LPX/CLDN6 modRNA-LPX
  exclude:
    v: false

mii-exa-mtb-study-cldn6-evidence-variable-1
type: EvidenceVariable
id:
  v: mii-exa-mtb-study-cldn6-evidence-variable-1
text:
  status:
    v: generated
  div:
    v: Generated Narrative: EvidenceVariable mii-exa-mtb-study-cldn6-evidence-variable-1 status: Active UseContexts - Code Value[x] * SNOMED CT: 362956003 (Procedure/intervention (navigational concept)) Biological Characteristics - Definition[x] * Group: type = person; actual = false; quantity = 145
status:
  v: active
use context:
  code: http://snomed.info/id/362956003
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 362956003
    display:
      v: Procedure/intervention (navigational concept)
  value: CodeableConcept
    coding: http://snomed.info/id/12893009
      system:
        v: http://snomed.info/sct
        l: sct
      code:
        v: 12893009
      display:
        v: Biological
characteristic:
  definition: Reference
    l: mii-exa-mtb-study-cldn6-eligibility-criteria
    reference:
      v: Group/mii-exa-mtb-study-cldn6-eligibility-criteria

mii-exa-mtb-study-sponsor-biontech
type: Organization
id:
  v: mii-exa-mtb-study-sponsor-biontech
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Organization mii-exa-mtb-study-sponsor-biontech type: Clinical Research Sponsor name: BioNTech Cell & Gene Therapies GmbH
type:
  coding:
    system:
      v: http://terminology.hl7.org/CodeSystem/organization-type
      l: organization-type
    code:
      v: crs
    display:
      v: Clinical Research Sponsor
name:
  v: BioNTech Cell & Gene Therapies GmbH

mii-exa-mtb-study-investigator-biontech
type: PractitionerRole
id:
  v: mii-exa-mtb-study-investigator-biontech
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/modul-studie/StructureDefinition/mii-pr-studie-beteiligte-person
    l: mii-pr-studie-beteiligte-person
text:
  status:
    v: generated
  div:
    v: Generated Narrative: PractitionerRole mii-exa-mtb-study-investigator-biontech Profile: MII PR Studie Beteiligte Person code: Study coordinator
code:
  coding: http://snomed.info/id/768734005
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 768734005
    display:
      v: Study coordinator

mii-exa-mtb-study-cldn6-location-0
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-0
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-0 name: Peter MacCallum Cancer Centre address: Melbourne Victoria 3000 Australia Positions - Longitude Latitude * 144.96332 -37.814
name:
  v: Peter MacCallum Cancer Centre
address:
  city:
    v: Melbourne
  state:
    v: Victoria
  postal code:
    v: 3000
  country:
    v: Australia
position:
  longitude:
    v: 144.96332
  latitude:
    v: -37.814

mii-exa-mtb-study-cldn6-location-1
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-1
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-1 name: Charité - Universitätsmedizin Berlin - Campus Benjamin Franklin address: Berlin 12200 Germany Positions - Longitude Latitude * 13.41053 52.52437
name:
  v: Charité - Universitätsmedizin Berlin - Campus Benjamin Franklin
address:
  city:
    v: Berlin
  postal code:
    v: 12200
  country:
    v: Germany
position:
  longitude:
    v: 13.41053
  latitude:
    v: 52.52437

mii-exa-mtb-study-cldn6-location-2
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-2
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-2 name: Universitätsklinikum Erlangen - Hämatologie & Intrinsische Onkologie - Medizinische Klinik 5 address: Erlangen 91054 Germany Positions - Longitude Latitude * 11.00783 49.59099
name:
  v: Universitätsklinikum Erlangen - Hämatologie & Intrinsische Onkologie - Medizinische Klinik 5
address:
  city:
    v: Erlangen
  postal code:
    v: 91054
  country:
    v: Germany
position:
  longitude:
    v: 11.00783
  latitude:
    v: 49.59099

mii-exa-mtb-study-cldn6-location-3
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-3
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-3 name: Universitätsklinikum Hamburg Eppendorf - II Medizinische Klinik und Poliklinik address: Hamburg 20246 Germany Positions - Longitude Latitude * 10.01534 53.57532
name:
  v: Universitätsklinikum Hamburg Eppendorf - II Medizinische Klinik und Poliklinik
address:
  city:
    v: Hamburg
  postal code:
    v: 20246
  country:
    v: Germany
position:
  longitude:
    v: 10.01534
  latitude:
    v: 53.57532

mii-exa-mtb-study-cldn6-location-4
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-4
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-4 name: Medizinische Hochschule Hannover - Klinik für Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation address: Hannover 30625 Germany Positions - Longitude Latitude * 9.73322 52.37052
name:
  v: Medizinische Hochschule Hannover - Klinik für Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation
address:
  city:
    v: Hannover
  postal code:
    v: 30625
  country:
    v: Germany
position:
  longitude:
    v: 9.73322
  latitude:
    v: 52.37052

mii-exa-mtb-study-cldn6-location-5
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-5
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-5 name: Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg address: Heidelberg 69120 Germany Positions - Longitude Latitude * 8.69079 49.40768
name:
  v: Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg
address:
  city:
    v: Heidelberg
  postal code:
    v: 69120
  country:
    v: Germany
position:
  longitude:
    v: 8.69079
  latitude:
    v: 49.40768

mii-exa-mtb-study-cldn6-location-6
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-6
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-6 name: Universitätsklinikum Köln AÖR-Centrum für Integrierte Onkologie (CIO)-Studienzentrum der Klinik I für Innere Medizin (CTU Cologne) address: Köln 50937 Germany Positions - Longitude Latitude * 6.95 50.93333
name:
  v: Universitätsklinikum Köln AÖR-Centrum für Integrierte Onkologie (CIO)-Studienzentrum der Klinik I für Innere Medizin (CTU Cologne)
address:
  city:
    v: Köln
  postal code:
    v: 50937
  country:
    v: Germany
position:
  longitude:
    v: 6.95
  latitude:
    v: 50.93333

mii-exa-mtb-study-cldn6-location-7
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-7
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-7 name: Universitätsmedizin Mainz - III Medizinische Klinik und Poliklinik address: Mainz 55131 Germany Positions - Longitude Latitude * 8.2791 49.98419
name:
  v: Universitätsmedizin Mainz - III Medizinische Klinik und Poliklinik
address:
  city:
    v: Mainz
  postal code:
    v: 55131
  country:
    v: Germany
position:
  longitude:
    v: 8.2791
  latitude:
    v: 49.98419

mii-exa-mtb-study-cldn6-location-8
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-8
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-8 name: Universitätsklinikum Regensburg - Klinik und Poliklinik für Innere Medizin III address: Regensburg 93053 Germany Positions - Longitude Latitude * 12.10161 49.01513
name:
  v: Universitätsklinikum Regensburg - Klinik und Poliklinik für Innere Medizin III
address:
  city:
    v: Regensburg
  postal code:
    v: 93053
  country:
    v: Germany
position:
  longitude:
    v: 12.10161
  latitude:
    v: 49.01513

mii-exa-mtb-study-cldn6-location-9
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-9
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-9 name: He Nederlands Kanker Instituut (The Netherlands Cancer Institute) - Antoni van Leeuwenhoek Ziekenhuis (NKI-AVL) address: Amsterdam 1066 Netherlands Positions - Longitude Latitude * 4.88969 52.37403
name:
  v: He Nederlands Kanker Instituut (The Netherlands Cancer Institute) - Antoni van Leeuwenhoek Ziekenhuis (NKI-AVL)
address:
  city:
    v: Amsterdam
  postal code:
    v: 1066
  country:
    v: Netherlands
position:
  longitude:
    v: 4.88969
  latitude:
    v: 52.37403

mii-exa-mtb-study-cldn6-location-10
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-10
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-10 name: Erasmus MC - Universitair Medisch Centrum - Medical oncology address: Rotterdam 3015 Netherlands Positions - Longitude Latitude * 4.47917 51.9225
name:
  v: Erasmus MC - Universitair Medisch Centrum - Medical oncology
address:
  city:
    v: Rotterdam
  postal code:
    v: 3015
  country:
    v: Netherlands
position:
  longitude:
    v: 4.47917
  latitude:
    v: 51.9225

mii-exa-mtb-study-cldn6-location-11
type: Location
id:
  v: mii-exa-mtb-study-cldn6-location-11
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Location mii-exa-mtb-study-cldn6-location-11 name: Karolinska Comprehensive Cancer Center Cancerstudieenheten Huddinge Karolinska Universitetssjukhuset address: Stockholm 14186 Sweden Positions - Longitude Latitude * 18.0649 59.33258
name:
  v: Karolinska Comprehensive Cancer Center Cancerstudieenheten Huddinge Karolinska Universitetssjukhuset
address:
  city:
    v: Stockholm
  postal code:
    v: 14186
  country:
    v: Sweden
position:
  longitude:
    v: 18.0649
  latitude:
    v: 59.33258

mii-exa-mtb-study-tedova
type: ResearchStudy
id:
  v: mii-exa-mtb-study-tedova
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studie|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studie
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ResearchStudy mii-exa-mtb-study-tedova Profile: MII PR MTB Studieversion: null2026.0.0) identifier: MII_NS_MTB_NCT/04713514 status: Active
identifier:
  system:
    v: https://www.medizininformatik-initiative.de/fhir/modul-mtb/sid/nct
    l: nct
  value:
    v: 04713514
status:
  v: active

mii-exa-mtb-study-request-tedova
type: ServiceRequest
id:
  v: mii-exa-mtb-study-request-tedova
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studieneinschluss-anfrage|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studieneinschluss-anfrage
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: ServiceRequest mii-exa-mtb-study-request-tedova Profile: MII PR MTB Studieneinschluss Anfrageversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 2.2 status: Draft intent: Proposal category: Clinical trial (procedure) code: Referral to clinical trial (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 supportingInfo: ResearchStudy: identifier = https://www.medizininformatik-initiative.de/fhir/modul-mtb/sid/nct#MII_NS_MTB_NCT#04713514; status = active
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: Decimal
    v: 2.2
status:
  v: draft
intent:
  v: proposal
category:
  coding: http://snomed.info/id/110465008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 110465008
    display:
      v: Clinical trial (procedure)
code:
  coding: http://snomed.info/id/702475000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 702475000
    display:
      v: Referral to clinical trial (procedure)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
supporting info:
  l: mii-exa-mtb-study-tedova
  reference:
    v: ResearchStudy/mii-exa-mtb-study-tedova

mii-exa-mtb-study-ccne1
type: ResearchStudy
id:
  v: mii-exa-mtb-study-ccne1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studie|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studie
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ResearchStudy mii-exa-mtb-study-ccne1 Profile: MII PR MTB Studieversion: null2026.0.0) status: Active
status:
  v: active

mii-exa-mtb-study-request-ccne1
type: ServiceRequest
id:
  v: mii-exa-mtb-study-request-ccne1
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studieneinschluss-anfrage|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-studieneinschluss-anfrage
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: ServiceRequest mii-exa-mtb-study-request-ccne1 Profile: MII PR MTB Studieneinschluss Anfrageversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 2.3 status: Draft intent: Proposal category: Clinical trial (procedure) code: Referral to clinical trial (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 supportingInfo: ResearchStudy: status = active
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: Decimal
    v: 2.3
status:
  v: draft
intent:
  v: proposal
category:
  coding: http://snomed.info/id/110465008
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 110465008
    display:
      v: Clinical trial (procedure)
code:
  coding: http://snomed.info/id/702475000
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 702475000
    display:
      v: Referral to clinical trial (procedure)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
supporting info:
  l: mii-exa-mtb-study-ccne1
  reference:
    v: ResearchStudy/mii-exa-mtb-study-ccne1

mii-exa-mtb-medication-request-mirvetuximab
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-mirvetuximab
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-mirvetuximab Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 1 MII EX MTB Empfehlung Evidenzgraduierung: m1A MII EX MTB Empfehlung Publikation: http://doi.org/10.1200/JCO.2022.40.16_suppl.5512 MII EX MTB Empfehlung Publikation: http://www.ncbi.nlm.nih.gov/pubmed/38055253 status: Completed intent: Proposal medication: MIRVETUXIMAB SORAVTANSINE subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet basedOn: CarePlan: status = active; intent = plan; category = prätherapeutische Tumorkonferenz (Festlegung der Therapiestrategie); created = 2023-03-28
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: PositiveInt
    v: 1
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-evidenzgraduierung
    l: mii-ex-mtb-empfehlung-evidenzgraduierung
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-empfehlung-evidenzgrad
        l: mii-cs-mtb-empfehlung-evidenzgrad
      code:
        v: m1A
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://doi.org
      l: doi.org
    value:
      v: 10.1200/JCO.2022.40.16_suppl.5512
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://www.ncbi.nlm.nih.gov/pubmed
      l: pubmed
    value:
      v: 38055253
status:
  v: completed
intent:
  v: proposal
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: 98DE7VN88D
    display:
      v: MIRVETUXIMAB SORAVTANSINE
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX26
    display:
      v: Mirvetuximab soravtansin
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FX
    display:
      v: Andere monoklonale Antikörper und Antikörper-Wirkstoff-Konjugate
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2
based on:
  l: mii-exa-mtb-kim-musterperson-therapieplan
  reference:
    v: CarePlan/mii-exa-mtb-kim-musterperson-therapieplan

mii-exa-mtb-medication-request-trastuzumab-deruxtecan
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-trastuzumab-deruxtecan
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-trastuzumab-deruxtecan Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 3 MII EX MTB Empfehlung Evidenzgraduierung: m1B MII EX MTB Empfehlung Publikation: http://www.ncbi.nlm.nih.gov/pubmed/35665782 MII EX MTB Empfehlung Publikation: http://www.ncbi.nlm.nih.gov/pubmed/37870536 MII EX MTB Empfehlung Publikation: http://doi.org/10.1200/JCO.2023.41.17_suppl.LBA3000 status: Draft intent: Proposal medication: Trastuzumab deruxtecan subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: PositiveInt
    v: 3
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-evidenzgraduierung
    l: mii-ex-mtb-empfehlung-evidenzgraduierung
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-empfehlung-evidenzgrad
        l: mii-cs-mtb-empfehlung-evidenzgrad
      code:
        v: m1B
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://www.ncbi.nlm.nih.gov/pubmed
      l: pubmed
    value:
      v: 35665782
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://www.ncbi.nlm.nih.gov/pubmed
      l: pubmed
    value:
      v: 37870536
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://doi.org
      l: doi.org
    value:
      v: 10.1200/JCO.2023.41.17_suppl.LBA3000
status:
  v: draft
intent:
  v: proposal
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01FD04
    display:
      v: Trastuzumab deruxtecan
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2

mii-exa-mtb-medication-request-adavosertib
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-adavosertib
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-adavosertib Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) status: Draft intent: Option medication: ADAVOSERTIB subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet
status:
  v: draft
intent:
  v: option
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: K2T6HJX3I3
    display:
      v: ADAVOSERTIB
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2

mii-exa-mtb-medication-request-carboplatin
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-carboplatin
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-carboplatin Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) status: Draft intent: Option medication: Carboplatin subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet
status:
  v: draft
intent:
  v: option
medication: CodeableConcept
  coding:
    system:
      v: http://fhir.de/CodeSystem/bfarm/atc
      l: atc
    version:
      v: 2025
    code:
      v: L01XA02
    display:
      v: Carboplatin
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2

mii-exa-mtb-request-group-adavosertib-carboplatin
type: RequestGroup
id:
  v: mii-exa-mtb-request-group-adavosertib-carboplatin
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung-kombination|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung-kombination
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: RequestGroup mii-exa-mtb-request-group-adavosertib-carboplatin Profile: MII PR MTB Therapieempfehlung Kombinationstherapieversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 4 MII EX MTB Empfehlung Evidenzgraduierung: m1B MII EX MTB Empfehlung Publikation: http://www.ncbi.nlm.nih.gov/pubmed/37236033 status: Draft intent: Proposal code: Chemotherapie + zielgerichtete Substanzen subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 Actions - Resource * MedicationRequest: status = draft; intent = option; medication[x] = Carboplatin; authoredOn = 2023-03-28
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: PositiveInt
    v: 4
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-evidenzgraduierung
    l: mii-ex-mtb-empfehlung-evidenzgraduierung
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-empfehlung-evidenzgrad
        l: mii-cs-mtb-empfehlung-evidenzgrad
      code:
        v: m1B
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://www.ncbi.nlm.nih.gov/pubmed
      l: pubmed
    value:
      v: 37236033
status:
  v: draft
intent:
  v: proposal
code:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-typ
      l: mii-cs-onko-therapie-typ
    code:
      v: CZ
    display:
      v: Chemotherapie + zielgerichtete Substanzen
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
action:
  resource:
    l: mii-exa-mtb-medication-request-carboplatin
    reference:
      v: MedicationRequest/mii-exa-mtb-medication-request-carboplatin

mii-exa-mtb-medication-request-lunresertib
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-lunresertib
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-lunresertib Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) status: Draft intent: Option medication: LUNRESERTIB subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet
status:
  v: draft
intent:
  v: option
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: N95U3A7N57
    display:
      v: LUNRESERTIB
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2

mii-exa-mtb-medication-request-camonsertib
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-camonsertib
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: generated
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-camonsertib Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) status: Draft intent: Option medication: CAMONSERTIB subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet
status:
  v: draft
intent:
  v: option
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: S1Z7Y5G56T
    display:
      v: CAMONSERTIB
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2

mii-exa-mtb-request-group-lunresertib-camonsertib
type: RequestGroup
id:
  v: mii-exa-mtb-request-group-lunresertib-camonsertib
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung-kombination|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung-kombination
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: RequestGroup mii-exa-mtb-request-group-lunresertib-camonsertib Profile: MII PR MTB Therapieempfehlung Kombinationstherapieversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 5 MII EX MTB Empfehlung Evidenzgraduierung: m1B MII EX MTB Empfehlung Publikation: http://doi.org/10.1158/1535-7163.TARG-23-PR008 status: Draft intent: Proposal code: zielgerichtete Substanzen subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 Actions - Resource * MedicationRequest: status = draft; intent = option; medication[x] = CAMONSERTIB; authoredOn = 2023-03-28
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: PositiveInt
    v: 5
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-evidenzgraduierung
    l: mii-ex-mtb-empfehlung-evidenzgraduierung
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-empfehlung-evidenzgrad
        l: mii-cs-mtb-empfehlung-evidenzgrad
      code:
        v: m1B
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://doi.org
      l: doi.org
    value:
      v: 10.1158/1535-7163.TARG-23-PR008
status:
  v: draft
intent:
  v: proposal
code:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapie-typ
      l: mii-cs-onko-therapie-typ
    code:
      v: ZS
    display:
      v: zielgerichtete Substanzen
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
action:
  resource:
    l: mii-exa-mtb-medication-request-camonsertib
    reference:
      v: MedicationRequest/mii-exa-mtb-medication-request-camonsertib

mii-exa-mtb-medication-request-cobimetinib
type: MedicationRequest
id:
  v: mii-exa-mtb-medication-request-cobimetinib
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieempfehlung
text:
  status:
    v: extensions
  div:
    v: Generated Narrative: MedicationRequest mii-exa-mtb-medication-request-cobimetinib Profile: MII PR MTB Therapieempfehlung Systemische Therapieversion: null2026.0.0) MII EX MTB Empfehlung Priorität: 6 MII EX MTB Empfehlung Evidenzgraduierung: m3 MII EX MTB Empfehlung Publikation: http://www.ncbi.nlm.nih.gov/pubmed/31209687 status: Draft intent: Option medication: COBIMETINIB subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 authoredOn: 2023-03-28 reasonReference: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-prioritaet
    l: mii-ex-mtb-empfehlung-prioritaet
  value: PositiveInt
    v: 6
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-evidenzgraduierung
    l: mii-ex-mtb-empfehlung-evidenzgraduierung
  value: CodeableConcept
    coding:
      system:
        v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-empfehlung-evidenzgrad
        l: mii-cs-mtb-empfehlung-evidenzgrad
      code:
        v: m3
extension:
  url:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-ex-mtb-empfehlung-publikation
    l: mii-ex-mtb-empfehlung-publikation
  value: Identifier
    system:
      v: http://www.ncbi.nlm.nih.gov/pubmed
      l: pubmed
    value:
      v: 31209687
status:
  v: draft
intent:
  v: option
medication: CodeableConcept
  coding:
    system:
      v: http://fdasis.nlm.nih.gov
      l: fdasis.nlm.nih.gov
    code:
      v: ER29L26N1X
    display:
      v: COBIMETINIB
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
authored on:
  v: 2023-03-28
reason reference:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2

mii-exa-mtb-kim-musterperson-therapieplan
type: CarePlan
id:
  v: mii-exa-mtb-kim-musterperson-therapieplan
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieplan|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-therapieplan
text:
  status:
    v: generated
  div:
    v: Generated Narrative: CarePlan mii-exa-mtb-kim-musterperson-therapieplan Profile: MII PR MTB Therapieplanversion: null2026.0.0) status: Active intent: Plan category: prätherapeutische Tumorkonferenz (Festlegung der Therapiestrategie) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 created: 2023-03-28 addresses: Condition Bösartige Neubildung: Peritoneum, nicht näher bezeichnet supportingInfo: ClinicalImpression: status = completed; effective[x] = 2023-01-20 --> 2023-03-28 activity outcomeReference: Procedure 367336001 reference: MedicationRequest: extension = 1,m1A,http://doi.org#10.1200/JCO.2022.40.16_suppl.5512,http://www.ncbi.nlm.nih.gov/pubmed#38055253; status = completed; intent = proposal; medication[x] = MIRVETUXIMAB SORAVTANSINE; authoredOn = 2023-03-28 activity reference: ServiceRequest Referral to clinical trial (procedure) activity reference: ServiceRequest Referral to clinical trial (procedure) activity reference: ServiceRequest Referral to clinical trial (procedure) activity reference: MedicationRequest: extension = 3,m1B,http://www.ncbi.nlm.nih.gov/pubmed#35665782,http://www.ncbi.nlm.nih.gov/pubmed#37870536,http://doi.org#10.1200/JCO.2023.41.17_suppl.LBA3000; status = draft; intent = proposal; medication[x] = Trastuzumab deruxtecan; authoredOn = 2023-03-28 activity reference: RequestGroup Chemotherapie + zielgerichtete Substanzen activity reference: RequestGroup zielgerichtete Substanzen activity reference: MedicationRequest: extension = 6,m3,http://www.ncbi.nlm.nih.gov/pubmed#31209687; status = draft; intent = option; medication[x] = COBIMETINIB; authoredOn = 2023-03-28 activity reference: ServiceRequest Genetic consultation (procedure) activity reference: ServiceRequest Refer for histology (procedure) activity reference: ServiceRequest Biopsy (procedure)
status:
  v: active
intent:
  v: plan
category:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-therapieplanung-typ
      l: mii-cs-onko-therapieplanung-typ
    code:
      v: praeth
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
created:
  v: 2023-03-28
addresses:
  l: PatientKimMusterperson-PrimaryDiagnosis-2
  reference:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2
supporting info:
  l: mii-exa-mtb-kim-musterperson-behandlungsepisode
  reference:
    v: ClinicalImpression/mii-exa-mtb-kim-musterperson-behandlungsepisode
activity:
  outcome reference:
    l: MTBChemo2Procedure
    reference:
      v: Procedure/MTBChemo2Procedure
  reference:
    l: mii-exa-mtb-medication-request-mirvetuximab
    reference:
      v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
activity:
  reference:
    l: mii-exa-mtb-study-request-cldn6
    reference:
      v: ServiceRequest/mii-exa-mtb-study-request-cldn6
activity:
  reference:
    l: mii-exa-mtb-study-request-tedova
    reference:
      v: ServiceRequest/mii-exa-mtb-study-request-tedova
activity:
  reference:
    l: mii-exa-mtb-study-request-ccne1
    reference:
      v: ServiceRequest/mii-exa-mtb-study-request-ccne1
activity:
  reference:
    l: mii-exa-mtb-medication-request-trastuzumab-deruxtecan
    reference:
      v: MedicationRequest/mii-exa-mtb-medication-request-trastuzumab-deruxtecan
activity:
  reference:
    l: mii-exa-mtb-request-group-adavosertib-carboplatin
    reference:
      v: RequestGroup/mii-exa-mtb-request-group-adavosertib-carboplatin
activity:
  reference:
    l: mii-exa-mtb-request-group-lunresertib-camonsertib
    reference:
      v: RequestGroup/mii-exa-mtb-request-group-lunresertib-camonsertib
activity:
  reference:
    l: mii-exa-mtb-medication-request-cobimetinib
    reference:
      v: MedicationRequest/mii-exa-mtb-medication-request-cobimetinib
activity:
  reference:
    l: mii-exa-mtb-kim-humangenetische-beratung-aszites
    reference:
      v: ServiceRequest/mii-exa-mtb-kim-humangenetische-beratung-aszites
activity:
  reference:
    l: mii-exa-mtb-kim-histologie-evaluation-aszites
    reference:
      v: ServiceRequest/mii-exa-mtb-kim-histologie-evaluation-aszites
activity:
  reference:
    l: mii-exa-mtb-kim-rebiopsie-aszites
    reference:
      v: ServiceRequest/mii-exa-mtb-kim-rebiopsie-aszites

mii-exa-mtb-kim-tumorzellgehalt-aszites
type: Observation
id:
  v: mii-exa-mtb-kim-tumorzellgehalt-aszites
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-tumorzellgehalt|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-tumorzellgehalt
text:
  status:
    v: generated
  div:
    v: Generated Narrative: Observation mii-exa-mtb-kim-tumorzellgehalt-aszites Profile: MII PR MTB Tumorzellgehaltversion: null2026.0.0) status: Final code: Cells with cytogenetic abnormality [#] in Blood or Tissue by Molecular genetics method value: 0.028 % (Details: UCUM code% = '%') method: Histologisch
status:
  v: final
code:
  coding: https://loinc.org/rdf/93356-4
    system:
      v: http://loinc.org
      l: loinc.org
    code:
      v: 93356-4
    display:
      v: Cells with cytogenetic abnormality [#] in Blood or Tissue by Molecular genetics method
value: Quantity
  value:
    v: 0.028
  system:
    v: http://unitsofmeasure.org
    l: unitsofmeasure.org
  code:
    v: %
method:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-bestimmungsmethode-tumorzellgehalt
      l: mii-cs-mtb-bestimmungsmethode-tumorzellgehalt
    code:
      v: histologic

mii-exa-mtb-kim-humangenetische-beratung-aszites
type: ServiceRequest
id:
  v: mii-exa-mtb-kim-humangenetische-beratung-aszites
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-humangenetische-beratung-auftrag|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-humangenetische-beratung-auftrag
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ServiceRequest mii-exa-mtb-kim-humangenetische-beratung-aszites Profile: MII PR MTB Human-genetische Beratung Auftragversion: null2026.0.0) status: Completed intent: Proposal code: Genetic consultation (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 reasonCode: Zweittumor specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: completed
intent:
  v: proposal
code:
  coding: http://snomed.info/id/788339009
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 788339009
    display:
      v: Genetic consultation (procedure)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
reason code:
  coding:
    system:
      v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-auftrag-begruendung
      l: mii-cs-mtb-auftrag-begruendung
    code:
      v: secondary-tumor
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

mii-exa-mtb-kim-histologie-evaluation-aszites
type: ServiceRequest
id:
  v: mii-exa-mtb-kim-histologie-evaluation-aszites
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-histologie-evaluation-auftrag|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-histologie-evaluation-auftrag
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ServiceRequest mii-exa-mtb-kim-histologie-evaluation-aszites Profile: MII PR MTB Histologie-Evaluation Auftragversion: null2026.0.0) status: Draft intent: Proposal code: Refer for histology (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 reasonReference: Observation Cells with cytogenetic abnormality [#] in Blood or Tissue by Molecular genetics method specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: draft
intent:
  v: proposal
code:
  coding: http://snomed.info/id/183825009
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 183825009
    display:
      v: Refer for histology (procedure)
subject:
  l: PatientKimMusterperson
  reference:
    v: Patient/PatientKimMusterperson
reason reference:
  l: mii-exa-mtb-kim-tumorzellgehalt-aszites
  reference:
    v: Observation/mii-exa-mtb-kim-tumorzellgehalt-aszites
specimen:
  l: PatientKimMusterperson-AscitesSpecimen-2
  reference:
    v: Specimen/PatientKimMusterperson-AscitesSpecimen-2

mii-exa-mtb-kim-rebiopsie-aszites
type: ServiceRequest
id:
  v: mii-exa-mtb-kim-rebiopsie-aszites
meta:
  profile:
    v: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-biopsie-auftrag|2026.0.0
    l: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-biopsie-auftrag
text:
  status:
    v: generated
  div:
    v: Generated Narrative: ServiceRequest mii-exa-mtb-kim-rebiopsie-aszites Profile: MII PR MTB Biopsie Auftragversion: null2026.0.0) status: Completed intent: Proposal code: Biopsy (procedure) subject: Kim Musterperson (no stated gender), DoB: 1956-03-14 reasonReference: Observation Cells with cytogenetic abnormality [#] in Blood or Tissue by Molecular genetics method specimen: Specimen: accessionIdentifier = Z230201/23; type = Ascitic fluid specimen (specimen)
status:
  v: completed
intent:
  v: proposal
code:
  coding: http://snomed.info/id/86273004
    system:
      v: http://snomed.info/sct
      l: sct
    code:
      v: 86273004

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-4-ER
  l: PatientKimMusterperson-MolecularPathologyObservation-4-ER
resource: PatientKimMusterperson-MolecularPathologyObservation-4-ER
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-MolecularPathologyObservation-4-ER
    l: PatientKimMusterperson-MolecularPathologyObservation-4-ER

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-5-PR
  l: PatientKimMusterperson-MolecularPathologyObservation-5-PR
resource: PatientKimMusterperson-MolecularPathologyObservation-5-PR
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-MolecularPathologyObservation-5-PR
    l: PatientKimMusterperson-MolecularPathologyObservation-5-PR

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-6-p53
  l: PatientKimMusterperson-MolecularPathologyObservation-6-p53
resource: PatientKimMusterperson-MolecularPathologyObservation-6-p53
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-MolecularPathologyObservation-6-p53
    l: PatientKimMusterperson-MolecularPathologyObservation-6-p53

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-MolecularPathologyObservation-7-p53
  l: PatientKimMusterperson-MolecularPathologyObservation-7-p53
resource: PatientKimMusterperson-MolecularPathologyObservation-7-p53
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-MolecularPathologyObservation-7-p53
    l: PatientKimMusterperson-MolecularPathologyObservation-7-p53

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-1
  l: PatientKimMusterperson-Procedure-1
resource: PatientKimMusterperson-Procedure-1
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-1
    l: PatientKimMusterperson-Procedure-1

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-2
  l: PatientKimMusterperson-Procedure-2
resource: PatientKimMusterperson-Procedure-2
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-2
    l: PatientKimMusterperson-Procedure-2

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-3
  l: PatientKimMusterperson-Procedure-3
resource: PatientKimMusterperson-Procedure-3
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-3
    l: PatientKimMusterperson-Procedure-3

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-4
  l: PatientKimMusterperson-Procedure-4
resource: PatientKimMusterperson-Procedure-4
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-4
    l: PatientKimMusterperson-Procedure-4

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-5
  l: PatientKimMusterperson-Procedure-5
resource: PatientKimMusterperson-Procedure-5
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-5
    l: PatientKimMusterperson-Procedure-5

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-6
  l: PatientKimMusterperson-Procedure-6
resource: PatientKimMusterperson-Procedure-6
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-6
    l: PatientKimMusterperson-Procedure-6

full url:
  v: http://example.org/fhir/Procedure/PatientKimMusterperson-Procedure-7
  l: PatientKimMusterperson-Procedure-7
resource: PatientKimMusterperson-Procedure-7
request:
  method:
    v: PUT
  url:
    v: Procedure/PatientKimMusterperson-Procedure-7
    l: PatientKimMusterperson-Procedure-7

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-1
  l: PatientKimMusterperson-Observation-1
resource: PatientKimMusterperson-Observation-1
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-1
    l: PatientKimMusterperson-Observation-1

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-2
  l: PatientKimMusterperson-Observation-2
resource: PatientKimMusterperson-Observation-2
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-2
    l: PatientKimMusterperson-Observation-2

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-3
  l: PatientKimMusterperson-Observation-3
resource: PatientKimMusterperson-Observation-3
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-3
    l: PatientKimMusterperson-Observation-3

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-4
  l: PatientKimMusterperson-Observation-4
resource: PatientKimMusterperson-Observation-4
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-4
    l: PatientKimMusterperson-Observation-4

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-5
  l: PatientKimMusterperson-Observation-5
resource: PatientKimMusterperson-Observation-5
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-5
    l: PatientKimMusterperson-Observation-5

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-6
  l: PatientKimMusterperson-Observation-6
resource: PatientKimMusterperson-Observation-6
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-6
    l: PatientKimMusterperson-Observation-6

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-7
  l: PatientKimMusterperson-Observation-7
resource: PatientKimMusterperson-Observation-7
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-7
    l: PatientKimMusterperson-Observation-7

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-8
  l: PatientKimMusterperson-Observation-8
resource: PatientKimMusterperson-Observation-8
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-8
    l: PatientKimMusterperson-Observation-8

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-9
  l: PatientKimMusterperson-Observation-9
resource: PatientKimMusterperson-Observation-9
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-9
    l: PatientKimMusterperson-Observation-9

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-10
  l: PatientKimMusterperson-Observation-10
resource: PatientKimMusterperson-Observation-10
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-10
    l: PatientKimMusterperson-Observation-10

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-11
  l: PatientKimMusterperson-Observation-11
resource: PatientKimMusterperson-Observation-11
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-11
    l: PatientKimMusterperson-Observation-11

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-12
  l: PatientKimMusterperson-Observation-12
resource: PatientKimMusterperson-Observation-12
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-12
    l: PatientKimMusterperson-Observation-12

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-13
  l: PatientKimMusterperson-Observation-13
resource: PatientKimMusterperson-Observation-13
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-13
    l: PatientKimMusterperson-Observation-13

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-14
  l: PatientKimMusterperson-Observation-14
resource: PatientKimMusterperson-Observation-14
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-14
    l: PatientKimMusterperson-Observation-14

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-15
  l: PatientKimMusterperson-Observation-15
resource: PatientKimMusterperson-Observation-15
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-15
    l: PatientKimMusterperson-Observation-15

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-16
  l: PatientKimMusterperson-Observation-16
resource: PatientKimMusterperson-Observation-16
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-16
    l: PatientKimMusterperson-Observation-16

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-17
  l: PatientKimMusterperson-Observation-17
resource: PatientKimMusterperson-Observation-17
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-17
    l: PatientKimMusterperson-Observation-17

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-18
  l: PatientKimMusterperson-Observation-18
resource: PatientKimMusterperson-Observation-18
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-18
    l: PatientKimMusterperson-Observation-18

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-19
  l: PatientKimMusterperson-Observation-19
resource: PatientKimMusterperson-Observation-19
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-19
    l: PatientKimMusterperson-Observation-19

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-20
  l: PatientKimMusterperson-Observation-20
resource: PatientKimMusterperson-Observation-20
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-20
    l: PatientKimMusterperson-Observation-20

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-21
  l: PatientKimMusterperson-Observation-21
resource: PatientKimMusterperson-Observation-21
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-21
    l: PatientKimMusterperson-Observation-21

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-22
  l: PatientKimMusterperson-Observation-22
resource: PatientKimMusterperson-Observation-22
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-22
    l: PatientKimMusterperson-Observation-22

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-23
  l: PatientKimMusterperson-Observation-23
resource: PatientKimMusterperson-Observation-23
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-23
    l: PatientKimMusterperson-Observation-23

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-24
  l: PatientKimMusterperson-Observation-24
resource: PatientKimMusterperson-Observation-24
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-24
    l: PatientKimMusterperson-Observation-24

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-25
  l: PatientKimMusterperson-Observation-25
resource: PatientKimMusterperson-Observation-25
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-25
    l: PatientKimMusterperson-Observation-25

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-26
  l: PatientKimMusterperson-Observation-26
resource: PatientKimMusterperson-Observation-26
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-26
    l: PatientKimMusterperson-Observation-26

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-27
  l: PatientKimMusterperson-Observation-27
resource: PatientKimMusterperson-Observation-27
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-27
    l: PatientKimMusterperson-Observation-27

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-29
  l: PatientKimMusterperson-Observation-29
resource: PatientKimMusterperson-Observation-29
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-29
    l: PatientKimMusterperson-Observation-29

full url:
  v: http://example.org/fhir/Observation/PatientKimMusterperson-Observation-30
  l: PatientKimMusterperson-Observation-30
resource: PatientKimMusterperson-Observation-30
request:
  method:
    v: PUT
  url:
    v: Observation/PatientKimMusterperson-Observation-30
    l: PatientKimMusterperson-Observation-30

full url:
  v: http://example.org/fhir/ClinicalImpression/MII-EXA-MTB-Follow-Up-ClinicalImpression-1
  l: MII-EXA-MTB-Follow-Up-ClinicalImpression-1
resource: MII-EXA-MTB-Follow-Up-ClinicalImpression-1
request:
  method:
    v: PUT
  url:
    v: ClinicalImpression/MII-EXA-MTB-Follow-Up-ClinicalImpression-1
    l: MII-EXA-MTB-Follow-Up-ClinicalImpression-1

full url:
  v: http://example.org/fhir/Procedure/MII-EXA-MTB-Systemische-Therapie-1
  l: MII-EXA-MTB-Systemische-Therapie-1
resource: MII-EXA-MTB-Systemische-Therapie-1
request:
  method:
    v: PUT
  url:
    v: Procedure/MII-EXA-MTB-Systemische-Therapie-1
    l: MII-EXA-MTB-Systemische-Therapie-1

full url:
  v: http://example.org/fhir/MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-1
  l: MII-EXA-MTB-Systemische-Therapie-Medication-1
resource: MII-EXA-MTB-Systemische-Therapie-Medication-1
request:
  method:
    v: PUT
  url:
    v: MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-1
    l: MII-EXA-MTB-Systemische-Therapie-Medication-1

full url:
  v: http://example.org/fhir/MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-2
  l: MII-EXA-MTB-Systemische-Therapie-Medication-2
resource: MII-EXA-MTB-Systemische-Therapie-Medication-2
request:
  method:
    v: PUT
  url:
    v: MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-2
    l: MII-EXA-MTB-Systemische-Therapie-Medication-2

full url:
  v: http://example.org/fhir/MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-3
  l: MII-EXA-MTB-Systemische-Therapie-Medication-3
resource: MII-EXA-MTB-Systemische-Therapie-Medication-3
request:
  method:
    v: PUT
  url:
    v: MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-3
    l: MII-EXA-MTB-Systemische-Therapie-Medication-3

full url:
  v: http://example.org/fhir/MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-4
  l: MII-EXA-MTB-Systemische-Therapie-Medication-4
resource: MII-EXA-MTB-Systemische-Therapie-Medication-4
request:
  method:
    v: PUT
  url:
    v: MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-4
    l: MII-EXA-MTB-Systemische-Therapie-Medication-4

full url:
  v: http://example.org/fhir/MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-5
  l: MII-EXA-MTB-Systemische-Therapie-Medication-5
resource: MII-EXA-MTB-Systemische-Therapie-Medication-5
request:
  method:
    v: PUT
  url:
    v: MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-5
    l: MII-EXA-MTB-Systemische-Therapie-Medication-5

full url:
  v: http://example.org/fhir/MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-6
  l: MII-EXA-MTB-Systemische-Therapie-Medication-6
resource: MII-EXA-MTB-Systemische-Therapie-Medication-6
request:
  method:
    v: PUT
  url:
    v: MedicationStatement/MII-EXA-MTB-Systemische-Therapie-Medication-6
    l: MII-EXA-MTB-Systemische-Therapie-Medication-6

full url:
  v: http://example.org/fhir/Observation/MII-EXA-MTB-Response-Befund-1
  l: MII-EXA-MTB-Response-Befund-1
resource: MII-EXA-MTB-Response-Befund-1
request:
  method:
    v: PUT
  url:
    v: Observation/MII-EXA-MTB-Response-Befund-1
    l: MII-EXA-MTB-Response-Befund-1

full url:
  v: http://example.org/fhir/Observation/MII-EXA-MTB-Response-Befund-2
  l: MII-EXA-MTB-Response-Befund-2
resource: MII-EXA-MTB-Response-Befund-2
request:
  method:
    v: PUT
  url:
    v: Observation/MII-EXA-MTB-Response-Befund-2
    l: MII-EXA-MTB-Response-Befund-2

full url:
  v: http://example.org/fhir/Claim/MII-EXA-MTB-Antrag-Kostenuebernahme-1
  l: MII-EXA-MTB-Antrag-Kostenuebernahme-1
resource: MII-EXA-MTB-Antrag-Kostenuebernahme-1
request:
  method:
    v: PUT
  url:
    v: Claim/MII-EXA-MTB-Antrag-Kostenuebernahme-1
    l: MII-EXA-MTB-Antrag-Kostenuebernahme-1

full url:
  v: http://example.org/fhir/ClaimResponse/MII-EXA-MTB-Antwort-Kostenuebernahme-1
  l: MII-EXA-MTB-Antwort-Kostenuebernahme-1
resource: MII-EXA-MTB-Antwort-Kostenuebernahme-1
request:
  method:
    v: PUT
  url:
    v: ClaimResponse/MII-EXA-MTB-Antwort-Kostenuebernahme-1
    l: MII-EXA-MTB-Antwort-Kostenuebernahme-1

full url:
  v: http://example.org/fhir/Specimen/PatientKimMusterperson-Specimen-1
  l: PatientKimMusterperson-Specimen-1
resource: PatientKimMusterperson-Specimen-1
request:
  method:
    v: PUT
  url:
    v: Specimen/PatientKimMusterperson-Specimen-1
    l: PatientKimMusterperson-Specimen-1

full url:
  v: http://example.org/fhir/Procedure/MTBChemo1Procedure
  l: MTBChemo1Procedure
resource: MTBChemo1Procedure
request:
  method:
    v: PUT
  url:
    v: Procedure/MTBChemo1Procedure
    l: MTBChemo1Procedure

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement1
  l: MTBChemo1MedicationStatement1
resource: MTBChemo1MedicationStatement1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement1-1
  l: MTBChemo1MedicationStatement1-1
resource: MTBChemo1MedicationStatement1-1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement1-1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement1-2
  l: MTBChemo1MedicationStatement1-2
resource: MTBChemo1MedicationStatement1-2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement1-2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement2
  l: MTBChemo1MedicationStatement2
resource: MTBChemo1MedicationStatement2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement2-1
  l: MTBChemo1MedicationStatement2-1
resource: MTBChemo1MedicationStatement2-1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement2-1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement2-2
  l: MTBChemo1MedicationStatement2-2
resource: MTBChemo1MedicationStatement2-2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement2-2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement3
  l: MTBChemo1MedicationStatement3
resource: MTBChemo1MedicationStatement3
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement3

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement3-1
  l: MTBChemo1MedicationStatement3-1
resource: MTBChemo1MedicationStatement3-1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement3-1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement3-2
  l: MTBChemo1MedicationStatement3-2
resource: MTBChemo1MedicationStatement3-2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement3-2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement4
  l: MTBChemo1MedicationStatement4
resource: MTBChemo1MedicationStatement4
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement4

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement4-1
  l: MTBChemo1MedicationStatement4-1
resource: MTBChemo1MedicationStatement4-1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement4-1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement4-2
  l: MTBChemo1MedicationStatement4-2
resource: MTBChemo1MedicationStatement4-2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement4-2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement5
  l: MTBChemo1MedicationStatement5
resource: MTBChemo1MedicationStatement5
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement5

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement5-1
  l: MTBChemo1MedicationStatement5-1
resource: MTBChemo1MedicationStatement5-1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement5-1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement5-2
  l: MTBChemo1MedicationStatement5-2
resource: MTBChemo1MedicationStatement5-2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement5-2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement6
  l: MTBChemo1MedicationStatement6
resource: MTBChemo1MedicationStatement6
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement6

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement6-1
  l: MTBChemo1MedicationStatement6-1
resource: MTBChemo1MedicationStatement6-1
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement6-1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo1MedicationStatement6-2
  l: MTBChemo1MedicationStatement6-2
resource: MTBChemo1MedicationStatement6-2
request:
  method:
    v: PUT
  url:
    l: MTBChemo1MedicationStatement6-2

full url:
  v: http://example.org/fhir/Procedure/MTBChemo2Procedure
  l: MTBChemo2Procedure
resource: MTBChemo2Procedure
request:
  method:
    v: PUT
  url:
    v: Procedure/MTBChemo2Procedure
    l: MTBChemo2Procedure

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo2MedicationStatement1
  l: MTBChemo2MedicationStatement1
resource: MTBChemo2MedicationStatement1
request:
  method:
    v: PUT
  url:
    l: MTBChemo2MedicationStatement1

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo2MedicationStatement2
  l: MTBChemo2MedicationStatement2
resource: MTBChemo2MedicationStatement2
request:
  method:
    v: PUT
  url:
    l: MTBChemo2MedicationStatement2

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo2MedicationStatement3
  l: MTBChemo2MedicationStatement3
resource: MTBChemo2MedicationStatement3
request:
  method:
    v: PUT
  url:
    l: MTBChemo2MedicationStatement3

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo2MedicationStatement4
  l: MTBChemo2MedicationStatement4
resource: MTBChemo2MedicationStatement4
request:
  method:
    v: PUT
  url:
    l: MTBChemo2MedicationStatement4

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo2MedicationStatement5
  l: MTBChemo2MedicationStatement5
resource: MTBChemo2MedicationStatement5
request:
  method:
    v: PUT
  url:
    l: MTBChemo2MedicationStatement5

full url:
  v: http://example.org/fhir/MedicationStatement/MTBChemo2MedicationStatement6
  l: MTBChemo2MedicationStatement6
resource: MTBChemo2MedicationStatement6
request:
  method:
    v: PUT
  url:
    l: MTBChemo2MedicationStatement6

full url:
  v: http://example.org/fhir/DiagnosticReport/mii-exa-mtb-kim-musterperson-ngs-bericht
  l: mii-exa-mtb-kim-musterperson-ngs-bericht
resource: mii-exa-mtb-kim-musterperson-ngs-bericht
request:
  method:
    v: PUT
  url:
    v: DiagnosticReport/mii-exa-mtb-kim-musterperson-ngs-bericht
    l: mii-exa-mtb-kim-musterperson-ngs-bericht

full url:
  v: http://example.org/fhir/Procedure/mii-exa-mtb-kim-musterperson-genomic-study
  l: mii-exa-mtb-kim-musterperson-genomic-study
resource: mii-exa-mtb-kim-musterperson-genomic-study
request:
  method:
    v: PUT
  url:
    v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study
    l: mii-exa-mtb-kim-musterperson-genomic-study

full url:
  v: http://example.org/fhir/Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
  l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
resource: mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
request:
  method:
    v: PUT
  url:
    v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-1
    l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-1

full url:
  v: http://example.org/fhir/Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
  l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
resource: mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
request:
  method:
    v: PUT
  url:
    v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-2
    l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-2

full url:
  v: http://example.org/fhir/Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
  l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
resource: mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
request:
  method:
    v: PUT
  url:
    v: Procedure/mii-exa-mtb-kim-musterperson-genomic-study-analysis-3
    l: mii-exa-mtb-kim-musterperson-genomic-study-analysis-3

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
  l: mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
resource: mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53
    l: mii-exa-mtb-kim-musterperson-EinfacheVariante-TP53

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53
  l: mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53
resource: mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53
    l: mii-exa-mtb-kim-musterperson-DiagnostischeImplikation-TP53

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
  l: mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
resource: mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1
    l: mii-exa-mtb-kim-musterperson-EinfacheVariante-PIK3R1

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1
  l: mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1
resource: mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1
    l: mii-exa-mtb-kim-musterperson-TherapeutischeImplikation-PIK3R1

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
  l: mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
resource: mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-musterperson-CNVariante-CCNE1
    l: mii-exa-mtb-kim-musterperson-CNVariante-CCNE1

full url:
  v: http://example.org/fhir/ServiceRequest/mii-exa-mtb-study-request-cldn6
  l: mii-exa-mtb-study-request-cldn6
resource: mii-exa-mtb-study-request-cldn6
request:
  method:
    v: PUT
  url:
    v: ServiceRequest/mii-exa-mtb-study-request-cldn6
    l: mii-exa-mtb-study-request-cldn6

full url:
  v: http://example.org/fhir/ResearchStudy/mii-exa-mtb-study-cldn6
  l: mii-exa-mtb-study-cldn6
resource: mii-exa-mtb-study-cldn6
request:
  method:
    v: PUT
  url:
    v: ResearchStudy/mii-exa-mtb-study-cldn6
    l: mii-exa-mtb-study-cldn6

full url:
  v: http://example.org/fhir/Group/mii-exa-mtb-study-cldn6-eligibility-criteria
  l: mii-exa-mtb-study-cldn6-eligibility-criteria
resource: mii-exa-mtb-study-cldn6-eligibility-criteria
request:
  method:
    v: PUT
  url:
    v: Group/mii-exa-mtb-study-cldn6-eligibility-criteria
    l: mii-exa-mtb-study-cldn6-eligibility-criteria

full url:
  v: http://example.org/fhir/Group/mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
  l: mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
resource: mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
request:
  method:
    v: PUT
  url:
    v: Group/mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups
    l: mii-exa-mtb-study-cldn6-eligibility-criteria-age-groups

full url:
  v: http://example.org/fhir/Group/mii-exa-mtb-study-cldn6-comparison-group-0
  l: mii-exa-mtb-study-cldn6-comparison-group-0
resource: mii-exa-mtb-study-cldn6-comparison-group-0
request:
  method:
    v: PUT
  url:
    v: Group/mii-exa-mtb-study-cldn6-comparison-group-0
    l: mii-exa-mtb-study-cldn6-comparison-group-0

full url:
  v: http://example.org/fhir/EvidenceVariable/mii-exa-mtb-study-cldn6-evidence-variable-0
  l: mii-exa-mtb-study-cldn6-evidence-variable-0
resource: mii-exa-mtb-study-cldn6-evidence-variable-0
request:
  method:
    v: PUT
  url:
    v: EvidenceVariable/mii-exa-mtb-study-cldn6-evidence-variable-0
    l: mii-exa-mtb-study-cldn6-evidence-variable-0

full url:
  v: http://example.org/fhir/Group/mii-exa-mtb-study-cldn6-comparison-group-1
  l: mii-exa-mtb-study-cldn6-comparison-group-1
resource: mii-exa-mtb-study-cldn6-comparison-group-1
request:
  method:
    v: PUT
  url:
    v: Group/mii-exa-mtb-study-cldn6-comparison-group-1
    l: mii-exa-mtb-study-cldn6-comparison-group-1

full url:
  v: http://example.org/fhir/EvidenceVariable/mii-exa-mtb-study-cldn6-evidence-variable-1
  l: mii-exa-mtb-study-cldn6-evidence-variable-1
resource: mii-exa-mtb-study-cldn6-evidence-variable-1
request:
  method:
    v: PUT
  url:
    v: EvidenceVariable/mii-exa-mtb-study-cldn6-evidence-variable-1
    l: mii-exa-mtb-study-cldn6-evidence-variable-1

full url:
  v: http://example.org/fhir/Organization/mii-exa-mtb-study-sponsor-biontech
  l: mii-exa-mtb-study-sponsor-biontech
resource: mii-exa-mtb-study-sponsor-biontech
request:
  method:
    v: PUT
  url:
    v: Organization/mii-exa-mtb-study-sponsor-biontech
    l: mii-exa-mtb-study-sponsor-biontech

full url:
  v: http://example.org/fhir/PractitionerRole/mii-exa-mtb-study-investigator-biontech
  l: mii-exa-mtb-study-investigator-biontech
resource: mii-exa-mtb-study-investigator-biontech
request:
  method:
    v: PUT
  url:
    v: PractitionerRole/mii-exa-mtb-study-investigator-biontech
    l: mii-exa-mtb-study-investigator-biontech

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-0
  l: mii-exa-mtb-study-cldn6-location-0
resource: mii-exa-mtb-study-cldn6-location-0
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-0
    l: mii-exa-mtb-study-cldn6-location-0

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-1
  l: mii-exa-mtb-study-cldn6-location-1
resource: mii-exa-mtb-study-cldn6-location-1
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-1
    l: mii-exa-mtb-study-cldn6-location-1

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-2
  l: mii-exa-mtb-study-cldn6-location-2
resource: mii-exa-mtb-study-cldn6-location-2
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-2
    l: mii-exa-mtb-study-cldn6-location-2

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-3
  l: mii-exa-mtb-study-cldn6-location-3
resource: mii-exa-mtb-study-cldn6-location-3
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-3
    l: mii-exa-mtb-study-cldn6-location-3

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-4
  l: mii-exa-mtb-study-cldn6-location-4
resource: mii-exa-mtb-study-cldn6-location-4
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-4
    l: mii-exa-mtb-study-cldn6-location-4

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-5
  l: mii-exa-mtb-study-cldn6-location-5
resource: mii-exa-mtb-study-cldn6-location-5
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-5
    l: mii-exa-mtb-study-cldn6-location-5

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-6
  l: mii-exa-mtb-study-cldn6-location-6
resource: mii-exa-mtb-study-cldn6-location-6
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-6
    l: mii-exa-mtb-study-cldn6-location-6

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-7
  l: mii-exa-mtb-study-cldn6-location-7
resource: mii-exa-mtb-study-cldn6-location-7
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-7
    l: mii-exa-mtb-study-cldn6-location-7

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-8
  l: mii-exa-mtb-study-cldn6-location-8
resource: mii-exa-mtb-study-cldn6-location-8
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-8
    l: mii-exa-mtb-study-cldn6-location-8

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-9
  l: mii-exa-mtb-study-cldn6-location-9
resource: mii-exa-mtb-study-cldn6-location-9
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-9
    l: mii-exa-mtb-study-cldn6-location-9

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-10
  l: mii-exa-mtb-study-cldn6-location-10
resource: mii-exa-mtb-study-cldn6-location-10
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-10
    l: mii-exa-mtb-study-cldn6-location-10

full url:
  v: http://example.org/fhir/Location/mii-exa-mtb-study-cldn6-location-11
  l: mii-exa-mtb-study-cldn6-location-11
resource: mii-exa-mtb-study-cldn6-location-11
request:
  method:
    v: PUT
  url:
    v: Location/mii-exa-mtb-study-cldn6-location-11
    l: mii-exa-mtb-study-cldn6-location-11

full url:
  v: http://example.org/fhir/ResearchStudy/mii-exa-mtb-study-tedova
  l: mii-exa-mtb-study-tedova
resource: mii-exa-mtb-study-tedova
request:
  method:
    v: PUT
  url:
    v: ResearchStudy/mii-exa-mtb-study-tedova
    l: mii-exa-mtb-study-tedova

full url:
  v: http://example.org/fhir/ServiceRequest/mii-exa-mtb-study-request-tedova
  l: mii-exa-mtb-study-request-tedova
resource: mii-exa-mtb-study-request-tedova
request:
  method:
    v: PUT
  url:
    v: ServiceRequest/mii-exa-mtb-study-request-tedova
    l: mii-exa-mtb-study-request-tedova

full url:
  v: http://example.org/fhir/ResearchStudy/mii-exa-mtb-study-ccne1
  l: mii-exa-mtb-study-ccne1
resource: mii-exa-mtb-study-ccne1
request:
  method:
    v: PUT
  url:
    v: ResearchStudy/mii-exa-mtb-study-ccne1
    l: mii-exa-mtb-study-ccne1

full url:
  v: http://example.org/fhir/ServiceRequest/mii-exa-mtb-study-request-ccne1
  l: mii-exa-mtb-study-request-ccne1
resource: mii-exa-mtb-study-request-ccne1
request:
  method:
    v: PUT
  url:
    v: ServiceRequest/mii-exa-mtb-study-request-ccne1
    l: mii-exa-mtb-study-request-ccne1

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
  l: mii-exa-mtb-medication-request-mirvetuximab
resource: mii-exa-mtb-medication-request-mirvetuximab
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-mirvetuximab
    l: mii-exa-mtb-medication-request-mirvetuximab

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-trastuzumab-deruxtecan
  l: mii-exa-mtb-medication-request-trastuzumab-deruxtecan
resource: mii-exa-mtb-medication-request-trastuzumab-deruxtecan
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-trastuzumab-deruxtecan
    l: mii-exa-mtb-medication-request-trastuzumab-deruxtecan

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-adavosertib
  l: mii-exa-mtb-medication-request-adavosertib
resource: mii-exa-mtb-medication-request-adavosertib
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-adavosertib
    l: mii-exa-mtb-medication-request-adavosertib

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-carboplatin
  l: mii-exa-mtb-medication-request-carboplatin
resource: mii-exa-mtb-medication-request-carboplatin
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-carboplatin
    l: mii-exa-mtb-medication-request-carboplatin

full url:
  v: http://example.org/fhir/RequestGroup/mii-exa-mtb-request-group-adavosertib-carboplatin
  l: mii-exa-mtb-request-group-adavosertib-carboplatin
resource: mii-exa-mtb-request-group-adavosertib-carboplatin
request:
  method:
    v: PUT
  url:
    v: RequestGroup/mii-exa-mtb-request-group-adavosertib-carboplatin
    l: mii-exa-mtb-request-group-adavosertib-carboplatin

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-lunresertib
  l: mii-exa-mtb-medication-request-lunresertib
resource: mii-exa-mtb-medication-request-lunresertib
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-lunresertib
    l: mii-exa-mtb-medication-request-lunresertib

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-camonsertib
  l: mii-exa-mtb-medication-request-camonsertib
resource: mii-exa-mtb-medication-request-camonsertib
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-camonsertib
    l: mii-exa-mtb-medication-request-camonsertib

full url:
  v: http://example.org/fhir/RequestGroup/mii-exa-mtb-request-group-lunresertib-camonsertib
  l: mii-exa-mtb-request-group-lunresertib-camonsertib
resource: mii-exa-mtb-request-group-lunresertib-camonsertib
request:
  method:
    v: PUT
  url:
    v: RequestGroup/mii-exa-mtb-request-group-lunresertib-camonsertib
    l: mii-exa-mtb-request-group-lunresertib-camonsertib

full url:
  v: http://example.org/fhir/MedicationRequest/mii-exa-mtb-medication-request-cobimetinib
  l: mii-exa-mtb-medication-request-cobimetinib
resource: mii-exa-mtb-medication-request-cobimetinib
request:
  method:
    v: PUT
  url:
    v: MedicationRequest/mii-exa-mtb-medication-request-cobimetinib
    l: mii-exa-mtb-medication-request-cobimetinib

full url:
  v: http://example.org/fhir/CarePlan/mii-exa-mtb-kim-musterperson-therapieplan
  l: mii-exa-mtb-kim-musterperson-therapieplan
resource: mii-exa-mtb-kim-musterperson-therapieplan
request:
  method:
    v: PUT
  url:
    v: CarePlan/mii-exa-mtb-kim-musterperson-therapieplan
    l: mii-exa-mtb-kim-musterperson-therapieplan

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-tumorzellgehalt-aszites
  l: mii-exa-mtb-kim-tumorzellgehalt-aszites
resource: mii-exa-mtb-kim-tumorzellgehalt-aszites
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-tumorzellgehalt-aszites
    l: mii-exa-mtb-kim-tumorzellgehalt-aszites

full url:
  v: http://example.org/fhir/ServiceRequest/mii-exa-mtb-kim-humangenetische-beratung-aszites
  l: mii-exa-mtb-kim-humangenetische-beratung-aszites
resource: mii-exa-mtb-kim-humangenetische-beratung-aszites
request:
  method:
    v: PUT
  url:
    v: ServiceRequest/mii-exa-mtb-kim-humangenetische-beratung-aszites
    l: mii-exa-mtb-kim-humangenetische-beratung-aszites

full url:
  v: http://example.org/fhir/ServiceRequest/mii-exa-mtb-kim-histologie-evaluation-aszites
  l: mii-exa-mtb-kim-histologie-evaluation-aszites
resource: mii-exa-mtb-kim-histologie-evaluation-aszites
request:
  method:
    v: PUT
  url:
    v: ServiceRequest/mii-exa-mtb-kim-histologie-evaluation-aszites
    l: mii-exa-mtb-kim-histologie-evaluation-aszites

full url:
  v: http://example.org/fhir/ServiceRequest/mii-exa-mtb-kim-rebiopsie-aszites
  l: mii-exa-mtb-kim-rebiopsie-aszites
resource: mii-exa-mtb-kim-rebiopsie-aszites
request:
  method:
    v: PUT
  url:
    v: ServiceRequest/mii-exa-mtb-kim-rebiopsie-aszites
    l: mii-exa-mtb-kim-rebiopsie-aszites

full url:
  v: http://example.org/fhir/Condition/mii-exa-mtb-kim-diagnose
  l: mii-exa-mtb-kim-diagnose
resource: mii-exa-mtb-kim-diagnose
request:
  method:
    v: PUT
  url:
    v: Condition/mii-exa-mtb-kim-diagnose
    l: mii-exa-mtb-kim-diagnose

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-tumorausbreitung
  l: mii-exa-mtb-kim-tumorausbreitung
resource: mii-exa-mtb-kim-tumorausbreitung
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-tumorausbreitung
    l: mii-exa-mtb-kim-tumorausbreitung

full url:
  v: http://example.org/fhir/Observation/mii-exa-mtb-kim-oncotree
  l: mii-exa-mtb-kim-oncotree
resource: mii-exa-mtb-kim-oncotree
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-mtb-kim-oncotree
    l: mii-exa-mtb-kim-oncotree

full url:
  v: http://example.org/fhir/Condition/PatientKimMusterperson-PrimaryDiagnosis-2
  l: PatientKimMusterperson-PrimaryDiagnosis-2
resource: PatientKimMusterperson-PrimaryDiagnosis-2
request:
  method:
    v: PUT
  url:
    v: Condition/PatientKimMusterperson-PrimaryDiagnosis-2
    l: PatientKimMusterperson-PrimaryDiagnosis-2

full url:
  v: http://example.org/fhir/Observation/mii-exa-onko-allgemeiner-leistungszustand-ecog
  l: mii-exa-onko-allgemeiner-leistungszustand-ecog
resource: mii-exa-onko-allgemeiner-leistungszustand-ecog
request:
  method:
    v: PUT
  url:
    v: Observation/mii-exa-onko-allgemeiner-leistungszustand-ecog
    l: mii-exa-onko-allgemeiner-leistungszustand-ecog

full url:
  v: http://example.org/fhir/Organization/MyHospital
  l: MyHospital
resource: MyHospital
request:
  method:
    v: PUT
  url:
    v: Organization/MyHospital
    l: MyHospital

full url:
  v: http://example.org/fhir/Organization/MyInsurer
  l: MyInsurer
resource: MyInsurer
request:
  method:
    v: PUT
  url:
    v: Organization/MyInsurer
    l: MyInsurer

full url:
  v: http://example.org/fhir/Coverage/MyCoverage
  l: MyCoverage
resource: MyCoverage
request:
  method:
    v: PUT
  url:
    v: Coverage/MyCoverage
    l: MyCoverage

v: Procedure/PatientKimMusterperson-SystemicTherapy-3

l: MTBChemo1Procedure
reference:
  v: Procedure/MTBChemo1Procedure

l: PatientKimMusterperson-Procedure-5
reference:
  v: Procedure/PatientKimMusterperson-Procedure-5

l: PatientKimMusterperson-Observation-20
reference:
  v: Observation/PatientKimMusterperson-Observation-20

l: PatientKimMusterperson-Observation-21
reference:
  v: Observation/PatientKimMusterperson-Observation-21

l: PatientKimMusterperson-Observation-22
reference:
  v: Observation/PatientKimMusterperson-Observation-22

l: PatientKimMusterperson-Observation-23
reference:
  v: Observation/PatientKimMusterperson-Observation-23

l: MTBChemo2Procedure
reference:
  v: Procedure/MTBChemo2Procedure

l: PatientKimMusterperson-Procedure-6
reference:
  v: Procedure/PatientKimMusterperson-Procedure-6

l: PatientKimMusterperson-Observation-24
reference:
  v: Observation/PatientKimMusterperson-Observation-24

l: PatientKimMusterperson-Observation-25
reference:
  v: Observation/PatientKimMusterperson-Observation-25

l: PatientKimMusterperson-Procedure-7
reference:
  v: Procedure/PatientKimMusterperson-Procedure-7

l: PatientKimMusterperson-Observation-26
reference:
  v: Observation/PatientKimMusterperson-Observation-26

l: PatientKimMusterperson-Observation-27
reference:
  v: Observation/PatientKimMusterperson-Observation-27

l: PatientKimMusterperson-Observation-28
reference:
  v: Observation/PatientKimMusterperson-Observation-28

l: PatientKimMusterperson-Observation-29
reference:
  v: Observation/PatientKimMusterperson-Observation-29

l: PatientKimMusterperson-Observation-30
reference:
  v: Observation/PatientKimMusterperson-Observation-30