dQM CMS Content Implementation Guide
2026.1.0 - CI Build

dQM CMS Content Implementation Guide, published by cqframework. This guide is not an authorized publication; it is the continuous build for version 2026.1.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/cqframework/dqm-content-cms-2026/ and changes regularly. See the Directory of published versions

## ValueSet: Strong CYP3A4 Inhibitor Medications

Official URL: https://example.org/fhir/ValueSet/strong-cyp3a4-inhibitors | Version: 1.0.0
Draft as of 2026-06-16 | Computable Name: StrongCYP3A4Inhibitors

RxNorm codes for strong CYP3A4 inhibitors that may interact with atorvastatin, including clarithromycin, HIV protease inhibitors, and itraconazole

References

This value set is not used here; it may be used elsewhere (e.g. specifications and/or implementations that use this content)

### Logical Definition (CLD)

- Include these codes as defined in `http://www.nlm.nih.gov/research/umls/rxnorm` version Not Stated (use latest from terminology server)

  Code | Display
  308460 | Clarithromycin 500 MG Oral Tablet
  200344 | Itraconazole 100 MG Oral Capsule
  349251 | Ketoconazole 200 MG Oral Tablet
  349439 | Ritonavir 100 MG Oral Tablet
  349478 | Indinavir 400 MG Oral Capsule
  349476 | Saquinavir 200 MG Oral Capsule
  359906 | Nelfinavir 250 MG Oral Tablet

### Expansion

Expansion from tx.fhir.org based on codesystem RxNorm version 03022026

This value set contains 6 concepts

System | Code | Display (en) | Inactive | status | JSON | XML
`http://www.nlm.nih.gov/research/umls/rxnorm` | 308460 | azithromycin 250 MG Oral Tablet |  |  |  |
`http://www.nlm.nih.gov/research/umls/rxnorm` | 200344 | hydroxyurea 400 MG Oral Capsule |  |  |  |
`http://www.nlm.nih.gov/research/umls/rxnorm` | 349251 | tenofovir disoproxil fumarate 300 MG Oral Tablet |  |  |  |
`http://www.nlm.nih.gov/research/umls/rxnorm` | 349478 | vardenafil 5 MG Oral Tablet |  |  |  |
`http://www.nlm.nih.gov/research/umls/rxnorm` | 349476 | Folic Acid 1 MG / Iron 12 MG Oral Tablet | inactive | archived |  |
`http://www.nlm.nih.gov/research/umls/rxnorm` | 359906 | phenylephrine hydrochloride 1.5 MG/ML Oral Suspension |  |  |  |

Explanation of the columns that may appear on this page:

Level | A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System | The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code | The code (used as the code in the resource instance)
Display | The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition | An explanation of the meaning of the concept
Comments | Additional notes about how to use the code