Genomics Reporting Implementation Guide
4.0.0-cibuild - CI Build

Genomics Reporting Implementation Guide, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 4.0.0-cibuild built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/genomics-reporting/ and changes regularly. See the Directory of published versions

## : ClinVar Evidence Level Example Codes - XML Representation

Page standards status: Informative

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    <CodeSystem xmlns="http://hl7.org/fhir">
      <id value="clinvar-evidence-level-custom-cs"/>
      <text>
        <status value="generated"/>
        <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: CodeSystem clinvar-evidence-level-custom-cs</b></p><a name="clinvar-evidence-level-custom-cs"> </a><a name="hcclinvar-evidence-level-custom-cs"> </a><p>This case-sensitive code system <code>http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs</code> defines the following codes:</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style="white-space:nowrap">4-star<a name="clinvar-evidence-level-custom-cs-4-star"> </a></td><td>4 star</td><td>Supported by practice guideline</td></tr><tr><td style="white-space:nowrap">3-star<a name="clinvar-evidence-level-custom-cs-3-star"> </a></td><td>3 star</td><td>Supported by expert panel review</td></tr><tr><td style="white-space:nowrap">2-star<a name="clinvar-evidence-level-custom-cs-2-star"> </a></td><td>2 star</td><td>Supported by submission by multiple-submitters with documentation of criteria for assertion</td></tr><tr><td style="white-space:nowrap">1-star<a name="clinvar-evidence-level-custom-cs-1-star"> </a></td><td>1 star</td><td>Single submitter providing interpretation and documentation of criteria for assertion</td></tr><tr><td style="white-space:nowrap">no-star<a name="clinvar-evidence-level-custom-cs-no-star"> </a></td><td>no star</td><td>submitted, no evidence</td></tr></table></div>
      </text>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
        <valueCode value="cg"/>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
        <valueCode value="informative">
          <extension
                     url="http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom">
            <valueCanonical
                            value="http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"/>
          </extension>
        </valueCode>
      </extension>
      <url
           value="http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs"/>
      <version value="4.0.0-cibuild"/>
      <name value="ClinVarEvidenceLevelCustomCS"/>
      <title value="ClinVar Evidence Level Example Codes"/>
      <status value="active"/>
      <experimental value="true"/>
      <date value="2025-11-08T00:09:50+00:00"/>
      <publisher value="HL7 International / Clinical Genomics"/>
      <contact>
        <name value="HL7 International / Clinical Genomics"/>
        <telecom>
          <system value="url"/>
          <value value="http://www.hl7.org/Special/committees/clingenomics"/>
        </telecom>
        <telecom>
          <system value="email"/>
          <value value="cg@lists.HL7.org"/>
        </telecom>
      </contact>
      <description
                   value="ClinVar contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on  ClinVar https://www.ncbi.nlm.nih.gov/clinvar/docs/review_status/ . These examples are informational only, for copyright information contact the relevant source."/>
      <jurisdiction>
        <coding>
          <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
          <code value="001"/>
          <display value="World"/>
        </coding>
      </jurisdiction>
      <caseSensitive value="true"/>
      <content value="complete"/>
      <count value="5"/>
      <concept>
        <code value="4-star"/>
        <display value="4 star"/>
        <definition value="Supported by practice guideline"/>
      </concept>
      <concept>
        <code value="3-star"/>
        <display value="3 star"/>
        <definition value="Supported by expert panel review"/>
      </concept>
      <concept>
        <code value="2-star"/>
        <display value="2 star"/>
        <definition
                    value="Supported by submission by multiple-submitters with documentation of criteria for assertion"/>
      </concept>
      <concept>
        <code value="1-star"/>
        <display value="1 star"/>
        <definition
                    value="Single submitter providing interpretation and documentation of criteria for assertion"/>
      </concept>
      <concept>
        <code value="no-star"/>
        <display value="no star"/>
        <definition value="submitted, no evidence"/>
      </concept>
    </CodeSystem>