Genomics Reporting Implementation Guide
4.0.0-cibuild - CI Build

Genomics Reporting Implementation Guide, published by HL7 International / Clinical Genomics. This guide is not an authorized publication; it is the continuous build for version 4.0.0-cibuild built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/genomics-reporting/ and changes regularly. See the Directory of published versions

## Example DiagnosticReport: PGxGenomicReportEMERGE

Page standards status: Informative

Profile: Genomic Report

## Genetic analysis report (Genetics)

Subject | Adam B. Everyman Male, DoB: 1951-01-20 ( Medical Record Number: m123 (use: usual, ))
When For | 2020-01-01 00:00:00-0500
Reported | 2020-01-01 00:00:00-0500
Performer | Organization some lab

Report Details

Code | Value | Flags | Note | When For
Therapeutic Implication |  | Final |  | 2019-04-01
Therapeutic Implication |  | Final |  | 2019-04-01
Therapeutic Implication |  | Final |  | 2019-04-01
Therapeutic Implication |  | Final |  | 2019-04-01
Therapeutic Implication |  | Final |  | 2019-04-01
Therapeutic Implication |  | Final |  | 2019-04-01
Genotype display name | CYP2C19*2/*2 | Final |  | 2019-04-01
Genotype display name | VKORC1 rs9923231 C/T | Final |  | 2019-04-01
Genotype display name | CYP2C9*1/*1 | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2020-01-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final |  | 2019-04-01
Genetic variant assessment | Present | Final | This variant was confirmed with SANGER sequencing | 2019-04-01
Genetic variant assessment | Present | Final | This variant was confirmed with SANGER sequencing | 2019-04-01
Genetic variant assessment | Present | Final | This variant was confirmed with SANGER sequencing | 2019-04-01

Based on the genotype result, this patient is predicted to have a CYP2C19 poor metabolizer phenotype. This genotype information can be used by patients and clinicians as part of the shared decision-making process for several drugs metabolized by CYP2C19 including clopidogrel, voriconazole, amitriptyline, citalopram and escitalopram.

Coded Conclusions:

- Positive