#1

GET https://tx.fhir.org/r5/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4221
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637728

{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20250821042601.640Z. Server version 3.8.7 built 20250821042601.640Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.7.8"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-3.8.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-10-16T23:40:34.029Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "3.8.7","releaseDate" : "2025-08-21T04:26:01.640Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}

#2

GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:133329
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637729

{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r5/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2025-10-16T23:40:34.123Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "5.0.0"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/account-aggregate","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-balance-term","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-billing-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-function","version" : [{"code" : 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"urn:iso:std:iso:3166","version" : [{"code" : "20210120"}]},{"uri" : "urn:iso:std:iso:4217"},{"uri" : "urn:iso-astm:E1762-95:2013","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1001.101.104.16592","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1005.17"},{"uri" : "urn:oid:2.16.840.1.113883.2.9.6.2.7","version" : [{"code" : "ISCO-08"}]},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8"},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8","version" : [{"code" : "5.0.0"}]}],"expansion" : {"parameter" : [{"name" : "cache-id","documentation" : "This server supports caching terminology resources between calls. Clients only need to send value sets and codesystems once; there after they are automatically in scope for calls with the same cache-id. The cache is retained for 30 min from last call"},{"name" : "tx-resource","documentation" : "Additional valuesets needed for evaluation e.g. value sets referred to from the import statement of the value set being expanded"},{"name" : "_incomplete"},{"name" : "abstract"},{"name" : "activeOnly"},{"name" : "check-system-version"},{"name" : "count"},{"name" : "default-to-latest-version"},{"name" : "displayLanguage"},{"name" : "excludeNested"},{"name" : "excludeNotForUI"},{"name" : "excludePostCoordinated"},{"name" : "force-system-version"},{"name" : "inactive"},{"name" : "includeAlternateCodes"},{"name" : "includeDefinition"},{"name" : "includeDesignations"},{"name" : "incomplete-ok"},{"name" : "limitedExpansion"},{"name" : "mode","documentation" : "=lenient-display-validation"},{"name" : "no-cache"},{"name" : "offset"},{"name" : "profile"},{"name" : "property"},{"name" : "system-version"},{"name" : "valueSetMode","documentation" : "= CHECK_MEMBERSHIP_ONLY | NO_MEMBERSHIP_CHECK"}]}}

#3

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1733
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637758

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#4

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1747
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637760

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#5

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1754
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637762

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#6

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637764

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#7

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30102-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:810
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637766

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30102-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#8

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637768

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#9

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637770

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#10

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637772

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#11

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637774

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#12

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1585
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637776

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#13

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637778

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#14

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:44 GMT
last-modified:Thu, 16 Oct 2025 23:40:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637780

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#15

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637782

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#16

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637784

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#17

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637786

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#18

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637788

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#19

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637790

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#20

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637792

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#21

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637794

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#22

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637796

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#23

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637798

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#24

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637800

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#25

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637802

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#26

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:45 GMT
last-modified:Thu, 16 Oct 2025 23:40:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637804

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#27

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637806

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#28

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637808

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#29

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637810

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#30

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637812

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#31

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637814

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#32

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637816

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#33

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637818

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#34

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637822

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#35

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637824

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#36

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637827

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#37

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637829

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#38

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637831

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#39

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:46 GMT
last-modified:Thu, 16 Oct 2025 23:40:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637833

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#40

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637835

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#41

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637837

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#42

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637839

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#43

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637841

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#44

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637843

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#45

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637846

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#46

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637848

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#47

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637851

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#48

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637853

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#49

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637855

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#50

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637857

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#51

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637859

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#52

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:47 GMT
last-modified:Thu, 16 Oct 2025 23:40:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637861

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#53

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637863

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#54

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637865

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#55

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637867

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#56

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637869

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#57

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637871

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#58

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637873

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#59

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637875

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#60

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637877

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#61

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637879

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#62

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637881

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#63

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637883

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#64

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637885

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#65

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:48 GMT
last-modified:Thu, 16 Oct 2025 23:40:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637887

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#66

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637889

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#67

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637891

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#68

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637893

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#69

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637895

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#70

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637897

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#71

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637899

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#72

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637901

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#73

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637903

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#74

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637905

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#75

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637907

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#76

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637909

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#77

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637911

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#78

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:49 GMT
last-modified:Thu, 16 Oct 2025 23:40:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637913

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#79

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637915

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#80

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637917

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#81

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637919

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#82

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:804
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637921

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#83

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:799
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637923

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#84

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637926

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#85

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:810
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637928

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#86

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637930

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#87

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637932

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#88

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637934

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#89

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637936

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#90

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:50 GMT
last-modified:Thu, 16 Oct 2025 23:40:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637938

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#91

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:804
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637940

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#92

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:895
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637942

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#93

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:809
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637944

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#94

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1626
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637946

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#95

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:797
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637948

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#96

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637950

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#97

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:810
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637952

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#98

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:879
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637954

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#99

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:793
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:51 GMT
last-modified:Thu, 16 Oct 2025 23:40:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637956

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#100

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637958

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#101

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637960

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#102

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:811
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637962

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#103

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637964

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#104

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:791
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637966

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#105

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:823
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637968

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#106

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"%"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:795
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637970

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "%"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "%"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#% (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#%\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#107

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:796
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637972

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#108

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:795
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637974

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#109

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637976

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#110

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637978

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81301-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#111

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637980

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#112

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:823
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:52 GMT
last-modified:Thu, 16 Oct 2025 23:40:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637982

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#113

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:798
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637984

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#114

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637986

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#115

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:867
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637988

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#116

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:886
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637990

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#117

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637992

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#118

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637994

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#119

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637996

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#120

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:809
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2637998

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#121

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51969-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638000

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#122

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1550
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:53 GMT
last-modified:Thu, 16 Oct 2025 23:40:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638002

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#123

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638004

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#124

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638006

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#125

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638008

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "version","valueString" : "137"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP|137\"\r\n"}]}

#126

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81299-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638010

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81299-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#127

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81300-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638012

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81300-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#128

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638014

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#129

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638016

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#130

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1550
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638018

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#131

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1/1000000"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:827
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638020

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1/1000000"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1/1000000"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#1/1000000 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#1/1000000\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#132

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638022

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.31.0)\" (content = complete)\r\n"}]}

#133

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:54 GMT
last-modified:Thu, 16 Oct 2025 23:40:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638024

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#134

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638026

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#135

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638028

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#136

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:879
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638030

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#137

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638032

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#138

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:890
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638034

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#139

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:882
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638036

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#140

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:55 GMT
last-modified:Thu, 16 Oct 2025 23:40:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638038

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#141

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638040

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#142

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:890
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638042

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#143

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:795
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638046

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#144

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1607
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638050

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#145

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638052

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#146

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1617
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638055

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#147

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638058

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#148

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638060

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#149

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638063

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#150

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1795
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:56 GMT
last-modified:Thu, 16 Oct 2025 23:40:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638065

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}

#151

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1696
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638068

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#152

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638070

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#153

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:918
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638072

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#154

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:849
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638074

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48000-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#155

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638076

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000003.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#156

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:962
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638078

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#157

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:886
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638080

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#158

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:57 GMT
last-modified:Thu, 16 Oct 2025 23:40:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638082

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#159

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638084

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#160

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638086

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#161

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:817
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638088

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#162

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:826
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638090

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94186-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#163

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638092

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82309-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#164

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638094

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#165

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638096

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#166

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638098

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#167

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638100

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#168

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638102

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#169

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638104

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX,t(9;22)(q34;q4)"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX,t(9;22)(q34;q4) (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX,t(9;22)(q34;q4)\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#170

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1482
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:58 GMT
last-modified:Thu, 16 Oct 2025 23:40:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638106

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#171

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638108

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#172

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638110

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#173

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638112

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#174

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638114

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#175

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638116

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000009.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#176

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638118

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#177

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:879
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638120

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#178

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:867
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:40:59 GMT
last-modified:Thu, 16 Oct 2025 23:40:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638122

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#179

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638124

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#180

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638126

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#181

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638128

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#182

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:859
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638130

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#183

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:867
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638132

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#184

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638134

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#185

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:954
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638136

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#186

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:00 GMT
last-modified:Thu, 16 Oct 2025 23:41:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638138

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000023.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#187

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638140

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#188

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:791
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638142

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#189

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638144

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000017.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#190

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30100-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638146

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30100-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#191

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1585
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638148

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#192

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:863
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638150

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#193

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638152

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#194

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638154

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#195

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:01 GMT
last-modified:Thu, 16 Oct 2025 23:41:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638156

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000016.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#196

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:02 GMT
last-modified:Thu, 16 Oct 2025 23:41:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638158

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#197

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:02 GMT
last-modified:Thu, 16 Oct 2025 23:41:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638160

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#198

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:02 GMT
last-modified:Thu, 16 Oct 2025 23:41:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638162

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#199

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:02 GMT
last-modified:Thu, 16 Oct 2025 23:41:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638164

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#200

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1689
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:02 GMT
last-modified:Thu, 16 Oct 2025 23:41:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638167

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#201

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA26421-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:822
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:03 GMT
last-modified:Thu, 16 Oct 2025 23:41:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638169

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26421-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#202

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:379
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:03 GMT
server:nginx
x-request-id:238-2638172

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}

#203

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:379
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:03 GMT
server:nginx
x-request-id:238-2638175

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}

#204

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1557
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:03 GMT
last-modified:Thu, 16 Oct 2025 23:41:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638177

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002072\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#205

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1557
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:03 GMT
last-modified:Thu, 16 Oct 2025 23:41:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638181

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#206

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]}]}}}]}
200
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connection:keep-alive
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:03 GMT
last-modified:Thu, 16 Oct 2025 23:41:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638183

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:647b65f0-1bcb-41cc-a8e4-255b9dbe8149","timestamp" : "2025-10-16T23:41:03.993Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}

#207

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}
200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:04 GMT
last-modified:Thu, 16 Oct 2025 23:41:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638186

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:9b14e3a8-9d5c-4cf3-b610-04ecf2425475","timestamp" : "2025-10-16T23:41:04.086Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "version","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}

#208

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://loinc.org","concept":[{"code":"85337-4","display":"Estrogen receptor Ag Immune stain Ql (Breast cancer specimen)"},{"code":"72382-5","display":"HER2 IA Qn (Tiss)"},{"code":"77637-7","display":"HLA-A and B and C (class I) IgG panel IA [Identifier]"},{"code":"40557-1","display":"Progesterone receptor Ag Immune stain Ql (Tiss)"},{"code":"85147-7","display":"PD-L1 by clone 22C3 Immune stain Doc (Tiss)"},{"code":"59025-7","display":"Neutrophil Ab FC Qn (S)"},{"code":"59003-4","display":"Lactoferrin Ab IA Qn (S)"},{"code":"10495-0","display":"Insulin Ag Immune stain Ql (Tiss)"},{"code":"16550-6","display":"Carbohydrates Nom (U)"},{"code":"2569-2","display":"Lipids (S) [Mass/Vol]"},{"code":"4551-8","display":"Hemoglobin A2 (Bld) [Mass fraction]"},{"code":"19195-7","display":"Prostate specific Ag Qn"},{"code":"64083-9","display":"MGMT gene methylation score Molgen (Tiss) [Ratio]"},{"code":"62862-8","display":"Microsatellite instability Immune stain Ql (Tiss)"},{"code":"81704-9","display":"Microsatellite instability marker D17S250 Ql (Cancer specimen)"},{"code":"94077-5","display":"Tumor mutation burden Ql (Tumor) [Interp]"}]}]}}}]}
200
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cache-control:public, max-age=600
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:04 GMT
last-modified:Thu, 16 Oct 2025 23:41:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638189

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:fc10920d-6ada-4021-ae5d-2b3d6f2db3bb","timestamp" : "2025-10-16T23:41:04.144Z","total" : 16,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "85337-4","display" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"system" : "http://loinc.org","code" : "77637-7","display" : "HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"},{"system" : "http://loinc.org","code" : "40557-1","display" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"system" : "http://loinc.org","code" : "59025-7","display" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"},{"system" : "http://loinc.org","code" : "59003-4","display" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"},{"system" : "http://loinc.org","code" : "10495-0","display" : "Insulin Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "16550-6","display" : "Carbohydrates [Identifier] in Urine"},{"system" : "http://loinc.org","code" : "2569-2","display" : "Lipids [Mass/volume] in Serum"},{"system" : "http://loinc.org","code" : "4551-8","display" : "Hemoglobin A2/Hemoglobin.total in Blood"},{"system" : "http://loinc.org","code" : "19195-7","display" : "Prostate specific Ag [Units/volume] in Serum or Plasma"},{"system" : "http://loinc.org","code" : "64083-9","display" : "MGMT gene methylation score in Tissue by Molecular genetics method"},{"system" : "http://loinc.org","code" : "62862-8","display" : "Microsatellite instability [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "81704-9","display" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"},{"system" : "http://loinc.org","code" : "94077-5","display" : "Tumor mutation burden [Interpretation]"}]}}

#209

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C120465","display":"Homologous Recombination Repair Deficiency"}]}]}}}]}
422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:04 GMT
server:nginx
x-request-id:238-2638194

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#210

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-biomarker-code-vs-inc-1","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C120465","display":"Homologous Recombination Repair Deficiency"}]}]}}}]}
422
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date:Thu, 16 Oct 2025 23:41:04 GMT
server:nginx
x-request-id:238-2638197

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#211

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1564
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:04 GMT
last-modified:Thu, 16 Oct 2025 23:41:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638201

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001537\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#212

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"jurisdiction","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"vocab"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"deprecated"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/jurisdiction","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.48"}],"version":"6.0.0-ballot3","name":"JurisdictionValueSet","title":"Jurisdiction ValueSet","status":"draft","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International / Terminology Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]},{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/Vocab"}]}],"description":"This value set defines a base set of codes for country, country subdivision and region    for indicating where a resource is intended to be used.   \r\n   \r\n   Note: The codes for countries and country subdivisions are taken from    [ISO 3166](https://www.iso.org/iso-3166-country-codes.html)    while the codes for \"supra-national\" regions are from    [UN Standard country or area codes for statistical use (M49)](http://unstats.un.org/unsd/methods/m49/m49.htm).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:iso:std:iso:3166"},{"system":"urn:iso:std:iso:3166:-2"},{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","filter":[{"property":"class","op":"=","value":"region"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:41:04 GMT
last-modified:Thu, 16 Oct 2025 23:41:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638209

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unstats.un.org/unsd/methods/m49/m49.htm"},{"name" : "code","valueCode" : "001"},{"name" : "display","valueString" : "World"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm","code" : "001","display" : "World"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "MSG_DEPRECATED"}],"severity" : "information","code" : "business-rule","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "status-check"}],"text" : "Reference to deprecated ValueSet http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166:-2|2021 (from fhir.tx.support.r4#0.31.0)\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"http://unstats.un.org/unsd/methods/m49/m49.htm|\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Validate \"[http://unstats.un.org/unsd/methods/m49/m49.htm#001 (\"World\")]\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Check \"http://unstats.un.org/unsd/methods/m49/m49.htm#001\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: http://unstats.un.org/unsd/methods/m49/m49.htm| for http://unstats.un.org/unsd/methods/m49/m49.htm\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Filter \"class = region\": Code \"001\" found in http://unstats.un.org/unsd/methods/m49/m49.htm|\r\n"}]}

#213

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1553
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:04 GMT
last-modified:Thu, 16 Oct 2025 23:41:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638219

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002072\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#214

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1553
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638222

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#215

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10315-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:817
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638227

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10315-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Ultrarapid metabolizer"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA10315-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA10315-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#216

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25391-6"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25390-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10317-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9657-3"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19542-2"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19541-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6676-6"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6677-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9660-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9661-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6682-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6675-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6674-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9662-3"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25392-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25393-2"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25395-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25394-0"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:5840
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638229

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10317-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Intermediate metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9660-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9661-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6682-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Unknown Significance"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6675-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6674-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9662-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed non-responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25392-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25393-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25395-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Decreased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25394-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor function"}]}}]}

#217

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fsnomed.info%2Fsct HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:238
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638234

{"resourceType" : "Bundle","id" : "db206f96-638e-41ea-9168-058cb0bbdf","meta" : {"lastUpdated" : "2025-10-16T23:41:05.398Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://snomed.info/sct"}]}

#218

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"444734003"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:983
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638237

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#444734003 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#444734003\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#219

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"399223003"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:459
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638240

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"}]}}]}

#220

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85337-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:862
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638250

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85337-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#85337-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#85337-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#221

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"72382-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"77637-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"40557-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85147-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"59025-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"59003-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"10495-0"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"16550-6"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"2569-2"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"4551-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"19195-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"64083-9"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62862-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81704-9"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94077-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:5416
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638252

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "72382-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "77637-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "40557-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "59025-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "59003-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "10495-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Insulin Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "16550-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Carbohydrates [Identifier] in Urine"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "2569-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Lipids [Mass/volume] in Serum"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "4551-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Hemoglobin A2/Hemoglobin.total in Blood"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "19195-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Prostate specific Ag [Units/volume] in Serum or Plasma"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "64083-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MGMT gene methylation score in Tissue by Molecular genetics method"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62862-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81704-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94077-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Tumor mutation burden [Interpretation]"}]}}]}

#222

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C120465"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1775
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:05 GMT
last-modified:Thu, 16 Oct 2025 23:41:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638257

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C120465"},{"name" : "message","valueString" : "Unknown Code 'C120465' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C120465' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120465 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120465\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.31.0)\" (content = fragment)\r\n"}]}

#223

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1560
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:06 GMT
last-modified:Thu, 16 Oct 2025 23:41:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638259

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001537\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#224

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
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#225

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#226

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#227

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#228

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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date:Thu, 16 Oct 2025 23:41:08 GMT
last-modified:Thu, 16 Oct 2025 23:41:08 GMT
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server:nginx
x-request-id:238-2638274

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "5792-7"},{"name" : "message","valueString" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Parameters: disp-lang=en-US, membership-only, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Validate \"[http://loinc.org#5792-7 (\"\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Check \"http://loinc.org#5792-7\"\r\n"}]}

#229

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:915
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:08 GMT
last-modified:Thu, 16 Oct 2025 23:41:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638276

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#230

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:931
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:08 GMT
last-modified:Thu, 16 Oct 2025 23:41:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638279

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#231

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:946
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:08 GMT
last-modified:Thu, 16 Oct 2025 23:41:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638281

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#232

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48000-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:969
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:09 GMT
last-modified:Thu, 16 Oct 2025 23:41:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638284

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48000-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48000-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#233

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:936
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:10 GMT
last-modified:Thu, 16 Oct 2025 23:41:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638286

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#234

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fdicom.nema.org%2Fmedical%2Fdicom%2Fcurrent%2Foutput%2Fchtml%2Fpart16%2Fsect_CID_33.html HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4699
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638288

{"resourceType" : "Bundle","id" : "12dd6139-a62b-4f42-b195-ff9df3d63f","meta" : {"lastUpdated" : "2025-10-16T23:41:10.858Z"},"type" : "searchset","total" : 1,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html"}],"entry" : [{"fullUrl" : "http://tx.fhir.org/r5/ValueSet/dicom-cid-33-Modality","resource" : {"resourceType" : "ValueSet","id" : "dicom-cid-33-Modality","url" : "http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:1.2.840.10008.6.1.1283"}],"version" : "2025.3.20250714","name" : "Modality","status" : "active","experimental" : false,"date" : "2025-07-14","publisher" : "NEMA MITA DICOM","description" : "Transitive closure of CID 33 Modality","copyright" : "© 2025 NEMA","compose" : {"include" : [{"system" : "http://dicom.nema.org/resources/ontology/DCM","concept" : [{"code" : "BMD","display" : "Bone Mineral Densitometry"},{"code" : "SM","display" : "Slide Microscopy"},{"code" : "EOG","display" : "Electrooculography"},{"code" : "SR","display" : "Structured Report Document"},{"code" : "FID","display" : "Spatial Fiducials"},{"code" : "OP","display" : "Ophthalmic Photography"},{"code" : "OT","display" : "Other Modality"},{"code" : "KO","display" : "Key Object Selection"},{"code" : "GM","display" : "General Microscopy"},{"code" : "ECG","display" : "Electrocardiography"},{"code" : "XA","display" : "X-Ray Angiography"},{"code" : "IOL","display" : "Intraocular Lens Calculation"},{"code" : "XC","display" : "External-camera Photography"},{"code" : "ASMT","display" : "Content Assessment Result"},{"code" : "DMS","display" : "Dermoscopy"},{"code" : "IVUS","display" : "Intravascular Ultrasound"},{"code" : "CR","display" : "Computed Radiography"},{"code" : "CT","display" : "Computed Tomography"},{"code" : "PA","display" : "Photoacoustic"},{"code" : "OSS","display" : "Optical Surface Scanner"},{"code" : "TG","display" : "Thermography"},{"code" : "REG","display" : "Registration"},{"code" : "LEN","display" : "Lensometry"},{"code" : "TEXTUREMAP","display" : "Texture Map"},{"code" : "RTDOSE","display" : "RT Dose"},{"code" : "OPTENF","display" : "Ophthalmic Tomography En Face"},{"code" : "HC","display" : "Hard Copy"},{"code" : "RTPLAN","display" : "RT Plan"},{"code" : "HD","display" : "Hemodynamic"},{"code" : "OCT","display" : "Optical Coherence Tomography"},{"code" : "BDUS","display" : "Ultrasound Bone Densitometry"},{"code" : "M3D","display" : "3D Manufacturing Modeling System"},{"code" : "DG","display" : "Diaphanography"},{"code" : "PR","display" : "Presentation State"},{"code" : "PT","display" : "Positron emission tomography"},{"code" : "LS","display" : "Laser surface scan"},{"code" : "EPS","display" : "Cardiac Electrophysiology"},{"code" : "PX","display" : "Panoramic X-Ray"},{"code" : "OPM","display" : "Ophthalmic Mapping"},{"code" : "OPTBSV","display" : "Ophthalmic Tomography B-scan Volume Analysis"},{"code" : "OPV","display" : "Ophthalmic Visual Field"},{"code" : "DX","display" : "Digital Radiography"},{"code" : "OPT","display" : "Ophthalmic Tomography"},{"code" : "DOC","display" : "Document"},{"code" : "RTRECORD","display" : "RT Treatment Record"},{"code" : "MG","display" : "Mammography"},{"code" : "US","display" : "Ultrasound"},{"code" : "IVOCT","display" : "Intravascular Optical Coherence Tomography"},{"code" : "EMG","display" : "Electromyography"},{"code" : "RTSTRUCT","display" : "RT Structure Set"},{"code" : "MR","display" : "Magnetic Resonance"},{"code" : "IO","display" : "Intra-oral Radiography"},{"code" : "EEG","display" : "Electroencephalography"},{"code" : "RTIMAGE","display" : "RT Image"},{"code" : "VA","display" : "Visual Acuity"},{"code" : "RESP","display" : "Respiratory"},{"code" : "ES","display" : "Endoscopy"},{"code" : "RWV","display" : "Real World Value Map"},{"code" : "AR","display" : "Autorefraction"},{"code" : "POS","display" : "Position Sensor"},{"code" : "SEG","display" : "Segmentation"},{"code" : "RG","display" : "Radiographic imaging"},{"code" : "RF","display" : "Radiofluoroscopy"},{"code" : "AU","display" : "Audio"},{"code" : "KER","display" : "Keratometry"},{"code" : "SMR","display" : "Stereometric Relationship"},{"code" : "CTPROTOCOL","display" : "CT Protocol"},{"code" : "STAIN","display" : "Automated Slide Stainer"},{"code" : "OAM","display" : "Ophthalmic Axial Measurements"},{"code" : "NM","display" : "Nuclear Medicine"},{"code" : "PLAN","display" : "Plan"},{"code" : "BI","display" : "Biomagnetic Imaging"},{"code" : "SRF","display" : "Subjective Refraction"},{"code" : "CFM","display" : "Confocal Microscopy"}]}]}}}]}

#235

GET https://tx.fhir.org/r5/ValueSet/dicom-cid-33-Modality HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4308
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638289

{"resourceType" : "ValueSet","id" : "dicom-cid-33-Modality","url" : "http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:1.2.840.10008.6.1.1283"}],"version" : "2025.3.20250714","name" : "Modality","status" : "active","experimental" : false,"date" : "2025-07-14","publisher" : "NEMA MITA DICOM","description" : "Transitive closure of CID 33 Modality","copyright" : "© 2025 NEMA","compose" : {"include" : [{"system" : "http://dicom.nema.org/resources/ontology/DCM","concept" : [{"code" : "BMD","display" : "Bone Mineral Densitometry"},{"code" : "SM","display" : "Slide Microscopy"},{"code" : "EOG","display" : "Electrooculography"},{"code" : "SR","display" : "Structured Report Document"},{"code" : "FID","display" : "Spatial Fiducials"},{"code" : "OP","display" : "Ophthalmic Photography"},{"code" : "OT","display" : "Other Modality"},{"code" : "KO","display" : "Key Object Selection"},{"code" : "GM","display" : "General Microscopy"},{"code" : "ECG","display" : "Electrocardiography"},{"code" : "XA","display" : "X-Ray Angiography"},{"code" : "IOL","display" : "Intraocular Lens Calculation"},{"code" : "XC","display" : "External-camera Photography"},{"code" : "ASMT","display" : "Content Assessment Result"},{"code" : "DMS","display" : "Dermoscopy"},{"code" : "IVUS","display" : "Intravascular Ultrasound"},{"code" : "CR","display" : "Computed Radiography"},{"code" : "CT","display" : "Computed Tomography"},{"code" : "PA","display" : "Photoacoustic"},{"code" : "OSS","display" : "Optical Surface Scanner"},{"code" : "TG","display" : "Thermography"},{"code" : "REG","display" : "Registration"},{"code" : "LEN","display" : "Lensometry"},{"code" : "TEXTUREMAP","display" : "Texture Map"},{"code" : "RTDOSE","display" : "RT Dose"},{"code" : "OPTENF","display" : "Ophthalmic Tomography En Face"},{"code" : "HC","display" : "Hard Copy"},{"code" : "RTPLAN","display" : "RT Plan"},{"code" : "HD","display" : "Hemodynamic"},{"code" : "OCT","display" : "Optical Coherence Tomography"},{"code" : "BDUS","display" : "Ultrasound Bone Densitometry"},{"code" : "M3D","display" : "3D Manufacturing Modeling System"},{"code" : "DG","display" : "Diaphanography"},{"code" : "PR","display" : "Presentation State"},{"code" : "PT","display" : "Positron emission tomography"},{"code" : "LS","display" : "Laser surface scan"},{"code" : "EPS","display" : "Cardiac Electrophysiology"},{"code" : "PX","display" : "Panoramic X-Ray"},{"code" : "OPM","display" : "Ophthalmic Mapping"},{"code" : "OPTBSV","display" : "Ophthalmic Tomography B-scan Volume Analysis"},{"code" : "OPV","display" : "Ophthalmic Visual Field"},{"code" : "DX","display" : "Digital Radiography"},{"code" : "OPT","display" : "Ophthalmic Tomography"},{"code" : "DOC","display" : "Document"},{"code" : "RTRECORD","display" : "RT Treatment Record"},{"code" : "MG","display" : "Mammography"},{"code" : "US","display" : "Ultrasound"},{"code" : "IVOCT","display" : "Intravascular Optical Coherence Tomography"},{"code" : "EMG","display" : "Electromyography"},{"code" : "RTSTRUCT","display" : "RT Structure Set"},{"code" : "MR","display" : "Magnetic Resonance"},{"code" : "IO","display" : "Intra-oral Radiography"},{"code" : "EEG","display" : "Electroencephalography"},{"code" : "RTIMAGE","display" : "RT Image"},{"code" : "VA","display" : "Visual Acuity"},{"code" : "RESP","display" : "Respiratory"},{"code" : "ES","display" : "Endoscopy"},{"code" : "RWV","display" : "Real World Value Map"},{"code" : "AR","display" : "Autorefraction"},{"code" : "POS","display" : "Position Sensor"},{"code" : "SEG","display" : "Segmentation"},{"code" : "RG","display" : "Radiographic imaging"},{"code" : "RF","display" : "Radiofluoroscopy"},{"code" : "AU","display" : "Audio"},{"code" : "KER","display" : "Keratometry"},{"code" : "SMR","display" : "Stereometric Relationship"},{"code" : "CTPROTOCOL","display" : "CT Protocol"},{"code" : "STAIN","display" : "Automated Slide Stainer"},{"code" : "OAM","display" : "Ophthalmic Axial Measurements"},{"code" : "NM","display" : "Nuclear Medicine"},{"code" : "PLAN","display" : "Plan"},{"code" : "BI","display" : "Biomagnetic Imaging"},{"code" : "SRF","display" : "Subjective Refraction"},{"code" : "CFM","display" : "Confocal Microscopy"}]}]}}

#236

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:11 GMT
last-modified:Thu, 16 Oct 2025 23:41:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638294

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#237

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:926
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:11 GMT
last-modified:Thu, 16 Oct 2025 23:41:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638300

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#238

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:919
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:12 GMT
last-modified:Thu, 16 Oct 2025 23:41:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638306

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#239

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:924
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:14 GMT
last-modified:Thu, 16 Oct 2025 23:41:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638311

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#240

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:932
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:14 GMT
last-modified:Thu, 16 Oct 2025 23:41:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638313

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#241

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:930
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:14 GMT
last-modified:Thu, 16 Oct 2025 23:41:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638315

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#242

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:14 GMT
last-modified:Thu, 16 Oct 2025 23:41:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638319

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#243

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:15 GMT
last-modified:Thu, 16 Oct 2025 23:41:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638321

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#244

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:924
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:15 GMT
last-modified:Thu, 16 Oct 2025 23:41:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638323

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#245

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:931
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638325

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#246

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638328

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#247

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638330

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#248

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638332

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#249

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:943
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638334

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#250

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81301-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:943
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638336

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81301-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81301-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#251

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:937
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638338

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#252

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638340

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#253

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638342

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#254

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:920
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:16 GMT
last-modified:Thu, 16 Oct 2025 23:41:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638344

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#255

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638346

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#256

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:936
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638348

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#257

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:923
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638350

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#258

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638352

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#259

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94186-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:939
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638354

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94186-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94186-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#260

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82309-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638356

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82309-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82309-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#261

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638358

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#262

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:936
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:41:17 GMT
last-modified:Thu, 16 Oct 2025 23:41:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638360

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#263

GET https://tx.fhir.org/r5/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4221
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638403

{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20250821042601.640Z. Server version 3.8.7 built 20250821042601.640Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.7.8"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-3.8.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-10-16T23:42:02.568Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "3.8.7","releaseDate" : "2025-08-21T04:26:01.640Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}

#264

GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:133329
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638404

{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r5/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2025-10-16T23:42:02.637Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "5.0.0"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/account-aggregate","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-balance-term","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-billing-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-function","version" : [{"code" : 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{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:cbcd48ac-3357-46b3-9faa-e86471b6679b","timestamp" : "2025-10-16T23:42:10.411Z","total" : 40,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "version","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "53075003","display" : "Distal phalanx of great toe"},{"system" : "http://snomed.info/sct","code" : "76986006","display" : "Distal phalanx of second toe"},{"system" : "http://snomed.info/sct","code" : "65258003","display" : "Distal phalanx of third toe"},{"system" : "http://snomed.info/sct","code" : "54333003","display" : "Distal phalanx of fourth toe"},{"system" : "http://snomed.info/sct","code" : "10770001","display" : "Distal phalanx of little toe"},{"system" : "http://snomed.info/sct","code" : "363670009","display" : "Interphalangeal joint structure of great toe"},{"system" : "http://snomed.info/sct","code" : "371216008","display" : "Distal interphalangeal joint structure of second toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371219001","display" : "Distal interphalangeal joint structure of third toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371205001","display" : "Distal interphalangeal joint structure of fourth toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371203008","display" : "Distal interphalangeal joint structure of fifth toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371292009","display" : "Proximal interphalangeal joint structure of second toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371255009","display" : "Proximal interphalangeal joint structure of third toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371288002","display" : "Proximal interphalangeal joint structure of fourth toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "371284000","display" : "Proximal interphalangeal joint structure of fifth toe (body structure)"},{"system" : "http://snomed.info/sct","code" : "67169006","display" : "Head of first metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "9677004","display" : "Head of second metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "46971007","display" : "Head of third metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "3134008","display" : "Head of fourth metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "71822005","display" : "Head of fifth metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "89221001","display" : "Base of first metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "90894004","display" : "Base of second metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "89995006","display" : "Base of third metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "15368009","display" : "Base of fourth metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "30980004","display" : "Base of fifth metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "38607000","display" : "Styloid process of fifth metatarsal bone"},{"system" : "http://snomed.info/sct","code" : "2979003","display" : "Medial cuneiform bone"},{"system" : "http://snomed.info/sct","code" : "19193007","display" : "Intermediate cuneiform bone"},{"system" : "http://snomed.info/sct","code" : "67411009","display" : "Lateral cuneiform bone"},{"system" : "http://snomed.info/sct","code" : "81012005","display" : "Cuboid"},{"system" : "http://snomed.info/sct","code" : "75772009","display" : "Navicular bone of foot"},{"system" : "http://snomed.info/sct","code" : "67453005","display" : "Talus"},{"system" : "http://snomed.info/sct","code" : "80144004","display" : "Calcaneus"},{"system" : "http://snomed.info/sct","code" : "6417001","display" : "Medial malleolus"},{"system" : "http://snomed.info/sct","code" : "113225006","display" : "Lateral malleolus of fibula"},{"system" : "http://snomed.info/sct","code" : "22457002","display" : "Head of fibula"},{"system" : "http://snomed.info/sct","code" : "45879002","display" : "Tibial tuberosity"},{"system" : "http://snomed.info/sct","code" : "122474001","display" : "Medial condyle of femur"},{"system" : "http://snomed.info/sct","code" : "122475000","display" : "Lateral condyle of femur"},{"system" : "http://snomed.info/sct","code" : "69030007","display" : "Ischial tuberosity"},{"system" : "http://snomed.info/sct","code" : "29850006","display" : "Iliac crest"}]}}

#266

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fhl7.org%2Ffhir%2FValueSet%2Fsecurity-label-data-examples&version=6.0.0-ballot3 HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:295
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638406

{"resourceType" : "Bundle","id" : "9ca6d190-d5b6-4c82-9210-57bc643605","meta" : {"lastUpdated" : "2025-10-16T23:42:11.005Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://hl7.org/fhir/ValueSet/security-label-data-examples&version=6.0.0-ballot3"}]}

#267

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fhl7.org%2Ffhir%2FValueSet%2Fsecurity-label-event-examples&version=6.0.0-ballot3 HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:296
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638407

{"resourceType" : "Bundle","id" : "85a7bd40-02b5-403e-9be0-ba66011e1c","meta" : {"lastUpdated" : "2025-10-16T23:42:11.083Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://hl7.org/fhir/ValueSet/security-label-event-examples&version=6.0.0-ballot3"}]}

#268

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122555007","display":"Venous blood specimen"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1122
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:12 GMT
last-modified:Thu, 16 Oct 2025 23:42:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638410

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122555007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Venous blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122555007","display" : "Venous blood specimen"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#122555007 (\"Venous blood specimen\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#122555007\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#269

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13303-3","display":"HLA-A+B+C (class I) [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:12 GMT
last-modified:Thu, 16 Oct 2025 23:42:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638412

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13303-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A+B+C (class I) [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13303-3","display" : "HLA-A+B+C (class I) [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#13303-3 (\"HLA-A+B+C (class I) [Type]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#13303-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#270

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:955
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:12 GMT
last-modified:Thu, 16 Oct 2025 23:42:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638414

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"Haplotype name\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#271

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:01:01G","display":"HLA-A*01:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1792
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:12 GMT
last-modified:Thu, 16 Oct 2025 23:42:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638416

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:01:01G (\"HLA-A*01:01:01G\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:01:01G\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#272

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1579
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:12 GMT
last-modified:Thu, 16 Oct 2025 23:42:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638418

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "code","valueCode" : "GTR000000000.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://www.ncbi.nlm.nih.gov/gtr\"\r\n"}]}

#273

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:964
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:12 GMT
last-modified:Thu, 16 Oct 2025 23:42:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638420

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"Gene studied [ID]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#274

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1513
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638422

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#275

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1572
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638425

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "code","valueCode" : "GTR000000000.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://www.ncbi.nlm.nih.gov/gtr\"\r\n"}]}

#276

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638427

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#277

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638429

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4931 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#278

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:02","display":"HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1776
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638431

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:02"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02 (\"HLA-A*01:02\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#279

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:983
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638433

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"Genotype display name\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#280

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1733
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638435

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#281

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1579
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638438

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "code","valueCode" : "GTR000000000.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://www.ncbi.nlm.nih.gov/gtr\"\r\n"}]}

#282

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HGG00041","display":"HLA-B*15:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1771
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638440

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HGG00041"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HGG00041 (\"HLA-B*15:01:01G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HGG00041\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#283

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932","display":"HLA-B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:13 GMT
last-modified:Thu, 16 Oct 2025 23:42:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638442

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4932"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4932 (\"HLA-B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4932\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#284

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932","display":"HLA-B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638444

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4932"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4932 (\"HLA-B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4932\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#285

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638446

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4932"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4932 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4932\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#286

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-B*57:01:01G","display":"HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1792
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638448

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-B*57:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G (\"HLA-B*57:01:01G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#287

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1747
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638450

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#288

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-C*01:02:01G","display":"HLA-C*01:02:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1785
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638452

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-C*01:02:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-C*01:02:01G (\"HLA-C*01:02:01G\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-C*01:02:01G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#289

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933","display":"HLA-C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638454

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4933"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4933 (\"HLA-C\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4933\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#290

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933","display":"HLA-C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1513
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638456

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4933"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4933 (\"HLA-C\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4933\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#291

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638458

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4933"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4933 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4933\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#292

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1754
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638460

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#293

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1690
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:14 GMT
last-modified:Thu, 16 Oct 2025 23:42:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638462

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23# (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#294

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1328
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:15 GMT
last-modified:Thu, 16 Oct 2025 23:42:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638464

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#295

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6","display":"Genetic variant assessment"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638473

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6","display" : "Genetic variant assessment"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"Genetic variant assessment\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#296

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:945
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638476

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA9633-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#297

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4","display":"Human reference sequence assembly version"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1036
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638478

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4","display" : "Human reference sequence assembly version"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"Human reference sequence assembly version\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#298

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:946
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638480

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA14029-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#299

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1009
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638482

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence ID\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#300

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638485

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#301

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic state"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:959
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638487

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic state"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"Allelic state\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#302

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:960
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638490

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6706-1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#303

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Ref nucleotide"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:971
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638492

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Ref nucleotide"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"Ref nucleotide\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#304

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Alt allele"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:956
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638496

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Alt allele"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"Alt allele\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#305

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6","display":"Genomic coord system"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:992
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638499

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6","display" : "Genomic coord system"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"Genomic coord system\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#306

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:932
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:16 GMT
last-modified:Thu, 16 Oct 2025 23:42:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638502

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30102-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#307

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA9633-4\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}

#308

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Check \"http://loinc.org#LA14029-5\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Filter \"LIST = LL1040-6\": Code \"LA14029-5\" found in http://loinc.org|2.81\r\n"}]}

#309

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Check \"http://loinc.org#LA6706-1\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Filter \"LIST = LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}

#310

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30102-0\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}

#311

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6705-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#312

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Check \"http://loinc.org#LA6705-3\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Filter \"LIST = LL381-5\": Code \"LA6705-3\" found in http://loinc.org|2.81\r\n"}]}

#313

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7","display":"Allelic phase"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:19 GMT
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x-request-id:238-2638521

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7","display" : "Allelic phase"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"Allelic phase\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#314

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}],"text":"Genetic analysis report"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:19 GMT
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pragma:no-cache
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}],"text" : "Genetic analysis report"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#315

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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date:Thu, 16 Oct 2025 23:42:21 GMT
last-modified:Thu, 16 Oct 2025 23:42:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638526

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA9633-4 ('Present')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA9633-4 ('Present')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA9633-4\"\r\n"}]}

#316

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638528

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#317

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9","display":"Discrete genetic variant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:988
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
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server:nginx
x-request-id:238-2638530

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9","display" : "Discrete genetic variant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"Discrete genetic variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#318

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"30880","display":"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1608
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
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x-request-id:238-2638532

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "30880"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#30880 (\"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#30880\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#319

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497","display":"ACAD9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1516
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
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x-request-id:238-2638534

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:21497"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:21497 (\"ACAD9\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:21497\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#320

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
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server:nginx
x-request-id:238-2638536

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#321

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
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x-request-id:238-2638538

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#322

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:895
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638540

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#323

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1626
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638542

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#324

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638544

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#325

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:879
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:24 GMT
last-modified:Thu, 16 Oct 2025 23:42:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638546

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#326

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:960
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638548

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6690-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Substitution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6690-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#327

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:948
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638550

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6683-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#328

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:960
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638552

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6706-1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#329

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497","display":"ACAD9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638555

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:21497"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:21497 (\"ACAD9\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:21497\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#330

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638557

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:21497"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:21497 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:21497\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#331

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1418
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638559

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000003.11:g.128625063C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#332

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638561

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_014049.4:c.1249C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#333

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1398
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638563

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_054768.2:p.Arg417Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#334

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-ballot","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:25 GMT
last-modified:Thu, 16 Oct 2025 23:42:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638566

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA6690-7 ('Substitution')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6690-7 ('Substitution')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Check \"http://loinc.org#LA6690-7\"\r\n"}]}

#335

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1110
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638568

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Check \"http://loinc.org#LA6683-2\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Filter \"LIST = LL378-1\": Code \"LA6683-2\" found in http://loinc.org|2.81\r\n"}]}

#336

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1133
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638570

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Parameters: disp-lang=en-US, default-to-latest\r\n15 15: 15ms http://loinc.org/vs/LL381-5: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 15ms http://loinc.org/vs/LL381-5: Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n15 0: 15ms http://loinc.org/vs/LL381-5: Check \"http://loinc.org#LA6706-1\"\r\n15 0: 15ms http://loinc.org/vs/LL381-5: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 15ms http://loinc.org/vs/LL381-5: Filter \"LIST = LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}

#337

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6668-3","display":"Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638572

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6668-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6668-3","display" : "Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6668-3 (\"Pathogenic\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6668-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#338

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0012624","display":"acyl-CoA dehydrogenase 9 deficiency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1660
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638574

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "code","valueCode" : "MONDO:0012624"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://purl.obolibrary.org/obo/mondo.owl#MONDO:0012624 (\"acyl-CoA dehydrogenase 9 deficiency\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://purl.obolibrary.org/obo/mondo.owl#MONDO:0012624\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://purl.obolibrary.org/obo/mondo.owl\"\r\n"}]}

#339

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"31934","display":"NM_000106.5(CYP2D6):c.886C>T (p.Arg296Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1615
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638576

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "31934"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#31934 (\"NM_000106.5(CYP2D6):c.886C>T (p.Arg296Cys)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#31934\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#340

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638578

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#341

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638580

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#342

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:886
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638582

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#343

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1375
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:26 GMT
last-modified:Thu, 16 Oct 2025 23:42:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638584

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000106.5:c.886C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#344

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1390
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638586

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000097.3:p.Arg296Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#345

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1616
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638588

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "38486"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#38486 (\"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#38486\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#346

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638590

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#347

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1380
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638592

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000106.5:c.1457G>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#348

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"293498008","display":"Debrisoquine adverse reaction (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1168
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638594

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "293498008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Debrisoquine adverse reaction"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "293498008","display" : "Debrisoquine adverse reaction (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#293498008 (\"Debrisoquine adverse reaction (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#293498008\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#349

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1184
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638596

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Check \"http://loinc.org#LA26423-6\"\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Filter \"LIST = LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}

#350

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2342
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638598

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26423-6\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}

#351

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C43359","display":"Group"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:913
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638600

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C43359"},{"name" : "display","valueString" : "Group"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43359 (\"Group\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43359\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.31.0)\" (content = fragment)\r\n"}]}

#352

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1550
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638602

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#353

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1522
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:27 GMT
last-modified:Thu, 16 Oct 2025 23:42:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638604

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9*2*5\""},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9*2*5\" (\"CYP2C9 *2/*5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9*2*5\"\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#354

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623","display":"CYP2C9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638606

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2623 (\"CYP2C9\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2623\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#355

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663","display":"VKORC1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1510
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638608

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:23663"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:23663 (\"VKORC1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:23663\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#356

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623","display":"CYP2C9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638611

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2623 (\"CYP2C9\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2623\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#357

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638613

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:2623 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:2623\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#358

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663","display":"VKORC1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1517
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638615

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:23663"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:23663 (\"VKORC1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:23663\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#359

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2551
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638617

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:23663"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:23663 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:23663\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#360

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"Warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1067
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638619

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "Warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"Warfarin\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#361

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:972
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:28 GMT
last-modified:Thu, 16 Oct 2025 23:42:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638621

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA25390-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#362

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9*2*5\""},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9*2*5\" (\"CYP2C9 *2/*5\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9*2*5\"\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#363

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA25390-8\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA25390-8\" found in http://loinc.org|2.81\r\n"}]}

#364

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#365

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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#366

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#367

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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#368

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Analysing\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: CodeSystem found: \"urn:ietf:bcp:13|\"\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Validate \"[#text/plain (\"\")]\" and infer system\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Check \"#text/plain\"\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}

#369

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"mimetypes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/mimetypes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1024"}],"version":"6.0.0-ballot3","name":"MimeTypes","title":"Mime Types","status":"active","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International - FHIR-Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all possible codes from BCP-13 (see http://tools.ietf.org/html/bcp13)","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:29 GMT
last-modified:Thu, 16 Oct 2025 23:42:29 GMT
pragma:no-cache
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x-request-id:238-2638641

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: CodeSystem found: \"urn:ietf:bcp:13|\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Validate \"[#text/plain (\"\")]\" and infer system\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Check \"#text/plain\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}

#370

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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last-modified:Thu, 16 Oct 2025 23:42:29 GMT
pragma:no-cache
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x-request-id:238-2638643

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9*2*5\""},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9*2*5\" (\"CYP2C9 *2/*5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9*2*5\"\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#371

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:29 GMT
last-modified:Thu, 16 Oct 2025 23:42:29 GMT
pragma:no-cache
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x-request-id:238-2638645

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA19542-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#372

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:29 GMT
last-modified:Thu, 16 Oct 2025 23:42:29 GMT
pragma:no-cache
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x-request-id:238-2638648

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA19542-2\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA19542-2\" found in http://loinc.org|2.81\r\n"}]}

#373

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":4}],"url":"http://hl7.org/fhir/ValueSet/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1396"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://hl7.org/fhir/CodeSystem/task-code","version":"6.0.0-ballot3"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablecodesystem"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/CodeSystem/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.4.1397"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"HL7 International","description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"valueSet":"http://hl7.org/fhir/ValueSet/task-code.html","content":"complete","concept":[{"code":"approve","display":"Activate/approve the focal resource","definition":"Take what actions are needed to transition the focus resource from 'draft' to 'active' or 'in-progress', as appropriate for the resource type.  This may involve additing additional content, approval, validation, etc."},{"code":"fulfill","display":"Fulfill the focal request","definition":"Act to perform the actions described in the focus request.  This might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events.  The degree of fulfillment requested might be limited by Task.restriction."},{"code":"instantiate","display":"Instantiate the focal definition","definition":"Act to perform the actions defined in the focus definition resource (ActivityDefinition, PlanDefinition, Questionnaire, etc.)  For PlanDefinition or ActivityDefinition, this might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events.  For Questionnaire, this would result in a QuestionnaireResponse - and possibly resources constructed using data extracted from the response.  The degree of fulfillment requested might be limited by Task.restriction."},{"code":"abort","display":"Mark the focal resource as no longer active","definition":"Abort, cancel or withdraw the focal resource, as appropriate for the type of resource."},{"code":"replace","display":"Replace the focal resource with the input resource","definition":"Replace the focal resource with the specified input resource"},{"code":"change","display":"Change the focal resource","definition":"Update the focal resource of the owning system to reflect the content specified as the Task.focus"},{"code":"suspend","display":"Suspend the focal resource","definition":"Transition the focal resource from 'active' or 'in-progress' to 'suspended'"},{"code":"resume","display":"Re-activate the focal resource","definition":"Transition the focal resource from 'suspended' to 'active' or 'in-progress' as appropriate for the resource type."}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:29 GMT
last-modified:Thu, 16 Oct 2025 23:42:29 GMT
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server:nginx
x-request-id:238-2638651

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Analysing\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: CodeSystem not found: \"http://hl7.org/fhir/CodeSystem/task-code|6.0.0-ballot3\"\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Check \"http://loinc.org#LA26423-6\"\r\n"}]}

#374

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1258
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638653

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#375

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638656

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "version","valueString" : "137"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP|137\"\r\n"}]}

#376

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81299-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638658

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81299-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81299-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#377

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81300-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638660

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81300-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81300-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#378

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","version":"???","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1791
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638663

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "38486"},{"name" : "version","valueString" : "???"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar|???#38486 (\"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar|???#38486\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar|???\"\r\n"}]}

#379

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1522
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638665

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9 *2/*5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 *2/*5 (\"CYP2C9 *2/*5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9 *2/*5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#380

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1522
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:30 GMT
last-modified:Thu, 16 Oct 2025 23:42:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638667

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9 *2/*5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 *2/*5 (\"CYP2C9 *2/*5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9 *2/*5\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#381

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1522
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638669

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9 *2/*5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 *2/*5 (\"CYP2C9 *2/*5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9 *2/*5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#382

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript ref sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1006
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638671

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript ref sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"Transcript ref sequence ID\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#383

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_022787.3","display":"NM_022787.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638673

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_022787.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_022787.3 (\"NM_022787.3\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_022787.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#384

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:982
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638675

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"Genomic ref allele [ID]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#385

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638677

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"Genomic alt allele [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#386

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"RCV000664188.1","display":"NM_022787.3(NMNAT1):c.[53A>G];[769G>A] AND Cone-rod dystrophy"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1654
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638679

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "RCV000664188.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#RCV000664188.1 (\"NM_022787.3(NMNAT1):c.[53A>G];[769G>A] AND Cone-rod dystrophy\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#RCV000664188.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#387

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6","display":"DNA change (c.HGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:970
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638681

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6","display" : "DNA change (c.HGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"DNA change (c.HGVS)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#388

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A","display":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:31 GMT
last-modified:Thu, 16 Oct 2025 23:42:31 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638683

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"NM_022787.3:c.769G>A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#389

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1375
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638685

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_022787.3:c.769G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#390

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G","display":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638687

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"NM_022787.3:c.53A>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#391

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1378
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638690

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_022787.3:c.53A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#392

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94076-7","display":"Mutations/Megabase [# Ratio] in Tumor"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1031
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638692

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94076-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Mutations/Megabase [# Ratio] in Tumor"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94076-7","display" : "Mutations/Megabase [# Ratio] in Tumor"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94076-7 (\"Mutations/Megabase [# Ratio] in Tumor\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94076-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#393

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:951
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638694

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26398-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#394

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9","display":"Genomic DNA change (gHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638696

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9","display" : "Genomic DNA change (gHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"Genomic DNA change (gHGVS)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#395

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T","display":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:922
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:32 GMT
last-modified:Thu, 16 Oct 2025 23:42:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638698

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"NC_000007.13:g.140453136A>T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#396

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"13961","display":"Clinvar ID 13961"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1589
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638700

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "13961"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#13961 (\"Clinvar ID 13961\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#13961\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#397

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3","display":"Amino acid change (pHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:995
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638702

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3","display" : "Amino acid change (pHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"Amino acid change (pHGVS)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#398

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu","display":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:909
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638704

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"NP_004324.2:p.Val600Glu\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#399

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:960
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638707

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"Gene studied ID\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#400

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097","display":"BRAF"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1505
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638709

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1097"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1097 (\"BRAF\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1097\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#401

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1129
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638711

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Check \"http://loinc.org#LA26398-0\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Filter \"LIST = LL4048-6\": Code \"LA26398-0\" found in http://loinc.org|2.81\r\n"}]}

#402

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1418
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638714

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000007.13:g.140453136A>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#403

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1390
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638716

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_004324.2:p.Val600Glu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#404

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097","display":"BRAF"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1505
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638718

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1097"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1097 (\"BRAF\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1097\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#405

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:33 GMT
last-modified:Thu, 16 Oct 2025 23:42:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638720

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1097"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:1097 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:1097\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#406

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:987
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638722

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26811-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#407

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8","display":"Genetic variation clinical significance [Imp]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1055
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638724

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8","display" : "Genetic variation clinical significance [Imp]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"Genetic variation clinical significance [Imp]\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#408

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of Evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:971
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638726

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of Evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"Level of Evidence\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#409

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30200-2","display":"Very strong evidence pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1014
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638728

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30200-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Very strong evidence pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30200-2","display" : "Very strong evidence pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30200-2 (\"Very strong evidence pathogenic\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30200-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#410

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2284
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638730

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'; The provided code 'http://loinc.org#LA26398-0 ('Sequencing')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26398-0 ('Sequencing')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26398-0\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26398-0\" not found in http://loinc.org|2.81\r\n"}]}

#411

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1165
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638732

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Check \"http://loinc.org#LA26811-2\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Filter \"LIST = LL4048-6\": Code \"LA26811-2\" found in http://loinc.org|2.81\r\n"}]}

#412

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2323
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638735

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'; The provided code 'http://loinc.org#LA26811-2 ('Computational analysis')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26811-2 ('Computational analysis')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26811-2\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26811-2\" not found in http://loinc.org|2.81\r\n"}]}

#413

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1043
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638737

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://hl7.org/fhir/sid/icd-10-cm","code" : "C16.0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.31.0)\" (content = complete)\r\n"}]}

#414

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:987
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:34 GMT
last-modified:Thu, 16 Oct 2025 23:42:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638739

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"Genomic source class\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#415

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:945
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638741

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6684-0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#416

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975","display":"PIK3CA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638744

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8975"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8975 (\"PIK3CA\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8975\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#417

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G","display":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:899
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638746

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"NM_006218.4:c.3140A>G\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#418

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA change type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:958
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638748

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA change type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"DNA change type\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#419

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1565
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638750

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"substitution\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#420

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg","display":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:914
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638752

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"NP_006209.2:p.His1047Arg\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#421

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1022
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638754

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"Transcript reference sequence [ID]\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#422

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006218.3","display":"NM_006218.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638756

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006218.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3 (\"NM_006218.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#423

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6","display":"Sample VAF"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:978
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:35 GMT
last-modified:Thu, 16 Oct 2025 23:42:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638758

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6","display" : "Sample VAF"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"Sample VAF\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#424

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5","display":"Allelic read depth"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:974
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638760

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5","display" : "Allelic read depth"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"Allelic read depth\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#425

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1107
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638762

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Check \"http://loinc.org#LA6684-0\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Filter \"LIST = LL378-1\": Code \"LA6684-0\" found in http://loinc.org|2.81\r\n"}]}

#426

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975","display":"PIK3CA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638764

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8975"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8975 (\"PIK3CA\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8975\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#427

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638766

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8975"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:8975 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:8975\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#428

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638769

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006218.4:c.3140A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#429

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1572
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638771

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"substitution\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#430

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2709
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638773

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#431

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1395
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638776

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_006209.2:p.His1047Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#432

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989","display":"NRAS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1505
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638778

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7989"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7989 (\"NRAS\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7989\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#433

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T","display":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:882
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:36 GMT
last-modified:Thu, 16 Oct 2025 23:42:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638780

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"NM_002524.4:c.34G>T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#434

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_002524.4","display":"NM_002524.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638783

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_002524.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_002524.4 (\"NM_002524.4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_002524.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#435

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989","display":"NRAS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638785

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7989"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7989 (\"NRAS\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7989\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#436

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638787

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7989"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7989 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7989\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#437

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1370
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638789

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_002524.4:c.34G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#438

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712","display":"FBXW7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638791

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:16712"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:16712 (\"FBXW7\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:16712\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#439

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A","display":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:914
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638793

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"NM_001349798.2:c.1394G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#440

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His","display":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:924
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:37 GMT
last-modified:Thu, 16 Oct 2025 23:42:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638795

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"NP_001336727.1:p.Arg465His\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#441

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001349798.2","display":"NM_001349798.2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1607
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638797

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001349798.2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001349798.2 (\"NM_001349798.2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001349798.2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#442

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712","display":"FBXW7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638800

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:16712"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:16712 (\"FBXW7\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:16712\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#443

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638802

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:16712"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:16712 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:16712\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#444

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1403
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638804

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001349798.2:c.1394G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#445

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1413
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638806

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_001336727.1:p.Arg465His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#446

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133","display":"KMT2D"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1513
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638808

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7133"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7133 (\"KMT2D\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7133\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#447

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA","display":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:934
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638810

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"NM_003482.3:c.7900_7901delCA\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#448

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159","display":"deletion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1568
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:38 GMT
last-modified:Thu, 16 Oct 2025 23:42:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638812

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000159 (\"deletion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000159\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#449

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003482.3","display":"NM_003482.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638814

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_003482.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_003482.3 (\"NM_003482.3\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_003482.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#450

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133","display":"KMT2D"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1513
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638816

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7133"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7133 (\"KMT2D\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7133\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#451

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638818

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7133"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7133 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7133\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#452

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1415
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638820

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_003482.3:c.7900_7901delCA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#453

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159","display":"deletion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1561
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638822

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000159 (\"deletion\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000159\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#454

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2709
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638824

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0000159 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0000159\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#455

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T","display":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:894
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638826

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"NM_006218.3:c.333G>T\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#456

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006218.3","display":"NM_006218.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638828

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006218.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3 (\"NM_006218.3\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#457

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1383
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:39 GMT
last-modified:Thu, 16 Oct 2025 23:42:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638830

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006218.3:c.333G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#458

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126","display":"IRS2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638832

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:6126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:6126 (\"IRS2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:6126\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#459

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T","display":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638834

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"NM_003749.2:c.3960C>T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#460

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003749.2","display":"NM_003749.2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638836

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_003749.2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_003749.2 (\"NM_003749.2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_003749.2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#461

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126","display":"IRS2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638838

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:6126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:6126 (\"IRS2\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:6126\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#462

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638840

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:6126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:6126 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:6126\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#463

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638842

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n94 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_003749.2:c.3960C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#464

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787","display":"CDKN2A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638844

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1787"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1787 (\"CDKN2A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1787\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#465

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:40 GMT
last-modified:Thu, 16 Oct 2025 23:42:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638846

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#466

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638848

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#467

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000077.4","display":"NM_000077.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638850

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000077.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000077.4 (\"NM_000077.4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000077.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#468

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787","display":"CDKN2A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638852

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1787"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1787 (\"CDKN2A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1787\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#469

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2553
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638854

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1787"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n15 15: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:1787 (\"\")]\"\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:1787\"\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#470

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638856

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000077.4:c.9_32del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#471

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1418
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638858

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000068.1:p.Ala4_Pro11del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#472

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949","display":"RECQL4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:41 GMT
last-modified:Thu, 16 Oct 2025 23:42:41 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638860

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:9949"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:9949 (\"RECQL4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:9949\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#473

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638862

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#474

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:886
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638864

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#475

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004260.4","display":"NM_004260.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638866

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_004260.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_004260.4 (\"NM_004260.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_004260.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#476

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949","display":"RECQL4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1516
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638868

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:9949"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:9949 (\"RECQL4\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:9949\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#477

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638870

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:9949"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:9949 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:9949\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#478

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1380
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638872

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_004260.4:c.2086C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#479

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1390
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:42 GMT
last-modified:Thu, 16 Oct 2025 23:42:42 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638874

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 79: 79ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_004251.4:p.Arg696Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#480

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483","display":"RYR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638876

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10483 (\"RYR1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10483\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#481

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638878

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#482

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:883
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638880

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#483

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000540.2","display":"NM_000540.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638882

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000540.2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000540.2 (\"NM_000540.3\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000540.2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#484

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483","display":"RYR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1508
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638884

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10483 (\"RYR1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10483\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#485

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2551
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638886

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:10483 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:10483\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#486

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1380
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:43 GMT
last-modified:Thu, 16 Oct 2025 23:42:43 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638888

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000540.3:c.4964G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#487

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1403
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638890

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000531.2:p.Arg1655Leu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#488

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519","display":"SACS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638892

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10519"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10519 (\"SACS\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10519\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#489

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:882
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638894

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#490

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014363.5","display":"NM_014363.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638896

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014363.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014363.5 (\"NM_014363.5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014363.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#491

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519","display":"SACS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638898

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10519"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10519 (\"SACS\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10519\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#492

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638900

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10519"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:10519 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:10519\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#493

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1385
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638902

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 79: 79ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_014363.5:c.12118G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#494

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086","display":"SLIT2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:44 GMT
last-modified:Thu, 16 Oct 2025 23:42:44 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638904

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11086"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11086 (\"SLIT2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11086\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#495

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638906

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#496

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004787.3","display":"NM_004787.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638908

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_004787.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_004787.3 (\"NM_004787.3\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_004787.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#497

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086","display":"SLIT2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638910

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11086"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11086 (\"SLIT2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11086\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#498

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638912

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11086"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11086 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11086\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#499

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638914

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_004787.3:c.1290C>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#500

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100","display":"SMARCA4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1511
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638916

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11100"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11100 (\"SMARCA4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11100\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#501

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638918

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#502

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:886
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638920

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#503

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003072.5","display":"NM_003072.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:45 GMT
last-modified:Thu, 16 Oct 2025 23:42:45 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638922

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_003072.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_003072.5 (\"NM_003072.5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_003072.5\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#504

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100","display":"SMARCA4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1518
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:46 GMT
last-modified:Thu, 16 Oct 2025 23:42:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638924

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11100"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11100 (\"SMARCA4\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11100\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#505

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:46 GMT
last-modified:Thu, 16 Oct 2025 23:42:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638926

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11100"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11100 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11100\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#506

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:46 GMT
last-modified:Thu, 16 Oct 2025 23:42:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638928

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_003072.5:c.2372C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#507

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1390
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:46 GMT
last-modified:Thu, 16 Oct 2025 23:42:46 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638930

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_003063.2:p.Ala791Val\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#508

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81695-9","display":"Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1135
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:47 GMT
last-modified:Thu, 16 Oct 2025 23:42:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638932

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81695-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81695-9","display" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81695-9 (\"Microsatellite instability [Interpretation] in Cancer specimen Qualitative\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81695-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#509

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:946
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:47 GMT
last-modified:Thu, 16 Oct 2025 23:42:47 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638935

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14122-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Stable"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA14122-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#510

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T","display":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:919
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638937

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"NC_000009.12:g.5073770G>T\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#511

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe","display":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:909
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638939

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"NP_004963.1:p.Val617Phe\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#512

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2","display":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1490
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638941

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "JAK2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#JAK2 (\"JAK2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#JAK2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#513

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1400
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638943

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000009.12:g.5073770G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#514

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1390
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638945

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_004963.1:p.Val617Phe\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#515

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2","display":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1497
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638947

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "JAK2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#JAK2 (\"JAK2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#JAK2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#516

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2525
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638949

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "JAK2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#JAK2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#JAK2\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#517

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A","display":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:48 GMT
last-modified:Thu, 16 Oct 2025 23:42:48 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638951

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"NC_000004.11:g.55972974T>A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#518

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His","display":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:909
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638953

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"NP_002244.1:p.Gln472His\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#519

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR","display":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1493
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638955

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "KDR"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#KDR (\"KDR\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#KDR\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#520

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1413
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638957

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000004.11:g.55972974T>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#521

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1398
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638959

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_002244.1:p.Gln472His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#522

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR","display":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1486
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638961

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "KDR"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#KDR (\"KDR\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#KDR\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#523

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2522
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638963

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "KDR"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#KDR (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#KDR\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#524

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del","display":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:972
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:49 GMT
last-modified:Thu, 16 Oct 2025 23:42:49 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638965

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"NC_000002.12:g.211713666_211713668del\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#525

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4","display":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1501
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638967

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "ERBB4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#ERBB4 (\"ERBB4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#ERBB4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#526

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1468
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638969

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000002.12:g.211713666_211713668del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#527

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4","display":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1501
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638971

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "ERBB4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#ERBB4 (\"ERBB4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#ERBB4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#528

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2528
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638973

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "ERBB4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#ERBB4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#ERBB4\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#529

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"1193326","display":"Ruxolitinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1084
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638975

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "1193326"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "ruxolitinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "1193326","display" : "Ruxolitinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#1193326 (\"Ruxolitinib\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#1193326\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#530

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:954
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638977

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6677-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#531

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1820
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638980

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6677-4\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#532

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7","display":"Medication assessed"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:975
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:50 GMT
last-modified:Thu, 16 Oct 2025 23:42:50 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638982

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7","display" : "Medication assessed"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"Medication assessed\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#533

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2259
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:51 GMT
last-modified:Thu, 16 Oct 2025 23:42:51 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638984

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#534

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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date:Thu, 16 Oct 2025 23:42:51 GMT
last-modified:Thu, 16 Oct 2025 23:42:51 GMT
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x-request-id:238-2638987

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA14122-8\"\r\n"}]}

#535

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:52 GMT
last-modified:Thu, 16 Oct 2025 23:42:52 GMT
pragma:no-cache
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x-request-id:238-2638989

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Check \"http://loinc.org#LA26423-6\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Filter \"LIST = LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}

#536

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"103","display":"mercaptopurine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:52 GMT
last-modified:Thu, 16 Oct 2025 23:42:52 GMT
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x-request-id:238-2638991

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "103"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "mercaptopurine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "103","display" : "mercaptopurine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#103 (\"mercaptopurine\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#103\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#537

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:52 GMT
last-modified:Thu, 16 Oct 2025 23:42:52 GMT
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x-request-id:238-2638993

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26423-6\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}

#538

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:52 GMT
last-modified:Thu, 16 Oct 2025 23:42:52 GMT
pragma:no-cache
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x-request-id:238-2638995

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"genotype display name\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#539

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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last-modified:Thu, 16 Oct 2025 23:42:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638997

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4/*35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#540

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype Name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:955
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:52 GMT
last-modified:Thu, 16 Oct 2025 23:42:52 GMT
pragma:no-cache
server:nginx
x-request-id:238-2638999

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype Name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"Haplotype Name\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#541

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1496
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639001

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#542

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1607
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639003

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#543

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1494
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639005

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#544

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639007

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#545

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1613
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639009

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#546

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1503
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639011

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *35B\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#547

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1501
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639013

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#548

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1499
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:53 GMT
last-modified:Thu, 16 Oct 2025 23:42:53 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639015

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4/*35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#549

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1499
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:54 GMT
last-modified:Thu, 16 Oct 2025 23:42:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639017

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4/*35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#550

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1503
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:54 GMT
last-modified:Thu, 16 Oct 2025 23:42:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639019

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *35B\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#551

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1494
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:54 GMT
last-modified:Thu, 16 Oct 2025 23:42:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639021

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#552

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":4}],"url":"http://hl7.org/fhir/ValueSet/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1396"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://hl7.org/fhir/CodeSystem/task-code","version":"6.0.0-ballot3"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablecodesystem"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/CodeSystem/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.4.1397"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"HL7 International","description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"valueSet":"http://hl7.org/fhir/ValueSet/task-code.html","content":"complete","concept":[{"code":"approve","display":"Activate/approve the focal resource","definition":"Take what actions are needed to transition the focus resource from 'draft' to 'active' or 'in-progress', as appropriate for the resource type.  This may involve additing additional content, approval, validation, etc."},{"code":"fulfill","display":"Fulfill the focal request","definition":"Act to perform the actions described in the focus request.  This might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events.  The degree of fulfillment requested might be limited by Task.restriction."},{"code":"instantiate","display":"Instantiate the focal definition","definition":"Act to perform the actions defined in the focus definition resource (ActivityDefinition, PlanDefinition, Questionnaire, etc.)  For PlanDefinition or ActivityDefinition, this might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events.  For Questionnaire, this would result in a QuestionnaireResponse - and possibly resources constructed using data extracted from the response.  The degree of fulfillment requested might be limited by Task.restriction."},{"code":"abort","display":"Mark the focal resource as no longer active","definition":"Abort, cancel or withdraw the focal resource, as appropriate for the type of resource."},{"code":"replace","display":"Replace the focal resource with the input resource","definition":"Replace the focal resource with the specified input resource"},{"code":"change","display":"Change the focal resource","definition":"Update the focal resource of the owning system to reflect the content specified as the Task.focus"},{"code":"suspend","display":"Suspend the focal resource","definition":"Transition the focal resource from 'active' or 'in-progress' to 'suspended'"},{"code":"resume","display":"Re-activate the focal resource","definition":"Transition the focal resource from 'suspended' to 'active' or 'in-progress' as appropriate for the resource type."}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2387
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:54 GMT
last-modified:Thu, 16 Oct 2025 23:42:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639024

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: CodeSystem not found: \"http://hl7.org/fhir/CodeSystem/task-code|6.0.0-ballot3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Check \"http://loinc.org#LA26423-6\"\r\n"}]}

#553

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"706687001","display":"Software (physical object)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1119
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:54 GMT
last-modified:Thu, 16 Oct 2025 23:42:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639026

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "706687001"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Software"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "706687001","display" : "Software (physical object)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#706687001 (\"Software (physical object)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#706687001\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#554

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:54 GMT
last-modified:Thu, 16 Oct 2025 23:42:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639029

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "14909"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#14909 (\"HLA-B*15:02\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#14909\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#555

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:55 GMT
last-modified:Thu, 16 Oct 2025 23:42:55 GMT
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x-request-id:238-2639031

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "14909"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#14909 (\"HLA-B*15:02\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#14909\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#556

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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last-modified:Thu, 16 Oct 2025 23:42:55 GMT
pragma:no-cache
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA19541-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#557

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2002","display":"Carbamazepine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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last-modified:Thu, 16 Oct 2025 23:42:55 GMT
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x-request-id:238-2639035

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2002"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "carbamazepine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2002","display" : "Carbamazepine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2002 (\"Carbamazepine\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2002\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#558

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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last-modified:Thu, 16 Oct 2025 23:42:55 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA19541-4\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA19541-4\" found in http://loinc.org|2.81\r\n"}]}

#559

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:55 GMT
last-modified:Thu, 16 Oct 2025 23:42:55 GMT
pragma:no-cache
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x-request-id:238-2639040

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "14909"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#14909 (\"HLA-B*15:02\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#14909\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#560

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://loinc.org","code":"57979-7","display":"HLA-B*15:02 [Presence]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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last-modified:Thu, 16 Oct 2025 23:42:55 GMT
pragma:no-cache
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57979-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-B*15:02 [Presence]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://loinc.org","code" : "57979-7","display" : "HLA-B*15:02 [Presence]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\"), http://loinc.org#57979-7 (\"HLA-B*15:02 [Presence]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#57979-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"57979-7\" found in http://loinc.org|2.81\r\n"}]}

#561

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
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connection:keep-alive
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date:Thu, 16 Oct 2025 23:42:55 GMT
last-modified:Thu, 16 Oct 2025 23:42:55 GMT
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x-request-id:238-2639045

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated; The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://example.org/hgsc.bcm.edu/lab-test-codes/","code" : "emerge-seq-ngs-pnl"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[1].code"],"expression" : ["CodeableConcept.coding[1].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["CodeableConcept.coding[1].system"],"expression" : ["CodeableConcept.coding[1].system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\"), http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n"}]}

#562

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
content-length:1581
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:55 GMT
last-modified:Thu, 16 Oct 2025 23:42:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639047

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "638797"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#638797 (\"CYP2C19*2/*2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#638797\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#563

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:55 GMT
last-modified:Thu, 16 Oct 2025 23:42:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639049

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "638797"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#638797 (\"CYP2C19*2/*2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#638797\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#564

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639051

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2621"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2621 (\"CYP2C19\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2621\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#565

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639053

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2621"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:2621 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:2621\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#566

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639055

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2621"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2621 (\"CYP2C19\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2621\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#567

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10","display":"b37 Chr10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1589
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639057

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"b37 Chr10\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#568

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1006
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639059

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30102-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#569

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1505
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639061

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:262 (\"CYP2C19\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:262\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#570

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2537
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639063

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:262 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:262\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#571

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639065

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:262 (\"CYP2C19\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:262\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#572

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639067

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002073 (\"wild type\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002073\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#573

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1186
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639069

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30102-0\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}

#574

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:56 GMT
last-modified:Thu, 16 Oct 2025 23:42:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639071

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002073 (\"wild type\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002073\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#575

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2701
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:57 GMT
last-modified:Thu, 16 Oct 2025 23:42:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639073

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0002073 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0002073\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#576

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:57 GMT
last-modified:Thu, 16 Oct 2025 23:42:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639075

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#577

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1405
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:57 GMT
last-modified:Thu, 16 Oct 2025 23:42:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639077

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000010.10:g.96540410G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#578

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1562
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:57 GMT
last-modified:Thu, 16 Oct 2025 23:42:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639079

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"wild type\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#579

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:57 GMT
last-modified:Thu, 16 Oct 2025 23:42:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639081

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"wild type\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#580

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2701
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:57 GMT
last-modified:Thu, 16 Oct 2025 23:42:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639083

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#581

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"32968","display":"clopidogrel"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1069
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:58 GMT
last-modified:Thu, 16 Oct 2025 23:42:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639085

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "32968"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "clopidogrel"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "32968","display" : "clopidogrel"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#32968 (\"clopidogrel\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#32968\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#582

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:965
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:58 GMT
last-modified:Thu, 16 Oct 2025 23:42:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639087

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA9657-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#583

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:58 GMT
last-modified:Thu, 16 Oct 2025 23:42:58 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA9657-3\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA9657-3\" found in http://loinc.org|2.81\r\n"}]}

#584

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"121243","display":"voriconazole"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:58 GMT
last-modified:Thu, 16 Oct 2025 23:42:58 GMT
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x-request-id:238-2639092

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "121243"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "voriconazole"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "121243","display" : "voriconazole"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#121243 (\"voriconazole\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#121243\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#585

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2556","display":"citalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:58 GMT
last-modified:Thu, 16 Oct 2025 23:42:58 GMT
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x-request-id:238-2639094

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2556"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "citalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2556","display" : "citalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2556 (\"citalopram\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2556\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#586

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"321988","display":"escitalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:58 GMT
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x-request-id:238-2639096

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "321988"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "escitalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "321988","display" : "escitalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#321988 (\"escitalopram\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#321988\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#587

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"704","display":"amitriptyline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:58 GMT
last-modified:Thu, 16 Oct 2025 23:42:58 GMT
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x-request-id:238-2639098

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "704"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "amitriptyline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "704","display" : "amitriptyline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#704 (\"amitriptyline\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#704\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#588

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:59 GMT
last-modified:Thu, 16 Oct 2025 23:42:59 GMT
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x-request-id:238-2639100

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#589

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1408
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:59 GMT
last-modified:Thu, 16 Oct 2025 23:42:59 GMT
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x-request-id:238-2639102

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000016.9:g.31096368G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#590

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1067
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:42:59 GMT
last-modified:Thu, 16 Oct 2025 23:42:59 GMT
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x-request-id:238-2639106

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"warfarin\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#591

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:42:59 GMT
last-modified:Thu, 16 Oct 2025 23:42:59 GMT
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x-request-id:238-2639108

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA25391-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#592

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:42:59 GMT
last-modified:Thu, 16 Oct 2025 23:42:59 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA25391-6\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA25391-6\" found in http://loinc.org|2.81\r\n"}]}

#593

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:43:00 GMT
last-modified:Thu, 16 Oct 2025 23:43:00 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "638797"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#638797 (\"CYP2C19*2/*2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#638797\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#594

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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date:Thu, 16 Oct 2025 23:43:00 GMT
last-modified:Thu, 16 Oct 2025 23:43:00 GMT
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x-request-id:238-2639115

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"Haplotype name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#57290-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#595

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:43:00 GMT
last-modified:Thu, 16 Oct 2025 23:43:00 GMT
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x-request-id:238-2639118

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}

#596

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#597

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
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server:nginx
x-request-id:238-2639122

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4931 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4931\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#598

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639124

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#599

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1349
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639126

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"Genotype display name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#57290-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#600

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639128

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#601

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639130

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#602

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639132

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#603

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639134

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#604

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881","display":"NOTCH1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:01 GMT
last-modified:Thu, 16 Oct 2025 23:43:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639136

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7881"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7881 (\"NOTCH1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7881\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#605

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:964
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639138

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21262-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#606

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639140

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000009.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#607

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639142

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#608

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1383
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639144

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_060087.3:p.A1931T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#609

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1380
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639146

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_017617.5:c.5791G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#610

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881","display":"NOTCH1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639148

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7881"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7881 (\"NOTCH1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7881\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#611

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639150

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7881"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7881 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7881\"\r\n16 16: 16ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#612

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1144
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:02 GMT
last-modified:Thu, 16 Oct 2025 23:43:02 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639152

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21262-3\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21262-3\" found in http://loinc.org|2.81\r\n"}]}

#613

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1418
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639154

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000009.11:g.139395147C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#614

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:863
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639156

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#615

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639158

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#616

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639160

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#617

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777","display":"ZFHX3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1503
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639162

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:777"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:777 (\"ZFHX3\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:777\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#618

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:960
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639164

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21269-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#619

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639166

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000016.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#620

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:03 GMT
last-modified:Thu, 16 Oct 2025 23:43:03 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639168

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#621

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1378
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639170

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_008816.3:p.G585S\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#622

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639172

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006885.4:c.1753G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#623

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777","display":"ZFHX3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1510
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639174

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:777"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:777 (\"ZFHX3\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:777\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#624

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2545
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639176

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:777"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:777 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:777\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#625

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1147
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639178

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21269-8\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21269-8\" found in http://loinc.org|2.81\r\n"}]}

#626

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1400
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639180

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000016.9:g.72992292C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#627

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235","display":"MSH2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1505
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639182

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7235"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7235 (\"MSH2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7235\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#628

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"1780982","display":"NM_000251.3(MSH2):c.1832del (p.Val611fs)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1619
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639184

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "1780982"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#1780982 (\"NM_000251.3(MSH2):c.1832del (p.Val611fs)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#1780982\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#629

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235","display":"MSH2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1508
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:04 GMT
last-modified:Thu, 16 Oct 2025 23:43:04 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639186

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7235"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7235 (\"MSH2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7235\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#630

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639188

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7235"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7235 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7235\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#631

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:879
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639190

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#632

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1563
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639192

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"SNV\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#633

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639194

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#634

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028","display":"NTHL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639196

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8028"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8028 (\"NTHL1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8028\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#635

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"962538","display":"NM_002528.7(NTHL1):c.728G>A (p.Trp243Ter)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1610
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639198

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "962538"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#962538 (\"NM_002528.7(NTHL1):c.728G>A (p.Trp243Ter)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#962538\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#636

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:05 GMT
last-modified:Thu, 16 Oct 2025 23:43:05 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639200

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#637

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1398
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639202

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_002519.2:p.Trp243Ter\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#638

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1563
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639204

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"SNV\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#639

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2701
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639206

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#640

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1375
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639208

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_002528.7:c.728G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#641

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028","display":"NTHL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639210

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8028"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8028 (\"NTHL1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8028\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#642

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639212

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8028"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:8028 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:8028\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#643

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1408
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:06 GMT
last-modified:Thu, 16 Oct 2025 23:43:06 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639214

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000016.10:g.2040196C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#644

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639216

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#645

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639218

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#646

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667","display":"insertion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639220

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000667 (\"insertion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000667\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#647

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639222

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#648

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355","display":"STAG2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639224

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11355"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11355 (\"STAG2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11355\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#649

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:957
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639226

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21276-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#650

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639228

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000023.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#651

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:07 GMT
last-modified:Thu, 16 Oct 2025 23:43:07 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639230

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#652

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1375
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639232

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_006594.3:p.S1178*\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#653

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667","display":"insertion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1562
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639234

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000667 (\"insertion\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000667\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#654

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2709
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639236

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0000667 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0000667\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#655

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1475
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639238

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006603.5:c.3530_3531insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#656

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355","display":"STAG2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1516
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639240

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11355"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11355 (\"STAG2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11355\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#657

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639242

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11355"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11355 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11355\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#658

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1144
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639244

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21276-3\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21276-3\" found in http://loinc.org|2.81\r\n"}]}

#659

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1538
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639246

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#660

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:08 GMT
last-modified:Thu, 16 Oct 2025 23:43:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639248

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#661

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:918
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639250

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#662

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882","display":"ATR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1508
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639252

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:882"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:882 (\"ATR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:882\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#663

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:964
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639254

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21256-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#664

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639256

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000003.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#665

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:955
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639258

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#666

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1438
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639260

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001184.4:c.2878_2879insAGTAA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#667

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882","display":"ATR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1501
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639262

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:882"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:882 (\"ATR\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:882\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#668

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2545
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:09 GMT
last-modified:Thu, 16 Oct 2025 23:43:09 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639264

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:882"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:882 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:882\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#669

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1144
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639266

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21256-5\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21256-5\" found in http://loinc.org|2.81\r\n"}]}

#670

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1493
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639268

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000003.11:g.142269071_142269072insTTACT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#671

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:879
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639270

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#672

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:871
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639273

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#673

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236","display":"EGFR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639275

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3236"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3236 (\"EGFR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3236\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#674

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639277

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#675

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1390
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:10 GMT
last-modified:Thu, 16 Oct 2025 23:43:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639279

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_005219.2:p.Leu858Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#676

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1380
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639281

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_005228.4:c.2573T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#677

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236","display":"EGFR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639283

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3236"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3236 (\"EGFR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3236\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#678

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639286

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3236"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3236 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3236\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#679

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1413
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639288

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000007.13:g.55259515T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#680

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261","display":"ROS1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1508
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639290

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10261"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10261 (\"ROS1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10261\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#681

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261","display":"ROS1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639292

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10261"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10261 (\"ROS1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10261\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#682

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2551
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639294

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10261"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:10261 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:10261\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#683

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26333-7","display":"Uncertain Significance"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:987
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639296

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26333-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Uncertain significance"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26333-7","display" : "Uncertain Significance"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26333-7 (\"Uncertain Significance\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26333-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#684

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4","display":"Associated phenotype"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
content-length:980
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:11 GMT
last-modified:Thu, 16 Oct 2025 23:43:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639298

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4","display" : "Associated phenotype"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"Associated phenotype\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#685

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"699346009","display":"Hereditary cancer-predisposing syndrome (disorder)"}],"text":"Hereditary cancer-predisposing syndrome"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
connection:keep-alive
content-length:1240
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639300

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "699346009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Hereditary neoplastic syndrome"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "699346009","display" : "Hereditary cancer-predisposing syndrome (disorder)"}],"text" : "Hereditary cancer-predisposing syndrome"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#699346009 (\"Hereditary cancer-predisposing syndrome (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#699346009\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#686

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26332-9","display":"Likely Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:972
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639302

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26332-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Likely pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26332-9","display" : "Likely Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26332-9 (\"Likely Pathogenic\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26332-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#687

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
connection:keep-alive
content-length:971
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639304

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"Level of evidence\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#688

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254637007","display":"Non-small cell lung cancer (disorder)"}],"text":"Non-small cell lung cancer"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1197
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639306

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254637007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Non-small cell lung cancer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254637007","display" : "Non-small cell lung cancer (disorder)"}],"text" : "Non-small cell lung cancer"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#254637007 (\"Non-small cell lung cancer (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#254637007\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#689

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT04919811","display":"NCT04919811"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1525
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639308

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT04919811"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://clinicaltrials.gov#NCT04919811 (\"NCT04919811\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://clinicaltrials.gov#NCT04919811\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}

#690

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:996
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639310

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6677-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#691

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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date:Thu, 16 Oct 2025 23:43:12 GMT
last-modified:Thu, 16 Oct 2025 23:43:12 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639313

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6677-4\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#692

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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cache-control:public, max-age=600
connection:keep-alive
content-length:992
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639315

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6677-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#693

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1865
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639318

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6677-4\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#694

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}],"text":"coding HGVS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-expose-headers:Content-Location, Location
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connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639320

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}],"text" : "coding HGVS"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#695

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A","display":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:899
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639322

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"NM_017617.5:c.5791G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#696

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5","display":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639324

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"NM_017617.5\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#697

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583","display":"missense_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639327

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001583"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001583 (\"missense_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001583\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#698

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T","display":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639329

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"NP_060087.3:p.A1931T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#699

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583","display":"missense_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639332

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001583"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001583 (\"missense_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001583\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#700

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:13 GMT
last-modified:Thu, 16 Oct 2025 23:43:13 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639334

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001583"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001583 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001583\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#701

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A","display":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:899
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639336

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"NM_006885.4:c.1753G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#702

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4","display":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639338

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"NM_006885.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#703

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S","display":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639340

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"NP_008816.3:p.G585S\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#704

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del","display":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639343

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"NM_000251.3:c.1832del\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#705

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589","display":"frameshift_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1571
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639347

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001589"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001589 (\"frameshift_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001589\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#706

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1388
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639349

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000251.3:c.1832del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#707

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589","display":"frameshift_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1571
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639351

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001589"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001589 (\"frameshift_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001589\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#708

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:14 GMT
last-modified:Thu, 16 Oct 2025 23:43:14 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639353

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001589"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001589 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001589\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#709

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A","display":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639355

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"NM_002528.7:c.728G>A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#710

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587","display":"stop_gained"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1564
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639357

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001587"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001587 (\"stop_gained\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001587\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#711

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter","display":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639359

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"NP_002519.2:p.Trp243Ter\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#712

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587","display":"stop_gained"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1564
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639361

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001587"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001587 (\"stop_gained\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001587\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#713

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2749
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639364

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001587"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001587 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001587\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#714

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT","display":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:994
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639366

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"NM_006603.5:c.3530_3531insGTGACTATTAATAT\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#715

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5","display":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639368

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"NM_006603.5\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#716

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*","display":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:887
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:15 GMT
last-modified:Thu, 16 Oct 2025 23:43:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639370

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"NP_006594.3:p.S1178*\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#717

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA","display":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:942
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639372

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"NM_001184.4:c.2878_2879insAGTAA\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#718

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4","display":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639374

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"NM_001184.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#719

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054","display":"loss_of_function_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639376

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO_0002054"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO_0002054 (\"loss_of_function_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO_0002054\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#720

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054","display":"loss_of_function_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639378

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO_0002054"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO_0002054 (\"loss_of_function_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO_0002054\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#721

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2725
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639380

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO_0002054"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO_0002054 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO_0002054\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#722

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G","display":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:899
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639382

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"NM_005228.4:c.2573T>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#723

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg","display":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:909
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639384

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"NP_005219.2:p.Leu858Arg\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#724

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886","display":"transcript_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:16 GMT
last-modified:Thu, 16 Oct 2025 23:43:16 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639386

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001886"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001886 (\"transcript_fusion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001886\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#725

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886","display":"transcript_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639388

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001886"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001886 (\"transcript_fusion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001886\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#726

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2717
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639390

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001886"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001886 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001886\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#727

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:943
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639392

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26203-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MSI-H"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26203-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#728

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1069
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639395

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#85147-7 (\"PD-L1 by clone 22C3 in Tissue by Immune stain Report\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#85147-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#729

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635","display":"CD274"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1509
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639397

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:17635"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:17635 (\"CD274\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:17635\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#730

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635","display":"CD274"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1516
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639399

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:17635"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:17635 (\"CD274\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:17635\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#731

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2551
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:17 GMT
last-modified:Thu, 16 Oct 2025 23:43:17 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639401

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:17635"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:17635 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:17635\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#732

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'; The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA26203-2\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA26203-2\" not found in http://loinc.org|2.81\r\n"}]}

#733

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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date:Thu, 16 Oct 2025 23:43:18 GMT
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x-request-id:238-2639405

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#734

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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#735

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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server:nginx
x-request-id:238-2639412

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA6576-8\"\r\n"}]}

#736

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1117
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639418

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Check \"http://loinc.org#LA26806-2\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Filter \"LIST = LL1040-6\": Code \"LA26806-2\" found in http://loinc.org|2.81\r\n"}]}

#737

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"309529002","display":"Lung mass (finding)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1113
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639421

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "309529002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Lung mass"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "309529002","display" : "Lung mass (finding)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#309529002 (\"Lung mass (finding)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#309529002\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#738

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1563
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639423

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002007 (\"MNV\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#739

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1559
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639425

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000032"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000032 (\"delins\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000032\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#740

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"CNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1556
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639427

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"CNV\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#741

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"424993006","display":"Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1177
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639429

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "424993006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Adenocarcinoma of lung, stage IV"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "424993006","display" : "Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#424993006 (\"Adenocarcinoma of lung, stage IV (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#424993006\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#742

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001565","display":"gene_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1564
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639431

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001565 (\"gene_fusion\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001565\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#743

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001576","display":"transcript_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1578
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639433

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001576"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001576 (\"transcript_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001576\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#744

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1013
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:20 GMT
last-modified:Thu, 16 Oct 2025 23:43:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639435

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#745

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic State"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:952
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639437

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic State"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"Allelic State\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#746

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5","display":"Genomic allele start-end"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:992
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639439

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5","display" : "Genomic allele start-end"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"Genomic allele start-end\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#747

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"398036000","display":"Familial hypercholesterolemia (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1186
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639441

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "398036000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Familial hypercholesterolemia (disorder)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "398036000","display" : "Familial hypercholesterolemia (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#398036000 (\"Familial hypercholesterolemia (disorder)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#398036000\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#748

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1574
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639443

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"copy_number_variation\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#749

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2709
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639445

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#750

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1574
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639447

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"copy_number_variation\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#751

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639449

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#752

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5489-1","name":"LOINCAnswersLL5489-1","title":"LOINC Answer Codes for LL5489-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1132
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:21 GMT
last-modified:Thu, 16 Oct 2025 23:43:21 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639451

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Check \"http://loinc.org#LA26320-4\"\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Filter \"LIST = LL5489-1\": Code \"LA26320-4\" found in http://loinc.org|2.81\r\n"}]}

#753

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:952
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639453

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26320-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#754

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1150
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639455

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26426-9\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26426-9\" found in http://loinc.org|2.81\r\n"}]}

#755

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:972
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639457

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26426-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#756

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639459

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#757

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036","display":"inversion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639461

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000036 (\"inversion\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000036\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#758

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2709
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639463

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:1000036 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:1000036\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#759

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036","display":"inversion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1569
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639465

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000036 (\"inversion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000036\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#760

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"441262","display":"APOE1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1581
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639467

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "441262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#441262 (\"APOE1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#441262\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#761

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613","display":"APOE"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1502
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639470

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:613 (\"APOE\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:613\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#762

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2537
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:22 GMT
last-modified:Thu, 16 Oct 2025 23:43:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639472

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:613 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:613\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#763

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613","display":"APOE"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1502
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639475

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:613 (\"APOE\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:613\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#764

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"441262","display":"APOE1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1581
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639477

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "441262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#441262 (\"APOE1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#441262\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#765

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00155","display":"CYP2D6*7.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639479

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00155"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00155 (\"CYP2D6*7.001\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00155\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#766

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625","display":"CYP2D6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639481

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2625"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2625 (\"CYP2D6\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2625\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#767

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639483

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2625"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:2625 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:2625\"\r\n16 16: 16ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#768

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625","display":"CYP2D6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639485

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2625"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2625 (\"CYP2D6\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2625\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#769

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00126","display":"CYP2D6*1.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639487

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00126 (\"CYP2D6*1.001\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00126\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#770

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00155","display":"CYP2D6*7.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639489

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00155"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00155 (\"CYP2D6*7.001\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00155\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#771

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00126","display":"CYP2D6*1.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639491

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00126 (\"CYP2D6*1.001\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00126\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#772

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"18474-7","display":"HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1048
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639493

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "18474-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 Ag [Presence] in Tissue by Immune stain"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "18474-7","display" : "HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#18474-7 (\"HER2 Ag [Presence] in Tissue by Immune stain\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#18474-7\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#773

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430","display":"ERBB2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1513
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:23 GMT
last-modified:Thu, 16 Oct 2025 23:43:23 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639495

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3430"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3430 (\"ERBB2\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3430\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#774

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639497

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3430"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3430 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3430\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#775

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430","display":"ERBB2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1513
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639499

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3430"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3430 (\"ERBB2\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3430\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#776

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1052
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639501

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "72382-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#72382-5 (\"HER2 [Units/volume] in Tissue by Immunoassay\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#72382-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#777

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7","display":"Variant ISCN"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:956
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639503

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7","display" : "Variant ISCN"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"Variant ISCN\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#778

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639505

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX,t(9;22)(q34;q4)"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX,t(9;22)(q34;q4) (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX,t(9;22)(q34;q4)\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#779

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"92818009","display":"Chronic myeloid leukemia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1134
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639507

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "92818009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Chronic myeloid leukemia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "92818009","display" : "Chronic myeloid leukemia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#92818009 (\"Chronic myeloid leukemia\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#92818009\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#780

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1482
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639509

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#781

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775","display":"FMR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639511

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3775"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3775 (\"FMR1\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3775\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#782

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:24 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639513

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3775"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3775 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3775\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#783

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775","display":"FMR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1512
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:25 GMT
last-modified:Thu, 16 Oct 2025 23:43:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639515

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3775"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3775 (\"FMR1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3775\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#784

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2","display":"Cytogenetic (chromosome) location"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1012
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:25 GMT
last-modified:Thu, 16 Oct 2025 23:43:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639517

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2","display" : "Cytogenetic (chromosome) location"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"Cytogenetic (chromosome) location\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#785

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_002024.5","display":"NM_002024.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:25 GMT
last-modified:Thu, 16 Oct 2025 23:43:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639519

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_002024.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_002024.5 (\"NM_002024.5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_002024.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#786

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]","display":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1057
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:25 GMT
last-modified:Thu, 16 Oct 2025 23:43:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639521

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#787

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1553
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:25 GMT
last-modified:Thu, 16 Oct 2025 23:43:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639523

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#788

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"44054006","display":"Diabetes mellitus type 2 (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1157
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:26 GMT
last-modified:Thu, 16 Oct 2025 23:43:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639525

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "44054006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Diabetes mellitus type II"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "44054006","display" : "Diabetes mellitus type 2 (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#44054006 (\"Diabetes mellitus type 2 (disorder)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#44054006\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#789

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565","display":"PABPN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:26 GMT
last-modified:Thu, 16 Oct 2025 23:43:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639527

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8565 (\"PABPN1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8565\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#790

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2540
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:26 GMT
last-modified:Thu, 16 Oct 2025 23:43:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639529

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:8565 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:8565\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#791

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565","display":"PABPN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1514
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:26 GMT
last-modified:Thu, 16 Oct 2025 23:43:26 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639531

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8565 (\"PABPN1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8565\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#792

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004643.4","display":"NM_004643.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1588
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639533

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_004643.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_004643.4 (\"NM_004643.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_004643.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#793

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]","display":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:904
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639535

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"NM_004643.3:c.3GGC[14]\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#794

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1393
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639537

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_004643.3:c.3GGC[14]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#795

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"503634","display":"NM_004643.3(PABPN1):c.3GGC[11] (p.Ala11_Gly12insAlaAlaAlaAla)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1637
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639539

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "503634"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#503634 (\"NM_004643.3(PABPN1):c.3GGC[11] (p.Ala11_Gly12insAlaAlaAlaAla)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#503634\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#796

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644","display":"AR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1507
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639541

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:644"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:644 (\"AR\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:644\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#797

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2545
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639543

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:644"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:644 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:644\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#798

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644","display":"AR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1500
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639545

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:644"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:644 (\"AR\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:644\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#799

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:866
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639547

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#800

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1373
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:27 GMT
last-modified:Thu, 16 Oct 2025 23:43:27 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639549

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000044.6:c.7G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#801

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met","display":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:899
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:28 GMT
last-modified:Thu, 16 Oct 2025 23:43:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639551

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"NP_000035.2:p.Val3Met\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#802

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1380
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:28 GMT
last-modified:Thu, 16 Oct 2025 23:43:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639553

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000035.2:p.Val3Met\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#803

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000044.3","display":"NM_000044.6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1595
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:28 GMT
last-modified:Thu, 16 Oct 2025 23:43:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639555

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000044.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000044.3 (\"NM_000044.6\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000044.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#804

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A","display":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:914
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:28 GMT
last-modified:Thu, 16 Oct 2025 23:43:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639557

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"NC_000019.8:g.1171707G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#805

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1403
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:28 GMT
last-modified:Thu, 16 Oct 2025 23:43:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639559

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000019.8:g.1171707G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#806

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2168
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:28 GMT
last-modified:Thu, 16 Oct 2025 23:43:28 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639562

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#807

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639564

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#444734003\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#808

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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x-request-id:238-2639566

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT03131453"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://clinicaltrials.gov#NCT03131453 (\"NCT03131453\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://clinicaltrials.gov#NCT03131453\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}

#809

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive (qualifier value)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-interpretation","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/observation-interpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.399"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.386"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.218"}],"version":"6.0.0-ballot3","name":"ObservationInterpretationCodes","title":"Observation Interpretation Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"A categorical assessment, providing a rough qualitative interpretation of the observation value,    such as “normal”/ “abnormal”,”low” / “high”, “better” / “worse”, “susceptible” / “resistant”, “expected”/ “not expected”.    The value set is intended to be for ANY use where coded representation of an interpretation is needed.   \r\n   \r\n   Notes:\r\n   \r\n   This is being communicated in v2.x in OBX-8 (Observation Interpretation), in v3 in ObservationInterpretation (CWE) in R1 (Representative Realm) and in FHIR in    Observation.interpretation. Historically these values come from the laboratory domain, and these codes are extensively    used. The value set binding is extensible, so codes outside the value set that are needed for interpretation concepts    (i.e. particular meanings) that are not included in the value set can be used, and these new codes may also be added to    the value set and published in a future version.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"v3-ObservationInterpretation","language":"en","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"url":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.5.83"}],"version":"3.0.0","name":"ObservationInterpretation","title":"ObservationInterpretation","status":"active","experimental":false,"date":"2019-03-20","publisher":"Health Level Seven International","contact":[{"telecom":[{"system":"url","value":"http://hl7.org"},{"system":"email","value":"hq@HL7.org"}]}],"description":"One or more codes providing a rough qualitative interpretation of the observation, such as \"normal\" / \"abnormal\", \"low\" / \"high\", \"better\" / \"worse\", \"resistant\" / \"susceptible\", \"expected\" / \"not expected\". The value set is intended to be for ANY use where coded representation of an interpretation is needed.","copyright":"This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html","caseSensitive":true,"hierarchyMeaning":"is-a","content":"complete","property":[{"extension":[{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry","valueCode":"antisymmetric"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity","valueCode":"transitive"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity","valueCode":"irreflexive"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable","valueBoolean":true},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind","valueCode":"Specializes"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName","valueString":"Generalizes"}],"code":"Specializes","description":"The child code is a more narrow version of the concept represented by the parent code.  I.e. 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Only included as a derived relationship.","type":"Coding"},{"code":"internalId","uri":"http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id","description":"The internal identifier for the concept in the HL7 Access database repository.","type":"code"},{"code":"notSelectable","uri":"http://hl7.org/fhir/concept-properties#notSelectable","description":"Indicates that the code is abstract - only intended to be used as a selector for other concepts","type":"boolean"},{"code":"status","uri":"http://hl7.org/fhir/concept-properties#status","description":"A property that indicates the status of the concept. One of active, experimental, deprecated, or retired.","type":"code"},{"code":"deprecationDate","uri":"http://hl7.org/fhir/concept-properties#deprecationDate","description":"The date at which a concept was deprecated. Concepts that are deprecated but not inactive can still be used, but their use is discouraged.","type":"dateTime"},{"code":"subsumedBy","uri":"http://hl7.org/fhir/concept-properties#parent","description":"The concept code of a parent concept","type":"code"}],"concept":[{"code":"_GeneticObservationInterpretation","display":"GeneticObservationInterpretation","definition":"Codes that specify interpretation of genetic analysis, such as \"positive\", \"negative\", \"carrier\", \"responsive\", etc.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22646"}]},{"code":"_ObservationInterpretationChange","display":"ObservationInterpretationChange","definition":"Interpretations of change of quantity and/or severity. At most one of B or W and one of U or D allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21090"}]},{"code":"_ObservationInterpretationExceptions","display":"ObservationInterpretationExceptions","definition":"Technical exceptions resulting in the inability to provide an interpretation. At most one allowed. Does not imply normality or severity.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21091"}]},{"code":"_ObservationInterpretationNormality","display":"ObservationInterpretationNormality","definition":"Interpretation of normality or degree of abnormality (including critical or \"alert\" level). Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21092"}]},{"code":"_ObservationInterpretationSusceptibility","display":"ObservationInterpretationSusceptibility","definition":"Interpretations of anti-microbial susceptibility testing results (microbiology). At most one allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21093"}]},{"code":"EX","display":"outside threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21634"}]},{"code":"HM","display":"Hold for Medical Review","definition":"Hold for Medical Review\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23790"}]},{"code":"ObservationInterpretationDetection","display":"ObservationInterpretationDetection","definition":"Interpretations of the presence or absence of a component / analyte or organism in a test or of a sign in a clinical observation. In keeping with laboratory data processing practice, these concepts provide a categorical interpretation of the \"meaning\" of the quantitative value for the same observation.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22805"}]},{"code":"ObservationInterpretationExpectation","display":"ObservationInterpretationExpectation","definition":"Interpretation of the observed result taking into account additional information (contraindicators) about the patient's situation. Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23723"}]},{"code":"OBX","display":"Interpretation qualifiers in separate OBX segments","definition":"Interpretation qualifiers in separate OBX segments\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23789"}]},{"code":"ReactivityObservationInterpretation","display":"ReactivityObservationInterpretation","definition":"Interpretations of the presence and level of reactivity of the specified component / analyte with the reagent in the performed laboratory test.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23568"}]},{"code":"CAR","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23559"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"Carrier","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This code is currently the same string as the print name for this concept and is inconsistent with the conventions being used for the other codes in the coding system, as it is a full word with initial capitalization, rather than an all upper case mnemonic. The recommendation from OO is to deprecate the code \"Carrier\" and to add \"CAR\" as the new active code representation for this concept.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"22647"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"B","display":"Better","definition":"The current result or observation value has improved compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10215"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"D","display":"Significant change down","definition":"The current result has decreased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10218"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"U","display":"Significant change up","definition":"The current result has increased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10217"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"W","display":"Worse","definition":"The current result or observation value has degraded compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10216"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"<","display":"Off scale low","definition":"The result is below the minimum detection limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Below analytical limit, low off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10226"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":">","display":"Off scale high","definition":"The result is above the maximum quantifiable limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Above analytical limit, high off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10227"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"AC","display":"Anti-complementary substances present","definition":"A valid result cannot be obtained for the specified component / analyte due to the presence of anti-complementary substances in the sample.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23564"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"IE","display":"Insufficient evidence","definition":"There is insufficient evidence that the species in question is a good target for therapy with the drug. A categorical interpretation is not possible.\r\n\r\n\\[Note: A MIC with \"IE\" and/or a comment may be reported (without an accompanying S, I or R-categorization).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23567"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"QCF","display":"Quality control failure","definition":"A result cannot be considered valid for the specified component / analyte or organism due to failure in the quality control testing component.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23565"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"TOX","display":"Cytotoxic substance present","definition":"A valid result cannot be obtained for the specified organism or cell line due to the presence of cytotoxic substances in the sample or culture.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23566"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"A","display":"Abnormal","definition":"The result or observation value is outside the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10208"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"N","display":"Normal","definition":"The result or observation value is within the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Applies to numeric or non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10207"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"I","display":"Intermediate","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\\]\r\n\r\n\\[Note 3: This class also indicates a \"buffer zone,\" to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\\]\r\n\r\n\\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10221"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"MS","display":"moderately susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10222"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NCL","display":"No CLSI defined breakpoint","definition":"Use when not enough clinical trial data published by the Clinical and Laboratory Standards Institutes (CLSI) is available to establish the breakpoints for susceptible / intermediate and resistant.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23886"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NS","display":"Non-susceptible","definition":"A category used for isolates for which only a susceptible interpretive criterion has been designated because of the absence or rare occurrence of resistant strains. Isolates that have MICs above or zone diameters below the value indicated for the susceptible breakpoint should be reported as non-susceptible.\r\n\r\nNOTE 1: An isolate that is interpreted as non-susceptible does not necessarily mean that the isolate has a resistance mechanism. It is possible that isolates with MICs above the susceptible breakpoint that lack resistance mechanisms may be encountered within the wild-type distribution subsequent to the time the susceptible-only breakpoint is set.\r\n\r\nNOTE 2: For strains yielding results in the \"nonsusceptible\" category, organism identification and antimicrobial susceptibility test results should be confirmed.\r\n\r\nSynonym: decreased susceptibility.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23557"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"R","display":"Resistant","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic failure. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as resistant by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10220"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"S","display":"Susceptible","definition":"Bacterial strain inhibited by in vitro concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic success. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Synonym (earlier term): Sensitive Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as susceptible by applying the appropriate breakpoints in a defined phenotypic system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10223"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"VS","display":"very susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10224"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"AA","display":"Critical abnormal","definition":"The result or observation value is outside a reference range or expected norm at a level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results. Analogous to critical/panic limits for numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10211"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"H","display":"High","definition":"The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Above high normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10210"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"L","display":"Low","definition":"The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Below low normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10209"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"HH","display":"Critical high","definition":"The result for a quantitative observation is above a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Above upper panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10213"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"H>"},{"code":"subsumedBy","valueCode":"HU"}]},{"code":"LL","display":"Critical low","definition":"The result for a quantitative observation is below a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Below lower panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10212"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"L<"},{"code":"subsumedBy","valueCode":"LU"}]},{"code":"HX","display":"above high threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21636"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"LX","display":"below low threshold","definition":"The numeric observation/test result is interpreted as being below the low threshold value for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A Total White Blood Cell Count falling below a protocol-defined threshold value of 3000/mm^3\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21635"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"H>","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'H' and 'HH'.\\]\r\n\r\n*Deprecation Comment:* The code 'H>' is being deprecated in order to align with the use of the code 'HU' for \"Very high\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'H>' is non-preferred, as this code is deprecated and on track to be retired; use code 'HU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23560"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"HU","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23742"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"E","display":"Equivocal","definition":"The test or procedure was successfully performed, but the results are borderline and can neither be declared positive / negative nor detected / not detected according to the current established criteria.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23732"},{"code":"subsumedBy","valueCode":"IND"}]},{"code":"L<","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'L' and 'LL'.\\]\r\n\r\n*Deprecation Comment:* The code 'L<' is being deprecated in order to align with the use of the code 'LU' for \"Very low\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'L<' is non-preferred, as this code is deprecated and on track to be retired; use code 'LU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23561"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"LU","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23743"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"ND","display":"Not detected","definition":"The presence of the specified component / analyte, organism or clinical sign could not be determined within the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23563"},{"code":"subsumedBy","valueCode":"NEG"}]},{"code":"IND","display":"Indeterminate","definition":"The specified component / analyte, organism or clinical sign could neither be declared positive / negative nor detected / not detected by the performed test or procedure.\r\n\r\n*Usage Note:* For example, if the specimen was degraded, poorly processed, or was missing the required anatomic structures, then \"indeterminate\" (i.e. \"cannot be determined\") is the appropriate response, not \"equivocal\".","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22807"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"NEG","display":"Negative","definition":"An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.\r\n\r\n\\[Note: Negative does not necessarily imply the complete absence of the specified item.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22808"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"POS","display":"Positive","definition":"A presence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22806"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"EXP","display":"Expected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Expected\" (e.g., presence of drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23724"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"UNE","display":"Unexpected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Unexpected\" (e.g., presence of non-prescribed drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23725"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"DET","display":"Detected","definition":"The measurement of the specified component / analyte, organism or clinical sign above the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23562"},{"code":"subsumedBy","valueCode":"POS"}]},{"code":"SYN-R","display":"Synergy - resistant","definition":"A category for isolates where the bacteria (e.g. enterococci) are not susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will not be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23621"},{"code":"subsumedBy","valueCode":"R"}]},{"code":"NR","display":"Non-reactive","definition":"An absence finding used to indicate that the specified component / analyte did not react measurably with the reagent.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23569"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"RR","display":"Reactive","definition":"A presence finding used to indicate that the specified component / analyte reacted with the reagent above the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23570"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"WR","display":"Weakly reactive","definition":"A weighted presence finding used to indicate that the specified component / analyte reacted with the reagent, but below the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23571"},{"code":"subsumedBy","valueCode":"RR"}]},{"code":"SDD","display":"Susceptible-dose dependent","definition":"A category that includes isolates with antimicrobial agent minimum inhibitory concentrations (MICs) that approach usually attainable blood and tissue levels and for which response rates may be lower than for susceptible isolates.\r\n\r\nReference: CLSI document M44-A2 2009 \"Method for antifungal disk diffusion susceptibility testing of yeasts; approved guideline - second edition\" - page 2.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23558"},{"code":"subsumedBy","valueCode":"S"}]},{"code":"SYN-S","display":"Synergy - susceptible","definition":"A category for isolates where the bacteria (e.g. enterococci) are susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23620"},{"code":"subsumedBy","valueCode":"S"}]}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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#810

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#811

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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2548
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639573

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3689"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3689 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3689\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#812

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689","display":"FGFR2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639575

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3689"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3689 (\"FGFR2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3689\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#813

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G","display":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639577

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"NC_000010.11:g.121498525T>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#814

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1418
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639579

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000010.11:g.121498525T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#815

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2114
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639582

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://snomed.info/sct#399223003\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"399223003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}

#816

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1177
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639584

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#399223003\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#817

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254837009","display":"Breast Cancer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1110
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:29 GMT
last-modified:Thu, 16 Oct 2025 23:43:29 GMT
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x-request-id:238-2639587

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254837009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant tumor of breast"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254837009","display" : "Breast Cancer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#254837009 (\"Breast Cancer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#254837009\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#818

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT01234567","display":"NCT01234567"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1532
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:30 GMT
last-modified:Thu, 16 Oct 2025 23:43:30 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639589

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT01234567"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://clinicaltrials.gov#NCT01234567 (\"NCT01234567\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://clinicaltrials.gov#NCT01234567\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}

#819

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639591

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000017.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#820

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1109
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639593

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30100-4\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}

#821

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:938
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639595

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30100-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#822

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1108
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639597

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Check \"http://loinc.org#LA26418-6\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Filter \"LIST = LL4048-6\": Code \"LA26418-6\" found in http://loinc.org|2.81\r\n"}]}

#823

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117","display":"SMN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1508
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639599

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11117"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11117 (\"SMN1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11117\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#824

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639601

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11117"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11117 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11117\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#825

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117","display":"SMN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639603

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11117"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11117 (\"SMN1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11117\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#826

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639605

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#827

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:937
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639607

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26418-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#828

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2256
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:32 GMT
last-modified:Thu, 16 Oct 2025 23:43:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639609

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'; The provided code 'http://loinc.org#LA26418-6 ('PCR')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26418-6 ('PCR')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26418-6\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26418-6\" not found in http://loinc.org|2.81\r\n"}]}

#829

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"5262007","display":"Spinal muscular atrophy (disorder)"}],"text":"Spinal muscular atrophy (SMA)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1190
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639611

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "5262007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Spinal muscular atrophy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "5262007","display" : "Spinal muscular atrophy (disorder)"}],"text" : "Spinal muscular atrophy (SMA)"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#5262007 (\"Spinal muscular atrophy (disorder)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#5262007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#830

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000001.10:g.86852621A>G","display":"NC_000001.10:g.86852621A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:924
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639613

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000001.10:g.86852621A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000001.10:g.86852621A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G (\"NC_000001.10:g.86852621A>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#831

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic Ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639615

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic Ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"Genomic Ref allele [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#832

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic Alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639617

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic Alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"Genomic Alt allele [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#833

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1183
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639619

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30100-4\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}

#834

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:996
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639621

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30100-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#835

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Variant exact start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:964
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639623

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Variant exact start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#836

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}],"text":"Population allele frequency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:975
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639625

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}],"text" : "Population allele frequency"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#837

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction","code":"HIGH","display":"High"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1868
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639628

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "code","valueCode" : "HIGH"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH (\"High\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction\"\r\n"}]}

#838

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395525.1","display":"NM_001395525.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1600
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639630

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001395525.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001395525.1 (\"NM_001395525.1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001395525.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#839

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575","display":"splice_donor_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:33 GMT
last-modified:Thu, 16 Oct 2025 23:43:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639632

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001575"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001575 (\"splice_donor_variant\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001575\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#840

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1570
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639634

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#841

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2749
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639636

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001575"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001575 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001575\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#842

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639638

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#843

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575","display":"splice_donor_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639640

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001575"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001575 (\"splice_donor_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001575\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#844

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1567
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639642

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#845

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C","display":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:897
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639644

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"NM_001366781.1:c.90T>C\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#846

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1385
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639646

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001366781.1:c.90T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#847

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001366781.1","display":"NM_001366781.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1600
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639648

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001366781.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001366781.1 (\"NM_001366781.1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001366781.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#848

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819","display":"synonymous_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1571
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639650

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001819"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001819 (\"synonymous_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001819\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#849

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2749
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639652

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001819"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001819 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001819\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#850

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819","display":"synonymous_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1571
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:34 GMT
last-modified:Thu, 16 Oct 2025 23:43:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639654

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001819"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001819 (\"synonymous_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001819\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#851

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C","display":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:914
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639656

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"NM_001395543.1:c.-171T>C\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#852

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1403
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639658

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001395543.1:c.-171T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#853

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395543.1","display":"NM_001395543.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1607
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639660

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001395543.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001395543.1 (\"NM_001395543.1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001395543.1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#854

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623","display":"5_prime_UTR_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1572
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639662

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001623 (\"5_prime_UTR_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001623\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#855

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639664

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001623 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001623\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#856

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623","display":"5_prime_UTR_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1572
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639666

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001623 (\"5_prime_UTR_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001623\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#857

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395544.1","display":"NM_001395544.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1600
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639668

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001395544.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001395544.1 (\"NM_001395544.1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001395544.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#858

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1574
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639670

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#859

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2757
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639672

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}

#860

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1574
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:35 GMT
last-modified:Thu, 16 Oct 2025 23:43:35 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639674

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#861

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0009061","display":"cystic fibrosis"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1640
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639676

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "code","valueCode" : "MONDO:0009061"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://purl.obolibrary.org/obo/mondo.owl#MONDO:0009061 (\"cystic fibrosis\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://purl.obolibrary.org/obo/mondo.owl#MONDO:0009061\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://purl.obolibrary.org/obo/mondo.owl\"\r\n"}]}

#862

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1619
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639678

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"Autosomal recessive inheritance\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://human-phenotype-ontology.org\"\r\n"}]}

#863

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2837
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639680

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot' because the code system http://human-phenotype-ontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot' because the code system http://human-phenotype-ontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: CodeSystem not found: \"http://human-phenotype-ontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: CodeSystem not found: http://human-phenotype-ontology.org\r\n"}]}

#864

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1619
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639682

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"Autosomal recessive inheritance\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://human-phenotype-ontology.org\"\r\n"}]}

#865

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118","display":"SMN2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639684

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11118"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11118 (\"SMN2\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11118\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#866

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2543
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639686

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11118"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11118 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11118\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}

#867

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118","display":"SMN2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1515
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639688

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11118"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11118 (\"SMN2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11118\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#868

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8","display":"Allelic frequency in Population"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1013
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639690

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8","display" : "Allelic frequency in Population"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"Allelic frequency in Population\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#869

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:946
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:36 GMT
last-modified:Thu, 16 Oct 2025 23:43:36 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639692

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26806-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#870

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1556
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639694

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"SNV\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#871

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1563
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639696

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002007 (\"MNV\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002007\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#872

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1566
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639698

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000032"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000032 (\"delins\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000032\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#873

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1574
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639700

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"copy_number_variation\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#874

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8"}],"text":"Genetic variation clinical significance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:994
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639702

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}],"text" : "Genetic variation clinical significance"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#875

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4"}],"text":"Predicted phenotype"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:949
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639704

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}],"text" : "Predicted phenotype"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#876

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405501007","display":"Malignant hyperthermia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1132
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639707

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405501007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant hyperthermia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405501007","display" : "Malignant hyperthermia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#405501007 (\"Malignant hyperthermia\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#405501007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#877

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:994
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639710

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"Genomic source class [Type]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#878

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000019.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639712

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000019.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000019.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000019.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#879

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Genomic allele start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:965
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639714

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Genomic allele start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#880

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2D6_*1/*1","display":"CYP2D6 *1/*1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1522
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639716

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2D6_*1/*1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2D6_*1/*1 (\"CYP2D6 *1/*1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2D6_*1/*1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#881

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C19_*1/*2","display":"CYP2C19 *1/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1519
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:37 GMT
last-modified:Thu, 16 Oct 2025 23:43:37 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639718

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C19_*1/*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C19_*1/*2 (\"CYP2C19 *1/*2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C19_*1/*2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#882

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39","display":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1905
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639720

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39 (\"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#883

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639722

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.9 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.9\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#884

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:945
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639724

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA9633-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#885

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA Change Type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:965
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639726

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA Change Type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"DNA Change Type\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#886

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000007.13"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639728

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000007.13"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000007.13 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000007.13\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#887

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic Source Class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:980
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639730

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic Source Class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"Genomic Source Class\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#888

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}],"text":"Variant inner start and end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:982
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639732

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}],"text" : "Variant inner start and end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#889

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1124
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639734

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA9633-4\"\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}

#890

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000007.14"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639736

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000007.14"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000007.14 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000007.14\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#891

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3","display":"Genomic Structural Variant copy Number"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1027
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639738

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3","display" : "Genomic Structural Variant copy Number"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"Genomic Structural Variant copy Number\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#892

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"480167","display":"Lapatinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1074
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639740

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "480167"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "lapatinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "480167","display" : "Lapatinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#480167 (\"Lapatinib\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#480167\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#893

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"443968007","display":"Sequencing of entire coding region of gene (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1228
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:38 GMT
last-modified:Thu, 16 Oct 2025 23:43:38 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639742

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "443968007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Sequencing of entire coding region of gene (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "443968007","display" : "Sequencing of entire coding region of gene (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#443968007 (\"Sequencing of entire coding region of gene (procedure)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#443968007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#894

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"a"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639744

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "a"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "a"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#a (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#a\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#895

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94231-8","display":"G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1108
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639746

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94231-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94231-8","display" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94231-8 (\"G6PD gene full mutation analysis in Blood or Tissue by Sequencing\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94231-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#896

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1689
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639748

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#897

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405825005","display":"Molecular genetic test (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1168
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639750

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405825005"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Molecular genetic test (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405825005","display" : "Molecular genetic test (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#405825005 (\"Molecular genetic test (procedure)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#405825005\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#898

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"108252007","display":"Laboratory procedure"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639752

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "108252007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Laboratory procedure"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "108252007","display" : "Laboratory procedure"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#108252007 (\"Laboratory procedure\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#108252007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#899

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13298-5","display":"HLA-A [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:949
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639754

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13298-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13298-5","display" : "HLA-A [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#13298-5 (\"HLA-A [Type]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#13298-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#900

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"258564008","display":"Buccal smear sample"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1123
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639756

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "258564008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal smear sample"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "258564008","display" : "Buccal smear sample"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#258564008 (\"Buccal smear sample\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#258564008\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#901

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122610009","display":"Specimen from lung obtained by biopsy (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1192
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639758

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122610009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Specimen from lung obtained by biopsy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122610009","display" : "Specimen from lung obtained by biopsy (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#122610009 (\"Specimen from lung obtained by biopsy (specimen)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#122610009\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#902

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"129314006","display":"Biopsy - action"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1111
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639760

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "129314006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Biopsy - action"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "129314006","display" : "Biopsy - action"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#129314006 (\"Biopsy - action\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#129314006\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#903

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"119297000","display":"Blood specimen (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1130
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639762

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "119297000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "119297000","display" : "Blood specimen (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#119297000 (\"Blood specimen (specimen)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#119297000\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#904

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"418622002","display":"Taking oral swab (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1150
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639764

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "418622002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Taking oral swab (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "418622002","display" : "Taking oral swab (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#418622002 (\"Taking oral swab (procedure)\")]\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#418622002\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#905

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"261063000","display":"Buccal space"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1102
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639766

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "261063000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal space"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "261063000","display" : "Buccal space"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#261063000 (\"Buccal space\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#261063000\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#906

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"3341006","display":"Right lung structure (body structure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1135
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:39 GMT
last-modified:Thu, 16 Oct 2025 23:43:39 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639768

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "3341006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Right lung"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "3341006","display" : "Right lung structure (body structure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#3341006 (\"Right lung structure (body structure)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#3341006\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#907

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1124
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:40 GMT
last-modified:Thu, 16 Oct 2025 23:43:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639770

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Check \"http://loinc.org#LA26421-0\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Filter \"LIST = LL4049-4\": Code \"LA26421-0\" found in http://loinc.org|2.81\r\n"}]}

#908

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0","display":"Consider alternative medication"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2368
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:40 GMT
last-modified:Thu, 16 Oct 2025 23:43:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639772

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26421-0 ('Consider alternative medication')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0","display" : "Consider alternative medication"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26421-0 ('Consider alternative medication')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26421-0 (\"Consider alternative medication\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26421-0\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26421-0\" not found in http://loinc.org|2.81\r\n"}]}

#909

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26422-8","display":"Decrease dose"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2287
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:40 GMT
last-modified:Thu, 16 Oct 2025 23:43:40 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639774

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26422-8 ('Decrease dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26422-8","display" : "Decrease dose"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26422-8 ('Decrease dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26422-8 (\"Decrease dose\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26422-8\"\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26422-8\" not found in http://loinc.org|2.81\r\n"}]}

#910

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639776

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#911

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639778

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#912

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639780

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#913

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639782

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#914

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639784

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#915

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639786

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#916

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639788

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#917

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639790

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#918

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639792

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#919

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639794

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#920

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639796

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#921

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:54 GMT
last-modified:Thu, 16 Oct 2025 23:43:54 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639798

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#922

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639800

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#923

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639802

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#924

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639804

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#925

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639806

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#926

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639808

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#927

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639810

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#928

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639812

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#929

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639814

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#930

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639816

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#931

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639818

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#932

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639820

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#933

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639822

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#934

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:55 GMT
last-modified:Thu, 16 Oct 2025 23:43:55 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639824

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#935

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639826

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#936

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639828

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#937

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639830

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#938

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639832

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#939

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639834

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#940

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639836

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#941

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639838

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#942

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639840

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#943

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639842

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#944

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639844

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#945

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639846

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#946

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639848

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#947

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:56 GMT
last-modified:Thu, 16 Oct 2025 23:43:56 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639850

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#948

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639852

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#949

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639854

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#950

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639856

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#951

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639858

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#952

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1583
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639860

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#953

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639862

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#954

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639864

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#955

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639866

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#956

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639868

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#957

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639870

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#958

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639872

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#959

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639874

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#960

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:57 GMT
last-modified:Thu, 16 Oct 2025 23:43:57 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639876

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#961

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639878

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#962

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639880

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#963

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639882

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#964

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639884

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#965

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639886

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#966

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639888

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#967

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639890

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#968

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639892

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#969

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639894

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#970

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639896

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#971

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639898

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#972

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639900

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#973

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:58 GMT
last-modified:Thu, 16 Oct 2025 23:43:58 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639902

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#974

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639904

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#975

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639906

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#976

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639908

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#977

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639910

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#978

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639912

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#979

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639914

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#980

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639916

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#981

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639918

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#982

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639920

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#983

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639922

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#984

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639924

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#985

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:43:59 GMT
last-modified:Thu, 16 Oct 2025 23:43:59 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639926

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#986

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1619
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639928

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#987

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639930

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#988

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639932

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#989

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639934

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#990

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639936

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#991

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639938

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#992

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1577
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639940

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#993

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/CodeSystem/medicationknowledge-status","code":"active"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:977
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:00 GMT
last-modified:Thu, 16 Oct 2025 23:44:00 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639943

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/CodeSystem/medicationknowledge-status"},{"name" : "code","valueCode" : "active"},{"name" : "version","valueString" : "5.0.0"},{"name" : "display","valueString" : "Active"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status|5.0.0 (from hl7.fhir.r5.core#5.0.0)\" (content = complete)\r\n"}]}

#994

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1607
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:01 GMT
last-modified:Thu, 16 Oct 2025 23:44:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639945

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#995

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1584
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:01 GMT
last-modified:Thu, 16 Oct 2025 23:44:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639947

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#996

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1617
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:01 GMT
last-modified:Thu, 16 Oct 2025 23:44:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639949

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#997

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1587
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:01 GMT
last-modified:Thu, 16 Oct 2025 23:44:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639951

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#998

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1580
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:01 GMT
last-modified:Thu, 16 Oct 2025 23:44:01 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639953

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#999

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org"}]}}}]}
422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:473
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:07 GMT
server:nginx
x-request-id:238-2639958

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The value set '' expansion has too many codes to display (&gt;10000)</p></div>"},"issue" : [{"severity" : "error","code" : "too-costly","details" : {"text" : "The value set '' expansion has too many codes to display (>10000)"},"diagnostics" : "0 0 : start\r\n0 0: not in cache\r\n0 0: tx-op\r\n0 0: 0ms start working\r\n0 0: 0ms compose #1\r\n"}]}

#1000

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"draft"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1}],"url":"http://hl7.org/fhir/ValueSet/observation-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.396"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.383"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.216"}],"version":"6.0.0-ballot3","name":"LOINCCodes","title":"LOINC Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all LOINC codes","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}}]}
200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:116824
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:08 GMT
last-modified:Thu, 16 Oct 2025 23:44:08 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639960

{"resourceType" : "ValueSet","meta" : {"lastUpdated" : "2025-04-01T12:16:37.966+11:00","profile" : ["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"url" : "http://hl7.org/fhir/ValueSet/observation-codes","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.3.396"},{"use" : "old","system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.3.383"},{"use" : "old","system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.2.216"}],"version" : "6.0.0-ballot3","name" : "LOINCCodes","title" : "LOINC Codes","status" : "draft","experimental" : false,"jurisdiction" : [{"coding" : [{"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm","code" : "001","display" : "World"}]}],"expansion" : {"identifier" : "urn:uuid:294f9e17-6688-4eb1-a67f-b339f6c88474","timestamp" : "2025-10-16T23:44:07.625Z","offset" : 0,"parameter" : [{"name" : "limitedExpansion","valueBoolean" : true},{"name" : "displayLanguage","valueCode" : "en"},{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "100000-9","display" : "Health informatics pioneer and the father of LOINC"},{"system" : "http://loinc.org","code" : "100001-7","display" : "Health informatics pioneer and cofounder of LOINC"},{"system" : "http://loinc.org","code" : "100002-5","display" : "Specimen care is maintained"},{"system" : "http://loinc.org","code" : "100003-3","display" : "Team communication is maintained throughout care"},{"system" : "http://loinc.org","code" : "100004-1","display" : "Demonstrates knowledge of the expected psychosocial responses to the procedure"},{"system" : "http://loinc.org","code" : "100005-8","display" : "Demonstrates knowledge of nutritional management related to the procedure"},{"system" : "http://loinc.org","code" : "100006-6","display" : "Demonstrates knowledge of medication management"},{"system" : "http://loinc.org","code" : "100007-4","display" : "Demonstrates knowledge of pain management"},{"system" : "http://loinc.org","code" : "10000-8","display" : "R wave duration in lead AVR"},{"system" : "http://loinc.org","code" : "100008-2","display" : "Demonstrates knowledge of wound management"},{"system" : "http://loinc.org","code" : "100009-0","display" : "Demonstrates knowledge of the procedure and expected results"},{"system" : "http://loinc.org","code" : "100010-8","display" : "No injury related to procedure equipment, medical supplies, or instrumentation"},{"system" : "http://loinc.org","code" : "100011-6","display" : "No injury related to an electrical source"},{"system" : "http://loinc.org","code" : "100012-4","display" : "Participates in decisions affecting the patient's plan of care"},{"system" : "http://loinc.org","code" : "100013-2","display" : "Participates in the discharge process"},{"system" : "http://loinc.org","code" : "100014-0","display" : "Psychosocial health is maintained at or improved from baseline"},{"system" : "http://loinc.org","code" : "100015-7","display" : "No injury related to positioning due to care or procedure"},{"system" : "http://loinc.org","code" : "10001-6","display" : "R wave duration in lead I"},{"system" : "http://loinc.org","code" : "100016-5","display" : "No injury related to a laser source"},{"system" : "http://loinc.org","code" : "100017-3","display" : "Perioperative nursing data set outcomes panel [PNDS]"},{"system" : "http://loinc.org","code" : "100018-1","display" : "Hospice care Note"},{"system" : "http://loinc.org","code" : "100019-9","display" : "ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100020-7","display" : "GNA11 gene mutations found [Identifier] in Blood or Tissue by 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#1002

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Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:379
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:08 GMT
server:nginx
x-request-id:238-2639965

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}

#1003

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"condition-inheritance-mode-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs","version":"4.0.0-ballot","name":"ConditionInheritanceModeVS","title":"Condition Inheritance Patterns","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific transmission patterns of a condition in a pedigree","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:379
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:08 GMT
server:nginx
x-request-id:238-2639968

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}

#1004

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.genenames.org"}]}}}]}
422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:357
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:10 GMT
server:nginx
x-request-id:238-2639971

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.genenames.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.genenames.org"}}]}

#1005

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"hgnc-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs","version":"4.0.0-ballot","name":"HGNCVS","title":"HUGO Gene Nomenclature Committee Gene Names (HGNC)","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"This value set includes all HGNC Codes, which includes multiple code systems. In this guide, Gene IDs from HGNC are used as CodeableConcepts, which must be sent with the HGNC gene ID including the prefix 'HGNC:' as the code and the HGNC 'gene symbol' as display. CAUTION: HGNC also indexes gene groups by numeric ID (without a prefix), and older systems may send HGNC gene IDs without the prefix, so care must be taken to confirm alignment. We have separately included the genegroup code system to draw attention to this ambiguity and potential error.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.genenames.org"},{"system":"http://www.genenames.org/genegroup"}]}}}]}
422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:357
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:10 GMT
server:nginx
x-request-id:238-2639975

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.genenames.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.genenames.org"}}]}

#1006

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:819
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:10 GMT
last-modified:Thu, 16 Oct 2025 23:44:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639977

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1007

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}}]}
200
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access-control-allow-origin:*
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cache-control:public, max-age=600
connection:keep-alive
content-length:872
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:10 GMT
last-modified:Thu, 16 Oct 2025 23:44:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639979

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:0dacb50b-deab-4517-8b8e-6c4876456b18","timestamp" : "2025-10-16T23:44:10.498Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA14032-9","display" : "NCBI Build 34"},{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"},{"system" : "http://loinc.org","code" : "LA14030-3","display" : "NCBI Build 36.1"},{"system" : "http://loinc.org","code" : "LA14031-1","display" : "NCBI Build 35"},{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}}

#1008

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2413
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:10 GMT
last-modified:Thu, 16 Oct 2025 23:44:10 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639981

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:c3ad1135-ef3d-41b7-8dde-40e53a5276ee","timestamp" : "2025-10-16T23:44:10.587Z","total" : 24,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA21254-0","display" : "Chromosome 1"},{"system" : "http://loinc.org","code" : "LA21255-7","display" : "Chromosome 2"},{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"},{"system" : "http://loinc.org","code" : "LA21257-3","display" : "Chromosome 4"},{"system" : "http://loinc.org","code" : "LA21258-1","display" : "Chromosome 5"},{"system" : "http://loinc.org","code" : "LA21259-9","display" : "Chromosome 6"},{"system" : "http://loinc.org","code" : "LA21260-7","display" : "Chromosome 7"},{"system" : "http://loinc.org","code" : "LA21261-5","display" : "Chromosome 8"},{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"},{"system" : "http://loinc.org","code" : "LA21263-1","display" : "Chromosome 10"},{"system" : "http://loinc.org","code" : "LA21264-9","display" : "Chromosome 11"},{"system" : "http://loinc.org","code" : "LA21265-6","display" : "Chromosome 12"},{"system" : "http://loinc.org","code" : "LA21266-4","display" : "Chromosome 13"},{"system" : "http://loinc.org","code" : "LA21267-2","display" : "Chromosome 14"},{"system" : "http://loinc.org","code" : "LA21268-0","display" : "Chromosome 15"},{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"},{"system" : "http://loinc.org","code" : "LA21270-6","display" : "Chromosome 17"},{"system" : "http://loinc.org","code" : "LA21271-4","display" : "Chromosome 18"},{"system" : "http://loinc.org","code" : "LA21272-2","display" : "Chromosome 19"},{"system" : "http://loinc.org","code" : "LA21273-0","display" : "Chromosome 20"},{"system" : "http://loinc.org","code" : "LA21274-8","display" : "Chromosome 21"},{"system" : "http://loinc.org","code" : "LA21275-5","display" : "Chromosome 22"},{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"},{"system" : "http://loinc.org","code" : "LA21277-1","display" : "Chromosome Y"}]}}

#1009

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:11 GMT
last-modified:Thu, 16 Oct 2025 23:44:11 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639983

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1010

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}}]}
200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:821
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:15 GMT
last-modified:Thu, 16 Oct 2025 23:44:15 GMT
pragma:no-cache
server:nginx
x-request-id:238-2639985

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:cb9ea3d0-ef13-4ae0-a030-eac2c539781a","timestamp" : "2025-10-16T23:44:15.925Z","total" : 4,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"},{"system" : "http://loinc.org","code" : "LA26427-7","display" : "Family DNA"},{"system" : "http://loinc.org","code" : "LA26428-5","display" : "Family history"},{"system" : "http://loinc.org","code" : "LA26429-3","display" : "Inferred from population data"}]}}

#1011

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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#1012

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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server:nginx
x-request-id:238-2639991

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#1013

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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#1014

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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#1015

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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date:Thu, 16 Oct 2025 23:44:18 GMT
server:nginx
x-request-id:238-2640000

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#1016

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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server:nginx
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#1017

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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422
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date:Thu, 16 Oct 2025 23:44:19 GMT
server:nginx
x-request-id:238-2640006

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#1018

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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server:nginx
x-request-id:238-2640009

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#1019

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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last-modified:Thu, 16 Oct 2025 23:44:20 GMT
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server:nginx
x-request-id:238-2640012

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:4bdfb178-383e-4dc7-b1df-167b30666e6b","timestamp" : "2025-10-16T23:44:20.704Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}

#1020

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:854
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:20 GMT
last-modified:Thu, 16 Oct 2025 23:44:20 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640014

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:b9d9704f-d065-457e-8e6f-93ff21d5261b","timestamp" : "2025-10-16T23:44:20.786Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : true},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "version","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}

#1021

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:782
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640017

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:0319f081-45c4-4b36-92a1-4d2f7f8c0b81","timestamp" : "2025-10-16T23:44:22.241Z","total" : 4,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"},{"system" : "http://loinc.org","code" : "LA9634-2","display" : "Absent"},{"system" : "http://loinc.org","code" : "LA18198-4","display" : "No call"},{"system" : "http://loinc.org","code" : "LA11884-6","display" : "Indeterminate"}]}}

#1022

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:790
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640019

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1023

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:760
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640021

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:ef09b262-e713-4d48-b433-4a3b07ec63fe","timestamp" : "2025-10-16T23:44:22.411Z","total" : 3,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"},{"system" : "http://loinc.org","code" : "LA30101-2","display" : "0-based character counting"},{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}}

#1024

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}
422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:371
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
server:nginx
x-request-id:238-2640024

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.sequenceontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.sequenceontology.org"}}]}

#1025

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-ballot","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}
422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:371
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
server:nginx
x-request-id:238-2640027

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.sequenceontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.sequenceontology.org"}}]}

#1026

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1111
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640029

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:920fddb7-4c6d-43cb-b018-8e4495c33808","timestamp" : "2025-10-16T23:44:22.674Z","total" : 8,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"},{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"},{"system" : "http://loinc.org","code" : "LA10429-1","display" : "Fetal"},{"system" : "http://loinc.org","code" : "LA18194-3","display" : "Likely germline"},{"system" : "http://loinc.org","code" : "LA18195-0","display" : "Likely somatic"},{"system" : "http://loinc.org","code" : "LA18196-8","display" : "Likely fetal"},{"system" : "http://loinc.org","code" : "LA18197-6","display" : "Unknown genomic origin"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"}]}}

#1027

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640031

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:ccd81a24-2d85-4a6a-9058-372191c1f0f6","timestamp" : "2025-10-16T23:44:22.752Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6703-8","display" : "Heteroplasmic"},{"system" : "http://loinc.org","code" : "LA6704-6","display" : "Homoplasmic"},{"system" : "http://loinc.org","code" : "LA6705-3","display" : "Homozygous"},{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"},{"system" : "http://loinc.org","code" : "LA6707-9","display" : "Hemizygous"}]}}

#1028

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:856
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640033

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:e4b50fa1-d55c-4a75-aa52-58d50151e238","timestamp" : "2025-10-16T23:44:22.839Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"},{"system" : "http://loinc.org","code" : "LA26321-2","display" : "Paternal"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"},{"system" : "http://loinc.org","code" : "LA4489-6","display" : "Unknown"},{"system" : "http://loinc.org","code" : "LA30680-5","display" : "Parental"}]}}

#1029

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2420
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:22 GMT
last-modified:Thu, 16 Oct 2025 23:44:22 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640035

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:1b81fdb5-d945-4b7a-b234-3d315a87e569","timestamp" : "2025-10-16T23:44:22.940Z","total" : 23,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"},{"system" : "http://loinc.org","code" : "LA26399-8","display" : "Oligo aCGH"},{"system" : "http://loinc.org","code" : "LA26400-4","display" : "SNP array"},{"system" : "http://loinc.org","code" : "LA26401-2","display" : "BAC aCGH"},{"system" : "http://loinc.org","code" : "LA26402-0","display" : "Curated"},{"system" : "http://loinc.org","code" : "LA26403-8","display" : "Digital array"},{"system" : "http://loinc.org","code" : "LA26404-6","display" : "FISH"},{"system" : "http://loinc.org","code" : "LA26405-3","display" : "Gene expression array"},{"system" : "http://loinc.org","code" : "LA26406-1","display" : "Karyotyping"},{"system" : "http://loinc.org","code" : "LA26407-9","display" : "MAPH"},{"system" : "http://loinc.org","code" : "LA26408-7","display" : "MALDI-TOF"},{"system" : "http://loinc.org","code" : "LA26808-8","display" : "Merging"},{"system" : "http://loinc.org","code" : "LA26414-5","display" : "Multiple complete digestion"},{"system" : "http://loinc.org","code" : "LA26415-2","display" : "MLPA"},{"system" : "http://loinc.org","code" : "LA26417-8","display" : "Optical mapping"},{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"},{"system" : "http://loinc.org","code" : "LA26419-4","display" : "qPCR (real-time PCR)"},{"system" : "http://loinc.org","code" : "LA26420-2","display" : "ROMA"},{"system" : "http://loinc.org","code" : "LA26809-6","display" : "Denaturing high-pressure liquid chromatography (DHPLC)"},{"system" : "http://loinc.org","code" : "LA26810-4","display" : "DNA hybridization"},{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"},{"system" : "http://loinc.org","code" : "LA26812-0","display" : "Single-stranded conformational polymorphism (SSCP)"},{"system" : "http://loinc.org","code" : "LA26813-8","display" : "Restriction fragment length polymorphism (RFLP)"}]}}

#1030

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1564
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:24 GMT
last-modified:Thu, 16 Oct 2025 23:44:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640037

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002072\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#1031

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1557
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:24 GMT
last-modified:Thu, 16 Oct 2025 23:44:24 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640039

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#1032

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1564
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:25 GMT
last-modified:Thu, 16 Oct 2025 23:44:25 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640041

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001537\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#1033

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:806
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640044

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1034

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:834
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640046

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1035

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640048

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1036

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:806
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640050

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1037

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:815
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640052

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1038

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:823
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640054

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1039

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:853
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640056

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48000-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1040

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:813
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640058

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1041

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:810
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640060

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1042

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:803
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:32 GMT
last-modified:Thu, 16 Oct 2025 23:44:32 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640062

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1043

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:808
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640064

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1044

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:823
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640066

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1045

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:807
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640068

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1046

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:795
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640070

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1047

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:806
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640072

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1048

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:815
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640074

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1049

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:815
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640076

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1050

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:801
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640078

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1051

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640080

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1052

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:813
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640082

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1053

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640084

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1054

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640086

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81301-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1055

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:814
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:33 GMT
last-modified:Thu, 16 Oct 2025 23:44:33 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640088

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1056

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:805
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640090

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1057

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640092

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1058

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:804
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640094

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1059

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640096

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1060

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:827
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640098

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1061

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:807
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640100

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1062

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:798
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640102

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1063

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:823
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640104

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94186-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1064

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640106

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82309-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1065

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:813
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640108

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#1066

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:827
content-type:application/fhir+json
date:Thu, 16 Oct 2025 23:44:34 GMT
last-modified:Thu, 16 Oct 2025 23:44:34 GMT
pragma:no-cache
server:nginx
x-request-id:238-2640110

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}