#1

GET https://tx.fhir.org/r5/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher

200
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date:Fri, 19 Dec 2025 22:11:39 GMT
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{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20251208221453.000Z. Server version 4.0.7 built 20251208221453.000Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>subsumes: see OperationDefinition/fso-subsumes</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.8.0"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-4.0.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-12-19T22:11:39.598Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "4.0.7","releaseDate" : "2025-12-08T22:14:53.000Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "subsumes","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-subsumes"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}

#2

GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0
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User-Agent: fhir/publisher

200
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date:Fri, 19 Dec 2025 22:11:39 GMT
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{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r5/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2025-12-19T22:11:39.879Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "5.0.0"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/account-aggregate","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-balance-term","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-billing-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-function","version" : [{"code" : 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[{"code" : "2025"}]},{"uri" : "https://fevir.net/sevco","version" : [{"code" : "2.0"}]},{"uri" : "https://fhir-terminology.ohdsi.org","version" : [{"code" : "20240716"}]},{"uri" : "https://www.cms.gov/Medicare/Coding/place-of-service-codes/Place_of_Service_Code_Set","version" : [{"code" : "20240502"}]},{"uri" : "https://www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/HospitalAcqCond/Coding","version" : [{"code" : "07/14/2020"}]},{"uri" : "https://www.humanservices.gov.au/organisations/health-professionals/enablers/air-vaccine-code-formats","version" : [{"code" : "20210222"}]},{"uri" : "https://www.iana.org/time-zones","version" : [{"code" : "20210124"}]},{"uri" : "https://www.usps.com/"},{"uri" : "urn:ietf:bcp:13"},{"uri" : "urn:ietf:bcp:47"},{"uri" : "urn:ietf:rfc:3986","version" : [{"code" : "n/a"}]},{"uri" : "urn:iso:std:iso:11073:10101","version" : [{"code" : "2024-12-05"}]},{"uri" : "urn:iso:std:iso:3166:-2","version" : [{"code" : "2021"}]},{"uri" : "urn:iso:std:iso:3166","version" : [{"code" : "2018"}]},{"uri" : "urn:iso:std:iso:3166","version" : [{"code" : "20210120"}]},{"uri" : "urn:iso:std:iso:4217"},{"uri" : "urn:iso-astm:E1762-95:2013","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1001.101.104.16592","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1005.17"},{"uri" : "urn:oid:2.16.840.1.113883.2.9.6.2.7","version" : [{"code" : "ISCO-08"}]},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8"},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8","version" : [{"code" : "5.0.0"}]}],"expansion" : {"parameter" : [{"name" : "cache-id","documentation" : "This server supports caching terminology resources between calls. Clients only need to send value sets and codesystems once; there after they are automatically in scope for calls with the same cache-id. The cache is retained for 30 min from last call"},{"name" : "tx-resource","documentation" : "Additional valuesets needed for evaluation e.g. value sets referred to from the import statement of the value set being expanded"},{"name" : "_incomplete"},{"name" : "abstract"},{"name" : "activeOnly"},{"name" : "check-system-version"},{"name" : "count"},{"name" : "default-to-latest-version"},{"name" : "displayLanguage"},{"name" : "excludeNested"},{"name" : "excludeNotForUI"},{"name" : "excludePostCoordinated"},{"name" : "force-system-version"},{"name" : "inactive"},{"name" : "includeAlternateCodes"},{"name" : "includeDefinition"},{"name" : "includeDesignations"},{"name" : "incomplete-ok"},{"name" : "limitedExpansion"},{"name" : "mode","documentation" : "=lenient-display-validation"},{"name" : "no-cache"},{"name" : "offset"},{"name" : "profile"},{"name" : "property"},{"name" : "system-version"},{"name" : "valueSetMode","documentation" : "= CHECK_MEMBERSHIP_ONLY | NO_MEMBERSHIP_CHECK"}]}}

#3

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 19 Dec 2025 22:11:51 GMT
last-modified:Fri, 19 Dec 2025 22:11:51 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#4

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-B*15:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 19 Dec 2025 22:11:51 GMT
last-modified:Fri, 19 Dec 2025 22:11:51 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-B*15:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*15:01:01G (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*15:01:01G\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#5

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 19 Dec 2025 22:11:52 GMT
last-modified:Fri, 19 Dec 2025 22:11:52 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#6

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:52 GMT
last-modified:Fri, 19 Dec 2025 22:11:52 GMT
pragma:no-cache
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x-request-id:252-942251

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#7

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:52 GMT
last-modified:Fri, 19 Dec 2025 22:11:52 GMT
pragma:no-cache
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x-request-id:252-942253

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#8

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30102-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:763
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:52 GMT
last-modified:Fri, 19 Dec 2025 22:11:52 GMT
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x-request-id:252-942254

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#9

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
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content-length:755
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:53 GMT
last-modified:Fri, 19 Dec 2025 22:11:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-942257

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#10

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:53 GMT
last-modified:Fri, 19 Dec 2025 22:11:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-942261

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#11

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:53 GMT
last-modified:Fri, 19 Dec 2025 22:11:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-942263

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#12

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:53 GMT
last-modified:Fri, 19 Dec 2025 22:11:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-942264

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#13

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:54 GMT
last-modified:Fri, 19 Dec 2025 22:11:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942266

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#14

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:54 GMT
last-modified:Fri, 19 Dec 2025 22:11:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942268

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#15

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:54 GMT
last-modified:Fri, 19 Dec 2025 22:11:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942269

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#16

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:54 GMT
last-modified:Fri, 19 Dec 2025 22:11:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942270

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#17

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:54 GMT
last-modified:Fri, 19 Dec 2025 22:11:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942272

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#18

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:54 GMT
last-modified:Fri, 19 Dec 2025 22:11:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942273

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#19

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:55 GMT
last-modified:Fri, 19 Dec 2025 22:11:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-942274

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#20

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:55 GMT
last-modified:Fri, 19 Dec 2025 22:11:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-942275

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#21

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:55 GMT
last-modified:Fri, 19 Dec 2025 22:11:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-942276

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#22

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:55 GMT
last-modified:Fri, 19 Dec 2025 22:11:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-942278

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#23

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:55 GMT
last-modified:Fri, 19 Dec 2025 22:11:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-942279

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#24

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:55 GMT
last-modified:Fri, 19 Dec 2025 22:11:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-942281

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#25

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942282

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#26

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942284

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#27

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942285

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#28

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942287

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#29

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942289

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#30

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942291

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#31

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:56 GMT
last-modified:Fri, 19 Dec 2025 22:11:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942293

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#32

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942294

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#33

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942296

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#34

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942297

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#35

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942299

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#36

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942302

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#37

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942303

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0    : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0    : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#38

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:57 GMT
last-modified:Fri, 19 Dec 2025 22:11:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942305

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#39

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942307

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#40

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942309

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#41

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942310

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#42

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942314

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#43

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942315

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#44

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942316

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#45

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942317

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#46

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:58 GMT
last-modified:Fri, 19 Dec 2025 22:11:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942318

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#47

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942319

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#48

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942323

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#49

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942324

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#50

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942326

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#51

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942328

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#52

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942330

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#53

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942331

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#54

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:11:59 GMT
last-modified:Fri, 19 Dec 2025 22:11:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942332

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#55

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942334

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#56

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942337

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#57

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942340

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#58

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942341

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#59

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942343

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#60

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942344

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#61

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:00 GMT
last-modified:Fri, 19 Dec 2025 22:12:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942346

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#62

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942347

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#63

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942350

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#64

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942352

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#65

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942353

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#66

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942356

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#67

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942358

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#68

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:01 GMT
last-modified:Fri, 19 Dec 2025 22:12:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-942359

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#69

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:02 GMT
last-modified:Fri, 19 Dec 2025 22:12:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942362

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#70

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:02 GMT
last-modified:Fri, 19 Dec 2025 22:12:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942364

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#71

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:02 GMT
last-modified:Fri, 19 Dec 2025 22:12:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942366

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#72

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:02 GMT
last-modified:Fri, 19 Dec 2025 22:12:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942368

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#73

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:02 GMT
last-modified:Fri, 19 Dec 2025 22:12:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942370

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#74

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:02 GMT
last-modified:Fri, 19 Dec 2025 22:12:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942371

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#75

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:03 GMT
last-modified:Fri, 19 Dec 2025 22:12:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942373

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#76

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:03 GMT
last-modified:Fri, 19 Dec 2025 22:12:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942375

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#77

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:03 GMT
last-modified:Fri, 19 Dec 2025 22:12:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942376

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0    : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0    : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#78

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:03 GMT
last-modified:Fri, 19 Dec 2025 22:12:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942378

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#79

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:03 GMT
last-modified:Fri, 19 Dec 2025 22:12:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942379

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#80

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:03 GMT
last-modified:Fri, 19 Dec 2025 22:12:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942380

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#81

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:04 GMT
last-modified:Fri, 19 Dec 2025 22:12:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-942381

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#82

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:04 GMT
last-modified:Fri, 19 Dec 2025 22:12:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-942383

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#83

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:757
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:04 GMT
last-modified:Fri, 19 Dec 2025 22:12:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-942384

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#84

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:745
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:05 GMT
last-modified:Fri, 19 Dec 2025 22:12:05 GMT
pragma:no-cache
server:nginx
x-request-id:252-942386

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#85

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"HLA-A*02:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1523
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:05 GMT
last-modified:Fri, 19 Dec 2025 22:12:05 GMT
pragma:no-cache
server:nginx
x-request-id:252-942388

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*02:01"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#86

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:752
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:06 GMT
last-modified:Fri, 19 Dec 2025 22:12:06 GMT
pragma:no-cache
server:nginx
x-request-id:252-942389

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#87

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:06 GMT
last-modified:Fri, 19 Dec 2025 22:12:06 GMT
pragma:no-cache
server:nginx
x-request-id:252-942391

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#88

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:765
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:07 GMT
last-modified:Fri, 19 Dec 2025 22:12:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-942394

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#89

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:07 GMT
last-modified:Fri, 19 Dec 2025 22:12:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-942399

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#90

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:07 GMT
last-modified:Fri, 19 Dec 2025 22:12:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-942400

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#91

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:08 GMT
last-modified:Fri, 19 Dec 2025 22:12:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-942402

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#92

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:757
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:08 GMT
last-modified:Fri, 19 Dec 2025 22:12:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-942403

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#93

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:08 GMT
last-modified:Fri, 19 Dec 2025 22:12:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-942405

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#94

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:09 GMT
last-modified:Fri, 19 Dec 2025 22:12:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-942406

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#95

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1572
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:09 GMT
last-modified:Fri, 19 Dec 2025 22:12:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-942408

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#96

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:750
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:10 GMT
last-modified:Fri, 19 Dec 2025 22:12:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-942409

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#97

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:10 GMT
last-modified:Fri, 19 Dec 2025 22:12:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-942411

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#98

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:756
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:10 GMT
last-modified:Fri, 19 Dec 2025 22:12:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-942412

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#99

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:11 GMT
last-modified:Fri, 19 Dec 2025 22:12:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-942415

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#100

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:746
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:11 GMT
last-modified:Fri, 19 Dec 2025 22:12:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-942416

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#101

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:12 GMT
last-modified:Fri, 19 Dec 2025 22:12:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-942419

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#102

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:12 GMT
last-modified:Fri, 19 Dec 2025 22:12:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-942424

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#103

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:764
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:13 GMT
last-modified:Fri, 19 Dec 2025 22:12:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-942427

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#104

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:13 GMT
last-modified:Fri, 19 Dec 2025 22:12:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-942432

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#105

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:744
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:14 GMT
last-modified:Fri, 19 Dec 2025 22:12:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-942435

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#106

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:15 GMT
last-modified:Fri, 19 Dec 2025 22:12:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-942441

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#107

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"%"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:15 GMT
last-modified:Fri, 19 Dec 2025 22:12:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-942445

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "%"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "%"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#% (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#%\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#108

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:749
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:15 GMT
last-modified:Fri, 19 Dec 2025 22:12:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-942447

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#109

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:16 GMT
last-modified:Fri, 19 Dec 2025 22:12:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-942449

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#1 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#1\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#110

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:16 GMT
last-modified:Fri, 19 Dec 2025 22:12:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-942451

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#111

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:17 GMT
last-modified:Fri, 19 Dec 2025 22:12:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-942452

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81301-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#112

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:17 GMT
last-modified:Fri, 19 Dec 2025 22:12:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-942453

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#113

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:776
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:18 GMT
last-modified:Fri, 19 Dec 2025 22:12:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-942455

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#114

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:751
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:19 GMT
last-modified:Fri, 19 Dec 2025 22:12:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-942457

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#115

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:19 GMT
last-modified:Fri, 19 Dec 2025 22:12:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-942458

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#116

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:19 GMT
last-modified:Fri, 19 Dec 2025 22:12:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-942459

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n15 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n15 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#117

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:19 GMT
last-modified:Fri, 19 Dec 2025 22:12:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-942460

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#118

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:20 GMT
last-modified:Fri, 19 Dec 2025 22:12:20 GMT
pragma:no-cache
server:nginx
x-request-id:252-942462

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#119

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:20 GMT
last-modified:Fri, 19 Dec 2025 22:12:20 GMT
pragma:no-cache
server:nginx
x-request-id:252-942463

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#120

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"HLA-A*02:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1523
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:20 GMT
last-modified:Fri, 19 Dec 2025 22:12:20 GMT
pragma:no-cache
server:nginx
x-request-id:252-942464

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*02:01"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#121

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:21 GMT
last-modified:Fri, 19 Dec 2025 22:12:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-942465

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#122

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51969-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:21 GMT
last-modified:Fri, 19 Dec 2025 22:12:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-942467

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#123

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"HLA-A*02:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1523
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:21 GMT
last-modified:Fri, 19 Dec 2025 22:12:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-942469

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*02:01"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#124

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:22 GMT
last-modified:Fri, 19 Dec 2025 22:12:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-942470

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#125

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:22 GMT
last-modified:Fri, 19 Dec 2025 22:12:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-942472

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#126

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1754
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:22 GMT
last-modified:Fri, 19 Dec 2025 22:12:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-942473

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "version","valueString" : "137"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP|137\"\r\n"}]}

#127

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81299-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:22 GMT
last-modified:Fri, 19 Dec 2025 22:12:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-942475

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81299-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#128

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81300-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:23 GMT
last-modified:Fri, 19 Dec 2025 22:12:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-942480

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81300-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#129

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:23 GMT
last-modified:Fri, 19 Dec 2025 22:12:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-942484

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#130

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:23 GMT
last-modified:Fri, 19 Dec 2025 22:12:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-942485

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#131

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"HLA-A*02:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1523
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:24 GMT
last-modified:Fri, 19 Dec 2025 22:12:24 GMT
pragma:no-cache
server:nginx
x-request-id:252-942487

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*02:01"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#132

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1/1000000"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:780
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:24 GMT
last-modified:Fri, 19 Dec 2025 22:12:24 GMT
pragma:no-cache
server:nginx
x-request-id:252-942489

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1/1000000"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1/1000000"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#1/1000000 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#1/1000000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#133

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:854
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:24 GMT
last-modified:Fri, 19 Dec 2025 22:12:24 GMT
pragma:no-cache
server:nginx
x-request-id:252-942494

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.32.0)\" (content = complete)\r\n"}]}

#134

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:24 GMT
last-modified:Fri, 19 Dec 2025 22:12:24 GMT
pragma:no-cache
server:nginx
x-request-id:252-942497

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#135

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:25 GMT
last-modified:Fri, 19 Dec 2025 22:12:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-942499

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#136

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:25 GMT
last-modified:Fri, 19 Dec 2025 22:12:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-942502

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#137

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:25 GMT
last-modified:Fri, 19 Dec 2025 22:12:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-942504

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#138

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:25 GMT
last-modified:Fri, 19 Dec 2025 22:12:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-942506

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#139

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:836
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:26 GMT
last-modified:Fri, 19 Dec 2025 22:12:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-942509

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#140

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:828
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:26 GMT
last-modified:Fri, 19 Dec 2025 22:12:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-942513

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#141

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:26 GMT
last-modified:Fri, 19 Dec 2025 22:12:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-942515

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#142

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:27 GMT
last-modified:Fri, 19 Dec 2025 22:12:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-942517

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#143

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:27 GMT
last-modified:Fri, 19 Dec 2025 22:12:27 GMT
pragma:no-cache
server:nginx
x-request-id:252-942519

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#144

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:27 GMT
last-modified:Fri, 19 Dec 2025 22:12:27 GMT
pragma:no-cache
server:nginx
x-request-id:252-942522

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#145

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1560
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:28 GMT
last-modified:Fri, 19 Dec 2025 22:12:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-942527

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#146

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:28 GMT
last-modified:Fri, 19 Dec 2025 22:12:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-942529

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#147

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1563
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:28 GMT
last-modified:Fri, 19 Dec 2025 22:12:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-942531

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#148

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:28 GMT
last-modified:Fri, 19 Dec 2025 22:12:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-942533

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#149

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:28 GMT
last-modified:Fri, 19 Dec 2025 22:12:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-942537

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#150

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1703
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:29 GMT
last-modified:Fri, 19 Dec 2025 22:12:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-942540

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#151

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1741
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:29 GMT
last-modified:Fri, 19 Dec 2025 22:12:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-942541

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}

#152

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1642
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:29 GMT
last-modified:Fri, 19 Dec 2025 22:12:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-942544

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#153

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:29 GMT
last-modified:Fri, 19 Dec 2025 22:12:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-942547

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#154

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:29 GMT
last-modified:Fri, 19 Dec 2025 22:12:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-942549

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#155

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:30 GMT
last-modified:Fri, 19 Dec 2025 22:12:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-942552

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48000-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#156

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:30 GMT
last-modified:Fri, 19 Dec 2025 22:12:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-942557

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000003.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#157

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:30 GMT
last-modified:Fri, 19 Dec 2025 22:12:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-942558

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#158

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:31 GMT
last-modified:Fri, 19 Dec 2025 22:12:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-942562

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#159

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:31 GMT
last-modified:Fri, 19 Dec 2025 22:12:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-942564

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#160

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:31 GMT
last-modified:Fri, 19 Dec 2025 22:12:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-942566

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#161

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:31 GMT
last-modified:Fri, 19 Dec 2025 22:12:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-942568

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#162

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:763
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:32 GMT
last-modified:Fri, 19 Dec 2025 22:12:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-942570

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#163

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:772
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:32 GMT
last-modified:Fri, 19 Dec 2025 22:12:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-942576

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94186-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#164

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:761
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:33 GMT
last-modified:Fri, 19 Dec 2025 22:12:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-942581

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82309-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#165

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:33 GMT
last-modified:Fri, 19 Dec 2025 22:12:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-942585

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#166

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:33 GMT
last-modified:Fri, 19 Dec 2025 22:12:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-942586

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#167

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:33 GMT
last-modified:Fri, 19 Dec 2025 22:12:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-942590

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#168

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:33 GMT
last-modified:Fri, 19 Dec 2025 22:12:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-942591

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#169

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:34 GMT
last-modified:Fri, 19 Dec 2025 22:12:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-942594

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#170

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1483
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:34 GMT
last-modified:Fri, 19 Dec 2025 22:12:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-942595

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX,t(9;22)(q34;q4)"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[https://iscn.karger.com#46,XX,t(9;22)(q34;q4) (\"\")]\"\r\n0 0     : 0ms  : Check \"https://iscn.karger.com#46,XX,t(9;22)(q34;q4)\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#171

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1435
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:34 GMT
last-modified:Fri, 19 Dec 2025 22:12:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-942598

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[https://iscn.karger.com#46,XX (\"\")]\"\r\n0 0     : 0ms  : Check \"https://iscn.karger.com#46,XX\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#172

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:34 GMT
last-modified:Fri, 19 Dec 2025 22:12:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-942600

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#173

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:34 GMT
last-modified:Fri, 19 Dec 2025 22:12:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-942601

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#174

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:35 GMT
last-modified:Fri, 19 Dec 2025 22:12:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-942602

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#175

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:35 GMT
last-modified:Fri, 19 Dec 2025 22:12:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-942603

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#176

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:35 GMT
last-modified:Fri, 19 Dec 2025 22:12:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-942605

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000009.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#177

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:35 GMT
last-modified:Fri, 19 Dec 2025 22:12:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-942606

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#178

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:36 GMT
last-modified:Fri, 19 Dec 2025 22:12:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-942609

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#179

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:36 GMT
last-modified:Fri, 19 Dec 2025 22:12:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-942610

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#180

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:36 GMT
last-modified:Fri, 19 Dec 2025 22:12:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-942612

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#181

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:37 GMT
last-modified:Fri, 19 Dec 2025 22:12:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-942613

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#182

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:37 GMT
last-modified:Fri, 19 Dec 2025 22:12:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-942615

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#183

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:37 GMT
last-modified:Fri, 19 Dec 2025 22:12:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-942616

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#184

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:37 GMT
last-modified:Fri, 19 Dec 2025 22:12:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-942617

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#185

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:37 GMT
last-modified:Fri, 19 Dec 2025 22:12:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-942618

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#186

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:38 GMT
last-modified:Fri, 19 Dec 2025 22:12:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-942619

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#187

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:38 GMT
last-modified:Fri, 19 Dec 2025 22:12:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-942621

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000023.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#188

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:38 GMT
last-modified:Fri, 19 Dec 2025 22:12:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-942622

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#189

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:744
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:39 GMT
last-modified:Fri, 19 Dec 2025 22:12:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-942623

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#190

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:39 GMT
last-modified:Fri, 19 Dec 2025 22:12:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-942625

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000017.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#191

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30100-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:39 GMT
last-modified:Fri, 19 Dec 2025 22:12:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-942626

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#192

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:40 GMT
last-modified:Fri, 19 Dec 2025 22:12:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-942627

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#193

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:40 GMT
last-modified:Fri, 19 Dec 2025 22:12:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-942628

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#194

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:40 GMT
last-modified:Fri, 19 Dec 2025 22:12:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-942629

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#195

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:40 GMT
last-modified:Fri, 19 Dec 2025 22:12:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-942630

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#196

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1530
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:40 GMT
last-modified:Fri, 19 Dec 2025 22:12:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-942631

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000016.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#197

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:41 GMT
last-modified:Fri, 19 Dec 2025 22:12:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-942632

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#198

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:41 GMT
last-modified:Fri, 19 Dec 2025 22:12:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-942633

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#199

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:41 GMT
last-modified:Fri, 19 Dec 2025 22:12:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-942634

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#200

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:41 GMT
last-modified:Fri, 19 Dec 2025 22:12:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-942635

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#201

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1642
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:41 GMT
last-modified:Fri, 19 Dec 2025 22:12:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-942637

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#202

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA26421-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:768
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:43 GMT
last-modified:Fri, 19 Dec 2025 22:12:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-942639

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26421-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#203

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:700
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:43 GMT
server:nginx
x-request-id:252-942642

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded"}}]}

#204

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:700
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:43 GMT
server:nginx
x-request-id:252-942644

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded"}}]}

#205

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1510
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:43 GMT
last-modified:Fri, 19 Dec 2025 22:12:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-942645

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:0002072\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#206

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1510
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:44 GMT
last-modified:Fri, 19 Dec 2025 22:12:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-942646

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#207

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2003
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:44 GMT
last-modified:Fri, 19 Dec 2025 22:12:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-942647

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:c5735aaa-79c1-45e6-af53-dbe0093d4dfa","timestamp" : "2025-12-19T22:12:44.176Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}

#208

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:737
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:44 GMT
last-modified:Fri, 19 Dec 2025 22:12:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-942648

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:00289afc-ed76-48f5-a28e-9e1e1e57a6e4","timestamp" : "2025-12-19T22:12:44.410Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}

#209

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://loinc.org","concept":[{"code":"85337-4","display":"Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"},{"code":"77637-7","display":"HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"},{"code":"40557-1","display":"Progesterone receptor Ag [Presence] in Tissue by Immune stain"},{"code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"code":"59025-7","display":"Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"},{"code":"59003-4","display":"Lactoferrin Ab [Units/volume] in Serum by Immunoassay"},{"code":"10495-0","display":"Insulin Ag [Presence] in Tissue by Immune stain"},{"code":"16550-6","display":"Carbohydrates [Identifier] in Urine"},{"code":"2569-2","display":"Lipids [Mass/volume] in Serum"},{"code":"4551-8","display":"Hemoglobin A2/Hemoglobin.total in Blood"},{"code":"19195-7","display":"Prostate specific Ag [Units/volume] in Serum or Plasma"},{"code":"64083-9","display":"MGMT gene methylation score in Tissue by Molecular genetics method"},{"code":"62862-8","display":"Microsatellite instability [Presence] in Tissue by Immune stain"},{"code":"81704-9","display":"Microsatellite instability marker D17S250 in Cancer specimen Qualitative"},{"code":"94077-5","display":"Tumor mutation burden [Interpretation]"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2345
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:44 GMT
last-modified:Fri, 19 Dec 2025 22:12:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-942649

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:dd941134-5269-4c2f-ac67-c4ad603cf98e","timestamp" : "2025-12-19T22:12:44.489Z","total" : 16,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "85337-4","display" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"system" : "http://loinc.org","code" : "77637-7","display" : "HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"},{"system" : "http://loinc.org","code" : "40557-1","display" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"system" : "http://loinc.org","code" : "59025-7","display" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"},{"system" : "http://loinc.org","code" : "59003-4","display" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"},{"system" : "http://loinc.org","code" : "10495-0","display" : "Insulin Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "16550-6","display" : "Carbohydrates [Identifier] in Urine"},{"system" : "http://loinc.org","code" : "2569-2","display" : "Lipids [Mass/volume] in Serum"},{"system" : "http://loinc.org","code" : "4551-8","display" : "Hemoglobin A2/Hemoglobin.total in Blood"},{"system" : "http://loinc.org","code" : "19195-7","display" : "Prostate specific Ag [Units/volume] in Serum or Plasma"},{"system" : "http://loinc.org","code" : "64083-9","display" : "MGMT gene methylation score in Tissue by Molecular genetics method"},{"system" : "http://loinc.org","code" : "62862-8","display" : "Microsatellite instability [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "81704-9","display" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"},{"system" : "http://loinc.org","code" : "94077-5","display" : "Tumor mutation burden [Interpretation]"}]}}

#210

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C120465","display":"Homologous Recombination Repair Deficiency"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:44 GMT
server:nginx
x-request-id:252-942651

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#211

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-biomarker-code-vs-inc-1","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C120465","display":"Homologous Recombination Repair Deficiency"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:627
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:44 GMT
server:nginx
x-request-id:252-942654

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}

#212

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1510
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:45 GMT
last-modified:Fri, 19 Dec 2025 22:12:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-942655

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:0001537\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#213

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"jurisdiction","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"vocab"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"deprecated"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/jurisdiction","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.48"}],"version":"6.0.0-ballot3","name":"JurisdictionValueSet","title":"Jurisdiction ValueSet","status":"draft","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International / Terminology Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]},{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/Vocab"}]}],"description":"This value set defines a base set of codes for country, country subdivision and region    for indicating where a resource is intended to be used.   \r\n   \r\n   Note: The codes for countries and country subdivisions are taken from    [ISO 3166](https://www.iso.org/iso-3166-country-codes.html)    while the codes for \"supra-national\" regions are from    [UN Standard country or area codes for statistical use (M49)](http://unstats.un.org/unsd/methods/m49/m49.htm).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:iso:std:iso:3166"},{"system":"urn:iso:std:iso:3166:-2"},{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","filter":[{"property":"class","op":"=","value":"region"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2193
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:45 GMT
last-modified:Fri, 19 Dec 2025 22:12:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-942656

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unstats.un.org/unsd/methods/m49/m49.htm"},{"name" : "code","valueCode" : "001"},{"name" : "display","valueString" : "World"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm","code" : "001","display" : "World"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "MSG_DEPRECATED"}],"severity" : "information","code" : "business-rule","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "status-check"}],"text" : "Reference to deprecated ValueSet http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(urn:iso:std:iso:3166)\"\r\n15 0    : 0ms  : CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n15 0    : 0ms  : Prepare include: \"(urn:iso:std:iso:3166:-2)\"\r\n15 0    : 0ms  : CodeSystem found: \"urn:iso:std:iso:3166:-2|2021 (from fhir.tx.support.r4#0.32.0)\"\r\n15 0    : 0ms  : Prepare include: \"(http://unstats.un.org/unsd/methods/m49/m49.htm)(class=region)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://unstats.un.org/unsd/methods/m49/m49.htm|\"\r\n15 0    : 0ms  : Validate \"[http://unstats.un.org/unsd/methods/m49/m49.htm#001 (\"World\")]\"\r\n15 0    : 0ms  : Check \"http://unstats.un.org/unsd/methods/m49/m49.htm#001\"\r\n15 0    : 0ms  : CodeSystem found: http://unstats.un.org/unsd/methods/m49/m49.htm| for http://unstats.un.org/unsd/methods/m49/m49.htm\r\n15 0    : 0ms  : check code in (http://unstats.un.org/unsd/methods/m49/m49.htm)(class=region) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Filter \"class=region\": Code \"001\" found in http://unstats.un.org/unsd/methods/m49/m49.htm|\r\n"}]}

#214

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fhuman-phenotype-ontology.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:251
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-942658

{"resourceType" : "Bundle","id" : "67b82930-2757-4c13-bf08-6be5c71402","meta" : {"lastUpdated" : "2025-12-19T22:12:45.660Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://human-phenotype-ontology.org"}]}

#215

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fwww.sequenceontology.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:247
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-942659

{"resourceType" : "Bundle","id" : "216626de-38f4-40a8-8541-2b5a2af2c5","meta" : {"lastUpdated" : "2025-12-19T22:12:45.863Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://www.sequenceontology.org"}]}

#216

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:46 GMT
last-modified:Fri, 19 Dec 2025 22:12:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-942660

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:0002072\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#217

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:46 GMT
last-modified:Fri, 19 Dec 2025 22:12:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-942661

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#218

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Floinc.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:232
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-942662

{"resourceType" : "Bundle","id" : "03e05b0e-adc6-4737-b569-8aa53692a2","meta" : {"lastUpdated" : "2025-12-19T22:12:46.379Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://loinc.org"}]}

#219

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10315-2","display":"Ultrarapid metabolizer"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:802
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:46 GMT
last-modified:Fri, 19 Dec 2025 22:12:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-942663

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10315-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Ultrarapid metabolizer"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest, display-warning\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA10315-2 (\"Ultrarapid metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA10315-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#220

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10317-8","display":"Intermediate metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19542-2","display":"Low Risk"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19541-4","display":"High Risk"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9660-7","display":"Presumed resistant"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9661-5","display":"Presumed responsive"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6682-4","display":"Unknown Significance"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6675-8","display":"Benign"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6674-1","display":"Presumed Benign"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9662-3","display":"Presumed non-responsive"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25392-4","display":"Increased function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25393-2","display":"Normal function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25395-7","display":"Decreased function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25394-0","display":"Poor function"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:5840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:46 GMT
last-modified:Fri, 19 Dec 2025 22:12:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-942664

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10317-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Intermediate metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9660-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9661-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6682-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Unknown Significance"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6675-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6674-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9662-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed non-responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25392-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25393-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25395-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Decreased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25394-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor function"}]}}]}

#221

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fsnomed.info%2Fsct HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:238
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-942666

{"resourceType" : "Bundle","id" : "4cf6a4ce-8e89-463d-945c-598f5890c7","meta" : {"lastUpdated" : "2025-12-19T22:12:46.879Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://snomed.info/sct"}]}

#222

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1016
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:47 GMT
last-modified:Fri, 19 Dec 2025 22:12:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-942667

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest, display-warning\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial (finding)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#444734003\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#223

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial (finding)"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:459
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:47 GMT
last-modified:Fri, 19 Dec 2025 22:12:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-942668

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"}]}}]}

#224

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fwww.genenames.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:240
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-942669

{"resourceType" : "Bundle","id" : "860dd175-896e-4773-92c6-5e4c1f7001","meta" : {"lastUpdated" : "2025-12-19T22:12:47.473Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://www.genenames.org"}]}

#225

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fwww.genenames.org%2Fgenegroup HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:250
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-942670

{"resourceType" : "Bundle","id" : "1e4ca1bc-0b11-461b-9d14-e7e18cc652","meta" : {"lastUpdated" : "2025-12-19T22:12:47.676Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://www.genenames.org/genegroup"}]}

#226

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fvarnomen.hgvs.org HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:240
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-942672

{"resourceType" : "Bundle","id" : "3193466c-26ff-4905-8c9b-2217990b55","meta" : {"lastUpdated" : "2025-12-19T22:12:47.910Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://varnomen.hgvs.org"}]}

#227

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85337-4","display":"Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:48 GMT
last-modified:Fri, 19 Dec 2025 22:12:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-942673

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85337-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest, display-warning\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#85337-4 (\"Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#85337-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#228

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"77637-7","display":"HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"40557-1","display":"Progesterone receptor Ag [Presence] in Tissue by Immune stain"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"59025-7","display":"Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"59003-4","display":"Lactoferrin Ab [Units/volume] in Serum by Immunoassay"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"10495-0","display":"Insulin Ag [Presence] in Tissue by Immune stain"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"16550-6","display":"Carbohydrates [Identifier] in Urine"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"2569-2","display":"Lipids [Mass/volume] in Serum"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"4551-8","display":"Hemoglobin A2/Hemoglobin.total in Blood"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"19195-7","display":"Prostate specific Ag [Units/volume] in Serum or Plasma"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"64083-9","display":"MGMT gene methylation score in Tissue by Molecular genetics method"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62862-8","display":"Microsatellite instability [Presence] in Tissue by Immune stain"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81704-9","display":"Microsatellite instability marker D17S250 in Cancer specimen Qualitative"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94077-5","display":"Tumor mutation burden 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200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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date:Fri, 19 Dec 2025 22:12:48 GMT
last-modified:Fri, 19 Dec 2025 22:12:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-942674

{"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "72382-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "77637-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "40557-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "59025-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "59003-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "10495-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Insulin Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "16550-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Carbohydrates [Identifier] in Urine"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "2569-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Lipids [Mass/volume] in Serum"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "4551-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Hemoglobin A2/Hemoglobin.total in Blood"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "19195-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Prostate specific Ag [Units/volume] in Serum or Plasma"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "64083-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MGMT gene methylation score in Tissue by Molecular genetics method"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62862-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81704-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94077-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Tumor mutation burden [Interpretation]"}]}}]}

#229

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:266
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-942675

{"resourceType" : "Bundle","id" : "af9f198e-ff31-45b6-9241-de9426ca66","meta" : {"lastUpdated" : "2025-12-19T22:12:48.364Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"}]}

#230

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C120465","display":"Homologous Recombination Repair Deficiency"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"lenient-display-validation","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"mode","valueString":"lenient-display-validation"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1787
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:48 GMT
last-modified:Fri, 19 Dec 2025 22:12:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-942676

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C120465"},{"name" : "message","valueString" : "Unknown Code 'C120465' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C120465' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest, display-warning\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120465 (\"Homologous Recombination Repair Deficiency\")]\"\r\n0 0     : 0ms  : Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120465\"\r\n0 0     : 0ms  : Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.32.0)\" (content = fragment)\r\n"}]}

#231

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1506
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:48 GMT
last-modified:Fri, 19 Dec 2025 22:12:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-942677

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:0001537\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#232

POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9658-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, 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#233

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#234

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#235

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#236

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"5792-7"}},{"name":"valueset-membership-only","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4034-6"}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "5792-7"},{"name" : "message","valueString" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4034-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, membership-only, default-to-latest\r\n0 0     : 0ms  : Validate \"[http://loinc.org#5792-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#5792-7\"\r\n"}]}

#237

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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cache-control:public, max-age=600
connection:keep-alive
content-length:868
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:53 GMT
last-modified:Fri, 19 Dec 2025 22:12:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-942687

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#238

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:884
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:53 GMT
last-modified:Fri, 19 Dec 2025 22:12:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-942689

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#239

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:54 GMT
last-modified:Fri, 19 Dec 2025 22:12:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942690

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#240

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48000-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:922
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:54 GMT
last-modified:Fri, 19 Dec 2025 22:12:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-942692

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48000-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48000-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#241

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:56 GMT
last-modified:Fri, 19 Dec 2025 22:12:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942694

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#242

GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fdicom.nema.org%2Fmedical%2Fdicom%2Fcurrent%2Foutput%2Fchtml%2Fpart16%2Fsect_CID_33.html HTTP/1.0
User-Agent: hapi-fhir-tooling-client
Accept: application/fhir+json

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4699
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-942696

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#243

GET https://tx.fhir.org/r5/ValueSet/dicom-cid-33-Modality HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4308
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-942697

{"resourceType" : "ValueSet","id" : "dicom-cid-33-Modality","url" : "http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:1.2.840.10008.6.1.1283"}],"version" : "2025.3.20250714","name" : "Modality","status" : "active","experimental" : false,"date" : "2025-07-14","publisher" : "NEMA MITA DICOM","description" : "Transitive closure of CID 33 Modality","copyright" : "© 2025 NEMA","compose" : {"include" : [{"system" : "http://dicom.nema.org/resources/ontology/DCM","concept" : [{"code" : "BMD","display" : "Bone Mineral Densitometry"},{"code" : "SM","display" : "Slide Microscopy"},{"code" : "EOG","display" : "Electrooculography"},{"code" : "SR","display" : "Structured Report Document"},{"code" : "FID","display" : "Spatial Fiducials"},{"code" : "OP","display" : "Ophthalmic Photography"},{"code" : "OT","display" : "Other Modality"},{"code" : "KO","display" : "Key Object Selection"},{"code" : "GM","display" : "General Microscopy"},{"code" : "ECG","display" : "Electrocardiography"},{"code" : "XA","display" : "X-Ray Angiography"},{"code" : "IOL","display" : "Intraocular Lens Calculation"},{"code" : "XC","display" : "External-camera Photography"},{"code" : "ASMT","display" : "Content Assessment Result"},{"code" : "DMS","display" : "Dermoscopy"},{"code" : "IVUS","display" : "Intravascular Ultrasound"},{"code" : "CR","display" : "Computed Radiography"},{"code" : "CT","display" : "Computed Tomography"},{"code" : "PA","display" : "Photoacoustic"},{"code" : "OSS","display" : "Optical Surface Scanner"},{"code" : "TG","display" : "Thermography"},{"code" : "REG","display" : "Registration"},{"code" : "LEN","display" : "Lensometry"},{"code" : "TEXTUREMAP","display" : "Texture Map"},{"code" : "RTDOSE","display" : "RT Dose"},{"code" : "OPTENF","display" : "Ophthalmic Tomography En Face"},{"code" : "HC","display" : "Hard Copy"},{"code" : "RTPLAN","display" : "RT Plan"},{"code" : "HD","display" : "Hemodynamic"},{"code" : "OCT","display" : "Optical Coherence Tomography"},{"code" : "BDUS","display" : "Ultrasound Bone Densitometry"},{"code" : "M3D","display" : "3D Manufacturing Modeling System"},{"code" : "DG","display" : "Diaphanography"},{"code" : "PR","display" : "Presentation State"},{"code" : "PT","display" : "Positron emission tomography"},{"code" : "LS","display" : "Laser surface scan"},{"code" : "EPS","display" : "Cardiac Electrophysiology"},{"code" : "PX","display" : "Panoramic X-Ray"},{"code" : "OPM","display" : "Ophthalmic Mapping"},{"code" : "OPTBSV","display" : "Ophthalmic Tomography B-scan Volume Analysis"},{"code" : "OPV","display" : "Ophthalmic Visual Field"},{"code" : "DX","display" : "Digital Radiography"},{"code" : "OPT","display" : "Ophthalmic Tomography"},{"code" : "DOC","display" : "Document"},{"code" : "RTRECORD","display" : "RT Treatment Record"},{"code" : "MG","display" : "Mammography"},{"code" : "US","display" : "Ultrasound"},{"code" : "IVOCT","display" : "Intravascular Optical Coherence Tomography"},{"code" : "EMG","display" : "Electromyography"},{"code" : "RTSTRUCT","display" : "RT Structure Set"},{"code" : "MR","display" : "Magnetic Resonance"},{"code" : "IO","display" : "Intra-oral Radiography"},{"code" : "EEG","display" : "Electroencephalography"},{"code" : "RTIMAGE","display" : "RT Image"},{"code" : "VA","display" : "Visual Acuity"},{"code" : "RESP","display" : "Respiratory"},{"code" : "ES","display" : "Endoscopy"},{"code" : "RWV","display" : "Real World Value Map"},{"code" : "AR","display" : "Autorefraction"},{"code" : "POS","display" : "Position Sensor"},{"code" : "SEG","display" : "Segmentation"},{"code" : "RG","display" : "Radiographic imaging"},{"code" : "RF","display" : "Radiofluoroscopy"},{"code" : "AU","display" : "Audio"},{"code" : "KER","display" : "Keratometry"},{"code" : "SMR","display" : "Stereometric Relationship"},{"code" : "CTPROTOCOL","display" : "CT Protocol"},{"code" : "STAIN","display" : "Automated Slide Stainer"},{"code" : "OAM","display" : "Ophthalmic Axial Measurements"},{"code" : "NM","display" : "Nuclear Medicine"},{"code" : "PLAN","display" : "Plan"},{"code" : "BI","display" : "Biomagnetic Imaging"},{"code" : "SRF","display" : "Subjective Refraction"},{"code" : "CFM","display" : "Confocal Microscopy"}]}]}}

#244

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:58 GMT
last-modified:Fri, 19 Dec 2025 22:12:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-942699

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#245

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:872
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:12:59 GMT
last-modified:Fri, 19 Dec 2025 22:12:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-942701

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#246

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:865
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:00 GMT
last-modified:Fri, 19 Dec 2025 22:13:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-942703

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#247

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:02 GMT
last-modified:Fri, 19 Dec 2025 22:13:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-942706

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#248

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:885
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:03 GMT
last-modified:Fri, 19 Dec 2025 22:13:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-942709

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#249

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:876
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:04 GMT
last-modified:Fri, 19 Dec 2025 22:13:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-942714

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#250

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:04 GMT
last-modified:Fri, 19 Dec 2025 22:13:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-942721

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#251

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:06 GMT
last-modified:Fri, 19 Dec 2025 22:13:06 GMT
pragma:no-cache
server:nginx
x-request-id:252-942729

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#252

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:877
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:07 GMT
last-modified:Fri, 19 Dec 2025 22:13:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-942730

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#253

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:877
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:08 GMT
last-modified:Fri, 19 Dec 2025 22:13:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-942732

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#254

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:863
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:08 GMT
last-modified:Fri, 19 Dec 2025 22:13:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-942734

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#81291-7\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#255

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:882
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:09 GMT
last-modified:Fri, 19 Dec 2025 22:13:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-942736

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#256

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:10 GMT
last-modified:Fri, 19 Dec 2025 22:13:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-942738

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#257

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:10 GMT
last-modified:Fri, 19 Dec 2025 22:13:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-942740

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#81302-2\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#258

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81301-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:11 GMT
last-modified:Fri, 19 Dec 2025 22:13:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-942741

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81301-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81301-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#259

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:883
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:12 GMT
last-modified:Fri, 19 Dec 2025 22:13:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-942743

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#260

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:12 GMT
last-modified:Fri, 19 Dec 2025 22:13:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-942744

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#261

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:874
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:13 GMT
last-modified:Fri, 19 Dec 2025 22:13:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-942747

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#262

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:866
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:13 GMT
last-modified:Fri, 19 Dec 2025 22:13:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-942752

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#263

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:14 GMT
last-modified:Fri, 19 Dec 2025 22:13:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-942758

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#264

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:15 GMT
last-modified:Fri, 19 Dec 2025 22:13:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-942763

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#265

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:869
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:15 GMT
last-modified:Fri, 19 Dec 2025 22:13:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-942768

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#266

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:16 GMT
last-modified:Fri, 19 Dec 2025 22:13:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-942774

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#53034-5\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#267

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94186-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:16 GMT
last-modified:Fri, 19 Dec 2025 22:13:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-942778

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94186-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94186-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#268

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82309-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:881
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:17 GMT
last-modified:Fri, 19 Dec 2025 22:13:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-942782

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82309-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82309-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#269

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:17 GMT
last-modified:Fri, 19 Dec 2025 22:13:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-942787

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#270

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:13:18 GMT
last-modified:Fri, 19 Dec 2025 22:13:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-942790

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#271

GET https://tx.fhir.org/r5/metadata HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:4378
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943030

{"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20251208221453.000Z. Server version 4.0.7 built 20251208221453.000Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>subsumes: see OperationDefinition/fso-subsumes</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.8.0"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-4.0.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-12-19T22:14:10.801Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "4.0.7","releaseDate" : "2025-12-08T22:14:53.000Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "subsumes","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-subsumes"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}

#272

GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
User-Agent: fhir/publisher

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:134307
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943031

{"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r5/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2025-12-19T22:14:10.894Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "5.0.0"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/account-aggregate","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-balance-term","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-billing-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-function","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-precheck-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-reason-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-relationship-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-required-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-selection-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/address-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/address-use","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/administrable-dose-form","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/administrative-gender","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/adverse-event-actuality","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-category","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-criticality","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/animal-tissue-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/appointmentstatus","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifactassessment-disposition","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifactassessment-information-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifactassessment-workflow-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifact-contribution-instance-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifact-contribution-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifact-url-classifier","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-direction-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-manual-completion-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-operator-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-response-code-types","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/asset-availability","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/audit-event-action","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/audit-event-severity","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/binding-strength","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderived-productcodes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderivedproductdispense-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderived-product-property-type-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderived-product-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/bundle-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/capability-statement-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/care-team-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/catalogType","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/certainty-rating","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/certainty-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/characteristic-combination","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/characteristic-offset","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/chargeitem-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-artifact-classifier","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-classification-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-status-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-summary-style","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-abstract-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-classification-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-part-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-status-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-medium","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/claim-decision","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/claim-decision-reason","version" : [{"code" : "5.0.0"}]},{"uri" : 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{"resourceType" : "Bundle","id" : "f81a9b1f-4cae-44a4-89d2-16a231f481","meta" : {"lastUpdated" : "2025-12-19T22:14:43.644Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://hl7.org/fhir/ValueSet/security-label-event-examples&version=6.0.0-ballot3"}]}

#276

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122555007","display":"Venous blood specimen"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1075
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:45 GMT
last-modified:Fri, 19 Dec 2025 22:14:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943137

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122555007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Venous blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122555007","display" : "Venous blood specimen"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#122555007 (\"Venous blood specimen\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#122555007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#277

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13303-3","display":"HLA-A+B+C (class I) [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:46 GMT
last-modified:Fri, 19 Dec 2025 22:14:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943138

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13303-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A+B+C (class I) [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13303-3","display" : "HLA-A+B+C (class I) [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#13303-3 (\"HLA-A+B+C (class I) [Type]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#13303-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#278

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:46 GMT
last-modified:Fri, 19 Dec 2025 22:14:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943143

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"Haplotype name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#279

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:01:01G","display":"HLA-A*01:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1738
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:46 GMT
last-modified:Fri, 19 Dec 2025 22:14:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943146

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:01:01G (\"HLA-A*01:01:01G\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#280

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:47 GMT
last-modified:Fri, 19 Dec 2025 22:14:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943148

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"Gene studied [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#281

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1459
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:47 GMT
last-modified:Fri, 19 Dec 2025 22:14:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943152

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n0 0     : 0ms  : Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}

#282

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:02","display":"HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1722
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:47 GMT
last-modified:Fri, 19 Dec 2025 22:14:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943154

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:02"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02 (\"HLA-A*01:02\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#283

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:929
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:48 GMT
last-modified:Fri, 19 Dec 2025 22:14:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-943156

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"Genotype display name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#284

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1679
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:48 GMT
last-modified:Fri, 19 Dec 2025 22:14:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-943160

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#285

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-B*15:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-B*15:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*15:01:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*15:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#286

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-B*57:01:01G","display":"HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-B*57:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G (\"HLA-B*57:01:01G\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}

#287

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#288

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-C*01:02:01G","display":"HLA-C*01:02:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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#289

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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#290

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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#291

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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server:nginx
x-request-id:252-943168

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#292

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6","display":"Genetic variant assessment"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:51 GMT
last-modified:Fri, 19 Dec 2025 22:14:51 GMT
pragma:no-cache
server:nginx
x-request-id:252-943174

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6","display" : "Genetic variant assessment"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"Genetic variant assessment\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#293

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:51 GMT
last-modified:Fri, 19 Dec 2025 22:14:51 GMT
pragma:no-cache
server:nginx
x-request-id:252-943178

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#294

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4","display":"Human reference sequence assembly version"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:52 GMT
last-modified:Fri, 19 Dec 2025 22:14:52 GMT
pragma:no-cache
server:nginx
x-request-id:252-943180

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4","display" : "Human reference sequence assembly version"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"Human reference sequence assembly version\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#295

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:52 GMT
last-modified:Fri, 19 Dec 2025 22:14:52 GMT
pragma:no-cache
server:nginx
x-request-id:252-943182

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14029-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#296

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:955
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:53 GMT
last-modified:Fri, 19 Dec 2025 22:14:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943184

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence ID\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#297

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1533
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:53 GMT
last-modified:Fri, 19 Dec 2025 22:14:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943188

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}

#298

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic state"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:905
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:54 GMT
last-modified:Fri, 19 Dec 2025 22:14:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943189

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic state"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"Allelic state\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#299

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:906
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:54 GMT
last-modified:Fri, 19 Dec 2025 22:14:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943192

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#300

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Ref nucleotide"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:55 GMT
last-modified:Fri, 19 Dec 2025 22:14:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-943195

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Ref nucleotide"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"Ref nucleotide\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#301

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Alt allele"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:909
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:55 GMT
last-modified:Fri, 19 Dec 2025 22:14:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-943199

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Alt allele"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"Alt allele\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#302

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6","display":"Genomic coord system"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:938
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:56 GMT
last-modified:Fri, 19 Dec 2025 22:14:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-943204

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6","display" : "Genomic coord system"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"Genomic coord system\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#303

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:885
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:56 GMT
last-modified:Fri, 19 Dec 2025 22:14:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-943206

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#304

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1170
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:57 GMT
last-modified:Fri, 19 Dec 2025 22:14:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943209

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}

#305

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1172
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:57 GMT
last-modified:Fri, 19 Dec 2025 22:14:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943211

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1040-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1040-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14029-5\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1040-6) at CodeableConcept.coding[0]\r\n15 15   : 15ms : Filter \"LIST=LL1040-6\": Code \"LA14029-5\" found in http://loinc.org|2.81\r\n"}]}

#306

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1181
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:57 GMT
last-modified:Fri, 19 Dec 2025 22:14:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943213

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL381-5 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL381-5)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL381-5) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}

#307

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1165
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:57 GMT
last-modified:Fri, 19 Dec 2025 22:14:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943214

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}

#308

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:58 GMT
last-modified:Fri, 19 Dec 2025 22:14:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-943216

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6705-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#309

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1175
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:14:58 GMT
last-modified:Fri, 19 Dec 2025 22:14:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-943220

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL381-5 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL381-5)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6705-3\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL381-5) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL381-5\": Code \"LA6705-3\" found in http://loinc.org|2.81\r\n"}]}

#310

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7","display":"Allelic phase"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:905
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:00 GMT
last-modified:Fri, 19 Dec 2025 22:15:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-943229

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7","display" : "Allelic phase"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"Allelic phase\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#311

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}],"text":"Genetic analysis report"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1158
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:00 GMT
last-modified:Fri, 19 Dec 2025 22:15:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-943233

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}],"text" : "Genetic analysis report"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#312

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:03 GMT
last-modified:Fri, 19 Dec 2025 22:15:03 GMT
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x-request-id:252-943241

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA9633-4 ('Present')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n31 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n31 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n31 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n31 0    : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n31 0    : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n"}]}

#313

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:08 GMT
last-modified:Fri, 19 Dec 2025 22:15:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943252

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51969-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#314

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9","display":"Discrete genetic variant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:938
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:08 GMT
last-modified:Fri, 19 Dec 2025 22:15:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943256

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9","display" : "Discrete genetic variant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81252-9 (\"Discrete genetic variant\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81252-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#315

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"30880","display":"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
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date:Fri, 19 Dec 2025 22:15:08 GMT
last-modified:Fri, 19 Dec 2025 22:15:08 GMT
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x-request-id:252-943260

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "30880"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#30880 (\"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/clinvar#30880\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}

#316

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:09 GMT
last-modified:Fri, 19 Dec 2025 22:15:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-943262

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#317

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1572
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:09 GMT
last-modified:Fri, 19 Dec 2025 22:15:09 GMT
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server:nginx
x-request-id:252-943264

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}

#318

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:09 GMT
last-modified:Fri, 19 Dec 2025 22:15:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-943266

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#319

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:09 GMT
last-modified:Fri, 19 Dec 2025 22:15:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-943268

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#320

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:906
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:10 GMT
last-modified:Fri, 19 Dec 2025 22:15:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943271

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6690-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Substitution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6690-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#321

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:894
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:11 GMT
last-modified:Fri, 19 Dec 2025 22:15:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943275

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6683-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#322

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:906
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:11 GMT
last-modified:Fri, 19 Dec 2025 22:15:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943279

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#323

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1156
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:11 GMT
last-modified:Fri, 19 Dec 2025 22:15:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943282

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NC_000003.11:g.128625063C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#324

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1127
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:12 GMT
last-modified:Fri, 19 Dec 2025 22:15:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943285

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n15 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n15 0    : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n125 110 : 110ms : Code \"NM_014049.4:c.1249C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#325

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:12 GMT
last-modified:Fri, 19 Dec 2025 22:15:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943287

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n94 78   : 94ms : Code \"NP_054768.2:p.Arg417Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#326

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-cibuild","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2193
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:12 GMT
last-modified:Fri, 19 Dec 2025 22:15:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943289

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6690-7 ('Substitution')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://www.sequenceontology.org)(concept<<SO:0002072)\"\r\n16 0    : 0ms  : CodeSystem version  not found: \"http://www.sequenceontology.org\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA6690-7\"\r\n"}]}

#327

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1169
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:12 GMT
last-modified:Fri, 19 Dec 2025 22:15:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943290

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL378-1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL378-1)\"\r\n15 15   : 15ms : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 15ms : Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n15 0    : 15ms : Check \"http://loinc.org#LA6683-2\"\r\n15 0    : 15ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 15ms : check code in (http://loinc.org)(LIST=LL378-1) at CodeableConcept.coding[0]\r\n15 0    : 15ms : Filter \"LIST=LL378-1\": Code \"LA6683-2\" found in http://loinc.org|2.81\r\n"}]}

#328

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1181
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:13 GMT
last-modified:Fri, 19 Dec 2025 22:15:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-943292

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://loinc.org/vs/LL381-5 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL381-5)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6706-1\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LIST=LL381-5) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Filter \"LIST=LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}

#329

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6668-3","display":"Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:13 GMT
last-modified:Fri, 19 Dec 2025 22:15:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-943293

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6668-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6668-3","display" : "Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6668-3 (\"Pathogenic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6668-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#330

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0012624","display":"acyl-CoA dehydrogenase 9 deficiency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1613
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:14 GMT
last-modified:Fri, 19 Dec 2025 22:15:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943294

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "code","valueCode" : "MONDO:0012624"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://purl.obolibrary.org/obo/mondo.owl#MONDO:0012624 (\"acyl-CoA dehydrogenase 9 deficiency\")]\"\r\n0 0     : 0ms  : Check \"http://purl.obolibrary.org/obo/mondo.owl#MONDO:0012624\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://purl.obolibrary.org/obo/mondo.owl\"\r\n"}]}

#331

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:14 GMT
last-modified:Fri, 19 Dec 2025 22:15:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943295

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#332

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:14 GMT
last-modified:Fri, 19 Dec 2025 22:15:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943297

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#333

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1122
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:14 GMT
last-modified:Fri, 19 Dec 2025 22:15:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943298

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n16 0    : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n125 109 : 109ms : Code \"NM_000106.5:c.886C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#334

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:15 GMT
last-modified:Fri, 19 Dec 2025 22:15:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943299

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n94 78   : 94ms : Code \"NP_000097.3:p.Arg296Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#335

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:15 GMT
last-modified:Fri, 19 Dec 2025 22:15:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943301

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#336

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:15 GMT
last-modified:Fri, 19 Dec 2025 22:15:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943302

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n15 15   : 15ms : Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n15 0    : 15ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 15ms : check code in (http://varnomen.hgvs.org) at Coding\r\n93 78   : 93ms : Code \"NM_000106.5:c.1457G>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#337

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"293498008","display":"Debrisoquine adverse reaction (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:15 GMT
last-modified:Fri, 19 Dec 2025 22:15:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943303

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "293498008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Debrisoquine adverse reaction"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "293498008","display" : "Debrisoquine adverse reaction (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#293498008 (\"Debrisoquine adverse reaction (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#293498008\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#338

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1239
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:16 GMT
last-modified:Fri, 19 Dec 2025 22:15:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943304

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4049-4 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4049-4)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4049-4) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}

#339

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2260
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:16 GMT
last-modified:Fri, 19 Dec 2025 22:15:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943306

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n15 15   : 15ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 15ms : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n15 0    : 15ms : Filter \"LIST=LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}

#340

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C43359","display":"Group"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:859
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:16 GMT
last-modified:Fri, 19 Dec 2025 22:15:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943307

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C43359"},{"name" : "display","valueString" : "Group"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43359 (\"Group\")]\"\r\n0 0     : 0ms  : Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43359\"\r\n0 0     : 0ms  : Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.32.0)\" (content = fragment)\r\n"}]}

#341

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"HLA-A*02:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1523
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:16 GMT
last-modified:Fri, 19 Dec 2025 22:15:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943308

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*02:01"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla#HLA-A*02:01\"\r\n16 0    : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}

#342

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00538","display":"CYP2C9*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1449
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:17 GMT
last-modified:Fri, 19 Dec 2025 22:15:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943309

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00538"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.pharmvar.org#PV00538 (\"CYP2C9*2\")]\"\r\n0 0     : 0ms  : Check \"http://www.pharmvar.org#PV00538\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}

#343

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"Warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1013
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:17 GMT
last-modified:Fri, 19 Dec 2025 22:15:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943310

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "Warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"Warfarin\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#344

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:17 GMT
last-modified:Fri, 19 Dec 2025 22:15:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943312

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA25390-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#345

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
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content-length:1796
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:18 GMT
last-modified:Fri, 19 Dec 2025 22:15:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943313

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA25390-8\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"LA25390-8\" found in http://loinc.org|2.81\r\n"}]}

#346

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:897
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:18 GMT
last-modified:Fri, 19 Dec 2025 22:15:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943314

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6676-6 (\"Resistant\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6676-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#347

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1767
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:18 GMT
last-modified:Fri, 19 Dec 2025 22:15:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943316

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6676-6 (\"Resistant\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6676-6\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA6676-6\" found in http://loinc.org|2.81\r\n"}]}

#348

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:894
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:19 GMT
last-modified:Fri, 19 Dec 2025 22:15:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-943317

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6576-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Positive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6576-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#349

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1032
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:19 GMT
last-modified:Fri, 19 Dec 2025 22:15:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-943320

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "10828004"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Positive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "10828004","display" : "Positive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#10828004 (\"Positive\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#10828004\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#350

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:7a249267-2bf8-4911-b799-66c83564ed69","status":"active","compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing urn:uuid:7a249267-2bf8-4911-b799-66c83564ed69 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(urn:ietf:bcp:13)\"\r\n0 0     : 0ms  : CodeSystem found: \"urn:ietf:bcp:13|\"\r\n0 0     : 0ms  : Validate \"[#text/plain (\"\")]\" and infer system\r\n0 0     : 0ms  : Check \"#text/plain\"\r\n0 0     : 0ms  : Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n0 0     : 0ms  : CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n0 0     : 0ms  : check code in (urn:ietf:bcp:13) at \r\n0 0     : 0ms  : Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}

#351

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
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{"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"mimetypes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/mimetypes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1024"}],"version":"6.0.0-ballot3","name":"MimeTypes","title":"Mime Types","status":"active","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International - FHIR-Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all possible codes from BCP-13 (see http://tools.ietf.org/html/bcp13)","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(urn:ietf:bcp:13)\"\r\n16 0    : 0ms  : CodeSystem found: \"urn:ietf:bcp:13|\"\r\n16 0    : 0ms  : Validate \"[#text/plain (\"\")]\" and infer system\r\n16 0    : 0ms  : Check \"#text/plain\"\r\n16 0    : 0ms  : Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n16 0    : 0ms  : CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n16 0    : 0ms  : check code in (urn:ietf:bcp:13) at \r\n16 0    : 0ms  : Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}

#352

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA19542-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#353

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA19542-2\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"LA19542-2\" found in http://loinc.org|2.81\r\n"}]}

#354

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":4}],"url":"http://hl7.org/fhir/ValueSet/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1396"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://hl7.org/fhir/CodeSystem/task-code","version":"6.0.0-ballot3"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablecodesystem"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/CodeSystem/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.4.1397"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"HL7 International","description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"valueSet":"http://hl7.org/fhir/ValueSet/task-code.html","content":"complete","concept":[{"code":"approve","display":"Activate/approve the focal resource","definition":"Take what actions are needed to transition the focus resource from 'draft' to 'active' or 'in-progress', as appropriate for the resource type.  This may involve additing additional content, approval, validation, etc."},{"code":"fulfill","display":"Fulfill the focal request","definition":"Act to perform the actions described in the focus request.  This might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events.  The degree of fulfillment requested might be limited by Task.restriction."},{"code":"instantiate","display":"Instantiate the focal definition","definition":"Act to perform the actions defined in the focus definition resource (ActivityDefinition, PlanDefinition, Questionnaire, etc.)  For PlanDefinition or ActivityDefinition, this might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events.  For Questionnaire, this would result in a QuestionnaireResponse - and possibly resources constructed using data extracted from the response.  The degree of fulfillment requested might be limited by Task.restriction."},{"code":"abort","display":"Mark the focal resource as no longer active","definition":"Abort, cancel or withdraw the focal resource, as appropriate for the type of resource."},{"code":"replace","display":"Replace the focal resource with the input resource","definition":"Replace the focal resource with the specified input resource"},{"code":"change","display":"Change the focal resource","definition":"Update the focal resource of the owning system to reflect the content specified as the Task.focus"},{"code":"suspend","display":"Suspend the focal resource","definition":"Transition the focal resource from 'active' or 'in-progress' to 'suspended'"},{"code":"resume","display":"Re-activate the focal resource","definition":"Transition the focal resource from 'suspended' to 'active' or 'in-progress' as appropriate for the resource type."}]}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Fri, 19 Dec 2025 22:15:21 GMT
pragma:no-cache
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x-request-id:252-943330

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://hl7.org/fhir/CodeSystem/task-code)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://hl7.org/fhir/CodeSystem/task-code|6.0.0-ballot3\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n"}]}

#355

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 19 Dec 2025 22:15:21 GMT
last-modified:Fri, 19 Dec 2025 22:15:21 GMT
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server:nginx
x-request-id:252-943331

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}

#356

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1754
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:21 GMT
last-modified:Fri, 19 Dec 2025 22:15:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-943332

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "version","valueString" : "137"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP|137\"\r\n"}]}

#357

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81299-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:893
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:22 GMT
last-modified:Fri, 19 Dec 2025 22:15:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-943334

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81299-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81299-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#358

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81300-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:878
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:22 GMT
last-modified:Fri, 19 Dec 2025 22:15:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-943338

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81300-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81300-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#359

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","version":"???","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1744
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:23 GMT
last-modified:Fri, 19 Dec 2025 22:15:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-943342

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "38486"},{"name" : "version","valueString" : "???"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ncbi.nlm.nih.gov/clinvar|???#38486 (\"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)\")]\"\r\n0 0     : 0ms  : Check \"http://www.ncbi.nlm.nih.gov/clinvar|???#38486\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar|???\"\r\n"}]}

#360

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript ref sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:952
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:24 GMT
last-modified:Fri, 19 Dec 2025 22:15:24 GMT
pragma:no-cache
server:nginx
x-request-id:252-943349

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript ref sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"Transcript ref sequence ID\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#361

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:25 GMT
last-modified:Fri, 19 Dec 2025 22:15:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-943350

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"Genomic ref allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#362

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:25 GMT
last-modified:Fri, 19 Dec 2025 22:15:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-943352

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"Genomic alt allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#363

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6","display":"DNA change (c.HGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:923
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:26 GMT
last-modified:Fri, 19 Dec 2025 22:15:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-943353

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6","display" : "DNA change (c.HGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"DNA change (c.HGVS)\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#364

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A","display":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:26 GMT
last-modified:Fri, 19 Dec 2025 22:15:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-943354

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"NM_022787.3:c.769G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#365

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:26 GMT
last-modified:Fri, 19 Dec 2025 22:15:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-943355

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_022787.3:c.769G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#366

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G","display":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:835
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:26 GMT
last-modified:Fri, 19 Dec 2025 22:15:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-943356

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"NM_022787.3:c.53A>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#367

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1116
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:27 GMT
last-modified:Fri, 19 Dec 2025 22:15:27 GMT
pragma:no-cache
server:nginx
x-request-id:252-943357

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_022787.3:c.53A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#368

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94076-7","display":"Mutations/Megabase [# Ratio] in Tumor"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:977
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:27 GMT
last-modified:Fri, 19 Dec 2025 22:15:27 GMT
pragma:no-cache
server:nginx
x-request-id:252-943359

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94076-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Mutations/Megabase [# Ratio] in Tumor"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94076-7","display" : "Mutations/Megabase [# Ratio] in Tumor"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94076-7 (\"Mutations/Megabase [# Ratio] in Tumor\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94076-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#369

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:904
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:28 GMT
last-modified:Fri, 19 Dec 2025 22:15:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-943361

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26398-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#370

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9","display":"Genomic DNA change (gHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:28 GMT
last-modified:Fri, 19 Dec 2025 22:15:28 GMT
pragma:no-cache
server:nginx
x-request-id:252-943364

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9","display" : "Genomic DNA change (gHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"Genomic DNA change (gHGVS)\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#371

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T","display":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:875
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:29 GMT
last-modified:Fri, 19 Dec 2025 22:15:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-943366

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"NC_000007.13:g.140453136A>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#372

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3","display":"Amino acid change (pHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:941
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:29 GMT
last-modified:Fri, 19 Dec 2025 22:15:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-943369

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3","display" : "Amino acid change (pHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"Amino acid change (pHGVS)\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#373

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu","display":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:29 GMT
last-modified:Fri, 19 Dec 2025 22:15:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-943372

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"NP_004324.2:p.Val600Glu\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#374

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:913
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:30 GMT
last-modified:Fri, 19 Dec 2025 22:15:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-943375

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"Gene studied ID\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#375

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1184
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:30 GMT
last-modified:Fri, 19 Dec 2025 22:15:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-943378

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4048-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4048-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26398-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4048-6) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4048-6\": Code \"LA26398-0\" found in http://loinc.org|2.81\r\n"}]}

#376

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1157
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:31 GMT
last-modified:Fri, 19 Dec 2025 22:15:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-943380

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n16 16   : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n110 94  : 110ms : Code \"NC_000007.13:g.140453136A>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#377

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1137
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:31 GMT
last-modified:Fri, 19 Dec 2025 22:15:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-943382

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NP_004324.2:p.Val600Glu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#378

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:31 GMT
last-modified:Fri, 19 Dec 2025 22:15:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-943383

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26811-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#379

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8","display":"Genetic variation clinical significance [Imp]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1001
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:32 GMT
last-modified:Fri, 19 Dec 2025 22:15:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943384

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8","display" : "Genetic variation clinical significance [Imp]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"Genetic variation clinical significance [Imp]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#380

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of Evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:917
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:32 GMT
last-modified:Fri, 19 Dec 2025 22:15:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943386

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of Evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"Level of Evidence\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#381

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30200-2","display":"Very strong evidence pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:967
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:33 GMT
last-modified:Fri, 19 Dec 2025 22:15:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943388

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30200-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Very strong evidence pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30200-2","display" : "Very strong evidence pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30200-2 (\"Very strong evidence pathogenic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30200-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#382

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2205
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:33 GMT
last-modified:Fri, 19 Dec 2025 22:15:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943389

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26398-0 ('Sequencing')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26398-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4050-2\": Code \"LA26398-0\" not found in http://loinc.org|2.81\r\n"}]}

#383

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1220
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:33 GMT
last-modified:Fri, 19 Dec 2025 22:15:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943391

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4048-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4048-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26811-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4048-6) at CodeableConcept.coding[0]\r\n16 16   : 16ms : Filter \"LIST=LL4048-6\": Code \"LA26811-2\" found in http://loinc.org|2.81\r\n"}]}

#384

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2241
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:34 GMT
last-modified:Fri, 19 Dec 2025 22:15:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943392

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26811-2 ('Computational analysis')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26811-2\"\r\n16 16   : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n16 0    : 16ms : Filter \"LIST=LL4050-2\": Code \"LA26811-2\" not found in http://loinc.org|2.81\r\n"}]}

#385

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:989
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:34 GMT
last-modified:Fri, 19 Dec 2025 22:15:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943393

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://hl7.org/fhir/sid/icd-10-cm","code" : "C16.0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n16 0    : 0ms  : Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.32.0)\" (content = complete)\r\n"}]}

#386

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:933
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:35 GMT
last-modified:Fri, 19 Dec 2025 22:15:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943394

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"Genomic source class\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#387

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:35 GMT
last-modified:Fri, 19 Dec 2025 22:15:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943396

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6684-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#388

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G","display":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:35 GMT
last-modified:Fri, 19 Dec 2025 22:15:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943397

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"NM_006218.4:c.3140A>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#389

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA change type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:36 GMT
last-modified:Fri, 19 Dec 2025 22:15:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943399

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA change type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"DNA change type\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#390

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1518
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:36 GMT
last-modified:Fri, 19 Dec 2025 22:15:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943401

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.sequenceontology.org#SO:1000002 (\"substitution\")]\"\r\n0 0     : 0ms  : Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}

#391

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg","display":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:36 GMT
last-modified:Fri, 19 Dec 2025 22:15:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943402

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"NP_006209.2:p.His1047Arg\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#392

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:968
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:37 GMT
last-modified:Fri, 19 Dec 2025 22:15:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-943403

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"Transcript reference sequence [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#393

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6","display":"Sample VAF"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:924
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:37 GMT
last-modified:Fri, 19 Dec 2025 22:15:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-943404

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6","display" : "Sample VAF"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"Sample VAF\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#394

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5","display":"Allelic read depth"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:920
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:38 GMT
last-modified:Fri, 19 Dec 2025 22:15:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-943406

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5","display" : "Allelic read depth"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"Allelic read depth\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#395

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1166
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:38 GMT
last-modified:Fri, 19 Dec 2025 22:15:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-943408

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL378-1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL378-1)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6684-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL378-1) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL378-1\": Code \"LA6684-0\" found in http://loinc.org|2.81\r\n"}]}

#396

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:38 GMT
last-modified:Fri, 19 Dec 2025 22:15:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-943409

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_006218.4:c.3140A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#397

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1142
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:39 GMT
last-modified:Fri, 19 Dec 2025 22:15:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943410

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NP_006209.2:p.His1047Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#398

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T","display":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:835
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:39 GMT
last-modified:Fri, 19 Dec 2025 22:15:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943411

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"NM_002524.4:c.34G>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#399

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1117
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:39 GMT
last-modified:Fri, 19 Dec 2025 22:15:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943413

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_002524.4:c.34G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#400

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A","display":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:39 GMT
last-modified:Fri, 19 Dec 2025 22:15:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943414

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"NM_001349798.2:c.1394G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#401

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His","display":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:40 GMT
last-modified:Fri, 19 Dec 2025 22:15:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-943415

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"NP_001336727.1:p.Arg465His\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#402

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:40 GMT
last-modified:Fri, 19 Dec 2025 22:15:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-943416

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NM_001349798.2:c.1394G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#403

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:40 GMT
last-modified:Fri, 19 Dec 2025 22:15:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-943418

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NP_001336727.1:p.Arg465His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#404

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA","display":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:880
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:40 GMT
last-modified:Fri, 19 Dec 2025 22:15:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-943419

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"NM_003482.3:c.7900_7901delCA\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#405

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1161
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:41 GMT
last-modified:Fri, 19 Dec 2025 22:15:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-943420

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_003482.3:c.7900_7901delCA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#406

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T","display":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:41 GMT
last-modified:Fri, 19 Dec 2025 22:15:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-943424

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"NM_006218.3:c.333G>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#407

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:41 GMT
last-modified:Fri, 19 Dec 2025 22:15:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-943425

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_006218.3:c.333G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#408

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T","display":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:42 GMT
last-modified:Fri, 19 Dec 2025 22:15:42 GMT
pragma:no-cache
server:nginx
x-request-id:252-943428

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"NM_003749.2:c.3960C>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#409

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1127
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:42 GMT
last-modified:Fri, 19 Dec 2025 22:15:42 GMT
pragma:no-cache
server:nginx
x-request-id:252-943429

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_003749.2:c.3960C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#410

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:42 GMT
last-modified:Fri, 19 Dec 2025 22:15:42 GMT
pragma:no-cache
server:nginx
x-request-id:252-943433

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#411

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:43 GMT
last-modified:Fri, 19 Dec 2025 22:15:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-943435

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#412

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:43 GMT
last-modified:Fri, 19 Dec 2025 22:15:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-943437

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_000077.4:c.9_32del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#413

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1157
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:43 GMT
last-modified:Fri, 19 Dec 2025 22:15:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-943440

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NP_000068.1:p.Ala4_Pro11del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#414

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:44 GMT
last-modified:Fri, 19 Dec 2025 22:15:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-943443

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#415

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:44 GMT
last-modified:Fri, 19 Dec 2025 22:15:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-943445

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#416

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:44 GMT
last-modified:Fri, 19 Dec 2025 22:15:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-943448

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_004260.4:c.2086C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#417

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:44 GMT
last-modified:Fri, 19 Dec 2025 22:15:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-943450

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NP_004251.4:p.Arg696Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#418

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:45 GMT
last-modified:Fri, 19 Dec 2025 22:15:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943452

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#419

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:836
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:45 GMT
last-modified:Fri, 19 Dec 2025 22:15:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943455

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#420

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1127
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:45 GMT
last-modified:Fri, 19 Dec 2025 22:15:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943457

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_000540.3:c.4964G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#421

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:45 GMT
last-modified:Fri, 19 Dec 2025 22:15:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943458

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NP_000531.2:p.Arg1655Leu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#422

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:828
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:46 GMT
last-modified:Fri, 19 Dec 2025 22:15:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943460

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#423

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1132
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:46 GMT
last-modified:Fri, 19 Dec 2025 22:15:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943463

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_014363.5:c.12118G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#424

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:46 GMT
last-modified:Fri, 19 Dec 2025 22:15:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943465

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#425

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:47 GMT
last-modified:Fri, 19 Dec 2025 22:15:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943466

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NM_004787.3:c.1290C>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#426

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:47 GMT
last-modified:Fri, 19 Dec 2025 22:15:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943467

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#427

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:47 GMT
last-modified:Fri, 19 Dec 2025 22:15:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943470

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#428

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1127
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:47 GMT
last-modified:Fri, 19 Dec 2025 22:15:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943472

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_003072.5:c.2372C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#429

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1137
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:48 GMT
last-modified:Fri, 19 Dec 2025 22:15:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-943474

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NP_003063.2:p.Ala791Val\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#430

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81695-9","display":"Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1088
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:50 GMT
last-modified:Fri, 19 Dec 2025 22:15:50 GMT
pragma:no-cache
server:nginx
x-request-id:252-943484

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81695-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81695-9","display" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81695-9 (\"Microsatellite instability [Interpretation] in Cancer specimen Qualitative\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81695-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#431

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:50 GMT
last-modified:Fri, 19 Dec 2025 22:15:50 GMT
pragma:no-cache
server:nginx
x-request-id:252-943488

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14122-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Stable"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14122-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#432

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T","display":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:865
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:51 GMT
last-modified:Fri, 19 Dec 2025 22:15:51 GMT
pragma:no-cache
server:nginx
x-request-id:252-943492

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"NC_000009.12:g.5073770G>T\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#433

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe","display":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:51 GMT
last-modified:Fri, 19 Dec 2025 22:15:51 GMT
pragma:no-cache
server:nginx
x-request-id:252-943493

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"NP_004963.1:p.Val617Phe\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#434

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:51 GMT
last-modified:Fri, 19 Dec 2025 22:15:51 GMT
pragma:no-cache
server:nginx
x-request-id:252-943495

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NC_000009.12:g.5073770G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#435

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:52 GMT
last-modified:Fri, 19 Dec 2025 22:15:52 GMT
pragma:no-cache
server:nginx
x-request-id:252-943496

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NP_004963.1:p.Val617Phe\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#436

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A","display":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:52 GMT
last-modified:Fri, 19 Dec 2025 22:15:52 GMT
pragma:no-cache
server:nginx
x-request-id:252-943498

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"NC_000004.11:g.55972974T>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#437

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His","display":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:52 GMT
last-modified:Fri, 19 Dec 2025 22:15:52 GMT
pragma:no-cache
server:nginx
x-request-id:252-943499

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"NP_002244.1:p.Gln472His\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#438

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:53 GMT
last-modified:Fri, 19 Dec 2025 22:15:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943500

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NC_000004.11:g.55972974T>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#439

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1137
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:53 GMT
last-modified:Fri, 19 Dec 2025 22:15:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943502

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NP_002244.1:p.Gln472His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#440

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del","display":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:53 GMT
last-modified:Fri, 19 Dec 2025 22:15:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943503

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"NC_000002.12:g.211713666_211713668del\")]\"\r\n15 0    : 0ms  : Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n15 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#441

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1206
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:53 GMT
last-modified:Fri, 19 Dec 2025 22:15:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943505

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NC_000002.12:g.211713666_211713668del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#442

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"1193326","display":"Ruxolitinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1030
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:54 GMT
last-modified:Fri, 19 Dec 2025 22:15:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943506

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "1193326"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "ruxolitinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "1193326","display" : "Ruxolitinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#1193326 (\"Ruxolitinib\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#1193326\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#443

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:54 GMT
last-modified:Fri, 19 Dec 2025 22:15:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943507

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#444

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1770
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:54 GMT
last-modified:Fri, 19 Dec 2025 22:15:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943509

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#445

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7","display":"Medication assessed"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:55 GMT
last-modified:Fri, 19 Dec 2025 22:15:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-943510

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7","display" : "Medication assessed"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"Medication assessed\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#446

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2193
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:55 GMT
last-modified:Fri, 19 Dec 2025 22:15:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-943512

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA14122-8\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1971-2\": Code \"LA14122-8\" not found in http://loinc.org|2.81\r\n"}]}

#447

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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200
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date:Fri, 19 Dec 2025 22:15:56 GMT
last-modified:Fri, 19 Dec 2025 22:15:56 GMT
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x-request-id:252-943513

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA14122-8\"\r\n"}]}

#448

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:57 GMT
last-modified:Fri, 19 Dec 2025 22:15:57 GMT
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x-request-id:252-943523

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4049-4 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4049-4)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4049-4) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}

#449

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"103","display":"mercaptopurine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:58 GMT
last-modified:Fri, 19 Dec 2025 22:15:58 GMT
pragma:no-cache
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x-request-id:252-943525

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "103"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "mercaptopurine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "103","display" : "mercaptopurine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#103 (\"mercaptopurine\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#103\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#450

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Fri, 19 Dec 2025 22:15:58 GMT
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x-request-id:252-943527

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Filter \"LIST=LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}

#451

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 19 Dec 2025 22:15:58 GMT
last-modified:Fri, 19 Dec 2025 22:15:58 GMT
pragma:no-cache
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x-request-id:252-943529

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"genotype display name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#452

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype Name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:15:59 GMT
last-modified:Fri, 19 Dec 2025 22:15:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-943532

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype Name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"Haplotype Name\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#453

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://hl7.org/fhir/CodeSystem/task-code)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://hl7.org/fhir/CodeSystem/task-code|6.0.0-ballot3\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA26423-6\"\r\n"}]}

#454

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"706687001","display":"Software (physical object)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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x-request-id:252-943541

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "706687001"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Software"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "706687001","display" : "Software (physical object)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#706687001 (\"Software (physical object)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#706687001\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#455

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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#456

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2002","display":"Carbamazepine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2002"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "carbamazepine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2002","display" : "Carbamazepine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2002 (\"Carbamazepine\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2002\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#457

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA19541-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA19541-4\" found in http://loinc.org|2.81\r\n"}]}

#458

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://loinc.org","code":"57979-7","display":"HLA-B*15:02 [Presence]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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server:nginx
x-request-id:252-943549

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57979-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-B*15:02 [Presence]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://loinc.org","code" : "57979-7","display" : "HLA-B*15:02 [Presence]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 16   : 16ms : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 16ms : Validate \"[http://loinc.org#51969-4 (\"\"), http://loinc.org#57979-7 (\"HLA-B*15:02 [Presence]\")]\"\r\n16 0    : 16ms : Check \"http://loinc.org#51969-4\"\r\n16 0    : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 16ms : Code \"51969-4\" found in http://loinc.org|2.81\r\n16 0    : 16ms : Check \"http://loinc.org#57979-7\"\r\n16 0    : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org) at CodeableConcept.coding[1]\r\n16 0    : 16ms : Code \"57979-7\" found in http://loinc.org|2.81\r\n"}]}

#459

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2912
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:02 GMT
last-modified:Fri, 19 Dec 2025 22:16:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-943550

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://example.org/hgsc.bcm.edu/lab-test-codes/","code" : "emerge-seq-ngs-pnl"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[1].code"],"expression" : ["CodeableConcept.coding[1].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["CodeableConcept.coding[1].system"],"expression" : ["CodeableConcept.coding[1].system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3 for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\"), http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n15 0    : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n"}]}

#460

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:952
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:02 GMT
last-modified:Fri, 19 Dec 2025 22:16:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-943553

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#461

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1232
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:02 GMT
last-modified:Fri, 19 Dec 2025 22:16:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-943557

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30102-0\"\r\n16 16   : 16ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 16ms : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n16 0    : 16ms : Filter \"LIST=LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}

#462

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:03 GMT
last-modified:Fri, 19 Dec 2025 22:16:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-943560

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#463

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:03 GMT
last-modified:Fri, 19 Dec 2025 22:16:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-943561

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n15 0    : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n15 0    : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n15 0    : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 94  : 94ms : Code \"NC_000010.10:g.96540410G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#464

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"32968","display":"clopidogrel"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1022
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:04 GMT
last-modified:Fri, 19 Dec 2025 22:16:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-943563

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "32968"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "clopidogrel"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "32968","display" : "clopidogrel"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#32968 (\"clopidogrel\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#32968\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#465

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:918
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:04 GMT
last-modified:Fri, 19 Dec 2025 22:16:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-943564

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9657-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#466

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-length:1788
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:04 GMT
last-modified:Fri, 19 Dec 2025 22:16:04 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA9657-3\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"LA9657-3\" found in http://loinc.org|2.81\r\n"}]}

#467

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"121243","display":"voriconazole"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1029
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:04 GMT
last-modified:Fri, 19 Dec 2025 22:16:04 GMT
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server:nginx
x-request-id:252-943569

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "121243"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "voriconazole"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "121243","display" : "voriconazole"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#121243 (\"voriconazole\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#121243\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#468

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2556","display":"citalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
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content-length:1015
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:05 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2556"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "citalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2556","display" : "citalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2556 (\"citalopram\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2556\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#469

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"321988","display":"escitalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "321988"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "escitalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "321988","display" : "escitalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#321988 (\"escitalopram\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#321988\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#470

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"704","display":"amitriptyline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1020
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:05 GMT
last-modified:Fri, 19 Dec 2025 22:16:05 GMT
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x-request-id:252-943574

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "704"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "amitriptyline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "704","display" : "amitriptyline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#704 (\"amitriptyline\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#704\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#471

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
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content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:05 GMT
last-modified:Fri, 19 Dec 2025 22:16:05 GMT
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x-request-id:252-943576

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#472

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:06 GMT
last-modified:Fri, 19 Dec 2025 22:16:06 GMT
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server:nginx
x-request-id:252-943577

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NC_000016.9:g.31096368G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#473

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1013
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:06 GMT
last-modified:Fri, 19 Dec 2025 22:16:06 GMT
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x-request-id:252-943578

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"warfarin\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#474

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
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x-request-id:252-943579

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#475

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA25391-6\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"LA25391-6\" found in http://loinc.org|2.81\r\n"}]}

#476

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://example.org/hgsc.bcm.edu/lab-test-codes/","code" : "emerge-seq-ngs-pnl"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[1].code"],"expression" : ["CodeableConcept.coding[1].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["CodeableConcept.coding[1].system"],"expression" : ["CodeableConcept.coding[1].system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3 for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#51969-4 (\"\"), http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#51969-4\"\r\n16 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0    : 0ms  : check code in (http://loinc.org) at CodeableConcept.coding[0]\r\n16 0    : 0ms  : Code \"51969-4\" found in http://loinc.org|2.81\r\n16 0    : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n"}]}

#477

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"Haplotype name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n360 360 : 360ms : Check \"http://loinc.org#57290-9\"\r\n360 0   : 360ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#478

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}

#479

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"Genotype display name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n375 375 : 375ms : Check \"http://loinc.org#57290-9\"\r\n375 0   : 375ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#480

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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server:nginx
x-request-id:252-943600

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#481

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:11 GMT
last-modified:Fri, 19 Dec 2025 22:16:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943601

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#482

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:12 GMT
last-modified:Fri, 19 Dec 2025 22:16:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943603

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#483

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:12 GMT
last-modified:Fri, 19 Dec 2025 22:16:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943607

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21262-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#484

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:848
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:12 GMT
last-modified:Fri, 19 Dec 2025 22:16:12 GMT
pragma:no-cache
server:nginx
x-request-id:252-943610

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#485

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:13 GMT
last-modified:Fri, 19 Dec 2025 22:16:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-943613

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NP_060087.3:p.A1931T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#486

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1127
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:13 GMT
last-modified:Fri, 19 Dec 2025 22:16:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-943616

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NM_017617.5:c.5791G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#487

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1190
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:13 GMT
last-modified:Fri, 19 Dec 2025 22:16:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-943617

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21262-3\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL2938-0\": Code \"LA21262-3\" found in http://loinc.org|2.81\r\n"}]}

#488

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1156
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:13 GMT
last-modified:Fri, 19 Dec 2025 22:16:13 GMT
pragma:no-cache
server:nginx
x-request-id:252-943619

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NC_000009.11:g.139395147C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#489

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:816
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:14 GMT
last-modified:Fri, 19 Dec 2025 22:16:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943621

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#490

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:14 GMT
last-modified:Fri, 19 Dec 2025 22:16:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943623

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#491

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:913
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:15 GMT
last-modified:Fri, 19 Dec 2025 22:16:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943624

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21269-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#492

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:15 GMT
last-modified:Fri, 19 Dec 2025 22:16:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943627

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#493

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1117
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:15 GMT
last-modified:Fri, 19 Dec 2025 22:16:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943629

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NP_008816.3:p.G585S\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#494

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:15 GMT
last-modified:Fri, 19 Dec 2025 22:16:15 GMT
pragma:no-cache
server:nginx
x-request-id:252-943631

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 16   : 16ms : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0    : 16ms : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 16ms : check code in (http://varnomen.hgvs.org) at Coding\r\n94 78   : 94ms : Code \"NM_006885.4:c.1753G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#495

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1193
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:16 GMT
last-modified:Fri, 19 Dec 2025 22:16:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943634

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21269-8\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL2938-0\": Code \"LA21269-8\" found in http://loinc.org|2.81\r\n"}]}

#496

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1147
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:16 GMT
last-modified:Fri, 19 Dec 2025 22:16:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943636

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NC_000016.9:g.72992292C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#497

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:16 GMT
last-modified:Fri, 19 Dec 2025 22:16:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943638

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#498

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:16 GMT
last-modified:Fri, 19 Dec 2025 22:16:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943641

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#499

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:17 GMT
last-modified:Fri, 19 Dec 2025 22:16:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943643

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#500

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:17 GMT
last-modified:Fri, 19 Dec 2025 22:16:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943645

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NP_002519.2:p.Trp243Ter\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#501

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1122
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:17 GMT
last-modified:Fri, 19 Dec 2025 22:16:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943648

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_002528.7:c.728G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#502

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1146
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:17 GMT
last-modified:Fri, 19 Dec 2025 22:16:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943650

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NC_000016.10:g.2040196C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#503

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:820
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:18 GMT
last-modified:Fri, 19 Dec 2025 22:16:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943652

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#504

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:900
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:18 GMT
last-modified:Fri, 19 Dec 2025 22:16:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943653

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#505

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:18 GMT
last-modified:Fri, 19 Dec 2025 22:16:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943654

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21276-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#506

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:944
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:19 GMT
last-modified:Fri, 19 Dec 2025 22:16:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-943656

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#507

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1121
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:19 GMT
last-modified:Fri, 19 Dec 2025 22:16:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-943658

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NP_006594.3:p.S1178*\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#508

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1222
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:19 GMT
last-modified:Fri, 19 Dec 2025 22:16:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-943660

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NM_006603.5:c.3530_3531insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#509

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1190
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:19 GMT
last-modified:Fri, 19 Dec 2025 22:16:19 GMT
pragma:no-cache
server:nginx
x-request-id:252-943661

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21276-3\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL2938-0\": Code \"LA21276-3\" found in http://loinc.org|2.81\r\n"}]}

#510

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1276
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:20 GMT
last-modified:Fri, 19 Dec 2025 22:16:20 GMT
pragma:no-cache
server:nginx
x-request-id:252-943662

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#511

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:864
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:20 GMT
last-modified:Fri, 19 Dec 2025 22:16:20 GMT
pragma:no-cache
server:nginx
x-request-id:252-943663

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#512

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:20 GMT
last-modified:Fri, 19 Dec 2025 22:16:20 GMT
pragma:no-cache
server:nginx
x-request-id:252-943666

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21256-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#513

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:908
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:21 GMT
last-modified:Fri, 19 Dec 2025 22:16:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-943669

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#514

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1177
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:21 GMT
last-modified:Fri, 19 Dec 2025 22:16:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-943671

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NM_001184.4:c.2878_2879insAGTAA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#515

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1190
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:21 GMT
last-modified:Fri, 19 Dec 2025 22:16:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-943672

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL2938-0 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL2938-0)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA21256-5\"\r\n15 15   : 15ms : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 15ms : check code in (http://loinc.org)(LIST=LL2938-0) at CodeableConcept.coding[0]\r\n15 0    : 15ms : Filter \"LIST=LL2938-0\": Code \"LA21256-5\" found in http://loinc.org|2.81\r\n"}]}

#516

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1232
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:21 GMT
last-modified:Fri, 19 Dec 2025 22:16:21 GMT
pragma:no-cache
server:nginx
x-request-id:252-943673

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NC_000003.11:g.142269071_142269072insTTACT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#517

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:832
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:22 GMT
last-modified:Fri, 19 Dec 2025 22:16:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-943675

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#518

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:824
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:22 GMT
last-modified:Fri, 19 Dec 2025 22:16:22 GMT
pragma:no-cache
server:nginx
x-request-id:252-943677

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#519

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:844
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:23 GMT
last-modified:Fri, 19 Dec 2025 22:16:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-943678

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#520

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1137
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:23 GMT
last-modified:Fri, 19 Dec 2025 22:16:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-943679

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 110 : 110ms : Code \"NP_005219.2:p.Leu858Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#521

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:23 GMT
last-modified:Fri, 19 Dec 2025 22:16:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-943680

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n16 0    : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n110 94  : 94ms : Code \"NM_005228.4:c.2573T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#522

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1151
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:23 GMT
last-modified:Fri, 19 Dec 2025 22:16:23 GMT
pragma:no-cache
server:nginx
x-request-id:252-943681

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n16 0    : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n16 0    : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 93  : 93ms : Code \"NC_000007.13:g.55259515T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#523

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26333-7","display":"Uncertain Significance"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:24 GMT
last-modified:Fri, 19 Dec 2025 22:16:24 GMT
pragma:no-cache
server:nginx
x-request-id:252-943682

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26333-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Uncertain significance"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26333-7","display" : "Uncertain Significance"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA26333-7 (\"Uncertain Significance\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA26333-7\"\r\n15 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#524

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4","display":"Associated phenotype"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:926
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:25 GMT
last-modified:Fri, 19 Dec 2025 22:16:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-943683

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4","display" : "Associated phenotype"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"Associated phenotype\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#525

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"699346009","display":"Hereditary cancer-predisposing syndrome (disorder)"}],"text":"Hereditary cancer-predisposing syndrome"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1193
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:25 GMT
last-modified:Fri, 19 Dec 2025 22:16:25 GMT
pragma:no-cache
server:nginx
x-request-id:252-943684

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "699346009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Hereditary neoplastic syndrome"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "699346009","display" : "Hereditary cancer-predisposing syndrome (disorder)"}],"text" : "Hereditary cancer-predisposing syndrome"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#699346009 (\"Hereditary cancer-predisposing syndrome (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#699346009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#526

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26332-9","display":"Likely Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:26 GMT
last-modified:Fri, 19 Dec 2025 22:16:26 GMT
pragma:no-cache
server:nginx
x-request-id:252-943685

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26332-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Likely pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26332-9","display" : "Likely Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26332-9 (\"Likely Pathogenic\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26332-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#527

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
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last-modified:Fri, 19 Dec 2025 22:16:26 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"Level of evidence\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n15 15   : 15ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#528

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254637007","display":"Non-small cell lung cancer (disorder)"}],"text":"Non-small cell lung cancer"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254637007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Non-small cell lung cancer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254637007","display" : "Non-small cell lung cancer (disorder)"}],"text" : "Non-small cell lung cancer"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#254637007 (\"Non-small cell lung cancer (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#254637007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#529

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT04919811","display":"NCT04919811"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Fri, 19 Dec 2025 22:16:27 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT04919811"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://clinicaltrials.gov#NCT04919811 (\"NCT04919811\")]\"\r\n0 0     : 0ms  : Check \"http://clinicaltrials.gov#NCT04919811\"\r\n15 15   : 15ms : Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}

#530

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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date:Fri, 19 Dec 2025 22:16:27 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#531

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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last-modified:Fri, 19 Dec 2025 22:16:27 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#532

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#533

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

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last-modified:Fri, 19 Dec 2025 22:16:28 GMT
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server:nginx
x-request-id:252-943698

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#LA6677-4\"\r\n15 0    : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0    : 0ms  : check code in (http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}

#534

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}],"text":"coding HGVS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:893
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:29 GMT
last-modified:Fri, 19 Dec 2025 22:16:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-943700

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}],"text" : "coding HGVS"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n15 15   : 15ms : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#535

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A","display":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:29 GMT
last-modified:Fri, 19 Dec 2025 22:16:29 GMT
pragma:no-cache
server:nginx
x-request-id:252-943705

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 16   : 16ms : Prepare include: \"()\"\r\n16 0    : 16ms : Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"NM_017617.5:c.5791G>A\")]\"\r\n16 0    : 16ms : Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n16 0    : 16ms : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#536

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T","display":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:30 GMT
last-modified:Fri, 19 Dec 2025 22:16:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-943707

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"NP_060087.3:p.A1931T\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#537

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A","display":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:30 GMT
last-modified:Fri, 19 Dec 2025 22:16:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-943708

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"NM_006885.4:c.1753G>A\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#538

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S","display":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:835
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:30 GMT
last-modified:Fri, 19 Dec 2025 22:16:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-943709

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"NP_008816.3:p.G585S\")]\"\r\n16 0    : 0ms  : Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n16 0    : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#539

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del","display":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:30 GMT
last-modified:Fri, 19 Dec 2025 22:16:30 GMT
pragma:no-cache
server:nginx
x-request-id:252-943710

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"NM_000251.3:c.1832del\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n15 15   : 15ms : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#540

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:31 GMT
last-modified:Fri, 19 Dec 2025 22:16:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-943711

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NM_000251.3:c.1832del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#541

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A","display":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:31 GMT
last-modified:Fri, 19 Dec 2025 22:16:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-943712

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"NM_002528.7:c.728G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#542

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter","display":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:31 GMT
last-modified:Fri, 19 Dec 2025 22:16:31 GMT
pragma:no-cache
server:nginx
x-request-id:252-943713

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"NP_002519.2:p.Trp243Ter\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#543

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT","display":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:940
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:32 GMT
last-modified:Fri, 19 Dec 2025 22:16:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943714

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"NM_006603.5:c.3530_3531insGTGACTATTAATAT\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#544

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*","display":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:840
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:32 GMT
last-modified:Fri, 19 Dec 2025 22:16:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943715

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"NP_006594.3:p.S1178*\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#545

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA","display":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:895
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:32 GMT
last-modified:Fri, 19 Dec 2025 22:16:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943716

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"NM_001184.4:c.2878_2879insAGTAA\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#546

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G","display":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:32 GMT
last-modified:Fri, 19 Dec 2025 22:16:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943717

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"NM_005228.4:c.2573T>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#547

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg","display":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:855
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:33 GMT
last-modified:Fri, 19 Dec 2025 22:16:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943718

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"NP_005219.2:p.Leu858Arg\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#548

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:889
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:33 GMT
last-modified:Fri, 19 Dec 2025 22:16:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943719

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26203-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MSI-H"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26203-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#549

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1022
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:34 GMT
last-modified:Fri, 19 Dec 2025 22:16:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943720

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#85147-7 (\"PD-L1 by clone 22C3 in Tissue by Immune stain Report\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#85147-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#550

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2190
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:35 GMT
last-modified:Fri, 19 Dec 2025 22:16:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943721

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26203-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1971-2\": Code \"LA26203-2\" not found in http://loinc.org|2.81\r\n"}]}

#551

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2194
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:35 GMT
last-modified:Fri, 19 Dec 2025 22:16:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943722

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA6576-8\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1971-2\": Code \"LA6576-8\" not found in http://loinc.org|2.81\r\n"}]}

#552

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 19 Dec 2025 22:16:36 GMT
last-modified:Fri, 19 Dec 2025 22:16:36 GMT
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x-request-id:252-943723

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA26203-2\"\r\n"}]}

#553

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-cibuild","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:36 GMT
last-modified:Fri, 19 Dec 2025 22:16:36 GMT
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x-request-id:252-943724

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-cibuild\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#LA6576-8\"\r\n"}]}

#554

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 19 Dec 2025 22:16:37 GMT
last-modified:Fri, 19 Dec 2025 22:16:37 GMT
pragma:no-cache
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x-request-id:252-943725

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1040-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1040-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26806-2\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1040-6) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1040-6\": Code \"LA26806-2\" found in http://loinc.org|2.81\r\n"}]}

#555

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"309529002","display":"Lung mass (finding)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1059
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:37 GMT
last-modified:Fri, 19 Dec 2025 22:16:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-943726

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "309529002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Lung mass"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "309529002","display" : "Lung mass (finding)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#309529002 (\"Lung mass (finding)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#309529002\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#556

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"424993006","display":"Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:37 GMT
last-modified:Fri, 19 Dec 2025 22:16:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-943727

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "424993006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Adenocarcinoma of lung, stage IV"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "424993006","display" : "Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#424993006 (\"Adenocarcinoma of lung, stage IV (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#424993006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#557

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:959
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:38 GMT
last-modified:Fri, 19 Dec 2025 22:16:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-943728

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#558

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic State"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:905
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:39 GMT
last-modified:Fri, 19 Dec 2025 22:16:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943729

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic State"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"Allelic State\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#559

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5","display":"Genomic allele start-end"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:938
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:39 GMT
last-modified:Fri, 19 Dec 2025 22:16:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943730

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5","display" : "Genomic allele start-end"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"Genomic allele start-end\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#560

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"398036000","display":"Familial hypercholesterolemia (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1132
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:39 GMT
last-modified:Fri, 19 Dec 2025 22:16:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-943732

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "398036000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Familial hypercholesterolemia (disorder)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "398036000","display" : "Familial hypercholesterolemia (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#398036000 (\"Familial hypercholesterolemia (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#398036000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#561

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5489-1","name":"LOINCAnswersLL5489-1","title":"LOINC Answer Codes for LL5489-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1178
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:40 GMT
last-modified:Fri, 19 Dec 2025 22:16:40 GMT
pragma:no-cache
server:nginx
x-request-id:252-943733

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5489-1 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5489-1)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26320-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5489-1) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL5489-1\": Code \"LA26320-4\" found in http://loinc.org|2.81\r\n"}]}

#562

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:898
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:41 GMT
last-modified:Fri, 19 Dec 2025 22:16:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-943734

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26320-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#563

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1205
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:41 GMT
last-modified:Fri, 19 Dec 2025 22:16:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-943736

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26426-9\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4050-2\": Code \"LA26426-9\" found in http://loinc.org|2.81\r\n"}]}

#564

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:925
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:41 GMT
last-modified:Fri, 19 Dec 2025 22:16:41 GMT
pragma:no-cache
server:nginx
x-request-id:252-943737

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26426-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#565

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"18474-7","display":"HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:42 GMT
last-modified:Fri, 19 Dec 2025 22:16:42 GMT
pragma:no-cache
server:nginx
x-request-id:252-943738

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "18474-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 Ag [Presence] in Tissue by Immune stain"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "18474-7","display" : "HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#18474-7 (\"HER2 Ag [Presence] in Tissue by Immune stain\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#18474-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#566

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:998
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:43 GMT
last-modified:Fri, 19 Dec 2025 22:16:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-943740

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "72382-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#72382-5 (\"HER2 [Units/volume] in Tissue by Immunoassay\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#72382-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#567

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7","display":"Variant ISCN"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:43 GMT
last-modified:Fri, 19 Dec 2025 22:16:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-943744

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7","display" : "Variant ISCN"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"Variant ISCN\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#568

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1483
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:43 GMT
last-modified:Fri, 19 Dec 2025 22:16:43 GMT
pragma:no-cache
server:nginx
x-request-id:252-943747

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX,t(9;22)(q34;q4)"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[https://iscn.karger.com#46,XX,t(9;22)(q34;q4) (\"\")]\"\r\n0 0     : 0ms  : Check \"https://iscn.karger.com#46,XX,t(9;22)(q34;q4)\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}

#569

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"92818009","display":"Chronic myeloid leukemia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1080
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:44 GMT
last-modified:Fri, 19 Dec 2025 22:16:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-943749

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "92818009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Chronic myeloid leukemia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "92818009","display" : "Chronic myeloid leukemia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#92818009 (\"Chronic myeloid leukemia\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#92818009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#570

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2","display":"Cytogenetic (chromosome) location"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:965
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:44 GMT
last-modified:Fri, 19 Dec 2025 22:16:44 GMT
pragma:no-cache
server:nginx
x-request-id:252-943752

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2","display" : "Cytogenetic (chromosome) location"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"Cytogenetic (chromosome) location\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#571

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]","display":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1010
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:45 GMT
last-modified:Fri, 19 Dec 2025 22:16:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943755

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#572

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1292
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:45 GMT
last-modified:Fri, 19 Dec 2025 22:16:45 GMT
pragma:no-cache
server:nginx
x-request-id:252-943757

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#573

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"44054006","display":"Diabetes mellitus type 2 (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1103
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:46 GMT
last-modified:Fri, 19 Dec 2025 22:16:46 GMT
pragma:no-cache
server:nginx
x-request-id:252-943763

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "44054006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Diabetes mellitus type II"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "44054006","display" : "Diabetes mellitus type 2 (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#44054006 (\"Diabetes mellitus type 2 (disorder)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#44054006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#574

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]","display":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:850
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:47 GMT
last-modified:Fri, 19 Dec 2025 22:16:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943765

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"NM_004643.3:c.3GGC[14]\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#575

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1131
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:47 GMT
last-modified:Fri, 19 Dec 2025 22:16:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943766

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NM_004643.3:c.3GGC[14]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#576

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:47 GMT
last-modified:Fri, 19 Dec 2025 22:16:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943768

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#577

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1112
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:47 GMT
last-modified:Fri, 19 Dec 2025 22:16:47 GMT
pragma:no-cache
server:nginx
x-request-id:252-943770

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_000044.6:c.7G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#578

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met","display":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:845
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:48 GMT
last-modified:Fri, 19 Dec 2025 22:16:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-943771

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"NP_000035.2:p.Val3Met\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#579

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1126
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:48 GMT
last-modified:Fri, 19 Dec 2025 22:16:48 GMT
pragma:no-cache
server:nginx
x-request-id:252-943773

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NP_000035.2:p.Val3Met\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#580

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A","display":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:49 GMT
last-modified:Fri, 19 Dec 2025 22:16:49 GMT
pragma:no-cache
server:nginx
x-request-id:252-943776

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"NC_000019.8:g.1171707G>A\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#581

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1142
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:49 GMT
last-modified:Fri, 19 Dec 2025 22:16:49 GMT
pragma:no-cache
server:nginx
x-request-id:252-943778

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NC_000019.8:g.1171707G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#582

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1963
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:49 GMT
last-modified:Fri, 19 Dec 2025 22:16:49 GMT
pragma:no-cache
server:nginx
x-request-id:252-943781

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n16 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0    : 0ms  : Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n16 0    : 0ms  : Check \"http://snomed.info/sct#444734003\"\r\n31 15   : 15ms : CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n31 0    : 15ms : check code in (http://snomed.info/sct)(444734003,399223003) at CodeableConcept.coding[0]\r\n31 0    : 15ms : Code \"444734003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}

#583

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1181
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:49 GMT
last-modified:Fri, 19 Dec 2025 22:16:49 GMT
pragma:no-cache
server:nginx
x-request-id:252-943783

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#444734003\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#584

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive (qualifier value)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-interpretation","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/observation-interpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.399"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.386"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.218"}],"version":"6.0.0-ballot3","name":"ObservationInterpretationCodes","title":"Observation Interpretation Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"A categorical assessment, providing a rough qualitative interpretation of the observation value,    such as “normal”/ “abnormal”,”low” / “high”, “better” / “worse”, “susceptible” / “resistant”, “expected”/ “not expected”.    The value set is intended to be for ANY use where coded representation of an interpretation is needed.   \r\n   \r\n   Notes:\r\n   \r\n   This is being communicated in v2.x in OBX-8 (Observation Interpretation), in v3 in ObservationInterpretation (CWE) in R1 (Representative Realm) and in FHIR in    Observation.interpretation. Historically these values come from the laboratory domain, and these codes are extensively    used. The value set binding is extensible, so codes outside the value set that are needed for interpretation concepts    (i.e. particular meanings) that are not included in the value set can be used, and these new codes may also be added to    the value set and published in a future version.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"v3-ObservationInterpretation","language":"en","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"url":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.5.83"}],"version":"3.0.0","name":"ObservationInterpretation","title":"ObservationInterpretation","status":"active","experimental":false,"date":"2019-03-20","publisher":"Health Level Seven International","contact":[{"telecom":[{"system":"url","value":"http://hl7.org"},{"system":"email","value":"hq@HL7.org"}]}],"description":"One or more codes providing a rough qualitative interpretation of the observation, such as \"normal\" / \"abnormal\", \"low\" / \"high\", \"better\" / \"worse\", \"resistant\" / \"susceptible\", \"expected\" / \"not expected\". The value set is intended to be for ANY use where coded representation of an interpretation is needed.","copyright":"This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html","caseSensitive":true,"hierarchyMeaning":"is-a","content":"complete","property":[{"code":"internalId","uri":"http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id","description":"The internal identifier for the concept in the HL7 Access database repository.","type":"code"},{"code":"notSelectable","uri":"http://hl7.org/fhir/concept-properties#notSelectable","description":"Indicates that the code is abstract - only intended to be used as a selector for other concepts","type":"boolean"},{"code":"status","uri":"http://hl7.org/fhir/concept-properties#status","description":"A property that indicates the status of the concept. One of active, experimental, deprecated, or retired.","type":"code"},{"code":"deprecationDate","uri":"http://hl7.org/fhir/concept-properties#deprecationDate","description":"The date at which a concept was deprecated. Concepts that are deprecated but not inactive can still be used, but their use is discouraged.","type":"dateTime"},{"code":"subsumedBy","uri":"http://hl7.org/fhir/concept-properties#parent","description":"The concept code of a parent concept","type":"code"}],"concept":[{"code":"_GeneticObservationInterpretation","display":"GeneticObservationInterpretation","definition":"Codes that specify interpretation of genetic analysis, such as \"positive\", \"negative\", \"carrier\", \"responsive\", etc.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22646"}]},{"code":"_ObservationInterpretationChange","display":"ObservationInterpretationChange","definition":"Interpretations of change of quantity and/or severity. At most one of B or W and one of U or D allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21090"}]},{"code":"_ObservationInterpretationExceptions","display":"ObservationInterpretationExceptions","definition":"Technical exceptions resulting in the inability to provide an interpretation. At most one allowed. Does not imply normality or severity.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21091"}]},{"code":"_ObservationInterpretationNormality","display":"ObservationInterpretationNormality","definition":"Interpretation of normality or degree of abnormality (including critical or \"alert\" level). Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21092"}]},{"code":"_ObservationInterpretationSusceptibility","display":"ObservationInterpretationSusceptibility","definition":"Interpretations of anti-microbial susceptibility testing results (microbiology). At most one allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21093"}]},{"code":"EX","display":"outside threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21634"}]},{"code":"HM","display":"Hold for Medical Review","definition":"Hold for Medical Review\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23790"}]},{"code":"ObservationInterpretationDetection","display":"ObservationInterpretationDetection","definition":"Interpretations of the presence or absence of a component / analyte or organism in a test or of a sign in a clinical observation. In keeping with laboratory data processing practice, these concepts provide a categorical interpretation of the \"meaning\" of the quantitative value for the same observation.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22805"}]},{"code":"ObservationInterpretationExpectation","display":"ObservationInterpretationExpectation","definition":"Interpretation of the observed result taking into account additional information (contraindicators) about the patient's situation. Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23723"}]},{"code":"OBX","display":"Interpretation qualifiers in separate OBX segments","definition":"Interpretation qualifiers in separate OBX segments\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23789"}]},{"code":"ReactivityObservationInterpretation","display":"ReactivityObservationInterpretation","definition":"Interpretations of the presence and level of reactivity of the specified component / analyte with the reagent in the performed laboratory test.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23568"}]},{"code":"CAR","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23559"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"Carrier","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This code is currently the same string as the print name for this concept and is inconsistent with the conventions being used for the other codes in the coding system, as it is a full word with initial capitalization, rather than an all upper case mnemonic. The recommendation from OO is to deprecate the code \"Carrier\" and to add \"CAR\" as the new active code representation for this concept.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"22647"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"B","display":"Better","definition":"The current result or observation value has improved compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10215"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"D","display":"Significant change down","definition":"The current result has decreased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10218"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"U","display":"Significant change up","definition":"The current result has increased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10217"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"W","display":"Worse","definition":"The current result or observation value has degraded compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10216"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"<","display":"Off scale low","definition":"The result is below the minimum detection limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Below analytical limit, low off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10226"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":">","display":"Off scale high","definition":"The result is above the maximum quantifiable limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Above analytical limit, high off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10227"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"AC","display":"Anti-complementary substances present","definition":"A valid result cannot be obtained for the specified component / analyte due to the presence of anti-complementary substances in the sample.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23564"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"IE","display":"Insufficient evidence","definition":"There is insufficient evidence that the species in question is a good target for therapy with the drug. A categorical interpretation is not possible.\r\n\r\n\\[Note: A MIC with \"IE\" and/or a comment may be reported (without an accompanying S, I or R-categorization).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23567"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"QCF","display":"Quality control failure","definition":"A result cannot be considered valid for the specified component / analyte or organism due to failure in the quality control testing component.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23565"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"TOX","display":"Cytotoxic substance present","definition":"A valid result cannot be obtained for the specified organism or cell line due to the presence of cytotoxic substances in the sample or culture.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23566"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"A","display":"Abnormal","definition":"The result or observation value is outside the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10208"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"N","display":"Normal","definition":"The result or observation value is within the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Applies to numeric or non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10207"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"I","display":"Intermediate","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\\]\r\n\r\n\\[Note 3: This class also indicates a \"buffer zone,\" to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\\]\r\n\r\n\\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10221"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"MS","display":"moderately susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10222"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NCL","display":"No CLSI defined breakpoint","definition":"Use when not enough clinical trial data published by the Clinical and Laboratory Standards Institutes (CLSI) is available to establish the breakpoints for susceptible / intermediate and resistant.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23886"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NS","display":"Non-susceptible","definition":"A category used for isolates for which only a susceptible interpretive criterion has been designated because of the absence or rare occurrence of resistant strains. Isolates that have MICs above or zone diameters below the value indicated for the susceptible breakpoint should be reported as non-susceptible.\r\n\r\nNOTE 1: An isolate that is interpreted as non-susceptible does not necessarily mean that the isolate has a resistance mechanism. It is possible that isolates with MICs above the susceptible breakpoint that lack resistance mechanisms may be encountered within the wild-type distribution subsequent to the time the susceptible-only breakpoint is set.\r\n\r\nNOTE 2: For strains yielding results in the \"nonsusceptible\" category, organism identification and antimicrobial susceptibility test results should be confirmed.\r\n\r\nSynonym: decreased susceptibility.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23557"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"R","display":"Resistant","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic failure. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as resistant by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10220"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"S","display":"Susceptible","definition":"Bacterial strain inhibited by in vitro concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic success. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Synonym (earlier term): Sensitive Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as susceptible by applying the appropriate breakpoints in a defined phenotypic system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10223"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"VS","display":"very susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10224"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"AA","display":"Critical abnormal","definition":"The result or observation value is outside a reference range or expected norm at a level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results. Analogous to critical/panic limits for numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10211"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"H","display":"High","definition":"The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Above high normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10210"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"L","display":"Low","definition":"The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Below low normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10209"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"HH","display":"Critical high","definition":"The result for a quantitative observation is above a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Above upper panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10213"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"H>"},{"code":"subsumedBy","valueCode":"HU"}]},{"code":"LL","display":"Critical low","definition":"The result for a quantitative observation is below a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Below lower panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10212"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"L<"},{"code":"subsumedBy","valueCode":"LU"}]},{"code":"HX","display":"above high threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21636"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"LX","display":"below low threshold","definition":"The numeric observation/test result is interpreted as being below the low threshold value for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A Total White Blood Cell Count falling below a protocol-defined threshold value of 3000/mm^3\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21635"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"H>","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'H' and 'HH'.\\]\r\n\r\n*Deprecation Comment:* The code 'H>' is being deprecated in order to align with the use of the code 'HU' for \"Very high\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'H>' is non-preferred, as this code is deprecated and on track to be retired; use code 'HU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23560"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"HU","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23742"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"E","display":"Equivocal","definition":"The test or procedure was successfully performed, but the results are borderline and can neither be declared positive / negative nor detected / not detected according to the current established criteria.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23732"},{"code":"subsumedBy","valueCode":"IND"}]},{"code":"L<","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'L' and 'LL'.\\]\r\n\r\n*Deprecation Comment:* The code 'L<' is being deprecated in order to align with the use of the code 'LU' for \"Very low\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'L<' is non-preferred, as this code is deprecated and on track to be retired; use code 'LU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23561"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"LU","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23743"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"ND","display":"Not detected","definition":"The presence of the specified component / analyte, organism or clinical sign could not be determined within the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23563"},{"code":"subsumedBy","valueCode":"NEG"}]},{"code":"IND","display":"Indeterminate","definition":"The specified component / analyte, organism or clinical sign could neither be declared positive / negative nor detected / not detected by the performed test or procedure.\r\n\r\n*Usage Note:* For example, if the specimen was degraded, poorly processed, or was missing the required anatomic structures, then \"indeterminate\" (i.e. \"cannot be determined\") is the appropriate response, not \"equivocal\".","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22807"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"NEG","display":"Negative","definition":"An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.\r\n\r\n\\[Note: Negative does not necessarily imply the complete absence of the specified item.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22808"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"POS","display":"Positive","definition":"A presence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22806"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"EXP","display":"Expected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Expected\" (e.g., presence of drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23724"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"UNE","display":"Unexpected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Unexpected\" (e.g., presence of non-prescribed drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23725"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"DET","display":"Detected","definition":"The measurement of the specified component / analyte, organism or clinical sign above the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23562"},{"code":"subsumedBy","valueCode":"POS"}]},{"code":"SYN-R","display":"Synergy - resistant","definition":"A category for isolates where the bacteria (e.g. enterococci) are not susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will not be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23621"},{"code":"subsumedBy","valueCode":"R"}]},{"code":"NR","display":"Non-reactive","definition":"An absence finding used to indicate that the specified component / analyte did not react measurably with the reagent.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23569"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"RR","display":"Reactive","definition":"A presence finding used to indicate that the specified component / analyte reacted with the reagent above the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23570"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"WR","display":"Weakly reactive","definition":"A weighted presence finding used to indicate that the specified component / analyte reacted with the reagent, but below the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23571"},{"code":"subsumedBy","valueCode":"RR"}]},{"code":"SDD","display":"Susceptible-dose dependent","definition":"A category that includes isolates with antimicrobial agent minimum inhibitory concentrations (MICs) that approach usually attainable blood and tissue levels and for which response rates may be lower than for susceptible isolates.\r\n\r\nReference: CLSI document M44-A2 2009 \"Method for antifungal disk diffusion susceptibility testing of yeasts; approved guideline - second edition\" - page 2.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23558"},{"code":"subsumedBy","valueCode":"S"}]},{"code":"SYN-S","display":"Synergy - susceptible","definition":"A category for isolates where the bacteria (e.g. enterococci) are susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23620"},{"code":"subsumedBy","valueCode":"S"}]}]}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "10828004","display" : "Positive (qualifier value)"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://snomed.info/sct#10828004 ('Positive (qualifier value)')' was not found in the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n63 63   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3 for validation purposes\r\n63 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n63 0    : 0ms  : Prepare include: \"(http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation)\"\r\n63 0    : 0ms  : CodeSystem found: \"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation|3.0.0\"\r\n63 0    : 0ms  : Validate \"[http://snomed.info/sct#10828004 (\"Positive (qualifier value)\")]\"\r\n63 0    : 0ms  : Check \"http://snomed.info/sct#10828004\"\r\n"}]}

#585

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G","display":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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last-modified:Fri, 19 Dec 2025 22:16:50 GMT
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"NC_000010.11:g.121498525T>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#586

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n93 93   : 93ms : Code \"NC_000010.11:g.121498525T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#587

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-cibuild","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-cibuild for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"(http://loinc.org)(LA10315-2,LA25391-6,LA25390-8,LA10317-8,LA9657-3,LA19542-2,LA19541-4,LA6676-6,LA6677-4,LA9660-7,LA9661-5,LA6682-4,LA6675-8,LA6674-1,LA9662-3,LA25392-4,LA25393-2,LA25395-7,LA25394-0)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0    : 0ms  : Prepare include: \"(http://snomed.info/sct)(444734003,399223003)\"\r\n15 0    : 0ms  : CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0    : 0ms  : Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n15 0    : 0ms  : Check \"http://snomed.info/sct#399223003\"\r\n15 0    : 0ms  : CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n15 0    : 0ms  : check code in (http://snomed.info/sct)(444734003,399223003) at CodeableConcept.coding[0]\r\n15 0    : 0ms  : Code \"399223003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}

#588

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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date:Fri, 19 Dec 2025 22:16:50 GMT
last-modified:Fri, 19 Dec 2025 22:16:50 GMT
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server:nginx
x-request-id:252-943791

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#399223003\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#589

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254837009","display":"Breast Cancer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1063
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:51 GMT
last-modified:Fri, 19 Dec 2025 22:16:51 GMT
pragma:no-cache
server:nginx
x-request-id:252-943793

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254837009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant tumor of breast"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254837009","display" : "Breast Cancer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://snomed.info/sct#254837009 (\"Breast Cancer\")]\"\r\n16 0    : 0ms  : Check \"http://snomed.info/sct#254837009\"\r\n16 0    : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#590

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1164
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:53 GMT
last-modified:Fri, 19 Dec 2025 22:16:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943805

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}

#591

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:884
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:53 GMT
last-modified:Fri, 19 Dec 2025 22:16:53 GMT
pragma:no-cache
server:nginx
x-request-id:252-943807

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#592

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1163
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:54 GMT
last-modified:Fri, 19 Dec 2025 22:16:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943811

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4048-6 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4048-6)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26418-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4048-6) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4048-6\": Code \"LA26418-6\" found in http://loinc.org|2.81\r\n"}]}

#593

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:883
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:54 GMT
last-modified:Fri, 19 Dec 2025 22:16:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943813

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26418-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#594

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2184
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:54 GMT
last-modified:Fri, 19 Dec 2025 22:16:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943817

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26418-6 ('PCR')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4050-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4050-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26418-6\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4050-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL4050-2\": Code \"LA26418-6\" not found in http://loinc.org|2.81\r\n"}]}

#595

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"5262007","display":"Spinal muscular atrophy (disorder)"}],"text":"Spinal muscular atrophy (SMA)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1136
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:55 GMT
last-modified:Fri, 19 Dec 2025 22:16:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-943819

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "5262007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Spinal muscular atrophy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "5262007","display" : "Spinal muscular atrophy (disorder)"}],"text" : "Spinal muscular atrophy (SMA)"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://snomed.info/sct#5262007 (\"Spinal muscular atrophy (disorder)\")]\"\r\n16 0    : 0ms  : Check \"http://snomed.info/sct#5262007\"\r\n16 0    : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#596

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000001.10:g.86852621A>G","display":"NC_000001.10:g.86852621A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:870
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:55 GMT
last-modified:Fri, 19 Dec 2025 22:16:55 GMT
pragma:no-cache
server:nginx
x-request-id:252-943821

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000001.10:g.86852621A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000001.10:g.86852621A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G (\"NC_000001.10:g.86852621A>G\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#597

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic Ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:56 GMT
last-modified:Fri, 19 Dec 2025 22:16:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-943823

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic Ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"Genomic Ref allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#598

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic Alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:935
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:56 GMT
last-modified:Fri, 19 Dec 2025 22:16:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-943826

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic Alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69551-0 (\"Genomic Alt allele [ID]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69551-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#599

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1229
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:56 GMT
last-modified:Fri, 19 Dec 2025 22:16:56 GMT
pragma:no-cache
server:nginx
x-request-id:252-943828

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL5323-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL5323-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL5323-2) at CodeableConcept.coding[0]\r\n16 16   : 16ms : Filter \"LIST=LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}

#600

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:949
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:57 GMT
last-modified:Fri, 19 Dec 2025 22:16:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943830

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA30100-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#601

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Variant exact start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:910
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:57 GMT
last-modified:Fri, 19 Dec 2025 22:16:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943831

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Variant exact start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#602

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}],"text":"Population allele frequency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:921
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:58 GMT
last-modified:Fri, 19 Dec 2025 22:16:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-943834

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}],"text" : "Population allele frequency"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#603

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction","code":"HIGH","display":"High"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1821
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:58 GMT
last-modified:Fri, 19 Dec 2025 22:16:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-943838

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "code","valueCode" : "HIGH"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH (\"High\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction\"\r\n"}]}

#604

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C","display":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:850
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:58 GMT
last-modified:Fri, 19 Dec 2025 22:16:58 GMT
pragma:no-cache
server:nginx
x-request-id:252-943839

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"NM_001366781.1:c.90T>C\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#605

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1132
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:59 GMT
last-modified:Fri, 19 Dec 2025 22:16:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-943842

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n109 109 : 109ms : Code \"NM_001366781.1:c.90T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#606

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C","display":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:860
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:59 GMT
last-modified:Fri, 19 Dec 2025 22:16:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-943844

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"NM_001395543.1:c.-171T>C\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n0 0     : 0ms  : Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}

#607

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-cibuild","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1141
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:16:59 GMT
last-modified:Fri, 19 Dec 2025 22:16:59 GMT
pragma:no-cache
server:nginx
x-request-id:252-943846

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-cibuild for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://varnomen.hgvs.org)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0     : 0ms  : Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"\")]\"\r\n0 0     : 0ms  : Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n0 0     : 0ms  : CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n0 0     : 0ms  : check code in (http://varnomen.hgvs.org) at Coding\r\n94 94   : 94ms : Code \"NM_001395543.1:c.-171T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}

#608

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1565
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:00 GMT
last-modified:Fri, 19 Dec 2025 22:17:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-943849

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"Autosomal recessive inheritance\")]\"\r\n0 0     : 0ms  : Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://human-phenotype-ontology.org\"\r\n"}]}

#609

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8","display":"Allelic frequency in Population"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:959
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:00 GMT
last-modified:Fri, 19 Dec 2025 22:17:00 GMT
pragma:no-cache
server:nginx
x-request-id:252-943850

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8","display" : "Allelic frequency in Population"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"Allelic frequency in Population\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#610

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:892
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:01 GMT
last-modified:Fri, 19 Dec 2025 22:17:01 GMT
pragma:no-cache
server:nginx
x-request-id:252-943855

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26806-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#611

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8"}],"text":"Genetic variation clinical significance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:02 GMT
last-modified:Fri, 19 Dec 2025 22:17:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-943859

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}],"text" : "Genetic variation clinical significance"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#612

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4"}],"text":"Predicted phenotype"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:02 GMT
last-modified:Fri, 19 Dec 2025 22:17:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-943861

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}],"text" : "Predicted phenotype"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81259-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#613

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405501007","display":"Malignant hyperthermia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1078
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:02 GMT
last-modified:Fri, 19 Dec 2025 22:17:02 GMT
pragma:no-cache
server:nginx
x-request-id:252-943865

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405501007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant hyperthermia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405501007","display" : "Malignant hyperthermia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#405501007 (\"Malignant hyperthermia\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#405501007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#614

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:947
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:03 GMT
last-modified:Fri, 19 Dec 2025 22:17:03 GMT
pragma:no-cache
server:nginx
x-request-id:252-943866

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#48002-0 (\"Genomic source class [Type]\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#48002-0\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#615

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Genomic allele start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:04 GMT
last-modified:Fri, 19 Dec 2025 22:17:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-943867

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Genomic allele start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#616

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39","display":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1858
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:04 GMT
last-modified:Fri, 19 Dec 2025 22:17:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-943870

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39 (\"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\")]\"\r\n0 0     : 0ms  : Check \"http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}

#617

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:891
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:04 GMT
last-modified:Fri, 19 Dec 2025 22:17:04 GMT
pragma:no-cache
server:nginx
x-request-id:252-943871

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#618

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA Change Type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:911
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:05 GMT
last-modified:Fri, 19 Dec 2025 22:17:05 GMT
pragma:no-cache
server:nginx
x-request-id:252-943873

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA Change Type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"DNA Change Type\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#619

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic Source Class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:933
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:05 GMT
last-modified:Fri, 19 Dec 2025 22:17:05 GMT
pragma:no-cache
server:nginx
x-request-id:252-943875

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic Source Class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"Genomic Source Class\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#620

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}],"text":"Variant inner start and end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:928
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:06 GMT
last-modified:Fri, 19 Dec 2025 22:17:06 GMT
pragma:no-cache
server:nginx
x-request-id:252-943876

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}],"text" : "Variant inner start and end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#621

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1170
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:06 GMT
last-modified:Fri, 19 Dec 2025 22:17:06 GMT
pragma:no-cache
server:nginx
x-request-id:252-943877

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1971-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1971-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA9633-4\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1971-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}

#622

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3","display":"Genomic Structural Variant copy Number"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:980
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:07 GMT
last-modified:Fri, 19 Dec 2025 22:17:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-943878

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3","display" : "Genomic Structural Variant copy Number"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n15 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n15 0    : 0ms  : Prepare include: \"()\"\r\n15 0    : 0ms  : Validate \"[http://loinc.org#82155-3 (\"Genomic Structural Variant copy Number\")]\"\r\n15 0    : 0ms  : Check \"http://loinc.org#82155-3\"\r\n15 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#623

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"480167","display":"Lapatinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1020
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:07 GMT
last-modified:Fri, 19 Dec 2025 22:17:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-943879

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "480167"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "lapatinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "480167","display" : "Lapatinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#480167 (\"Lapatinib\")]\"\r\n0 0     : 0ms  : Check \"http://www.nlm.nih.gov/research/umls/rxnorm#480167\"\r\n0 0     : 0ms  : Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}

#624

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"443968007","display":"Sequencing of entire coding region of gene (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1174
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:07 GMT
last-modified:Fri, 19 Dec 2025 22:17:07 GMT
pragma:no-cache
server:nginx
x-request-id:252-943880

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "443968007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Sequencing of entire coding region of gene (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "443968007","display" : "Sequencing of entire coding region of gene (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://snomed.info/sct#443968007 (\"Sequencing of entire coding region of gene (procedure)\")]\"\r\n16 0    : 0ms  : Check \"http://snomed.info/sct#443968007\"\r\n16 0    : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#625

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"a"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:08 GMT
last-modified:Fri, 19 Dec 2025 22:17:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943881

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "a"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "a"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://unitsofmeasure.org#a (\"\")]\"\r\n0 0     : 0ms  : Check \"http://unitsofmeasure.org#a\"\r\n0 0     : 0ms  : Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}

#626

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94231-8","display":"G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1061
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:08 GMT
last-modified:Fri, 19 Dec 2025 22:17:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943882

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94231-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94231-8","display" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94231-8 (\"G6PD gene full mutation analysis in Blood or Tissue by Sequencing\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94231-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#627

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1642
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:08 GMT
last-modified:Fri, 19 Dec 2025 22:17:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943884

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0     : 0ms  : Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0     : 0ms  : Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}

#628

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405825005","display":"Molecular genetic test (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1114
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:08 GMT
last-modified:Fri, 19 Dec 2025 22:17:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943886

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405825005"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Molecular genetic test (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405825005","display" : "Molecular genetic test (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#405825005 (\"Molecular genetic test (procedure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#405825005\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#629

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"108252007","display":"Laboratory procedure"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1072
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:08 GMT
last-modified:Fri, 19 Dec 2025 22:17:08 GMT
pragma:no-cache
server:nginx
x-request-id:252-943887

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "108252007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Laboratory procedure"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "108252007","display" : "Laboratory procedure"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#108252007 (\"Laboratory procedure\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#108252007\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#630

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13298-5","display":"HLA-A [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:902
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:09 GMT
last-modified:Fri, 19 Dec 2025 22:17:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-943888

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13298-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13298-5","display" : "HLA-A [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#13298-5 (\"HLA-A [Type]\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#13298-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#631

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"258564008","display":"Buccal smear sample"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1069
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:09 GMT
last-modified:Fri, 19 Dec 2025 22:17:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-943892

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "258564008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal smear sample"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "258564008","display" : "Buccal smear sample"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#258564008 (\"Buccal smear sample\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#258564008\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#632

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122610009","display":"Specimen from lung obtained by biopsy (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1145
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:09 GMT
last-modified:Fri, 19 Dec 2025 22:17:09 GMT
pragma:no-cache
server:nginx
x-request-id:252-943894

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122610009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Specimen from lung obtained by biopsy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122610009","display" : "Specimen from lung obtained by biopsy (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#122610009 (\"Specimen from lung obtained by biopsy (specimen)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#122610009\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#633

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"129314006","display":"Biopsy - action"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1057
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:10 GMT
last-modified:Fri, 19 Dec 2025 22:17:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943896

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "129314006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Biopsy - action"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "129314006","display" : "Biopsy - action"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#129314006 (\"Biopsy - action\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#129314006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#634

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"119297000","display":"Blood specimen (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1076
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:10 GMT
last-modified:Fri, 19 Dec 2025 22:17:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943897

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "119297000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "119297000","display" : "Blood specimen (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#119297000 (\"Blood specimen (specimen)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#119297000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#635

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"418622002","display":"Taking oral swab (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1096
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:10 GMT
last-modified:Fri, 19 Dec 2025 22:17:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943899

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "418622002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Taking oral swab (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "418622002","display" : "Taking oral swab (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#418622002 (\"Taking oral swab (procedure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#418622002\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#636

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"261063000","display":"Buccal space"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1048
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:10 GMT
last-modified:Fri, 19 Dec 2025 22:17:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943901

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "261063000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal space"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "261063000","display" : "Buccal space"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#261063000 (\"Buccal space\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#261063000\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#637

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"3341006","display":"Right lung structure (body structure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
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content-length:1088
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:10 GMT
last-modified:Fri, 19 Dec 2025 22:17:10 GMT
pragma:no-cache
server:nginx
x-request-id:252-943903

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "3341006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Right lung"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "3341006","display" : "Right lung structure (body structure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://snomed.info/sct#3341006 (\"Right lung structure (body structure)\")]\"\r\n0 0     : 0ms  : Check \"http://snomed.info/sct#3341006\"\r\n0 0     : 0ms  : Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}

#638

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1170
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:11 GMT
last-modified:Fri, 19 Dec 2025 22:17:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943904

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL4049-4 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL4049-4)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26421-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL4049-4) at CodeableConcept.coding[0]\r\n15 15   : 15ms : Filter \"LIST=LL4049-4\": Code \"LA26421-0\" found in http://loinc.org|2.81\r\n"}]}

#639

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0","display":"Consider alternative medication"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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cache-control:public, max-age=600
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:11 GMT
last-modified:Fri, 19 Dec 2025 22:17:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943906

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0","display" : "Consider alternative medication"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26421-0 ('Consider alternative medication')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26421-0 (\"Consider alternative medication\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26421-0\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n16 16   : 16ms : Filter \"LIST=LL1037-2\": Code \"LA26421-0\" not found in http://loinc.org|2.81\r\n"}]}

#640

POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26422-8","display":"Decrease dose"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:11 GMT
last-modified:Fri, 19 Dec 2025 22:17:11 GMT
pragma:no-cache
server:nginx
x-request-id:252-943908

{"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26422-8","display" : "Decrease dose"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26422-8 ('Decrease dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://loinc.org/vs/LL1037-2 for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"(http://loinc.org)(LIST=LL1037-2)\"\r\n0 0     : 0ms  : CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#LA26422-8 (\"Decrease dose\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#LA26422-8\"\r\n0 0     : 0ms  : CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0     : 0ms  : check code in (http://loinc.org)(LIST=LL1037-2) at CodeableConcept.coding[0]\r\n0 0     : 0ms  : Filter \"LIST=LL1037-2\": Code \"LA26422-8\" not found in http://loinc.org|2.81\r\n"}]}

#641

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/CodeSystem/medicationknowledge-status","code":"active"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:930
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:32 GMT
last-modified:Fri, 19 Dec 2025 22:17:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943912

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/CodeSystem/medicationknowledge-status"},{"name" : "code","valueCode" : "active"},{"name" : "version","valueString" : "5.0.0"},{"name" : "display","valueString" : "Active"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active (\"\")]\"\r\n0 0     : 0ms  : Check \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active\"\r\n0 0     : 0ms  : Using CodeSystem \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status|5.0.0 (from hl7.fhir.r5.core#5.0.0)\" (content = complete)\r\n"}]}

#642

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org"}]}}}]}

422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:474
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:52 GMT
server:nginx
x-request-id:252-943914

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The value set '' expansion has too many codes to display (&gt;10000)</p></div>"},"issue" : [{"severity" : "error","code" : "too-costly","details" : {"text" : "The value set '' expansion has too many codes to display (>10000)"},"diagnostics" : "0 0 : start\r\n0 0     : not in cache\r\n0 0     : 0ms start working\r\n0 0     : 0ms compose #1\r\n"}]}

#643

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"draft"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1}],"url":"http://hl7.org/fhir/ValueSet/observation-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.396"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.383"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.216"}],"version":"6.0.0-ballot3","name":"LOINCCodes","title":"LOINC Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all LOINC codes","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}}]}

200
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access-control-expose-headers:Content-Location, Location
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content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:54 GMT
last-modified:Fri, 19 Dec 2025 22:17:54 GMT
pragma:no-cache
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x-request-id:252-943915

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"Vasopressin [Moles/volume] in Plasma --13th specimen post XXX challenge"},{"system" : "http://loinc.org","code" : "100897-8","display" : "Staphylococcus aureus [Presence] in Specimen by Organism specific culture"},{"system" : "http://loinc.org","code" : "100898-6","display" : "Lipid panel - Serum or Plasma"},{"system" : "http://loinc.org","code" : "100899-4","display" : "Enterobacteriaceae.extended spectrum beta lactamase resistance phenotype [Identifier] in Specimen by Organism specific culture"}]}}

#644

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4034-6"}]}]}}}]}

200
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cache-control:public, max-age=600
connection:keep-alive
content-length:827
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:54 GMT
last-modified:Fri, 19 Dec 2025 22:17:54 GMT
pragma:no-cache
server:nginx
x-request-id:252-943916

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:479814d6-0a76-4883-96f5-aecc5f2a63e5","timestamp" : "2025-12-19T22:17:54.286Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6668-3","display" : "Pathogenic"},{"system" : "http://loinc.org","code" : "LA26332-9","display" : "Likely pathogenic"},{"system" : "http://loinc.org","code" : "LA26333-7","display" : "Uncertain significance"},{"system" : "http://loinc.org","code" : "LA26334-5","display" : "Likely benign"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"}]}}

#645

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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422
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date:Fri, 19 Dec 2025 22:17:54 GMT
server:nginx
x-request-id:252-943918

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded"}}]}

#646

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:700
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:54 GMT
server:nginx
x-request-id:252-943920

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the value set cannot be expanded"}}]}

#647

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.genenames.org"}]}}}]}

422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:678
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:56 GMT
server:nginx
x-request-id:252-943922

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.genenames.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the value set cannot be expanded"}}]}

#648

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"hgnc-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs","version":"4.0.0-cibuild","name":"HGNCVS","title":"HUGO Gene Nomenclature Committee Gene Names (HGNC)","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"This value set includes all HGNC Codes, which includes multiple code systems. In this guide, Gene IDs from HGNC are used as CodeableConcepts, which must be sent with the HGNC gene ID including the prefix 'HGNC:' as the code and the HGNC 'gene symbol' as display. CAUTION: HGNC also indexes gene groups by numeric ID (without a prefix), and older systems may send HGNC gene IDs without the prefix, so care must be taken to confirm alignment. We have separately included the genegroup code system to draw attention to this ambiguity and potential error.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.genenames.org"},{"system":"http://www.genenames.org/genegroup"}]}}}]}

422
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:678
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:56 GMT
server:nginx
x-request-id:252-943924

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.genenames.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the value set cannot be expanded"}}]}

#649

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:772
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:57 GMT
last-modified:Fri, 19 Dec 2025 22:17:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943925

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#650

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:814
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:17:57 GMT
last-modified:Fri, 19 Dec 2025 22:17:57 GMT
pragma:no-cache
server:nginx
x-request-id:252-943926

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:701ab5df-37d1-495d-a351-622d9fba0ca1","timestamp" : "2025-12-19T22:17:57.286Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA14032-9","display" : "NCBI Build 34"},{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"},{"system" : "http://loinc.org","code" : "LA14030-3","display" : "NCBI Build 36.1"},{"system" : "http://loinc.org","code" : "LA14031-1","display" : "NCBI Build 35"},{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}}

#651

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

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#652

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
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last-modified:Fri, 19 Dec 2025 22:17:59 GMT
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#653

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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#654

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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#655

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
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Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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x-request-id:252-943936

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#656

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
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server:nginx
x-request-id:252-943938

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#657

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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last-modified:Fri, 19 Dec 2025 22:18:11 GMT
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server:nginx
x-request-id:252-943939

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:36f0414e-4389-4c38-927b-07e70908992d","timestamp" : "2025-12-19T22:18:11.067Z","total" : 0,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://varnomen.hgvs.org|2.0"}]}}

#658

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
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server:nginx
x-request-id:252-943941

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#659

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"molecular-consequence-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs","version":"4.0.0-cibuild","name":"MolecularConsequenceVS","title":"Molecular Consequence Value Set","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"The calculated or observed effect of a variant on its downstream transcript and, if applicable, ensuing protein sequence.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:692
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:11 GMT
server:nginx
x-request-id:252-943943

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded"}}]}

#660

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:692
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:11 GMT
server:nginx
x-request-id:252-943945

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded"}}]}

#661

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"functional-effect-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs","version":"4.0.0-cibuild","name":"FunctionalEffectVS","title":"Functional Effect Value Set","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"The effect of a variant on downstream biological products or pathways.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:692
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:11 GMT
server:nginx
x-request-id:252-943947

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded"}}]}

#662

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2003
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:14 GMT
last-modified:Fri, 19 Dec 2025 22:18:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943948

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:31f22471-d0d3-4e99-9300-4c807ccbec6d","timestamp" : "2025-12-19T22:18:14.333Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}

#663

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:736
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:14 GMT
last-modified:Fri, 19 Dec 2025 22:18:14 GMT
pragma:no-cache
server:nginx
x-request-id:252-943949

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:a722b036-a126-4a15-bf01-9ec624392de9","timestamp" : "2025-12-19T22:18:14.426Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : true},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}

#664

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:724
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:16 GMT
last-modified:Fri, 19 Dec 2025 22:18:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943951

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:b17daa74-5b9e-49cc-aef9-e53415d573a6","timestamp" : "2025-12-19T22:18:16.270Z","total" : 4,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"},{"system" : "http://loinc.org","code" : "LA9634-2","display" : "Absent"},{"system" : "http://loinc.org","code" : "LA18198-4","display" : "No call"},{"system" : "http://loinc.org","code" : "LA11884-6","display" : "Indeterminate"}]}}

#665

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:743
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:16 GMT
last-modified:Fri, 19 Dec 2025 22:18:16 GMT
pragma:no-cache
server:nginx
x-request-id:252-943952

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#666

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:702
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:17 GMT
last-modified:Fri, 19 Dec 2025 22:18:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943955

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:7296bc22-6865-4740-827e-738d6320aa19","timestamp" : "2025-12-19T22:18:17.004Z","total" : 3,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"},{"system" : "http://loinc.org","code" : "LA30101-2","display" : "0-based character counting"},{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}}

#667

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:692
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:17 GMT
server:nginx
x-request-id:252-943957

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded"}}]}

#668

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-cibuild","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2025-12-19T22:08:31+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}

422
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
connection:keep-alive
content-length:692
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:17 GMT
server:nginx
x-request-id:252-943959

{"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded</p></div>"},"issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_EXP"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the value set cannot be expanded"}}]}

#669

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:1053
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:17 GMT
last-modified:Fri, 19 Dec 2025 22:18:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943960

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:1dcb79a5-4ed0-4ade-a41f-c44b84dab883","timestamp" : "2025-12-19T22:18:17.583Z","total" : 8,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"},{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"},{"system" : "http://loinc.org","code" : "LA10429-1","display" : "Fetal"},{"system" : "http://loinc.org","code" : "LA18194-3","display" : "Likely germline"},{"system" : "http://loinc.org","code" : "LA18195-0","display" : "Likely somatic"},{"system" : "http://loinc.org","code" : "LA18196-8","display" : "Likely fetal"},{"system" : "http://loinc.org","code" : "LA18197-6","display" : "Unknown genomic origin"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"}]}}

#670

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:812
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:17 GMT
last-modified:Fri, 19 Dec 2025 22:18:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943961

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:99c08407-ca22-498d-8648-8f2ca7ed16e6","timestamp" : "2025-12-19T22:18:17.708Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6703-8","display" : "Heteroplasmic"},{"system" : "http://loinc.org","code" : "LA6704-6","display" : "Homoplasmic"},{"system" : "http://loinc.org","code" : "LA6705-3","display" : "Homozygous"},{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"},{"system" : "http://loinc.org","code" : "LA6707-9","display" : "Hemizygous"}]}}

#671

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:798
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:17 GMT
last-modified:Fri, 19 Dec 2025 22:18:17 GMT
pragma:no-cache
server:nginx
x-request-id:252-943962

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:4a3d51b2-dfa1-465e-a1da-04d369fa988b","timestamp" : "2025-12-19T22:18:17.864Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"},{"system" : "http://loinc.org","code" : "LA26321-2","display" : "Paternal"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"},{"system" : "http://loinc.org","code" : "LA4489-6","display" : "Unknown"},{"system" : "http://loinc.org","code" : "LA30680-5","display" : "Parental"}]}}

#672

POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}}]}

200
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access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:2362
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:18 GMT
last-modified:Fri, 19 Dec 2025 22:18:18 GMT
pragma:no-cache
server:nginx
x-request-id:252-943964

{"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:8fa389bd-99f3-485d-ac85-e04569078f13","timestamp" : "2025-12-19T22:18:18.067Z","total" : 23,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"},{"system" : "http://loinc.org","code" : "LA26399-8","display" : "Oligo aCGH"},{"system" : "http://loinc.org","code" : "LA26400-4","display" : "SNP array"},{"system" : "http://loinc.org","code" : "LA26401-2","display" : "BAC aCGH"},{"system" : "http://loinc.org","code" : "LA26402-0","display" : "Curated"},{"system" : "http://loinc.org","code" : "LA26403-8","display" : "Digital array"},{"system" : "http://loinc.org","code" : "LA26404-6","display" : "FISH"},{"system" : "http://loinc.org","code" : "LA26405-3","display" : "Gene expression array"},{"system" : "http://loinc.org","code" : "LA26406-1","display" : "Karyotyping"},{"system" : "http://loinc.org","code" : "LA26407-9","display" : "MAPH"},{"system" : "http://loinc.org","code" : "LA26408-7","display" : "MALDI-TOF"},{"system" : "http://loinc.org","code" : "LA26808-8","display" : "Merging"},{"system" : "http://loinc.org","code" : "LA26414-5","display" : "Multiple complete digestion"},{"system" : "http://loinc.org","code" : "LA26415-2","display" : "MLPA"},{"system" : "http://loinc.org","code" : "LA26417-8","display" : "Optical mapping"},{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"},{"system" : "http://loinc.org","code" : "LA26419-4","display" : "qPCR (real-time PCR)"},{"system" : "http://loinc.org","code" : "LA26420-2","display" : "ROMA"},{"system" : "http://loinc.org","code" : "LA26809-6","display" : "Denaturing high-pressure liquid chromatography (DHPLC)"},{"system" : "http://loinc.org","code" : "LA26810-4","display" : "DNA hybridization"},{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"},{"system" : "http://loinc.org","code" : "LA26812-0","display" : "Single-stranded conformational polymorphism (SSCP)"},{"system" : "http://loinc.org","code" : "LA26813-8","display" : "Restriction fragment length polymorphism (RFLP)"}]}}

#673

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:752
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:32 GMT
last-modified:Fri, 19 Dec 2025 22:18:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943974

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#93044-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#674

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:780
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:32 GMT
last-modified:Fri, 19 Dec 2025 22:18:32 GMT
pragma:no-cache
server:nginx
x-request-id:252-943975

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53037-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#675

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:755
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:33 GMT
last-modified:Fri, 19 Dec 2025 22:18:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943976

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n32 32   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n32 0    : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n32 0    : 0ms  : Prepare include: \"()\"\r\n32 0    : 0ms  : Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n32 0    : 0ms  : Check \"http://loinc.org#81259-4\"\r\n32 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#676

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:752
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:33 GMT
last-modified:Fri, 19 Dec 2025 22:18:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943977

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48018-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#677

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:768
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:33 GMT
last-modified:Fri, 19 Dec 2025 22:18:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943979

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48001-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#678

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:776
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:33 GMT
last-modified:Fri, 19 Dec 2025 22:18:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943980

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#62374-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#679

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:806
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:33 GMT
last-modified:Fri, 19 Dec 2025 22:18:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943981

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48000-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#680

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:766
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:33 GMT
last-modified:Fri, 19 Dec 2025 22:18:33 GMT
pragma:no-cache
server:nginx
x-request-id:252-943982

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92821-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#681

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:756
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:34 GMT
last-modified:Fri, 19 Dec 2025 22:18:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943983

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84413-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#682

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:749
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:34 GMT
last-modified:Fri, 19 Dec 2025 22:18:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943985

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#84414-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#683

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:754
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:34 GMT
last-modified:Fri, 19 Dec 2025 22:18:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943986

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48004-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#684

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:769
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:34 GMT
last-modified:Fri, 19 Dec 2025 22:18:34 GMT
pragma:no-cache
server:nginx
x-request-id:252-943987

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51958-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#685

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:760
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:35 GMT
last-modified:Fri, 19 Dec 2025 22:18:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943988

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48005-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#686

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:35 GMT
last-modified:Fri, 19 Dec 2025 22:18:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943990

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82120-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#687

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:759
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:35 GMT
last-modified:Fri, 19 Dec 2025 22:18:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943991

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#51963-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#688

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:761
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:35 GMT
last-modified:Fri, 19 Dec 2025 22:18:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943992

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69548-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#689

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:761
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:35 GMT
last-modified:Fri, 19 Dec 2025 22:18:35 GMT
pragma:no-cache
server:nginx
x-request-id:252-943993

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81290-9\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#690

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:747
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:36 GMT
last-modified:Fri, 19 Dec 2025 22:18:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943994

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81291-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#691

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:766
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:36 GMT
last-modified:Fri, 19 Dec 2025 22:18:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943995

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48013-7\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#692

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:759
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:36 GMT
last-modified:Fri, 19 Dec 2025 22:18:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943996

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81254-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#693

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:36 GMT
last-modified:Fri, 19 Dec 2025 22:18:36 GMT
pragma:no-cache
server:nginx
x-request-id:252-943997

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81302-2\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#694

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:37 GMT
last-modified:Fri, 19 Dec 2025 22:18:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-943998

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81301-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#695

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:767
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:37 GMT
last-modified:Fri, 19 Dec 2025 22:18:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-943999

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#92822-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#696

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:37 GMT
last-modified:Fri, 19 Dec 2025 22:18:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-944000

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#69547-8\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#697

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:758
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:37 GMT
last-modified:Fri, 19 Dec 2025 22:18:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-944001

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#69551-0\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#698

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:750
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:37 GMT
last-modified:Fri, 19 Dec 2025 22:18:37 GMT
pragma:no-cache
server:nginx
x-request-id:252-944002

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48019-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#699

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:762
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:38 GMT
last-modified:Fri, 19 Dec 2025 22:18:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-944003

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#48002-0\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#700

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:38 GMT
last-modified:Fri, 19 Dec 2025 22:18:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-944004

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#81258-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#701

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:753
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:38 GMT
last-modified:Fri, 19 Dec 2025 22:18:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-944005

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82121-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#702

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:748
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:38 GMT
last-modified:Fri, 19 Dec 2025 22:18:38 GMT
pragma:no-cache
server:nginx
x-request-id:252-944006

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#53034-5\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#703

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:776
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:39 GMT
last-modified:Fri, 19 Dec 2025 22:18:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-944007

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#94186-4\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#704

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:765
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:39 GMT
last-modified:Fri, 19 Dec 2025 22:18:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-944008

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82309-6\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#705

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:759
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:39 GMT
last-modified:Fri, 19 Dec 2025 22:18:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-944009

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16   : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n16 0    : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0    : 0ms  : Prepare include: \"()\"\r\n16 0    : 0ms  : Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n16 0    : 0ms  : Check \"http://loinc.org#81252-9\"\r\n16 0    : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}

#706

POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0
Accept: application/fhir+json; fhirVersion=5.0
Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8
User-Agent: fhir/publisher

{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"96eb2679-2f95-4ad0-8d3e-561373fb23e9"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}

200
access-control-allow-methods:GET, POST, PUT, PATCH, DELETE
access-control-allow-origin:*
access-control-expose-headers:Content-Location, Location
cache-control:public, max-age=600
connection:keep-alive
content-length:773
content-type:application/fhir+json
date:Fri, 19 Dec 2025 22:18:39 GMT
last-modified:Fri, 19 Dec 2025 22:18:39 GMT
pragma:no-cache
server:nginx
x-request-id:252-944010

{"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0     : 0ms  : Analysing http://hl7.org/fhir/ValueSet/@all for validation purposes\r\n0 0     : 0ms  : Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0     : 0ms  : Prepare include: \"()\"\r\n0 0     : 0ms  : Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0     : 0ms  : Check \"http://loinc.org#82155-3\"\r\n0 0     : 0ms  : Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}