#1
GET https://tx.fhir.org/r5/metadata HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 User-Agent: fhir/publisher
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:4221 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:34 GMT pragma:no-cache server:nginx x-request-id:238-2637728 {"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20250821042601.640Z. Server version 3.8.7 built 20250821042601.640Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.7.8"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-3.8.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-10-16T23:40:34.029Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "3.8.7","releaseDate" : "2025-08-21T04:26:01.640Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}
#2
GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 User-Agent: fhir/publisher
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:133329 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:34 GMT pragma:no-cache server:nginx x-request-id:238-2637729 {"resourceType" : "TerminologyCapabilities","id" : "FhirServer","url" : "http://tx.fhir.org/r5/TerminologyCapabilities/tx","version" : "2.0.0","name" : "FHIRReferenceServerTerminologyCapabilities","title" : "FHIR Reference Server Terminology Capability Statement","status" : "active","date" : "2025-10-16T23:40:34.123Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Terminology Capability Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","codeSystem" : [{"uri" : "http://cap.org/eCP","version" : [{"code" : "4.000.001"}]},{"uri" : "http://cds-hooks.hl7.org/CodeSystem/indicator","version" : [{"code" : "5.0.0"}]},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-concept-status"},{"uri" : "http://devices.fhir.org/CodeSystem/MDC-designation-use"},{"uri" : "http://dicom.nema.org/resources/ontology/DCM","version" : [{"code" : "2025.3.20250714"}]},{"uri" : "http://fdasis.nlm.nih.gov","version" : [{"code" : "2024-06-22"}]},{"uri" : "http://healthit.gov/nhin/purposeofuse","version" : [{"code" : "2.0"}]},{"uri" : "http://hl7.org/fhir/account-aggregate","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-balance-term","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-billing-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/account-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-cardinality-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-condition-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-grouping-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-function","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-participant-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-precheck-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-reason-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-relationship-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-required-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/action-selection-behavior","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/address-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/address-use","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/administrable-dose-form","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/administrative-gender","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/adverse-event-actuality","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-category","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-criticality","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/allergy-intolerance-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/animal-tissue-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/appointmentstatus","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifactassessment-disposition","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifactassessment-information-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifactassessment-workflow-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifact-contribution-instance-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifact-contribution-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/artifact-url-classifier","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-direction-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-manual-completion-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-operator-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/assert-response-code-types","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/asset-availability","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/audit-event-action","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/audit-event-severity","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/binding-strength","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderived-productcodes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderivedproductdispense-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderived-product-property-type-codes","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/biologicallyderived-product-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/bundle-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/capability-statement-kind","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/care-team-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/catalogType","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/certainty-rating","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/certainty-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/characteristic-combination","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/characteristic-offset","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/chargeitem-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-artifact-classifier","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-classification-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-status-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/citation-summary-style","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-abstract-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-classification-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-part-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-artifact-status-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/cited-medium","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/claim-decision","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/claim-decision-reason","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/claim-outcome","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/claim-use","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/clinical-use-definition-category","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/clinical-use-definition-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/code-search-support","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/additional-binding-purpose","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/administration-subpotent-reason","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/biologicallyderivedproductdispense-match-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/biologicallyderivedproductdispense-origin-relationship","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/biologicallyderivedproductdispense-performer-function","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/devicedispense-status-reason","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/example","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/example-metadata","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/example-metadata-2","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/fhirpath-types","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/formularyitem-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/iana-link-relations","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/knowledge-representation-level","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/measure-aggregate-method","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-admin-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationdispense-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationdispense-status-reason","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-dose-aid","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-ingredientstrength","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-intended-performer-role","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationknowledge-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationrequest-intent","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medicationrequest-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-statement-adherence","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-statement-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/medication-status","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/submit-data-update-type","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/summary","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/task-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/transport-code","version" : [{"code" : "5.0.0"}]},{"uri" : "http://hl7.org/fhir/CodeSystem/usage-context-agreement-scope","version" : [{"code" : "5.0.0"}]},{"uri" : 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: [{"code" : "2021"}]},{"uri" : "urn:iso:std:iso:3166","version" : [{"code" : "2018"}]},{"uri" : "urn:iso:std:iso:3166","version" : [{"code" : "20210120"}]},{"uri" : "urn:iso:std:iso:4217"},{"uri" : "urn:iso-astm:E1762-95:2013","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1001.101.104.16592","version" : [{"code" : "5.0.0"}]},{"uri" : "urn:oid:1.2.36.1.2001.1005.17"},{"uri" : "urn:oid:2.16.840.1.113883.2.9.6.2.7","version" : [{"code" : "ISCO-08"}]},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8"},{"uri" : "urn:oid:2.16.840.1.113883.3.1937.98.5.8","version" : [{"code" : "5.0.0"}]}],"expansion" : {"parameter" : [{"name" : "cache-id","documentation" : "This server supports caching terminology resources between calls. Clients only need to send value sets and codesystems once; there after they are automatically in scope for calls with the same cache-id. The cache is retained for 30 min from last call"},{"name" : "tx-resource","documentation" : "Additional valuesets needed for evaluation e.g. value sets referred to from the import statement of the value set being expanded"},{"name" : "_incomplete"},{"name" : "abstract"},{"name" : "activeOnly"},{"name" : "check-system-version"},{"name" : "count"},{"name" : "default-to-latest-version"},{"name" : "displayLanguage"},{"name" : "excludeNested"},{"name" : "excludeNotForUI"},{"name" : "excludePostCoordinated"},{"name" : "force-system-version"},{"name" : "inactive"},{"name" : "includeAlternateCodes"},{"name" : "includeDefinition"},{"name" : "includeDesignations"},{"name" : "incomplete-ok"},{"name" : "limitedExpansion"},{"name" : "mode","documentation" : "=lenient-display-validation"},{"name" : "no-cache"},{"name" : "offset"},{"name" : "profile"},{"name" : "property"},{"name" : "system-version"},{"name" : "valueSetMode","documentation" : "= CHECK_MEMBERSHIP_ONLY | NO_MEMBERSHIP_CHECK"}]}}
#3
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1733 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637758 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#4
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1747 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637760 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#5
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1754 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637762 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#6
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637764 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#7
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30102-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:810 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637766 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30102-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#8
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:802 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637768 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#9
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637770 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#10
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637772 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#11
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637774 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#12
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1585 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637776 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#13
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637778 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#14
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:44 GMT last-modified:Thu, 16 Oct 2025 23:40:44 GMT pragma:no-cache server:nginx x-request-id:238-2637780 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#15
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637782 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#16
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637784 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#17
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637786 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#18
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637788 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#19
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637790 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#20
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637792 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#21
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637794 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#22
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637796 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#23
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637798 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#24
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637800 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#25
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637802 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#26
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:45 GMT last-modified:Thu, 16 Oct 2025 23:40:45 GMT pragma:no-cache server:nginx x-request-id:238-2637804 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#27
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637806 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#28
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637808 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#29
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637810 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#30
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637812 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#31
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637814 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#32
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637816 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#33
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637818 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#34
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637822 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#35
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637824 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#36
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637827 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#37
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637829 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#38
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637831 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#39
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:46 GMT last-modified:Thu, 16 Oct 2025 23:40:46 GMT pragma:no-cache server:nginx x-request-id:238-2637833 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#40
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637835 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#41
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637837 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#42
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637839 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#43
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637841 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#44
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637843 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#45
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637846 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#46
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637848 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#47
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637851 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#48
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637853 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#49
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637855 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#50
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637857 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#51
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637859 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#52
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:47 GMT last-modified:Thu, 16 Oct 2025 23:40:47 GMT pragma:no-cache server:nginx x-request-id:238-2637861 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#53
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637863 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#54
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637865 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#55
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637867 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#56
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637869 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#57
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637871 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#58
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637873 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#59
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637875 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#60
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637877 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#61
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637879 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#62
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637881 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#63
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637883 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#64
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637885 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#65
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:48 GMT last-modified:Thu, 16 Oct 2025 23:40:48 GMT pragma:no-cache server:nginx x-request-id:238-2637887 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#66
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637889 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#67
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637891 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#68
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637893 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#69
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637895 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#70
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637897 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#71
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637899 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#72
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637901 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#73
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637903 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#74
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637905 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#75
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637907 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#76
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637909 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#77
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637911 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#78
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:49 GMT last-modified:Thu, 16 Oct 2025 23:40:49 GMT pragma:no-cache server:nginx x-request-id:238-2637913 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#79
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637915 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#80
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637917 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#81
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637919 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#82
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:804 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637921 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#83
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:799 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637923 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#84
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637926 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}
#85
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:810 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637928 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#86
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:802 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637930 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#87
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:812 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637932 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#88
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637934 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#89
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637936 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#90
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:50 GMT last-modified:Thu, 16 Oct 2025 23:40:50 GMT pragma:no-cache server:nginx x-request-id:238-2637938 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#91
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:804 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637940 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#92
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:895 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637942 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#93
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:809 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637944 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#94
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1626 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637946 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#95
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:797 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637948 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#96
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637950 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#97
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:810 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637952 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#98
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:879 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637954 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#99
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:793 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:51 GMT last-modified:Thu, 16 Oct 2025 23:40:51 GMT pragma:no-cache server:nginx x-request-id:238-2637956 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#100
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637958 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#101
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637960 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#102
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:811 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637962 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#103
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:812 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637964 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#104
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:791 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637966 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#105
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:823 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637968 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#106
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"%"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:795 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637970 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "%"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "%"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#% (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#%\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}
#107
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:796 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637972 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#108
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:795 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637974 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}
#109
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637976 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#110
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637978 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81301-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#111
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637980 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#112
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:823 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:52 GMT last-modified:Thu, 16 Oct 2025 23:40:52 GMT pragma:no-cache server:nginx x-request-id:238-2637982 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#113
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:798 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637984 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#114
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637986 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#115
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:867 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637988 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#116
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:886 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637990 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#117
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637992 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#118
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637994 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#119
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637996 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}
#120
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:809 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2637998 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#121
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51969-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2638000 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#122
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1550 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:53 GMT last-modified:Thu, 16 Oct 2025 23:40:53 GMT pragma:no-cache server:nginx x-request-id:238-2638002 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}
#123
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638004 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#124
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638006 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#125
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638008 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "version","valueString" : "137"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP|137\"\r\n"}]}
#126
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81299-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:820 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638010 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81299-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#127
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81300-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:812 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638012 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81300-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#128
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638014 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#129
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638016 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#130
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1550 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638018 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}
#131
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"1/1000000"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:827 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638020 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "1/1000000"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "1/1000000"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#1/1000000 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#1/1000000\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}
#132
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:908 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638022 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.31.0)\" (content = complete)\r\n"}]}
#133
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:54 GMT last-modified:Thu, 16 Oct 2025 23:40:54 GMT pragma:no-cache server:nginx x-request-id:238-2638024 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#134
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:902 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638026 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#135
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638028 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#136
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:879 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638030 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#137
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638032 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#138
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:890 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638034 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#139
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:882 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638036 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#140
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:55 GMT last-modified:Thu, 16 Oct 2025 23:40:55 GMT pragma:no-cache server:nginx x-request-id:238-2638038 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#141
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638040 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#142
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:890 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638042 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#143
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:795 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638046 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#144
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1607 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638050 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#145
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638052 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#146
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1617 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638055 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#147
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638058 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#148
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638060 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#149
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638063 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#150
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1795 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:56 GMT last-modified:Thu, 16 Oct 2025 23:40:56 GMT pragma:no-cache server:nginx x-request-id:238-2638065 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}
#151
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1696 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638068 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}
#152
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638070 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#153
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:918 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638072 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#154
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:849 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638074 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48000-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#155
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638076 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000003.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#156
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:962 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638078 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#157
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:886 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638080 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#158
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:57 GMT last-modified:Thu, 16 Oct 2025 23:40:57 GMT pragma:no-cache server:nginx x-request-id:238-2638082 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#159
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:898 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638084 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#160
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638086 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#161
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:817 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638088 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#162
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:826 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638090 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94186-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#163
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638092 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82309-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#164
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638094 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#165
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638096 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#166
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638098 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#167
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638100 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#168
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638102 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#169
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1530 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638104 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX,t(9;22)(q34;q4)"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX,t(9;22)(q34;q4) (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX,t(9;22)(q34;q4)\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}
#170
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1482 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:58 GMT last-modified:Thu, 16 Oct 2025 23:40:58 GMT pragma:no-cache server:nginx x-request-id:238-2638106 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}
#171
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638108 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#172
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:874 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638110 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#173
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638112 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#174
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638114 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#175
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638116 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000009.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#176
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:902 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638118 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#177
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:879 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638120 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#178
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:867 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:40:59 GMT last-modified:Thu, 16 Oct 2025 23:40:59 GMT pragma:no-cache server:nginx x-request-id:238-2638122 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#179
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638124 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#180
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:898 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638126 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#181
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638128 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#182
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:859 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638130 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#183
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:867 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638132 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#184
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638134 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#185
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:954 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638136 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#186
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:00 GMT last-modified:Thu, 16 Oct 2025 23:41:00 GMT pragma:no-cache server:nginx x-request-id:238-2638138 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000023.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#187
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:998 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638140 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#188
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:791 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638142 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#189
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638144 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000017.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#190
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA30100-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638146 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30100-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#191
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1585 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638148 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#192
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:863 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638150 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#193
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638152 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#194
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638154 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#195
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:01 GMT last-modified:Thu, 16 Oct 2025 23:41:01 GMT pragma:no-cache server:nginx x-request-id:238-2638156 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000016.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#196
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:02 GMT last-modified:Thu, 16 Oct 2025 23:41:02 GMT pragma:no-cache server:nginx x-request-id:238-2638158 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#197
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:02 GMT last-modified:Thu, 16 Oct 2025 23:41:02 GMT pragma:no-cache server:nginx x-request-id:238-2638160 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#198
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:02 GMT last-modified:Thu, 16 Oct 2025 23:41:02 GMT pragma:no-cache server:nginx x-request-id:238-2638162 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#199
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:02 GMT last-modified:Thu, 16 Oct 2025 23:41:02 GMT pragma:no-cache server:nginx x-request-id:238-2638164 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#200
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1689 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:02 GMT last-modified:Thu, 16 Oct 2025 23:41:02 GMT pragma:no-cache server:nginx x-request-id:238-2638167 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}
#201
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA26421-0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:822 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:03 GMT last-modified:Thu, 16 Oct 2025 23:41:03 GMT pragma:no-cache server:nginx x-request-id:238-2638169 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26421-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#202
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:379 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:03 GMT server:nginx x-request-id:238-2638172 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}
#203
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs-inc-0","status":"active","compose":{"inactive":false,"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:379 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:03 GMT server:nginx x-request-id:238-2638175 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}
#204
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1557 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:03 GMT last-modified:Thu, 16 Oct 2025 23:41:03 GMT pragma:no-cache server:nginx x-request-id:238-2638177 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002072\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#205
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1557 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:03 GMT last-modified:Thu, 16 Oct 2025 23:41:03 GMT pragma:no-cache server:nginx x-request-id:238-2638181 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#206
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2061 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:03 GMT last-modified:Thu, 16 Oct 2025 23:41:03 GMT pragma:no-cache server:nginx x-request-id:238-2638183 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:647b65f0-1bcb-41cc-a8e4-255b9dbe8149","timestamp" : "2025-10-16T23:41:03.993Z","total" : 19,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA10315-2","display" : "Ultrarapid metabolizer"},{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"},{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"},{"system" : "http://loinc.org","code" : "LA10317-8","display" : "Intermediate metabolizer"},{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"},{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"},{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"},{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"},{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"},{"system" : "http://loinc.org","code" : "LA9660-7","display" : "Presumed resistant"},{"system" : "http://loinc.org","code" : "LA9661-5","display" : "Presumed responsive"},{"system" : "http://loinc.org","code" : "LA6682-4","display" : "Unknown Significance"},{"system" : "http://loinc.org","code" : "LA6675-8","display" : "Benign"},{"system" : "http://loinc.org","code" : "LA6674-1","display" : "Presumed Benign"},{"system" : "http://loinc.org","code" : "LA9662-3","display" : "Presumed non-responsive"},{"system" : "http://loinc.org","code" : "LA25392-4","display" : "Increased function"},{"system" : "http://loinc.org","code" : "LA25393-2","display" : "Normal function"},{"system" : "http://loinc.org","code" : "LA25395-7","display" : "Decreased function"},{"system" : "http://loinc.org","code" : "LA25394-0","display" : "Poor function"}]}}
#207
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:855 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT last-modified:Thu, 16 Oct 2025 23:41:04 GMT pragma:no-cache server:nginx x-request-id:238-2638186 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:9b14e3a8-9d5c-4cf3-b610-04ecf2425475","timestamp" : "2025-10-16T23:41:04.086Z","total" : 2,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "version","valueUri" : "http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201"}],"contains" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial (finding)"},{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial (finding)"}]}}
#208
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://loinc.org","concept":[{"code":"85337-4","display":"Estrogen receptor Ag Immune stain Ql (Breast cancer specimen)"},{"code":"72382-5","display":"HER2 IA Qn (Tiss)"},{"code":"77637-7","display":"HLA-A and B and C (class I) IgG panel IA [Identifier]"},{"code":"40557-1","display":"Progesterone receptor Ag Immune stain Ql (Tiss)"},{"code":"85147-7","display":"PD-L1 by clone 22C3 Immune stain Doc (Tiss)"},{"code":"59025-7","display":"Neutrophil Ab FC Qn (S)"},{"code":"59003-4","display":"Lactoferrin Ab IA Qn (S)"},{"code":"10495-0","display":"Insulin Ag Immune stain Ql (Tiss)"},{"code":"16550-6","display":"Carbohydrates Nom (U)"},{"code":"2569-2","display":"Lipids (S) [Mass/Vol]"},{"code":"4551-8","display":"Hemoglobin A2 (Bld) [Mass fraction]"},{"code":"19195-7","display":"Prostate specific Ag Qn"},{"code":"64083-9","display":"MGMT gene methylation score Molgen (Tiss) [Ratio]"},{"code":"62862-8","display":"Microsatellite instability Immune stain Ql (Tiss)"},{"code":"81704-9","display":"Microsatellite instability marker D17S250 Ql (Cancer specimen)"},{"code":"94077-5","display":"Tumor mutation burden Ql (Tumor) [Interp]"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2403 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT last-modified:Thu, 16 Oct 2025 23:41:04 GMT pragma:no-cache server:nginx x-request-id:238-2638189 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:fc10920d-6ada-4021-ae5d-2b3d6f2db3bb","timestamp" : "2025-10-16T23:41:04.144Z","total" : 16,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "85337-4","display" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"system" : "http://loinc.org","code" : "77637-7","display" : "HLA-A and B and C (class I) IgG panel [Identifier] - Serum or Plasma by Immunoassay"},{"system" : "http://loinc.org","code" : "40557-1","display" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"system" : "http://loinc.org","code" : "59025-7","display" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"},{"system" : "http://loinc.org","code" : "59003-4","display" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"},{"system" : "http://loinc.org","code" : "10495-0","display" : "Insulin Ag [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "16550-6","display" : "Carbohydrates [Identifier] in Urine"},{"system" : "http://loinc.org","code" : "2569-2","display" : "Lipids [Mass/volume] in Serum"},{"system" : "http://loinc.org","code" : "4551-8","display" : "Hemoglobin A2/Hemoglobin.total in Blood"},{"system" : "http://loinc.org","code" : "19195-7","display" : "Prostate specific Ag [Units/volume] in Serum or Plasma"},{"system" : "http://loinc.org","code" : "64083-9","display" : "MGMT gene methylation score in Tissue by Molecular genetics method"},{"system" : "http://loinc.org","code" : "62862-8","display" : "Microsatellite instability [Presence] in Tissue by Immune stain"},{"system" : "http://loinc.org","code" : "81704-9","display" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"},{"system" : "http://loinc.org","code" : "94077-5","display" : "Tumor mutation burden [Interpretation]"}]}}
#209
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C120465","display":"Homologous Recombination Repair Deficiency"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:627 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT server:nginx x-request-id:238-2638194 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}
#210
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-biomarker-code-vs-inc-1","status":"active","compose":{"inactive":false,"include":[{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","concept":[{"code":"C120465","display":"Homologous Recombination Repair Deficiency"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:627 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT server:nginx x-request-id:238-2638197 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\"</p></div>"},"issue" : [{"severity" : "error","code" : "invalid","details" : {"text" : "The code system definition for http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl is a fragment, so this expansion is not permitted unless the expansion parameter \"incomplete-ok\" has a value of \"true\""}}]}
#211
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1564 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT last-modified:Thu, 16 Oct 2025 23:41:04 GMT pragma:no-cache server:nginx x-request-id:238-2638201 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001537\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#212
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"jurisdiction","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"vocab"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"deprecated"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/jurisdiction","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.48"}],"version":"6.0.0-ballot3","name":"JurisdictionValueSet","title":"Jurisdiction ValueSet","status":"draft","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International / Terminology Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]},{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/Vocab"}]}],"description":"This value set defines a base set of codes for country, country subdivision and region for indicating where a resource is intended to be used. \r\n \r\n Note: The codes for countries and country subdivisions are taken from [ISO 3166](https://www.iso.org/iso-3166-country-codes.html) while the codes for \"supra-national\" regions are from [UN Standard country or area codes for statistical use (M49)](http://unstats.un.org/unsd/methods/m49/m49.htm).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:iso:std:iso:3166"},{"system":"urn:iso:std:iso:3166:-2"},{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","filter":[{"property":"class","op":"=","value":"region"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2222 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT last-modified:Thu, 16 Oct 2025 23:41:04 GMT pragma:no-cache server:nginx x-request-id:238-2638209 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unstats.un.org/unsd/methods/m49/m49.htm"},{"name" : "code","valueCode" : "001"},{"name" : "display","valueString" : "World"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm","code" : "001","display" : "World"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "MSG_DEPRECATED"}],"severity" : "information","code" : "business-rule","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "status-check"}],"text" : "Reference to deprecated ValueSet http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166|2018\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"urn:iso:std:iso:3166:-2|2021 (from fhir.tx.support.r4#0.31.0)\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: \"http://unstats.un.org/unsd/methods/m49/m49.htm|\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Validate \"[http://unstats.un.org/unsd/methods/m49/m49.htm#001 (\"World\")]\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Check \"http://unstats.un.org/unsd/methods/m49/m49.htm#001\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: CodeSystem found: http://unstats.un.org/unsd/methods/m49/m49.htm| for http://unstats.un.org/unsd/methods/m49/m49.htm\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/jurisdiction|6.0.0-ballot3: Filter \"class = region\": Code \"001\" found in http://unstats.un.org/unsd/methods/m49/m49.htm|\r\n"}]}
#213
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1553 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:04 GMT last-modified:Thu, 16 Oct 2025 23:41:04 GMT pragma:no-cache server:nginx x-request-id:238-2638219 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002072\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#214
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1553 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638222 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#215
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10315-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:817 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638227 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10315-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Ultrarapid metabolizer"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA10315-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA10315-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#216
POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25391-6"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25390-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA10317-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9657-3"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19542-2"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA19541-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6676-6"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6677-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9660-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9661-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6682-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6675-8"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6674-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9662-3"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25392-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25393-2"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25395-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA25394-0"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:5840 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638229 {"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA10317-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Intermediate metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9660-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed resistant"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9661-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6682-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Unknown Significance"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6675-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6674-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed Benign"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9662-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Presumed non-responsive"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25392-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25393-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25395-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Decreased function"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25394-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor function"}]}}]}
#217
GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fsnomed.info%2Fsct HTTP/1.0 User-Agent: hapi-fhir-tooling-client Accept: application/fhir+json
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:238 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638234 {"resourceType" : "Bundle","id" : "db206f96-638e-41ea-9168-058cb0bbdf","meta" : {"lastUpdated" : "2025-10-16T23:41:05.398Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://snomed.info/sct"}]}
#218
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"444734003"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:983 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638237 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#444734003 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#444734003\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#219
POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://snomed.info/sct","code":"399223003"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:459 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638240 {"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"}]}}]}
#220
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85337-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:862 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638250 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85337-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Estrogen receptor Ag [Presence] in Breast cancer specimen by Immune stain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#85337-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#85337-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#221
POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"72382-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"77637-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"40557-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"85147-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"59025-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"59003-4"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, 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Serum or Plasma by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "40557-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Progesterone receptor Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "59025-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Neutrophil Ab [Units/volume] in Serum by Flow cytometry (FC)"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "59003-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Lactoferrin Ab [Units/volume] in Serum by Immunoassay"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "10495-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Insulin Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "16550-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Carbohydrates [Identifier] in Urine"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "2569-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Lipids [Mass/volume] in Serum"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "4551-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Hemoglobin A2/Hemoglobin.total in Blood"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "19195-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Prostate specific Ag [Units/volume] in Serum or Plasma"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "64083-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MGMT gene methylation score in Tissue by Molecular genetics method"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62862-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Presence] in Tissue by Immune stain"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81704-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability marker D17S250 in Cancer specimen Qualitative"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94077-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Tumor mutation burden [Interpretation]"}]}}]}
#222
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C120465"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1775 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:05 GMT last-modified:Thu, 16 Oct 2025 23:41:05 GMT pragma:no-cache server:nginx x-request-id:238-2638257 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C120465"},{"name" : "message","valueString" : "Unknown Code 'C120465' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODE_IN_FRAGMENT"}],"severity" : "warning","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "invalid-code"}],"text" : "Unknown Code 'C120465' in the CodeSystem 'http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl' version '' - note that the code system is labeled as a fragment, so the code may be valid in some other fragment"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120465 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C120465\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.31.0)\" (content = fragment)\r\n"}]}
#223
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1560 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:06 GMT last-modified:Thu, 16 Oct 2025 23:41:06 GMT pragma:no-cache server:nginx x-request-id:238-2638259 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001537\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#224
POST https://tx.fhir.org/r5/ValueSet/$batch-validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA9658-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6692-3"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6686-5"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000035"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6687-3"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6688-1"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6689-9"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"LA6690-7"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}},{"name":"validation","resource":{"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true}]}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:9608 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:06 GMT last-modified:Thu, 16 Oct 2025 23:41:06 GMT pragma:no-cache server:nginx x-request-id:238-2638262 {"resourceType" : "Parameters","parameter" : [{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9658-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Wild type"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6692-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Deletion"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6686-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Duplication"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000035"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6687-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Insertion"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6688-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Insertion/Deletion"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000032"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6689-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Inversion"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6690-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Substitution"}]}},{"name" : "validation","resource" : {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}}]}}]}
#225
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:915 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:07 GMT last-modified:Thu, 16 Oct 2025 23:41:07 GMT pragma:no-cache server:nginx x-request-id:238-2638264 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#226
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:950 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:07 GMT last-modified:Thu, 16 Oct 2025 23:41:07 GMT pragma:no-cache server:nginx x-request-id:238-2638267 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#227
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:925 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:07 GMT last-modified:Thu, 16 Oct 2025 23:41:07 GMT pragma:no-cache server:nginx x-request-id:238-2638271 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#228
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"5792-7"}},{"name":"valueset-membership-only","valueBoolean":true},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4034-6"}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"displayLanguage","valueCode":"en-US"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1310 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:08 GMT last-modified:Thu, 16 Oct 2025 23:41:08 GMT pragma:no-cache server:nginx x-request-id:238-2638274 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "5792-7"},{"name" : "message","valueString" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "The provided code 'http://loinc.org#5792-7' was not found in the value set 'http://loinc.org/vs/LL4034-6'"},"location" : ["Coding.code"],"expression" : ["Coding.code"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Parameters: disp-lang=en-US, membership-only, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Validate \"[http://loinc.org#5792-7 (\"\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4034-6: Check \"http://loinc.org#5792-7\"\r\n"}]}
#229
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:915 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:08 GMT last-modified:Thu, 16 Oct 2025 23:41:08 GMT pragma:no-cache server:nginx x-request-id:238-2638276 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#230
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:931 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:08 GMT last-modified:Thu, 16 Oct 2025 23:41:08 GMT pragma:no-cache server:nginx x-request-id:238-2638279 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#231
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:946 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:08 GMT last-modified:Thu, 16 Oct 2025 23:41:08 GMT pragma:no-cache server:nginx x-request-id:238-2638281 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#232
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48000-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:969 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:09 GMT last-modified:Thu, 16 Oct 2025 23:41:09 GMT pragma:no-cache server:nginx x-request-id:238-2638284 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48000-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48000-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#233
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:936 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:10 GMT last-modified:Thu, 16 Oct 2025 23:41:10 GMT pragma:no-cache server:nginx x-request-id:238-2638286 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#234
GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fdicom.nema.org%2Fmedical%2Fdicom%2Fcurrent%2Foutput%2Fchtml%2Fpart16%2Fsect_CID_33.html HTTP/1.0 User-Agent: hapi-fhir-tooling-client Accept: application/fhir+json
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:4699 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:10 GMT pragma:no-cache server:nginx x-request-id:238-2638288 {"resourceType" : "Bundle","id" : "12dd6139-a62b-4f42-b195-ff9df3d63f","meta" : {"lastUpdated" : "2025-10-16T23:41:10.858Z"},"type" : "searchset","total" : 1,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html"}],"entry" : [{"fullUrl" : "http://tx.fhir.org/r5/ValueSet/dicom-cid-33-Modality","resource" : {"resourceType" : "ValueSet","id" : "dicom-cid-33-Modality","url" : "http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:1.2.840.10008.6.1.1283"}],"version" : "2025.3.20250714","name" : "Modality","status" : "active","experimental" : false,"date" : "2025-07-14","publisher" : "NEMA MITA DICOM","description" : "Transitive closure of CID 33 Modality","copyright" : "© 2025 NEMA","compose" : {"include" : [{"system" : "http://dicom.nema.org/resources/ontology/DCM","concept" : [{"code" : "BMD","display" : "Bone Mineral Densitometry"},{"code" : "SM","display" : "Slide Microscopy"},{"code" : "EOG","display" : "Electrooculography"},{"code" : "SR","display" : "Structured Report Document"},{"code" : "FID","display" : "Spatial Fiducials"},{"code" : "OP","display" : "Ophthalmic Photography"},{"code" : "OT","display" : "Other Modality"},{"code" : "KO","display" : "Key Object Selection"},{"code" : "GM","display" : "General Microscopy"},{"code" : "ECG","display" : "Electrocardiography"},{"code" : "XA","display" : "X-Ray Angiography"},{"code" : "IOL","display" : "Intraocular Lens Calculation"},{"code" : "XC","display" : "External-camera Photography"},{"code" : "ASMT","display" : "Content Assessment Result"},{"code" : "DMS","display" : "Dermoscopy"},{"code" : "IVUS","display" : "Intravascular Ultrasound"},{"code" : "CR","display" : "Computed Radiography"},{"code" : "CT","display" : "Computed Tomography"},{"code" : "PA","display" : "Photoacoustic"},{"code" : "OSS","display" : "Optical Surface Scanner"},{"code" : "TG","display" : "Thermography"},{"code" : "REG","display" : "Registration"},{"code" : "LEN","display" : "Lensometry"},{"code" : "TEXTUREMAP","display" : "Texture Map"},{"code" : "RTDOSE","display" : "RT Dose"},{"code" : "OPTENF","display" : "Ophthalmic Tomography En Face"},{"code" : "HC","display" : "Hard Copy"},{"code" : "RTPLAN","display" : "RT Plan"},{"code" : "HD","display" : "Hemodynamic"},{"code" : "OCT","display" : "Optical Coherence Tomography"},{"code" : "BDUS","display" : "Ultrasound Bone Densitometry"},{"code" : "M3D","display" : "3D Manufacturing Modeling System"},{"code" : "DG","display" : "Diaphanography"},{"code" : "PR","display" : "Presentation State"},{"code" : "PT","display" : "Positron emission tomography"},{"code" : "LS","display" : "Laser surface scan"},{"code" : "EPS","display" : "Cardiac Electrophysiology"},{"code" : "PX","display" : "Panoramic X-Ray"},{"code" : "OPM","display" : "Ophthalmic Mapping"},{"code" : "OPTBSV","display" : "Ophthalmic Tomography B-scan Volume Analysis"},{"code" : "OPV","display" : "Ophthalmic Visual Field"},{"code" : "DX","display" : "Digital Radiography"},{"code" : "OPT","display" : "Ophthalmic Tomography"},{"code" : "DOC","display" : "Document"},{"code" : "RTRECORD","display" : "RT Treatment Record"},{"code" : "MG","display" : "Mammography"},{"code" : "US","display" : "Ultrasound"},{"code" : "IVOCT","display" : "Intravascular Optical Coherence Tomography"},{"code" : "EMG","display" : "Electromyography"},{"code" : "RTSTRUCT","display" : "RT Structure Set"},{"code" : "MR","display" : "Magnetic Resonance"},{"code" : "IO","display" : "Intra-oral Radiography"},{"code" : "EEG","display" : "Electroencephalography"},{"code" : "RTIMAGE","display" : "RT Image"},{"code" : "VA","display" : "Visual Acuity"},{"code" : "RESP","display" : "Respiratory"},{"code" : "ES","display" : "Endoscopy"},{"code" : "RWV","display" : "Real World Value Map"},{"code" : "AR","display" : "Autorefraction"},{"code" : "POS","display" : "Position Sensor"},{"code" : "SEG","display" : "Segmentation"},{"code" : "RG","display" : "Radiographic imaging"},{"code" : "RF","display" : "Radiofluoroscopy"},{"code" : "AU","display" : "Audio"},{"code" : "KER","display" : "Keratometry"},{"code" : "SMR","display" : "Stereometric Relationship"},{"code" : "CTPROTOCOL","display" : "CT Protocol"},{"code" : "STAIN","display" : "Automated Slide Stainer"},{"code" : "OAM","display" : "Ophthalmic Axial Measurements"},{"code" : "NM","display" : "Nuclear Medicine"},{"code" : "PLAN","display" : "Plan"},{"code" : "BI","display" : "Biomagnetic Imaging"},{"code" : "SRF","display" : "Subjective Refraction"},{"code" : "CFM","display" : "Confocal Microscopy"}]}]}}}]}
#235
GET https://tx.fhir.org/r5/ValueSet/dicom-cid-33-Modality HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 User-Agent: fhir/publisher
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:4308 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:10 GMT pragma:no-cache server:nginx x-request-id:238-2638289 {"resourceType" : "ValueSet","id" : "dicom-cid-33-Modality","url" : "http://dicom.nema.org/medical/dicom/current/output/chtml/part16/sect_CID_33.html","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:1.2.840.10008.6.1.1283"}],"version" : "2025.3.20250714","name" : "Modality","status" : "active","experimental" : false,"date" : "2025-07-14","publisher" : "NEMA MITA DICOM","description" : "Transitive closure of CID 33 Modality","copyright" : "© 2025 NEMA","compose" : {"include" : [{"system" : "http://dicom.nema.org/resources/ontology/DCM","concept" : [{"code" : "BMD","display" : "Bone Mineral Densitometry"},{"code" : "SM","display" : "Slide Microscopy"},{"code" : "EOG","display" : "Electrooculography"},{"code" : "SR","display" : "Structured Report Document"},{"code" : "FID","display" : "Spatial Fiducials"},{"code" : "OP","display" : "Ophthalmic Photography"},{"code" : "OT","display" : "Other Modality"},{"code" : "KO","display" : "Key Object Selection"},{"code" : "GM","display" : "General Microscopy"},{"code" : "ECG","display" : "Electrocardiography"},{"code" : "XA","display" : "X-Ray Angiography"},{"code" : "IOL","display" : "Intraocular Lens Calculation"},{"code" : "XC","display" : "External-camera Photography"},{"code" : "ASMT","display" : "Content Assessment Result"},{"code" : "DMS","display" : "Dermoscopy"},{"code" : "IVUS","display" : "Intravascular Ultrasound"},{"code" : "CR","display" : "Computed Radiography"},{"code" : "CT","display" : "Computed Tomography"},{"code" : "PA","display" : "Photoacoustic"},{"code" : "OSS","display" : "Optical Surface Scanner"},{"code" : "TG","display" : "Thermography"},{"code" : "REG","display" : "Registration"},{"code" : "LEN","display" : "Lensometry"},{"code" : "TEXTUREMAP","display" : "Texture Map"},{"code" : "RTDOSE","display" : "RT Dose"},{"code" : "OPTENF","display" : "Ophthalmic Tomography En Face"},{"code" : "HC","display" : "Hard Copy"},{"code" : "RTPLAN","display" : "RT Plan"},{"code" : "HD","display" : "Hemodynamic"},{"code" : "OCT","display" : "Optical Coherence Tomography"},{"code" : "BDUS","display" : "Ultrasound Bone Densitometry"},{"code" : "M3D","display" : "3D Manufacturing Modeling System"},{"code" : "DG","display" : "Diaphanography"},{"code" : "PR","display" : "Presentation State"},{"code" : "PT","display" : "Positron emission tomography"},{"code" : "LS","display" : "Laser surface scan"},{"code" : "EPS","display" : "Cardiac Electrophysiology"},{"code" : "PX","display" : "Panoramic X-Ray"},{"code" : "OPM","display" : "Ophthalmic Mapping"},{"code" : "OPTBSV","display" : "Ophthalmic Tomography B-scan Volume Analysis"},{"code" : "OPV","display" : "Ophthalmic Visual Field"},{"code" : "DX","display" : "Digital Radiography"},{"code" : "OPT","display" : "Ophthalmic Tomography"},{"code" : "DOC","display" : "Document"},{"code" : "RTRECORD","display" : "RT Treatment Record"},{"code" : "MG","display" : "Mammography"},{"code" : "US","display" : "Ultrasound"},{"code" : "IVOCT","display" : "Intravascular Optical Coherence Tomography"},{"code" : "EMG","display" : "Electromyography"},{"code" : "RTSTRUCT","display" : "RT Structure Set"},{"code" : "MR","display" : "Magnetic Resonance"},{"code" : "IO","display" : "Intra-oral Radiography"},{"code" : "EEG","display" : "Electroencephalography"},{"code" : "RTIMAGE","display" : "RT Image"},{"code" : "VA","display" : "Visual Acuity"},{"code" : "RESP","display" : "Respiratory"},{"code" : "ES","display" : "Endoscopy"},{"code" : "RWV","display" : "Real World Value Map"},{"code" : "AR","display" : "Autorefraction"},{"code" : "POS","display" : "Position Sensor"},{"code" : "SEG","display" : "Segmentation"},{"code" : "RG","display" : "Radiographic imaging"},{"code" : "RF","display" : "Radiofluoroscopy"},{"code" : "AU","display" : "Audio"},{"code" : "KER","display" : "Keratometry"},{"code" : "SMR","display" : "Stereometric Relationship"},{"code" : "CTPROTOCOL","display" : "CT Protocol"},{"code" : "STAIN","display" : "Automated Slide Stainer"},{"code" : "OAM","display" : "Ophthalmic Axial Measurements"},{"code" : "NM","display" : "Nuclear Medicine"},{"code" : "PLAN","display" : "Plan"},{"code" : "BI","display" : "Biomagnetic Imaging"},{"code" : "SRF","display" : "Subjective Refraction"},{"code" : "CFM","display" : "Confocal Microscopy"}]}]}}
#236
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:928 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:11 GMT last-modified:Thu, 16 Oct 2025 23:41:11 GMT pragma:no-cache server:nginx x-request-id:238-2638294 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#237
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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#238
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:919 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:12 GMT last-modified:Thu, 16 Oct 2025 23:41:12 GMT pragma:no-cache server:nginx x-request-id:238-2638306 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#239
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:924 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:14 GMT last-modified:Thu, 16 Oct 2025 23:41:14 GMT pragma:no-cache server:nginx x-request-id:238-2638311 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#240
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:932 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:14 GMT last-modified:Thu, 16 Oct 2025 23:41:14 GMT pragma:no-cache server:nginx x-request-id:238-2638313 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#241
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:930 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:14 GMT last-modified:Thu, 16 Oct 2025 23:41:14 GMT pragma:no-cache server:nginx x-request-id:238-2638315 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#242
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:911 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:14 GMT last-modified:Thu, 16 Oct 2025 23:41:14 GMT pragma:no-cache server:nginx x-request-id:238-2638319 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#243
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:929 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:15 GMT last-modified:Thu, 16 Oct 2025 23:41:15 GMT pragma:no-cache server:nginx x-request-id:238-2638321 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#244
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:924 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:15 GMT last-modified:Thu, 16 Oct 2025 23:41:15 GMT pragma:no-cache server:nginx x-request-id:238-2638323 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#245
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:931 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638325 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#246
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:910 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638328 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#247
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:929 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638330 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#248
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:929 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638332 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#249
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:943 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638334 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#250
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81301-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:943 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638336 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81301-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81301-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#251
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:937 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638338 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#252
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:928 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638340 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#253
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:928 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638342 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#254
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:920 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:16 GMT last-modified:Thu, 16 Oct 2025 23:41:16 GMT pragma:no-cache server:nginx x-request-id:238-2638344 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#255
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:925 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638346 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#256
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:936 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638348 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#257
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:923 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638350 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#258
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:911 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638352 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#259
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94186-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:939 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638354 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94186-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94186-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#260
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82309-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:935 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638356 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82309-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82309-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#261
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:929 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638358 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#262
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:936 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:41:17 GMT last-modified:Thu, 16 Oct 2025 23:41:17 GMT pragma:no-cache server:nginx x-request-id:238-2638360 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#263
GET https://tx.fhir.org/r5/metadata HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 User-Agent: fhir/publisher
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:4221 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:02 GMT pragma:no-cache server:nginx x-request-id:238-2638403 {"resourceType" : "CapabilityStatement","id" : "FhirServer","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>Local User Conformance Statement</h2><p>FHIR v5.0.0 released 20250821042601.640Z. Server version 3.8.7 built 20250821042601.640Z</p><table class=\"grid\"><tr><th>Resource Type</th><th>Profile</th><th>Read</th><th>V-Read</th><th>Search</th><th>Update</th><th>Updates</th><th>Create</th><th>Delete</th><th>History</th></tr>\n</table>\n<p>Operations</p>\n<ul>\n <li>expand: see OperationDefinition/fso-expand</li>\n <li>lookup: see OperationDefinition/fso-lookup</li>\n <li>validate-code: see OperationDefinition/fso-validate-code</li>\n <li>batch-validate-code: see OperationDefinition/fso-batch-validate-code</li>\n <li>translate: see OperationDefinition/fso-translate</li>\n <li>closure: see OperationDefinition/fso-closure</li>\n <li>versions: see OperationDefinition/fso-versions</li>\n</ul>\n</div>"},"extension" : [{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-tests/FeatureDefinition/test-version"},{"url" : "value","valueCode" : "1.7.8"},{"extension" : [{"url" : "name","valueCode" : "mode"},{"url" : "value","valueCode" : "tx.fhir.org"}],"url" : "qualifier"}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"},{"extension" : [{"url" : "definition","valueCanonical" : "http://hl7.org/fhir/uv/tx-ecosystem/FeatureDefinition/CodeSystemAsParameter"},{"url" : "value","valueBoolean" : true}],"url" : "http://hl7.org/fhir/uv/application-feature/StructureDefinition/feature"}],"url" : "http://tx.fhir.org/r5/CapabilityStatement/tx","version" : "5.0.0-3.8.7","name" : "FHIRReferenceServer","title" : "FHIR Reference Server Conformance Statement","status" : "active","date" : "2025-10-16T23:42:02.568Z","contact" : [{"telecom" : [{"system" : "other","value" : "http://healthintersections.com.au/"}]}],"description" : "Standard Conformance Statement for the open source Reference FHIR Server provided by Health Intersections","kind" : "instance","instantiates" : ["http://hl7.org/fhir/CapabilityStatement/terminology-server","http://hl7.org/fhir/CapabilityStatement/terminology-server"],"software" : {"name" : "HealthIntersections Server","version" : "3.8.7","releaseDate" : "2025-08-21T04:26:01.640Z"},"implementation" : {"description" : "FHIR Server running at http://tx.fhir.org/r5","url" : "http://tx.fhir.org/r5"},"fhirVersion" : "5.0.0","format" : ["application/fhir+xml","application/fhir+json"],"rest" : [{"mode" : "server","security" : {"cors" : true},"resource" : [{"type" : "CodeSystem","interaction" : [{"code" : "read","documentation" : "Read a code system"},{"code" : "search-type","documentation" : "Search the code systems. Not that there a few major code systems that are not available through this API (SCT, LOINC etc)"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-validate-code"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/CodeSystem-lookup"}]},{"type" : "ValueSet","interaction" : [{"code" : "read","documentation" : "Read a ValueSet"},{"code" : "search-type","documentation" : "Search the value sets"}],"operation" : [{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-validate-code"},{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"}]}],"interaction" : [{"code" : "transaction"}],"operation" : [{"name" : "expand","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-expand"},{"name" : "lookup","definition" : "http://hl7.org/fhir/OperationDefinition/ValueSet-lookup"},{"name" : "validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-validate-code"},{"name" : "batch-validate-code","definition" : "http://hl7.org/fhir/OperationDefinition/Resource-batch-validate-code"},{"name" : "translate","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-translate"},{"name" : "closure","definition" : "http://hl7.org/fhir/OperationDefinition/ConceptMap-closure"},{"name" : "versions","definition" : "http://tx.fhir.org/r5/OperationDefinition/fso-versions"}]}]}
#264
GET https://tx.fhir.org/r5/metadata?mode=terminology HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 User-Agent: fhir/publisher
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POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"aed73e21-0736-41f6-ae03-c4548fe44d94"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":false,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"53075003","display":"Distal phalanx of hallux"},{"code":"76986006","display":"Distal phalanx of second toe"},{"code":"65258003","display":"Distal phalanx of third toe"},{"code":"54333003","display":"Distal phalanx of fourth toe"},{"code":"10770001","display":"Distal phalanx of fifth toe"},{"code":"363670009","display":"Interphalangeal joint structure of great toe"},{"code":"371216008","display":"Distal interphalangeal joint of second toe"},{"code":"371219001","display":"Distal interphalangeal joint of third toe"},{"code":"371205001","display":"Distal interphalangeal joint of fourth toe"},{"code":"371203008","display":"Distal interphalangeal joint of fifth toe"},{"code":"371292009","display":"Proximal interphalangeal joint of second toe"},{"code":"371255009","display":"Proximal interphalangeal joint of third toe"},{"code":"371288002","display":"Proximal interphalangeal joint of fourth toe"},{"code":"371284000","display":"Proximal interphalangeal joint of fifth toe"},{"code":"67169006","display":"Head of first metatarsal bone"},{"code":"9677004","display":"Head of second metatarsal bone"},{"code":"46971007","display":"Head of third metatarsal bone"},{"code":"3134008","display":"Head of fourth metatarsal bone"},{"code":"71822005","display":"Head of fifth metatarsal bone"},{"code":"89221001","display":"Base of first metatarsal bone"},{"code":"90894004","display":"Base of second metatarsal bone"},{"code":"89995006","display":"Base of third metatarsal bone"},{"code":"15368009","display":"Base of fourth metatarsal bone"},{"code":"30980004","display":"Base of fifth metatarsal bone"},{"code":"38607000","display":"Styloid process of fifth metatarsal bone"},{"code":"2979003","display":"Medial cuneiform bone"},{"code":"19193007","display":"Intermediate cuneiform bone"},{"code":"67411009","display":"Lateral cuneiform bone"},{"code":"81012005","display":"Bone structure of cuboid"},{"code":"75772009","display":"Bone structure of navicular"},{"code":"67453005","display":"Bone structure of talus"},{"code":"80144004","display":"Bone structure of calcaneum"},{"code":"6417001","display":"Medial malleolus"},{"code":"113225006","display":"Lateral malleolus of fibula"},{"code":"22457002","display":"Head of fibula"},{"code":"45879002","display":"Tibial tuberosity"},{"code":"122474001","display":"Medial condyle of femur"},{"code":"122475000","display":"Lateral condyle of femur"},{"code":"69030007","display":"Ischial tuberosity"},{"code":"29850006","display":"Iliac crest"}]}]}}}]}
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#266
GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fhl7.org%2Ffhir%2FValueSet%2Fsecurity-label-data-examples&version=6.0.0-ballot3 HTTP/1.0 User-Agent: hapi-fhir-tooling-client Accept: application/fhir+json
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#267
GET https://tx.fhir.org/r5/ValueSet?_format=json&url=http%3A%2F%2Fhl7.org%2Ffhir%2FValueSet%2Fsecurity-label-event-examples&version=6.0.0-ballot3 HTTP/1.0 User-Agent: hapi-fhir-tooling-client Accept: application/fhir+json
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:296 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:11 GMT pragma:no-cache server:nginx x-request-id:238-2638407 {"resourceType" : "Bundle","id" : "85a7bd40-02b5-403e-9be0-ba66011e1c","meta" : {"lastUpdated" : "2025-10-16T23:42:11.083Z"},"type" : "searchset","total" : 0,"link" : [{"relation" : "self","url" : "ValueSet?&url=http://hl7.org/fhir/ValueSet/security-label-event-examples&version=6.0.0-ballot3"}]}
#268
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122555007","display":"Venous blood specimen"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1122 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:12 GMT last-modified:Thu, 16 Oct 2025 23:42:12 GMT pragma:no-cache server:nginx x-request-id:238-2638410 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122555007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Venous blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122555007","display" : "Venous blood specimen"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#122555007 (\"Venous blood specimen\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#122555007\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#269
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13303-3","display":"HLA-A+B+C (class I) [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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#270
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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#271
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:01:01G","display":"HLA-A*01:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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#272
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1579 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:12 GMT last-modified:Thu, 16 Oct 2025 23:42:12 GMT pragma:no-cache server:nginx x-request-id:238-2638418 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "code","valueCode" : "GTR000000000.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://www.ncbi.nlm.nih.gov/gtr\"\r\n"}]}
#273
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:964 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:12 GMT last-modified:Thu, 16 Oct 2025 23:42:12 GMT pragma:no-cache server:nginx x-request-id:238-2638420 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"Gene studied [ID]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#274
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638422 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#275
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1572 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638425 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "code","valueCode" : "GTR000000000.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://www.ncbi.nlm.nih.gov/gtr\"\r\n"}]}
#276
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638427 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#277
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638429 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4931 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#278
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-A*01:02","display":"HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1776 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638431 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*01:02"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02 (\"HLA-A*01:02\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-A*01:02\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}
#279
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:983 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638433 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"Genotype display name\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#280
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1733 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638435 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-A:01:01G+HLA-A*01:02"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-A:01:01G+HLA-A*01:02\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#281
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://www.ncbi.nlm.nih.gov/gtr","code":"GTR000000000.0"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1579 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638438 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://www.ncbi.nlm.nih.gov/gtr"},{"name" : "code","valueCode" : "GTR000000000.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://www.ncbi.nlm.nih.gov/gtr' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://www.ncbi.nlm.nih.gov/gtr#GTR000000000.0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://www.ncbi.nlm.nih.gov/gtr\"\r\n"}]}
#282
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HGG00041","display":"HLA-B*15:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1771 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638440 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HGG00041"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HGG00041 (\"HLA-B*15:01:01G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HGG00041\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}
#283
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932","display":"HLA-B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:13 GMT last-modified:Thu, 16 Oct 2025 23:42:13 GMT pragma:no-cache server:nginx x-request-id:238-2638442 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4932"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4932 (\"HLA-B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4932\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#284
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932","display":"HLA-B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638444 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4932"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4932 (\"HLA-B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4932\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#285
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4932"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638446 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4932"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4932 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4932\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#286
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-B*57:01:01G","display":"HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1792 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638448 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-B*57:01:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G (\"HLA-B*57:01:01G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-B*57:01:01G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}
#287
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1747 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638450 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-B*15:01:01G+HLA-B*57:01:01G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#288
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23","code":"HLA-C*01:02:01G","display":"HLA-C*01:02:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1785 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638452 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-C*01:02:01G"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-C*01:02:01G (\"HLA-C*01:02:01G\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#HLA-C*01:02:01G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}
#289
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933","display":"HLA-C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638454 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4933"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4933 (\"HLA-C\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4933\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#290
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933","display":"HLA-C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638456 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4933"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4933 (\"HLA-C\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4933\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#291
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4933"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638458 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4933"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4933 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4933\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#292
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1754 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638460 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.23.0#HLA-C*01:02:01G+HLA-C*03:04:01G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#293
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.23"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1690 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:14 GMT last-modified:Thu, 16 Oct 2025 23:42:14 GMT pragma:no-cache server:nginx x-request-id:238-2638462 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "version","valueString" : "3.23"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.23' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.23# (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23#\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.23\"\r\n"}]}
#294
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1328 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:15 GMT last-modified:Thu, 16 Oct 2025 23:42:15 GMT pragma:no-cache server:nginx x-request-id:238-2638464 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}
#295
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69548-6","display":"Genetic variant assessment"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:998 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638473 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69548-6","display" : "Genetic variant assessment"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"Genetic variant assessment\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#296
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:945 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638476 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA9633-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#297
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"62374-4","display":"Human reference sequence assembly version"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1036 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638478 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "62374-4","display" : "Human reference sequence assembly version"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"Human reference sequence assembly version\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#298
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:946 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638480 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA14029-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#299
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1009 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638482 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence ID\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#300
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638485 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#301
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic state"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:959 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638487 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic state"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"Allelic state\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#302
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:960 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638490 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6706-1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#303
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Ref nucleotide"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:971 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638492 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Ref nucleotide"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"Ref nucleotide\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#304
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Alt allele"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:956 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638496 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Alt allele"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"Alt allele\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#305
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92822-6","display":"Genomic coord system"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:992 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638499 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92822-6","display" : "Genomic coord system"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"Genomic coord system\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#306
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:932 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:16 GMT last-modified:Thu, 16 Oct 2025 23:42:16 GMT pragma:no-cache server:nginx x-request-id:238-2638502 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30102-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#307
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1115 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:17 GMT last-modified:Thu, 16 Oct 2025 23:42:17 GMT pragma:no-cache server:nginx x-request-id:238-2638505 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA9633-4\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}
#308
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14029-5","display":"GRCh37"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1117 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:17 GMT last-modified:Thu, 16 Oct 2025 23:42:17 GMT pragma:no-cache server:nginx x-request-id:238-2638508 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14029-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh37"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Validate \"[http://loinc.org#LA14029-5 (\"GRCh37\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Check \"http://loinc.org#LA14029-5\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Filter \"LIST = LL1040-6\": Code \"LA14029-5\" found in http://loinc.org|2.81\r\n"}]}
#309
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1122 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:17 GMT last-modified:Thu, 16 Oct 2025 23:42:17 GMT pragma:no-cache server:nginx x-request-id:238-2638510 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Validate \"[http://loinc.org#LA6706-1 (\"heterozygous\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Check \"http://loinc.org#LA6706-1\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Filter \"LIST = LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}
#310
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1110 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:17 GMT last-modified:Thu, 16 Oct 2025 23:42:17 GMT pragma:no-cache server:nginx x-request-id:238-2638513 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30102-0 (\"\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30102-0\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}
#311
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:947 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:17 GMT last-modified:Thu, 16 Oct 2025 23:42:17 GMT pragma:no-cache server:nginx x-request-id:238-2638517 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6705-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#312
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6705-3","display":"homozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1116 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:17 GMT last-modified:Thu, 16 Oct 2025 23:42:17 GMT pragma:no-cache server:nginx x-request-id:238-2638519 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6705-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Homozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6705-3","display" : "homozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Validate \"[http://loinc.org#LA6705-3 (\"homozygous\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Check \"http://loinc.org#LA6705-3\"\r\n0 0: 0ms http://loinc.org/vs/LL381-5: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Filter \"LIST = LL381-5\": Code \"LA6705-3\" found in http://loinc.org|2.81\r\n"}]}
#313
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82120-7","display":"Allelic phase"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:952 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:19 GMT last-modified:Thu, 16 Oct 2025 23:42:19 GMT pragma:no-cache server:nginx x-request-id:238-2638521 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82120-7","display" : "Allelic phase"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"Allelic phase\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#314
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}],"text":"Genetic analysis report"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1302 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:19 GMT last-modified:Thu, 16 Oct 2025 23:42:19 GMT pragma:no-cache server:nginx x-request-id:238-2638523 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}],"text" : "Genetic analysis report"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}
#315
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"Present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2692 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:21 GMT last-modified:Thu, 16 Oct 2025 23:42:21 GMT pragma:no-cache server:nginx x-request-id:238-2638526 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA9633-4 ('Present')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA9633-4 ('Present')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA9633-4 (\"Present\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA9633-4\"\r\n"}]}
#316
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4","display":"Genetic analysis report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:989 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638528 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4","display" : "Genetic analysis report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51969-4 (\"Genetic analysis report\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#317
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81252-9","display":"Discrete genetic variant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:988 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638530 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81252-9","display" : "Discrete genetic variant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"Discrete genetic variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#318
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"30880","display":"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1608 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638532 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "30880"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#30880 (\"NM_014049.4(ACAD9):c.1249C>T (p.Arg417Cys)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#30880\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#319
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497","display":"ACAD9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1516 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638534 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:21497"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:21497 (\"ACAD9\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:21497\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#320
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638536 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#321
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638538 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#322
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:895 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638540 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#323
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1626 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638542 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#324
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638544 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#325
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:879 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:24 GMT last-modified:Thu, 16 Oct 2025 23:42:24 GMT pragma:no-cache server:nginx x-request-id:238-2638546 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#326
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:960 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638548 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6690-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Substitution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6690-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#327
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:948 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638550 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6683-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#328
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:960 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638552 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6706-1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#329
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497","display":"ACAD9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638555 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:21497"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:21497 (\"ACAD9\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:21497\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#330
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:21497"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638557 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:21497"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:21497 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:21497\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#331
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.128625063C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1418 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638559 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.128625063C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.128625063C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000003.11:g.128625063C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000003.11:g.128625063C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#332
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014049.4:c.1249C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638561 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014049.4:c.1249C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014049.4:c.1249C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_014049.4:c.1249C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_014049.4:c.1249C>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_014049.4:c.1249C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#333
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_054768.2:p.Arg417Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1398 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638563 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_054768.2:p.Arg417Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_054768.2:p.Arg417Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_054768.2:p.Arg417Cys\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_054768.2:p.Arg417Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#334
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6690-7","display":"Substitution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-ballot","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2558 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:25 GMT last-modified:Thu, 16 Oct 2025 23:42:25 GMT pragma:no-cache server:nginx x-request-id:238-2638566 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA6690-7 ('Substitution')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6690-7","display" : "Substitution"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6690-7 ('Substitution')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6690-7 (\"Substitution\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs|4.0.0-ballot: Check \"http://loinc.org#LA6690-7\"\r\n"}]}
#335
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6683-2","display":"Germline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1110 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638568 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6683-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Germline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Validate \"[http://loinc.org#LA6683-2 (\"Germline\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Check \"http://loinc.org#LA6683-2\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Filter \"LIST = LL378-1\": Code \"LA6683-2\" found in http://loinc.org|2.81\r\n"}]}
#336
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6706-1","display":"Heterozygous"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL381-5","name":"LOINCAnswersLL381-5","title":"LOINC Answer Codes for LL381-5","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1133 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638570 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6706-1"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Heterozygous"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6706-1","display" : "Heterozygous"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL381-5: Parameters: disp-lang=en-US, default-to-latest\r\n15 15: 15ms http://loinc.org/vs/LL381-5: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 15ms http://loinc.org/vs/LL381-5: Validate \"[http://loinc.org#LA6706-1 (\"Heterozygous\")]\"\r\n15 0: 15ms http://loinc.org/vs/LL381-5: Check \"http://loinc.org#LA6706-1\"\r\n15 0: 15ms http://loinc.org/vs/LL381-5: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 15ms http://loinc.org/vs/LL381-5: Filter \"LIST = LL381-5\": Code \"LA6706-1\" found in http://loinc.org|2.81\r\n"}]}
#337
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6668-3","display":"Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:947 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638572 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6668-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6668-3","display" : "Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6668-3 (\"Pathogenic\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6668-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#338
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0012624","display":"acyl-CoA dehydrogenase 9 deficiency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1660 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638574 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "code","valueCode" : "MONDO:0012624"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://purl.obolibrary.org/obo/mondo.owl#MONDO:0012624 (\"acyl-CoA dehydrogenase 9 deficiency\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://purl.obolibrary.org/obo/mondo.owl#MONDO:0012624\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://purl.obolibrary.org/obo/mondo.owl\"\r\n"}]}
#339
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"31934","display":"NM_000106.5(CYP2D6):c.886C>T (p.Arg296Cys)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1615 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638576 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "31934"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#31934 (\"NM_000106.5(CYP2D6):c.886C>T (p.Arg296Cys)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#31934\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#340
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638578 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#341
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:874 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638580 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#342
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:886 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638582 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#343
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.886C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1375 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:26 GMT last-modified:Thu, 16 Oct 2025 23:42:26 GMT pragma:no-cache server:nginx x-request-id:238-2638584 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.886C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.886C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.886C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000106.5:c.886C>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000106.5:c.886C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#344
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000097.3:p.Arg296Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1390 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638586 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000097.3:p.Arg296Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000097.3:p.Arg296Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000097.3:p.Arg296Cys\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000097.3:p.Arg296Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#345
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1616 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638588 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "38486"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#38486 (\"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#38486\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#346
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638590 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#347
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000106.5:c.1457G>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1380 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638592 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000106.5:c.1457G>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000106.5:c.1457G>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000106.5:c.1457G>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000106.5:c.1457G>C\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000106.5:c.1457G>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#348
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"293498008","display":"Debrisoquine adverse reaction (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1168 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638594 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "293498008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Debrisoquine adverse reaction"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "293498008","display" : "Debrisoquine adverse reaction (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#293498008 (\"Debrisoquine adverse reaction (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#293498008\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#349
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1184 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638596 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Check \"http://loinc.org#LA26423-6\"\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4049-4: Filter \"LIST = LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}
#350
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2342 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638598 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26423-6\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}
#351
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl","code":"C43359","display":"Group"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:913 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638600 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"},{"name" : "code","valueCode" : "C43359"},{"name" : "display","valueString" : "Group"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43359 (\"Group\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43359\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl| (from fhir.tx.support.r4#0.31.0)\" (content = fragment)\r\n"}]}
#352
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","code":"*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1550 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638602 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla#*2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla#*2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla\"\r\n"}]}
#353
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:27 GMT last-modified:Thu, 16 Oct 2025 23:42:27 GMT pragma:no-cache server:nginx x-request-id:238-2638604 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9*2*5\""},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9*2*5\" (\"CYP2C9 *2/*5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9*2*5\"\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#354
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623","display":"CYP2C9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638606 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2623 (\"CYP2C9\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2623\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#355
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663","display":"VKORC1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1510 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638608 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:23663"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:23663 (\"VKORC1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:23663\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#356
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623","display":"CYP2C9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638611 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2623 (\"CYP2C9\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2623\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#357
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2623"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638613 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:2623 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:2623\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#358
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663","display":"VKORC1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1517 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638615 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:23663"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:23663 (\"VKORC1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:23663\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#359
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:23663"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2551 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638617 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:23663"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:23663 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:23663\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#360
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"Warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1067 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638619 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "Warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"Warfarin\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#361
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:972 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638621 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA25390-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#362
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638624 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9*2*5\""},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9*2*5\" (\"CYP2C9 *2/*5\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9*2*5\"\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#363
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25390-8","display":"Rapid metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1846 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:28 GMT last-modified:Thu, 16 Oct 2025 23:42:28 GMT pragma:no-cache server:nginx x-request-id:238-2638627 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25390-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Rapid metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25390-8","display" : "Rapid metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA25390-8 (\"Rapid metabolizer\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA25390-8\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA25390-8\" found in http://loinc.org|2.81\r\n"}]}
#364
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:951 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638629 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6676-6 (\"Resistant\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6676-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#365
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6676-6","display":"Resistant"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1817 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638632 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6676-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Resistant"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6676-6","display" : "Resistant"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6676-6 (\"Resistant\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6676-6\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6676-6\" found in http://loinc.org|2.81\r\n"}]}
#366
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:948 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638634 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6576-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Positive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6576-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#367
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1079 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638636 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "10828004"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Positive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "10828004","display" : "Positive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#10828004 (\"Positive\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#10828004\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#368
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da","status":"active","compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1092 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638639 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Analysing\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: CodeSystem found: \"urn:ietf:bcp:13|\"\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Validate \"[#text/plain (\"\")]\" and infer system\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Check \"#text/plain\"\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n0 0: 0ms urn:uuid:ec120c77-d50d-45c8-90f0-cbec065631da: Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}
#369
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"inferSystem","valueBoolean":true},{"name":"code","valueCode":"text/plain"},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"mimetypes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"fhir"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/mimetypes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1024"}],"version":"6.0.0-ballot3","name":"MimeTypes","title":"Mime Types","status":"active","experimental":false,"date":"2025-04-01T12:16:37+11:00","publisher":"HL7 International - FHIR-Infrastructure","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all possible codes from BCP-13 (see http://tools.ietf.org/html/bcp13)","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"urn:ietf:bcp:13"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1158 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638641 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "urn:ietf:bcp:13"},{"name" : "code","valueCode" : "text/plain"},{"name" : "display","valueString" : "text/plain"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: CodeSystem found: \"urn:ietf:bcp:13|\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Validate \"[#text/plain (\"\")]\" and infer system\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Check \"#text/plain\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Inferred CodeSystem = \"urn:ietf:bcp:13\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: CodeSystem found: urn:ietf:bcp:13| for urn:ietf:bcp:13\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/mimetypes|6.0.0-ballot3: Code \"text/plain\" found in urn:ietf:bcp:13|\r\n"}]}
#370
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9*2*5\"","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638643 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9*2*5\""},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9*2*5\" (\"CYP2C9 *2/*5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9*2*5\"\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#371
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:945 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638645 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA19542-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#372
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19542-2","display":"Low risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1819 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638648 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19542-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Low risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19542-2","display" : "Low risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA19542-2 (\"Low risk\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA19542-2\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA19542-2\" found in http://loinc.org|2.81\r\n"}]}
#373
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"May need higher dosage than usual."}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":4}],"url":"http://hl7.org/fhir/ValueSet/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1396"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://hl7.org/fhir/CodeSystem/task-code","version":"6.0.0-ballot3"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablecodesystem"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/CodeSystem/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.4.1397"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"HL7 International","description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"valueSet":"http://hl7.org/fhir/ValueSet/task-code.html","content":"complete","concept":[{"code":"approve","display":"Activate/approve the focal resource","definition":"Take what actions are needed to transition the focus resource from 'draft' to 'active' or 'in-progress', as appropriate for the resource type. This may involve additing additional content, approval, validation, etc."},{"code":"fulfill","display":"Fulfill the focal request","definition":"Act to perform the actions described in the focus request. This might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events. The degree of fulfillment requested might be limited by Task.restriction."},{"code":"instantiate","display":"Instantiate the focal definition","definition":"Act to perform the actions defined in the focus definition resource (ActivityDefinition, PlanDefinition, Questionnaire, etc.) For PlanDefinition or ActivityDefinition, this might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events. For Questionnaire, this would result in a QuestionnaireResponse - and possibly resources constructed using data extracted from the response. The degree of fulfillment requested might be limited by Task.restriction."},{"code":"abort","display":"Mark the focal resource as no longer active","definition":"Abort, cancel or withdraw the focal resource, as appropriate for the type of resource."},{"code":"replace","display":"Replace the focal resource with the input resource","definition":"Replace the focal resource with the specified input resource"},{"code":"change","display":"Change the focal resource","definition":"Update the focal resource of the owning system to reflect the content specified as the Task.focus"},{"code":"suspend","display":"Suspend the focal resource","definition":"Transition the focal resource from 'active' or 'in-progress' to 'suspended'"},{"code":"resume","display":"Re-activate the focal resource","definition":"Transition the focal resource from 'suspended' to 'active' or 'in-progress' as appropriate for the resource type."}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2366 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:29 GMT last-modified:Thu, 16 Oct 2025 23:42:29 GMT pragma:no-cache server:nginx x-request-id:238-2638651 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "May need higher dosage than usual."}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Analysing\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: CodeSystem not found: \"http://hl7.org/fhir/CodeSystem/task-code|6.0.0-ballot3\"\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n31 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Check \"http://loinc.org#LA26423-6\"\r\n"}]}
#374
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1258 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638653 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n"}]}
#375
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","version":"137","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638656 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "version","valueString" : "137"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' version '137' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP|137#rs368949613\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP|137\"\r\n"}]}
#376
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81299-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:940 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638658 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81299-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant reported arrCGH [Ratio]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81299-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81299-0 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81299-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#377
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81300-6"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:925 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638660 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81300-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant [Length]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81300-6"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81300-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81300-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#378
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","version":"???","code":"38486","display":"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1791 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638663 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "38486"},{"name" : "version","valueString" : "???"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' version '???' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar|???#38486 (\"NM_000106.5(CYP2D6):c.1457G>C (p.Ser486Thr)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar|???#38486\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar|???\"\r\n"}]}
#379
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638665 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9 *2/*5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 *2/*5 (\"CYP2C9 *2/*5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9 *2/*5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#380
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:30 GMT last-modified:Thu, 16 Oct 2025 23:42:30 GMT pragma:no-cache server:nginx x-request-id:238-2638667 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9 *2/*5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 *2/*5 (\"CYP2C9 *2/*5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9 *2/*5\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#381
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9 *2/*5","display":"CYP2C9 *2/*5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638669 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9 *2/*5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 *2/*5 (\"CYP2C9 *2/*5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9 *2/*5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#382
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript ref sequence ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1006 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638671 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript ref sequence ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"Transcript ref sequence ID\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#383
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_022787.3","display":"NM_022787.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638673 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_022787.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_022787.3 (\"NM_022787.3\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_022787.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#384
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:982 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638675 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"Genomic ref allele [ID]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#385
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:989 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638677 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"Genomic alt allele [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#386
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"RCV000664188.1","display":"NM_022787.3(NMNAT1):c.[53A>G];[769G>A] AND Cone-rod dystrophy"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1654 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638679 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "RCV000664188.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#RCV000664188.1 (\"NM_022787.3(NMNAT1):c.[53A>G];[769G>A] AND Cone-rod dystrophy\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#RCV000664188.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#387
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6","display":"DNA change (c.HGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:970 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638681 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6","display" : "DNA change (c.HGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"DNA change (c.HGVS)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#388
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A","display":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:31 GMT last-modified:Thu, 16 Oct 2025 23:42:31 GMT pragma:no-cache server:nginx x-request-id:238-2638683 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"NM_022787.3:c.769G>A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#389
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.769G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1375 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638685 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.769G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.769G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.769G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_022787.3:c.769G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_022787.3:c.769G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#390
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G","display":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:889 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638687 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"NM_022787.3:c.53A>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#391
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_022787.3:c.53A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1378 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638690 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_022787.3:c.53A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_022787.3:c.53A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_022787.3:c.53A>G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_022787.3:c.53A>G\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_022787.3:c.53A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#392
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94076-7","display":"Mutations/Megabase [# Ratio] in Tumor"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1031 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638692 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94076-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Mutations/Megabase [# Ratio] in Tumor"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94076-7","display" : "Mutations/Megabase [# Ratio] in Tumor"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94076-7 (\"Mutations/Megabase [# Ratio] in Tumor\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94076-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#393
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:951 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638694 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26398-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#394
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81290-9","display":"Genomic DNA change (gHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:998 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638696 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81290-9","display" : "Genomic DNA change (gHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"Genomic DNA change (gHGVS)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#395
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T","display":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:922 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:32 GMT last-modified:Thu, 16 Oct 2025 23:42:32 GMT pragma:no-cache server:nginx x-request-id:238-2638698 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"NC_000007.13:g.140453136A>T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#396
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"13961","display":"Clinvar ID 13961"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1589 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638700 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "13961"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#13961 (\"Clinvar ID 13961\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#13961\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#397
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48005-3","display":"Amino acid change (pHGVS)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:995 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638702 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48005-3","display" : "Amino acid change (pHGVS)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"Amino acid change (pHGVS)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#398
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu","display":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:909 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638704 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"NP_004324.2:p.Val600Glu\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#399
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48018-6","display":"Gene studied ID"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:960 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638707 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48018-6","display" : "Gene studied ID"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"Gene studied ID\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#400
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097","display":"BRAF"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1505 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638709 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1097"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1097 (\"BRAF\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1097\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#401
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1129 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638711 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26398-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Check \"http://loinc.org#LA26398-0\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Filter \"LIST = LL4048-6\": Code \"LA26398-0\" found in http://loinc.org|2.81\r\n"}]}
#402
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.140453136A>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1418 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638714 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.140453136A>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.140453136A>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000007.13:g.140453136A>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000007.13:g.140453136A>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#403
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004324.2:p.Val600Glu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1390 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638716 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004324.2:p.Val600Glu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004324.2:p.Val600Glu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_004324.2:p.Val600Glu\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_004324.2:p.Val600Glu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#404
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097","display":"BRAF"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1505 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638718 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1097"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1097 (\"BRAF\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1097\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#405
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1097"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:33 GMT last-modified:Thu, 16 Oct 2025 23:42:33 GMT pragma:no-cache server:nginx x-request-id:238-2638720 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1097"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:1097 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:1097\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#406
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:987 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638722 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26811-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#407
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8","display":"Genetic variation clinical significance [Imp]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1055 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638724 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8","display" : "Genetic variation clinical significance [Imp]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"Genetic variation clinical significance [Imp]\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#408
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of Evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:971 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638726 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of Evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"Level of Evidence\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#409
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30200-2","display":"Very strong evidence pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1014 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638728 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30200-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Very strong evidence pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30200-2","display" : "Very strong evidence pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30200-2 (\"Very strong evidence pathogenic\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30200-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#410
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26398-0","display":"Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2284 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638730 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'; The provided code 'http://loinc.org#LA26398-0 ('Sequencing')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26398-0 ('Sequencing')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26398-0 (\"Sequencing\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26398-0\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26398-0\" not found in http://loinc.org|2.81\r\n"}]}
#411
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1165 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638732 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26811-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Computational analysis"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Check \"http://loinc.org#LA26811-2\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Filter \"LIST = LL4048-6\": Code \"LA26811-2\" found in http://loinc.org|2.81\r\n"}]}
#412
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26811-2","display":"Computational analysis"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2323 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638735 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'; The provided code 'http://loinc.org#LA26811-2 ('Computational analysis')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26811-2 ('Computational analysis')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26811-2 (\"Computational analysis\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26811-2\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26811-2\" not found in http://loinc.org|2.81\r\n"}]}
#413
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://hl7.org/fhir/sid/icd-10-cm","code":"C16.0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1043 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638737 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/sid/icd-10-cm"},{"name" : "code","valueCode" : "C16.0"},{"name" : "version","valueString" : "2024"},{"name" : "display","valueString" : "Malignant neoplasm of cardia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://hl7.org/fhir/sid/icd-10-cm","code" : "C16.0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://hl7.org/fhir/sid/icd-10-cm#C16.0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://hl7.org/fhir/sid/icd-10-cm#C16.0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://hl7.org/fhir/sid/icd-10-cm|2024 (from fhir.tx.support.r4#0.31.0)\" (content = complete)\r\n"}]}
#414
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:987 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:34 GMT last-modified:Thu, 16 Oct 2025 23:42:34 GMT pragma:no-cache server:nginx x-request-id:238-2638739 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"Genomic source class\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#415
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:945 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638741 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6684-0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#416
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975","display":"PIK3CA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638744 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8975"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8975 (\"PIK3CA\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8975\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#417
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G","display":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:899 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638746 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"NM_006218.4:c.3140A>G\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#418
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA change type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:958 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638748 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA change type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"DNA change type\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#419
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1565 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638750 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"substitution\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#420
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg","display":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:914 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638752 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"NP_006209.2:p.His1047Arg\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#421
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51958-7","display":"Transcript reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1022 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638754 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51958-7","display" : "Transcript reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"Transcript reference sequence [ID]\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#422
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006218.3","display":"NM_006218.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638756 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006218.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3 (\"NM_006218.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#423
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81258-6","display":"Sample VAF"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:978 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:35 GMT last-modified:Thu, 16 Oct 2025 23:42:35 GMT pragma:no-cache server:nginx x-request-id:238-2638758 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81258-6","display" : "Sample VAF"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"Sample VAF\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#424
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82121-5","display":"Allelic read depth"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:974 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638760 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82121-5","display" : "Allelic read depth"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"Allelic read depth\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#425
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6684-0","display":"Somatic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL378-1","name":"LOINCAnswersLL378-1","title":"LOINC Answer Codes for LL378-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1107 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638762 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6684-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Somatic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Validate \"[http://loinc.org#LA6684-0 (\"Somatic\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Check \"http://loinc.org#LA6684-0\"\r\n0 0: 0ms http://loinc.org/vs/LL378-1: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL378-1: Filter \"LIST = LL378-1\": Code \"LA6684-0\" found in http://loinc.org|2.81\r\n"}]}
#426
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975","display":"PIK3CA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638764 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8975"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8975 (\"PIK3CA\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8975\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#427
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8975"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638766 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8975"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:8975 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:8975\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#428
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.4:c.3140A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638769 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.4:c.3140A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.4:c.3140A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006218.4:c.3140A>G (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006218.4:c.3140A>G\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006218.4:c.3140A>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#429
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"substitution"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1572 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638771 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"substitution\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#430
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2709 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638773 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#431
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006209.2:p.His1047Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1395 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638776 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006209.2:p.His1047Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006209.2:p.His1047Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_006209.2:p.His1047Arg\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_006209.2:p.His1047Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#432
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989","display":"NRAS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1505 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638778 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7989"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7989 (\"NRAS\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7989\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#433
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T","display":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:882 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:36 GMT last-modified:Thu, 16 Oct 2025 23:42:36 GMT pragma:no-cache server:nginx x-request-id:238-2638780 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"NM_002524.4:c.34G>T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#434
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_002524.4","display":"NM_002524.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638783 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_002524.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_002524.4 (\"NM_002524.4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_002524.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#435
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989","display":"NRAS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638785 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7989"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7989 (\"NRAS\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7989\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#436
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7989"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638787 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7989"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7989 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7989\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#437
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002524.4:c.34G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1370 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638789 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002524.4:c.34G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002524.4:c.34G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_002524.4:c.34G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_002524.4:c.34G>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_002524.4:c.34G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#438
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712","display":"FBXW7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638791 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:16712"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:16712 (\"FBXW7\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:16712\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#439
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A","display":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:914 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638793 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"NM_001349798.2:c.1394G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#440
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His","display":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:924 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:37 GMT last-modified:Thu, 16 Oct 2025 23:42:37 GMT pragma:no-cache server:nginx x-request-id:238-2638795 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"NP_001336727.1:p.Arg465His\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#441
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001349798.2","display":"NM_001349798.2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1607 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638797 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001349798.2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001349798.2 (\"NM_001349798.2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001349798.2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#442
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712","display":"FBXW7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638800 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:16712"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:16712 (\"FBXW7\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:16712\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#443
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:16712"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638802 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:16712"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:16712 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:16712\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#444
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001349798.2:c.1394G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1403 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638804 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001349798.2:c.1394G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001349798.2:c.1394G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001349798.2:c.1394G>A\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001349798.2:c.1394G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#445
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_001336727.1:p.Arg465His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1413 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638806 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_001336727.1:p.Arg465His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_001336727.1:p.Arg465His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_001336727.1:p.Arg465His\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_001336727.1:p.Arg465His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#446
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133","display":"KMT2D"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638808 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7133"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7133 (\"KMT2D\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7133\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#447
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA","display":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:934 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638810 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"NM_003482.3:c.7900_7901delCA\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#448
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159","display":"deletion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1568 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:38 GMT last-modified:Thu, 16 Oct 2025 23:42:38 GMT pragma:no-cache server:nginx x-request-id:238-2638812 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000159 (\"deletion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000159\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#449
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003482.3","display":"NM_003482.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638814 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_003482.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_003482.3 (\"NM_003482.3\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_003482.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#450
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133","display":"KMT2D"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638816 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7133"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7133 (\"KMT2D\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7133\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#451
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7133"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638818 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7133"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7133 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7133\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#452
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003482.3:c.7900_7901delCA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1415 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638820 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003482.3:c.7900_7901delCA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003482.3:c.7900_7901delCA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_003482.3:c.7900_7901delCA\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_003482.3:c.7900_7901delCA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#453
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159","display":"deletion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1561 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638822 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000159 (\"deletion\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000159\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#454
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000159"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2709 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638824 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000159"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0000159 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0000159\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#455
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T","display":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:894 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638826 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"NM_006218.3:c.333G>T\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#456
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006218.3","display":"NM_006218.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638828 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006218.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3 (\"NM_006218.3\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006218.3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#457
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006218.3:c.333G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1383 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:39 GMT last-modified:Thu, 16 Oct 2025 23:42:39 GMT pragma:no-cache server:nginx x-request-id:238-2638830 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006218.3:c.333G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006218.3:c.333G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006218.3:c.333G>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006218.3:c.333G>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006218.3:c.333G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#458
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126","display":"IRS2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638832 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:6126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:6126 (\"IRS2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:6126\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#459
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T","display":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:892 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638834 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"NM_003749.2:c.3960C>T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#460
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003749.2","display":"NM_003749.2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638836 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_003749.2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_003749.2 (\"NM_003749.2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_003749.2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#461
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126","display":"IRS2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638838 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:6126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:6126 (\"IRS2\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:6126\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#462
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:6126"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638840 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:6126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:6126 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:6126\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#463
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003749.2:c.3960C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638842 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003749.2:c.3960C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003749.2:c.3960C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_003749.2:c.3960C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_003749.2:c.3960C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n94 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_003749.2:c.3960C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#464
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787","display":"CDKN2A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638844 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1787"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1787 (\"CDKN2A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1787\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#465
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:40 GMT last-modified:Thu, 16 Oct 2025 23:42:40 GMT pragma:no-cache server:nginx x-request-id:238-2638846 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#466
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:902 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638848 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#467
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000077.4","display":"NM_000077.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638850 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000077.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000077.4 (\"NM_000077.4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000077.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#468
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787","display":"CDKN2A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638852 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1787"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:1787 (\"CDKN2A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:1787\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#469
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:1787"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2553 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638854 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:1787"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n15 15: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:1787 (\"\")]\"\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:1787\"\r\n15 0: 15ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#470
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000077.4:c.9_32del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638856 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000077.4:c.9_32del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000077.4:c.9_32del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000077.4:c.9_32del (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000077.4:c.9_32del\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000077.4:c.9_32del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#471
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000068.1:p.Ala4_Pro11del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1418 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638858 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000068.1:p.Ala4_Pro11del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000068.1:p.Ala4_Pro11del\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000068.1:p.Ala4_Pro11del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#472
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949","display":"RECQL4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:41 GMT last-modified:Thu, 16 Oct 2025 23:42:41 GMT pragma:no-cache server:nginx x-request-id:238-2638860 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:9949"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:9949 (\"RECQL4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:9949\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#473
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638862 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#474
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:886 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638864 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#475
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004260.4","display":"NM_004260.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638866 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_004260.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_004260.4 (\"NM_004260.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_004260.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#476
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949","display":"RECQL4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1516 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638868 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:9949"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:9949 (\"RECQL4\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:9949\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#477
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:9949"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638870 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:9949"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:9949 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:9949\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#478
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004260.4:c.2086C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1380 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638872 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004260.4:c.2086C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004260.4:c.2086C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_004260.4:c.2086C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_004260.4:c.2086C>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_004260.4:c.2086C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#479
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004251.4:p.Arg696Cys"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1390 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:42 GMT last-modified:Thu, 16 Oct 2025 23:42:42 GMT pragma:no-cache server:nginx x-request-id:238-2638874 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004251.4:p.Arg696Cys"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004251.4:p.Arg696Cys"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_004251.4:p.Arg696Cys\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 79: 79ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_004251.4:p.Arg696Cys\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#480
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483","display":"RYR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638876 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10483 (\"RYR1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10483\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#481
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638878 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#482
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:883 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638880 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#483
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000540.2","display":"NM_000540.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638882 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000540.2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000540.2 (\"NM_000540.3\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000540.2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#484
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483","display":"RYR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1508 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638884 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10483 (\"RYR1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10483\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#485
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2551 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638886 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:10483 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:10483\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#486
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000540.3:c.4964G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1380 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:43 GMT last-modified:Thu, 16 Oct 2025 23:42:43 GMT pragma:no-cache server:nginx x-request-id:238-2638888 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000540.3:c.4964G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000540.3:c.4964G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000540.3:c.4964G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000540.3:c.4964G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000540.3:c.4964G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#487
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000531.2:p.Arg1655Leu"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1403 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638890 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000531.2:p.Arg1655Leu"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000531.2:p.Arg1655Leu"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000531.2:p.Arg1655Leu\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000531.2:p.Arg1655Leu\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#488
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519","display":"SACS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638892 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10519"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10519 (\"SACS\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10519\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#489
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:882 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638894 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#490
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014363.5","display":"NM_014363.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638896 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014363.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014363.5 (\"NM_014363.5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014363.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#491
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519","display":"SACS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638898 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10519"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10519 (\"SACS\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10519\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#492
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10519"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638900 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10519"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:10519 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:10519\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#493
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_014363.5:c.12118G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1385 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638902 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_014363.5:c.12118G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_014363.5:c.12118G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_014363.5:c.12118G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_014363.5:c.12118G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 79: 79ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_014363.5:c.12118G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#494
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086","display":"SLIT2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:44 GMT last-modified:Thu, 16 Oct 2025 23:42:44 GMT pragma:no-cache server:nginx x-request-id:238-2638904 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11086"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11086 (\"SLIT2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11086\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#495
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638906 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#496
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004787.3","display":"NM_004787.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638908 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_004787.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_004787.3 (\"NM_004787.3\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_004787.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#497
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086","display":"SLIT2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638910 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11086"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11086 (\"SLIT2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11086\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#498
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11086"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638912 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11086"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11086 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11086\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#499
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004787.3:c.1290C>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638914 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004787.3:c.1290C>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004787.3:c.1290C>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_004787.3:c.1290C>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_004787.3:c.1290C>A\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_004787.3:c.1290C>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#500
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100","display":"SMARCA4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1511 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638916 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11100"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11100 (\"SMARCA4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11100\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#501
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638918 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#502
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:886 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638920 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#503
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_003072.5","display":"NM_003072.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:45 GMT last-modified:Thu, 16 Oct 2025 23:42:45 GMT pragma:no-cache server:nginx x-request-id:238-2638922 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_003072.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_003072.5 (\"NM_003072.5\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_003072.5\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#504
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100","display":"SMARCA4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1518 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:46 GMT last-modified:Thu, 16 Oct 2025 23:42:46 GMT pragma:no-cache server:nginx x-request-id:238-2638924 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11100"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11100 (\"SMARCA4\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11100\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#505
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11100"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:46 GMT last-modified:Thu, 16 Oct 2025 23:42:46 GMT pragma:no-cache server:nginx x-request-id:238-2638926 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11100"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11100 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11100\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#506
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_003072.5:c.2372C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:46 GMT last-modified:Thu, 16 Oct 2025 23:42:46 GMT pragma:no-cache server:nginx x-request-id:238-2638928 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_003072.5:c.2372C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_003072.5:c.2372C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_003072.5:c.2372C>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_003072.5:c.2372C>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_003072.5:c.2372C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#507
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_003063.2:p.Ala791Val"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1390 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:46 GMT last-modified:Thu, 16 Oct 2025 23:42:46 GMT pragma:no-cache server:nginx x-request-id:238-2638930 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_003063.2:p.Ala791Val"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_003063.2:p.Ala791Val"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_003063.2:p.Ala791Val\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_003063.2:p.Ala791Val\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#508
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81695-9","display":"Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1135 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:47 GMT last-modified:Thu, 16 Oct 2025 23:42:47 GMT pragma:no-cache server:nginx x-request-id:238-2638932 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81695-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81695-9","display" : "Microsatellite instability [Interpretation] in Cancer specimen Qualitative"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81695-9 (\"Microsatellite instability [Interpretation] in Cancer specimen Qualitative\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81695-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#509
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:946 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:47 GMT last-modified:Thu, 16 Oct 2025 23:42:47 GMT pragma:no-cache server:nginx x-request-id:238-2638935 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA14122-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Stable"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA14122-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#510
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T","display":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:919 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638937 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"NC_000009.12:g.5073770G>T\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#511
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe","display":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:909 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638939 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"NP_004963.1:p.Val617Phe\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#512
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2","display":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1490 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638941 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "JAK2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#JAK2 (\"JAK2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#JAK2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#513
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.12:g.5073770G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1400 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638943 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.12:g.5073770G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.12:g.5073770G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000009.12:g.5073770G>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000009.12:g.5073770G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#514
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_004963.1:p.Val617Phe"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1390 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638945 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_004963.1:p.Val617Phe"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_004963.1:p.Val617Phe"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_004963.1:p.Val617Phe\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_004963.1:p.Val617Phe\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#515
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2","display":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1497 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638947 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "JAK2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#JAK2 (\"JAK2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#JAK2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#516
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"JAK2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2525 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638949 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "JAK2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#JAK2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#JAK2\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#517
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A","display":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:917 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:48 GMT last-modified:Thu, 16 Oct 2025 23:42:48 GMT pragma:no-cache server:nginx x-request-id:238-2638951 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"NC_000004.11:g.55972974T>A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#518
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His","display":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:909 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638953 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"NP_002244.1:p.Gln472His\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#519
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR","display":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1493 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638955 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "KDR"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#KDR (\"KDR\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#KDR\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#520
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000004.11:g.55972974T>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1413 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638957 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000004.11:g.55972974T>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000004.11:g.55972974T>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000004.11:g.55972974T>A\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000004.11:g.55972974T>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#521
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002244.1:p.Gln472His"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1398 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638959 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002244.1:p.Gln472His"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002244.1:p.Gln472His"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_002244.1:p.Gln472His (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_002244.1:p.Gln472His\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_002244.1:p.Gln472His\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#522
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR","display":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1486 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638961 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "KDR"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#KDR (\"KDR\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#KDR\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#523
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"KDR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638963 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "KDR"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#KDR (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#KDR\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#524
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del","display":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:972 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:49 GMT last-modified:Thu, 16 Oct 2025 23:42:49 GMT pragma:no-cache server:nginx x-request-id:238-2638965 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"NC_000002.12:g.211713666_211713668del\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#525
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4","display":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1501 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638967 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "ERBB4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#ERBB4 (\"ERBB4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#ERBB4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#526
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000002.12:g.211713666_211713668del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1468 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638969 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000002.12:g.211713666_211713668del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000002.12:g.211713666_211713668del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000002.12:g.211713666_211713668del\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000002.12:g.211713666_211713668del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#527
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4","display":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1501 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638971 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "ERBB4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#ERBB4 (\"ERBB4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#ERBB4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#528
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"ERBB4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2528 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638973 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "ERBB4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#ERBB4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#ERBB4\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#529
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"1193326","display":"Ruxolitinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1084 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638975 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "1193326"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "ruxolitinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "1193326","display" : "Ruxolitinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#1193326 (\"Ruxolitinib\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#1193326\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#530
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:954 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638977 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6677-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#531
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1820 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638980 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6677-4\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}
#532
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51963-7","display":"Medication assessed"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:975 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:50 GMT last-modified:Thu, 16 Oct 2025 23:42:50 GMT pragma:no-cache server:nginx x-request-id:238-2638982 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51963-7","display" : "Medication assessed"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"Medication assessed\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#533
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2259 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:51 GMT last-modified:Thu, 16 Oct 2025 23:42:51 GMT pragma:no-cache server:nginx x-request-id:238-2638984 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'; The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA14122-8\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA14122-8\" not found in http://loinc.org|2.81\r\n"}]}
#534
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA14122-8","display":"Stable"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2693 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:51 GMT last-modified:Thu, 16 Oct 2025 23:42:51 GMT pragma:no-cache server:nginx x-request-id:238-2638987 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA14122-8","display" : "Stable"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA14122-8 ('Stable')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA14122-8 (\"Stable\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA14122-8\"\r\n"}]}
#535
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1214 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:52 GMT last-modified:Thu, 16 Oct 2025 23:42:52 GMT pragma:no-cache server:nginx x-request-id:238-2638989 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26423-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Increase dose"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Check \"http://loinc.org#LA26423-6\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Filter \"LIST = LL4049-4\": Code \"LA26423-6\" found in http://loinc.org|2.81\r\n"}]}
#536
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"103","display":"mercaptopurine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1070 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:52 GMT last-modified:Thu, 16 Oct 2025 23:42:52 GMT pragma:no-cache server:nginx x-request-id:238-2638991 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "103"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "mercaptopurine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "103","display" : "mercaptopurine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#103 (\"mercaptopurine\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#103\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#537
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2363 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:52 GMT last-modified:Thu, 16 Oct 2025 23:42:52 GMT pragma:no-cache server:nginx x-request-id:238-2638993 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26423-6\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26423-6\" not found in http://loinc.org|2.81\r\n"}]}
#538
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"genotype display name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:976 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:52 GMT last-modified:Thu, 16 Oct 2025 23:42:52 GMT pragma:no-cache server:nginx x-request-id:238-2638995 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "genotype display name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"genotype display name\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#539
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1499 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:52 GMT last-modified:Thu, 16 Oct 2025 23:42:52 GMT pragma:no-cache server:nginx x-request-id:238-2638997 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4/*35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#540
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype Name"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:955 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:52 GMT last-modified:Thu, 16 Oct 2025 23:42:52 GMT pragma:no-cache server:nginx x-request-id:238-2638999 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype Name"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"Haplotype Name\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#541
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1496 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639001 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#542
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1607 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639003 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#543
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1494 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639005 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#544
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639007 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#545
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1613 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639009 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#546
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1503 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639011 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *35B\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#547
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1501 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639013 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#548
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1499 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:53 GMT last-modified:Thu, 16 Oct 2025 23:42:53 GMT pragma:no-cache server:nginx x-request-id:238-2639015 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4/*35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#549
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4/*35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1499 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:54 GMT last-modified:Thu, 16 Oct 2025 23:42:54 GMT pragma:no-cache server:nginx x-request-id:238-2639017 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4/*35B\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#550
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *35B"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1503 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:54 GMT last-modified:Thu, 16 Oct 2025 23:42:54 GMT pragma:no-cache server:nginx x-request-id:238-2639019 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *35B\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#551
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C9","display":"CYP2C9 *4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1494 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:54 GMT last-modified:Thu, 16 Oct 2025 23:42:54 GMT pragma:no-cache server:nginx x-request-id:238-2639021 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C9 (\"CYP2C9 *4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#552
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26423-6","display":"Increase dose"}],"text":"Any Increase does Recommendation Text from the provider"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":4}],"url":"http://hl7.org/fhir/ValueSet/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.1396"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://hl7.org/fhir/CodeSystem/task-code","version":"6.0.0-ballot3"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"task-code","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablecodesystem"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/CodeSystem/task-code","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.4.1397"}],"version":"6.0.0-ballot3","name":"TaskCode","title":"Task Codes","status":"active","experimental":false,"publisher":"HL7 International","description":"Codes indicating the type of action that is expected to be performed","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"valueSet":"http://hl7.org/fhir/ValueSet/task-code.html","content":"complete","concept":[{"code":"approve","display":"Activate/approve the focal resource","definition":"Take what actions are needed to transition the focus resource from 'draft' to 'active' or 'in-progress', as appropriate for the resource type. This may involve additing additional content, approval, validation, etc."},{"code":"fulfill","display":"Fulfill the focal request","definition":"Act to perform the actions described in the focus request. This might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events. The degree of fulfillment requested might be limited by Task.restriction."},{"code":"instantiate","display":"Instantiate the focal definition","definition":"Act to perform the actions defined in the focus definition resource (ActivityDefinition, PlanDefinition, Questionnaire, etc.) For PlanDefinition or ActivityDefinition, this might result in a 'more assertive' request (order for a plan or proposal, filler order for a placer order), but is intend to eventually result in events. For Questionnaire, this would result in a QuestionnaireResponse - and possibly resources constructed using data extracted from the response. The degree of fulfillment requested might be limited by Task.restriction."},{"code":"abort","display":"Mark the focal resource as no longer active","definition":"Abort, cancel or withdraw the focal resource, as appropriate for the type of resource."},{"code":"replace","display":"Replace the focal resource with the input resource","definition":"Replace the focal resource with the specified input resource"},{"code":"change","display":"Change the focal resource","definition":"Update the focal resource of the owning system to reflect the content specified as the Task.focus"},{"code":"suspend","display":"Suspend the focal resource","definition":"Transition the focal resource from 'active' or 'in-progress' to 'suspended'"},{"code":"resume","display":"Re-activate the focal resource","definition":"Transition the focal resource from 'suspended' to 'active' or 'in-progress' as appropriate for the resource type."}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2387 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:54 GMT last-modified:Thu, 16 Oct 2025 23:42:54 GMT pragma:no-cache server:nginx x-request-id:238-2639024 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'; The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26423-6","display" : "Increase dose"}],"text" : "Any Increase does Recommendation Text from the provider"}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26423-6 ('Increase dose')' was not found in the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: CodeSystem not found: \"http://hl7.org/fhir/CodeSystem/task-code|6.0.0-ballot3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Validate \"[http://loinc.org#LA26423-6 (\"Increase dose\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/task-code|6.0.0-ballot3: Check \"http://loinc.org#LA26423-6\"\r\n"}]}
#553
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"706687001","display":"Software (physical object)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1119 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:54 GMT last-modified:Thu, 16 Oct 2025 23:42:54 GMT pragma:no-cache server:nginx x-request-id:238-2639026 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "706687001"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Software"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "706687001","display" : "Software (physical object)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#706687001 (\"Software (physical object)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#706687001\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#554
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:54 GMT last-modified:Thu, 16 Oct 2025 23:42:54 GMT pragma:no-cache server:nginx x-request-id:238-2639029 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "14909"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#14909 (\"HLA-B*15:02\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#14909\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#555
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639031 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "14909"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#14909 (\"HLA-B*15:02\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#14909\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#556
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:955 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639033 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA19541-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#557
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2002","display":"Carbamazepine"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1078 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639035 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2002"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "carbamazepine"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2002","display" : "Carbamazepine"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2002 (\"Carbamazepine\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2002\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#558
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA19541-4","display":"High risk"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1822 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639038 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA19541-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "High risk"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA19541-4","display" : "High risk"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA19541-4 (\"High risk\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA19541-4\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA19541-4\" found in http://loinc.org|2.81\r\n"}]}
#559
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"14909","display":"HLA-B*15:02"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639040 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "14909"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#14909 (\"HLA-B*15:02\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#14909\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#560
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://loinc.org","code":"57979-7","display":"HLA-B*15:02 [Presence]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1763 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639042 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57979-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-B*15:02 [Presence]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://loinc.org","code" : "57979-7","display" : "HLA-B*15:02 [Presence]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\"), http://loinc.org#57979-7 (\"HLA-B*15:02 [Presence]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#57979-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"57979-7\" found in http://loinc.org|2.81\r\n"}]}
#561
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"51969-4"},{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"report-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"}],"url":"http://hl7.org/fhir/ValueSet/report-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.233"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.228"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.116"}],"version":"6.0.0-ballot3","name":"LOINCDiagnosticReportCodes","title":"LOINC Diagnostic Report Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes LOINC codes that relate to Diagnostic Observations.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:3174 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639045 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51969-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic analysis report"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated; The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "51969-4"},{"system" : "http://example.org/hgsc.bcm.edu/lab-test-codes/","code" : "emerge-seq-ngs-pnl"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl' was not found in the value set 'http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[1].code"],"expression" : ["CodeableConcept.coding[1].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["CodeableConcept.coding[1].system"],"expression" : ["CodeableConcept.coding[1].system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Validate \"[http://loinc.org#51969-4 (\"\"), http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://loinc.org#51969-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Code \"51969-4\" found in http://loinc.org|2.81\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/report-codes|6.0.0-ballot3: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n"}]}
#562
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1581 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639047 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "638797"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#638797 (\"CYP2C19*2/*2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#638797\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#563
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:55 GMT last-modified:Thu, 16 Oct 2025 23:42:55 GMT pragma:no-cache server:nginx x-request-id:238-2639049 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "638797"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#638797 (\"CYP2C19*2/*2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#638797\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#564
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639051 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2621"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2621 (\"CYP2C19\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2621\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#565
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639053 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2621"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:2621 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:2621\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#566
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2621","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639055 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2621"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2621 (\"CYP2C19\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2621\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#567
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10","display":"b37 Chr10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1589 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639057 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"b37 Chr10\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#568
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1006 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639059 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30102-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#569
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1505 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639061 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:262 (\"CYP2C19\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:262\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#570
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2537 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639063 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:262 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:262\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#571
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:262","display":"CYP2C19"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639065 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:262 (\"CYP2C19\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:262\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#572
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639067 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002073 (\"wild type\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002073\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#573
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30102-0","display":"1-based character counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1186 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639069 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30102-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "1-based character counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30102-0 (\"1-based character counting\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30102-0\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30102-0\" found in http://loinc.org|2.81\r\n"}]}
#574
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:56 GMT last-modified:Thu, 16 Oct 2025 23:42:56 GMT pragma:no-cache server:nginx x-request-id:238-2639071 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002073 (\"wild type\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002073\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#575
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002073"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2701 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:57 GMT last-modified:Thu, 16 Oct 2025 23:42:57 GMT pragma:no-cache server:nginx x-request-id:238-2639073 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002073"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0002073 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0002073\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#576
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:898 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:57 GMT last-modified:Thu, 16 Oct 2025 23:42:57 GMT pragma:no-cache server:nginx x-request-id:238-2639075 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#577
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.10:g.96540410G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1405 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:57 GMT last-modified:Thu, 16 Oct 2025 23:42:57 GMT pragma:no-cache server:nginx x-request-id:238-2639077 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.10:g.96540410G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.10:g.96540410G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000010.10:g.96540410G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000010.10:g.96540410G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#578
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1562 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:57 GMT last-modified:Thu, 16 Oct 2025 23:42:57 GMT pragma:no-cache server:nginx x-request-id:238-2639079 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"wild type\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#579
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002","display":"wild type"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:57 GMT last-modified:Thu, 16 Oct 2025 23:42:57 GMT pragma:no-cache server:nginx x-request-id:238-2639081 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"wild type\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#580
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000002"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2701 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:57 GMT last-modified:Thu, 16 Oct 2025 23:42:57 GMT pragma:no-cache server:nginx x-request-id:238-2639083 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000002"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:1000002 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:1000002\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#581
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"32968","display":"clopidogrel"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1069 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639085 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "32968"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "clopidogrel"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "32968","display" : "clopidogrel"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#32968 (\"clopidogrel\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#32968\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#582
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:965 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639087 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA9657-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#583
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9657-3","display":"Poor metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1838 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639090 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9657-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Poor metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9657-3","display" : "Poor metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA9657-3 (\"Poor metabolizer\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA9657-3\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA9657-3\" found in http://loinc.org|2.81\r\n"}]}
#584
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"121243","display":"voriconazole"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1083 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639092 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "121243"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "voriconazole"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "121243","display" : "voriconazole"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#121243 (\"voriconazole\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#121243\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#585
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"2556","display":"citalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1069 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639094 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "2556"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "citalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "2556","display" : "citalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#2556 (\"citalopram\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#2556\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#586
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"321988","display":"escitalopram"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1083 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639096 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "321988"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "escitalopram"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "321988","display" : "escitalopram"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#321988 (\"escitalopram\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#321988\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#587
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"704","display":"amitriptyline"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1067 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:58 GMT last-modified:Thu, 16 Oct 2025 23:42:58 GMT pragma:no-cache server:nginx x-request-id:238-2639098 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "704"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "amitriptyline"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "704","display" : "amitriptyline"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#704 (\"amitriptyline\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#704\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#588
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:59 GMT last-modified:Thu, 16 Oct 2025 23:42:59 GMT pragma:no-cache server:nginx x-request-id:238-2639100 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#589
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.31096368G>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1408 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:59 GMT last-modified:Thu, 16 Oct 2025 23:42:59 GMT pragma:no-cache server:nginx x-request-id:238-2639102 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.31096368G>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.31096368G>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000016.9:g.31096368G>T\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000016.9:g.31096368G>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#590
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"11289","display":"warfarin"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1067 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:59 GMT last-modified:Thu, 16 Oct 2025 23:42:59 GMT pragma:no-cache server:nginx x-request-id:238-2639106 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "11289"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "warfarin"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "11289","display" : "warfarin"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#11289 (\"warfarin\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#11289\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#591
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:975 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:59 GMT last-modified:Thu, 16 Oct 2025 23:42:59 GMT pragma:no-cache server:nginx x-request-id:238-2639108 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA25391-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#592
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA25391-6","display":"Normal metabolizer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1849 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:42:59 GMT last-modified:Thu, 16 Oct 2025 23:42:59 GMT pragma:no-cache server:nginx x-request-id:238-2639111 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA25391-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Normal metabolizer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA25391-6","display" : "Normal metabolizer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA25391-6 (\"Normal metabolizer\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA25391-6\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA25391-6\" found in http://loinc.org|2.81\r\n"}]}
#593
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"638797","display":"CYP2C19*2/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:00 GMT last-modified:Thu, 16 Oct 2025 23:43:00 GMT pragma:no-cache server:nginx x-request-id:238-2639113 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "638797"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#638797 (\"CYP2C19*2/*2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#638797\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#594
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84414-2","display":"Haplotype name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1326 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:00 GMT last-modified:Thu, 16 Oct 2025 23:43:00 GMT pragma:no-cache server:nginx x-request-id:238-2639115 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84414-2","display" : "Haplotype name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"Haplotype name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#57290-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#595
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ebi.ac.uk/ipd/imgt/hla","version":"3.31.0","code":"HLA-A*03:01:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1795 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:00 GMT last-modified:Thu, 16 Oct 2025 23:43:00 GMT pragma:no-cache server:nginx x-request-id:238-2639118 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ebi.ac.uk/ipd/imgt/hla"},{"name" : "code","valueCode" : "HLA-A*03:01:01:01"},{"name" : "version","valueString" : "3.31.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ebi.ac.uk/ipd/imgt/hla' version '3.31.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0#HLA-A*03:01:01:01\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ebi.ac.uk/ipd/imgt/hla|3.31.0\"\r\n"}]}
#596
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639120 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#597
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639122 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:4931 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:4931\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#598
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:4931","display":"HLA-A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639124 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:4931"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:4931 (\"HLA-A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:4931\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#599
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"84413-4","display":"Genotype display name"},{"system":"http://loinc.org","code":"57290-9","display":"HLA-A [Type] by High resolution"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1349 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639126 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "57290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type] by High resolution"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "84413-4","display" : "Genotype display name"},{"system" : "http://loinc.org","code" : "57290-9","display" : "HLA-A [Type] by High resolution"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"Genotype display name\"), http://loinc.org#57290-9 (\"HLA-A [Type] by High resolution\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#57290-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#600
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639128 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.31.0#HLA-A*03:01:01:01+HLA-A*30:01:01\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#601
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:870 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639130 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#602
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639132 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#603
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639134 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#604
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881","display":"NOTCH1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:01 GMT last-modified:Thu, 16 Oct 2025 23:43:01 GMT pragma:no-cache server:nginx x-request-id:238-2639136 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7881"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7881 (\"NOTCH1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7881\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#605
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:964 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639138 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21262-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#606
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000009.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639140 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000009.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000009.11\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#607
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:902 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639142 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#608
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1383 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639144 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_060087.3:p.A1931T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#609
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1380 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639146 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_017617.5:c.5791G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#610
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881","display":"NOTCH1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639148 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7881"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7881 (\"NOTCH1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7881\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#611
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7881"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639150 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7881"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7881 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7881\"\r\n16 16: 16ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#612
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21262-3","display":"Chromosome 9"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1144 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:02 GMT last-modified:Thu, 16 Oct 2025 23:43:02 GMT pragma:no-cache server:nginx x-request-id:238-2639152 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21262-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 9"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21262-3 (\"Chromosome 9\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21262-3\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21262-3\" found in http://loinc.org|2.81\r\n"}]}
#613
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000009.11:g.139395147C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1418 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639154 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000009.11:g.139395147C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000009.11:g.139395147C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000009.11:g.139395147C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000009.11:g.139395147C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#614
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:863 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639156 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#615
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639158 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#616
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:878 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639160 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#617
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777","display":"ZFHX3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1503 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639162 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:777"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:777 (\"ZFHX3\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:777\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#618
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:960 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639164 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21269-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#619
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000016.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639166 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000016.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000016.9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#620
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:03 GMT last-modified:Thu, 16 Oct 2025 23:43:03 GMT pragma:no-cache server:nginx x-request-id:238-2639168 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#621
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1378 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639170 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_008816.3:p.G585S\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#622
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639172 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006885.4:c.1753G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#623
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777","display":"ZFHX3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1510 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639174 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:777"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:777 (\"ZFHX3\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:777\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#624
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:777"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2545 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639176 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:777"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:777 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:777\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#625
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21269-8","display":"Chromosome 16"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1147 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639178 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21269-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 16"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21269-8 (\"Chromosome 16\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21269-8\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21269-8\" found in http://loinc.org|2.81\r\n"}]}
#626
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.9:g.72992292C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1400 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639180 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.9:g.72992292C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.9:g.72992292C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000016.9:g.72992292C>T\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000016.9:g.72992292C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#627
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235","display":"MSH2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1505 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639182 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7235"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7235 (\"MSH2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7235\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#628
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"1780982","display":"NM_000251.3(MSH2):c.1832del (p.Val611fs)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1619 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639184 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "1780982"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#1780982 (\"NM_000251.3(MSH2):c.1832del (p.Val611fs)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#1780982\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#629
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235","display":"MSH2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1508 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:04 GMT last-modified:Thu, 16 Oct 2025 23:43:04 GMT pragma:no-cache server:nginx x-request-id:238-2639186 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7235"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:7235 (\"MSH2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:7235\"\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#630
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:7235"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639188 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:7235"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:7235 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:7235\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#631
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:879 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639190 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#632
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1563 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639192 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"SNV\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#633
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:874 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639194 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#634
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028","display":"NTHL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639196 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8028"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8028 (\"NTHL1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8028\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#635
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"962538","display":"NM_002528.7(NTHL1):c.728G>A (p.Trp243Ter)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1610 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639198 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "962538"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#962538 (\"NM_002528.7(NTHL1):c.728G>A (p.Trp243Ter)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#962538\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#636
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:05 GMT last-modified:Thu, 16 Oct 2025 23:43:05 GMT pragma:no-cache server:nginx x-request-id:238-2639200 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#637
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1398 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639202 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_002519.2:p.Trp243Ter\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#638
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1563 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639204 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"SNV\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#639
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2701 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639206 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#640
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1375 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639208 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_002528.7:c.728G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#641
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028","display":"NTHL1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639210 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8028"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8028 (\"NTHL1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8028\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#642
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8028"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639212 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8028"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:8028 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:8028\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#643
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000016.10:g.2040196C>T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1408 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:06 GMT last-modified:Thu, 16 Oct 2025 23:43:06 GMT pragma:no-cache server:nginx x-request-id:238-2639214 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000016.10:g.2040196C>T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000016.10:g.2040196C>T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000016.10:g.2040196C>T\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000016.10:g.2040196C>T\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#644
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:870 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639216 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#645
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639218 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#646
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667","display":"insertion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639220 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000667 (\"insertion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000667\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#647
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:947 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639222 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#648
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355","display":"STAG2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639224 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11355"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11355 (\"STAG2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11355\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#649
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:957 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639226 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21276-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#650
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000023.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639228 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000023.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000023.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#651
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:998 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:07 GMT last-modified:Thu, 16 Oct 2025 23:43:07 GMT pragma:no-cache server:nginx x-request-id:238-2639230 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#652
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1375 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639232 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_006594.3:p.S1178*\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#653
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667","display":"insertion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1562 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639234 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0000667 (\"insertion\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0000667\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#654
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0000667"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2709 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639236 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0000667"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0000667 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0000667\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#655
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1475 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639238 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n62 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_006603.5:c.3530_3531insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#656
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355","display":"STAG2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1516 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639240 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11355"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11355 (\"STAG2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11355\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#657
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11355"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639242 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11355"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11355 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11355\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#658
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21276-3","display":"Chromosome X"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1144 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639244 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21276-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome X"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21276-3 (\"Chromosome X\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21276-3\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21276-3\" found in http://loinc.org|2.81\r\n"}]}
#659
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1538 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639246 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000023.10:g.123227930_123227931insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000023.10:g.123227930_123227931insGTGACTATTAATAT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#660
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:08 GMT last-modified:Thu, 16 Oct 2025 23:43:08 GMT pragma:no-cache server:nginx x-request-id:238-2639248 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#661
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:918 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639250 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#662
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882","display":"ATR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1508 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639252 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:882"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:882 (\"ATR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:882\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#663
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:964 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639254 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA21256-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#664
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000003.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639256 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000003.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000003.11\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#665
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:955 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639258 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#666
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1438 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639260 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001184.4:c.2878_2879insAGTAA\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#667
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882","display":"ATR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1501 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639262 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:882"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:882 (\"ATR\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:882\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#668
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:882"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2545 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:09 GMT last-modified:Thu, 16 Oct 2025 23:43:09 GMT pragma:no-cache server:nginx x-request-id:238-2639264 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:882"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:882 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:882\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#669
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA21256-5","display":"Chromosome 3"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL2938-0","name":"LOINCAnswersLL2938-0","title":"LOINC Answer Codes for LL2938-0","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1144 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639266 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA21256-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome 3"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Validate \"[http://loinc.org#LA21256-5 (\"Chromosome 3\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Check \"http://loinc.org#LA21256-5\"\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL2938-0: Filter \"LIST = LL2938-0\": Code \"LA21256-5\" found in http://loinc.org|2.81\r\n"}]}
#670
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000003.11:g.142269071_142269072insTTACT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1493 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639268 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000003.11:g.142269071_142269072insTTACT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000003.11:g.142269071_142269072insTTACT\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000003.11:g.142269071_142269072insTTACT\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#671
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:879 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639270 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#672
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:871 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639273 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#673
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236","display":"EGFR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639275 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3236"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3236 (\"EGFR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3236\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#674
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:891 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639277 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#675
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1390 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:10 GMT last-modified:Thu, 16 Oct 2025 23:43:10 GMT pragma:no-cache server:nginx x-request-id:238-2639279 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_005219.2:p.Leu858Arg\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#676
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1380 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639281 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_005228.4:c.2573T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#677
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236","display":"EGFR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639283 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3236"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3236 (\"EGFR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3236\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#678
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3236"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639286 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3236"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3236 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3236\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#679
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000007.13:g.55259515T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1413 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639288 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000007.13:g.55259515T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000007.13:g.55259515T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000007.13:g.55259515T>G\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000007.13:g.55259515T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#680
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261","display":"ROS1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1508 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639290 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10261"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10261 (\"ROS1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10261\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#681
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261","display":"ROS1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639292 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10261"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:10261 (\"ROS1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:10261\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#682
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:10261"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2551 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639294 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:10261"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:10261 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:10261\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#683
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26333-7","display":"Uncertain Significance"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:987 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639296 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26333-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Uncertain significance"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26333-7","display" : "Uncertain Significance"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26333-7 (\"Uncertain Significance\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26333-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#684
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4","display":"Associated phenotype"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:980 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:11 GMT last-modified:Thu, 16 Oct 2025 23:43:11 GMT pragma:no-cache server:nginx x-request-id:238-2639298 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4","display" : "Associated phenotype"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"Associated phenotype\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#685
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"699346009","display":"Hereditary cancer-predisposing syndrome (disorder)"}],"text":"Hereditary cancer-predisposing syndrome"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1240 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639300 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "699346009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Hereditary neoplastic syndrome"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "699346009","display" : "Hereditary cancer-predisposing syndrome (disorder)"}],"text" : "Hereditary cancer-predisposing syndrome"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#699346009 (\"Hereditary cancer-predisposing syndrome (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#699346009\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#686
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26332-9","display":"Likely Pathogenic"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:972 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639302 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26332-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Likely pathogenic"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26332-9","display" : "Likely Pathogenic"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26332-9 (\"Likely Pathogenic\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26332-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#687
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"93044-6","display":"Level of evidence"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:971 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639304 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "93044-6","display" : "Level of evidence"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"Level of evidence\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#688
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254637007","display":"Non-small cell lung cancer (disorder)"}],"text":"Non-small cell lung cancer"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1197 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639306 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254637007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Non-small cell lung cancer"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254637007","display" : "Non-small cell lung cancer (disorder)"}],"text" : "Non-small cell lung cancer"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#254637007 (\"Non-small cell lung cancer (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#254637007\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#689
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT04919811","display":"NCT04919811"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1525 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639308 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT04919811"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://clinicaltrials.gov#NCT04919811 (\"NCT04919811\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://clinicaltrials.gov#NCT04919811\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}
#690
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:996 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639310 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA6677-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#691
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to crizotinib"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1862 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:12 GMT last-modified:Thu, 16 Oct 2025 23:43:12 GMT pragma:no-cache server:nginx x-request-id:238-2639313 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to crizotinib"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6677-4\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}
#692
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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#693
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6677-4","display":"Responsive"}],"text":"cancer sensitive to pembrolizumab"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1865 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639318 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA6677-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Responsive"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6677-4","display" : "Responsive"}],"text" : "cancer sensitive to pembrolizumab"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n31 31: tx-op\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6677-4 (\"Responsive\")]\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://loinc.org#LA6677-4\"\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n31 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"LA6677-4\" found in http://loinc.org|2.81\r\n"}]}
#694
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48004-6"}],"text":"coding HGVS"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:947 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639320 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48004-6"}],"text" : "coding HGVS"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#695
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_017617.5:c.5791G>A","display":"NM_017617.5:c.5791G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:899 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639322 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_017617.5:c.5791G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_017617.5:c.5791G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_017617.5:c.5791G>A (\"NM_017617.5:c.5791G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_017617.5:c.5791G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#696
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_017617.5","display":"NM_017617.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639324 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_017617.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5 (\"NM_017617.5\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_017617.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#697
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583","display":"missense_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639327 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001583"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001583 (\"missense_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001583\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#698
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_060087.3:p.A1931T","display":"NP_060087.3:p.A1931T"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639329 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_060087.3:p.A1931T"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_060087.3:p.A1931T"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_060087.3:p.A1931T (\"NP_060087.3:p.A1931T\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_060087.3:p.A1931T\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#699
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583","display":"missense_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639332 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001583"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001583 (\"missense_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001583\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#700
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001583"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:13 GMT last-modified:Thu, 16 Oct 2025 23:43:13 GMT pragma:no-cache server:nginx x-request-id:238-2639334 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001583"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001583 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001583\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#701
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006885.4:c.1753G>A","display":"NM_006885.4:c.1753G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:899 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639336 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006885.4:c.1753G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006885.4:c.1753G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006885.4:c.1753G>A (\"NM_006885.4:c.1753G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006885.4:c.1753G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#702
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006885.4","display":"NM_006885.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639338 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006885.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4 (\"NM_006885.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006885.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#703
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_008816.3:p.G585S","display":"NP_008816.3:p.G585S"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:889 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639340 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_008816.3:p.G585S"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_008816.3:p.G585S"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_008816.3:p.G585S (\"NP_008816.3:p.G585S\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_008816.3:p.G585S\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#704
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del","display":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:892 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639343 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"NM_000251.3:c.1832del\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#705
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589","display":"frameshift_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1571 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639347 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001589"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001589 (\"frameshift_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001589\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#706
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000251.3:c.1832del"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1388 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639349 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000251.3:c.1832del"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000251.3:c.1832del"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000251.3:c.1832del (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000251.3:c.1832del\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000251.3:c.1832del\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#707
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589","display":"frameshift_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1571 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639351 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001589"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001589 (\"frameshift_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001589\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#708
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001589"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:14 GMT last-modified:Thu, 16 Oct 2025 23:43:14 GMT pragma:no-cache server:nginx x-request-id:238-2639353 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001589"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001589 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001589\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#709
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002528.7:c.728G>A","display":"NM_002528.7:c.728G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639355 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002528.7:c.728G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002528.7:c.728G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002528.7:c.728G>A (\"NM_002528.7:c.728G>A\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002528.7:c.728G>A\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#710
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587","display":"stop_gained"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1564 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639357 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001587"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001587 (\"stop_gained\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001587\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#711
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_002519.2:p.Trp243Ter","display":"NP_002519.2:p.Trp243Ter"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:902 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639359 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_002519.2:p.Trp243Ter"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_002519.2:p.Trp243Ter"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter (\"NP_002519.2:p.Trp243Ter\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_002519.2:p.Trp243Ter\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#712
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587","display":"stop_gained"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1564 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639361 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001587"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001587 (\"stop_gained\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001587\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#713
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001587"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2749 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639364 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001587"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001587 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001587\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#714
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_006603.5:c.3530_3531insGTGACTATTAATAT","display":"NM_006603.5:c.3530_3531insGTGACTATTAATAT"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:994 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639366 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_006603.5:c.3530_3531insGTGACTATTAATAT"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT (\"NM_006603.5:c.3530_3531insGTGACTATTAATAT\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_006603.5:c.3530_3531insGTGACTATTAATAT\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#715
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_006603.5","display":"NM_006603.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639368 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_006603.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5 (\"NM_006603.5\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_006603.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#716
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_006594.3:p.S1178*","display":"NP_006594.3:p.S1178*"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:887 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:15 GMT last-modified:Thu, 16 Oct 2025 23:43:15 GMT pragma:no-cache server:nginx x-request-id:238-2639370 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_006594.3:p.S1178*"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_006594.3:p.S1178*"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_006594.3:p.S1178* (\"NP_006594.3:p.S1178*\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_006594.3:p.S1178*\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#717
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001184.4:c.2878_2879insAGTAA","display":"NM_001184.4:c.2878_2879insAGTAA"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:942 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639372 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001184.4:c.2878_2879insAGTAA"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA (\"NM_001184.4:c.2878_2879insAGTAA\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001184.4:c.2878_2879insAGTAA\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#718
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001184.4","display":"NM_001184.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639374 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001184.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4 (\"NM_001184.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001184.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#719
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054","display":"loss_of_function_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639376 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO_0002054"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO_0002054 (\"loss_of_function_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO_0002054\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#720
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054","display":"loss_of_function_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639378 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO_0002054"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO_0002054 (\"loss_of_function_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO_0002054\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#721
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO_0002054"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2725 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639380 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO_0002054"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO_0002054 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO_0002054\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#722
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_005228.4:c.2573T>G","display":"NM_005228.4:c.2573T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:899 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639382 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_005228.4:c.2573T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_005228.4:c.2573T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_005228.4:c.2573T>G (\"NM_005228.4:c.2573T>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_005228.4:c.2573T>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#723
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_005219.2:p.Leu858Arg","display":"NP_005219.2:p.Leu858Arg"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:909 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639384 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_005219.2:p.Leu858Arg"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_005219.2:p.Leu858Arg"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg (\"NP_005219.2:p.Leu858Arg\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_005219.2:p.Leu858Arg\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#724
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886","display":"transcript_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:16 GMT last-modified:Thu, 16 Oct 2025 23:43:16 GMT pragma:no-cache server:nginx x-request-id:238-2639386 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001886"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001886 (\"transcript_fusion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001886\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#725
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886","display":"transcript_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639388 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001886"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001886 (\"transcript_fusion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001886\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#726
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001886"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2717 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639390 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001886"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001886 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001886\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#727
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:943 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639392 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26203-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "MSI-H"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26203-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#728
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"85147-7","display":"PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1069 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639395 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "85147-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "85147-7","display" : "PD-L1 by clone 22C3 in Tissue by Immune stain Report"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#85147-7 (\"PD-L1 by clone 22C3 in Tissue by Immune stain Report\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#85147-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#729
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635","display":"CD274"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1509 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639397 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:17635"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:17635 (\"CD274\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:17635\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#730
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635","display":"CD274"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1516 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639399 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:17635"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:17635 (\"CD274\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:17635\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#731
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:17635"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2551 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:17 GMT last-modified:Thu, 16 Oct 2025 23:43:17 GMT pragma:no-cache server:nginx x-request-id:238-2639401 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:17635"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:17635 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:17635\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#732
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2255 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:18 GMT last-modified:Thu, 16 Oct 2025 23:43:18 GMT pragma:no-cache server:nginx x-request-id:238-2639403 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'; The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA26203-2\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA26203-2\" not found in http://loinc.org|2.81\r\n"}]}
#733
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2261 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:18 GMT last-modified:Thu, 16 Oct 2025 23:43:18 GMT pragma:no-cache server:nginx x-request-id:238-2639405 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'; The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://loinc.org/vs/LL1971-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1971-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA6576-8\"\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA6576-8\" not found in http://loinc.org|2.81\r\n"}]}
#734
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26203-2","display":"MSI-H"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2689 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:19 GMT last-modified:Thu, 16 Oct 2025 23:43:19 GMT pragma:no-cache server:nginx x-request-id:238-2639409 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26203-2","display" : "MSI-H"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26203-2 ('MSI-H')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA26203-2 (\"MSI-H\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA26203-2\"\r\n"}]}
#735
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA6576-8","display":"Positive"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"sequence-phase-relationship-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipVS","title":"Sequence Phase Relationships","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"sequence-phase-relationship-cs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs","version":"4.0.0-ballot","name":"SequencePhaseRelationshipCS","title":"Sequence Phase Relationship Codes","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Code System for specific types of relationships","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"caseSensitive":true,"content":"complete","count":4,"concept":[{"code":"Cis","display":"Cis","definition":"Phase is in cis (same chromosome)"},{"code":"Trans","display":"Trans","definition":"Phase is in trans (different chromosomes)"},{"code":"Indeterminate","display":"Indeterminate","definition":"Phase is unable to be determined"},{"code":"Unknown","display":"Unknown","definition":"Phase is unknown"}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2696 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:19 GMT last-modified:Thu, 16 Oct 2025 23:43:19 GMT pragma:no-cache server:nginx x-request-id:238-2639412 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'; The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA6576-8","display" : "Positive"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA6576-8 ('Positive')' was not found in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/sequence-phase-relationship-cs|4.0.0-ballot\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Validate \"[http://loinc.org#LA6576-8 (\"Positive\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/sequence-phase-relationship-vs|4.0.0-ballot: Check \"http://loinc.org#LA6576-8\"\r\n"}]}
#736
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1040-6","name":"LOINCAnswersLL1040-6","title":"LOINC Answer Codes for LL1040-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1117 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639418 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Check \"http://loinc.org#LA26806-2\"\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1040-6: Filter \"LIST = LL1040-6\": Code \"LA26806-2\" found in http://loinc.org|2.81\r\n"}]}
#737
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"309529002","display":"Lung mass (finding)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1113 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639421 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "309529002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Lung mass"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "309529002","display" : "Lung mass (finding)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#309529002 (\"Lung mass (finding)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#309529002\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#738
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1563 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639423 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002007 (\"MNV\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#739
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1559 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639425 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000032"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000032 (\"delins\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000032\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#740
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"CNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1556 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639427 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"CNV\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#741
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"424993006","display":"Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1177 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639429 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "424993006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Adenocarcinoma of lung, stage IV"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "424993006","display" : "Adenocarcinoma of lung, stage IV (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#424993006 (\"Adenocarcinoma of lung, stage IV (disorder)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#424993006\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#742
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001565","display":"gene_fusion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1564 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639431 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001565 (\"gene_fusion\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001565\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#743
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001576","display":"transcript_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1578 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639433 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001576"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001576 (\"transcript_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001576\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#744
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48013-7","display":"Genomic reference sequence [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1013 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:20 GMT last-modified:Thu, 16 Oct 2025 23:43:20 GMT pragma:no-cache server:nginx x-request-id:238-2639435 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48013-7","display" : "Genomic reference sequence [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"Genomic reference sequence [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#745
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53034-5","display":"Allelic State"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:952 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639437 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53034-5","display" : "Allelic State"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"Allelic State\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#746
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5","display":"Genomic allele start-end"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:992 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639439 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5","display" : "Genomic allele start-end"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"Genomic allele start-end\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#747
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"398036000","display":"Familial hypercholesterolemia (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1186 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639441 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "398036000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Familial hypercholesterolemia (disorder)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "398036000","display" : "Familial hypercholesterolemia (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#398036000 (\"Familial hypercholesterolemia (disorder)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#398036000\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#748
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1574 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639443 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"copy_number_variation\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#749
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2709 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639445 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#750
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1574 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639447 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"copy_number_variation\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#751
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000022.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639449 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000022.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000022.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#752
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5489-1","name":"LOINCAnswersLL5489-1","title":"LOINC Answer Codes for LL5489-1","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1132 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:21 GMT last-modified:Thu, 16 Oct 2025 23:43:21 GMT pragma:no-cache server:nginx x-request-id:238-2639451 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Check \"http://loinc.org#LA26320-4\"\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL5489-1: Filter \"LIST = LL5489-1\": Code \"LA26320-4\" found in http://loinc.org|2.81\r\n"}]}
#753
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26320-4","display":"Maternal"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:952 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639453 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26320-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Maternal"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26320-4 (\"Maternal\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26320-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#754
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1150 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639455 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26426-9\"\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26426-9\" found in http://loinc.org|2.81\r\n"}]}
#755
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26426-9","display":"Directly measured"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:972 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639457 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26426-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Directly measured"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26426-9 (\"Directly measured\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26426-9\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#756
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000001.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639459 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000001.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000001.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#757
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036","display":"inversion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639461 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000036 (\"inversion\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000036\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#758
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2709 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639463 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:1000036 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:1000036\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#759
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000036","display":"inversion"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1569 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639465 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000036"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000036 (\"inversion\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000036\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#760
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"441262","display":"APOE1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1581 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639467 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "441262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#441262 (\"APOE1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#441262\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#761
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613","display":"APOE"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1502 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639470 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:613 (\"APOE\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:613\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#762
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2537 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:22 GMT last-modified:Thu, 16 Oct 2025 23:43:22 GMT pragma:no-cache server:nginx x-request-id:238-2639472 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:613 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:613\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#763
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:613","display":"APOE"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1502 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639475 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:613 (\"APOE\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:613\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#764
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"441262","display":"APOE1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1581 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639477 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "441262"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#441262 (\"APOE1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#441262\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#765
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00155","display":"CYP2D6*7.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639479 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00155"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00155 (\"CYP2D6*7.001\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00155\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#766
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625","display":"CYP2D6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639481 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2625"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2625 (\"CYP2D6\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2625\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#767
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639483 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2625"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:2625 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:2625\"\r\n16 16: 16ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#768
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:2625","display":"CYP2D6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639485 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:2625"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:2625 (\"CYP2D6\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:2625\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#769
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00126","display":"CYP2D6*1.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639487 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00126 (\"CYP2D6*1.001\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00126\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#770
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00155","display":"CYP2D6*7.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639489 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00155"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00155 (\"CYP2D6*7.001\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00155\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#771
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"PV00126","display":"CYP2D6*1.001"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639491 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "PV00126"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#PV00126 (\"CYP2D6*1.001\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#PV00126\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#772
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"18474-7","display":"HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1048 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639493 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "18474-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 Ag [Presence] in Tissue by Immune stain"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "18474-7","display" : "HER2 Ag [Presence] in Tissue by Immune stain"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#18474-7 (\"HER2 Ag [Presence] in Tissue by Immune stain\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#18474-7\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#773
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430","display":"ERBB2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:23 GMT last-modified:Thu, 16 Oct 2025 23:43:23 GMT pragma:no-cache server:nginx x-request-id:238-2639495 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3430"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3430 (\"ERBB2\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3430\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#774
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639497 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3430"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3430 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3430\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#775
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3430","display":"ERBB2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1513 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639499 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3430"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3430 (\"ERBB2\")]\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3430\"\r\n16 0: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#776
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"72382-5","display":"HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1052 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639501 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "72382-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HER2 [Units/volume] in Tissue by Immunoassay"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "72382-5","display" : "HER2 [Units/volume] in Tissue by Immunoassay"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#72382-5 (\"HER2 [Units/volume] in Tissue by Immunoassay\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#72382-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#777
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81291-7","display":"Variant ISCN"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:956 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639503 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81291-7","display" : "Variant ISCN"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"Variant ISCN\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#778
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX,t(9;22)(q34;q4)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1530 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639505 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX,t(9;22)(q34;q4)"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX,t(9;22)(q34;q4) (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX,t(9;22)(q34;q4)\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}
#779
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"92818009","display":"Chronic myeloid leukemia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1134 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639507 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "92818009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Chronic myeloid leukemia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "92818009","display" : "Chronic myeloid leukemia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#92818009 (\"Chronic myeloid leukemia\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#92818009\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#780
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"https://iscn.karger.com","code":"46,XX"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1482 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639509 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "https://iscn.karger.com"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "https://iscn.karger.com"},{"name" : "code","valueCode" : "46,XX"},{"name" : "message","valueString" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'https://iscn.karger.com' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[https://iscn.karger.com#46,XX (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"https://iscn.karger.com#46,XX\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"https://iscn.karger.com\"\r\n"}]}
#781
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775","display":"FMR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639511 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3775"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3775 (\"FMR1\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3775\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#782
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:24 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639513 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3775"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3775 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3775\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#783
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3775","display":"FMR1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1512 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:25 GMT last-modified:Thu, 16 Oct 2025 23:43:24 GMT pragma:no-cache server:nginx x-request-id:238-2639515 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3775"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3775 (\"FMR1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3775\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#784
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48001-2","display":"Cytogenetic (chromosome) location"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1012 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:25 GMT last-modified:Thu, 16 Oct 2025 23:43:25 GMT pragma:no-cache server:nginx x-request-id:238-2639517 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48001-2","display" : "Cytogenetic (chromosome) location"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"Cytogenetic (chromosome) location\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#785
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_002024.5","display":"NM_002024.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:25 GMT last-modified:Thu, 16 Oct 2025 23:43:25 GMT pragma:no-cache server:nginx x-request-id:238-2639519 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_002024.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_002024.5 (\"NM_002024.5\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_002024.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#786
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]","display":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1057 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:25 GMT last-modified:Thu, 16 Oct 2025 23:43:25 GMT pragma:no-cache server:nginx x-request-id:238-2639521 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#787
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1553 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:25 GMT last-modified:Thu, 16 Oct 2025 23:43:25 GMT pragma:no-cache server:nginx x-request-id:238-2639523 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10] (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_002024.5:c.-128_-69GGC[10]GGA[1]GGC[9]GGA[1]GGC[10]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#788
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"44054006","display":"Diabetes mellitus type 2 (disorder)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1157 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:26 GMT last-modified:Thu, 16 Oct 2025 23:43:26 GMT pragma:no-cache server:nginx x-request-id:238-2639525 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "44054006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Diabetes mellitus type II"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "44054006","display" : "Diabetes mellitus type 2 (disorder)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#44054006 (\"Diabetes mellitus type 2 (disorder)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#44054006\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#789
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565","display":"PABPN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:26 GMT last-modified:Thu, 16 Oct 2025 23:43:26 GMT pragma:no-cache server:nginx x-request-id:238-2639527 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8565 (\"PABPN1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8565\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#790
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2540 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:26 GMT last-modified:Thu, 16 Oct 2025 23:43:26 GMT pragma:no-cache server:nginx x-request-id:238-2639529 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:8565 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:8565\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#791
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:8565","display":"PABPN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1514 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:26 GMT last-modified:Thu, 16 Oct 2025 23:43:26 GMT pragma:no-cache server:nginx x-request-id:238-2639531 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:8565"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:8565 (\"PABPN1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:8565\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#792
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_004643.4","display":"NM_004643.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1588 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639533 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_004643.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_004643.4 (\"NM_004643.4\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_004643.4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#793
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]","display":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:904 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639535 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"NM_004643.3:c.3GGC[14]\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#794
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_004643.3:c.3GGC[14]"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1393 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639537 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_004643.3:c.3GGC[14]"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_004643.3:c.3GGC[14]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14] (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_004643.3:c.3GGC[14]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_004643.3:c.3GGC[14]\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#795
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/clinvar","code":"503634","display":"NM_004643.3(PABPN1):c.3GGC[11] (p.Ala11_Gly12insAlaAlaAlaAla)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1637 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639539 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/clinvar"},{"name" : "code","valueCode" : "503634"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/clinvar' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/clinvar#503634 (\"NM_004643.3(PABPN1):c.3GGC[11] (p.Ala11_Gly12insAlaAlaAlaAla)\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/clinvar#503634\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/clinvar\"\r\n"}]}
#796
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644","display":"AR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1507 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639541 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:644"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:644 (\"AR\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:644\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#797
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2545 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639543 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:644"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:644 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:644\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#798
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:644","display":"AR"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1500 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639545 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:644"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:644 (\"AR\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:644\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#799
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:866 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639547 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#800
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_000044.6:c.7G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1373 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:27 GMT last-modified:Thu, 16 Oct 2025 23:43:27 GMT pragma:no-cache server:nginx x-request-id:238-2639549 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_000044.6:c.7G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_000044.6:c.7G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_000044.6:c.7G>A (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_000044.6:c.7G>A\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_000044.6:c.7G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#801
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met","display":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:899 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:28 GMT last-modified:Thu, 16 Oct 2025 23:43:28 GMT pragma:no-cache server:nginx x-request-id:238-2639551 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"NP_000035.2:p.Val3Met\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#802
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NP_000035.2:p.Val3Met"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1380 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:28 GMT last-modified:Thu, 16 Oct 2025 23:43:28 GMT pragma:no-cache server:nginx x-request-id:238-2639553 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NP_000035.2:p.Val3Met"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NP_000035.2:p.Val3Met"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NP_000035.2:p.Val3Met (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NP_000035.2:p.Val3Met\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 78: 78ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NP_000035.2:p.Val3Met\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#803
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000044.3","display":"NM_000044.6"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1595 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:28 GMT last-modified:Thu, 16 Oct 2025 23:43:28 GMT pragma:no-cache server:nginx x-request-id:238-2639555 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000044.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000044.3 (\"NM_000044.6\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000044.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#804
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A","display":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:914 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:28 GMT last-modified:Thu, 16 Oct 2025 23:43:28 GMT pragma:no-cache server:nginx x-request-id:238-2639557 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"NC_000019.8:g.1171707G>A\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#805
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000019.8:g.1171707G>A"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1403 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:28 GMT last-modified:Thu, 16 Oct 2025 23:43:28 GMT pragma:no-cache server:nginx x-request-id:238-2639559 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000019.8:g.1171707G>A"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000019.8:g.1171707G>A"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000019.8:g.1171707G>A\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000019.8:g.1171707G>A\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#806
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2168 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:28 GMT last-modified:Thu, 16 Oct 2025 23:43:28 GMT pragma:no-cache server:nginx x-request-id:238-2639562 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://snomed.info/sct#444734003\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"444734003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}
#807
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"444734003","display":"Does not meet eligibility criteria for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1228 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639564 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "444734003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Does not meet eligibility criteria for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "444734003","display" : "Does not meet eligibility criteria for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#444734003 (\"Does not meet eligibility criteria for clinical trial\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#444734003\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#808
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT03131453","display":"NCT03131453"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1532 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639566 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT03131453"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://clinicaltrials.gov#NCT03131453 (\"NCT03131453\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://clinicaltrials.gov#NCT03131453\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}
#809
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"10828004","display":"Positive (qualifier value)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-interpretation","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"normative"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version","valueCode":"4.0.0"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":5}],"url":"http://hl7.org/fhir/ValueSet/observation-interpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.399"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.386"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.218"}],"version":"6.0.0-ballot3","name":"ObservationInterpretationCodes","title":"Observation Interpretation Codes","status":"active","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"A categorical assessment, providing a rough qualitative interpretation of the observation value, such as “normal”/ “abnormal”,”low” / “high”, “better” / “worse”, “susceptible” / “resistant”, “expected”/ “not expected”. The value set is intended to be for ANY use where coded representation of an interpretation is needed. \r\n \r\n Notes:\r\n \r\n This is being communicated in v2.x in OBX-8 (Observation Interpretation), in v3 in ObservationInterpretation (CWE) in R1 (Representative Realm) and in FHIR in Observation.interpretation. Historically these values come from the laboratory domain, and these codes are extensively used. The value set binding is extensible, so codes outside the value set that are needed for interpretation concepts (i.e. particular meanings) that are not included in the value set can be used, and these new codes may also be added to the value set and published in a future version.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation"}]}}},{"name":"tx-resource","resource":{"resourceType":"CodeSystem","id":"v3-ObservationInterpretation","language":"en","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"url":"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.5.83"}],"version":"3.0.0","name":"ObservationInterpretation","title":"ObservationInterpretation","status":"active","experimental":false,"date":"2019-03-20","publisher":"Health Level Seven International","contact":[{"telecom":[{"system":"url","value":"http://hl7.org"},{"system":"email","value":"hq@HL7.org"}]}],"description":"One or more codes providing a rough qualitative interpretation of the observation, such as \"normal\" / \"abnormal\", \"low\" / \"high\", \"better\" / \"worse\", \"resistant\" / \"susceptible\", \"expected\" / \"not expected\". The value set is intended to be for ANY use where coded representation of an interpretation is needed.","copyright":"This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html","caseSensitive":true,"hierarchyMeaning":"is-a","content":"complete","property":[{"extension":[{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry","valueCode":"antisymmetric"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity","valueCode":"transitive"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity","valueCode":"irreflexive"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable","valueBoolean":true},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind","valueCode":"Specializes"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName","valueString":"Generalizes"}],"code":"Specializes","description":"The child code is a more narrow version of the concept represented by the parent code. I.e. Every child concept is also a valid parent concept. Used to allow determination of subsumption. Must be transitive, irreflexive, antisymmetric.","type":"Coding"},{"extension":[{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry","valueCode":"antisymmetric"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity","valueCode":"transitive"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity","valueCode":"irreflexive"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable","valueBoolean":true},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind","valueCode":"Generalizes"},{"url":"http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName","valueString":"Specializes"}],"code":"Generalizes","description":"Inverse of Specializes. Only included as a derived relationship.","type":"Coding"},{"code":"internalId","uri":"http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id","description":"The internal identifier for the concept in the HL7 Access database repository.","type":"code"},{"code":"notSelectable","uri":"http://hl7.org/fhir/concept-properties#notSelectable","description":"Indicates that the code is abstract - only intended to be used as a selector for other concepts","type":"boolean"},{"code":"status","uri":"http://hl7.org/fhir/concept-properties#status","description":"A property that indicates the status of the concept. One of active, experimental, deprecated, or retired.","type":"code"},{"code":"deprecationDate","uri":"http://hl7.org/fhir/concept-properties#deprecationDate","description":"The date at which a concept was deprecated. Concepts that are deprecated but not inactive can still be used, but their use is discouraged.","type":"dateTime"},{"code":"subsumedBy","uri":"http://hl7.org/fhir/concept-properties#parent","description":"The concept code of a parent concept","type":"code"}],"concept":[{"code":"_GeneticObservationInterpretation","display":"GeneticObservationInterpretation","definition":"Codes that specify interpretation of genetic analysis, such as \"positive\", \"negative\", \"carrier\", \"responsive\", etc.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22646"}]},{"code":"_ObservationInterpretationChange","display":"ObservationInterpretationChange","definition":"Interpretations of change of quantity and/or severity. At most one of B or W and one of U or D allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21090"}]},{"code":"_ObservationInterpretationExceptions","display":"ObservationInterpretationExceptions","definition":"Technical exceptions resulting in the inability to provide an interpretation. At most one allowed. Does not imply normality or severity.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21091"}]},{"code":"_ObservationInterpretationNormality","display":"ObservationInterpretationNormality","definition":"Interpretation of normality or degree of abnormality (including critical or \"alert\" level). Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21092"}]},{"code":"_ObservationInterpretationSusceptibility","display":"ObservationInterpretationSusceptibility","definition":"Interpretations of anti-microbial susceptibility testing results (microbiology). At most one allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21093"}]},{"code":"EX","display":"outside threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21634"}]},{"code":"HM","display":"Hold for Medical Review","definition":"Hold for Medical Review\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23790"}]},{"code":"ObservationInterpretationDetection","display":"ObservationInterpretationDetection","definition":"Interpretations of the presence or absence of a component / analyte or organism in a test or of a sign in a clinical observation. In keeping with laboratory data processing practice, these concepts provide a categorical interpretation of the \"meaning\" of the quantitative value for the same observation.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22805"}]},{"code":"ObservationInterpretationExpectation","display":"ObservationInterpretationExpectation","definition":"Interpretation of the observed result taking into account additional information (contraindicators) about the patient's situation. Concepts in this category are mutually exclusive, i.e., at most one is allowed.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23723"}]},{"code":"OBX","display":"Interpretation qualifiers in separate OBX segments","definition":"Interpretation qualifiers in separate OBX segments\r\n\r\n*Usage Note:* This code is not intended for use in V3 artifacts. It is included in the code system to maintain alignment with the V2 Table 0078 \"Interpretation Codes.\"","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23789"}]},{"code":"ReactivityObservationInterpretation","display":"ReactivityObservationInterpretation","definition":"Interpretations of the presence and level of reactivity of the specified component / analyte with the reagent in the performed laboratory test.","property":[{"code":"notSelectable","valueBoolean":true},{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23568"}]},{"code":"CAR","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23559"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"Carrier","display":"Carrier","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This code is currently the same string as the print name for this concept and is inconsistent with the conventions being used for the other codes in the coding system, as it is a full word with initial capitalization, rather than an all upper case mnemonic. The recommendation from OO is to deprecate the code \"Carrier\" and to add \"CAR\" as the new active code representation for this concept.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"22647"},{"code":"subsumedBy","valueCode":"_GeneticObservationInterpretation"}]},{"code":"B","display":"Better","definition":"The current result or observation value has improved compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10215"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"D","display":"Significant change down","definition":"The current result has decreased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10218"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"U","display":"Significant change up","definition":"The current result has increased from the previous result for a quantitative observation (the change is significant as defined in the respective test procedure).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10217"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"W","display":"Worse","definition":"The current result or observation value has degraded compared to the previous result or observation value (the change is significant as defined in the respective test procedure).\r\n\r\n\\[Note: This can be applied to quantitative or qualitative observations.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10216"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationChange"}]},{"code":"<","display":"Off scale low","definition":"The result is below the minimum detection limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Below analytical limit, low off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10226"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":">","display":"Off scale high","definition":"The result is above the maximum quantifiable limit (the test procedure or equipment is the limiting factor).\r\n\r\nSynonyms: Above analytical limit, high off scale.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10227"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"AC","display":"Anti-complementary substances present","definition":"A valid result cannot be obtained for the specified component / analyte due to the presence of anti-complementary substances in the sample.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23564"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"IE","display":"Insufficient evidence","definition":"There is insufficient evidence that the species in question is a good target for therapy with the drug. A categorical interpretation is not possible.\r\n\r\n\\[Note: A MIC with \"IE\" and/or a comment may be reported (without an accompanying S, I or R-categorization).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23567"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"QCF","display":"Quality control failure","definition":"A result cannot be considered valid for the specified component / analyte or organism due to failure in the quality control testing component.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23565"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"TOX","display":"Cytotoxic substance present","definition":"A valid result cannot be obtained for the specified organism or cell line due to the presence of cytotoxic substances in the sample or culture.\r\n\r\n***Deprecation Comment:*** This code is being deprecated to match the status in V2 Table 0078 \"Interpretation Codes.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2016-11-10"},{"code":"internalId","valueCode":"23566"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationExceptions"}]},{"code":"A","display":"Abnormal","definition":"The result or observation value is outside the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10208"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"N","display":"Normal","definition":"The result or observation value is within the reference range or expected norm (as defined for the respective test procedure).\r\n\r\n\\[Note: Applies to numeric or non-numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10207"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationNormality"}]},{"code":"I","display":"Intermediate","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\\]\r\n\r\n\\[Note 3: This class also indicates a \"buffer zone,\" to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\\]\r\n\r\n\\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10221"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"MS","display":"moderately susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10222"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NCL","display":"No CLSI defined breakpoint","definition":"Use when not enough clinical trial data published by the Clinical and Laboratory Standards Institutes (CLSI) is available to establish the breakpoints for susceptible / intermediate and resistant.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23886"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"NS","display":"Non-susceptible","definition":"A category used for isolates for which only a susceptible interpretive criterion has been designated because of the absence or rare occurrence of resistant strains. Isolates that have MICs above or zone diameters below the value indicated for the susceptible breakpoint should be reported as non-susceptible.\r\n\r\nNOTE 1: An isolate that is interpreted as non-susceptible does not necessarily mean that the isolate has a resistance mechanism. It is possible that isolates with MICs above the susceptible breakpoint that lack resistance mechanisms may be encountered within the wild-type distribution subsequent to the time the susceptible-only breakpoint is set.\r\n\r\nNOTE 2: For strains yielding results in the \"nonsusceptible\" category, organism identification and antimicrobial susceptibility test results should be confirmed.\r\n\r\nSynonym: decreased susceptibility.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23557"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"R","display":"Resistant","definition":"Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic failure. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as resistant by applying the appropriate breakpoints in a defined phenotypic test system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10220"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"S","display":"Susceptible","definition":"Bacterial strain inhibited by in vitro concentration of an antimicrobial agent that is associated with a high likelihood of therapeutic success. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Synonym (earlier term): Sensitive Projects: ISO 20776-1, ISO 20776-2\r\n\r\n\\[Note 1: Bacterial strains are categorized as susceptible by applying the appropriate breakpoints in a defined phenotypic system.\\]\r\n\r\n\\[Note 2: This breakpoint can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10223"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"VS","display":"very susceptible","definition":"The patient is considered as carrier based on the testing results. A carrier is an individual who carries an altered form of a gene which can lead to having a child or offspring in future generations with a genetic disorder.\r\n\r\n***Deprecation Comment:*** This antimicrobial susceptibility test interpretation concept is recommended by OO to be deprecated as it is no longer recommended for use in susceptibility testing by CLSI (reference CLSI document M100-S22; Vol. 32 No.3; CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Second Informational Supplement. Jan 2012).","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2013-07-28"},{"code":"internalId","valueCode":"10224"},{"code":"subsumedBy","valueCode":"_ObservationInterpretationSusceptibility"}]},{"code":"AA","display":"Critical abnormal","definition":"The result or observation value is outside a reference range or expected norm at a level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\n\\[Note: Typically applies to non-numeric results. Analogous to critical/panic limits for numeric results.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10211"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"H","display":"High","definition":"The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Above high normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10210"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"L","display":"Low","definition":"The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).\r\n\r\nSynonym: Below low normal","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10209"},{"code":"subsumedBy","valueCode":"A"}]},{"code":"HH","display":"Critical high","definition":"The result for a quantitative observation is above a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Above upper panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10213"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"H>"},{"code":"subsumedBy","valueCode":"HU"}]},{"code":"LL","display":"Critical low","definition":"The result for a quantitative observation is below a reference level at which immediate action should be considered for patient safety (as defined for the respective test procedure).\r\n\r\nSynonym: Below lower panic limits.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"10212"},{"code":"subsumedBy","valueCode":"AA"},{"code":"subsumedBy","valueCode":"L<"},{"code":"subsumedBy","valueCode":"LU"}]},{"code":"HX","display":"above high threshold","definition":"The observation/test result is interpreted as being outside the inclusion range for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A positive result on a Hepatitis screening test.\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21636"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"LX","display":"below low threshold","definition":"The numeric observation/test result is interpreted as being below the low threshold value for a particular protocol within which the result is being reported.\r\n\r\n**Example:** A Total White Blood Cell Count falling below a protocol-defined threshold value of 3000/mm^3\r\n\r\n*Open Issue:* EX, HX, LX: These three concepts do not seem to meet a clear need in the vocabulary, and their use in observation interpretation appears likely to be covered by other existing concepts (e.g., A, H, L). The only apparent significant difference is their reference to use in protocols for exclusion of study subjects. These concepts/codes were proposed by RCRIM for use in the CTLaboratory message. They were submitted and approved in the November 2005 Harmonization cycle in proposal \"030103C\\_VOCAB\\_RCRIM\\_l\\_quade\\_RCRIM Obs Interp\\_20051028154455\". However, this proposal was not fully implemented in the vocabulary. The proposal recommended creation of the x\\_ClinicalResearchExclusion domain in ObservationInterpretation with a value set including those three concepts/codes, but there is no subdomain of that name or equivalent with a binding to either of the value sets that contain these concepts/codes. Members of the OO WG have recently attempted to contact members of RCRIM regarding these concepts, both by email and at the recent WGM in Atlanta, without response. It is felt by OO that the best course of action to take at this time is to add this comprehensive Open Issue rather than deprecate these three concepts at this time, until further discussion is held.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"21635"},{"code":"subsumedBy","valueCode":"EX"}]},{"code":"H>","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'H' and 'HH'.\\]\r\n\r\n*Deprecation Comment:* The code 'H>' is being deprecated in order to align with the use of the code 'HU' for \"Very high\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'H>' is non-preferred, as this code is deprecated and on track to be retired; use code 'HU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23560"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"HU","display":"Significantly high","definition":"A test result that is significantly higher than the reference (normal) or therapeutic interval, but has not reached the critically high value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23742"},{"code":"subsumedBy","valueCode":"H"}]},{"code":"E","display":"Equivocal","definition":"The test or procedure was successfully performed, but the results are borderline and can neither be declared positive / negative nor detected / not detected according to the current established criteria.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23732"},{"code":"subsumedBy","valueCode":"IND"}]},{"code":"L<","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.\r\n\r\n\\[Note: This level is situated between 'L' and 'LL'.\\]\r\n\r\n*Deprecation Comment:* The code 'L<' is being deprecated in order to align with the use of the code 'LU' for \"Very low\" in V2 Table 0078 \"Interpretation Codes\".\r\n\r\n\\[Note: The use of code 'L<' is non-preferred, as this code is deprecated and on track to be retired; use code 'LU' instead.","property":[{"code":"status","valueCode":"deprecated"},{"code":"deprecationDate","valueDateTime":"2015-03-23"},{"code":"internalId","valueCode":"23561"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"LU","display":"Significantly low","definition":"A test result that is significantly lower than the reference (normal) or therapeutic interval, but has not reached the critically low value and might need special attention, as defined by the laboratory or the clinician.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23743"},{"code":"subsumedBy","valueCode":"L"}]},{"code":"ND","display":"Not detected","definition":"The presence of the specified component / analyte, organism or clinical sign could not be determined within the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23563"},{"code":"subsumedBy","valueCode":"NEG"}]},{"code":"IND","display":"Indeterminate","definition":"The specified component / analyte, organism or clinical sign could neither be declared positive / negative nor detected / not detected by the performed test or procedure.\r\n\r\n*Usage Note:* For example, if the specimen was degraded, poorly processed, or was missing the required anatomic structures, then \"indeterminate\" (i.e. \"cannot be determined\") is the appropriate response, not \"equivocal\".","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22807"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"NEG","display":"Negative","definition":"An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.\r\n\r\n\\[Note: Negative does not necessarily imply the complete absence of the specified item.\\]","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22808"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"POS","display":"Positive","definition":"A presence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"22806"},{"code":"subsumedBy","valueCode":"ObservationInterpretationDetection"}]},{"code":"EXP","display":"Expected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Expected\" (e.g., presence of drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23724"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"UNE","display":"Unexpected","definition":"This result has been evaluated in light of known contraindicators. Once those contraindicators have been taken into account the result is determined to be \"Unexpected\" (e.g., presence of non-prescribed drugs in a patient that is taking prescription medication for pain management).","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23725"},{"code":"subsumedBy","valueCode":"ObservationInterpretationExpectation"}]},{"code":"DET","display":"Detected","definition":"The measurement of the specified component / analyte, organism or clinical sign above the limit of detection of the performed test or procedure.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23562"},{"code":"subsumedBy","valueCode":"POS"}]},{"code":"SYN-R","display":"Synergy - resistant","definition":"A category for isolates where the bacteria (e.g. enterococci) are not susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will not be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23621"},{"code":"subsumedBy","valueCode":"R"}]},{"code":"NR","display":"Non-reactive","definition":"An absence finding used to indicate that the specified component / analyte did not react measurably with the reagent.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23569"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"RR","display":"Reactive","definition":"A presence finding used to indicate that the specified component / analyte reacted with the reagent above the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23570"},{"code":"subsumedBy","valueCode":"ReactivityObservationInterpretation"}]},{"code":"WR","display":"Weakly reactive","definition":"A weighted presence finding used to indicate that the specified component / analyte reacted with the reagent, but below the reliably measurable limit of the performed test.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23571"},{"code":"subsumedBy","valueCode":"RR"}]},{"code":"SDD","display":"Susceptible-dose dependent","definition":"A category that includes isolates with antimicrobial agent minimum inhibitory concentrations (MICs) that approach usually attainable blood and tissue levels and for which response rates may be lower than for susceptible isolates.\r\n\r\nReference: CLSI document M44-A2 2009 \"Method for antifungal disk diffusion susceptibility testing of yeasts; approved guideline - second edition\" - page 2.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23558"},{"code":"subsumedBy","valueCode":"S"}]},{"code":"SYN-S","display":"Synergy - susceptible","definition":"A category for isolates where the bacteria (e.g. enterococci) are susceptible in vitro to a combination therapy (e.g., high-level aminoglycoside and cell wall active agent). This is predictive that this combination therapy will be effective.\r\n\r\n*Usage Note:* Since the use of penicillin or ampicillin alone often results in treatment failure of serious enterococcal or other bacterial infections, combination therapy is usually indicated to enhance bactericidal activity. The synergy between a cell wall active agent (such as penicillin, ampicillin, or vancomycin) and an aminoglycoside (such as gentamicin, kanamycin or streptomycin) is best predicted by screening for high-level bacterial resistance to the aminoglycoside.\r\n\r\n*Open Issue:* The print name of the code is very general and the description is very specific to a pair of classes of agents, which may lead to confusion of these concepts in the future should other synergies be found.","property":[{"code":"status","valueCode":"active"},{"code":"internalId","valueCode":"23620"},{"code":"subsumedBy","valueCode":"S"}]}]}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2618 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639569 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'; The provided code 'http://snomed.info/sct#10828004 ('Positive (qualifier value)')' was not found in the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "10828004","display" : "Positive (qualifier value)"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://snomed.info/sct#10828004 ('Positive (qualifier value)')' was not found in the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n78 78: tx-op\r\n78 0: 0ms http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3: Analysing\r\n78 0: 0ms http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3: Parameters: disp-lang=en-US, default-to-latest\r\n78 0: 0ms http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3: CodeSystem found: \"http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation|3.0.0\"\r\n78 0: 0ms http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3: Validate \"[http://snomed.info/sct#10828004 (\"Positive (qualifier value)\")]\"\r\n78 0: 0ms http://hl7.org/fhir/ValueSet/observation-interpretation|6.0.0-ballot3: Check \"http://snomed.info/sct#10828004\"\r\n"}]}
#810
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689","display":"FGFR2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639571 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3689"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3689 (\"FGFR2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3689\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#811
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2548 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639573 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3689"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:3689 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:3689\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#812
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:3689","display":"FGFR2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1506 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639575 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:3689"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:3689 (\"FGFR2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:3689\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#813
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G","display":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:929 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639577 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"NC_000010.11:g.121498525T>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#814
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000010.11:g.121498525T>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1418 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639579 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000010.11:g.121498525T>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000010.11:g.121498525T>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NC_000010.11:g.121498525T>G\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n78 62: 62ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NC_000010.11:g.121498525T>G\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#815
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"genetic-therapeutic-implications-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs","version":"4.0.0-ballot","name":"GeneticTherapeuticImplicationsVS","title":"Genetic Therapeutic Implications","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for terms that describe a predicted ramification based on the presence of associated molecular finding(s).","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.\nThis value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement.","compose":{"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]},{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2114 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639582 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Check \"http://snomed.info/sct#399223003\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: CodeSystem found: http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201 for http://snomed.info/sct\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/genetic-therapeutic-implications-vs|4.0.0-ballot: Code \"399223003\" found in http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\r\n"}]}
#816
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"399223003","display":"Patient eligible for clinical trial"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1177 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639584 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "399223003"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Patient eligible for clinical trial (finding)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "399223003","display" : "Patient eligible for clinical trial"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#399223003 (\"Patient eligible for clinical trial\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#399223003\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#817
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"254837009","display":"Breast Cancer"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1110 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:29 GMT last-modified:Thu, 16 Oct 2025 23:43:29 GMT pragma:no-cache server:nginx x-request-id:238-2639587 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "254837009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant tumor of breast"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "254837009","display" : "Breast Cancer"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#254837009 (\"Breast Cancer\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#254837009\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#818
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://clinicaltrials.gov","code":"NCT01234567","display":"NCT01234567"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1532 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:30 GMT last-modified:Thu, 16 Oct 2025 23:43:30 GMT pragma:no-cache server:nginx x-request-id:238-2639589 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://clinicaltrials.gov"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://clinicaltrials.gov"},{"name" : "code","valueCode" : "NCT01234567"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://clinicaltrials.gov' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://clinicaltrials.gov#NCT01234567 (\"NCT01234567\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://clinicaltrials.gov#NCT01234567\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://clinicaltrials.gov\"\r\n"}]}
#819
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000017.11"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639591 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000017.11"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000017.11\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#820
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1109 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639593 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30100-4\"\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}
#821
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:938 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639595 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30100-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30100-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#822
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4048-6","name":"LOINCAnswersLL4048-6","title":"LOINC Answer Codes for LL4048-6","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1108 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639597 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Check \"http://loinc.org#LA26418-6\"\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL4048-6: Filter \"LIST = LL4048-6\": Code \"LA26418-6\" found in http://loinc.org|2.81\r\n"}]}
#823
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117","display":"SMN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1508 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639599 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11117"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11117 (\"SMN1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11117\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#824
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639601 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11117"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11117 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11117\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#825
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11117","display":"SMN1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639603 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11117"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11117 (\"SMN1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11117\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#826
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639605 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#827
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:937 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639607 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26418-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "PCR"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26418-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#828
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26418-6","display":"PCR"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4050-2","name":"LOINCAnswersLL4050-2","title":"LOINC Answer Codes for LL4050-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2256 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:32 GMT last-modified:Thu, 16 Oct 2025 23:43:32 GMT pragma:no-cache server:nginx x-request-id:238-2639609 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'; The provided code 'http://loinc.org#LA26418-6 ('PCR')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26418-6 ('PCR')' was not found in the value set 'http://loinc.org/vs/LL4050-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL4050-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Analysing\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Validate \"[http://loinc.org#LA26418-6 (\"PCR\")]\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Check \"http://loinc.org#LA26418-6\"\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n16 0: 0ms http://loinc.org/vs/LL4050-2: Filter \"LIST = LL4050-2\": Code \"LA26418-6\" not found in http://loinc.org|2.81\r\n"}]}
#829
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"5262007","display":"Spinal muscular atrophy (disorder)"}],"text":"Spinal muscular atrophy (SMA)"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1190 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639611 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "5262007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Spinal muscular atrophy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "5262007","display" : "Spinal muscular atrophy (disorder)"}],"text" : "Spinal muscular atrophy (SMA)"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#5262007 (\"Spinal muscular atrophy (disorder)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#5262007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#830
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NC_000001.10:g.86852621A>G","display":"NC_000001.10:g.86852621A>G"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:924 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639613 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NC_000001.10:g.86852621A>G"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NC_000001.10:g.86852621A>G"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G (\"NC_000001.10:g.86852621A>G\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NC_000001.10:g.86852621A>G\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#831
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69547-8","display":"Genomic Ref allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:989 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639615 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69547-8","display" : "Genomic Ref allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"Genomic Ref allele [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#832
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"69551-0","display":"Genomic Alt allele [ID]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:989 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639617 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "69551-0","display" : "Genomic Alt allele [ID]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"Genomic Alt allele [ID]\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#833
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL5323-2","name":"LOINCAnswersLL5323-2","title":"LOINC Answer Codes for LL5323-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1183 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639619 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Check \"http://loinc.org#LA30100-4\"\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL5323-2: Filter \"LIST = LL5323-2\": Code \"LA30100-4\" found in http://loinc.org|2.81\r\n"}]}
#834
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA30100-4","display":"0-based interval counting"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:996 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639621 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA30100-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "0-based interval counting"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA30100-4 (\"0-based interval counting\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA30100-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#835
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Variant exact start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:964 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639623 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Variant exact start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#836
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8"}],"text":"Population allele frequency"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:975 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639625 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8"}],"text" : "Population allele frequency"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#837
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction","code":"HIGH","display":"High"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1868 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639628 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction"},{"name" : "code","valueCode" : "HIGH"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH (\"High\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction#HIGH\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/pcingola.github.io/SnpEff/se_inputoutput/#impact-prediction\"\r\n"}]}
#838
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395525.1","display":"NM_001395525.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1600 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639630 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001395525.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001395525.1 (\"NM_001395525.1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001395525.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#839
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575","display":"splice_donor_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:33 GMT last-modified:Thu, 16 Oct 2025 23:43:33 GMT pragma:no-cache server:nginx x-request-id:238-2639632 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001575"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001575 (\"splice_donor_variant\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001575\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#840
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1570 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639634 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#841
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2749 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639636 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001575"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001575 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001575\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#842
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639638 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#843
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001575","display":"splice_donor_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639640 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001575"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001575 (\"splice_donor_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001575\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#844
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1567 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639642 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#845
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C","display":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:897 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639644 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"NM_001366781.1:c.90T>C\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#846
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001366781.1:c.90T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1385 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639646 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001366781.1:c.90T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001366781.1:c.90T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001366781.1:c.90T>C (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001366781.1:c.90T>C\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n63 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001366781.1:c.90T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#847
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001366781.1","display":"NM_001366781.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1600 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639648 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001366781.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001366781.1 (\"NM_001366781.1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001366781.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#848
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819","display":"synonymous_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1571 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639650 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001819"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001819 (\"synonymous_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001819\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#849
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2749 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639652 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001819"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001819 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001819\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#850
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001819","display":"synonymous_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1571 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:34 GMT last-modified:Thu, 16 Oct 2025 23:43:34 GMT pragma:no-cache server:nginx x-request-id:238-2639654 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001819"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001819 (\"synonymous_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001819\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#851
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C","display":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:914 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639656 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"NM_001395543.1:c.-171T>C\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://varnomen.hgvs.org|2.0\" (content = complete)\r\n"}]}
#852
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://varnomen.hgvs.org","code":"NM_001395543.1:c.-171T>C"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://varnomen.hgvs.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1403 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639658 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://varnomen.hgvs.org"},{"name" : "code","valueCode" : "NM_001395543.1:c.-171T>C"},{"name" : "version","valueString" : "2.0"},{"name" : "display","valueString" : "NM_001395543.1:c.-171T>C"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: \"http://varnomen.hgvs.org|2.0\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Validate \"[http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Check \"http://varnomen.hgvs.org#NM_001395543.1:c.-171T>C\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: CodeSystem found: http://varnomen.hgvs.org|2.0 for http://varnomen.hgvs.org\r\n79 63: 63ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs--0|4.0.0-ballot: Code \"NM_001395543.1:c.-171T>C\" found in http://varnomen.hgvs.org|2.0\r\n"}]}
#853
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395543.1","display":"NM_001395543.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1607 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639660 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001395543.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001395543.1 (\"NM_001395543.1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001395543.1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#854
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623","display":"5_prime_UTR_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1572 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639662 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001623 (\"5_prime_UTR_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001623\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#855
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639664 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001623 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001623\"\r\n15 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#856
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001623","display":"5_prime_UTR_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1572 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639666 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001623"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001623 (\"5_prime_UTR_variant\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001623\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#857
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_001395544.1","display":"NM_001395544.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1600 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639668 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_001395544.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_001395544.1 (\"NM_001395544.1\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_001395544.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#858
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1574 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639670 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#859
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2757 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639672 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot' because the code system http://www.sequenceontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.sequenceontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs--0|4.0.0-ballot: CodeSystem not found: http://www.sequenceontology.org\r\n"}]}
#860
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001627","display":"intron_variant"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1574 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:35 GMT last-modified:Thu, 16 Oct 2025 23:43:35 GMT pragma:no-cache server:nginx x-request-id:238-2639674 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001627"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001627 (\"intron_variant\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001627\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#861
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://purl.obolibrary.org/obo/mondo.owl","code":"MONDO:0009061","display":"cystic fibrosis"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1640 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639676 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://purl.obolibrary.org/obo/mondo.owl"},{"name" : "code","valueCode" : "MONDO:0009061"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://purl.obolibrary.org/obo/mondo.owl' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://purl.obolibrary.org/obo/mondo.owl#MONDO:0009061 (\"cystic fibrosis\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://purl.obolibrary.org/obo/mondo.owl#MONDO:0009061\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://purl.obolibrary.org/obo/mondo.owl\"\r\n"}]}
#862
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1619 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639678 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"Autosomal recessive inheritance\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://human-phenotype-ontology.org\"\r\n"}]}
#863
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2837 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639680 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot' because the code system http://human-phenotype-ontology.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot' because the code system http://human-phenotype-ontology.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Analysing\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: CodeSystem not found: \"http://human-phenotype-ontology.org\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n16 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs--0|4.0.0-ballot: CodeSystem not found: http://human-phenotype-ontology.org\r\n"}]}
#864
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://human-phenotype-ontology.org","code":"HP:0000007","display":"Autosomal recessive inheritance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1619 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639682 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://human-phenotype-ontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://human-phenotype-ontology.org"},{"name" : "code","valueCode" : "HP:0000007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://human-phenotype-ontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://human-phenotype-ontology.org#HP:0000007 (\"Autosomal recessive inheritance\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://human-phenotype-ontology.org#HP:0000007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://human-phenotype-ontology.org\"\r\n"}]}
#865
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118","display":"SMN2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639684 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11118"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11118 (\"SMN2\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11118\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#866
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0","version":"4.0.0-ballot","status":"active","compose":{"include":[{"system":"http://www.genenames.org"}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2543 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639686 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11118"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated; Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNABLE_TO_CHECK_IF_THE_PROVIDED_CODES_ARE_IN_THE_VALUE_SET_CS"}],"severity" : "warning","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "vs-invalid"}],"text" : "Unable to check whether the code is in the value set 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot' because the code system http://www.genenames.org| was not found"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Analysing\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: \"http://www.genenames.org\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Validate \"[http://www.genenames.org#HGNC:11118 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: Check \"http://www.genenames.org#HGNC:11118\"\r\n0 0: 0ms http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs--0|4.0.0-ballot: CodeSystem not found: http://www.genenames.org\r\n"}]}
#867
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.genenames.org","code":"HGNC:11118","display":"SMN2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1515 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639688 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.genenames.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.genenames.org"},{"name" : "code","valueCode" : "HGNC:11118"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.genenames.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.genenames.org#HGNC:11118 (\"SMN2\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.genenames.org#HGNC:11118\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.genenames.org\"\r\n"}]}
#868
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"92821-8","display":"Allelic frequency in Population"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1013 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639690 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "92821-8","display" : "Allelic frequency in Population"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"Allelic frequency in Population\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#869
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26806-2","display":"GRCh38"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:946 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:36 GMT last-modified:Thu, 16 Oct 2025 23:43:36 GMT pragma:no-cache server:nginx x-request-id:238-2639692 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26806-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "GRCh38"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA26806-2 (\"GRCh38\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA26806-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#870
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001483","display":"SNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1556 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639694 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001483"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001483 (\"SNV\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001483\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#871
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002007","display":"MNV"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1563 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639696 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002007"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002007 (\"MNV\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002007\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#872
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:1000032","display":"delins"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1566 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639698 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:1000032"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:1000032 (\"delins\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:1000032\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#873
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001019","display":"copy_number_variation"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1574 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639700 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001019"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001019 (\"copy_number_variation\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001019\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#874
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"53037-8"}],"text":"Genetic variation clinical significance"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:994 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639702 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "53037-8"}],"text" : "Genetic variation clinical significance"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#875
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81259-4"}],"text":"Predicted phenotype"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:949 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639704 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81259-4"}],"text" : "Predicted phenotype"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#876
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405501007","display":"Malignant hyperthermia"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1132 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639707 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405501007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Malignant hyperthermia"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405501007","display" : "Malignant hyperthermia"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#405501007 (\"Malignant hyperthermia\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#405501007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#877
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic source class [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:994 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639710 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic source class [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"Genomic source class [Type]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#878
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000019.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639712 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000019.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000019.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000019.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#879
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81254-5"}],"text":"Genomic allele start-end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:965 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639714 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81254-5"}],"text" : "Genomic allele start-end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#880
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2D6_*1/*1","display":"CYP2D6 *1/*1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1522 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639716 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2D6_*1/*1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2D6_*1/*1 (\"CYP2D6 *1/*1\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2D6_*1/*1\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#881
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.pharmvar.org","code":"CYP2C19_*1/*2","display":"CYP2C19 *1/*2"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1519 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:37 GMT last-modified:Thu, 16 Oct 2025 23:43:37 GMT pragma:no-cache server:nginx x-request-id:238-2639718 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.pharmvar.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.pharmvar.org"},{"name" : "code","valueCode" : "CYP2C19_*1/*2"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.pharmvar.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.pharmvar.org#CYP2C19_*1/*2 (\"CYP2C19 *1/*2\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.pharmvar.org#CYP2C19_*1/*2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.pharmvar.org\"\r\n"}]}
#882
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://glstring.org","version":"1.0","code":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39","display":"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1905 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639720 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://glstring.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://glstring.org"},{"name" : "code","valueCode" : "hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39"},{"name" : "version","valueString" : "1.0"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM_VERSION_NONE"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://glstring.org' version '1.0' could not be found, so the code cannot be validated. No versions of this code system are known"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39 (\"hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://glstring.org|1.0#hla#3.33.0#HLA-A*02:69+HLA-A*23:30|HLA-A*02:302+HLA-A*23:26/HLA-A*23:39\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://glstring.org|1.0\"\r\n"}]}
#883
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000005.9"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639722 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000005.9"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000005.9 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000005.9\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#884
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:945 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639724 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#LA9633-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#885
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48019-4","display":"DNA Change Type"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:965 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639726 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48019-4","display" : "DNA Change Type"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"DNA Change Type\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#886
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000007.13"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639728 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000007.13"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000007.13 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000007.13\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#887
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"48002-0","display":"Genomic Source Class"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:980 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639730 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "48002-0","display" : "Genomic Source Class"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"Genomic Source Class\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#888
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"81302-2"}],"text":"Variant inner start and end"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:982 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639732 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "81302-2"}],"text" : "Variant inner start and end"}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#889
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA9633-4","display":"present"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1971-2","name":"LOINCAnswersLL1971-2","title":"LOINC Answer Codes for LL1971-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1124 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639734 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA9633-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Present"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "present"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Validate \"[http://loinc.org#LA9633-4 (\"present\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Check \"http://loinc.org#LA9633-4\"\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1971-2: Filter \"LIST = LL1971-2\": Code \"LA9633-4\" found in http://loinc.org|2.81\r\n"}]}
#890
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000007.14"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639736 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000007.14"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000007.14 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000007.14\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#891
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"82155-3","display":"Genomic Structural Variant copy Number"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1027 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639738 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "82155-3","display" : "Genomic Structural Variant copy Number"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"Genomic Structural Variant copy Number\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#892
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://www.nlm.nih.gov/research/umls/rxnorm","code":"480167","display":"Lapatinib"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1074 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639740 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://www.nlm.nih.gov/research/umls/rxnorm"},{"name" : "code","valueCode" : "480167"},{"name" : "version","valueString" : "??"},{"name" : "display","valueString" : "lapatinib"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://www.nlm.nih.gov/research/umls/rxnorm","code" : "480167","display" : "Lapatinib"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.nlm.nih.gov/research/umls/rxnorm#480167 (\"Lapatinib\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.nlm.nih.gov/research/umls/rxnorm#480167\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://www.nlm.nih.gov/research/umls/rxnorm|??\" (content = complete)\r\n"}]}
#893
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"443968007","display":"Sequencing of entire coding region of gene (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1228 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:38 GMT last-modified:Thu, 16 Oct 2025 23:43:38 GMT pragma:no-cache server:nginx x-request-id:238-2639742 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "443968007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Sequencing of entire coding region of gene (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "443968007","display" : "Sequencing of entire coding region of gene (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#443968007 (\"Sequencing of entire coding region of gene (procedure)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#443968007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#894
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://unitsofmeasure.org","code":"a"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:802 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639744 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://unitsofmeasure.org"},{"name" : "code","valueCode" : "a"},{"name" : "version","valueString" : "2.2"},{"name" : "display","valueString" : "a"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://unitsofmeasure.org#a (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://unitsofmeasure.org#a\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://unitsofmeasure.org|2.2\" (content = complete)\r\n"}]}
#895
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"94231-8","display":"G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1108 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639746 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94231-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "94231-8","display" : "G6PD gene full mutation analysis in Blood or Tissue by Sequencing"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94231-8 (\"G6PD gene full mutation analysis in Blood or Tissue by Sequencing\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94231-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#896
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://example.org/hgsc.bcm.edu/lab-test-codes/","code":"emerge-seq-ngs-pnl"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1689 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639748 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://example.org/hgsc.bcm.edu/lab-test-codes/"},{"name" : "code","valueCode" : "emerge-seq-ngs-pnl"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://example.org/hgsc.bcm.edu/lab-test-codes/' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://example.org/hgsc.bcm.edu/lab-test-codes/#emerge-seq-ngs-pnl\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://example.org/hgsc.bcm.edu/lab-test-codes/\"\r\n"}]}
#897
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"405825005","display":"Molecular genetic test (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1168 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639750 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "405825005"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Molecular genetic test (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "405825005","display" : "Molecular genetic test (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#405825005 (\"Molecular genetic test (procedure)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#405825005\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#898
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"108252007","display":"Laboratory procedure"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1126 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639752 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "108252007"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Laboratory procedure"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "108252007","display" : "Laboratory procedure"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#108252007 (\"Laboratory procedure\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#108252007\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#899
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"13298-5","display":"HLA-A [Type]"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:949 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639754 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "13298-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "HLA-A [Type]"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "13298-5","display" : "HLA-A [Type]"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#13298-5 (\"HLA-A [Type]\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#13298-5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#900
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"258564008","display":"Buccal smear sample"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1123 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639756 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "258564008"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal smear sample"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "258564008","display" : "Buccal smear sample"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#258564008 (\"Buccal smear sample\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#258564008\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#901
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"122610009","display":"Specimen from lung obtained by biopsy (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1192 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639758 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "122610009"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Specimen from lung obtained by biopsy"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "122610009","display" : "Specimen from lung obtained by biopsy (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#122610009 (\"Specimen from lung obtained by biopsy (specimen)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#122610009\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#902
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"129314006","display":"Biopsy - action"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1111 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639760 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "129314006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Biopsy - action"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "129314006","display" : "Biopsy - action"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#129314006 (\"Biopsy - action\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#129314006\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#903
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"119297000","display":"Blood specimen (specimen)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1130 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639762 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "119297000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Blood specimen"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "119297000","display" : "Blood specimen (specimen)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#119297000 (\"Blood specimen (specimen)\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#119297000\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#904
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"418622002","display":"Taking oral swab (procedure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1150 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639764 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "418622002"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Taking oral swab (procedure)"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "418622002","display" : "Taking oral swab (procedure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 15: 15ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#418622002 (\"Taking oral swab (procedure)\")]\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#418622002\"\r\n15 0: 15ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#905
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"261063000","display":"Buccal space"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1102 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639766 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "261063000"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Buccal space"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "261063000","display" : "Buccal space"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#261063000 (\"Buccal space\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#261063000\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#906
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://snomed.info/sct","code":"3341006","display":"Right lung structure (body structure)"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1135 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:39 GMT last-modified:Thu, 16 Oct 2025 23:43:39 GMT pragma:no-cache server:nginx x-request-id:238-2639768 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://snomed.info/sct"},{"name" : "code","valueCode" : "3341006"},{"name" : "version","valueString" : "http://snomed.info/sct/900000000000207008/version/20250201"},{"name" : "display","valueString" : "Right lung"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://snomed.info/sct","code" : "3341006","display" : "Right lung structure (body structure)"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://snomed.info/sct#3341006 (\"Right lung structure (body structure)\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://snomed.info/sct#3341006\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://snomed.info/sct|http://snomed.info/sct/900000000000207008/version/20250201\" (content = complete)\r\n"}]}
#907
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL4049-4","name":"LOINCAnswersLL4049-4","title":"LOINC Answer Codes for LL4049-4","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4049-4"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1124 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:40 GMT last-modified:Thu, 16 Oct 2025 23:43:40 GMT pragma:no-cache server:nginx x-request-id:238-2639770 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "LA26421-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Consider alternative medication"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0"}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Validate \"[http://loinc.org#LA26421-0 (\"\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Check \"http://loinc.org#LA26421-0\"\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL4049-4: Filter \"LIST = LL4049-4\": Code \"LA26421-0\" found in http://loinc.org|2.81\r\n"}]}
#908
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26421-0","display":"Consider alternative medication"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2368 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:40 GMT last-modified:Thu, 16 Oct 2025 23:43:40 GMT pragma:no-cache server:nginx x-request-id:238-2639772 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26421-0 ('Consider alternative medication')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26421-0","display" : "Consider alternative medication"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26421-0 ('Consider alternative medication')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26421-0 (\"Consider alternative medication\")]\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26421-0\"\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n15 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26421-0\" not found in http://loinc.org|2.81\r\n"}]}
#909
POST https://tx.fhir.org/r5/ValueSet/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"codeableConcept","valueCodeableConcept":{"coding":[{"system":"http://loinc.org","code":"LA26422-8","display":"Decrease dose"}]}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"valueSet","resource":{"resourceType":"ValueSet","url":"http://loinc.org/vs/LL1037-2","name":"LOINCAnswersLL1037-2","title":"LOINC Answer Codes for LL1037-2","status":"active","copyright":"This content LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use","compose":{"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1037-2"}]}]}}},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2287 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:40 GMT last-modified:Thu, 16 Oct 2025 23:43:40 GMT pragma:no-cache server:nginx x-request-id:238-2639774 {"resourceType" : "Parameters","parameter" : [{"name" : "version","valueString" : "2.81"},{"name" : "result","valueBoolean" : false},{"name" : "message","valueString" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'; The provided code 'http://loinc.org#LA26422-8 ('Decrease dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},{"name" : "codeableConcept","valueCodeableConcept" : {"coding" : [{"system" : "http://loinc.org","code" : "LA26422-8","display" : "Decrease dose"}]}},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "None_of_the_provided_codes_are_in_the_value_set_one"}],"severity" : "information","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "this-code-not-in-vs"}],"text" : "The provided code 'http://loinc.org#LA26422-8 ('Decrease dose')' was not found in the value set 'http://loinc.org/vs/LL1037-2'"},"location" : ["CodeableConcept.coding[0].code"],"expression" : ["CodeableConcept.coding[0].code"]},{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "TX_GENERAL_CC_ERROR_MESSAGE"}],"severity" : "error","code" : "code-invalid","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-in-vs"}],"text" : "No valid coding was found for the value set 'http://loinc.org/vs/LL1037-2'"}}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Analysing\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: \"http://loinc.org|2.81\"\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Validate \"[http://loinc.org#LA26422-8 (\"Decrease dose\")]\"\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Check \"http://loinc.org#LA26422-8\"\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: CodeSystem found: http://loinc.org|2.81 for http://loinc.org\r\n0 0: 0ms http://loinc.org/vs/LL1037-2: Filter \"LIST = LL1037-2\": Code \"LA26422-8\" not found in http://loinc.org|2.81\r\n"}]}
#910
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639776 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#911
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639778 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#912
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639780 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#913
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639782 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#914
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639784 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#915
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639786 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#916
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639788 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#917
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639790 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#918
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639792 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#919
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639794 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#920
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639796 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#921
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:54 GMT last-modified:Thu, 16 Oct 2025 23:43:54 GMT pragma:no-cache server:nginx x-request-id:238-2639798 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#922
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639800 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#923
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639802 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#924
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639804 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#925
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639806 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#926
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639808 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#927
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639810 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#928
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639812 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#929
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639814 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#930
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639816 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#931
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639818 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#932
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639820 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#933
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639822 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#934
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:55 GMT last-modified:Thu, 16 Oct 2025 23:43:55 GMT pragma:no-cache server:nginx x-request-id:238-2639824 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#935
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639826 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#936
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639828 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#937
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639830 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#938
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639832 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#939
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639834 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#940
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639836 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#941
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639838 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#942
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639840 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#943
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639842 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#944
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639844 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#945
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639846 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#946
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639848 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#947
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:56 GMT last-modified:Thu, 16 Oct 2025 23:43:56 GMT pragma:no-cache server:nginx x-request-id:238-2639850 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#948
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639852 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#949
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639854 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#950
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639856 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#951
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639858 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#952
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1583 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639860 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#953
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639862 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#954
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639864 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#955
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639866 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#956
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639868 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#957
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639870 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#958
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639872 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#959
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639874 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#960
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:57 GMT last-modified:Thu, 16 Oct 2025 23:43:57 GMT pragma:no-cache server:nginx x-request-id:238-2639876 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#961
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639878 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#962
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639880 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#963
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639882 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#964
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639884 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#965
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639886 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#966
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639888 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#967
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639890 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#968
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639892 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#969
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639894 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#970
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639896 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#971
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639898 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#972
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639900 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#973
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:58 GMT last-modified:Thu, 16 Oct 2025 23:43:58 GMT pragma:no-cache server:nginx x-request-id:238-2639902 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#974
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639904 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#975
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639906 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#976
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639908 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#977
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639910 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#978
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639912 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#979
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639914 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#980
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639916 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#981
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639918 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#982
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639920 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#983
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639922 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#984
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639924 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#985
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:43:59 GMT last-modified:Thu, 16 Oct 2025 23:43:59 GMT pragma:no-cache server:nginx x-request-id:238-2639926 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#986
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs368949613"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1619 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639928 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs368949613"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs368949613\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#987
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639930 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#988
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639932 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#989
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_014049.4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639934 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_014049.4"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_014049.4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#990
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_017064.1"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639936 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_017064.1"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_017064.1\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#991
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639938 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#992
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NM_000106.5"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1577 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639940 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NM_000106.5"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NM_000106.5\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#993
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://hl7.org/fhir/CodeSystem/medicationknowledge-status","code":"active"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:977 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:00 GMT last-modified:Thu, 16 Oct 2025 23:44:00 GMT pragma:no-cache server:nginx x-request-id:238-2639943 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://hl7.org/fhir/CodeSystem/medicationknowledge-status"},{"name" : "code","valueCode" : "active"},{"name" : "version","valueString" : "5.0.0"},{"name" : "display","valueString" : "Active"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status#active\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://hl7.org/fhir/CodeSystem/medicationknowledge-status|5.0.0 (from hl7.fhir.r5.core#5.0.0)\" (content = complete)\r\n"}]}
#994
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs12345"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1607 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:01 GMT last-modified:Thu, 16 Oct 2025 23:44:01 GMT pragma:no-cache server:nginx x-request-id:238-2639945 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs12345"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs12345\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#995
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NG_007726.3"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1584 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:01 GMT last-modified:Thu, 16 Oct 2025 23:44:01 GMT pragma:no-cache server:nginx x-request-id:238-2639947 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NG_007726.3"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NG_007726.3\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#996
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/projects/SNP","code":"rs233455"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1617 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:01 GMT last-modified:Thu, 16 Oct 2025 23:44:01 GMT pragma:no-cache server:nginx x-request-id:238-2639949 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/projects/SNP"},{"name" : "code","valueCode" : "rs233455"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/projects/SNP' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/projects/SNP#rs233455\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/projects/SNP\"\r\n"}]}
#997
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1587 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:01 GMT last-modified:Thu, 16 Oct 2025 23:44:01 GMT pragma:no-cache server:nginx x-request-id:238-2639951 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#998
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.ncbi.nlm.nih.gov/refseq","code":"NC_000010.10"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1580 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:01 GMT last-modified:Thu, 16 Oct 2025 23:44:01 GMT pragma:no-cache server:nginx x-request-id:238-2639953 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.ncbi.nlm.nih.gov/refseq"},{"name" : "code","valueCode" : "NC_000010.10"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.ncbi.nlm.nih.gov/refseq' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.ncbi.nlm.nih.gov/refseq#NC_000010.10\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.ncbi.nlm.nih.gov/refseq\"\r\n"}]}
#999
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org"}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:473 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:07 GMT server:nginx x-request-id:238-2639958 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>The value set '' expansion has too many codes to display (>10000)</p></div>"},"issue" : [{"severity" : "error","code" : "too-costly","details" : {"text" : "The value set '' expansion has too many codes to display (>10000)"},"diagnostics" : "0 0 : start\r\n0 0: not in cache\r\n0 0: tx-op\r\n0 0: 0ms start working\r\n0 0: 0ms compose #1\r\n"}]}
#1000
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"observation-codes","meta":{"lastUpdated":"2025-04-01T12:16:37.966+11:00","profile":["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"oo"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"draft"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":1}],"url":"http://hl7.org/fhir/ValueSet/observation-codes","identifier":[{"system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.396"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.3.383"},{"use":"old","system":"urn:ietf:rfc:3986","value":"urn:oid:2.16.840.1.113883.4.642.2.216"}],"version":"6.0.0-ballot3","name":"LOINCCodes","title":"LOINC Codes","status":"draft","experimental":false,"publisher":"FHIR Project team","contact":[{"telecom":[{"system":"url","value":"http://hl7.org/fhir"}]}],"description":"This value set includes all LOINC codes","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"copyright":"This content from LOINC® is copyright © 1995 Regenstrief Institute, Inc. and the LOINC Committee, and available at no cost under the license at http://loinc.org/terms-of-use.","compose":{"include":[{"system":"http://loinc.org"}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:116824 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:08 GMT last-modified:Thu, 16 Oct 2025 23:44:08 GMT pragma:no-cache server:nginx x-request-id:238-2639960 {"resourceType" : "ValueSet","meta" : {"lastUpdated" : "2025-04-01T12:16:37.966+11:00","profile" : ["http://hl7.org/fhir/StructureDefinition/shareablevalueset"]},"url" : "http://hl7.org/fhir/ValueSet/observation-codes","identifier" : [{"system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.3.396"},{"use" : "old","system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.3.383"},{"use" : "old","system" : "urn:ietf:rfc:3986","value" : "urn:oid:2.16.840.1.113883.4.642.2.216"}],"version" : "6.0.0-ballot3","name" : "LOINCCodes","title" : "LOINC Codes","status" : "draft","experimental" : false,"jurisdiction" : [{"coding" : [{"system" : "http://unstats.un.org/unsd/methods/m49/m49.htm","code" : "001","display" : "World"}]}],"expansion" : {"identifier" : "urn:uuid:294f9e17-6688-4eb1-a67f-b339f6c88474","timestamp" : "2025-10-16T23:44:07.625Z","offset" : 0,"parameter" : [{"name" : "limitedExpansion","valueBoolean" : true},{"name" : "displayLanguage","valueCode" : "en"},{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "100000-9","display" : "Health informatics pioneer and the father of LOINC"},{"system" : "http://loinc.org","code" : "100001-7","display" : "Health informatics pioneer and cofounder of LOINC"},{"system" : "http://loinc.org","code" : "100002-5","display" : "Specimen care is maintained"},{"system" : "http://loinc.org","code" : "100003-3","display" : "Team communication is maintained throughout care"},{"system" : "http://loinc.org","code" : "100004-1","display" : "Demonstrates knowledge of the expected psychosocial responses to the procedure"},{"system" : "http://loinc.org","code" : "100005-8","display" : "Demonstrates knowledge of nutritional management related to the procedure"},{"system" : "http://loinc.org","code" : "100006-6","display" : "Demonstrates knowledge of medication management"},{"system" : "http://loinc.org","code" : "100007-4","display" : "Demonstrates knowledge of pain management"},{"system" : "http://loinc.org","code" : "10000-8","display" : "R wave duration in lead AVR"},{"system" : "http://loinc.org","code" : "100008-2","display" : "Demonstrates knowledge of wound management"},{"system" : "http://loinc.org","code" : "100009-0","display" : "Demonstrates knowledge of the procedure and expected results"},{"system" : "http://loinc.org","code" : "100010-8","display" : "No injury related to procedure equipment, medical supplies, or instrumentation"},{"system" : "http://loinc.org","code" : "100011-6","display" : "No injury related to an electrical source"},{"system" : "http://loinc.org","code" : "100012-4","display" : "Participates in decisions affecting the patient's plan of care"},{"system" : "http://loinc.org","code" : "100013-2","display" : "Participates in the discharge process"},{"system" : "http://loinc.org","code" : "100014-0","display" : "Psychosocial health is maintained at or improved from baseline"},{"system" : "http://loinc.org","code" : "100015-7","display" : "No injury related to positioning due to care or procedure"},{"system" : "http://loinc.org","code" : "10001-6","display" : "R wave duration in lead I"},{"system" : "http://loinc.org","code" : "100016-5","display" : "No injury related to a laser source"},{"system" : "http://loinc.org","code" : "100017-3","display" : "Perioperative nursing data set outcomes panel [PNDS]"},{"system" : "http://loinc.org","code" : "100018-1","display" : "Hospice care Note"},{"system" : "http://loinc.org","code" : "100019-9","display" : "ALK gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100020-7","display" : "GNA11 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100021-5","display" : "GNAQ gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100022-3","display" : "IDH1 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100023-1","display" : "IDH2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "10002-4","display" : "R wave duration in lead II"},{"system" : "http://loinc.org","code" : "100024-9","display" : "SETBP1 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100025-6","display" : "SRSF2 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100026-4","display" : "MET gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100027-2","display" : "SMAD4 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100028-0","display" : "FBXW7 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal"},{"system" : "http://loinc.org","code" : "100029-8","display" : "Cancer related multigene analysis in Plasma cell-free DNA by Molecular genetics method"},{"system" : "http://loinc.org","code" : "100030-6","display" : "Axis I: Temporal aspects score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "100031-4","display" : "Axis II: Spatial aspects score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "10003-2","display" : "R wave duration in lead III"},{"system" : "http://loinc.org","code" : "100032-2","display" : "Axis III: Drug taking behavior score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "100033-0","display" : "Axis IV: Utilization of the health care system score [Mainz Pain Staging System]"},{"system" : "http://loinc.org","code" : "100034-8","display" : "Provider of automated external defibrillator use"},{"system" : "http://loinc.org","code" : "100035-5","display" : "Exam finding location of Chest"},{"system" : "http://loinc.org","code" : "100036-3","display" : "Exam finding location of Lung"},{"system" : "http://loinc.org","code" : "100037-1","display" : "Patient contact 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#1001
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#1002
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#1003
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"condition-inheritance-mode-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/condition-inheritance-mode-vs","version":"4.0.0-ballot","name":"ConditionInheritanceModeVS","title":"Condition Inheritance Patterns","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"Value Set for specific transmission patterns of a condition in a pedigree","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://human-phenotype-ontology.org","concept":[{"code":"HP:0000006","display":"Autosomal dominant inheritance"},{"code":"HP:0000007","display":"Autosomal recessive inheritance"},{"code":"HP:0001417","display":"X-linked inheritance"},{"code":"HP:0001419","display":"X-linked recessive inheritance"},{"code":"HP:0001423","display":"X-linked dominant inheritance"},{"code":"HP:0001426","display":"Multifactorial inheritance"},{"code":"HP:0001427","display":"Mitochondrial inheritance"},{"code":"HP:0001442","display":"Typified by somatic mosaicism"},{"code":"HP:0001450","display":"Y-linked inheritance"},{"code":"HP:0001470","display":"Sex-limited expression"},{"code":"HP:0003743","display":"Genetic anticipation"},{"code":"HP:0003745","display":"Sporadic"},{"code":"HP:0010983","display":"Oligogenic inheritance"},{"code":"HP:0012274","display":"Autosomal dominant inheritance with paternal imprinting"},{"code":"HP:0012275","display":"Autosomal dominant inheritance with maternal imprinting"},{"code":"HP:0025352","display":"Typically de novo"},{"code":"HP:0032113","display":"Semidominant inheritance"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:379 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:08 GMT server:nginx x-request-id:238-2639968 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://human-phenotype-ontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://human-phenotype-ontology.org"}}]}
#1004
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.genenames.org"}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:357 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:10 GMT server:nginx x-request-id:238-2639971 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.genenames.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.genenames.org"}}]}
#1005
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"hgnc-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs","version":"4.0.0-ballot","name":"HGNCVS","title":"HUGO Gene Nomenclature Committee Gene Names (HGNC)","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"This value set includes all HGNC Codes, which includes multiple code systems. In this guide, Gene IDs from HGNC are used as CodeableConcepts, which must be sent with the HGNC gene ID including the prefix 'HGNC:' as the code and the HGNC 'gene symbol' as display. CAUTION: HGNC also indexes gene groups by numeric ID (without a prefix), and older systems may send HGNC gene IDs without the prefix, so care must be taken to confirm alignment. We have separately included the genegroup code system to draw attention to this ambiguity and potential error.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.genenames.org"},{"system":"http://www.genenames.org/genegroup"}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:357 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:10 GMT server:nginx x-request-id:238-2639975 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.genenames.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.genenames.org"}}]}
#1006
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:819 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:10 GMT last-modified:Thu, 16 Oct 2025 23:44:10 GMT pragma:no-cache server:nginx x-request-id:238-2639977 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1007
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1040-6"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:872 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:10 GMT last-modified:Thu, 16 Oct 2025 23:44:10 GMT pragma:no-cache server:nginx x-request-id:238-2639979 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:0dacb50b-deab-4517-8b8e-6c4876456b18","timestamp" : "2025-10-16T23:44:10.498Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA14032-9","display" : "NCBI Build 34"},{"system" : "http://loinc.org","code" : "LA14029-5","display" : "GRCh37"},{"system" : "http://loinc.org","code" : "LA14030-3","display" : "NCBI Build 36.1"},{"system" : "http://loinc.org","code" : "LA14031-1","display" : "NCBI Build 35"},{"system" : "http://loinc.org","code" : "LA26806-2","display" : "GRCh38"}]}}
#1008
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL2938-0"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2413 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:10 GMT last-modified:Thu, 16 Oct 2025 23:44:10 GMT pragma:no-cache server:nginx x-request-id:238-2639981 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:c3ad1135-ef3d-41b7-8dde-40e53a5276ee","timestamp" : "2025-10-16T23:44:10.587Z","total" : 24,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA21254-0","display" : "Chromosome 1"},{"system" : "http://loinc.org","code" : "LA21255-7","display" : "Chromosome 2"},{"system" : "http://loinc.org","code" : "LA21256-5","display" : "Chromosome 3"},{"system" : "http://loinc.org","code" : "LA21257-3","display" : "Chromosome 4"},{"system" : "http://loinc.org","code" : "LA21258-1","display" : "Chromosome 5"},{"system" : "http://loinc.org","code" : "LA21259-9","display" : "Chromosome 6"},{"system" : "http://loinc.org","code" : "LA21260-7","display" : "Chromosome 7"},{"system" : "http://loinc.org","code" : "LA21261-5","display" : "Chromosome 8"},{"system" : "http://loinc.org","code" : "LA21262-3","display" : "Chromosome 9"},{"system" : "http://loinc.org","code" : "LA21263-1","display" : "Chromosome 10"},{"system" : "http://loinc.org","code" : "LA21264-9","display" : "Chromosome 11"},{"system" : "http://loinc.org","code" : "LA21265-6","display" : "Chromosome 12"},{"system" : "http://loinc.org","code" : "LA21266-4","display" : "Chromosome 13"},{"system" : "http://loinc.org","code" : "LA21267-2","display" : "Chromosome 14"},{"system" : "http://loinc.org","code" : "LA21268-0","display" : "Chromosome 15"},{"system" : "http://loinc.org","code" : "LA21269-8","display" : "Chromosome 16"},{"system" : "http://loinc.org","code" : "LA21270-6","display" : "Chromosome 17"},{"system" : "http://loinc.org","code" : "LA21271-4","display" : "Chromosome 18"},{"system" : "http://loinc.org","code" : "LA21272-2","display" : "Chromosome 19"},{"system" : "http://loinc.org","code" : "LA21273-0","display" : "Chromosome 20"},{"system" : "http://loinc.org","code" : "LA21274-8","display" : "Chromosome 21"},{"system" : "http://loinc.org","code" : "LA21275-5","display" : "Chromosome 22"},{"system" : "http://loinc.org","code" : "LA21276-3","display" : "Chromosome X"},{"system" : "http://loinc.org","code" : "LA21277-1","display" : "Chromosome Y"}]}}
#1009
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:11 GMT last-modified:Thu, 16 Oct 2025 23:44:11 GMT pragma:no-cache server:nginx x-request-id:238-2639983 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1010
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4050-2"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:821 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:15 GMT last-modified:Thu, 16 Oct 2025 23:44:15 GMT pragma:no-cache server:nginx x-request-id:238-2639985 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:cb9ea3d0-ef13-4ae0-a030-eac2c539781a","timestamp" : "2025-10-16T23:44:15.925Z","total" : 4,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26426-9","display" : "Directly measured"},{"system" : "http://loinc.org","code" : "LA26427-7","display" : "Family DNA"},{"system" : "http://loinc.org","code" : "LA26428-5","display" : "Family history"},{"system" : "http://loinc.org","code" : "LA26429-3","display" : "Inferred from population data"}]}}
#1011
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","concept":[{"code":"85337-4","display":"Estrogen receptor Ag Immune stain Ql (Breast cancer specimen)"},{"code":"72382-5","display":"HER2 IA Qn (Tiss)"},{"code":"77637-7","display":"HLA-A and B and C (class I) IgG panel IA [Identifier]"},{"code":"40557-1","display":"Progesterone receptor Ag Immune stain Ql (Tiss)"},{"code":"85147-7","display":"PD-L1 by clone 22C3 Immune stain Doc (Tiss)"},{"code":"59025-7","display":"Neutrophil Ab FC Qn (S)"},{"code":"59003-4","display":"Lactoferrin Ab IA Qn (S)"},{"code":"10495-0","display":"Insulin Ag Immune stain Ql (Tiss)"},{"code":"16550-6","display":"Carbohydrates Nom (U)"},{"code":"2569-2","display":"Lipids (S) [Mass/Vol]"},{"code":"4551-8","display":"Hemoglobin A2 (Bld) [Mass fraction]"},{"code":"19195-7","display":"Prostate specific Ag Qn"},{"code":"64083-9","display":"MGMT gene methylation score Molgen (Tiss) [Ratio]"},{"code":"62862-8","display":"Microsatellite instability Immune stain Ql (Tiss)"},{"code":"81704-9","display":"Microsatellite instability marker D17S250 Ql (Cancer specimen)"},{"code":"94077-5","display":"Tumor mutation burden Ql (Tumor) [Interp]"}]}]}}}]}
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#1012
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#1013
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#1014
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://varnomen.hgvs.org"}]}}}]}
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#1015
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001537"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:371 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:18 GMT server:nginx x-request-id:238-2640000 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.sequenceontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.sequenceontology.org"}}]}
#1016
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#1017
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}}]}
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#1018
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"functional-effect-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/functional-effect-vs","version":"4.0.0-ballot","name":"FunctionalEffectVS","title":"Functional Effect Value Set","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"The effect of a variant on downstream biological products or pathways.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0001536"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:371 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:19 GMT server:nginx x-request-id:238-2640009 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.sequenceontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.sequenceontology.org"}}]}
#1019
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","concept":[{"code":"LA10315-2","display":"Ultrarapid metabolizer"},{"code":"LA25391-6","display":"Normal metabolizer"},{"code":"LA25390-8","display":"Rapid metabolizer"},{"code":"LA10317-8","display":"Intermediate metabolizer"},{"code":"LA9657-3","display":"Poor metabolizer"},{"code":"LA19542-2","display":"Low Risk"},{"code":"LA19541-4","display":"High Risk"},{"code":"LA6676-6","display":"Resistant"},{"code":"LA6677-4","display":"Responsive"},{"code":"LA9660-7","display":"Presumed resistant"},{"code":"LA9661-5","display":"Presumed responsive"},{"code":"LA6682-4","display":"Unknown Significance"},{"code":"LA6675-8","display":"Benign"},{"code":"LA6674-1","display":"Presumed Benign"},{"code":"LA9662-3","display":"Presumed non-responsive"},{"code":"LA25392-4","display":"Increased function"},{"code":"LA25393-2","display":"Normal function"},{"code":"LA25395-7","display":"Decreased function"},{"code":"LA25394-0","display":"Poor function"}]}]}}}]}
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#1020
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://snomed.info/sct","concept":[{"code":"444734003","display":"Does not meet eligibility criteria for clinical trial (finding)"},{"code":"399223003","display":"Patient eligible for clinical trial (finding)"}]}]}}}]}
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#1021
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL1971-2"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:782 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:22 GMT last-modified:Thu, 16 Oct 2025 23:44:22 GMT pragma:no-cache server:nginx x-request-id:238-2640017 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:0319f081-45c4-4b36-92a1-4d2f7f8c0b81","timestamp" : "2025-10-16T23:44:22.241Z","total" : 4,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA9633-4","display" : "Present"},{"system" : "http://loinc.org","code" : "LA9634-2","display" : "Absent"},{"system" : "http://loinc.org","code" : "LA18198-4","display" : "No call"},{"system" : "http://loinc.org","code" : "LA11884-6","display" : "Indeterminate"}]}}
#1022
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
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#1023
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5323-2"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:760 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:22 GMT last-modified:Thu, 16 Oct 2025 23:44:22 GMT pragma:no-cache server:nginx x-request-id:238-2640021 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:ef09b262-e713-4d48-b433-4a3b07ec63fe","timestamp" : "2025-10-16T23:44:22.411Z","total" : 3,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA30100-4","display" : "0-based interval counting"},{"system" : "http://loinc.org","code" : "LA30101-2","display" : "0-based character counting"},{"system" : "http://loinc.org","code" : "LA30102-0","display" : "1-based character counting"}]}}
#1024
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}
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#1025
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"_limit","valueInteger":10000},{"name":"_incomplete","valueBoolean":true},{"name":"displayLanguage","valueCode":"en"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"valueSet","resource":{"resourceType":"ValueSet","id":"dna-change-type-vs","text":{"status":"generated","div":"<div>!-- Narrative removed --></div>"},"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cg"},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm","valueInteger":2,"_valueInteger":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}},{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status","valueCode":"trial-use","_valueCode":{"extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom","valueCanonical":"http://hl7.org/fhir/uv/genomics-reporting/ImplementationGuide/genomics-reporting"}]}}],"url":"http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs","version":"4.0.0-ballot","name":"DNAChangeTypeVS","title":"DNA Change Type","status":"active","experimental":false,"date":"2025-10-16T23:38:27+00:00","publisher":"HL7 International / Clinical Genomics","contact":[{"name":"HL7 International / Clinical Genomics","telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/clingenomics"},{"system":"email","value":"cg@lists.HL7.org"}]}],"description":"DNA Change Type of a variant.","jurisdiction":[{"coding":[{"system":"http://unstats.un.org/unsd/methods/m49/m49.htm","code":"001","display":"World"}]}],"compose":{"include":[{"system":"http://www.sequenceontology.org","filter":[{"property":"concept","op":"is-a","value":"SO:0002072"}]}]}}}]}
422 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location connection:keep-alive content-length:371 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:22 GMT server:nginx x-request-id:238-2640027 {"resourceType" : "OperationOutcome","text" : {"status" : "generated","div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>Unable to provide support for code system http://www.sequenceontology.org</p></div>"},"issue" : [{"severity" : "error","code" : "not-supported","details" : {"text" : "Unable to provide support for code system http://www.sequenceontology.org"}}]}
#1026
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL378-1"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1111 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:22 GMT last-modified:Thu, 16 Oct 2025 23:44:22 GMT pragma:no-cache server:nginx x-request-id:238-2640029 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:920fddb7-4c6d-43cb-b018-8e4495c33808","timestamp" : "2025-10-16T23:44:22.674Z","total" : 8,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA6683-2","display" : "Germline"},{"system" : "http://loinc.org","code" : "LA6684-0","display" : "Somatic"},{"system" : "http://loinc.org","code" : "LA10429-1","display" : "Fetal"},{"system" : "http://loinc.org","code" : "LA18194-3","display" : "Likely germline"},{"system" : "http://loinc.org","code" : "LA18195-0","display" : "Likely somatic"},{"system" : "http://loinc.org","code" : "LA18196-8","display" : "Likely fetal"},{"system" : "http://loinc.org","code" : "LA18197-6","display" : "Unknown genomic origin"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"}]}}
#1027
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL381-5"}]}]}}}]}
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#1028
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL5489-1"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:856 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:22 GMT last-modified:Thu, 16 Oct 2025 23:44:22 GMT pragma:no-cache server:nginx x-request-id:238-2640033 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:e4b50fa1-d55c-4a75-aa52-58d50151e238","timestamp" : "2025-10-16T23:44:22.839Z","total" : 5,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26320-4","display" : "Maternal"},{"system" : "http://loinc.org","code" : "LA26321-2","display" : "Paternal"},{"system" : "http://loinc.org","code" : "LA26807-0","display" : "De novo"},{"system" : "http://loinc.org","code" : "LA4489-6","display" : "Unknown"},{"system" : "http://loinc.org","code" : "LA30680-5","display" : "Parental"}]}}
#1029
POST https://tx.fhir.org/r5/ValueSet/$expand HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"defaultDisplayLanguage","valueCode":"en-US"},{"name":"includeDefinition","valueBoolean":false},{"name":"excludeNested","valueBoolean":false},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"count","valueInteger":1000},{"name":"offset","valueInteger":0},{"name":"valueSet","resource":{"resourceType":"ValueSet","status":"active","compose":{"inactive":true,"include":[{"system":"http://loinc.org","filter":[{"property":"LIST","op":"=","value":"LL4048-6"}]}]}}}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:2420 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:22 GMT last-modified:Thu, 16 Oct 2025 23:44:22 GMT pragma:no-cache server:nginx x-request-id:238-2640035 {"resourceType" : "ValueSet","status" : "active","expansion" : {"identifier" : "urn:uuid:1b81fdb5-d945-4b7a-b234-3d315a87e569","timestamp" : "2025-10-16T23:44:22.940Z","total" : 23,"offset" : 0,"parameter" : [{"name" : "excludeNested","valueBoolean" : false},{"name" : "offset","valueInteger" : 0},{"name" : "count","valueInteger" : 1000},{"name" : "used-codesystem","valueUri" : "http://loinc.org|2.81"},{"name" : "version","valueUri" : "http://loinc.org|2.81"}],"contains" : [{"system" : "http://loinc.org","code" : "LA26398-0","display" : "Sequencing"},{"system" : "http://loinc.org","code" : "LA26399-8","display" : "Oligo aCGH"},{"system" : "http://loinc.org","code" : "LA26400-4","display" : "SNP array"},{"system" : "http://loinc.org","code" : "LA26401-2","display" : "BAC aCGH"},{"system" : "http://loinc.org","code" : "LA26402-0","display" : "Curated"},{"system" : "http://loinc.org","code" : "LA26403-8","display" : "Digital array"},{"system" : "http://loinc.org","code" : "LA26404-6","display" : "FISH"},{"system" : "http://loinc.org","code" : "LA26405-3","display" : "Gene expression array"},{"system" : "http://loinc.org","code" : "LA26406-1","display" : "Karyotyping"},{"system" : "http://loinc.org","code" : "LA26407-9","display" : "MAPH"},{"system" : "http://loinc.org","code" : "LA26408-7","display" : "MALDI-TOF"},{"system" : "http://loinc.org","code" : "LA26808-8","display" : "Merging"},{"system" : "http://loinc.org","code" : "LA26414-5","display" : "Multiple complete digestion"},{"system" : "http://loinc.org","code" : "LA26415-2","display" : "MLPA"},{"system" : "http://loinc.org","code" : "LA26417-8","display" : "Optical mapping"},{"system" : "http://loinc.org","code" : "LA26418-6","display" : "PCR"},{"system" : "http://loinc.org","code" : "LA26419-4","display" : "qPCR (real-time PCR)"},{"system" : "http://loinc.org","code" : "LA26420-2","display" : "ROMA"},{"system" : "http://loinc.org","code" : "LA26809-6","display" : "Denaturing high-pressure liquid chromatography (DHPLC)"},{"system" : "http://loinc.org","code" : "LA26810-4","display" : "DNA hybridization"},{"system" : "http://loinc.org","code" : "LA26811-2","display" : "Computational analysis"},{"system" : "http://loinc.org","code" : "LA26812-0","display" : "Single-stranded conformational polymorphism (SSCP)"},{"system" : "http://loinc.org","code" : "LA26813-8","display" : "Restriction fragment length polymorphism (RFLP)"}]}}
#1030
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0002072"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1564 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:24 GMT last-modified:Thu, 16 Oct 2025 23:44:24 GMT pragma:no-cache server:nginx x-request-id:238-2640037 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0002072"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0002072 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0002072\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#1031
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001536"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1557 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:24 GMT last-modified:Thu, 16 Oct 2025 23:44:24 GMT pragma:no-cache server:nginx x-request-id:238-2640039 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001536"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001536 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001536\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#1032
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://www.sequenceontology.org","code":"SO:0001537"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:1564 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:25 GMT last-modified:Thu, 16 Oct 2025 23:44:25 GMT pragma:no-cache server:nginx x-request-id:238-2640041 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : false},{"name" : "system","valueUri" : "http://www.sequenceontology.org"},{"name" : "x-caused-by-unknown-system","valueCanonical" : "http://www.sequenceontology.org"},{"name" : "code","valueCode" : "SO:0001537"},{"name" : "message","valueString" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},{"name" : "issues","resource" : {"resourceType" : "OperationOutcome","issue" : [{"extension" : [{"url" : "http://hl7.org/fhir/StructureDefinition/operationoutcome-message-id","valueString" : "UNKNOWN_CODESYSTEM"}],"severity" : "error","code" : "not-found","details" : {"coding" : [{"system" : "http://hl7.org/fhir/tools/CodeSystem/tx-issue-type","code" : "not-found"}],"text" : "A definition for CodeSystem 'http://www.sequenceontology.org' could not be found, so the code cannot be validated"},"location" : ["Coding.system"],"expression" : ["Coding.system"]}]}},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://www.sequenceontology.org#SO:0001537 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://www.sequenceontology.org#SO:0001537\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Didn't find CodeSystem \"http://www.sequenceontology.org\"\r\n"}]}
#1033
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"93044-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:806 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640044 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "93044-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Level of evidence"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#93044-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#93044-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1034
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53037-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:834 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640046 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53037-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variation clinical significance [Imp]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53037-8 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53037-8\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1035
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81259-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:802 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640048 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81259-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Associated phenotype"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81259-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81259-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1036
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48018-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:806 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640050 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48018-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Gene studied [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48018-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48018-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1037
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48001-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:815 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640052 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48001-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Cytogenetic (chromosome) location"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48001-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48001-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1038
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"62374-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:823 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640054 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "62374-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Human reference sequence assembly version"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#62374-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#62374-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1039
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48000-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:853 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640056 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48000-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Chromosome [Identifier] in Blood or Tissue by Molecular genetics method"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48000-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48000-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1040
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92821-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:813 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640058 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92821-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic frequency in Population"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92821-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92821-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1041
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84413-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:810 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640060 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84413-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genotype display name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84413-4 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84413-4\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1042
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"84414-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:803 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:32 GMT last-modified:Thu, 16 Oct 2025 23:44:32 GMT pragma:no-cache server:nginx x-request-id:238-2640062 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "84414-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Haplotype name"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#84414-2 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#84414-2\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1043
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48004-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:808 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640064 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48004-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change (c.HGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48004-6 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48004-6\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1044
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51958-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:823 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640066 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51958-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Transcript reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51958-7 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51958-7\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1045
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48005-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:807 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640068 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48005-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Amino acid change (pHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48005-3 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48005-3\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1046
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82120-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:795 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640070 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82120-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic phase"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82120-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82120-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1047
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"51963-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:806 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640072 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "51963-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Medication assessed [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#51963-7 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#51963-7\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1048
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69548-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:815 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640074 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69548-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genetic variant assessment"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69548-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69548-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1049
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81290-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:815 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640076 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81290-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic DNA change (gHGVS)"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81290-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81290-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1050
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81291-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:801 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640078 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81291-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Variant ISCN"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81291-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81291-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1051
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48013-7"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:820 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640080 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48013-7"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic reference sequence [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48013-7 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48013-7\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1052
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81254-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:813 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640082 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81254-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic allele start-end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81254-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81254-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1053
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81302-2"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:820 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640084 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81302-2"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant inner start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81302-2 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81302-2\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1054
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81301-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:820 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640086 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81301-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Structural variant outer start and end"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81301-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81301-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1055
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"92822-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:814 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:33 GMT last-modified:Thu, 16 Oct 2025 23:44:33 GMT pragma:no-cache server:nginx x-request-id:238-2640088 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "92822-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic coordinate system [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#92822-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#92822-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1056
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69547-8"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:805 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640090 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69547-8"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic ref allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69547-8 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69547-8\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1057
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"69551-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:812 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640092 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "69551-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic alt allele [ID]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#69551-0 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#69551-0\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1058
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48019-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:804 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640094 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48019-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "DNA change type"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n15 15: tx-op\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48019-4 (\"\")]\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48019-4\"\r\n15 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1059
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"48002-0"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:816 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640096 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "48002-0"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic source class [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#48002-0 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#48002-0\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1060
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81258-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:827 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640098 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81258-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Sample variant allelic frequency [NFr]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81258-6 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81258-6\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1061
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82121-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:807 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640100 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82121-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic read depth"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82121-5 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82121-5\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1062
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"53034-5"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:798 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640102 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "53034-5"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Allelic state"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#53034-5 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#53034-5\"\r\n16 16: 16ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1063
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"94186-4"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:823 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640104 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "94186-4"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Origin of germline genetic variant [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#94186-4 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#94186-4\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1064
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82309-6"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:812 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640106 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82309-6"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Basis for allelic phase [Type]"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n0 0: tx-op\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82309-6 (\"\")]\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82309-6\"\r\n0 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1065
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"81252-9"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:813 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640108 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "81252-9"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Discrete genetic variant"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#81252-9 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#81252-9\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}
#1066
POST https://tx.fhir.org/r5/CodeSystem/$validate-code? HTTP/1.0 Accept: application/fhir+json; fhirVersion=5.0 Content-Type: application/fhir+json; fhirVersion=5.0;charset=UTF-8 User-Agent: fhir/publisher {"resourceType":"Parameters","parameter":[{"name":"coding","valueCoding":{"system":"http://loinc.org","code":"82155-3"}},{"name":"displayLanguage","valueString":"en, en-US"},{"name":"default-to-latest-version","valueBoolean":true},{"name":"cache-id","valueId":"bb4758a3-f7b0-44a3-b771-b895f49291ce"},{"name":"x-system-cache-id","valueString":"dc8fd4bc-091a-424a-8a3b-6198ef146891"},{"name":"diagnostics","valueBoolean":true}]}
200 access-control-allow-methods:GET, POST, PUT, PATCH, DELETE access-control-allow-origin:* access-control-expose-headers:Content-Location, Location cache-control:public, max-age=600 connection:keep-alive content-length:827 content-type:application/fhir+json date:Thu, 16 Oct 2025 23:44:34 GMT last-modified:Thu, 16 Oct 2025 23:44:34 GMT pragma:no-cache server:nginx x-request-id:238-2640110 {"resourceType" : "Parameters","parameter" : [{"name" : "result","valueBoolean" : true},{"name" : "system","valueUri" : "http://loinc.org"},{"name" : "code","valueCode" : "82155-3"},{"name" : "version","valueString" : "2.81"},{"name" : "display","valueString" : "Genomic structural variant copy number"},{"name" : "diagnostics","valueString" : "0 0 : start\r\n16 16: tx-op\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Analysing\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Parameters: disp-lang=en, en-US, default-to-latest\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Validate \"[http://loinc.org#82155-3 (\"\")]\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Check \"http://loinc.org#82155-3\"\r\n16 0: 0ms http://hl7.org/fhir/ValueSet/@all: Using CodeSystem \"http://loinc.org|2.81\" (content = complete)\r\n"}]}