Order Catalog Implementation Guide, published by HL7 International - Orders and Observations Work Group. This is not an authorized publication; it is the continuous build for version current). This version is based on the current content of https://github.com/HL7/fhir-order-catalog/ and changes regularly. See the Directory of published versions
@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
a fhir:MedicationKnowledge;
fhir:nodeRole fhir:treeRoot;
fhir:Resource.id [ fhir:value "example-drug-clarithromycin-25mg-granule-suspension"]; #
fhir:Resource.meta [
fhir:Meta.profile [
fhir:value "http://hl7.org/fhir/uv/order-catalog/StructureDefinition/DrugKnowledge";
fhir:index 0;
fhir:link <http://hl7.org/fhir/uv/order-catalog/StructureDefinition/DrugKnowledge> ]
]; #
fhir:Resource.language [ fhir:value "en-US"]; #
fhir:DomainResource.text [
fhir:Narrative.status [ fhir:value "extensions" ];
fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en-US\" lang=\"en-US\"><p><b>Generated Narrative: MedicationKnowledge</b><a name=\"example-drug-clarithromycin-25mg-granule-suspension\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationKnowledge "example-drug-clarithromycin-25mg-granule-suspension" (Language "en-US") </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DrugKnowledge.html\">item in a catalog of drugs</a></p></div><p><b>Reference to a catalog</b>: <a href=\"Composition-example-medication-catalog-header.html\">Composition/example-medication-catalog-header</a></p><p><b>code</b>: Clarithromycin 25 mg/mL oral suspension <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#769316002)</span></p><p><b>intendedJurisdiction</b>: Healthyland <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>name</b>: CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension</p><p><b>productType</b>: Generic product <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><blockquote><p><b>indicationGuideline</b></p><h3>Indications</h3><table class=\"grid\"><tr><td>-</td><td><b>Reference</b></td></tr><tr><td>*</td><td><a href=\"ClinicalUseDefinition-example-bacterial-pharyngitis-indication.html\">ClinicalUseDefinition/example-bacterial-pharyngitis-indication</a></td></tr><tr><td>*</td><td><a href=\"ClinicalUseDefinition-example-acute-otitis-media-indication.html\">ClinicalUseDefinition/example-acute-otitis-media-indication</a></td></tr><tr><td>*</td><td><a href=\"ClinicalUseDefinition-example-bacterial-sinusitis-indication.html\">ClinicalUseDefinition/example-bacterial-sinusitis-indication</a></td></tr></table><blockquote><p><b>dosingGuideline</b></p><h3>PatientCharacteristics</h3><table class=\"grid\"><tr><td>-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td>*</td><td>Age <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#30525-0)</span></td><td>0.5-12 years</td></tr></table></blockquote></blockquote><blockquote><p><b>medicineClassification</b></p><p><b>type</b>: Anatomical Therapeutic Chemical (ATC) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>source</b>: <a href=\"https://www.whocc.no/atc/structure_and_principles/\">https://www.whocc.no/atc/structure_and_principles/</a></p><p><b>classification</b>: Clarithromycin <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-WC.html\">WHO ATC</a>#J01FA09)</span></p></blockquote><blockquote><p><b>medicineClassification</b></p><p><b>type</b>: SNOMED CT drug dispositions <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>source</b>: <a href=\"https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product\">https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product</a></p><p><b>classification</b>: Medicinal product acting as antibacterial agent <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#346325008)</span></p></blockquote><blockquote><p><b>packaging</b></p><h3>Costs</h3><table class=\"grid\"><tr><td>-</td><td><b>EffectiveDate</b></td><td><b>Type</b></td><td><b>Source</b></td><td><b>Cost[x]</b></td></tr><tr><td>*</td><td>2021-02-01 --> (ongoing)</td><td>public price <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>Healthyland Drug Administration</td><td><span title=\"Euro\">€5.18</span> (EUR)</td></tr><tr><td>*</td><td>2020-09-30 --> 2021-01-31</td><td>public price <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>Healthyland Drug Administration</td><td><span title=\"Euro\">€5.20</span> (EUR)</td></tr><tr><td>*</td><td>2010-03-01 --> (ongoing)</td><td>manufacturers' cost <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></td><td>Healthyland Drug Administration</td><td><span title=\"Euro\">€4.40</span> (EUR)</td></tr></table><p><b>packagedProduct</b>: <a href=\"PackagedProductDefinition-example-drug-package-clarithromycin.html\">PackagedProductDefinition/example-drug-package-clarithromycin</a> "Package for CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension in 100 ml HDPE bottle"</p></blockquote><p><b>clinicalUseIssue</b>: <a href=\"ClinicalUseDefinition-example-allergy-contraindication.html\">ClinicalUseDefinition/example-allergy-contraindication</a></p><blockquote><p><b>definitional</b></p><p><b>doseForm</b>: Granules for oral suspension <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#385029002; standardterms.edqm.eu#10113000)</span></p><p><b>intendedRoute</b>: Oral route <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#26643006)</span></p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td>-</td><td><b>Concept</b></td></tr><tr><td>*</td><td>Clarithromycin <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#387487009)</span></td></tr></table><p><b>type</b>: active ingredient - basis of strength <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-RoleClass.html\">RoleClass</a>#ACTIB)</span></p><p><b>strength</b>: 25 milligram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mg = 'mg')</span>/1 milliliter<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL = 'mL')</span></p></blockquote><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td>-</td><td><b>Concept</b></td></tr><tr><td>*</td><td>Sucrose <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#11320009)</span></td></tr></table><p><b>type</b>: inactive ingredient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.0.0/CodeSystem-v3-RoleClass.html\">RoleClass</a>#IACT)</span></p></blockquote></blockquote></div>"
]; #
fhir:DomainResource.extension [
fhir:index 0;
fhir:Extension.url [ fhir:value "http://hl7.org/fhir/uv/order-catalog/StructureDefinition/CatalogReference" ];
fhir:Extension.valueReference [
fhir:Reference.reference [ fhir:value "Composition/example-medication-catalog-header" ] ]
]; #
fhir:MedicationKnowledge.code [
fhir:CodeableConcept.coding [
fhir:index 0;
a sct:769316002;
fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
fhir:Coding.code [ fhir:value "769316002" ];
fhir:Coding.display [ fhir:value "Clarithromycin 25 mg/mL oral suspension" ] ]
]; #
fhir:MedicationKnowledge.intendedJurisdiction [
fhir:index 0;
fhir:CodeableConcept.text [ fhir:value "Healthyland" ]
]; #
fhir:MedicationKnowledge.name [
fhir:value "CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension";
fhir:index 0
]; #
fhir:MedicationKnowledge.productType [
fhir:index 0;
fhir:CodeableConcept.text [ fhir:value "Generic product" ]
]; #
fhir:MedicationKnowledge.indicationGuideline [
fhir:index 0;
fhir:MedicationKnowledge.indicationGuideline.indication [
fhir:index 0;
fhir:CodeableReference.reference [
fhir:Reference.reference [ fhir:value "ClinicalUseDefinition/example-bacterial-pharyngitis-indication" ] ] ], [
fhir:index 1;
fhir:CodeableReference.reference [
fhir:Reference.reference [ fhir:value "ClinicalUseDefinition/example-acute-otitis-media-indication" ] ] ], [
fhir:index 2;
fhir:CodeableReference.reference [
fhir:Reference.reference [ fhir:value "ClinicalUseDefinition/example-bacterial-sinusitis-indication" ] ] ];
fhir:MedicationKnowledge.indicationGuideline.dosingGuideline [
fhir:index 0;
fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic [
fhir:index 0;
fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.type [
fhir:CodeableConcept.coding [
fhir:index 0;
a loinc:30525-0;
fhir:Coding.system [ fhir:value "http://loinc.org" ];
fhir:Coding.code [ fhir:value "30525-0" ];
fhir:Coding.display [ fhir:value "Age" ] ] ];
fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueRange [
fhir:Range.low [
fhir:Quantity.value [ fhir:value "0.5"^^xsd:decimal ];
fhir:Quantity.unit [ fhir:value "years" ];
fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
fhir:Quantity.code [ fhir:value "a" ] ];
fhir:Range.high [
fhir:Quantity.value [ fhir:value "12"^^xsd:decimal ];
fhir:Quantity.unit [ fhir:value "years" ];
fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
fhir:Quantity.code [ fhir:value "a" ] ] ] ] ]
]; #
fhir:MedicationKnowledge.medicineClassification [
fhir:index 0;
fhir:MedicationKnowledge.medicineClassification.type [
fhir:CodeableConcept.text [ fhir:value "Anatomical Therapeutic Chemical (ATC)" ] ];
fhir:MedicationKnowledge.medicineClassification.sourceUri [ fhir:value "https://www.whocc.no/atc/structure_and_principles/" ];
fhir:MedicationKnowledge.medicineClassification.classification [
fhir:index 0;
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://www.whocc.no/atc" ];
fhir:Coding.code [ fhir:value "J01FA09" ];
fhir:Coding.display [ fhir:value "Clarithromycin" ] ] ]
], [
fhir:index 1;
fhir:MedicationKnowledge.medicineClassification.type [
fhir:CodeableConcept.text [ fhir:value "SNOMED CT drug dispositions" ] ];
fhir:MedicationKnowledge.medicineClassification.sourceUri [ fhir:value "https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product" ];
fhir:MedicationKnowledge.medicineClassification.classification [
fhir:index 0;
fhir:CodeableConcept.coding [
fhir:index 0;
a sct:346325008;
fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
fhir:Coding.code [ fhir:value "346325008" ];
fhir:Coding.display [ fhir:value "Medicinal product acting as antibacterial agent" ] ] ]
]; #
fhir:MedicationKnowledge.packaging [
fhir:index 0;
fhir:MedicationKnowledge.packaging.cost [
fhir:index 0;
fhir:MedicationKnowledge.cost.effectiveDate [
fhir:index 0;
fhir:Period.start [ fhir:value "2021-02-01"^^xsd:date ] ];
fhir:MedicationKnowledge.cost.type [
fhir:CodeableConcept.text [ fhir:value "public price" ] ];
fhir:MedicationKnowledge.cost.source [ fhir:value "Healthyland Drug Administration" ];
fhir:MedicationKnowledge.cost.costMoney [
fhir:Money.value [ fhir:value "5.18"^^xsd:decimal ];
fhir:Money.currency [ fhir:value "EUR" ] ] ], [
fhir:index 1;
fhir:MedicationKnowledge.cost.effectiveDate [
fhir:index 0;
fhir:Period.start [ fhir:value "2020-09-30"^^xsd:date ];
fhir:Period.end [ fhir:value "2021-01-31"^^xsd:date ] ];
fhir:MedicationKnowledge.cost.type [
fhir:CodeableConcept.text [ fhir:value "public price" ] ];
fhir:MedicationKnowledge.cost.source [ fhir:value "Healthyland Drug Administration" ];
fhir:MedicationKnowledge.cost.costMoney [
fhir:Money.value [ fhir:value "5.2"^^xsd:decimal ];
fhir:Money.currency [ fhir:value "EUR" ] ] ], [
fhir:index 2;
fhir:MedicationKnowledge.cost.effectiveDate [
fhir:index 0;
fhir:Period.start [ fhir:value "2010-03-01"^^xsd:date ] ];
fhir:MedicationKnowledge.cost.type [
fhir:CodeableConcept.text [ fhir:value "manufacturers' cost" ] ];
fhir:MedicationKnowledge.cost.source [ fhir:value "Healthyland Drug Administration" ];
fhir:MedicationKnowledge.cost.costMoney [
fhir:Money.value [ fhir:value "4.4"^^xsd:decimal ];
fhir:Money.currency [ fhir:value "EUR" ] ] ];
fhir:MedicationKnowledge.packaging.packagedProduct [
fhir:Reference.reference [ fhir:value "PackagedProductDefinition/example-drug-package-clarithromycin" ] ]
]; #
fhir:MedicationKnowledge.clinicalUseIssue [
fhir:index 0;
fhir:Reference.reference [ fhir:value "ClinicalUseDefinition/example-allergy-contraindication" ]
]; #
fhir:MedicationKnowledge.definitional [
fhir:MedicationKnowledge.definitional.doseForm [
fhir:CodeableConcept.coding [
fhir:index 0;
a sct:385029002;
fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
fhir:Coding.code [ fhir:value "385029002" ];
fhir:Coding.display [ fhir:value "Granules for oral suspension" ] ], [
fhir:index 1;
fhir:Coding.system [ fhir:value "http://standardterms.edqm.eu" ];
fhir:Coding.code [ fhir:value "10113000" ];
fhir:Coding.display [ fhir:value "Granules for oral suspension" ] ] ];
fhir:MedicationKnowledge.definitional.intendedRoute [
fhir:index 0;
fhir:CodeableConcept.coding [
fhir:index 0;
a sct:26643006;
fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
fhir:Coding.code [ fhir:value "26643006" ];
fhir:Coding.display [ fhir:value "Oral route" ] ] ];
fhir:MedicationKnowledge.definitional.ingredient [
fhir:index 0;
fhir:MedicationKnowledge.definitional.ingredient.item [
fhir:CodeableReference.concept [
fhir:CodeableConcept.coding [
fhir:index 0;
a sct:387487009;
fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
fhir:Coding.code [ fhir:value "387487009" ];
fhir:Coding.display [ fhir:value "Clarithromycin" ] ] ] ];
fhir:MedicationKnowledge.definitional.ingredient.type [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-RoleClass" ];
fhir:Coding.code [ fhir:value "ACTIB" ];
fhir:Coding.display [ fhir:value "active ingredient - basis of strength" ] ] ];
fhir:MedicationKnowledge.definitional.ingredient.strengthRatio [
fhir:Ratio.numerator [
fhir:Quantity.value [ fhir:value "25"^^xsd:decimal ];
fhir:Quantity.unit [ fhir:value "milligram" ];
fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
fhir:Quantity.code [ fhir:value "mg" ] ];
fhir:Ratio.denominator [
fhir:Quantity.value [ fhir:value "1"^^xsd:decimal ];
fhir:Quantity.unit [ fhir:value "milliliter" ];
fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
fhir:Quantity.code [ fhir:value "mL" ] ] ] ], [
fhir:index 1;
fhir:MedicationKnowledge.definitional.ingredient.item [
fhir:CodeableReference.concept [
fhir:CodeableConcept.coding [
fhir:index 0;
a sct:11320009;
fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
fhir:Coding.code [ fhir:value "11320009" ];
fhir:Coding.display [ fhir:value "Sucrose" ] ] ] ];
fhir:MedicationKnowledge.definitional.ingredient.type [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-RoleClass" ];
fhir:Coding.code [ fhir:value "IACT" ];
fhir:Coding.display [ fhir:value "inactive ingredient" ] ] ] ]
]. #
# - ontology header ------------------------------------------------------------
a owl:Ontology;
owl:imports fhir:fhir.ttl.
IG © 2021+ HL7 International - Orders and Observations Work Group. Package hl7.fhir.uv.order-catalog#current based on FHIR 5.0.0-ballot. Generated 2023-02-10
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