Profile Comparison between http://hl7.org/fhir/us/core/StructureDefinition/us-core-observation-lab vs http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-variant

Left:US Core Laboratory Result Observation Profile (http://hl7.org/fhir/us/core/StructureDefinition/us-core-observation-lab)
Right:Genomic Variant Profile (http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-variant)

Messages

ErrorStructureDefinition.urlValues for url differ: 'http://hl7.org/fhir/us/core/StructureDefinition/us-core-observation-lab' vs 'http://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-variant'
ErrorStructureDefinition.versionValues for version differ: '6.1.0' vs '3.0.0'
InformationStructureDefinition.nameValues for name differ: 'USCoreLaboratoryResultObservationProfile' vs 'GenomicVariant'
InformationStructureDefinition.titleValues for title differ: 'US Core Laboratory Result Observation Profile' vs 'Genomic Variant Profile'
InformationStructureDefinition.statusValues for status differ: 'active' vs 'draft'
InformationStructureDefinition.dateValues for date differ: '2022-11-19' vs '2023-10-25T20:34:07+00:00'
InformationStructureDefinition.publisherValues for publisher differ: 'HL7 International - Cross-Group Projects' vs 'HL7 International / Clinical Interoperability Council'
ErrorStructureDefinition.baseDefinitionValues for baseDefinition differ: 'http://hl7.org/fhir/us/core/StructureDefinition/us-core-observation-clinical-result' vs 'http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant'
InformationStructureDefinition.shortValues for short differ: 'Measurements and simple assertions' vs 'Variant'
InformationStructureDefinition.definitionValues for definition differ: '\-' vs 'Measurements and simple assertions made about a patient, device or other subject.'
InformationStructureDefinition.commentValues for comment differ: '\-' vs 'Used for simple observations such as device measurements, laboratory atomic results, vital signs, height, weight, smoking status, comments, etc. Other resources are used to provide context for observations such as laboratory reports, etc.'
InformationStructureDefinition.shortValues for short differ: 'Additional content defined by implementations' vs 'Extension'
InformationStructureDefinition.definitionValues for definition differ: 'May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.' vs 'An Extension'
InformationStructureDefinition.shortValues for short differ: '(USCDI) registered | preliminary | final | amended +' vs 'registered | preliminary | final | amended +'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Classification of type of observation' vs 'Classification of type of observation'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Laboratory Test Name' vs '69548-6'
InformationStructureDefinition.definitionValues for definition differ: 'The name of the clinical test or procedure performed on a patient. A LOINC **SHALL** be used if the concept is present in LOINC.' vs 'Describes what was observed. Sometimes this is called the observation 'name'.'
InformationStructureDefinition.commentValues for comment differ: 'The typical patterns for codes are: 1) a LOINC code either as a translation from a 'local' code or as a primary code, or 2) a local code only if no suitable LOINC exists, or 3) both the local and the LOINC translation. Systems SHALL be capable of sending the local code if one exists. When using LOINC , Use either the SHORTNAME or LONG_COMMON_NAME field for the display.' vs '*All* code-value and, if present, component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation.'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Who and/or what the observation is about' vs 'Who and/or what the observation is about'
InformationObservation.subjectElement minimum cardinalities differ: '1' vs '0'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Clinically relevant time/time-period for observation' vs 'Clinically relevant time/time-period for observation'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Result Value' vs 'Actual result'
InformationStructureDefinition.definitionValues for definition differ: 'The Laboratory result value. If a coded value, the valueCodeableConcept.code **SHOULD** be selected from [SNOMED CT](http://hl7.org/fhir/ValueSet/uslab-obs-codedresults) if the concept exists. If a numeric value, valueQuantity.code **SHALL** be selected from [UCUM](http://unitsofmeasure.org). A FHIR [UCUM Codes value set](http://hl7.org/fhir/STU3/valueset-ucum-units.html) that defines all UCUM codes is in the FHIR specification.' vs 'The information determined as a result of making the observation, if the information has a simple value.'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Why the result is missing' vs 'Why the result is missing'
InformationStructureDefinition.shortValues for short differ: 'Comments about the observation' vs 'Comments about the Observation that also contain a coded type'
InformationStructureDefinition.definitionValues for definition differ: 'Comments about the observation or the results.' vs 'A text note which also contains information about who made the statement and when.'
InformationStructureDefinition.commentValues for comment differ: 'May include general statements about the observation, or statements about significant, unexpected or unreliable results values, or information about its source when relevant to its interpretation.' vs 'May include general statements about the observation, or statements about significant, unexpected or unreliable results values, or information about its source when relevant to its interpretation. The CodedAnnotation data type, while not allowing for or intending to make the content computable, does allow the author to indicate the type of note. This does not replace the use of interpretation, value, or component values. One important note is that Annotation is a FHIR data type, this is **NOT** about annotations in the genomic context.'
InformationStructureDefinition.requirementsValues for requirements differ: 'Need to be able to provide free text additional information.' vs 'Need to be able to provide free text additional information. Notes SHALL NOT contain information which can be captured in a structured way.'
InformationStructureDefinition.shortValues for short differ: 'How it was done' vs 'Sequencing | SNP array | PCR | Computational analysis | ...'
WarningObservation.methodElements differ in definition for mustSupport: 'false' vs 'true'
InformationStructureDefinition.shortValues for short differ: '(USCDI) Specimen used for this observation' vs 'Specimen used for this observation'
InformationStructureDefinition.shortValues for short differ: 'Provides guide for interpretation' vs 'Not used in this profile'
InformationStructureDefinition.definitionValues for definition differ: 'Guidance on how to interpret the value by comparison to a normal or recommended range. Multiple reference ranges are interpreted as an 'OR'. In other words, to represent two distinct target populations, two `referenceRange` elements would be used.' vs 'Not used in this profile'
InformationStructureDefinition.shortValues for short differ: 'Related resource that belongs to the Observation group' vs 'Not used in this profile'
InformationStructureDefinition.definitionValues for definition differ: 'This observation is a group observation (e.g. a battery, a panel of tests, a set of vital sign measurements) that includes the target as a member of the group.' vs 'Not used in this profile'
WarningObservation.componentElements differ in definition for mustSupport: 'false' vs 'true'

Metadata

NameValueComments
.abstractfalse
    .baseDefinitionhttp://hl7.org/fhir/us/core/StructureDefinition/us-core-observation-clinical-resulthttp://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant
    • Values Differ
    .copyrightUsed by permission of HL7 International, all rights reserved Creative Commons License
    • Removed the item 'Used by permission of HL7 International, all rights reserved Creative Commons License'
    .date2022-11-192023-10-25T20:34:07+00:00
    • Values Differ
    .descriptionThe US Core Laboratory Result Observation Profile is based upon the US Core Observation Clinical Result Profile and, along with the US Core DiagnosticReport Profile for Laboratory Results Reporting, meets the U.S. Core Data for Interoperability (USCDI) Laboratory requirements. Laboratory results are grouped and summarized using the DiagnosticReport resource, which references Observation resources. Each Observation resource represents an individual laboratory test and result value, a “nested” panel (such as a microbial susceptibility panel) that references other observations, or rarely a laboratory test with component result values. The US Core Laboratory Result Observation Profile sets minimum expectations for the Observation resource to record, search, and fetch laboratory test results associated with a patient to promote interoperability and adoption through common implementation. It identifies which core elements, extensions, vocabularies, and value sets SHALL be present in the resource and constrains the way the elements are used when using this profile. It provides the floor for standards development for specific use cases.Details about a set of changes in the tested sample compared to a reference sequence. The term variant can be used to describe an alteration that may be benign, pathogenic, or of unknown significance. The term variant is increasingly being used in place of the term mutation. Variants can be computed relative to reference sequence assembly from which it was identified.
    • Values Differ
    .experimentalfalse
    • Removed the item 'false'
    .fhirVersion4.0.1
      .jurisdiction
        ..jurisdiction[0]urn:iso:std:iso:3166#US
          .kindresource
            .nameUSCoreLaboratoryResultObservationProfileGenomicVariant
            • Values Differ
            .publisherHL7 International - Cross-Group ProjectsHL7 International / Clinical Interoperability Council
            • Values Differ
            .purpose
              .statusactivedraft
              • Values Differ
              .titleUS Core Laboratory Result Observation ProfileGenomic Variant Profile
              • Values Differ
              .typeObservation
                .urlhttp://hl7.org/fhir/us/core/StructureDefinition/us-core-observation-labhttp://hl7.org/fhir/us/mcode/StructureDefinition/mcode-genomic-variant
                • Values Differ
                .version6.1.03.0.0
                • Values Differ

                Structure

                NameL FlagsL Card.L TypeL Description & ConstraintsR FlagsR Card.L TypeL Description & ConstraintsCommentsdoco
                .. Observation C0..*USCoreObservationClinicalResultProfileMeasurements and simple assertions
                C0..*VariantVariant
                  ... id Σ0..1idLogical id of this artifactΣ0..1idLogical id of this artifact
                    ... meta Σ0..1MetaMetadata about the resourceΣ0..1MetaMetadata about the resource
                      ... implicitRules ?!Σ0..1uriA set of rules under which this content was created?!Σ0..1uriA set of rules under which this content was created
                        ... language 0..1codeLanguage of the resource content
                        Binding: ?? (preferred): A human language.

                        Additional BindingsPurpose
                        ??Max Binding
                        0..1codeLanguage of the resource content
                        Binding: ?? (preferred): A human language.

                        Additional BindingsPurpose
                        ??Max Binding
                          ... text 0..1NarrativeText summary of the resource, for human interpretation0..1NarrativeText summary of the resource, for human interpretation
                            ... contained 0..*ResourceContained, inline Resources
                            0..*ResourceContained, inline Resources
                              ... extension 0..*ExtensionAdditional content defined by implementations
                              0..*ExtensionExtension
                              Slice: Unordered, Open by value:url
                                ... modifierExtension ?!0..*ExtensionExtensions that cannot be ignored
                                ?!0..*ExtensionExtensions that cannot be ignored
                                  ... identifier Σ0..*IdentifierBusiness Identifier for observation
                                  Σ0..*IdentifierBusiness Identifier for observation
                                    ... basedOn Σ0..*Reference(CarePlan | DeviceRequest | ImmunizationRecommendation | MedicationRequest | NutritionOrder | ServiceRequest)Fulfills plan, proposal or order
                                    Σ0..*Reference(CarePlan | DeviceRequest | ImmunizationRecommendation | MedicationRequest | NutritionOrder | ServiceRequest)Fulfills plan, proposal or order
                                      ... partOf Σ0..*Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Immunization | ImagingStudy)Part of referenced event
                                      Σ0..*Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Immunization | ImagingStudy)Part of referenced event
                                        ... status ?!SΣ1..1code(USCDI) registered | preliminary | final | amended +
                                        Binding: ?? (required): Codes providing the status of an observation.

                                        ?!SΣ1..1coderegistered | preliminary | final | amended +
                                        Binding: ?? (required): Codes providing the status of an observation.

                                          ... Slices for category S1..*CodeableConcept(USCDI) Classification of type of observation
                                          Slice: Unordered, Open by pattern:$this
                                          Binding: ?? (preferred): Codes for high level observation categories.


                                          S1..*CodeableConceptClassification of type of observation
                                          Slice: Unordered, Open by value:coding
                                          Binding: ?? (preferred): Codes for high level observation categories.


                                            ... code SΣ1..1CodeableConcept(USCDI) Laboratory Test Name
                                            Binding: ?? (extensible): Laboratory LOINC Codes

                                            SΣ1..1CodeableConcept69548-6
                                            Binding: ?? (example): Codes identifying names of simple observations.


                                            Required Pattern: {"coding":[{"system":"http://loinc.org","code":"69548-6"}]}
                                              ... subject SΣ1..1Reference(US Core Patient Profile)(USCDI) Who and/or what the observation is aboutSΣ0..1Reference(Cancer Patient Profile)Who and/or what the observation is about
                                              • Element minimum cardinalities differ: '1' vs '0'
                                              ... focus ΣTU0..*Reference(Resource)What the observation is about, when it is not about the subject of record
                                              ΣTU0..*Reference(Resource)What the observation is about, when it is not about the subject of record
                                                ... encounter Σ0..1Reference(Encounter)Healthcare event during which this observation is madeΣ0..1Reference(Encounter)Healthcare event during which this observation is made
                                                  ... effective[x] SΣC0..1dateTime S, Period, Timing, instant(USCDI) Clinically relevant time/time-period for observationSΣ0..1dateTime, Period, Timing, instantClinically relevant time/time-period for observation
                                                  Slice: Unordered, Open by type:$this
                                                    ... issued Σ0..1instantDate/Time this version was made availableΣ0..1instantDate/Time this version was made available
                                                      ... performer Σ0..*Reference(Practitioner | PractitionerRole | Organization | CareTeam | Patient | RelatedPerson)Who is responsible for the observation
                                                      Σ0..*Reference(Practitioner | PractitionerRole | Organization | CareTeam | Patient | RelatedPerson)Who is responsible for the observation
                                                        ... value[x] SΣC0..1Quantity S, CodeableConcept S, string S, boolean, integer, Range, Ratio, SampledData, time, dateTime, Period(USCDI) Result Value
                                                        us-core-4: SHOULD use Snomed CT for coded Results
                                                        SΣC0..1CodeableConceptActual result
                                                        Slice: Unordered, Closed by type:$this
                                                          ... dataAbsentReason SC0..1CodeableConcept(USCDI) Why the result is missing
                                                          Binding: ?? (extensible): Codes specifying why the result (Observation.value[x]) is missing.

                                                          SC0..1CodeableConceptWhy the result is missing
                                                          Binding: ?? (extensible): Codes specifying why the result (Observation.value[x]) is missing.

                                                            ... interpretation 0..*CodeableConceptHigh, low, normal, etc.
                                                            Binding: ?? (extensible): Codes identifying interpretations of observations.


                                                            0..*CodeableConceptHigh, low, normal, etc.
                                                            Binding: ?? (extensible): Codes identifying interpretations of observations.


                                                              ... note 0..*AnnotationComments about the observation
                                                              0..*??Comments about the Observation that also contain a coded type
                                                                ... bodySite 0..1CodeableConceptObserved body part
                                                                Binding: ?? (example): Codes describing anatomical locations. May include laterality.

                                                                0..1CodeableConceptObserved body part
                                                                Binding: ?? (example): Codes describing anatomical locations. May include laterality.

                                                                  ... method 0..1CodeableConceptHow it was done
                                                                  Binding: ?? (example): Methods for simple observations.

                                                                  S0..1CodeableConceptSequencing | SNP array | PCR | Computational analysis | ...
                                                                  Binding: ?? (extensible)
                                                                  • Elements differ in definition for mustSupport: 'false' vs 'true'
                                                                  ... specimen S0..1Reference(US Core Specimen Profile)(USCDI) Specimen used for this observationS0..1Reference(Human Specimen Profile)Specimen used for this observation
                                                                    ... device 0..1Reference(Device | DeviceMetric)(Measurement) Device0..1Reference(Device | DeviceMetric)(Measurement) Device
                                                                      ... referenceRange C0..*BackboneElementProvides guide for interpretation
                                                                      C0..*BackboneElementNot used in this profile
                                                                        .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                          .... extension 0..*ExtensionAdditional content defined by implementations
                                                                          0..*ExtensionAdditional content defined by implementations
                                                                            .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                            ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                              .... low C0..1??Low Range, if relevantC0..1??Low Range, if relevant
                                                                                .... high C0..1??High Range, if relevantC0..1??High Range, if relevant
                                                                                  .... type 0..1CodeableConceptReference range qualifier
                                                                                  Binding: ?? (preferred): Code for the meaning of a reference range.

                                                                                  0..1CodeableConceptReference range qualifier
                                                                                  Binding: ?? (preferred): Code for the meaning of a reference range.

                                                                                    .... appliesTo 0..*CodeableConceptReference range population
                                                                                    Binding: ?? (example): Codes identifying the population the reference range applies to.


                                                                                    0..*CodeableConceptReference range population
                                                                                    Binding: ?? (example): Codes identifying the population the reference range applies to.


                                                                                      .... age 0..1RangeApplicable age range, if relevant0..1RangeApplicable age range, if relevant
                                                                                        .... text 0..1stringText based reference range in an observation0..1stringText based reference range in an observation
                                                                                          ... hasMember Σ0..*Reference(Observation | QuestionnaireResponse | MolecularSequence)Related resource that belongs to the Observation group
                                                                                          Σ0..*Reference(Observation | QuestionnaireResponse | MolecularSequence)Not used in this profile
                                                                                            ... derivedFrom Σ0..*Reference(DocumentReference | ImagingStudy | Media | QuestionnaireResponse | Observation | MolecularSequence)Related measurements the observation is made from
                                                                                            Σ0..*Reference(DocumentReference | ImagingStudy | Media | QuestionnaireResponse | Observation | MolecularSequence)Related measurements the observation is made from
                                                                                              ... component Σ0..*BackboneElementComponent results
                                                                                              SΣ0..*BackboneElementComponent results
                                                                                              Slice: Unordered, Open by pattern:code
                                                                                              • Elements differ in definition for mustSupport: 'false' vs 'true'
                                                                                              .... id 0..1stringUnique id for inter-element referencing0..1stringUnique id for inter-element referencing
                                                                                                .... extension 0..*ExtensionAdditional content defined by implementations
                                                                                                0..*ExtensionAdditional content defined by implementations
                                                                                                  .... modifierExtension ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                  ?!Σ0..*ExtensionExtensions that cannot be ignored even if unrecognized
                                                                                                    .... code Σ1..1CodeableConceptType of component observation (code / type)
                                                                                                    Binding: ?? (example): Codes identifying names of simple observations.

                                                                                                    Σ1..1CodeableConceptType of component observation (code / type)
                                                                                                    Binding: ?? (example): Codes identifying names of simple observations.

                                                                                                      .... value[x] Σ0..1Quantity, CodeableConcept, string, boolean, integer, Range, Ratio, SampledData, time, dateTime, PeriodActual component resultΣ0..1Quantity, CodeableConcept, string, boolean, integer, Range, Ratio, SampledData, time, dateTime, PeriodActual component result
                                                                                                        .... dataAbsentReason C0..1CodeableConceptWhy the component result is missing
                                                                                                        Binding: ?? (extensible): Codes specifying why the result (Observation.value[x]) is missing.

                                                                                                        C0..1CodeableConceptWhy the component result is missing
                                                                                                        Binding: ?? (extensible): Codes specifying why the result (Observation.value[x]) is missing.

                                                                                                          .... interpretation 0..*CodeableConceptHigh, low, normal, etc.
                                                                                                          Binding: ?? (extensible): Codes identifying interpretations of observations.


                                                                                                          0..*CodeableConceptHigh, low, normal, etc.
                                                                                                          Binding: ?? (extensible): Codes identifying interpretations of observations.


                                                                                                            .... referenceRange 0..*See referenceRange (Observation)Provides guide for interpretation of component result
                                                                                                            0..*See referenceRange (Observation)Provides guide for interpretation of component result

                                                                                                              doco Documentation for this format