Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot2 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

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Extension: RelatesTo

Official URL: http://hl7.org/fhir/uv/ebm/StructureDefinition/relates-to				Version: 1.0.0-ballot2
Standards status: Draft			Maturity Level: 1	Computable Name: RelatesTo
Other Identifiers: OID:2.16.840.1.113883.4.642.40.44.42.84

Resource (FHIR or non-FHIR) associated with the Resource.

Context of Use

This extension may be used on the following element(s):

• Element ID: Evidence
• Element ID: EvidenceVariable
• Element ID: Citation
• Element ID: ArtifactAssessment
• Element ID: ArtifactAssessment.content
• Element ID: ArtifactAssessment.content.component
• Element ID: ResearchStudy
• Element ID: Group

Usage info

Usage:

• Use this Extension: ComparativeEvidence, CTISRecord, GroupR6, M11ResearchStudy... Show 5 more, NonComparativeEvidence, RecommendationJustification, StatisticModel, SystematicReview and VariableDefinition
• Examples for this Extension: ArtifactAssessment/179469, Citation/121719, Citation/139860, Citation/58... Show 309 more, ComparativeEvidence_Bypass_surgery_effects_on_Myocardial_infarction_or_stroke_in_Swedish_Obese_Subjects_SOS_study, ComparativeEvidence_Bypass_surgery_effects_on_Remission_of_diabetes_in_JAMA_2018_Norwegian_cohort_study, ComparativeEvidence_Bypass_surgery_effects_on_New_onset_depression_in_JAMA_2018_Norwegian_cohort_study, ComparativeEvidence_Bypass_surgery_effects_on_Treatment_with_opioids_in_JAMA_2018_Norwegian_cohort_study, ComparativeEvidence_Bypass_surgery_effects_on_Additional_GI_surgical_procedure_in_JAMA_2018_Norwegian_cohort_study, AllCauseMortalityControlGroup2022metaAnalysis, ComparatorOnlyEvidence_Additional_GI_surgical_procedure_without_bariatric_surgery_Control_Group_in_JAMA_2018_Norwegian_cohort_study, ComparatorOnlyEvidence_Treatment_with_opioids_without_bariatric_surgery_Control_Group_in_JAMA_2018_Norwegian_cohort_study, ComparatorOnlyEvidence_New_onset_depression_without_bariatric_surgery_Control_Group_in_JAMA_2018_Norwegian_cohort_study, ComparatorOnlyEvidence_Remission_of_diabetes_without_bariatric_surgery_Control_Group_in_JAMA_2018_Norwegian_cohort_study, ComparatorOnlyEvidence_Myocardial_infarction_or_stroke_without_bariatric_surgery_Control_Group_in_Swedish_Obese_Subjects_SOS_study, InterventionOnlyEvidence_Additional_GI_surgical_procedure_with_bariatric_surgery_Intervention_Group_in_JAMA_2018_Norwegian_cohort_study, InterventionOnlyEvidence_New_onset_depression_with_bariatric_surgery_Intervention_Group_in_JAMA_2018_Norwegian_cohort_study, InterventionOnlyEvidence_Remission_of_diabetes_with_bariatric_surgery_Intervention_Group_in_JAMA_2018_Norwegian_cohort_study, InterventionOnlyEvidence_Treatment_with_opioids_with_bariatric_surgery_Intervention_Group_in_JAMA_2018_Norwegian_cohort_study, BaselineMeasureEvidence_Age_in_2018_Norwegian_Cohort_Medical_Group, BaselineMeasureEvidence_Age_in_2018_Norwegian_Cohort_Surgical_Group, ComparativeBaselineMeasureEvidence_Age_in_2018_Norwegian_Cohort_Surgical_Group_vs_Medical_Group, ComparativeBaselineMeasureEvidence_BMI_in_2018_Norwegian_Cohort_Surgical_Group_vs_Medical_Group, BaselineMeasureEvidence_BMI_in_2018_Norwegian_Cohort_Surgical_Group, BaselineMeasureEvidence_BMI_in_2018_Norwegian_Cohort_Medical_Group, ParticipantFlowEvidence_2018_Norwegian_Cohort_Excluded_from_Analysis, ParticipantFlow_2018_Norwegian_Cohort_Included_in_Analysis, ParticipantFlow_2018_Norwegian_Cohort_Surgical_Group_Included_in_Analysis, ParticipantFlow_2018_Norwegian_Cohort_Medical_Group_Included_in_Analysis, NetEffectEstimate_Bariatric_Surgery_Example_for_GIN_2022, ComparativeParticipantFlowEvidence_Dropout_due_to_stopping_intervention_Lofexidine_vs_Placebo_in_opioid_detoxification_trial, ADAS_Cog11_EndpointAnalysisPlan_from_PHUSE_Lilly_Redacted_Protocol_EBMonFHIR_IG_Version, CIBIC_EndpointAnalysisPlan_from_PHUSE_Lilly_Redacted_Protocol_EBMonFHIR_IG_Version, Example_EndpointAnalysisPlan_from_PHUSE_Lilly_Redacted_Protocol_EBMonFHIR_IG_Version, All_cause_mortality_from_MAGICapp_313876, All_cause_mortality_Comparator_Evidence_from_MAGICapp_313876, Cardiovascular_mortality_from_MAGICapp_313877, Cardiovascular_mortality_Comparator_Evidence_from_MAGICapp_313877, Nonfatal_myocardial_infarction_from_MAGICapp_313878, Nonfatal_myocardial_infarction_Comparator_Evidence_from_MAGICapp_313878, Nonfatal_stroke_from_MAGICapp_313879, Nonfatal_stroke_Comparator_Evidence_from_MAGICapp_313879, End_stage_kidney_disease_from_MAGICapp_313880, End_stage_kidney_disease_Comparator_Evidence_from_MAGICapp_313880, Heart_failure_from_MAGICapp_313881, Heart_failure_Comparator_Evidence_from_MAGICapp_313881, Serious_hyperglycaemia_from_MAGICapp_313882, Serious_hyperglycaemia_Comparator_Evidence_from_MAGICapp_313882, Severe_gastrointestinal_events_from_MAGICapp_313883, Severe_gastrointestinal_events_Comparator_Evidence_from_MAGICapp_313883, Health_related_quality_of_life_from_MAGICapp_109569, Health_related_quality_of_life_Comparator_Evidence_from_MAGICapp_109569, Body_weight_from_MAGICapp_109570, Body_weight_Comparator_Evidence_from_MAGICapp_109570, All_cause_mortality_from_MAGICapp_313956, All_cause_mortality_Comparator_Evidence_from_MAGICapp_313956, Cardiovascular_mortality_from_MAGICapp_313957, Cardiovascular_mortality_Comparator_Evidence_from_MAGICapp_313957, Nonfatal_myocardial_infarction_from_MAGICapp_313958, Nonfatal_myocardial_infarction_Comparator_Evidence_from_MAGICapp_313958, Nonfatal_stroke_from_MAGICapp_313959, Nonfatal_stroke_Comparator_Evidence_from_MAGICapp_313959, End_stage_kidney_disease_from_MAGICapp_313960, End_stage_kidney_disease_Comparator_Evidence_from_MAGICapp_313960, Heart_failure_from_MAGICapp_313961, Heart_failure_Comparator_Evidence_from_MAGICapp_313961, Diabetic_ketoacidosis_from_MAGICapp_313962, Diabetic_ketoacidosis_Comparator_Evidence_from_MAGICapp_313962, Serious_hyperglycaemia_from_MAGICapp_313963, Serious_hyperglycaemia_Comparator_Evidence_from_MAGICapp_313963, Genital_infection_from_MAGICapp_313964, Genital_infection_Comparator_Evidence_from_MAGICapp_313964, Severe_gastrointestinal_events_from_MAGICapp_313965, Severe_gastrointestinal_events_Comparator_Evidence_from_MAGICapp_313965, Health_related_quality_of_life_from_MAGICapp_109587, Health_related_quality_of_life_Comparator_Evidence_from_MAGICapp_109587, Body_weight_from_MAGICapp_109588, Body_weight_Comparator_Evidence_from_MAGICapp_109588, All_cause_mortality_Intervention_Evidence_from_MAGICapp_313876, Cardiovascular_mortality_Intervention_Evidence_from_MAGICapp_313877 , Nonfatal_myocardial_infarction_Intervention_Evidence_from_MAGICapp_313878, Nonfatal_stroke_Intervention_Evidence_from_MAGICapp_313879, End_stage_kidney_disease_Intervention_Evidence_from_MAGICapp_313880, Heart_failure_Intervention_Evidence_from_MAGICapp_313881, Serious_hyperglycaemia_Intervention_Evidence_from_MAGICapp_313882, Severe_gastrointestinal_events_Intervention_Evidence_from_MAGICapp_313883, Health_related_quality_of_life_Intervention_Evidence_from_MAGICapp_109569, Body_weight_Intervention_Evidence_from_MAGICapp_109570, All_cause_mortality_Intervention_Evidence_from_MAGICapp_313956, Cardiovascular_mortality_Intervention_Evidence_from_MAGICapp_313957, Nonfatal_myocardial_infarction_Intervention_Evidence_from_MAGICapp_313958, Nonfatal_stroke_Intervention_Evidence_from_MAGICapp_313959, End_stage_kidney_disease_Intervention_Evidence_from_MAGICapp_313960, Heart_failure_Intervention_Evidence_from_MAGICapp_313961, Diabetic_ketoacidosis_Intervention_Evidence_from_MAGICapp_313962, Serious_hyperglycaemia_Intervention_Evidence_from_MAGICapp_313963, Genital_infection_Intervention_Evidence_from_MAGICapp_313964, Severe_gastrointestinal_events_Intervention_Evidence_from_MAGICapp_313965, Health_related_quality_of_life_Intervention_Evidence_from_MAGICapp_109587, Body_weight_Intervention_Evidence_from_MAGICapp_109588, Age_with_intervention, Age_with_comparator, Height_with_intervention, Height_with_comparator, History_of_Broken_Bones_with_intervention, History_of_Broken_Bones_with_comparator, Velocity_with_intervention, Velocity_with_comparator, Sex_with_intervention, Sex_with_comparator, Ethnic_Group_with_intervention, Ethnic_Group_with_comparator, History_of_Acrophobia_with_intervention, History_of_Acrophobia_with_comparator, History_of_Parachute_Use_with_intervention, History_of_Parachute_Use_with_comparator, Family_History_of_Parachute_Use_with_intervention, Family_History_of_Parachute_Use_with_comparator, Frequent_Flier_with_intervention, Frequent_Flier_with_comparator, International_vs_Domestic_Flight_with_intervention, International_vs_Domestic_Flight_with_comparator, Declined_randomization_in_PARACHUTE_Study, PARACHUTE_Trial_Participants_randomized_into_groups_with_intervention, PARACHUTE_Trial_Participants_randomized_into_groups_with_comparator, Altitude_with_intervention, Altitude_with_comparator, Weight_with_intervention, Weight_with_comparator, Aircraft_Type_with_intervention, Aircraft_Type_with_comparator, Velocity_for_non_participant_group, Altitude_for_screened_group, Velocity_for_enrolled_group, Altitude_for_enrolled_group, Altitude_comparing_intervention_vs_comparator, Velocity_comparing_intervention_vs_comparator, Excluded_from_PARACHUTE_Study, Deemed_unsuitable_by_investigator_in_PARACHUTE_Trial, PARACHUTE_Trial_Participants_randomized_into_groups_for_screened_group, Randomized_into_groups_for_PARACHUTE_Trial, PARACHUTE_Trial_Participants_that_completed_jump_and_5_minute_follow_up_with_intervention, PARACHUTE_Trial_Participants_that_completed_jump_and_5_minute_follow_up_with_comparator, PARACHUTE_Trial_Participants_with_no_contact_at_30_days_with_intervention, PARACHUTE_Trial_Participants_with_no_contact_at_30_days_with_comparator, PARACHUTE_Trial_Participants_that_completed_30_day_follow_up_with_intervention, PARACHUTE_Trial_Participants_that_completed_30_day_follow_up_with_comparator, Rate_of_Death_or_Major_Traumatic_Injury_on_Impact_with_intervention, Injury_Severity_Score_on_Impact_with_intervention, Death_or_Major_Traumatic_Injury_30_days_after_Impact_with_intervention, Injury_Severity_Score_30_days_after_Impact_with_intervention, Health_Survey_Score_Total_with_intervention, Health_Survey_Score_Physical_Health_Subscore_with_intervention, Health_Survey_Score_Mental_Health_Subscore_with_intervention, Injury_Severity_Score_on_Impact_comparing_intervention_vs_comparator, Rate_of_Death_or_Major_Traumatic_Injury_on_Impact_with_comparator, Injury_Severity_Score_on_Impact_with_comparator, Death_or_Major_Traumatic_Injury_30_days_after_Impact_with_comparator, Injury_Severity_Score_30_days_after_Impact_with_comparator, Health_Survey_Score_Total_with_comparator , Health_Survey_Score_Physical_Health_Subscore_with_comparator, Health_Survey_Score_Mental_Health_Subscore_with_comparator, Death_or_Major_Traumatic_Injury_on_Impact_comparing_intervention_vs_comparator, Death_or_Major_Traumatic_Injury_30_days_after_Impact_comparing_intervention_vs_comparator, Injury_Severity_Score_30_days_after_Impact_comparing_intervention_vs_comparator, Health_Survey_Score_Total_comparing_intervention_vs_comparator, Health_Survey_Score_Physical_Health_Subscore_comparing_intervention_vs_comparator, Health_Survey_Score_Mental_Health_Subscore_comparing_intervention_vs_comparator, ComparativeEvidence_Bariatric_Surgery_effect_for_ADA_triple_outcome_at_5_years_Diabetes_Surgery_Study, MeanDiffA1c2016metaAnalysis, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Mingrone_2012_DIBASY_trial, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Mingrone_2015_DIBASY_trial, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Parikh_2014, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Courcoulas_2014, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Ding_2015, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Halperin_2014, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Ikramuddin_2013, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Liang_2013, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Schauer_2012_STAMPEDE_trial, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Cummings_2016, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Dixon_2008, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Ikramuddin_2015, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Wentworth_2014, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Courcoulas_2015, ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Schauer_2014_STAMPEDE_trial, AllCauseMortality2022metaAnalysis, Fourteen_day_mortality_remdesivir_vs_placebo_meta_analysis_ACTT_1_Wang_et_al_WHO_SOLIDARITY, Critically_appraised_summary_of_primary_outcome_of_multi_platform_RCT_of_anticoagulation_for_non_critically_ill_patients_with_COVID_19, OutcomeVariable_Nonfatal_myocardial_infarction_or_stroke, OutcomeVariable_Remission_of_diabetes, OutcomeVariable_New_onset_depression, OutcomeVariable_Treatment_with_opioids, OutcomeVariable_Additional_GI_surgical_procedure, Remdesivir, Placebo, Mortality14Day, Investigator_by_treatment_interaction_for_ADAS_Cog11_ANCOVA, Investigator, GroupAssignment_Bariatric_Surgery_vs_no_bariatric_surgery, GroupAssignment_Roux_en_Y_gastric_bypass_vs_medical_treatment, GroupAssignment_Roux_en_Y_gastric_bypass_or_Biliopancreatic_Diversion_vs_medical_treatment, GroupAssignment_Roux_en_Y_gastric_bypass_surgery_vs_Lifestyle_intensive_medical_management_intervention_alone, OutcomeVariable_HbA1c_at_12_months, OutcomeVariable_HbA1c_at_36_months, OutcomeVariable_HbA1c_at_24_months, OutcomeVariable_HbA1c_at_60_months, OutcomeVariable_HbA1c_at_6_months, ExposureVariable_Age_as_continuous_variable, ExposureVariable_Body_Mass_Index_as_continuous_variable, ParticipantFlowMeasure_Exclusion_from_analysis, ParticipantFlowMeasure_Inclusion_in_analysis, ParticipantFlowMeasure_Dropout_due_to_stopping_intervention, Subject_ID, Self_reported_sex, Self_reported_race, Subject_age_at_diagnosis, Sample_ID, Body_site_where_sample_was_collected, Technology_employed_on_the_sample, Analyte_type_of_the_sample, Source_of_sample, The_tumor_status_of_the_sample, GroupAssignment_high_dose_xanomeline_vs_low_dose_xanomeline_vs_placebo, Therapeutic_dose_anticoagulation_with_heparin_vs_Usual_care_pharmacologic_thromboprophylaxis, GroupAssignment_GLP_1_RA_vs_Standard_care, All_cause_mortality313876, Cardiovascular_mortality313877, Nonfatal_myocardial_infarction313878, Nonfatal_stroke313879, End_stage_kidney_disease313880, Heart_failure313881, Serious_hyperglycaemia313882, Severe_gastrointestinal_events313883, Health_related_quality_of_life109569, Body_weight109570, GroupAssignment_SGLT2_inhibitors_vs_GLP_1_RA, All_cause_mortality313956, Cardiovascular_mortality313957, Nonfatal_myocardial_infarction313958, Nonfatal_stroke313959 , End_stage_kidney_disease313960, Heart_failure313961, Diabetic_ketoacidosis313962, Serious_hyperglycaemia313963, Genital_infection313964, Severe_gastrointestinal_events313965, Health_related_quality_of_life109587, Body_weight109588, GroupAssignment_ExposureGroup_JAMA_2018_Norwegian_cohort_study_Surgery_cohort_vs_ComparatorGroup_JAMA_2018_Norwegian_cohort_study_Control_cohort, SEQN, LBXGLU, LBDGLUSI, WTSAF2YR, Median_Age_SD, Age, Sex, Ethnic_Group, Example_Variable_Definition_for_EBMonFHIR_IG, History_of_Broken_Bones, History_of_Acrophobia, History_of_Parachute_Use, Family_History_of_Parachute_Use, Frequent_Flier, International_vs_Domestic_Flight, Example_variable_definition_for_the_EBMonFHIR_IG, Velocity, Altitude, Outcome_Death_or_Major_Traumatic_Injury_on_Impact, Outcome_Injury_Severity_Score_on_Impact, Outcome_Death_or_Major_Traumatic_Injury_30_days_after_Impact, Outcome_Injury_Severity_Score_30_days_after_Impact, Health_Survey_Score_Total, Health_Survey_Score_Physical_Health_Subscore, Health_Survey_Score_Mental_Health_Subscore, Participants_Excluded_from_PARACHUTE_Study, PARACHUTE_Trial_Participants_that_declined_randomization, PARACHUTE_Trial_Participants_deemed_unsuitable_by_investigator, PARACHUTE_Trial_Participants_available_for_randomization, PARACHUTE_Trial_Participants_randomized_into_groups, PARACHUTE_Trial_Participants_that_completed_jump_and_5_minute_follow_up, PARACHUTE_Trial_Participants_with_no_contact_at_30_days, PARACHUTE_Trial_Participants_that_completed_30_day_follow_up, DichotomousIntendedOutcome_Death_or_Major_Traumatic_Injury_within_30_days, GroupAssignment_Non_Participants_vs_Enrolled_Participants, OutcomeVariable_American_Diabetes_Association_composite_triple_end_point_for_metabolic_control_at_5_years, Gender, Condition_code, Ntprobnp_comparator, Ntprobnp_unit, NTproBNP, Birthdate, Ntprobnp_date, Ntprobnp_time, Time_to_integration_of_results_in_a_recommendation, Patient_id, Case_id, OutcomeVariable_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_at_end_of_follow_up, OutcomeVariable_All_cause_mortality, Organ_support_free_days, SearchStrategy_PubMed_and_Embase_search_for_van_Veldhuisen_2022_systematic_review, Standard_care85390_C_85789, Glucagon_Like_Peptide_1_GLP_1_receptor_agonists85390_I_85789, Adults_with_type_2_diabetes_with_moderate_CV_risk, Group/236534, Sodium_Glucose_Transport_Protein_2_SGLT2_inhibitors85394_I_85798, Glucagon_Like_Peptide_1_GLP_1_receptor_agonists85394_C_85798, Adults_with_type_2_diabetes, Group/236948, Group/236949, Year_2018_Norwegian_Cohort_Study, NMA_Diabetes, NCT03421379_FHIR_Transform_M11_IGBJ and CTIS_2024_516402_32_00_FHIR_Transform

Formal Views of Extension Content

Description of Profiles, Differentials, Snapshots, and how the XML and JSON presentations work.

 

Other representations of profile: CSV, Excel, Schematron

Constraints

Id	Grade	Path(s)	Details	Requirements
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()