Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

: Participants_in_Anticoagulation_for_COVID_19_Combined_ATTACC_ACTIV_4a_and_REMAP_CAP_RCT_hospitalized_not_critically_ill - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:_Group ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "7750"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "8" ] ;
fhir:lastUpdated [ fhir:v "2023-12-05T12:59:21.649Z"^^xsd:dateTime ]
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Group</b><a name=\"7750\"> </a><a name=\"hc7750\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceGroup &quot;7750&quot; Version &quot;8&quot; Updated &quot;2023-12-05 12:59:21+0000&quot; </p></div><p><b>Artifact related artifact</b>: </p><p><b>Artifact URL</b>: <a href=\"https://fevir.net/resources/Group/7750\">https://fevir.net/resources/Group/7750</a></p><p><b>Artifact Date</b>: 2022-01-11 17:20:56+0000</p><p><b>Artifact Publisher</b>: Computable Publishing LLC</p><p><b>Artifact Copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><p><b>Artifact Contact</b>: <a href=\"mailto:support@computablepublishing.com\">support@computablepublishing.com</a></p><p><b>Artifact Author</b>: Brian S. Alper: </p><p><b>CombinationMethod</b>: all-of</p><blockquote><p><b>modifierExtension[http://hl7.org/fhir/StructureDefinition/artifact-status]</b></p></blockquote><p><b>identifier</b>: FEvIR Object Identifier/7750</p><p><b>type</b>: person</p><p><b>membership</b>: enumerated</p><p><b>name</b>: Participants_in_Anticoagulation_for_COVID_19_Combined_ATTACC_ACTIV_4a_and_REMAP_CAP_RCT_hospitalized_not_critically_ill</p><p><b>description</b>: An enumerated group participating in a randomized trial.</p><p><b>quantity</b>: 2244</p><blockquote><p><b>characteristic</b></p><p><b>CharacteristicDescription</b>: Participant in the Anticoagulation for COVID-19 Combined (ATTACC, ACTIV-4a, and REMAP-CAP) RCT</p><p><b>code</b>: Research Study for which this is the observed sample <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><p><b>value</b>: <a href=\"Citation-7636.html\">Citation/7636: Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 [Journal Article]. Contributors: The ATTACC, ACTIV-4a, and REMAP-CAP Investigators. In: The New England Journal of Medicine, DOI 10.1056/NEJMoa2105911. Published August 04, 2021. Available at: https://doi.org/10.1056/NEJMoa2105911.</a></p><p><b>exclude</b>: false</p></blockquote><blockquote><p><b>characteristic</b></p><p><b>CharacteristicDescription</b>: Hospitalized</p><p><b>code</b>: Admission to establishment (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#305335007)</span></p><p><b>value</b>: Hospital admission <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#32485007)</span></p><p><b>exclude</b>: false</p></blockquote><blockquote><p><b>characteristic</b></p><p><b>CharacteristicDescription</b>: COVID-19</p><p><b>code</b>: Disease (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#64572001)</span></p><p><b>value</b>: ATTACC and ACTIV-4a limited inclusion to patients with confirmed COVID-19 (and excluded initially entered participants who did not have confirmed SARS-CoV-2. REMAP-CAP however included patients with confirmed COVID-19 or suspected COVID-19 with intent to test for COVID-19. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#840539006 &quot;Disease caused by severe acute respiratory syndrome coronavirus 2 (disorder)&quot;)</span></p><p><b>exclude</b>: false</p></blockquote><blockquote><p><b>characteristic</b></p><p><b>CharacteristicDescription</b>: not critically ill</p><p><b>code</b>: Severity <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#246112005)</span></p><p><b>value</b>: severe disease defined as ICU-level care or critically ill where ICU-level care was defined as the use of respiratory or cardiovascular organ support (oxygen delivered by high-flow nasal cannula, noninvasive or invasive mechanical ventilation, or the use of vasopressors or inotropes) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#442452003 &quot;Life threatening severity&quot;)</span></p><p><b>exclude</b>: true</p></blockquote></div>"
  ] ; # 
  fhir:extension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-relatedArtifact"^^xsd:anyURI ] ;
fhir:value [
a fhir:RelatedArtifact ;
fhir:type [ fhir:v "cite-as" ] ;
fhir:citation [ fhir:v "Participants in Anticoagulation for COVID-19 Combined (ATTACC, ACTIV-4a, and REMAP-CAP) RCT (hospitalized, not critically ill) [Group]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 7750. Revised 2022-01-11. Available at: https://fevir.net/resources/Group/7750. Computable resource at: https://fevir.net/resources/Group/7750." ]     ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-url"^^xsd:anyURI ] ;
fhir:value [ fhir:v "https://fevir.net/resources/Group/7750"^^xsd:anyURI ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-date"^^xsd:anyURI ] ;
fhir:value [ fhir:v "2022-01-11T17:20:56.687Z"^^xsd:dateTime ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-publisher"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Computable Publishing LLC" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-copyright"^^xsd:anyURI ] ;
fhir:value [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/" ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-contact"^^xsd:anyURI ] ;
fhir:value [
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      ( fhir:telecom [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "support@computablepublishing.com" ]       ] )     ]
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fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-author"^^xsd:anyURI ] ;
fhir:value [
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fhir:name [ fhir:v "Brian S. Alper" ]     ]
  ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/combination-method"^^xsd:anyURI ] ;
fhir:value [ fhir:v "all-of" ]
  ] ) ; # 
  fhir:modifierExtension ( [
fhir:url [ fhir:v "http://hl7.org/fhir/StructureDefinition/artifact-status"^^xsd:anyURI ] ;
fhir:value [ fhir:v "active" ]
  ] ) ; # 
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fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ]       ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ]     ] ;
fhir:system [ fhir:v "https://fevir.net"^^xsd:anyURI ] ;
fhir:value [ fhir:v "7750" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ]     ]
  ] ) ; # 
  fhir:type [ fhir:v "person"] ; # 
  fhir:membership [ fhir:v "enumerated"] ; # 
  fhir:name [ fhir:v "Participants_in_Anticoagulation_for_COVID_19_Combined_ATTACC_ACTIV_4a_and_REMAP_CAP_RCT_hospitalized_not_critically_ill"] ; # 
  fhir:description [ fhir:v "An enumerated group participating in a randomized trial."] ; # 
  fhir:quantity [ fhir:v "2244"^^xsd:nonNegativeInteger] ; # 
  fhir:characteristic ( [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/characteristic-description"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Participant in the Anticoagulation for COVID-19 Combined (ATTACC, ACTIV-4a, and REMAP-CAP) RCT" ]     ] ) ;
fhir:code [
fhir:text [ fhir:v "Research Study for which this is the observed sample" ]     ] ;
fhir:value [
a fhir:Reference ;
fhir:reference [ fhir:v "Citation/7636" ] ;
fhir:display [ fhir:v "Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 [Journal Article]. Contributors: The ATTACC, ACTIV-4a, and REMAP-CAP Investigators. In: The New England Journal of Medicine, DOI 10.1056/NEJMoa2105911. Published August 04, 2021. Available at: https://doi.org/10.1056/NEJMoa2105911." ]     ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/characteristic-description"^^xsd:anyURI ] ;
fhir:value [ fhir:v "Hospitalized" ]     ] ) ;
fhir:code [
      ( fhir:coding [
a sct:305335007 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "305335007" ] ;
fhir:display [ fhir:v "Admission to establishment (procedure)" ]       ] )     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
a sct:32485007 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "32485007" ] ;
fhir:display [ fhir:v "Hospital admission" ]       ] )     ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/characteristic-description"^^xsd:anyURI ] ;
fhir:value [ fhir:v "COVID-19" ]     ] ) ;
fhir:code [
      ( fhir:coding [
a sct:64572001 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "64572001" ] ;
fhir:display [ fhir:v "Disease (disorder)" ]       ] )     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
a sct:840539006 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "840539006" ] ;
fhir:display [ fhir:v "Disease caused by severe acute respiratory syndrome coronavirus 2 (disorder)" ]       ] ) ;
fhir:text [ fhir:v "ATTACC and ACTIV-4a limited inclusion to patients with confirmed COVID-19 (and excluded initially entered participants who did not have confirmed SARS-CoV-2. REMAP-CAP however included patients with confirmed COVID-19 or suspected COVID-19 with intent to test for COVID-19." ]     ] ;
fhir:exclude [ fhir:v "false"^^xsd:boolean ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/characteristic-description"^^xsd:anyURI ] ;
fhir:value [ fhir:v "not critically ill" ]     ] ) ;
fhir:code [
      ( fhir:coding [
a sct:246112005 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "246112005" ] ;
fhir:display [ fhir:v "Severity" ]       ] )     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
a sct:442452003 ;
fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
fhir:code [ fhir:v "442452003" ] ;
fhir:display [ fhir:v "Life threatening severity" ]       ] ) ;
fhir:text [ fhir:v "severe disease defined as ICU-level care or critically ill where ICU-level care was defined as the use of respiratory or cardiovascular organ support (oxygen delivered by high-flow nasal cannula, noninvasive or invasive mechanical ventilation, or the use of vasopressors or inotropes)" ]     ] ;
fhir:exclude [ fhir:v "true"^^xsd:boolean ]
  ] ) . #