NetEffectContribution: New onset depression for Example for GIN 2022 - TTL Representation - Evidence Based Medicine on FHIR Implementation Guide v1.0.0-ballot

Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
: NetEffectContribution: New onset depression for Example for GIN 2022 - TTL Representation

Active as of 2024-05-16
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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Evidence ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "179589"] ; # 
  fhir:meta [
fhir:versionId [ fhir:v "4" ] ;
fhir:lastUpdated [ fhir:v "2023-12-08T13:31:50.403Z"^^xsd:dateTime ] ;
    ( fhir:profile [
fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution"^^xsd:anyURI ;
fhir:link <http://hl7.org/fhir/uv/ebm/StructureDefinition/net-effect-contribution>     ] )
  ] ; # 
  fhir:text [
fhir:status [ fhir:v "extensions" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: Evidence</b><a name=\"179589\"> </a><a name=\"hc179589\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidence &quot;179589&quot; Version &quot;4&quot; Updated &quot;2023-12-08 13:31:50+0000&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-net-effect-contribution.html\">NetEffectContribution</a></p></div><p><b>url</b>: <code>https://fevir.net/resources/Evidence/179589</code></p><p><b>identifier</b>: FEvIR Object Identifier/179589</p><p><b>version</b>: 1.0.0-ballot</p><p><b>name</b>: NetEffectContribution_New_onset_depression_for_Example_for_GIN_2022</p><p><b>title</b>: NetEffectContribution: New onset depression for Example for GIN 2022</p><p><b>status</b>: active</p><p><b>date</b>: 2024-05-16 12:17:54+0000</p><p><b>publisher</b>: HL7 International / Clinical Decision Support</p><p><b>contact</b>: HL7 International / Clinical Decision Support: <a href=\"http://www.hl7.org/Special/committees/dss\">http://www.hl7.org/Special/committees/dss</a></p><p><b>author</b>: Brian S. Alper: </p><h3>UseContexts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Evidence Communication (Details: Evidence Based Medicine on FHIR Implementation Guide Code System code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')</td><td>ComparativeEvidence <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#ComparativeEvidence)</span></td></tr><tr><td style=\"display: none\">*</td><td>Evidence Communication (Details: Evidence Based Medicine on FHIR Implementation Guide Code System code evidence-communication = 'Evidence Communication', stated as 'Evidence Communication')</td><td>NetEffectContribution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#NetEffectContribution)</span></td></tr></table><p><b>copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Citation</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>cite-as</td><td>NetEffectContribution: New onset depression for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179589. Revised 2023-12-04. Available at: https://fevir.net/resources/Evidence/179589. Computable resource at: https://fevir.net/resources/Evidence/179589.</td><td> </td></tr><tr><td style=\"display: none\">*</td><td>amended-with</td><td> </td><td><a href=\"ArtifactAssessment-104194.html\">ArtifactAssessment/104194: Outcome Importance Rating (default value 5) of New onset depression</a></td></tr></table><p><b>description</b>: -0.16 (-0.23 to -0.13)</p><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: population</p><p><b>description</b>: Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included).</p><p><b>note</b>: population</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#population &quot;population&quot;)</span></p><p><b>observed</b>: <a href=\"Group-178427.html\">Group/178427: StudyGroup: Severely Obese Adults 2018 Norwegian Cohort</a> &quot;Severely_Obese_Adults_2018_Norwegian_Cohort&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: exposure</p><p><b>VariableDefinitionComparatorCategory</b>: no bariatric surgery</p><p><b>description</b>: comparison groups of bariatric surgery vs. no bariatric surgery</p><p><b>note</b>: exposure</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#exposure &quot;exposure&quot;)</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-172427.html\">EvidenceVariable/172427: GroupAssignment: Bariatric Surgery vs. no bariatric surgery</a> &quot;GroupAssignment_Bariatric_Surgery_vs_no_bariatric_surgery&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: outcome</p><p><b>description</b>: New onset depression</p><p><b>note</b>: outcome</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#measuredVariable &quot;measured variable&quot;)</span></p><p><b>observed</b>: <a href=\"EvidenceVariable-104118.html\">EvidenceVariable/104118: OutcomeVariable: New onset depression</a> &quot;OutcomeVariable_New_onset_depression&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>VariableDefinitionVariableRoleCode</b>: covariate</p><p><b>VariableDefinitionRoleSubtype</b>: Relative importance multiplier <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-179423.html\">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#importance-multiplier)</span></p><p><b>description</b>: Relative Importance Multiplier</p><p><b>note</b>: covariate</p><p><b>variableRole</b>: Use extension:variableRoleCode instead. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#confounder &quot;confounder&quot;)</span></p><p><b>observed</b>: <span>: Relative Importance Multiplier</span></p></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: risk difference -0.16 (95% CI -0.23 to -0.13)</p><p><b>statisticType</b>: Risk Difference <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#STATO:0000424)</span></p><p><b>quantity</b>: -0.16</p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Description</b></td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>95% CI -0.23 to -0.13</td><td>confidence interval <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#STATO:0000196)</span></td><td>0.95</td><td>-0.23--0.13</td></tr></table><h3>ModelCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td>Net effect contribution analysis <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-181513.html\">Scientific Evidence Code System (SEVCO) -- EXAMPLE VERSION for EBMonFHIR Implementation Guide</a>#TBD:net-effect-contribution-analysis)</span></td></tr></table></blockquote></div>"
  ] ; # 
  fhir:url [ fhir:v "https://fevir.net/resources/Evidence/179589"^^xsd:anyURI] ; # 
  fhir:identifier ( [
fhir:type [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v2-0203"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ACSN" ] ;
fhir:display [ fhir:v "Accession ID" ]       ] ) ;
fhir:text [ fhir:v "FEvIR Object Identifier" ]     ] ;
fhir:system [ fhir:v "https://fevir.net"^^xsd:anyURI ] ;
fhir:value [ fhir:v "179589" ] ;
fhir:assigner [
fhir:display [ fhir:v "Computable Publishing LLC" ]     ]
  ] ) ; # 
  fhir:version [ fhir:v "1.0.0-ballot"] ; # 
  fhir:name [ fhir:v "NetEffectContribution_New_onset_depression_for_Example_for_GIN_2022"] ; # 
  fhir:title [ fhir:v "NetEffectContribution: New onset depression for Example for GIN 2022"] ; # 
  fhir:status [ fhir:v "active"] ; # 
  fhir:date [ fhir:v "2024-05-16T12:17:54+00:00"^^xsd:dateTime] ; # 
  fhir:publisher [ fhir:v "HL7 International / Clinical Decision Support"] ; # 
  fhir:contact ( [
fhir:name [ fhir:v "HL7 International / Clinical Decision Support" ] ;
    ( fhir:telecom [
fhir:system [ fhir:v "url" ] ;
fhir:value [ fhir:v "http://www.hl7.org/Special/committees/dss" ]     ] )
  ] ) ; # 
  fhir:author ( [
fhir:name [ fhir:v "Brian S. Alper" ]
  ] ) ; # 
  fhir:useContext ( [
fhir:code [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "evidence-communication" ] ;
fhir:display [ fhir:v "Evidence Communication" ]     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "ComparativeEvidence" ] ;
fhir:display [ fhir:v "ComparativeEvidence" ]       ] )     ]
  ] [
fhir:code [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "evidence-communication" ] ;
fhir:display [ fhir:v "Evidence Communication" ]     ] ;
fhir:value [
a fhir:CodeableConcept ;
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "NetEffectContribution" ] ;
fhir:display [ fhir:v "NetEffectContribution" ]       ] )     ]
  ] ) ; # 
  fhir:copyright [ fhir:v "https://creativecommons.org/licenses/by-nc-sa/4.0/"] ; # 
  fhir:relatedArtifact ( [
fhir:type [ fhir:v "cite-as" ] ;
fhir:citation [ fhir:v "NetEffectContribution: New onset depression for Example for GIN 2022 [Evidence]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179589. Revised 2023-12-04. Available at: https://fevir.net/resources/Evidence/179589. Computable resource at: https://fevir.net/resources/Evidence/179589." ]
  ] [
fhir:type [ fhir:v "amended-with" ] ;
fhir:resourceReference [
fhir:reference [ fhir:v "ArtifactAssessment/104194" ] ;
fhir:type [ fhir:v "ArtifactAssessment"^^xsd:anyURI ] ;
fhir:display [ fhir:v "Outcome Importance Rating (default value 5) of New onset depression" ]     ]
  ] ) ; # 
  fhir:description [ fhir:v "-0.16 (-0.23 to -0.13)"] ; # 
  fhir:variableDefinition ( [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code"^^xsd:anyURI ] ;
fhir:value [ fhir:v "population" ]     ] ) ;
fhir:description [ fhir:v "Cohort study with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included)." ] ;
    ( fhir:note [
fhir:text [ fhir:v "population" ]     ] ) ;
fhir:variableRole [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "population" ] ;
fhir:display [ fhir:v "population" ]       ] ) ;
fhir:text [ fhir:v "Use extension:variableRoleCode instead." ]     ] ;
fhir:observed [
fhir:reference [ fhir:v "Group/178427" ] ;
fhir:type [ fhir:v "Group"^^xsd:anyURI ] ;
fhir:display [ fhir:v "StudyGroup: Severely Obese Adults 2018 Norwegian Cohort" ]     ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code"^^xsd:anyURI ] ;
fhir:value [ fhir:v "exposure" ]     ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-comparator-category"^^xsd:anyURI ] ;
fhir:value [ fhir:v "no bariatric surgery" ]     ] ) ;
fhir:description [ fhir:v "comparison groups of bariatric surgery vs. no bariatric surgery" ] ;
    ( fhir:note [
fhir:text [ fhir:v "exposure" ]     ] ) ;
fhir:variableRole [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "exposure" ] ;
fhir:display [ fhir:v "exposure" ]       ] ) ;
fhir:text [ fhir:v "Use extension:variableRoleCode instead." ]     ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/172427" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "GroupAssignment: Bariatric Surgery vs. no bariatric surgery" ]     ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code"^^xsd:anyURI ] ;
fhir:value [ fhir:v "outcome" ]     ] ) ;
fhir:description [ fhir:v "New onset depression" ] ;
    ( fhir:note [
fhir:text [ fhir:v "outcome" ]     ] ) ;
fhir:variableRole [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "measuredVariable" ] ;
fhir:display [ fhir:v "measured variable" ]       ] ) ;
fhir:text [ fhir:v "Use extension:variableRoleCode instead." ]     ] ;
fhir:observed [
fhir:reference [ fhir:v "EvidenceVariable/104118" ] ;
fhir:type [ fhir:v "EvidenceVariable"^^xsd:anyURI ] ;
fhir:display [ fhir:v "OutcomeVariable: New onset depression" ]     ]
  ] [
    ( fhir:extension [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-variable-role-code"^^xsd:anyURI ] ;
fhir:value [ fhir:v "covariate" ]     ] [
fhir:url [ fhir:v "http://hl7.org/fhir/uv/ebm/StructureDefinition/variable-definition-role-subtype"^^xsd:anyURI ] ;
fhir:value [
a fhir:CodeableConcept ;
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/179423"^^xsd:anyURI ] ;
fhir:code [ fhir:v "importance-multiplier" ] ;
fhir:display [ fhir:v "Relative importance multiplier" ]         ] )       ]     ] ) ;
fhir:description [ fhir:v "Relative Importance Multiplier" ] ;
    ( fhir:note [
fhir:text [ fhir:v "covariate" ]     ] ) ;
fhir:variableRole [
      ( fhir:coding [
fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/variable-role"^^xsd:anyURI ] ;
fhir:code [ fhir:v "confounder" ] ;
fhir:display [ fhir:v "confounder" ]       ] ) ;
fhir:text [ fhir:v "Use extension:variableRoleCode instead." ]     ] ;
fhir:observed [
fhir:display [ fhir:v "Relative Importance Multiplier" ]     ]
  ] ) ; # 
  fhir:statistic ( [
fhir:description [ fhir:v "risk difference -0.16 (95% CI -0.23 to -0.13)" ] ;
fhir:statisticType [
      ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/181513"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000424" ] ;
fhir:display [ fhir:v "Risk Difference" ]       ] )     ] ;
fhir:quantity [
fhir:value [ fhir:v "-0.16"^^xsd:decimal ]     ] ;
    ( fhir:attributeEstimate [
fhir:description [ fhir:v "95% CI -0.23 to -0.13" ] ;
fhir:type [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/181513"^^xsd:anyURI ] ;
fhir:code [ fhir:v "STATO:0000196" ] ;
fhir:display [ fhir:v "confidence interval" ]         ] )       ] ;
fhir:level [ fhir:v "0.95"^^xsd:decimal ] ;
fhir:range [
fhir:low [
fhir:value [ fhir:v "-0.23"^^xsd:decimal ]         ] ;
fhir:high [
fhir:value [ fhir:v "-0.13"^^xsd:decimal ]         ]       ]     ] ) ;
    ( fhir:modelCharacteristic [
fhir:code [
        ( fhir:coding [
fhir:system [ fhir:v "https://fevir.net/resources/CodeSystem/181513"^^xsd:anyURI ] ;
fhir:code [ fhir:v "TBD:net-effect-contribution-analysis" ] ;
fhir:display [ fhir:v "Net effect contribution analysis" ]         ] )       ]     ] )
  ] ) . #