Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot
Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions
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<div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Composition</b><a name="104383"> </a><a name="hc104383"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceComposition "104383" Version "26" Updated "2024-04-27 18:38:02+0000" </p><p style="margin-bottom: 0px">Profiles: <a href="StructureDefinition-summary-of-net-effect.html">SummaryOfNetEffect</a>, <a href="StructureDefinition-evidence-report.html">EvidenceReport</a></p></div><p><b>Artifact Description</b>: Example of SummaryOfNetEffect Profile of Composition Resource.</p><p><b>url</b>: <a href="https://fevir.net/resources/Composition/104383">https://fevir.net/resources/Composition/104383</a></p><p><b>identifier</b>: FEvIR Object Identifier/104383</p><p><b>status</b>: final</p><p><b>type</b>: EvidenceReport <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-179423.html">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#EvidenceReport)</span></p><p><b>category</b>: Summary of Net Effect Contributions <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-179423.html">Evidence Based Medicine on FHIR Implementation Guide Code System</a>#SummaryOfNetEffect "SummaryOfNetEffect")</span></p><p><b>date</b>: 2024-04-27 18:38:02+0000</p><p><b>author</b>: <span>: Brian S. Alper</span></p><p><b>title</b>: SummaryOfNetEffect: Bariatric Surgery Summary of Net Effect Contributions Example for GIN 2022</p><p><b>custodian</b>: <span>: Computable Publishing LLC</span></p><blockquote><p><b>relatesTo</b></p><p><b>type</b>: supported-with</p><p><b>label</b>: Copyright</p><blockquote><p><b>document</b></p></blockquote></blockquote><blockquote><p><b>relatesTo</b></p><p><b>type</b>: cite-as</p><p><b>citation</b>: SummaryOfNetEffect: Bariatric Surgery Summary of Net Effect Contributions Example for GIN 2022 [Database Entry: FHIR Composition Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 104383. Revised 2023-12-05. Available at: https://fevir.net/resources/Composition/104383. Computable resource at: https://fevir.net/resources/Composition/104383.</p></blockquote></div>
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<reference value="ArtifactAssessment/104064"/>
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<div xmlns="http://www.w3.org/1999/xhtml">100</div>
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<div xmlns="http://www.w3.org/1999/xhtml">-2.25%</div>
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<entry>🔗
<reference value="Evidence/49328"/>
<type value="Evidence"/>
<display
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<div xmlns="http://www.w3.org/1999/xhtml">2.14 (1.8 to 2.42)</div>
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<entry>🔗
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<reference value="EvidenceVariable/104097"/>
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<display
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<div xmlns="http://www.w3.org/1999/xhtml">Nonfatal myocardial infarction or stroke</div>
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<entry>🔗
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<display value="Outcome Desirability"/>
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<text value="Outcome Desirability"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Undesirable</div>
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<entry>🔗
<reference value="ArtifactAssessment/104192"/>
<type value="ArtifactAssessment"/>
<display
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<section>
<title value="Relative Importance"/>
<code>
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<text value="Relative Importance"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">30</div>
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<entry>🔗
<reference value="ArtifactAssessment/104192"/>
<type value="ArtifactAssessment"/>
<display
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<title value="Result Without Treatment"/>
<code>
<coding>
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<display value="Result with comparator alone"/>
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<text>
<status value="additional"/>
<div xmlns="http://www.w3.org/1999/xhtml">9.2%</div>
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<div xmlns="http://www.w3.org/1999/xhtml">6.2%</div>
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<entry>
<display
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<entry>🔗
<reference value="Evidence/104098"/>
<type value="Evidence"/>
<display
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<title value="Effect Estimate"/>
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<coding>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">-3%</div>
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<entry>🔗
<reference value="Evidence/104098"/>
<type value="Evidence"/>
<display
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<code>
<coding>
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<display value="Net Effect Contribution"/>
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<text value="Net Effect Contribution"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">0.91 (0.47 to 1.27)</div>
</text>
<entry>🔗
<reference value="Evidence/179587"/>
<type value="Evidence"/>
<display
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<title value="Remission of diabetes"/>
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<focus>🔗
<reference value="EvidenceVariable/104117"/>
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<display value="OutcomeDefinition: Remission of diabetes"/>
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<div xmlns="http://www.w3.org/1999/xhtml">Remission of diabetes</div>
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<entry>🔗
<reference value="EvidenceVariable/104117"/>
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<text value="Outcome Desirability"/>
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<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Desirable</div>
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<entry>🔗
<reference value="ArtifactAssessment/104193"/>
<type value="ArtifactAssessment"/>
<display
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<title value="Relative Importance"/>
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<code value="relative-importance"/>
<display value="Relative Importance"/>
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<text value="Relative Importance"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">5</div>
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<entry>🔗
<reference value="ArtifactAssessment/104193"/>
<type value="ArtifactAssessment"/>
<display
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<title value="Result Without Treatment"/>
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<coding>
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<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
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<text>
<status value="additional"/>
<div xmlns="http://www.w3.org/1999/xhtml">14.8%</div>
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<section>
<title value="Result With Treatment--Derived"/>
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<text
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">57.7%</div>
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<entry>
<display
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</entry>
<entry>🔗
<reference value="Evidence/104121"/>
<type value="Evidence"/>
<display
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<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">42.9%</div>
</text>
<entry>🔗
<reference value="Evidence/104121"/>
<type value="Evidence"/>
<display
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<section>
<title value="Net Effect Contribution"/>
<code>
<coding>
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<code value="net-effect-contribution"/>
<display value="Net Effect Contribution"/>
</coding>
<text value="Net Effect Contribution"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">2.15 (1.33 to 3.26)</div>
</text>
<entry>🔗
<reference value="Evidence/179588"/>
<type value="Evidence"/>
<display
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</section>
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<section>
<title value="New onset depression"/>
<code>
<coding>
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<code
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<focus>🔗
<reference value="EvidenceVariable/104118"/>
<type value="EvidenceVariable"/>
<display value="OutcomeDefinition: New onset depression"/>
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<title value="Outcome"/>
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<coding>
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<display value="Outcome Measure"/>
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<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">New onset depression</div>
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<entry>🔗
<reference value="EvidenceVariable/104118"/>
<type value="EvidenceVariable"/>
<display value="OutcomeDefinition: New onset depression"/>
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<section>
<title value="Desirability"/>
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<code value="outcome-desirability"/>
<display value="Outcome Desirability"/>
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<text value="Outcome Desirability"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Undesirable</div>
</text>
<entry>🔗
<reference value="ArtifactAssessment/104194"/>
<type value="ArtifactAssessment"/>
<display
value="Outcome Importance Rating (default value 5) of New onset depression"/>
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<section>
<title value="Relative Importance"/>
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<code value="relative-importance"/>
<display value="Relative Importance"/>
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<text value="Relative Importance"/>
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<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">5</div>
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<entry>🔗
<reference value="ArtifactAssessment/104194"/>
<type value="ArtifactAssessment"/>
<display
value="Outcome Importance Rating (default value 5) of New onset depression"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="additional"/>
<div xmlns="http://www.w3.org/1999/xhtml">6.5%</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">9.75%</div>
</text>
<entry>
<display
value="62 events in 956 participants (6.5%) in control group"/>
</entry>
<entry>🔗
<reference value="Evidence/104155"/>
<type value="Evidence"/>
<display
value="StudyOutcomeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">3.25%</div>
</text>
<entry>🔗
<reference value="Evidence/104155"/>
<type value="Evidence"/>
<display
value="StudyOutcomeEvidence: Bypass surgery effects on New onset depression in JAMA 2018 Norwegian cohort study"/>
</entry>
</section>
<section>
<title value="Net Effect Contribution"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="net-effect-contribution"/>
<display value="Net Effect Contribution"/>
</coding>
<text value="Net Effect Contribution"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">-0.16 (-0.23 to -0.13)</div>
</text>
<entry>🔗
<reference value="Evidence/179589"/>
<type value="Evidence"/>
<display
value="NetEffectContribution: New onset depression for Example for GIN 2022"/>
</entry>
</section>
</section>
<section>
<title value="Treatment with opioids"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code
value="summary-of-net-effect-contributions-entry-for-a-single-outcome"/>
<display
value="Summary of net effect contributions entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/104119"/>
<type value="EvidenceVariable"/>
<display value="OutcomeDefinition: Treatment with opioids"/>
</focus>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Treatment with opioids</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/104119"/>
<type value="EvidenceVariable"/>
<display value="OutcomeDefinition: Treatment with opioids"/>
</entry>
</section>
<section>
<title value="Desirability"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-desirability"/>
<display value="Outcome Desirability"/>
</coding>
<text value="Outcome Desirability"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Undesirable</div>
</text>
<entry>🔗
<reference value="ArtifactAssessment/104195"/>
<type value="ArtifactAssessment"/>
<display
value="Outcome Importance Rating (default value 5) of Treatment with opioids"/>
</entry>
</section>
<section>
<title value="Relative Importance"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="relative-importance"/>
<display value="Relative Importance"/>
</coding>
<text value="Relative Importance"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">5</div>
</text>
<entry>🔗
<reference value="ArtifactAssessment/104195"/>
<type value="ArtifactAssessment"/>
<display
value="Outcome Importance Rating (default value 5) of Treatment with opioids"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="additional"/>
<div xmlns="http://www.w3.org/1999/xhtml">15.8%</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">20.5%</div>
</text>
<entry>
<display
value="151 events in 956 participants (15.8%) in control group"/>
</entry>
<entry>🔗
<reference value="Evidence/104156"/>
<type value="Evidence"/>
<display
value="StudyOutcomeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">4.7%</div>
</text>
<entry>🔗
<reference value="Evidence/104156"/>
<type value="Evidence"/>
<display
value="StudyOutcomeEvidence: Bypass surgery effects on Treatment with opioids in JAMA 2018 Norwegian cohort study"/>
</entry>
</section>
<section>
<title value="Net Effect Contribution"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="net-effect-contribution"/>
<display value="Net Effect Contribution"/>
</coding>
<text value="Net Effect Contribution"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">-0.24 (-0.32 to -01.6)</div>
</text>
<entry>🔗
<reference value="Evidence/179590"/>
<type value="Evidence"/>
<display
value="NetEffectContribution: Treatment with opioids for Example for GIN 2022"/>
</entry>
</section>
</section>
<section>
<title value="Additional GI surgical procedure"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code
value="summary-of-net-effect-contributions-entry-for-a-single-outcome"/>
<display
value="Summary of net effect contributions entry for a single outcome"/>
</coding>
</code>
<focus>🔗
<reference value="EvidenceVariable/104120"/>
<type value="EvidenceVariable"/>
<display value="OutcomeDefinition: Additional GI surgical procedure"/>
</focus>
<section>
<title value="Outcome"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-measure"/>
<display value="Outcome Measure"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Additional GI surgical procedure</div>
</text>
<entry>🔗
<reference value="EvidenceVariable/104120"/>
<type value="EvidenceVariable"/>
<display value="OutcomeDefinition: Additional GI surgical procedure"/>
</entry>
</section>
<section>
<title value="Desirability"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="outcome-desirability"/>
<display value="Outcome Desirability"/>
</coding>
<text value="Outcome Desirability"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Undesirable</div>
</text>
<entry>🔗
<reference value="ArtifactAssessment/104196"/>
<type value="ArtifactAssessment"/>
<display
value="Outcome Importance Rating (default value 8) of Additional GI surgical procedure"/>
</entry>
</section>
<section>
<title value="Relative Importance"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="relative-importance"/>
<display value="Relative Importance"/>
</coding>
<text value="Relative Importance"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">8</div>
</text>
<entry>🔗
<reference value="ArtifactAssessment/104196"/>
<type value="ArtifactAssessment"/>
<display
value="Outcome Importance Rating (default value 8) of Additional GI surgical procedure"/>
</entry>
</section>
<section>
<title value="Result Without Treatment"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-comparator-alone"/>
<display value="Result with comparator alone"/>
</coding>
</code>
<text>
<status value="additional"/>
<div xmlns="http://www.w3.org/1999/xhtml">15.5%</div>
</text>
</section>
<section>
<title value="Result With Treatment--Derived"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-alone-calculated"/>
<display value="Result with intervention alone (calculated)"/>
</coding>
<text
value="calculated value derived from the control group and effect estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">31%</div>
</text>
<entry>
<display
value="148 events in 956 participants (15.5%) in control group"/>
</entry>
<entry>🔗
<reference value="Evidence/104157"/>
<type value="Evidence"/>
<display
value="StudyOutcomeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"/>
</entry>
</section>
<section>
<title value="Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="result-with-intervention-vs-comparator"/>
<display value="Result with intervention vs. comparator"/>
</coding>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">15.5%</div>
</text>
<entry>🔗
<reference value="Evidence/104157"/>
<type value="Evidence"/>
<display
value="StudyOutcomeEvidence: Bypass surgery effects on Additional GI surgical procedure in JAMA 2018 Norwegian cohort study"/>
</entry>
</section>
<section>
<title value="Net Effect Contribution"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="net-effect-contribution"/>
<display value="Net Effect Contribution"/>
</coding>
<text value="Net Effect Contribution"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">-1.24 (-1.74 to -0.87)</div>
</text>
<entry>🔗
<reference value="Evidence/179591"/>
<type value="Evidence"/>
<display
value="NetEffectContribution: Additional GI surgical procedure for Example for GIN 2022"/>
</entry>
</section>
</section>
<section>
<title value="Net Effect Estimate"/>
<code>
<coding>
<system value="https://fevir.net/resources/CodeSystem/179423"/>
<code value="net-effect-estimate"/>
<display value="Net Effect Estimate"/>
</coding>
<text value="Net Effect Point Estimate"/>
</code>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml">Net Effect Estimate = 3.55 (2.38 to 4.73)</div>
</text>
<entry>🔗
<reference value="Evidence/179583"/>
<type value="Evidence"/>
<display
value="NetEffectEstimate: Bariatric Surgery Example for GIN 2022"/>
</entry>
</section>
</Composition>
IG © 2022+ HL7 International / Clinical Decision Support. Package hl7.fhir.uv.ebm#1.0.0-ballot based on FHIR 5.0.0. Generated 2024-05-17
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