Evidence Based Medicine on FHIR Implementation Guide
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Evidence Based Medicine on FHIR Implementation Guide, published by HL7 International / Clinical Decision Support. This guide is not an authorized publication; it is the continuous build for version 1.0.0-ballot built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/ebm/ and changes regularly. See the Directory of published versions

Example Citation: StudyCitation: 2022 Systematic Review of bariatric surgery mortality effect 35243488

Active as of 2022-05-28

Generated Narrative: Citation

Resource Citation "33400" Version "6" Updated "2023-12-01 10:35:34+0000"

url: https://fevir.net/resources/Citation/33400

identifier: FEvIR Object Identifier/33400, https://pubmed.ncbi.nlm.nih.gov/35243488

version: 1.0.0-ballot

title: StudyCitation: 2022 Systematic Review of bariatric surgery mortality effect 35243488

status: active

date: 2022-05-28 12:27:14+0000

publisher: HL7 International / Clinical Decision Support

contact: HL7 International / Clinical Decision Support: http://www.hl7.org/Special/committees/dss

description: This Citation Resource is referenced in an example for the EBMonFHIR Implementation Guide.

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copyright: https://creativecommons.org/licenses/by-nc-sa/4.0/

lastReviewDate: 2022-03-10

author: Brian S. Alper:

Summaries

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*Computable Publishing (Citation Summary Style#comppub)Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis [Journal Article]. Contributors: van Veldhuisen SL, Gorter TM, van Woerden G, de Boer RA, Rienstra M, Hazebroek EJ, van Veldhuisen DJ. In: European heart journal, PMID 35243488. Published March 04, 2022. Available at: https://pubmed.ncbi.nlm.nih.gov/35243488/.

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identifier: https://pubmed.ncbi.nlm.nih.gov/35243488, https://www.ncbi.nlm.nih.gov/pmc//PMC9123239, https://doi.org/10.1093/eurheartj/ehac071, pii/6542137

Titles

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*Primary title (Title Type#primary)English (Tags for the Identification of Languages#en)Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis.

Abstracts

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***AIMS:** Obesity is a global health problem, associated with significant morbidity and mortality, often due to cardiovascular (CV) diseases. While bariatric surgery is increasingly performed in patients with obesity and reduces CV risk factors, its effect on CV disease is not established. We conducted a systematic review and meta-analysis to evaluate the effect of bariatric surgery on CV outcomes, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. **METHODS AND RESULTS:** PubMed and Embase were searched for literature until August 2021 which compared bariatric surgery patients to non-surgical controls. Outcomes of interest were all-cause and CV mortality, atrial fibrillation (AF), heart failure (HF), myocardial infarction, and stroke. We included 39 studies, all prospective or retrospective cohort studies, but randomized outcome trials were not available. Bariatric surgery was associated with a beneficial effect on all-cause mortality [pooled hazard ratio (HR) of 0.55; 95% confidence interval (CI) 0.49-0.62, P < 0.001 vs. controls], and CV mortality (HR 0.59, 95% CI 0.47-0.73, P < 0.001). In addition, bariatric surgery was also associated with a reduced incidence of HF (HR 0.50, 95% CI 0.38-0.66, P < 0.001), myocardial infarction (HR 0.58, 95% CI 0.43-0.76, P < 0.001), and stroke (HR 0.64, 95% CI 0.53-0.77, P < 0.001), while its association with AF was not statistically significant (HR 0.82, 95% CI 0.64-1.06, P = 0.12). **CONCLUSION:** The present systematic review and meta-analysis suggests that bariatric surgery is associated with reduced all-cause and CV mortality, and lowered incidence of several CV diseases in patients with obesity. Bariatric surgery should therefore be considered in these patients.© The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Cardiology.

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