Pharmaceutical Quality - Chemistry, Manufacturing and Controls (PQ-CMC) Submissions to FDA
2.0.0 - STU2

Pharmaceutical Quality - Chemistry, Manufacturing and Controls (PQ-CMC) Submissions to FDA, published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 2.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/FHIR-us-pq-cmc-fda/ and changes regularly. See the Directory of published versions

## : 3.2.P.3.2 Bundle for two-layer tablet - TTL Representation

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    @prefix fhir: <http://hl7.org/fhir/> .
    @prefix owl: <http://www.w3.org/2002/07/owl#> .
    @prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
    @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
    @prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

    # - resource -------------------------------------------------------------------

     a fhir:Bundle ;
      fhir:nodeRole fhir:treeRoot ;
      fhir:id [ fhir:v "BatchFormulaBundle2Layer"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-ectd-document-32p32"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-ectd-document-32p32>     ] )
      ] ; #
      fhir:identifier [
    fhir:system [ fhir:v "urn:ietf:rfc:3986"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "urn:uuid:49d3b79e-b436-a242-93ba-b706b4364ab2" ]
      ] ; #
      fhir:type [ fhir:v "document"] ; #
      fhir:timestamp [ fhir:v "2024-08-29T12:34:56.789Z"^^xsd:dateTime] ; #
      fhir:entry ( [
    fhir:fullUrl [ fhir:v "urn:uuid:c00b0003-c2bf-7547-8b1c-f1f399f99d5c"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:c00b0003-c2bf-7547-8b1c-f1f399f99d5c> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4f3e9af1-306b-4fad-bf04-7881400b266a"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4f3e9af1-306b-4fad-bf04-7881400b266a> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:b69435a0-45c6-4d44-9fde-b354e17408d7"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:b69435a0-45c6-4d44-9fde-b354e17408d7> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:f0f3ff35-5cfa-6617-b8f1-b8167957f53c"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:f0f3ff35-5cfa-6617-b8f1-b8167957f53c> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:8a3e11d9-4323-43c4-be00-8f0ea1837070"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:8a3e11d9-4323-43c4-be00-8f0ea1837070> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:d4713a90-38d1-49e5-a977-78c63e518562"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:d4713a90-38d1-49e5-a977-78c63e518562> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:fbd464cc-2511-4a3a-b058-3cec4fffd14f"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:fbd464cc-2511-4a3a-b058-3cec4fffd14f> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:9973ba9a-b257-425a-8fb9-6dcfe379ca08"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:9973ba9a-b257-425a-8fb9-6dcfe379ca08> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4e394a0c-4b25-492e-aac7-0faf121ffc4f"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4e394a0c-4b25-492e-aac7-0faf121ffc4f> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:95648837-ec81-42d9-970c-eac390f2f604"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:95648837-ec81-42d9-970c-eac390f2f604> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:cbb54715-3928-4e3f-9abe-32914f694957"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:cbb54715-3928-4e3f-9abe-32914f694957> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:ca1ff85f-3f05-46be-8cc4-30b076d88c13"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:ca1ff85f-3f05-46be-8cc4-30b076d88c13> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:99f4a24f-880f-45f1-8364-8e4e03977b2e"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:99f4a24f-880f-45f1-8364-8e4e03977b2e> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:a4624559-6c4f-4e90-996d-bc3bf2f5a3f4"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:a4624559-6c4f-4e90-996d-bc3bf2f5a3f4> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:254742fb-7b5b-49f5-b4af-e0d14d81f2f6"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:254742fb-7b5b-49f5-b4af-e0d14d81f2f6> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:4b565cf3-5353-48af-8cd6-5ccf4e9fd579"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:4b565cf3-5353-48af-8cd6-5ccf4e9fd579> )
      ] [
    fhir:fullUrl [ fhir:v "urn:uuid:e165f057-5eed-4e64-8328-4438fc88fb1b"^^xsd:anyURI ] ;
        ( fhir:resource <urn:uuid:e165f057-5eed-4e64-8328-4438fc88fb1b> )
      ] ) . #

    <urn:uuid:c00b0003-c2bf-7547-8b1c-f1f399f99d5c> a fhir:Composition ;
      fhir:id [ fhir:v "c00b0003-c2bf-7547-8b1c-f1f399f99d5c"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/ectd-composition-32p32"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/ectd-composition-32p32>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Composition_c00b0003-c2bf-7547-8b1c-f1f399f99d5c\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Composition c00b0003-c2bf-7547-8b1c-f1f399f99d5c</b></p><a name=\"c00b0003-c2bf-7547-8b1c-f1f399f99d5c\"> </a><a name=\"hcc00b0003-c2bf-7547-8b1c-f1f399f99d5c\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ectd-composition-32p32.html\">eCTD Batch Formula</a></p></div><p><b>identifier</b>: BatchFormulaComposition2layer</p><p><b>status</b>: Final</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/ICHContextOfUse ich_3.2.p.3.2}\">m3.2.p.3.2 batch formula</span></p><p><b>date</b>: 2024-08-01 12:34:56+0000</p><p><b>author</b>: <a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-4f3e9af1-306b-4fad-bf04-7881400b266a\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></p><p><b>title</b>: Batch formula example two layer tablet</p></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:value [ fhir:v "BatchFormulaComposition2layer" ]
      ] ) ; #
      fhir:status [ fhir:v "final"] ; #
      fhir:type [
        ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/ICHContextOfUse"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "ich_3.2.p.3.2" ] ;
    fhir:display [ fhir:v "m3.2.p.3.2 batch formula" ]     ] )
      ] ; #
      fhir:date [ fhir:v "2024-08-01T12:34:56.789Z"^^xsd:dateTime] ; #
      fhir:author ( [
    fhir:reference [ fhir:v "urn:uuid:4f3e9af1-306b-4fad-bf04-7881400b266a" ]
      ] ) ; #
      fhir:title [ fhir:v "Batch formula example two layer tablet"] ; #
      fhir:section ( [
    fhir:title [ fhir:v "Batch Formula" ] ;
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/ICHContextOfUse"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "ich_3.2.p.3.2" ] ;
    fhir:display [ fhir:v "m3.2.p.3.2 batch formula" ]       ] )     ] ;
        ( fhir:entry [
    fhir:reference [ fhir:v "urn:uuid:f0f3ff35-5cfa-6617-b8f1-b8167957f53c" ]     ] )
      ] ) . #

    <urn:uuid:4f3e9af1-306b-4fad-bf04-7881400b266a> a fhir:Organization ;
      fhir:id [ fhir:v "4f3e9af1-306b-4fad-bf04-7881400b266a"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_4f3e9af1-306b-4fad-bf04-7881400b266a\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization 4f3e9af1-306b-4fad-bf04-7881400b266a</b></p><a name=\"4f3e9af1-306b-4fad-bf04-7881400b266a\"> </a><a name=\"hc4f3e9af1-306b-4fad-bf04-7881400b266a\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cmc-organization.html\">Basic Organization</a></p></div><p><b>identifier</b>: DUNS/143265222</p><p><b>name</b>: Wunderwerke</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>Wunderwerke, 123 Scenic Road, CT, Bridgeport, USA 65478</td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134003" ] ;
    fhir:display [ fhir:v "DUNS" ]       ] )     ] ;
    fhir:system [ fhir:v "urn:oid:1.3.6.1.4.1.519.1"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "143265222" ]
      ] ) ; #
      fhir:name [ fhir:v "Wunderwerke"] ; #
      fhir:contact ( [
    fhir:address [
    fhir:type [ fhir:v "postal" ] ;
    fhir:text [ fhir:v "Wunderwerke, 123 Scenic Road, CT, Bridgeport, USA 65478" ] ;
          ( fhir:line [ fhir:v "123 Scenic Road" ] ) ;
    fhir:city [ fhir:v "Bridgeport" ] ;
    fhir:state [ fhir:v "CT" ] ;
    fhir:postalCode [ fhir:v "65478" ] ;
    fhir:country [ fhir:v "USA" ]     ]
      ] ) . #

    <urn:uuid:b69435a0-45c6-4d44-9fde-b354e17408d7> a fhir:Organization ;
      fhir:id [ fhir:v "b69435a0-45c6-4d44-9fde-b354e17408d7"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_b69435a0-45c6-4d44-9fde-b354e17408d7\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization b69435a0-45c6-4d44-9fde-b354e17408d7</b></p><a name=\"b69435a0-45c6-4d44-9fde-b354e17408d7\"> </a><a name=\"hcb69435a0-45c6-4d44-9fde-b354e17408d7\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cmc-organization.html\">Basic Organization</a></p></div><p><b>identifier</b>: DUNS/143265222</p><p><b>name</b>: Large Life</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>123 Broad Way, New York, NY, United States</td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134003" ] ;
    fhir:display [ fhir:v "DUNS" ]       ] )     ] ;
    fhir:system [ fhir:v "urn:oid:1.3.6.1.4.1.519.1"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "143265222" ]
      ] ) ; #
      fhir:name [ fhir:v "Large Life"] ; #
      fhir:contact ( [
    fhir:address [
    fhir:type [ fhir:v "postal" ] ;
    fhir:text [ fhir:v "123 Broad Way, New York, NY, United States" ] ;
          ( fhir:line [ fhir:v "123 Broad Way" ] ) ;
    fhir:city [ fhir:v "New York" ] ;
    fhir:state [ fhir:v "NY" ] ;
    fhir:postalCode [ fhir:v "10020" ] ;
    fhir:country [ fhir:v "USA" ]     ]
      ] ) . #

    <urn:uuid:f0f3ff35-5cfa-6617-b8f1-b8167957f53c> a fhir:MedicinalProductDefinition ;
      fhir:id [ fhir:v "f0f3ff35-5cfa-6617-b8f1-b8167957f53c"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-batch-formula-product"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-batch-formula-product>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_f0f3ff35-5cfa-6617-b8f1-b8167957f53c\"> </a><p class=\"res-header-id\"><b>Generated Narrative: MedicinalProductDefinition f0f3ff35-5cfa-6617-b8f1-b8167957f53c</b></p><a name=\"f0f3ff35-5cfa-6617-b8f1-b8167957f53c\"> </a><a name=\"hcf0f3ff35-5cfa-6617-b8f1-b8167957f53c\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-batch-formula-product.html\">Batch Formula Drug Product Identification</a></p></div><p><b>identifier</b>: ASPIRIN-ACETAMINOPHEN-Identification</p><p><b>combinedPharmaceuticalDoseForm</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42964}\">TABLET, MULTILAYER</span></p><p><b>route</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C38288}\">ORAL</span></p><p><b>comprisedOf</b>: <a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-8a3e11d9-4323-43c4-be00-8f0ea1837070\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></p><blockquote><p><b>name</b></p><p><b>productName</b>: ASPIRIN 200mg, ACETAMINOPHEN 300mg</p><p><b>type</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C96971}\">Nonproprietary Name</span></p><blockquote><p><b>part</b></p><p><b>part</b>: ASPIRIN</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2 SCI}\">scientific name</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: 200mg</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2 STR}\">ASPIRIN</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: ACETAMINOPHEN</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2 SCI}\">scientific name</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: 300mg</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2 STR}\">ACETAMINOPHEN</span></p></blockquote></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:value [ fhir:v "ASPIRIN-ACETAMINOPHEN-Identification" ]
      ] ) ; #
      fhir:combinedPharmaceuticalDoseForm [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C42964" ] ;
    fhir:display [ fhir:v "TABLET, MULTILAYER" ]     ] )
      ] ; #
      fhir:route ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C38288" ] ;
    fhir:display [ fhir:v "ORAL" ]     ] )
      ] ) ; #
      fhir:comprisedOf ( [
    fhir:reference [ fhir:v "urn:uuid:8a3e11d9-4323-43c4-be00-8f0ea1837070" ]
      ] ) ; #
      fhir:name ( [
    fhir:productName [ fhir:v "ASPIRIN 200mg, ACETAMINOPHEN 300mg" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C96971" ] ;
    fhir:display [ fhir:v "Nonproprietary Name" ]       ] )     ] ;
        ( fhir:part [
    fhir:part [ fhir:v "ASPIRIN" ] ;
    fhir:type [
            ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "SCI" ]         ] )       ]     ] [
    fhir:part [ fhir:v "200mg" ] ;
    fhir:type [
            ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "STR" ]         ] ) ;
    fhir:text [ fhir:v "ASPIRIN" ]       ]     ] [
    fhir:part [ fhir:v "ACETAMINOPHEN" ] ;
    fhir:type [
            ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "SCI" ]         ] )       ]     ] [
    fhir:part [ fhir:v "300mg" ] ;
    fhir:type [
            ( fhir:coding [
    fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "STR" ]         ] ) ;
    fhir:text [ fhir:v "ACETAMINOPHEN" ]       ]     ] )
      ] ) . #

    <urn:uuid:8a3e11d9-4323-43c4-be00-8f0ea1837070> a fhir:ManufacturedItemDefinition ;
      fhir:id [ fhir:v "8a3e11d9-4323-43c4-be00-8f0ea1837070"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-product-batch-formula"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-product-batch-formula>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "extensions" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ManufacturedItemDefinition_8a3e11d9-4323-43c4-be00-8f0ea1837070\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ManufacturedItemDefinition 8a3e11d9-4323-43c4-be00-8f0ea1837070</b></p><a name=\"8a3e11d9-4323-43c4-be00-8f0ea1837070\"> </a><a name=\"hc8a3e11d9-4323-43c4-be00-8f0ea1837070\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-product-batch-formula.html\">Drug Product Batch Formula</a></p></div><p><b>identifier</b>: ASPIRIN-ACETAMINOPHEN</p><p><b>status</b>: Active</p><p><b>name</b>: ASPIRIN 200mg, ACETAMINOPHEN 300mg 2000 tablets</p><p><b>manufacturedDoseForm</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C154605}\">Tablet</span></p><p><b>manufacturer</b>: <a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-b69435a0-45c6-4d44-9fde-b354e17408d7\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></p><blockquote><p><b>property</b></p><p><b>type</b>: <span title=\"Codes:\">Batch Quantity</span></p><p><b>value</b>: 2000 tablets<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code{tbl} = '{tbl}')</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: <span title=\"Codes:\">Batch Utilization</span></p><p><b>value</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C133991}\">Development</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: <span title=\"Codes:\">Batch Formula Additional Information</span></p><p><b>value</b>: </p><div><p>Makes 2000 tablets equivalent to 2.402 kilograms, accounting for losses from evaporation</p>\n</div></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C66831}\">Layer</span></p><p><b>amount</b>: 925.97 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 38.55 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><blockquote><p><b>constituent</b></p><p><b>amount</b>: 400 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 43.1 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203881}\">Purple Layer</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-d4713a90-38d1-49e5-a977-78c63e518562\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 524.01 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 56.59 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203883}\">Purple Layer</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-9973ba9a-b257-425a-8fb9-6dcfe379ca08\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 203.71 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 22 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203882}\">Purple Layer</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-4e394a0c-4b25-492e-aac7-0faf121ffc4f\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><blockquote><p><b>Overage Extension</b></p><ul><li>proportionDecimal: 0.02</li><li>justification: </li></ul></blockquote><div><p>Evaporation</p>\n</div><p><b>amount</b>: 311.68 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 33 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203882}\">Purple Layer</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-95648837-ec81-42d9-970c-eac390f2f604\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Product Part Identifier</span></td><td><span title=\"Codes:\">Purple Layer</span></td></tr></table></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C66831}\">Layer</span></p><p><b>amount</b>: 1476.03 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 61.45 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><blockquote><p><b>constituent</b></p><p><b>amount</b>: 600.01 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 40.65 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203881}\">Example1Drug_LayerB</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-fbd464cc-2511-4a3a-b058-3cec4fffd14f\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 876.02 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 59.35 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203883}\">Example1Drug_LayerB</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-9973ba9a-b257-425a-8fb9-6dcfe379ca08\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 369.01 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 25 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><p><b>location</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203882}\">Example1Drug_LayerB</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-95648837-ec81-42d9-970c-eac390f2f604\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table></blockquote><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Product Part Identifier</span></td><td><span title=\"Codes:\">Example1Drug_LayerB</span></td></tr></table></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:value [ fhir:v "ASPIRIN-ACETAMINOPHEN" ]
      ] ) ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:name [ fhir:v "ASPIRIN 200mg, ACETAMINOPHEN 300mg 2000 tablets"] ; #
      fhir:manufacturedDoseForm [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C154605" ] ;
    fhir:display [ fhir:v "Tablet" ]     ] )
      ] ; #
      fhir:manufacturer ( [
    fhir:reference [ fhir:v "urn:uuid:b69435a0-45c6-4d44-9fde-b354e17408d7" ]
      ] ) ; #
      fhir:property ( [
    fhir:type [
    fhir:text [ fhir:v "Batch Quantity" ]     ] ;
    fhir:value [
    a fhir:Quantity ;
    fhir:value [ fhir:v "2000"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "tablets" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "{tbl}" ]     ]
      ] [
    fhir:type [
    fhir:text [ fhir:v "Batch Utilization" ]     ] ;
    fhir:value [
    a fhir:CodeableConcept ;
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C133991" ] ;
    fhir:display [ fhir:v "Development" ]       ] )     ]
      ] [
    fhir:type [
    fhir:text [ fhir:v "Batch Formula Additional Information" ]     ] ;
    fhir:value [
    a fhir:markdown ;
    fhir:v "Makes 2000 tablets equivalent to 2.402 kilograms, accounting for losses from evaporation"     ]
      ] ) ; #
      fhir:component ( [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C66831" ] ;
    fhir:display [ fhir:v "Layer" ]       ] )     ] ;
        ( fhir:amount [
    fhir:value [ fhir:v 925.97 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]     ] [
    fhir:value [ fhir:v 38.55 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]     ] ) ;
        ( fhir:constituent [
          ( fhir:amount [
    fhir:value [ fhir:v "400"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v 43.1 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203881" ] ;
    fhir:display [ fhir:v "Active core/granulate" ]         ] ) ;
    fhir:text [ fhir:v "Purple Layer" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:d4713a90-38d1-49e5-a977-78c63e518562" ]         ]       ] )     ] [
          ( fhir:amount [
    fhir:value [ fhir:v 524.01 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v 56.59 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203883" ] ;
    fhir:display [ fhir:v "Intragranular" ]         ] ) ;
    fhir:text [ fhir:v "Purple Layer" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:9973ba9a-b257-425a-8fb9-6dcfe379ca08" ]         ]       ] )     ] [
          ( fhir:amount [
    fhir:value [ fhir:v 203.71 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v "22"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203882" ] ;
    fhir:display [ fhir:v "Extragranular" ]         ] ) ;
    fhir:text [ fhir:v "Purple Layer" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:4e394a0c-4b25-492e-aac7-0faf121ffc4f" ]         ]       ] )     ] [
          ( fhir:extension [
            ( fhir:extension [
    fhir:url [ fhir:v "proportionDecimal"^^xsd:anyURI ] ;
    fhir:value [
    a fhir:decimal ;
    fhir:v 0.02           ]         ] [
    fhir:url [ fhir:v "justification"^^xsd:anyURI ] ;
    fhir:value [
    a fhir:markdown ;
    fhir:v "Evaporation"           ]         ] ) ;
    fhir:url [ fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pq-overage-extension"^^xsd:anyURI ]       ] ) ;
          ( fhir:amount [
    fhir:value [ fhir:v 311.68 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v "33"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203882" ] ;
    fhir:display [ fhir:v "Extragranular" ]         ] ) ;
    fhir:text [ fhir:v "Purple Layer" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:95648837-ec81-42d9-970c-eac390f2f604" ]         ]       ] )     ] ) ;
        ( fhir:property [
    fhir:type [
    fhir:text [ fhir:v "Product Part Identifier" ]       ] ;
    fhir:value [
    a fhir:CodeableConcept ;
    fhir:text [ fhir:v "Purple Layer" ]       ]     ] )
      ] [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C66831" ] ;
    fhir:display [ fhir:v "Layer" ]       ] )     ] ;
        ( fhir:amount [
    fhir:value [ fhir:v 1476.03 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]     ] [
    fhir:value [ fhir:v 61.45 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]     ] ) ;
        ( fhir:constituent [
          ( fhir:amount [
    fhir:value [ fhir:v 600.01 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v 40.65 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203881" ] ;
    fhir:display [ fhir:v "Active core/granulate" ]         ] ) ;
    fhir:text [ fhir:v "Example1Drug_LayerB" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:fbd464cc-2511-4a3a-b058-3cec4fffd14f" ]         ]       ] )     ] [
          ( fhir:amount [
    fhir:value [ fhir:v 876.02 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v 59.35 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203883" ] ;
    fhir:display [ fhir:v "Intragranular" ]         ] ) ;
    fhir:text [ fhir:v "Example1Drug_LayerB" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:9973ba9a-b257-425a-8fb9-6dcfe379ca08" ]         ]       ] )     ] [
          ( fhir:amount [
    fhir:value [ fhir:v 369.01 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ] [
    fhir:value [ fhir:v "25"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ] ) ;
          ( fhir:location [
            ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203882" ] ;
    fhir:display [ fhir:v "Extragranular" ]         ] ) ;
    fhir:text [ fhir:v "Example1Drug_LayerB" ]       ] ) ;
          ( fhir:hasIngredient [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:95648837-ec81-42d9-970c-eac390f2f604" ]         ]       ] )     ] ) ;
        ( fhir:property [
    fhir:type [
    fhir:text [ fhir:v "Product Part Identifier" ]       ] ;
    fhir:value [
    a fhir:CodeableConcept ;
    fhir:text [ fhir:v "Example1Drug_LayerB" ]       ]     ] )
      ] ) . #

    <urn:uuid:d4713a90-38d1-49e5-a977-78c63e518562> a fhir:Ingredient ;
      fhir:id [ fhir:v "d4713a90-38d1-49e5-a977-78c63e518562"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_d4713a90-38d1-49e5-a977-78c63e518562\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient d4713a90-38d1-49e5-a977-78c63e518562</b></p><a name=\"d4713a90-38d1-49e5-a977-78c63e518562\"> </a><a name=\"hcd4713a90-38d1-49e5-a977-78c63e518562\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: Asprin - Ingredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C82533}\">Active Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-cbb54715-3928-4e3f-9abe-32914f694957\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 400 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 10.4 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier [
    fhir:value [ fhir:v "Asprin - Ingredient" ]
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C82533" ] ;
    fhir:display [ fhir:v "Active Ingredient" ]     ] )
      ] ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:cbb54715-3928-4e3f-9abe-32914f694957" ]       ]     ] ;
        ( fhir:strength [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "400"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 10.4 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ] )
      ] . #

    <urn:uuid:fbd464cc-2511-4a3a-b058-3cec4fffd14f> a fhir:Ingredient ;
      fhir:id [ fhir:v "fbd464cc-2511-4a3a-b058-3cec4fffd14f"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_fbd464cc-2511-4a3a-b058-3cec4fffd14f\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient fbd464cc-2511-4a3a-b058-3cec4fffd14f</b></p><a name=\"fbd464cc-2511-4a3a-b058-3cec4fffd14f\"> </a><a name=\"hcfbd464cc-2511-4a3a-b058-3cec4fffd14f\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: AcetaminophenIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C82533}\">Active Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-ca1ff85f-3f05-46be-8cc4-30b076d88c13\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 600 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 25 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier [
    fhir:value [ fhir:v "AcetaminophenIngredient" ]
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C82533" ] ;
    fhir:display [ fhir:v "Active Ingredient" ]     ] )
      ] ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:ca1ff85f-3f05-46be-8cc4-30b076d88c13" ]       ]     ] ;
        ( fhir:strength [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "600"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v "25"^^xsd:decimal ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ] )
      ] . #

    <urn:uuid:9973ba9a-b257-425a-8fb9-6dcfe379ca08> a fhir:Ingredient ;
      fhir:id [ fhir:v "9973ba9a-b257-425a-8fb9-6dcfe379ca08"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_9973ba9a-b257-425a-8fb9-6dcfe379ca08\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 9973ba9a-b257-425a-8fb9-6dcfe379ca08</b></p><a name=\"9973ba9a-b257-425a-8fb9-6dcfe379ca08\"> </a><a name=\"hc9973ba9a-b257-425a-8fb9-6dcfe379ca08\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: MaizeStarchIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-99f4a24f-880f-45f1-8364-8e4e03977b2e\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 1400.03 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 58.28 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier [
    fhir:value [ fhir:v "MaizeStarchIngredient" ]
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C42637" ] ;
    fhir:display [ fhir:v "Inactive Ingredient" ]     ] )
      ] ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:99f4a24f-880f-45f1-8364-8e4e03977b2e" ]       ]     ] ;
        ( fhir:strength [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 1400.03 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 58.28 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ] )
      ] . #

    <urn:uuid:4e394a0c-4b25-492e-aac7-0faf121ffc4f> a fhir:Ingredient ;
      fhir:id [ fhir:v "4e394a0c-4b25-492e-aac7-0faf121ffc4f"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_4e394a0c-4b25-492e-aac7-0faf121ffc4f\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 4e394a0c-4b25-492e-aac7-0faf121ffc4f</b></p><a name=\"4e394a0c-4b25-492e-aac7-0faf121ffc4f\"> </a><a name=\"hc4e394a0c-4b25-492e-aac7-0faf121ffc4f\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: GrapeskinIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-a4624559-6c4f-4e90-996d-bc3bf2f5a3f4\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 203.71 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 8.48 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier [
    fhir:value [ fhir:v "GrapeskinIngredient" ]
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C42637" ] ;
    fhir:display [ fhir:v "Inactive Ingredient" ]     ] )
      ] ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:a4624559-6c4f-4e90-996d-bc3bf2f5a3f4" ]       ]     ] ;
        ( fhir:strength [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 203.71 ] ;
    fhir:unit [ fhir:v "gram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "g" ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 8.48 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ] )
      ] . #

    <urn:uuid:95648837-ec81-42d9-970c-eac390f2f604> a fhir:Ingredient ;
      fhir:id [ fhir:v "95648837-ec81-42d9-970c-eac390f2f604"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_95648837-ec81-42d9-970c-eac390f2f604\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 95648837-ec81-42d9-970c-eac390f2f604</b></p><a name=\"95648837-ec81-42d9-970c-eac390f2f604\"> </a><a name=\"hc95648837-ec81-42d9-970c-eac390f2f604\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: WaterBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-254742fb-7b5b-49f5-b4af-e0d14d81f2f6\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 50.75 kilogram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codekg = 'kg')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 95.3572 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier [
    fhir:value [ fhir:v "WaterBFIngredient" ]
      ] ; #
      fhir:status [ fhir:v "active"] ; #
      fhir:role [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C42637" ] ;
    fhir:display [ fhir:v "Inactive Ingredient" ]     ] )
      ] ; #
      fhir:substance [
    fhir:code [
    fhir:reference [
    fhir:reference [ fhir:v "urn:uuid:254742fb-7b5b-49f5-b4af-e0d14d81f2f6" ]       ]     ] ;
        ( fhir:strength [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 50.75 ] ;
    fhir:unit [ fhir:v "kilogram" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "kg" ]       ]     ] [
    fhir:concentration [
    a fhir:Quantity ;
    fhir:value [ fhir:v 95.3572 ] ;
    fhir:unit [ fhir:v "percent" ] ;
    fhir:system [ fhir:v "http://unitsofmeasure.org"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "%" ]       ]     ] )
      ] . #

    <urn:uuid:cbb54715-3928-4e3f-9abe-32914f694957> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "cbb54715-3928-4e3f-9abe-32914f694957"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-routine-drug-substance"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-routine-drug-substance>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_cbb54715-3928-4e3f-9abe-32914f694957\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition cbb54715-3928-4e3f-9abe-32914f694957</b></p><a name=\"cbb54715-3928-4e3f-9abe-32914f694957\"> </a><a name=\"hccbb54715-3928-4e3f-9abe-32914f694957\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-routine-drug-substance.html\">Drug Substance Handle</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><p><b>manufacturer</b>: <a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-e165f057-5eed-4e64-8328-4438fc88fb1b\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov R16CO5Y76E}\">R16CO5Y76E</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>ASPIRIN</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:classification ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C48807" ] ;
    fhir:display [ fhir:v "Chemical" ]     ] )
      ] ) ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134006" ] ;
    fhir:display [ fhir:v "USP-NF" ]     ] )
      ] ) ; #
      fhir:manufacturer ( [
    fhir:reference [ fhir:v "urn:uuid:e165f057-5eed-4e64-8328-4438fc88fb1b" ]
      ] ) ; #
      fhir:code ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://fdasis.nlm.nih.gov"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "R16CO5Y76E" ]       ] )     ]
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "ASPIRIN" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203355" ] ;
    fhir:display [ fhir:v "GSRS Preferred Term" ]       ] )     ] ;
    fhir:preferred [ fhir:v true ]
      ] ) . #

    <urn:uuid:ca1ff85f-3f05-46be-8cc4-30b076d88c13> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "ca1ff85f-3f05-46be-8cc4-30b076d88c13"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-routine-drug-substance"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-routine-drug-substance>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_ca1ff85f-3f05-46be-8cc4-30b076d88c13\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition ca1ff85f-3f05-46be-8cc4-30b076d88c13</b></p><a name=\"ca1ff85f-3f05-46be-8cc4-30b076d88c13\"> </a><a name=\"hcca1ff85f-3f05-46be-8cc4-30b076d88c13\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-routine-drug-substance.html\">Drug Substance Handle</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><p><b>manufacturer</b>: <a href=\"Bundle-BatchFormulaBundle2Layer.html#urn-uuid-4b565cf3-5353-48af-8cd6-5ccf4e9fd579\">Bundle: identifier = UUID:49d3b79e-b436-a242-93ba-b706b4364ab2; type = document; timestamp = 2024-08-29 12:34:56+0000</a></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov 362O9ITL9D}\">362O9ITL9D</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>ACETAMINOPHEN</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:classification ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C48807" ] ;
    fhir:display [ fhir:v "Chemical" ]     ] )
      ] ) ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134006" ] ;
    fhir:display [ fhir:v "USP-NF" ]     ] )
      ] ) ; #
      fhir:manufacturer ( [
    fhir:reference [ fhir:v "urn:uuid:4b565cf3-5353-48af-8cd6-5ccf4e9fd579" ]
      ] ) ; #
      fhir:code ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://fdasis.nlm.nih.gov"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "362O9ITL9D" ]       ] )     ]
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "ACETAMINOPHEN" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203355" ] ;
    fhir:display [ fhir:v "GSRS Preferred Term" ]       ] )     ] ;
    fhir:preferred [ fhir:v true ]
      ] ) . #

    <urn:uuid:99f4a24f-880f-45f1-8364-8e4e03977b2e> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "99f4a24f-880f-45f1-8364-8e4e03977b2e"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_99f4a24f-880f-45f1-8364-8e4e03977b2e\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition 99f4a24f-880f-45f1-8364-8e4e03977b2e</b></p><a name=\"99f4a24f-880f-45f1-8364-8e4e03977b2e\"> </a><a name=\"hc99f4a24f-880f-45f1-8364-8e4e03977b2e\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C45305}\">Mixture</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134009}\">Company Standard</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov O8232NY3SJ}\">O8232NY3SJ</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>STARCH, CORN</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:classification ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C45305" ] ;
    fhir:display [ fhir:v "Mixture" ]     ] )
      ] ) ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134009" ] ;
    fhir:display [ fhir:v "Company Standard" ]     ] )
      ] ) ; #
      fhir:code ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://fdasis.nlm.nih.gov"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "O8232NY3SJ" ]       ] )     ]
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "STARCH, CORN" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203355" ] ;
    fhir:display [ fhir:v "GSRS Preferred Term" ]       ] )     ] ;
    fhir:preferred [ fhir:v true ]
      ] ) ; #
      fhir:sourceMaterial [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C48807" ] ;
    fhir:display [ fhir:v "Chemical" ]       ] )     ]
      ] . #

    <urn:uuid:a4624559-6c4f-4e90-996d-bc3bf2f5a3f4> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "a4624559-6c4f-4e90-996d-bc3bf2f5a3f4"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_a4624559-6c4f-4e90-996d-bc3bf2f5a3f4\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition a4624559-6c4f-4e90-996d-bc3bf2f5a3f4</b></p><a name=\"a4624559-6c4f-4e90-996d-bc3bf2f5a3f4\"> </a><a name=\"hca4624559-6c4f-4e90-996d-bc3bf2f5a3f4\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C45305}\">Mixture</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C176793}\">BP</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov 3GOV20705G}\">3GOV20705G</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>WINE GRAPE</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Genus</b></td><td><b>Species</b></td><td><b>Part</b></td><td><b>CountryOfOrigin</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C14258}\">Plant</span></td><td><span title=\"Codes:\">vitis</span></td><td><span title=\"Codes:\">vinifera</span></td><td><span title=\"Codes:\">fruit skin</span></td><td><span title=\"Codes:{urn:iso:std:iso:3166 ITA}\">Italy</span></td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:classification ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C45305" ] ;
    fhir:display [ fhir:v "Mixture" ]     ] )
      ] ) ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C176793" ] ;
    fhir:display [ fhir:v "BP" ]     ] )
      ] ) ; #
      fhir:code ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://fdasis.nlm.nih.gov"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "3GOV20705G" ]       ] )     ]
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "WINE GRAPE" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203355" ] ;
    fhir:display [ fhir:v "GSRS Preferred Term" ]       ] )     ] ;
    fhir:preferred [ fhir:v true ]
      ] ) ; #
      fhir:sourceMaterial [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C14258" ] ;
    fhir:display [ fhir:v "Plant" ]       ] )     ] ;
    fhir:genus [
    fhir:text [ fhir:v "vitis" ]     ] ;
    fhir:species [
    fhir:text [ fhir:v "vinifera" ]     ] ;
    fhir:part [
    fhir:text [ fhir:v "fruit skin" ]     ] ;
        ( fhir:countryOfOrigin [
          ( fhir:coding [
    fhir:system [ fhir:v "urn:iso:std:iso:3166"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "ITA" ] ;
    fhir:display [ fhir:v "Italy" ]       ] )     ] )
      ] . #

    <urn:uuid:254742fb-7b5b-49f5-b4af-e0d14d81f2f6> a fhir:SubstanceDefinition ;
      fhir:id [ fhir:v "254742fb-7b5b-49f5-b4af-e0d14d81f2f6"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_254742fb-7b5b-49f5-b4af-e0d14d81f2f6\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition 254742fb-7b5b-49f5-b4af-e0d14d81f2f6</b></p><a name=\"254742fb-7b5b-49f5-b4af-e0d14d81f2f6\"> </a><a name=\"hc254742fb-7b5b-49f5-b4af-e0d14d81f2f6\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov 059QF0KO0R}\">059QF0KO0R</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>WATER</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:classification ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C48807" ] ;
    fhir:display [ fhir:v "Chemical" ]     ] )
      ] ) ; #
      fhir:grade ( [
        ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134006" ] ;
    fhir:display [ fhir:v "USP-NF" ]     ] )
      ] ) ; #
      fhir:code ( [
    fhir:code [
          ( fhir:coding [
    fhir:system [ fhir:v "http://fdasis.nlm.nih.gov"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "059QF0KO0R" ]       ] )     ]
      ] ) ; #
      fhir:name ( [
    fhir:name [ fhir:v "WATER" ] ;
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C203355" ] ;
    fhir:display [ fhir:v "GSRS Preferred Term" ]       ] )     ] ;
    fhir:preferred [ fhir:v true ]
      ] ) ; #
      fhir:sourceMaterial [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C48807" ] ;
    fhir:display [ fhir:v "Chemical" ]       ] )     ]
      ] . #

    <urn:uuid:4b565cf3-5353-48af-8cd6-5ccf4e9fd579> a fhir:Organization ;
      fhir:id [ fhir:v "4b565cf3-5353-48af-8cd6-5ccf4e9fd579"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_4b565cf3-5353-48af-8cd6-5ccf4e9fd579\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization 4b565cf3-5353-48af-8cd6-5ccf4e9fd579</b></p><a name=\"4b565cf3-5353-48af-8cd6-5ccf4e9fd579\"> </a><a name=\"hc4b565cf3-5353-48af-8cd6-5ccf4e9fd579\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cmc-organization.html\">Basic Organization</a></p></div><p><b>identifier</b>: DUNS/783452221, FEI/6913973</p><p><b>name</b>: Manufacturing Site (J. Jones Research)</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>Manufacturing Site (J. Jones Research), 444 Grant Street, Bedford, NY, United States</td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134003" ] ;
    fhir:display [ fhir:v "DUNS" ]       ] )     ] ;
    fhir:system [ fhir:v "urn:oid:1.3.6.1.4.1.519.1"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "783452221" ]
      ] [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134004" ] ;
    fhir:display [ fhir:v "FEI" ]       ] )     ] ;
    fhir:system [ fhir:v "urn:oid:2.16.840.1.113883.4.82"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "6913973" ]
      ] ) ; #
      fhir:name [ fhir:v "Manufacturing Site (J. Jones Research)"] ; #
      fhir:contact ( [
    fhir:address [
    fhir:type [ fhir:v "postal" ] ;
    fhir:text [ fhir:v "Manufacturing Site (J. Jones Research), 444 Grant Street, Bedford, NY, United States" ] ;
          ( fhir:line [ fhir:v "444 Grant Street" ] ) ;
    fhir:city [ fhir:v "Bedford" ] ;
    fhir:state [ fhir:v "NY" ] ;
    fhir:postalCode [ fhir:v "15600" ] ;
    fhir:country [ fhir:v "USA" ]     ]
      ] ) . #

    <urn:uuid:e165f057-5eed-4e64-8328-4438fc88fb1b> a fhir:Organization ;
      fhir:id [ fhir:v "e165f057-5eed-4e64-8328-4438fc88fb1b"] ; #
      fhir:meta [
        ( fhir:profile [
    fhir:v "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization"^^xsd:anyURI ;
    fhir:link <http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization>     ] )
      ] ; #
      fhir:text [
    fhir:status [ fhir:v "generated" ] ;
    fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_e165f057-5eed-4e64-8328-4438fc88fb1b\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization e165f057-5eed-4e64-8328-4438fc88fb1b</b></p><a name=\"e165f057-5eed-4e64-8328-4438fc88fb1b\"> </a><a name=\"hce165f057-5eed-4e64-8328-4438fc88fb1b\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cmc-organization.html\">Basic Organization</a></p></div><p><b>identifier</b>: DUNS/143265222</p><p><b>name</b>: Vandechemie</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>Vandechemie, Ruzettelaan 39234, Blankenberge, 8370, Belgium</td></tr></table></div>"^^rdf:XMLLiteral
      ] ; #
      fhir:identifier ( [
    fhir:type [
          ( fhir:coding [
    fhir:system [ fhir:v "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl"^^xsd:anyURI ] ;
    fhir:code [ fhir:v "C134003" ] ;
    fhir:display [ fhir:v "DUNS" ]       ] )     ] ;
    fhir:system [ fhir:v "urn:oid:1.3.6.1.4.1.519.1"^^xsd:anyURI ] ;
    fhir:value [ fhir:v "143265222" ]
      ] ) ; #
      fhir:name [ fhir:v "Vandechemie"] ; #
      fhir:contact ( [
    fhir:address [
    fhir:type [ fhir:v "postal" ] ;
    fhir:text [ fhir:v "Vandechemie, Ruzettelaan 39234, Blankenberge, 8370, Belgium" ] ;
          ( fhir:line [ fhir:v "Ruzettelaan 39234" ] ) ;
    fhir:city [ fhir:v "Blankenberge" ] ;
    fhir:postalCode [ fhir:v "8370" ] ;
    fhir:country [ fhir:v "BEL" ]     ]
      ] ) . #