Pharmaceutical Quality - Chemistry, Manufacturing and Controls (PQ-CMC) Submissions to FDA
2.0.0 - STU2

Pharmaceutical Quality - Chemistry, Manufacturing and Controls (PQ-CMC) Submissions to FDA, published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 2.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/FHIR-us-pq-cmc-fda/ and changes regularly. See the Directory of published versions

## ValueSet: Drug Route Of Administration Terminology

Official URL: http://hl7.org/fhir/us/pq-cmc-fda/ValueSet/spl-drug-route-of-administration-terminology | Version: 2.0.0
Standards status: Trial-use | Maturity Level: 2 | Computable Name: SplDrugRouteofAdministrationTerminology
Other Identifiers: OID:2.16.840.1.113883.4.642.40.36.48.32

Terminology used for representation of the information on pharmaceutical product route of administration in the framework of the Structured Product Labeling documents.

References

- Batch Formula Drug Product Identification
- Drug Product Description
- Drug Product Handle
- Drug Product Impurities

### Logical Definition (CLD)

- Include these codes as defined in `http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl`

  Code | Display
  C132737 | Intracanalicular
  C28161 | INTRAMUSCULAR
  C38192 | AURICULAR (OTIC)
  C38193 | BUCCAL
  C38194 | CONJUNCTIVAL
  C38197 | DENTAL
  C38198 | SOFT TISSUE
  C38200 | HEMODIALYSIS
  C38203 | IONTOPHORESIS
  C38205 | ENDOCERVICAL
  C38206 | ENDOSINUSIAL
  C38207 | INTRATHORACIC
  C38208 | ENDOTRACHEAL
  C38209 | ENTERAL
  C38210 | EPIDURAL
  C38211 | EXTRA-AMNIOTIC
  C38212 | EXTRACORPOREAL
  C38215 | INFILTRATION
  C38216 | RESPIRATORY (INHALATION)
  C38217 | INTRACORONAL, DENTAL
  C38218 | INTRACORONARY
  C38219 | INTERSTITIAL
  C38220 | INTRA-ABDOMINAL
  C38221 | INTRA-AMNIOTIC
  C38222 | INTRA-ARTERIAL
  C38223 | INTRA-ARTICULAR
  C38224 | INTRABILIARY
  C38225 | INTRABRONCHIAL
  C38226 | INTRABURSAL
  C38227 | INTRACARDIAC
  C38228 | INTRACARTILAGINOUS
  C38229 | INTRACAUDAL
  C38230 | INTRACAVERNOUS
  C38231 | INTRACAVITARY
  C38232 | INTRACEREBRAL
  C38233 | INTRACISTERNAL
  C38234 | INTRACORNEAL
  C38235 | INTRACORPORUS CAVERNOSUM
  C38236 | INTRACRANIAL
  C38238 | INTRADERMAL
  C38239 | INTRADISCAL
  C38240 | INTRADUCTAL
  C38241 | INTRADUODENAL
  C38242 | INTRADURAL
  C38243 | INTRAEPIDERMAL
  C38245 | INTRAESOPHAGEAL
  C38246 | INTRAGASTRIC
  C38247 | INTRAGINGIVAL
  C38248 | INTRAHEPATIC
  C38249 | INTRAILEAL
  C38250 | INTRALESIONAL
  C38251 | INTRALUMINAL
  C38252 | INTRALYMPHATIC
  C38253 | INTRAMEDULLARY
  C38254 | INTRAMENINGEAL
  C38255 | INTRAOCULAR
  C38256 | INTRAOVARIAN
  C38257 | INTRAPERICARDIAL
  C38258 | INTRAPERITONEAL
  C38259 | INTRAPLEURAL
  C38260 | INTRAPROSTATIC
  C38261 | INTRAPULMONARY
  C38262 | INTRASINAL
  C38263 | INTRASPINAL
  C38264 | INTRASYNOVIAL
  C38265 | INTRATENDINOUS
  C38266 | INTRATESTICULAR
  C38267 | INTRATHECAL
  C38268 | INTRATUBULAR
  C38269 | INTRATUMOR
  C38270 | INTRATYMPANIC
  C38271 | URETHRAL
  C38272 | INTRAUTERINE
  C38273 | INTRAVASCULAR
  C38274 | INTRAVENOUS BOLUS
  C38276 | INTRAVENOUS
  C38277 | INTRAVENTRICULAR
  C38278 | INTRAVESICAL
  C38279 | INTRAVENOUS DRIP
  C38280 | INTRAVITREAL
  C38281 | IRRIGATION
  C38282 | LARYNGEAL
  C38283 | TRANSMUCOSAL
  C38284 | NASAL
  C38285 | NASOGASTRIC
  C38286 | OCCLUSIVE DRESSING TECHNIQUE
  C38287 | OPHTHALMIC
  C38288 | ORAL
  C38289 | OROPHARYNGEAL
  C38290 | OTHER
  C38291 | PARENTERAL
  C38292 | PERIARTICULAR
  C38293 | PERINEURAL
  C38294 | PERIODONTAL
  C38295 | RECTAL
  C38296 | RETROBULBAR
  C38297 | SUBARACHNOID
  C38298 | SUBCONJUNCTIVAL
  C38299 | SUBCUTANEOUS
  C38300 | SUBLINGUAL
  C38301 | SUBMUCOSAL
  C38304 | TOPICAL
  C38305 | TRANSDERMAL
  C38307 | TRANSPLACENTAL
  C38308 | TRANSTRACHEAL
  C38309 | TRANSTYMPANIC
  C38310 | UNASSIGNED
  C38311 | UNKNOWN
  C38312 | URETERAL
  C38313 | VAGINAL
  C38633 | ELECTRO-OSMOSIS
  C38675 | CUTANEOUS
  C38676 | PERCUTANEOUS
  C38677 | PERIDURAL
  C48623 | NOT APPLICABLE
  C65103 | SUBGINGIVAL
  C79137 | INTRAMAMMARY
  C79138 | INTRALINGUAL
  C79139 | INTRARUMINAL
  C79141 | INTRANODAL
  C79142 | INTRAOMENTUM
  C79143 | SUBRETINAL
  C79144 | INTRAEPICARDIAL
  C79145 | TRANSENDOCARDIAL

### Expansion

Expansion from tx.fhir.org based on supplement PQ-CMC-FDA NCIt Hierarchy Supplement v2.0.0 (CodeSystem)

This value set contains 124 concepts

Code | System | Display (en-US)
C132737 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | Intracanalicular
C28161 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAMUSCULAR
C38192 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | AURICULAR (OTIC)
C38193 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | BUCCAL
C38194 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | CONJUNCTIVAL
C38197 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | DENTAL
C38198 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SOFT TISSUE
C38200 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | HEMODIALYSIS
C38203 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | IONTOPHORESIS
C38205 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | ENDOCERVICAL
C38206 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | ENDOSINUSIAL
C38207 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATHORACIC
C38208 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | ENDOTRACHEAL
C38209 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | ENTERAL
C38210 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | EPIDURAL
C38211 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | EXTRA-AMNIOTIC
C38212 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | EXTRACORPOREAL
C38215 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INFILTRATION
C38216 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | RESPIRATORY (INHALATION)
C38217 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACORONAL, DENTAL
C38218 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACORONARY
C38219 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTERSTITIAL
C38220 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRA-ABDOMINAL
C38221 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRA-AMNIOTIC
C38222 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRA-ARTERIAL
C38223 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRA-ARTICULAR
C38224 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRABILIARY
C38225 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRABRONCHIAL
C38226 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRABURSAL
C38227 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACARDIAC
C38228 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACARTILAGINOUS
C38229 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACAUDAL
C38230 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACAVERNOUS
C38231 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACAVITARY
C38232 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACEREBRAL
C38233 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACISTERNAL
C38234 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACORNEAL
C38235 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACORPORUS CAVERNOSUM
C38236 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRACRANIAL
C38238 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRADERMAL
C38239 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRADISCAL
C38240 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRADUCTAL
C38241 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRADUODENAL
C38242 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRADURAL
C38243 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAEPIDERMAL
C38245 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAESOPHAGEAL
C38246 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAGASTRIC
C38247 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAGINGIVAL
C38248 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAHEPATIC
C38249 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAILEAL
C38250 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRALESIONAL
C38251 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRALUMINAL
C38252 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRALYMPHATIC
C38253 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAMEDULLARY
C38254 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAMENINGEAL
C38255 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAOCULAR
C38256 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAOVARIAN
C38257 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAPERICARDIAL
C38258 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAPERITONEAL
C38259 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAPLEURAL
C38260 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAPROSTATIC
C38261 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAPULMONARY
C38262 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRASINAL
C38263 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRASPINAL
C38264 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRASYNOVIAL
C38265 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATENDINOUS
C38266 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATESTICULAR
C38267 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATHECAL
C38268 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATUBULAR
C38269 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATUMOR
C38270 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRATYMPANIC
C38271 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | URETHRAL
C38272 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAUTERINE
C38273 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVASCULAR
C38274 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVENOUS BOLUS
C38276 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVENOUS
C38277 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVENTRICULAR
C38278 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVESICAL
C38279 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVENOUS DRIP
C38280 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAVITREAL
C38281 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | IRRIGATION
C38282 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | LARYNGEAL
C38283 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TRANSMUCOSAL
C38284 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | NASAL
C38285 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | NASOGASTRIC
C38286 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | OCCLUSIVE DRESSING TECHNIQUE
C38287 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | OPHTHALMIC
C38288 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | ORAL
C38289 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | OROPHARYNGEAL
C38290 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | OTHER
C38291 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | PARENTERAL
C38292 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | PERIARTICULAR
C38293 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | PERINEURAL
C38294 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | PERIODONTAL
C38295 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | RECTAL
C38296 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | RETROBULBAR
C38297 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBARACHNOID
C38298 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBCONJUNCTIVAL
C38299 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBCUTANEOUS
C38300 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBLINGUAL
C38301 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBMUCOSAL
C38304 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TOPICAL
C38305 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TRANSDERMAL
C38307 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TRANSPLACENTAL
C38308 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TRANSTRACHEAL
C38309 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TRANSTYMPANIC
C38310 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | UNASSIGNED
C38311 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | UNKNOWN
C38312 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | URETERAL
C38313 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | VAGINAL
C38633 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | ELECTRO-OSMOSIS
C38675 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | CUTANEOUS
C38676 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | PERCUTANEOUS
C38677 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | PERIDURAL
C48623 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | NOT APPLICABLE
C65103 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBGINGIVAL
C79137 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAMAMMARY
C79138 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRALINGUAL
C79139 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRARUMINAL
C79141 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRANODAL
C79142 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAOMENTUM
C79143 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | SUBRETINAL
C79144 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | INTRAEPICARDIAL
C79145 | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl | TRANSENDOCARDIAL

Explanation of the columns that may appear on this page:

Level | A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System | The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code | The code (used as the code in the resource instance)
Display | The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition | An explanation of the meaning of the concept
Comments | Additional notes about how to use the code