Pharmaceutical Quality - Chemistry, Manufacturing and Controls (PQ-CMC) Submissions to FDA
2.0.0 - STU2

Pharmaceutical Quality - Chemistry, Manufacturing and Controls (PQ-CMC) Submissions to FDA, published by HL7 International / Biomedical Research and Regulation. This guide is not an authorized publication; it is the continuous build for version 2.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/HL7/FHIR-us-pq-cmc-fda/ and changes regularly. See the Directory of published versions

## : 3.2.P.3.2 Bundle for liquid - JSON Representation

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      "resourceType" : "Bundle",
      "id" : "BatchFormulaBundle",
      "meta" : {
        "profile" : [
          🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-ectd-document-32p32"
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      "identifier" : {
        "system" : "urn:ietf:rfc:3986",
        "value" : "urn:uuid:a242b79e-b706-49d3-93ba-b4364ab2baa3"
      },
      "type" : "document",
      "timestamp" : "2024-07-01T12:34:56.789Z",
      "entry" : [
        {
          "fullUrl" : "urn:uuid:0003c00b-bfc2-4775-8b1c-9f99d5cf1f39",
          "resource" : {
            "resourceType" : "Composition",
            "id" : "0003c00b-bfc2-4775-8b1c-9f99d5cf1f39",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/ectd-composition-32p32"
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            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Composition_0003c00b-bfc2-4775-8b1c-9f99d5cf1f39\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Composition 0003c00b-bfc2-4775-8b1c-9f99d5cf1f39</b></p><a name=\"0003c00b-bfc2-4775-8b1c-9f99d5cf1f39\"> </a><a name=\"hc0003c00b-bfc2-4775-8b1c-9f99d5cf1f39\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-ectd-composition-32p32.html\">eCTD Batch Formula</a></p></div><p><b>identifier</b>: BatchFormulaComposition</p><p><b>status</b>: Final</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/ICHContextOfUse ich_3.2.p.3.2}\">m3.2.p.3.2 batch formula</span></p><p><b>date</b>: 2024-07-01 12:34:56+0000</p><p><b>author</b>: <a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-4f3e9af1-306b-4fad-bf04-7881400b266a\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></p><p><b>title</b>: Batch formula example</p></div>"
            },
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              {
                "value" : "BatchFormulaComposition"
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            "status" : "final",
            "type" : {
              "coding" : [
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                  "system" : "http://terminology.hl7.org/CodeSystem/ICHContextOfUse",
                  "code" : "ich_3.2.p.3.2",
                  "display" : "m3.2.p.3.2 batch formula"
                }
              ]
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            "date" : "2024-07-01T12:34:56.789Z",
            "author" : [
              {
                "reference" : "urn:uuid:4f3e9af1-306b-4fad-bf04-7881400b266a"
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            "title" : "Batch formula example",
            "section" : [
              {
                "title" : "Batch Formula",
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/ICHContextOfUse",
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        {
          "fullUrl" : "urn:uuid:4f3e9af1-306b-4fad-bf04-7881400b266a",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "4f3e9af1-306b-4fad-bf04-7881400b266a",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization"
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            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_4f3e9af1-306b-4fad-bf04-7881400b266a\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization 4f3e9af1-306b-4fad-bf04-7881400b266a</b></p><a name=\"4f3e9af1-306b-4fad-bf04-7881400b266a\"> </a><a name=\"hc4f3e9af1-306b-4fad-bf04-7881400b266a\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cmc-organization.html\">Basic Organization</a></p></div><p><b>identifier</b>: DUNS/143265222</p><p><b>name</b>: Wunderwerke</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>Wunderwerke, 123 Scenic Road, CT, Bridgeport, USA 65478</td></tr></table></div>"
            },
            "identifier" : [
              {
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C134003",
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                },
                "system" : "urn:oid:1.3.6.1.4.1.519.1",
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            "name" : "Wunderwerke",
            "contact" : [
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                "address" : {
                  "type" : "postal",
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                    "123 Scenic Road"
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                  "city" : "Bridgeport",
                  "state" : "CT",
                  "postalCode" : "65478",
                  "country" : "USA"
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        },
        {
          "fullUrl" : "urn:uuid:e875ef93-a730-4c44-bead-53663ae7f501",
          "resource" : {
            "resourceType" : "Organization",
            "id" : "e875ef93-a730-4c44-bead-53663ae7f501",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/cmc-organization"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Organization_e875ef93-a730-4c44-bead-53663ae7f501\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Organization e875ef93-a730-4c44-bead-53663ae7f501</b></p><a name=\"e875ef93-a730-4c44-bead-53663ae7f501\"> </a><a name=\"hce875ef93-a730-4c44-bead-53663ae7f501\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cmc-organization.html\">Basic Organization</a></p></div><p><b>identifier</b>: DUNS/147275722, FEI/6981397</p><p><b>name</b>: East-West Manufacturing</p><h3>Contacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Address</b></td></tr><tr><td style=\"display: none\">*</td><td>East-West Manufacturing, 100 Stillwater Avenue, Building #2, Bangor, ME, United States</td></tr></table></div>"
            },
            "identifier" : [
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                "type" : {
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                      "code" : "C134003",
                      "display" : "DUNS"
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                  ]
                },
                "system" : "urn:oid:1.3.6.1.4.1.519.1",
                "value" : "147275722"
              },
              {
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C134004",
                      "display" : "FEI"
                    }
                  ]
                },
                "system" : "urn:oid:2.16.840.1.113883.4.82",
                "value" : "6981397"
              }
            ],
            "name" : "East-West Manufacturing",
            "contact" : [
              {
                "address" : {
                  "type" : "postal",
                  "text" : "East-West Manufacturing, 100 Stillwater Avenue, Building #2, Bangor, ME, United States",
                  "line" : [
                    "100 Stillwater Avenue",
                    "Building #2"
                  ],
                  "city" : "Bangor",
                  "state" : "ME",
                  "postalCode" : "04401",
                  "country" : "USA"
                }
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        },
        {
          "fullUrl" : "urn:uuid:d0d2df25-5cfa-4417-b8d1-b8147957f53c",
          "resource" : {
            "resourceType" : "MedicinalProductDefinition",
            "id" : "d0d2df25-5cfa-4417-b8d1-b8147957f53c",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-batch-formula-product"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"MedicinalProductDefinition_d0d2df25-5cfa-4417-b8d1-b8147957f53c\"> </a><p class=\"res-header-id\"><b>Generated Narrative: MedicinalProductDefinition d0d2df25-5cfa-4417-b8d1-b8147957f53c</b></p><a name=\"d0d2df25-5cfa-4417-b8d1-b8147957f53c\"> </a><a name=\"hcd0d2df25-5cfa-4417-b8d1-b8147957f53c\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-batch-formula-product.html\">Batch Formula Drug Product Identification</a></p></div><p><b>identifier</b>: Oxazepam-Propranolol-BatchFormula-Identification</p><p><b>combinedPharmaceuticalDoseForm</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42953}\">LIQUID</span></p><p><b>route</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C38288}\">ORAL</span></p><p><b>comprisedOf</b>: <a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-249ef22b-d521-4304-a388-6b9035f97b22\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></p><blockquote><p><b>name</b></p><p><b>productName</b>: ATOMOXETINE HYDROCHLORIDE 1mg</p><p><b>type</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C96971}\">Nonproprietary Name</span></p><blockquote><p><b>part</b></p><p><b>part</b>: ATOMOXETINE HYDROCHLORIDE</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2 SCI}\">scientific name</span></p></blockquote><blockquote><p><b>part</b></p><p><b>part</b>: 1mg</p><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2 STR}\">ATOMOXETINE HYDROCHLORIDE</span></p></blockquote></blockquote></div>"
            },
            "identifier" : [
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                "value" : "Oxazepam-Propranolol-BatchFormula-Identification"
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            ],
            "combinedPharmaceuticalDoseForm" : {
              "coding" : [
                {
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                  "code" : "C42953",
                  "display" : "LIQUID"
                }
              ]
            },
            "route" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C38288",
                    "display" : "ORAL"
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                ]
              }
            ],
            "comprisedOf" : [
              {
                "reference" : "urn:uuid:249ef22b-d521-4304-a388-6b9035f97b22"
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            ],
            "name" : [
              {
                "productName" : "ATOMOXETINE HYDROCHLORIDE 1mg",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C96971",
                      "display" : "Nonproprietary Name"
                    }
                  ]
                },
                "part" : [
                  {
                    "part" : "ATOMOXETINE HYDROCHLORIDE",
                    "type" : {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2",
                          "code" : "SCI"
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                    }
                  },
                  {
                    "part" : "1mg",
                    "type" : {
                      "coding" : [
                        {
                          "system" : "http://terminology.hl7.org/CodeSystem/v3-EntityNamePartQualifierR2",
                          "code" : "STR"
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                      ],
                      "text" : "ATOMOXETINE HYDROCHLORIDE"
                    }
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:249ef22b-d521-4304-a388-6b9035f97b22",
          "resource" : {
            "resourceType" : "ManufacturedItemDefinition",
            "id" : "249ef22b-d521-4304-a388-6b9035f97b22",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-product-batch-formula"
              ]
            },
            "text" : {
              "status" : "extensions",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ManufacturedItemDefinition_249ef22b-d521-4304-a388-6b9035f97b22\"> </a><p class=\"res-header-id\"><b>Generated Narrative: ManufacturedItemDefinition 249ef22b-d521-4304-a388-6b9035f97b22</b></p><a name=\"249ef22b-d521-4304-a388-6b9035f97b22\"> </a><a name=\"hc249ef22b-d521-4304-a388-6b9035f97b22\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-product-batch-formula.html\">Drug Product Batch Formula</a></p></div><p><b>identifier</b>: Oxazepam-Propranolol-BatchFormula</p><p><b>status</b>: Active</p><p><b>name</b>: ATOMOXETINE HYDROCHLORIDE 1mg</p><p><b>manufacturedDoseForm</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C45298}\">Liquid</span></p><p><b>manufacturer</b>: <a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-e875ef93-a730-4c44-bead-53663ae7f501\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></p><blockquote><p><b>property</b></p><p><b>type</b>: <span title=\"Codes:\">Batch Quantity</span></p><p><b>value</b>: 50 liter<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeL = 'L')</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: <span title=\"Codes:\">Batch Utilization</span></p><p><b>value</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C133990}\">Commercial</span></p></blockquote><blockquote><p><b>property</b></p><p><b>type</b>: <span title=\"Codes:\">Batch Formula Additional Information</span></p><p><b>value</b>: </p><div><p>Makes 50 Litres of product, accounting for losses from evaporation and spillage</p>\n</div></blockquote><blockquote><p><b>component</b></p><p><b>type</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42986}\">Solution</span></p><p><b>amount</b>: 53.2 kilogram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codekg = 'kg')</span>, 100 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><blockquote><p><b>constituent</b></p><p><b>Product Batch Strength Textual Extension</b>: 5% atomexetine hydrochloride solution</p><p><b>amount</b>: 25.42 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 0.0477 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-1c1a2a23-1fd7-4487-9682-49877f9f9f77\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 20.5 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 0.0385 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-12cce82f-8595-4860-b7ca-06c9ec0327f2\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 5 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 0.0094 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-45eb4f05-83d9-4819-bb60-96c7c5ce2b76\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 2.27 kilogram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codekg = 'kg')</span>, 4.2652 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-29c0ee76-f62f-41d3-b761-73d5f205e552\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 150 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span>, 0.2818 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-44fad9fd-826a-4f0c-9f25-e0a78d1c4269\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table></blockquote><blockquote><p><b>constituent</b></p><p><b>amount</b>: 50.75 kilogram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codekg = 'kg')</span>, 95.3572 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p><h3>HasIngredients</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-d0574580-7694-4a36-8a27-5bdbccfc5557\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table></blockquote><h3>Properties</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:\">Product Part Identifier</span></td><td><span title=\"Codes:\">solution</span></td></tr></table></blockquote></div>"
            },
            "identifier" : [
              {
                "value" : "Oxazepam-Propranolol-BatchFormula"
              }
            ],
            "status" : "active",
            "name" : "ATOMOXETINE HYDROCHLORIDE 1mg",
            "manufacturedDoseForm" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C45298",
                  "display" : "Liquid"
                }
              ]
            },
            "manufacturer" : [
              {
                "reference" : "urn:uuid:e875ef93-a730-4c44-bead-53663ae7f501"
              }
            ],
            "property" : [
              {
                "type" : {
                  "text" : "Batch Quantity"
                },
                "valueQuantity" : {
                  "value" : 50,
                  "unit" : "liter",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "L"
                }
              },
              {
                "type" : {
                  "text" : "Batch Utilization"
                },
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C133990",
                      "display" : "Commercial"
                    }
                  ]
                }
              },
              {
                "type" : {
                  "text" : "Batch Formula Additional Information"
                },
                "valueMarkdown" : "Makes 50 Litres of product, accounting for losses from evaporation and spillage"
              }
            ],
            "component" : [
              {
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C42986",
                      "display" : "Solution"
                    }
                  ]
                },
                "amount" : [
                  {
                    "value" : 53.2,
                    "unit" : "kilogram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "kg"
                  },
                  {
                    "value" : 100,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                ],
                "constituent" : [
                  {
                    "extension" : [
                      {
                        "url" : "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pq-product-batch-strength-textual-extension",
                        "valueString" : "5% atomexetine hydrochloride solution"
                      }
                    ],
                    "amount" : [
                      {
                        "value" : 25.42,
                        "unit" : "gram",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "g"
                      },
                      {
                        "value" : 0.0477,
                        "unit" : "percent",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "%"
                      }
                    ],
                    "hasIngredient" : [
                      {
                        "reference" : {
                          "reference" : "urn:uuid:1c1a2a23-1fd7-4487-9682-49877f9f9f77"
                        }
                      }
                    ]
                  },
                  {
                    "amount" : [
                      {
                        "value" : 20.5,
                        "unit" : "gram",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "g"
                      },
                      {
                        "value" : 0.0385,
                        "unit" : "percent",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "%"
                      }
                    ],
                    "hasIngredient" : [
                      {
                        "reference" : {
                          "reference" : "urn:uuid:12cce82f-8595-4860-b7ca-06c9ec0327f2"
                        }
                      }
                    ]
                  },
                  {
                    "amount" : [
                      {
                        "value" : 5,
                        "unit" : "gram",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "g"
                      },
                      {
                        "value" : 0.0094,
                        "unit" : "percent",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "%"
                      }
                    ],
                    "hasIngredient" : [
                      {
                        "reference" : {
                          "reference" : "urn:uuid:45eb4f05-83d9-4819-bb60-96c7c5ce2b76"
                        }
                      }
                    ]
                  },
                  {
                    "amount" : [
                      {
                        "value" : 2.27,
                        "unit" : "kilogram",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "kg"
                      },
                      {
                        "value" : 4.2652,
                        "unit" : "percent",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "%"
                      }
                    ],
                    "hasIngredient" : [
                      {
                        "reference" : {
                          "reference" : "urn:uuid:29c0ee76-f62f-41d3-b761-73d5f205e552"
                        }
                      }
                    ]
                  },
                  {
                    "amount" : [
                      {
                        "value" : 150,
                        "unit" : "gram",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "g"
                      },
                      {
                        "value" : 0.2818,
                        "unit" : "percent",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "%"
                      }
                    ],
                    "hasIngredient" : [
                      {
                        "reference" : {
                          "reference" : "urn:uuid:44fad9fd-826a-4f0c-9f25-e0a78d1c4269"
                        }
                      }
                    ]
                  },
                  {
                    "amount" : [
                      {
                        "value" : 50.75,
                        "unit" : "kilogram",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "kg"
                      },
                      {
                        "value" : 95.3572,
                        "unit" : "percent",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "%"
                      }
                    ],
                    "hasIngredient" : [
                      {
                        "reference" : {
                          "reference" : "urn:uuid:d0574580-7694-4a36-8a27-5bdbccfc5557"
                        }
                      }
                    ]
                  }
                ],
                "property" : [
                  {
                    "type" : {
                      "text" : "Product Part Identifier"
                    },
                    "valueCodeableConcept" : {
                      "text" : "solution"
                    }
                  }
                ]
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:1c1a2a23-1fd7-4487-9682-49877f9f9f77",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "1c1a2a23-1fd7-4487-9682-49877f9f9f77",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_1c1a2a23-1fd7-4487-9682-49877f9f9f77\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 1c1a2a23-1fd7-4487-9682-49877f9f9f77</b></p><a name=\"1c1a2a23-1fd7-4487-9682-49877f9f9f77\"> </a><a name=\"hc1c1a2a23-1fd7-4487-9682-49877f9f9f77\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: AtomexetineHydrochlorideBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C82533}\">Active Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-717d868e-6696-4ebb-adf4-63eadb3bf058\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 25.42 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.0477 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"
            },
            "identifier" : {
              "value" : "AtomexetineHydrochlorideBFIngredient"
            },
            "status" : "active",
            "role" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C82533",
                  "display" : "Active Ingredient"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "urn:uuid:717d868e-6696-4ebb-adf4-63eadb3bf058"
                }
              },
              "strength" : [
                {
                  "concentrationQuantity" : {
                    "value" : 25.42,
                    "unit" : "gram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "g"
                  }
                },
                {
                  "concentrationQuantity" : {
                    "value" : 0.0477,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:717d868e-6696-4ebb-adf4-63eadb3bf058",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "717d868e-6696-4ebb-adf4-63eadb3bf058",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-routine-drug-substance"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_717d868e-6696-4ebb-adf4-63eadb3bf058\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition 717d868e-6696-4ebb-adf4-63eadb3bf058</b></p><a name=\"717d868e-6696-4ebb-adf4-63eadb3bf058\"> </a><a name=\"hc717d868e-6696-4ebb-adf4-63eadb3bf058\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-routine-drug-substance.html\">Drug Substance Handle</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><p><b>manufacturer</b>: <a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-e875ef93-a730-4c44-bead-53663ae7f501\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov 57WVB6I2W0}\">57WVB6I2W0</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>ATOMOXETINE HYDROCHLORIDE</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table></div>"
            },
            "classification" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            ],
            "grade" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C134006",
                    "display" : "USP-NF"
                  }
                ]
              }
            ],
            "manufacturer" : [
              {
                "reference" : "urn:uuid:e875ef93-a730-4c44-bead-53663ae7f501"
              }
            ],
            "code" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://fdasis.nlm.nih.gov",
                      "code" : "57WVB6I2W0"
                    }
                  ]
                }
              }
            ],
            "name" : [
              {
                "name" : "ATOMOXETINE HYDROCHLORIDE",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C203355",
                      "display" : "GSRS Preferred Term"
                    }
                  ]
                },
                "preferred" : true
              }
            ]
          }
        },
        {
          "fullUrl" : "urn:uuid:12cce82f-8595-4860-b7ca-06c9ec0327f2",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "12cce82f-8595-4860-b7ca-06c9ec0327f2",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_12cce82f-8595-4860-b7ca-06c9ec0327f2\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 12cce82f-8595-4860-b7ca-06c9ec0327f2</b></p><a name=\"12cce82f-8595-4860-b7ca-06c9ec0327f2\"> </a><a name=\"hc12cce82f-8595-4860-b7ca-06c9ec0327f2\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: GlacialAceticAcidBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-45942749-64db-4f91-88c3-51adb680fed1\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 20.5 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.0385 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"
            },
            "identifier" : {
              "value" : "GlacialAceticAcidBFIngredient"
            },
            "status" : "active",
            "role" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C42637",
                  "display" : "Inactive Ingredient"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "urn:uuid:45942749-64db-4f91-88c3-51adb680fed1"
                }
              },
              "strength" : [
                {
                  "concentrationQuantity" : {
                    "value" : 20.5,
                    "unit" : "gram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "g"
                  }
                },
                {
                  "concentrationQuantity" : {
                    "value" : 0.0385,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:45942749-64db-4f91-88c3-51adb680fed1",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "45942749-64db-4f91-88c3-51adb680fed1",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_45942749-64db-4f91-88c3-51adb680fed1\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition 45942749-64db-4f91-88c3-51adb680fed1</b></p><a name=\"45942749-64db-4f91-88c3-51adb680fed1\"> </a><a name=\"hc45942749-64db-4f91-88c3-51adb680fed1\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov Q40Q9N063P}\">Q40Q9N063P</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>ACETIC ACID</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"
            },
            "classification" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            ],
            "grade" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C134006",
                    "display" : "USP-NF"
                  }
                ]
              }
            ],
            "code" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://fdasis.nlm.nih.gov",
                      "code" : "Q40Q9N063P"
                    }
                  ]
                }
              }
            ],
            "name" : [
              {
                "name" : "ACETIC ACID",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C203355",
                      "display" : "GSRS Preferred Term"
                    }
                  ]
                },
                "preferred" : true
              }
            ],
            "sourceMaterial" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:45eb4f05-83d9-4819-bb60-96c7c5ce2b76",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "45eb4f05-83d9-4819-bb60-96c7c5ce2b76",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_45eb4f05-83d9-4819-bb60-96c7c5ce2b76\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 45eb4f05-83d9-4819-bb60-96c7c5ce2b76</b></p><a name=\"45eb4f05-83d9-4819-bb60-96c7c5ce2b76\"> </a><a name=\"hc45eb4f05-83d9-4819-bb60-96c7c5ce2b76\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: AnhydrousSodiumAcetateBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-07c598ee-3dcf-45b7-b4e5-b24812c22aff\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 5 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.0094 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"
            },
            "identifier" : {
              "value" : "AnhydrousSodiumAcetateBFIngredient"
            },
            "status" : "active",
            "role" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C42637",
                  "display" : "Inactive Ingredient"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "urn:uuid:07c598ee-3dcf-45b7-b4e5-b24812c22aff"
                }
              },
              "strength" : [
                {
                  "concentrationQuantity" : {
                    "value" : 5,
                    "unit" : "gram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "g"
                  }
                },
                {
                  "concentrationQuantity" : {
                    "value" : 0.0094,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:07c598ee-3dcf-45b7-b4e5-b24812c22aff",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "07c598ee-3dcf-45b7-b4e5-b24812c22aff",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_07c598ee-3dcf-45b7-b4e5-b24812c22aff\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition 07c598ee-3dcf-45b7-b4e5-b24812c22aff</b></p><a name=\"07c598ee-3dcf-45b7-b4e5-b24812c22aff\"> </a><a name=\"hc07c598ee-3dcf-45b7-b4e5-b24812c22aff\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov NVG71ZZ7P0}\">NVG71ZZ7P0</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>SODIUM ACETATE ANHYDROUS</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"
            },
            "classification" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            ],
            "grade" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C134006",
                    "display" : "USP-NF"
                  }
                ]
              }
            ],
            "code" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://fdasis.nlm.nih.gov",
                      "code" : "NVG71ZZ7P0"
                    }
                  ]
                }
              }
            ],
            "name" : [
              {
                "name" : "SODIUM ACETATE ANHYDROUS",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C203355",
                      "display" : "GSRS Preferred Term"
                    }
                  ]
                },
                "preferred" : true
              }
            ],
            "sourceMaterial" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:29c0ee76-f62f-41d3-b761-73d5f205e552",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "29c0ee76-f62f-41d3-b761-73d5f205e552",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_29c0ee76-f62f-41d3-b761-73d5f205e552\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 29c0ee76-f62f-41d3-b761-73d5f205e552</b></p><a name=\"29c0ee76-f62f-41d3-b761-73d5f205e552\"> </a><a name=\"hc29c0ee76-f62f-41d3-b761-73d5f205e552\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: MannitolBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-a339a562-e325-4ce6-a830-d25c27b5e2da\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 2.27 kilogram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codekg = 'kg')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 4.2652 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"
            },
            "identifier" : {
              "value" : "MannitolBFIngredient"
            },
            "status" : "active",
            "role" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C42637",
                  "display" : "Inactive Ingredient"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "urn:uuid:a339a562-e325-4ce6-a830-d25c27b5e2da"
                }
              },
              "strength" : [
                {
                  "concentrationQuantity" : {
                    "value" : 2.27,
                    "unit" : "kilogram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "kg"
                  }
                },
                {
                  "concentrationQuantity" : {
                    "value" : 4.2652,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:a339a562-e325-4ce6-a830-d25c27b5e2da",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "a339a562-e325-4ce6-a830-d25c27b5e2da",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_a339a562-e325-4ce6-a830-d25c27b5e2da\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition a339a562-e325-4ce6-a830-d25c27b5e2da</b></p><a name=\"a339a562-e325-4ce6-a830-d25c27b5e2da\"> </a><a name=\"hca339a562-e325-4ce6-a830-d25c27b5e2da\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov 3OWL53L36A}\">3OWL53L36A</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>MANNITOL</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"
            },
            "classification" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            ],
            "grade" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C134006",
                    "display" : "USP-NF"
                  }
                ]
              }
            ],
            "code" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://fdasis.nlm.nih.gov",
                      "code" : "3OWL53L36A"
                    }
                  ]
                }
              }
            ],
            "name" : [
              {
                "name" : "MANNITOL",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C203355",
                      "display" : "GSRS Preferred Term"
                    }
                  ]
                },
                "preferred" : true
              }
            ],
            "sourceMaterial" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:44fad9fd-826a-4f0c-9f25-e0a78d1c4269",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "44fad9fd-826a-4f0c-9f25-e0a78d1c4269",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_44fad9fd-826a-4f0c-9f25-e0a78d1c4269\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient 44fad9fd-826a-4f0c-9f25-e0a78d1c4269</b></p><a name=\"44fad9fd-826a-4f0c-9f25-e0a78d1c4269\"> </a><a name=\"hc44fad9fd-826a-4f0c-9f25-e0a78d1c4269\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: MetacresolBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-c75df5fb-e962-43a6-9dd3-c6682da10a7e\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 150 gram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codeg = 'g')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 0.2818 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"
            },
            "identifier" : {
              "value" : "MetacresolBFIngredient"
            },
            "status" : "active",
            "role" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C42637",
                  "display" : "Inactive Ingredient"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "urn:uuid:c75df5fb-e962-43a6-9dd3-c6682da10a7e"
                }
              },
              "strength" : [
                {
                  "concentrationQuantity" : {
                    "value" : 150,
                    "unit" : "gram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "g"
                  }
                },
                {
                  "concentrationQuantity" : {
                    "value" : 0.2818,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:c75df5fb-e962-43a6-9dd3-c6682da10a7e",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "c75df5fb-e962-43a6-9dd3-c6682da10a7e",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_c75df5fb-e962-43a6-9dd3-c6682da10a7e\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition c75df5fb-e962-43a6-9dd3-c6682da10a7e</b></p><a name=\"c75df5fb-e962-43a6-9dd3-c6682da10a7e\"> </a><a name=\"hcc75df5fb-e962-43a6-9dd3-c6682da10a7e\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov GGO4Y809LO}\">GGO4Y809LO</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>METACRESOL</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"
            },
            "classification" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            ],
            "grade" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C134006",
                    "display" : "USP-NF"
                  }
                ]
              }
            ],
            "code" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://fdasis.nlm.nih.gov",
                      "code" : "GGO4Y809LO"
                    }
                  ]
                }
              }
            ],
            "name" : [
              {
                "name" : "METACRESOL",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C203355",
                      "display" : "GSRS Preferred Term"
                    }
                  ]
                },
                "preferred" : true
              }
            ],
            "sourceMaterial" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:d0574580-7694-4a36-8a27-5bdbccfc5557",
          "resource" : {
            "resourceType" : "Ingredient",
            "id" : "d0574580-7694-4a36-8a27-5bdbccfc5557",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-dp-ingredient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Ingredient_d0574580-7694-4a36-8a27-5bdbccfc5557\"> </a><p class=\"res-header-id\"><b>Generated Narrative: Ingredient d0574580-7694-4a36-8a27-5bdbccfc5557</b></p><a name=\"d0574580-7694-4a36-8a27-5bdbccfc5557\"> </a><a name=\"hcd0574580-7694-4a36-8a27-5bdbccfc5557\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-dp-ingredient.html\">Drug Product Batch Formula Ingredient</a></p></div><p><b>identifier</b>: WaterBFIngredient</p><p><b>status</b>: Active</p><p><b>role</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C42637}\">Inactive Ingredient</span></p><blockquote><p><b>substance</b></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"Bundle-BatchFormulaBundle.html#urn-uuid-c4e5b7c6-2e52-48e3-813b-d227cf29329b\">Bundle: identifier = UUID:a242b79e-b706-49d3-93ba-b4364ab2baa3; type = document; timestamp = 2024-07-01 12:34:56+0000</a></td></tr></table><blockquote><p><b>strength</b></p><p><b>concentration</b>: 50.75 kilogram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codekg = 'kg')</span></p></blockquote><blockquote><p><b>strength</b></p><p><b>concentration</b>: 95.3572 percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  code% = '%')</span></p></blockquote></blockquote></div>"
            },
            "identifier" : {
              "value" : "WaterBFIngredient"
            },
            "status" : "active",
            "role" : {
              "coding" : [
                {
                  "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                  "code" : "C42637",
                  "display" : "Inactive Ingredient"
                }
              ]
            },
            "substance" : {
              "code" : {
                "reference" : {
                  "reference" : "urn:uuid:c4e5b7c6-2e52-48e3-813b-d227cf29329b"
                }
              },
              "strength" : [
                {
                  "concentrationQuantity" : {
                    "value" : 50.75,
                    "unit" : "kilogram",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "kg"
                  }
                },
                {
                  "concentrationQuantity" : {
                    "value" : 95.3572,
                    "unit" : "percent",
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              ]
            }
          }
        },
        {
          "fullUrl" : "urn:uuid:c4e5b7c6-2e52-48e3-813b-d227cf29329b",
          "resource" : {
            "resourceType" : "SubstanceDefinition",
            "id" : "c4e5b7c6-2e52-48e3-813b-d227cf29329b",
            "meta" : {
              "profile" : [
                🔗 "http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient"
              ]
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"SubstanceDefinition_c4e5b7c6-2e52-48e3-813b-d227cf29329b\"> </a><p class=\"res-header-id\"><b>Generated Narrative: SubstanceDefinition c4e5b7c6-2e52-48e3-813b-d227cf29329b</b></p><a name=\"c4e5b7c6-2e52-48e3-813b-d227cf29329b\"> </a><a name=\"hcc4e5b7c6-2e52-48e3-813b-d227cf29329b\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-pqcmc-excipient.html\">Excipient Drug Substance</a></p></div><p><b>classification</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></p><p><b>grade</b>: <span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C134006}\">USP-NF</span></p><h3>Codes</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://fdasis.nlm.nih.gov 059QF0KO0R}\">059QF0KO0R</span></td></tr></table><h3>Names</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Name</b></td><td><b>Type</b></td><td><b>Preferred</b></td></tr><tr><td style=\"display: none\">*</td><td>WATER</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C203355}\">GSRS Preferred Term</span></td><td>true</td></tr></table><h3>SourceMaterials</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl C48807}\">Chemical</span></td></tr></table></div>"
            },
            "classification" : [
              {
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                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            ],
            "grade" : [
              {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C134006",
                    "display" : "USP-NF"
                  }
                ]
              }
            ],
            "code" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://fdasis.nlm.nih.gov",
                      "code" : "059QF0KO0R"
                    }
                  ]
                }
              }
            ],
            "name" : [
              {
                "name" : "WATER",
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                      "code" : "C203355",
                      "display" : "GSRS Preferred Term"
                    }
                  ]
                },
                "preferred" : true
              }
            ],
            "sourceMaterial" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl",
                    "code" : "C48807",
                    "display" : "Chemical"
                  }
                ]
              }
            }
          }
        }
      ]
    }