Release 5 Preview #2

Dosage.profile.xml

Modeling and Methodology Work GroupMaturity Level: N/AStandards Status: Informative

Raw XML (canonical form + also see XML Format Specification)

StructureDefinition for Dosage

<?xml version="1.0" encoding="UTF-8"?>

<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="Dosage"/> 
  <text> 
    <status value="generated"/> 
    <div xmlns="http://www.w3.org/1999/xhtml">
      <table border="0" cellpadding="0" cellspacing="0" style="border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;">
        <tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;">
          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="The logical name of the element">Name</a> 
          </th> 
          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="Information about the use of the element">Flags</a> 
          </th> 
          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="Minimum and Maximum # of times the the element can appear in the instance">Card.</a> 
          </th> 
          <th class="hierarchy" style="width: 100px">
            <a href="formats.html#table" title="Reference to the type of the element">Type</a> 
          </th> 
          <th class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="Additional information about the element">Description &amp; Constraints</a> 
            <span style="float: right">
              <a href="formats.html#table" title="Legend for this format">
                <img alt="doco" src="help16.png" style="background-color: inherit"/> 
              </a> 
            </span> 
          </th> 
        </tr> 
        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;">
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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            exg8Shl1ckRUQVaMVkQ2kCstKCEAOw==" style="background-color: white; background-color: inherit" title="Element"/>  
            <a href="dosage-definitions.html#Dosage" title="Dosage : Indicates how the medication is/was taken or should be taken by the patient.">Dosage</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
            <a href="versions.html#std-process" style="padding-left: 3px; padding-right: 3px; border: 1px grey solid; font-weight: bold; color:
             black; background-color: #fff5e6" title="Standards Status = Trial Use">TU</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="types.html#Element">Element</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">How the medication is/was taken or should be taken
            <br/>  Elements defined in Ancestors: 
            <a href="types.html#Element" title="Unique id for the element within a resource (for internal references). This may be any
             string value that does not contain spaces.">id</a> , 
            <a href="types.html#Element" title="May be used to represent additional information that is not part of the basic definition
             of the element. To make the use of extensions safe and manageable, there is a strict set
             of governance  applied to the definition and use of extensions. Though any implementer
             can define an extension, there is a set of requirements that SHALL be met as part of the
             definition of the extension.">extension</a> , 
            <a href="datatypes.html#BackboneType" title="May be used to represent additional information that is not part of the basic definition
             of the element and that modifies the understanding of the element in which it is contained
             and/or the understanding of the containing element's descendants. Usually modifier elements
             provide negation or qualification. To make the use of extensions safe and manageable,
             there is a strict set of governance applied to the definition and use of extensions. Though
             any implementer can define an extension, there is a set of requirements that SHALL be
             met as part of the definition of the extension. Applications processing a resource are
             required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
             (including cannot change the meaning of modifierExtension itself).">modifierExtension</a> 
          </td> 
        </tr> 

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
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            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAACXBIWXMAAAsTAAALEwEAmpwYAAAARk
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            RgwAAAABJRU5ErkJggg==" style="background-color: #F7F7F7; background-color: inherit" title="Primitive Data Type"/>  
            <a href="dosage-definitions.html#Dosage.sequence" title="Dosage.sequence : Indicates the order in which the dosage instructions should be applied
             or interpreted.">sequence</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#integer">integer</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The order of the dosage instructions</td> 
        </tr> 

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;">
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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          PVYVAgIJrA/sAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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            RgwAAAABJRU5ErkJggg==" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>  
            <a href="dosage-definitions.html#Dosage.text" title="Dosage.text : Free text dosage instructions e.g. SIG.">text</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="datatypes.html#string">string</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">Free text dosage instructions e.g. SIG</td> 
        </tr> 

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
          ORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6E
          EQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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            <a href="dosage-definitions.html#Dosage.additionalInstruction" title="Dosage.additionalInstruction : Supplemental instructions to the patient on how to take
             the medication  (e.g. &quot;with meals&quot; or&quot;take half to one hour before food&quot;)
             or warnings for the patient about the medication (e.g. &quot;may cause drowsiness&quot;
             or &quot;avoid exposure of skin to direct sunlight or sunlamps&quot;).">additionalInstruction</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..*</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Supplemental instruction or warnings to the patient - e.g. &quot;with meals&quot;, &quot;may
             cause drowsiness&quot;
            <br/>  
            <a href="valueset-additional-instruction-codes.html" title="A coded concept identifying additional instructions such as &quot;take with water&quot;
             or &quot;avoid operating heavy machinery&quot;.">SNOMED CT Additional Dosage Instructions</a>  (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.">Example</a> )
            <br/>  
          </td> 
        </tr> 

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white;">
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVBORw0KGg
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            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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            RgwAAAABJRU5ErkJggg==" style="background-color: white; background-color: inherit" title="Primitive Data Type"/>  
            <a href="dosage-definitions.html#Dosage.patientInstruction" title="Dosage.patientInstruction : Instructions in terms that are understood by the patient or
             consumer.">patientInstruction</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="datatypes.html#string">string</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">Patient or consumer oriented instructions</td> 
        </tr> 

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(data:image/png;base64,iVB
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          EQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)">
            <img alt="." class="hierarchy" src="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="datatypes.html#Timing">Timing</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">When medication should be administered</td> 
        </tr> 

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             the Medication (CodeableConcept).">asNeeded[x]</a> 
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">Take &quot;as needed&quot; (for x)
            <br/>  
            <a href="valueset-medication-as-needed-reason.html" title="A coded concept identifying the precondition that should be met or evaluated prior to
             consuming or administering a medication dose.  For example &quot;pain&quot;, &quot;30
             minutes prior to sexual intercourse&quot;, &quot;on flare-up&quot; etc.">SNOMED CT Medication As Needed Reason Codes</a>  (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.">Example</a> )
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            <span title="Value of &quot;true&quot; or &quot;false&quot;">asNeededBoolean</span> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="datatypes.html#boolean">boolean</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <span title="A concept that may be defined by a formal reference to a terminology or ontology or may
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
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            <a href="dosage-definitions.html#Dosage.site" title="Dosage.site : Body site to administer to.">site</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Body site to administer to
            <br/>  
            <a href="valueset-approach-site-codes.html" title="A coded concept describing the site location the medicine enters into or onto the body.">SNOMED CT Anatomical Structure for Administration Site Codes</a>  (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.">Example</a> )
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            <a href="dosage-definitions.html#Dosage.route" title="Dosage.route : How drug should enter body.">route</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">How drug should enter body
            <br/>  
            <a href="valueset-route-codes.html" title="A coded concept describing the route or physiological path of administration of a therapeutic
             agent into or onto the body of a subject.">SNOMED CT Route Codes</a>  (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.">Example</a> )
          </td> 
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            <a href="dosage-definitions.html#Dosage.method" title="Dosage.method : Technique for administering medication.">method</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">Technique for administering medication
            <br/>  
            <a href="valueset-administration-method-codes.html" title="A coded concept describing the technique by which the medicine is administered.">SNOMED CT Administration Method Codes</a>  (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.">Example</a> )
          </td> 
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          PVYVAgIJrA/sAAAAASUVORK5CYII=)">
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            <a href="dosage-definitions.html#Dosage.doseAndRate" title="Dosage.doseAndRate : The amount of medication administered.">doseAndRate</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            <a href="types.html#Element">Element</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            <br/>  
          </td> 
        </tr> 

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            <a href="dosage-definitions.html#Dosage.doseAndRate.type" title="Dosage.doseAndRate.type : The kind of dose or rate specified, for example, ordered or
             calculated.">type</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">0..1</td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a> 
          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
           solid; padding:0px 4px 0px 4px">The kind of dose or rate specified
            <br/>  
            <a href="valueset-dose-rate-type.html" title="The kind of dose or rate specified.">DoseAndRateType</a>  (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included.">Example</a> )
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            <a href="dosage-definitions.html#Dosage.doseAndRate.dose_x_" title="Dosage.doseAndRate.dose[x] : Amount of medication per dose.">dose[x]</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
           padding:0px 4px 0px 4px"/> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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        </tr> 

        <tr style="border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7;">
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            <span title="A set of ordered Quantities defined by a low and high limit.">doseRange</span> 
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <span title="A relationship of two Quantity values - expressed as a numerator and a denominator.">rateRatio</span> 
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            <a href="datatypes.html#Ratio">Ratio</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="dosage-definitions.html#Dosage.maxDosePerAdministration" title="Dosage.maxDosePerAdministration : Upper limit on medication per administration.">maxDosePerAdministration</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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          </td> 
          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid;
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            <a href="dosage-definitions.html#Dosage.maxDosePerLifetime" title="Dosage.maxDosePerLifetime : Upper limit on medication per lifetime of the patient.">maxDosePerLifetime</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="elementdefinition-definitions.html#ElementDefinition.isSummary" style="padding-left: 3px; padding-right: 3px; color: black; null" title="This element is included in summaries">Σ</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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            <a href="datatypes.html#SimpleQuantity">SimpleQuantity</a> 
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          <td class="hierarchy" style="vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0
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        <tr> 
          <td class="hierarchy" colspan="5">
            <br/>  
            <a href="formats.html#table" title="Legend for this format">
              <img alt="doco" src="help16.png" style="background-color: inherit"/>  Documentation for this format
            </a> 
          </td> 
        </tr> 
      </table> 
    </div> 
  </text> 
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="trial-use"/> 
  </extension> 
  <url value="http://hl7.org/fhir/StructureDefinition/Dosage"/> 
  <version value="4.4.0"/> 
  <name value="Dosage"/> 
  <status value="draft"/> 
  <date value="2020-07-02T00:59:53+00:00"/> 
  <publisher value="HL7 FHIR Standard"/> 
  <contact> 
    <telecom> 
      <system value="url"/> 
      <value value="http://hl7.org/fhir"/> 
    </telecom> 
  </contact> 
  <description value="Base StructureDefinition for Dosage Type: Indicates how the medication is/was taken or
   should be taken by the patient."/> 
  <fhirVersion value="4.4.0"/> 
  <mapping> 
    <identity value="rim"/> 
    <uri value="http://hl7.org/v3"/> 
    <name value="RIM Mapping"/> 
  </mapping> 
  <mapping> 
    <identity value="v2"/> 
    <uri value="http://hl7.org/v2"/> 
    <name value="HL7 v2 Mapping"/> 
  </mapping> 
  <kind value="complex-type"/> 
  <abstract value="false"/> 
  <type value="Dosage"/> 
  <baseDefinition value="http://hl7.org/fhir/StructureDefinition/BackboneType"/> 
  <derivation value="specialization"/> 
  <snapshot> 
    <element id="Dosage">
      <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
        <valueCode value="trial-use"/> 
      </extension> 
      <path value="Dosage"/> 
      <short value="How the medication is/was taken or should be taken"/> 
      <definition value="Indicates how the medication is/was taken or should be taken by the patient."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Dosage"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT]"/> 
      </mapping> 
    </element> 
    <element id="Dosage.id">
      <path value="Dosage.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      <definition value="Unique id for the element within a resource (for internal references). This may be any
       string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
    <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
       (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUri value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="Dosage.extension">
      <path value="Dosage.extension"/> 
      <slicing> 
        <discriminator> 
          <type value="value"/> 
          <path value="url"/> 
        </discriminator> 
        <description value="Extensions are always sliced by (at least) url"/> 
        <rules value="open"/> 
      </slicing> 
      <short value="Additional content defined by implementations"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and manageable, there is a strict set
       of governance  applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part of the
       definition of the extension."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <constraint> 
        <key value="ext-1"/> 
        <severity value="error"/> 
        <human value="Must have either extensions or value[x], not both"/> 
        <expression value="extension.exists() != value.exists()"/> 
        <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Extension"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="Dosage.modifierExtension">
      <path value="Dosage.modifierExtension"/> 
      <short value="Extensions that cannot be ignored even if unrecognized"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element and that modifies the understanding of the element in which it is contained
       and/or the understanding of the containing element's descendants. Usually modifier elements
       provide negation or qualification. To make the use of extensions safe and manageable,
       there is a strict set of governance applied to the definition and use of extensions. Though
       any implementer can define an extension, there is a set of requirements that SHALL be
       met as part of the definition of the extension. Applications processing a resource are
       required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource
       (including cannot change the meaning of modifierExtension itself)."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/> 
      <requirements value="Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly
       distinguished from the vast majority of extensions which can be safely ignored.  This
       promotes interoperability by eliminating the need for implementers to prohibit the presence
       of extensions. For further information, see the [definition of modifier extensions](extensibility.ht
      ml#modifierExtension)."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <alias value="modifiers"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="BackboneType.modifierExtension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <constraint> 
        <key value="ext-1"/> 
        <severity value="error"/> 
        <human value="Must have either extensions or value[x], not both"/> 
        <expression value="extension.exists() != value.exists()"/> 
        <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Extension"/> 
      </constraint> 
      <isModifier value="true"/> 
      <isModifierReason value="Modifier extensions are expected to modify the meaning or interpretation of the element
       that contains them"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="N/A"/> 
      </mapping> 
    </element> 
    <element id="Dosage.sequence">
      <path value="Dosage.sequence"/> 
      <short value="The order of the dosage instructions"/> 
      <definition value="Indicates the order in which the dosage instructions should be applied or interpreted."/> 
      <requirements value="If the sequence number of multiple Dosages is the same, then it is implied that the instructions
       are to be treated as concurrent.  If the sequence number is different, then the Dosages
       are intended to be sequential."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.sequence"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="integer"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="TQ1-1"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.text">
      <path value="Dosage.text"/> 
      <short value="Free text dosage instructions e.g. SIG"/> 
      <definition value="Free text dosage instructions e.g. SIG."/> 
      <requirements value="Free text dosage instructions can be used for cases where the instructions are too complex
       to code.  The content of this attribute does not include the name or description of the
       medication. When coded instructions are present, the free text instructions may still
       be present for display to humans taking or administering the medication. It is expected
       that the text instructions will always be populated.  If the dosage.timing attribute is
       also populated, then the dosage.text should reflect the same information as the timing.
        Additional information about administration or preparation of the medication should be
       included as text."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.text"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="string"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-6; RXE-21"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.additionalInstruction">
      <path value="Dosage.additionalInstruction"/> 
      <short value="Supplemental instruction or warnings to the patient - e.g. &quot;with meals&quot;, &quot;may
       cause drowsiness&quot;"/> 
      <definition value="Supplemental instructions to the patient on how to take the medication  (e.g. &quot;with
       meals&quot; or&quot;take half to one hour before food&quot;) or warnings for the patient
       about the medication (e.g. &quot;may cause drowsiness&quot; or &quot;avoid exposure of
       skin to direct sunlight or sunlamps&quot;)."/> 
      <comment value="Information about administration or preparation of the medication (e.g. &quot;infuse as
       rapidly as possibly via intraperitoneal port&quot; or &quot;immediately following drug
       x&quot;) should be populated in dosage.text."/> 
      <requirements value="Additional instruction is intended to be coded, but where no code exists, the element
       could include text.  For example, &quot;Swallow with plenty of water&quot; which might
       or might not be coded."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Dosage.additionalInstruction"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="AdditionalInstruction"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept identifying additional instructions such as &quot;take with water&quot;
         or &quot;avoid operating heavy machinery&quot;."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/additional-instruction-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-7"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.patientInstruction">
      <path value="Dosage.patientInstruction"/> 
      <short value="Patient or consumer oriented instructions"/> 
      <definition value="Instructions in terms that are understood by the patient or consumer."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.patientInstruction"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="string"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-7"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.timing">
      <path value="Dosage.timing"/> 
      <short value="When medication should be administered"/> 
      <definition value="When medication should be administered."/> 
      <comment value="This attribute might not always be populated while the Dosage.text is expected to be populated.
        If both are populated, then the Dosage.text should reflect the content of the Dosage.timing."/> 
      <requirements value="The timing schedule for giving the medication to the patient. This  data type allows many
       different expressions. For example: &quot;Every 8 hours&quot;; &quot;Three times a day&quot;;
       &quot;1/2 an hour before breakfast for 10 days from 23-Dec 2011:&quot;; &quot;15 Oct 2013,
       17 Oct 2013 and 1 Nov 2013&quot;.  Sometimes, a rate can imply duration when expressed
       as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However,
       when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is
       needed to convey the infuse over time period."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.timing"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Timing"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".effectiveTime"/> 
      </mapping> 
    </element> 
    <element id="Dosage.asNeeded[x]">
      <path value="Dosage.asNeeded[x]"/> 
      <short value="Take &quot;as needed&quot; (for x)"/> 
      <definition value="Indicates whether the Medication is only taken when needed within a specific dosing schedule
       (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept)."/> 
      <comment value="Can express &quot;as needed&quot; without a reason by setting the Boolean = True.  In
       this case the CodeableConcept is not populated.  Or you can express &quot;as needed&quot;
       with a reason by including the CodeableConcept.  In this case the Boolean is assumed to
       be True.  If you set the Boolean to False, then the dose is given according to the schedule
       and is not &quot;prn&quot; or &quot;as needed&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.asNeeded[x]"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="boolean"/> 
      </type> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="MedicationAsNeededReason"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept identifying the precondition that should be met or evaluated prior to
         consuming or administering a medication dose.  For example &quot;pain&quot;, &quot;30
         minutes prior to sexual intercourse&quot;, &quot;on flare-up&quot; etc."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/medication-as-needed-reason"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="TQ1-9"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=&quot;as
         needed&quot;].value=boolean or codable concept"/> 
      </mapping> 
    </element> 
    <element id="Dosage.site">
      <path value="Dosage.site"/> 
      <short value="Body site to administer to"/> 
      <definition value="Body site to administer to."/> 
      <comment value="If the use case requires attributes from the BodySite resource (e.g. to identify and track
       separately) then use the standard extension [bodySite](extension-bodysite.html).  May
       be a summary code, or a reference to a very precise definition of the location, or both."/> 
      <requirements value="A coded specification of the anatomic site where the medication first enters the body."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.site"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="MedicationAdministrationSite"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept describing the site location the medicine enters into or onto the body."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/approach-site-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXR-2"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".approachSiteCode"/> 
      </mapping> 
    </element> 
    <element id="Dosage.route">
      <path value="Dosage.route"/> 
      <short value="How drug should enter body"/> 
      <definition value="How drug should enter body."/> 
      <requirements value="A code specifying the route or physiological path of administration of a therapeutic agent
       into or onto a patient's body."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.route"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="RouteOfAdministration"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept describing the route or physiological path of administration of a therapeutic
         agent into or onto the body of a subject."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/route-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXR-1"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".routeCode"/> 
      </mapping> 
    </element> 
    <element id="Dosage.method">
      <path value="Dosage.method"/> 
      <short value="Technique for administering medication"/> 
      <definition value="Technique for administering medication."/> 
      <comment value="Terminologies used often pre-coordinate this term with the route and or form of administration."/> 
      <requirements value="A coded value indicating the method by which the medication is introduced into or onto
       the body. Most commonly used for injections.  For examples, Slow Push; Deep IV."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.method"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="MedicationAdministrationMethod"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept describing the technique by which the medicine is administered."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/administration-method-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXR-4"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value="SubstanceAdministration.methodCode"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate">
      <path value="Dosage.doseAndRate"/> 
      <short value="Amount of medication administered"/> 
      <definition value="The amount of medication administered."/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Dosage.doseAndRate"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Element"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="TQ1-2"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value="SubstanceAdministration.doseQuantity; SubstanceAdministration.RateQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.id">
      <path value="Dosage.doseAndRate.id"/> 
      <representation value="xmlAttr"/> 
      <short value="Unique id for inter-element referencing"/> 
      <definition value="Unique id for the element within a resource (for internal references). This may be any
       string value that does not contain spaces."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Element.id"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
    <!--  Note: special primitive values have a FHIRPath system type. e.g. this is compiler magic
       (j)  -->
      <type> 
        <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type">
          <valueUri value="string"/> 
        </extension> 
        <code value="http://hl7.org/fhirpath/System.String"/> 
      </type> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.extension">
      <path value="Dosage.doseAndRate.extension"/> 
      <slicing> 
        <discriminator> 
          <type value="value"/> 
          <path value="url"/> 
        </discriminator> 
        <description value="Extensions are always sliced by (at least) url"/> 
        <rules value="open"/> 
      </slicing> 
      <short value="Additional content defined by implementations"/> 
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. To make the use of extensions safe and manageable, there is a strict set
       of governance  applied to the definition and use of extensions. Though any implementer
       can define an extension, there is a set of requirements that SHALL be met as part of the
       definition of the extension."/> 
      <comment value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/> 
      <alias value="extensions"/> 
      <alias value="user content"/> 
      <min value="0"/> 
      <max value="*"/> 
      <base> 
        <path value="Element.extension"/> 
        <min value="0"/> 
        <max value="*"/> 
      </base> 
      <type> 
        <code value="Extension"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <constraint> 
        <key value="ext-1"/> 
        <severity value="error"/> 
        <human value="Must have either extensions or value[x], not both"/> 
        <expression value="extension.exists() != value.exists()"/> 
        <xpath value="exists(f:extension)!=exists(f:*[starts-with(local-name(.), &quot;value&quot;)])"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Extension"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="false"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="n/a"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.type">
      <path value="Dosage.doseAndRate.type"/> 
      <short value="The kind of dose or rate specified"/> 
      <definition value="The kind of dose or rate specified, for example, ordered or calculated."/> 
      <requirements value="If the type is not populated, assume to be &quot;ordered&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.doseAndRate.type"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DoseAndRateType"/> 
        </extension> 
        <strength value="example"/> 
        <description value="The kind of dose or rate specified."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/dose-rate-type"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-21; RXE-23"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.dose[x]">
      <path value="Dosage.doseAndRate.dose[x]"/> 
      <short value="Amount of medication per dose"/> 
      <definition value="Amount of medication per dose."/> 
      <comment value="Note that this specifies the quantity of the specified medication, not the quantity for
       each active ingredient(s). Each ingredient amount can be communicated in the Medication
       resource. For example, if one wants to communicate that a tablet was 375 mg, where the
       dose was one tablet, you can use the Medication resource to document that the tablet was
       comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only
       need to use the Medication resource to indicate this was a tablet. If the example were
       an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed
       in 500 ml of some IV solution, then this would all be communicated in the Medication resource.
       If the administration is not intended to be instantaneous (rate is present or timing has
       a duration), this can be specified to convey the total amount to be administered over
       the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used
       to convey that this should be done over 4 hours."/> 
      <requirements value="The amount of therapeutic or other substance given at one administration event."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.doseAndRate.dose[x]"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Range"/> 
      </type> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-2, RXE-3"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".doseQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.rate[x]">
      <path value="Dosage.doseAndRate.rate[x]"/> 
      <short value="Amount of medication per unit of time"/> 
      <definition value="Amount of medication per unit of time."/> 
      <comment value="It is possible to supply both a rate and a doseQuantity to provide full details about
       how the medication is to be administered and supplied. If the rate is intended to change
       over time, depending on local rules/regulations, each change should be captured as a new
       version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest
       with the new rate.

It is possible to specify a rate over time (for example, 100 ml/hour) using either the
       rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability
       to parse UCUM grammer where ml/hour is included rather than a specific ratio where the
       time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified,
       the use of rateRatio may be more semantically correct than specifying using a rateQuantity
       of 250 mg/hour."/> 
      <requirements value="Identifies the speed with which the medication was or will be introduced into the patient.
       Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed
       as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200
       mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as
       total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However,
       when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is
       needed to convey the infuse over time period."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.doseAndRate.rate[x]"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Ratio"/> 
      </type> 
      <type> 
        <code value="Range"/> 
      </type> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXE22, RXE23, RXE-24"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".rateQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.maxDosePerPeriod">
      <path value="Dosage.maxDosePerPeriod"/> 
      <short value="Upper limit on medication per unit of time"/> 
      <definition value="Upper limit on medication per unit of time."/> 
      <comment value="This is intended for use as an adjunct to the dosage when there is an upper cap.  For
       example &quot;2 tablets every 4 hours to a maximum of 8/day&quot;."/> 
      <requirements value="The maximum total quantity of a therapeutic substance that may be administered to a subject
       over the period of time.  For example, 1000mg in 24 hours."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.maxDosePerPeriod"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Ratio"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-23, RXE-19"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".maxDoseQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.maxDosePerAdministration">
      <path value="Dosage.maxDosePerAdministration"/> 
      <short value="Upper limit on medication per administration"/> 
      <definition value="Upper limit on medication per administration."/> 
      <comment value="This is intended for use as an adjunct to the dosage when there is an upper cap.  For
       example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum
       2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration
       of 2 mg."/> 
      <requirements value="The maximum total quantity of a therapeutic substance that may be administered to a subject
       per administration."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.maxDosePerAdministration"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="not supported"/> 
      </mapping> 
    </element> 
    <element id="Dosage.maxDosePerLifetime">
      <path value="Dosage.maxDosePerLifetime"/> 
      <short value="Upper limit on medication per lifetime of the patient"/> 
      <definition value="Upper limit on medication per lifetime of the patient."/> 
      <requirements value="The maximum total quantity of a therapeutic substance that may be administered per lifetime
       of the subject."/> 
      <min value="0"/> 
      <max value="1"/> 
      <base> 
        <path value="Dosage.maxDosePerLifetime"/> 
        <min value="0"/> 
        <max value="1"/> 
      </base> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <constraint> 
        <key value="ele-1"/> 
        <severity value="error"/> 
        <human value="All FHIR elements must have a @value or children"/> 
        <expression value="hasValue() or (children().count() &gt; id.count())"/> 
        <xpath value="@value|f:*|h:div"/> 
        <source value="http://hl7.org/fhir/StructureDefinition/Element"/> 
      </constraint> 
      <isModifier value="false"/> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="not supported"/> 
      </mapping> 
    </element> 
  </snapshot> 
  <differential> 
    <element id="Dosage">
      <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
        <valueCode value="trial-use"/> 
      </extension> 
      <path value="Dosage"/> 
      <short value="How the medication is/was taken or should be taken"/> 
      <definition value="Indicates how the medication is/was taken or should be taken by the patient."/> 
      <min value="0"/> 
      <max value="*"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".outboundRelationship[typeCode=COMP].target[classCode=SBADM, moodCode=INT]"/> 
      </mapping> 
    </element> 
    <element id="Dosage.sequence">
      <path value="Dosage.sequence"/> 
      <short value="The order of the dosage instructions"/> 
      <definition value="Indicates the order in which the dosage instructions should be applied or interpreted."/> 
      <requirements value="If the sequence number of multiple Dosages is the same, then it is implied that the instructions
       are to be treated as concurrent.  If the sequence number is different, then the Dosages
       are intended to be sequential."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="integer"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="TQ1-1"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.text">
      <path value="Dosage.text"/> 
      <short value="Free text dosage instructions e.g. SIG"/> 
      <definition value="Free text dosage instructions e.g. SIG."/> 
      <requirements value="Free text dosage instructions can be used for cases where the instructions are too complex
       to code.  The content of this attribute does not include the name or description of the
       medication. When coded instructions are present, the free text instructions may still
       be present for display to humans taking or administering the medication. It is expected
       that the text instructions will always be populated.  If the dosage.timing attribute is
       also populated, then the dosage.text should reflect the same information as the timing.
        Additional information about administration or preparation of the medication should be
       included as text."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="string"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-6; RXE-21"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.additionalInstruction">
      <path value="Dosage.additionalInstruction"/> 
      <short value="Supplemental instruction or warnings to the patient - e.g. &quot;with meals&quot;, &quot;may
       cause drowsiness&quot;"/> 
      <definition value="Supplemental instructions to the patient on how to take the medication  (e.g. &quot;with
       meals&quot; or&quot;take half to one hour before food&quot;) or warnings for the patient
       about the medication (e.g. &quot;may cause drowsiness&quot; or &quot;avoid exposure of
       skin to direct sunlight or sunlamps&quot;)."/> 
      <comment value="Information about administration or preparation of the medication (e.g. &quot;infuse as
       rapidly as possibly via intraperitoneal port&quot; or &quot;immediately following drug
       x&quot;) should be populated in dosage.text."/> 
      <requirements value="Additional instruction is intended to be coded, but where no code exists, the element
       could include text.  For example, &quot;Swallow with plenty of water&quot; which might
       or might not be coded."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="AdditionalInstruction"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept identifying additional instructions such as &quot;take with water&quot;
         or &quot;avoid operating heavy machinery&quot;."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/additional-instruction-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-7"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.patientInstruction">
      <path value="Dosage.patientInstruction"/> 
      <short value="Patient or consumer oriented instructions"/> 
      <definition value="Instructions in terms that are understood by the patient or consumer."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="string"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-7"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".text"/> 
      </mapping> 
    </element> 
    <element id="Dosage.timing">
      <path value="Dosage.timing"/> 
      <short value="When medication should be administered"/> 
      <definition value="When medication should be administered."/> 
      <comment value="This attribute might not always be populated while the Dosage.text is expected to be populated.
        If both are populated, then the Dosage.text should reflect the content of the Dosage.timing."/> 
      <requirements value="The timing schedule for giving the medication to the patient. This  data type allows many
       different expressions. For example: &quot;Every 8 hours&quot;; &quot;Three times a day&quot;;
       &quot;1/2 an hour before breakfast for 10 days from 23-Dec 2011:&quot;; &quot;15 Oct 2013,
       17 Oct 2013 and 1 Nov 2013&quot;.  Sometimes, a rate can imply duration when expressed
       as total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However,
       when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is
       needed to convey the infuse over time period."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Timing"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".effectiveTime"/> 
      </mapping> 
    </element> 
    <element id="Dosage.asNeeded[x]">
      <path value="Dosage.asNeeded[x]"/> 
      <short value="Take &quot;as needed&quot; (for x)"/> 
      <definition value="Indicates whether the Medication is only taken when needed within a specific dosing schedule
       (Boolean option), or it indicates the precondition for taking the Medication (CodeableConcept)."/> 
      <comment value="Can express &quot;as needed&quot; without a reason by setting the Boolean = True.  In
       this case the CodeableConcept is not populated.  Or you can express &quot;as needed&quot;
       with a reason by including the CodeableConcept.  In this case the Boolean is assumed to
       be True.  If you set the Boolean to False, then the dose is given according to the schedule
       and is not &quot;prn&quot; or &quot;as needed&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="boolean"/> 
      </type> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="MedicationAsNeededReason"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept identifying the precondition that should be met or evaluated prior to
         consuming or administering a medication dose.  For example &quot;pain&quot;, &quot;30
         minutes prior to sexual intercourse&quot;, &quot;on flare-up&quot; etc."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/medication-as-needed-reason"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="TQ1-9"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".outboundRelationship[typeCode=PRCN].target[classCode=OBS, moodCode=EVN, code=&quot;as
         needed&quot;].value=boolean or codable concept"/> 
      </mapping> 
    </element> 
    <element id="Dosage.site">
      <path value="Dosage.site"/> 
      <short value="Body site to administer to"/> 
      <definition value="Body site to administer to."/> 
      <comment value="If the use case requires attributes from the BodySite resource (e.g. to identify and track
       separately) then use the standard extension [bodySite](extension-bodysite.html).  May
       be a summary code, or a reference to a very precise definition of the location, or both."/> 
      <requirements value="A coded specification of the anatomic site where the medication first enters the body."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="MedicationAdministrationSite"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept describing the site location the medicine enters into or onto the body."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/approach-site-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXR-2"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".approachSiteCode"/> 
      </mapping> 
    </element> 
    <element id="Dosage.route">
      <path value="Dosage.route"/> 
      <short value="How drug should enter body"/> 
      <definition value="How drug should enter body."/> 
      <requirements value="A code specifying the route or physiological path of administration of a therapeutic agent
       into or onto a patient's body."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="RouteOfAdministration"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept describing the route or physiological path of administration of a therapeutic
         agent into or onto the body of a subject."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/route-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXR-1"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".routeCode"/> 
      </mapping> 
    </element> 
    <element id="Dosage.method">
      <path value="Dosage.method"/> 
      <short value="Technique for administering medication"/> 
      <definition value="Technique for administering medication."/> 
      <comment value="Terminologies used often pre-coordinate this term with the route and or form of administration."/> 
      <requirements value="A coded value indicating the method by which the medication is introduced into or onto
       the body. Most commonly used for injections.  For examples, Slow Push; Deep IV."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="MedicationAdministrationMethod"/> 
        </extension> 
        <strength value="example"/> 
        <description value="A coded concept describing the technique by which the medicine is administered."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/administration-method-codes"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXR-4"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value="SubstanceAdministration.methodCode"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate">
      <path value="Dosage.doseAndRate"/> 
      <short value="Amount of medication administered"/> 
      <definition value="The amount of medication administered."/> 
      <min value="0"/> 
      <max value="*"/> 
      <type> 
        <code value="Element"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="TQ1-2"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value="SubstanceAdministration.doseQuantity; SubstanceAdministration.RateQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.type">
      <path value="Dosage.doseAndRate.type"/> 
      <short value="The kind of dose or rate specified"/> 
      <definition value="The kind of dose or rate specified, for example, ordered or calculated."/> 
      <requirements value="If the type is not populated, assume to be &quot;ordered&quot;."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="CodeableConcept"/> 
      </type> 
      <isSummary value="true"/> 
      <binding> 
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="DoseAndRateType"/> 
        </extension> 
        <strength value="example"/> 
        <description value="The kind of dose or rate specified."/> 
        <valueSet value="http://hl7.org/fhir/ValueSet/dose-rate-type"/> 
      </binding> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-21; RXE-23"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.dose[x]">
      <path value="Dosage.doseAndRate.dose[x]"/> 
      <short value="Amount of medication per dose"/> 
      <definition value="Amount of medication per dose."/> 
      <comment value="Note that this specifies the quantity of the specified medication, not the quantity for
       each active ingredient(s). Each ingredient amount can be communicated in the Medication
       resource. For example, if one wants to communicate that a tablet was 375 mg, where the
       dose was one tablet, you can use the Medication resource to document that the tablet was
       comprised of 375 mg of drug XYZ. Alternatively if the dose was 375 mg, then you may only
       need to use the Medication resource to indicate this was a tablet. If the example were
       an IV such as dopamine and you wanted to communicate that 400mg of dopamine was mixed
       in 500 ml of some IV solution, then this would all be communicated in the Medication resource.
       If the administration is not intended to be instantaneous (rate is present or timing has
       a duration), this can be specified to convey the total amount to be administered over
       the period of time as indicated by the schedule e.g. 500 ml in dose, with timing used
       to convey that this should be done over 4 hours."/> 
      <requirements value="The amount of therapeutic or other substance given at one administration event."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Range"/> 
      </type> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-2, RXE-3"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".doseQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.doseAndRate.rate[x]">
      <path value="Dosage.doseAndRate.rate[x]"/> 
      <short value="Amount of medication per unit of time"/> 
      <definition value="Amount of medication per unit of time."/> 
      <comment value="It is possible to supply both a rate and a doseQuantity to provide full details about
       how the medication is to be administered and supplied. If the rate is intended to change
       over time, depending on local rules/regulations, each change should be captured as a new
       version of the MedicationRequest with an updated rate, or captured with a new MedicationRequest
       with the new rate.

It is possible to specify a rate over time (for example, 100 ml/hour) using either the
       rateRatio and rateQuantity.  The rateQuantity approach requires systems to have the capability
       to parse UCUM grammer where ml/hour is included rather than a specific ratio where the
       time is specified as the denominator.  Where a rate such as 500ml over 2 hours is specified,
       the use of rateRatio may be more semantically correct than specifying using a rateQuantity
       of 250 mg/hour."/> 
      <requirements value="Identifies the speed with which the medication was or will be introduced into the patient.
       Typically the rate for an infusion e.g. 100 ml per 1 hour or 100 ml/hr.  May also be expressed
       as a rate per unit of time e.g. 500 ml per 2 hours.   Other examples: 200 mcg/min or 200
       mcg/1 minute; 1 liter/8 hours.  Sometimes, a rate can imply duration when expressed as
       total volume / duration (e.g.  500mL/2 hours implies a duration of 2 hours).  However,
       when rate doesn't imply duration (e.g. 250mL/hour), then the timing.repeat.duration is
       needed to convey the infuse over time period."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Ratio"/> 
      </type> 
      <type> 
        <code value="Range"/> 
      </type> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXE22, RXE23, RXE-24"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".rateQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.maxDosePerPeriod">
      <path value="Dosage.maxDosePerPeriod"/> 
      <short value="Upper limit on medication per unit of time"/> 
      <definition value="Upper limit on medication per unit of time."/> 
      <comment value="This is intended for use as an adjunct to the dosage when there is an upper cap.  For
       example &quot;2 tablets every 4 hours to a maximum of 8/day&quot;."/> 
      <requirements value="The maximum total quantity of a therapeutic substance that may be administered to a subject
       over the period of time.  For example, 1000mg in 24 hours."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Ratio"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="v2"/> 
        <map value="RXO-23, RXE-19"/> 
      </mapping> 
      <mapping> 
        <identity value="rim"/> 
        <map value=".maxDoseQuantity"/> 
      </mapping> 
    </element> 
    <element id="Dosage.maxDosePerAdministration">
      <path value="Dosage.maxDosePerAdministration"/> 
      <short value="Upper limit on medication per administration"/> 
      <definition value="Upper limit on medication per administration."/> 
      <comment value="This is intended for use as an adjunct to the dosage when there is an upper cap.  For
       example, a body surface area related dose with a maximum amount, such as 1.5 mg/m2 (maximum
       2 mg) IV over 5 – 10 minutes would have doseQuantity of 1.5 mg/m2 and maxDosePerAdministration
       of 2 mg."/> 
      <requirements value="The maximum total quantity of a therapeutic substance that may be administered to a subject
       per administration."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="not supported"/> 
      </mapping> 
    </element> 
    <element id="Dosage.maxDosePerLifetime">
      <path value="Dosage.maxDosePerLifetime"/> 
      <short value="Upper limit on medication per lifetime of the patient"/> 
      <definition value="Upper limit on medication per lifetime of the patient."/> 
      <requirements value="The maximum total quantity of a therapeutic substance that may be administered per lifetime
       of the subject."/> 
      <min value="0"/> 
      <max value="1"/> 
      <type> 
        <code value="Quantity"/> 
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/> 
      </type> 
      <isSummary value="true"/> 
      <mapping> 
        <identity value="rim"/> 
        <map value="not supported"/> 
      </mapping> 
    </element> 
  </differential> 
</StructureDefinition> 

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.