**Code** | **Display** | **Definition** |

systematic-assessment | Systematic Assessment | Any method of routinely determining whether or not specific outcomes (e.g. adverse events) have occurred, for example through a standard questionnaire, regular investigator assessment, regular laboratory testing, or other method |

non-systematic-assessment | Non-Systematic Assessment | Any non-systematic method for determining whether or not adverse events have occurred, such as self-reporting by participants or occasional assessment/testing |

mean | Mean | Aggregated using mean of observed values. |

median | Median | Aggregated using median of observed values. |

mean-of-mean | Mean of Means | Aggregated using mean of means (e.g. study mean values). |

mean-of-median | Mean of Medians | Aggregated using mean of medians (e.g. study median values). |

median-of-mean | Median of Means | Aggregated using median of means (e.g. study mean values). |

median-of-median | Median of Medians | Aggregated using median of medians (e.g. study median values). |