{"author":[{"name":"Brian S. Alper, MD, MSPH"}],"contact":[{"telecom":[{"system":"url","value":"http://www.hl7.org/Special/committees/dss"}]}],"copyright":"https://creativecommons.org/licenses/by-nc-sa/4.0/","description":"This example uses the StatisticModelIncludeIf extension to represent the model characteristic of Welch's 2-sample t-test if the data is consistent with a normal distribution (based on Shapiro-Wilk test with p-value >= 0.05) and a Wilcoxon Mann-Whitney test if not.","extension":[{"url":"http://hl7.org/fhir/StructureDefinition/structuredefinition-wg","valueCode":"cds"}],"id":"example-statistic-model-include-if","identifier":[{"assigner":{"display":"Computable Publishing LLC"},"system":"urn:ietf:rfc:3986","type":{"text":"FEvIR Object Identifier"},"value":"https://fevir.net/FOI/346428"}],"meta":{"lastUpdated":"2025-03-10T14:59:32.227Z","profile":["http://hl7.org/fhir/uv/ebm/StructureDefinition/statistic-model"],"versionId":"9"},"publisher":"HL7 International / Clinical Decision Support","resourceType":"Evidence","statistic":[{"modelCharacteristic":[{"code":{"text":"Welch's 2-sample t-test"},"extension":[{"extension":[{"url":"attribute","valueCodeableConcept":{"text":"data distribution"}},{"url":"value","valueCodeableConcept":{"text":"normal distribution (Shapiro-Wilk test with p-value >= 0.05)"}}],"url":"http://hl7.org/fhir/StructureDefinition/statistic-model-include-if"}],"intended":true},{"code":{"text":"Wilcoxon Mann-Whitney test"},"extension":[{"extension":[{"url":"attribute","valueCodeableConcept":{"text":"data distribution"}},{"url":"value","valueCodeableConcept":{"text":"not consistent with normal distribution (Shapiro-Wilk test with p-value < 0.05)"}}],"url":"http://hl7.org/fhir/StructureDefinition/statistic-model-include-if"}],"intended":true}],"statisticType":{"coding":[{"code":"STATO:0000457","display":"difference in means","system":"https://fevir.net/sevco"}]}}],"status":"active","studyDesign":[{"coding":[{"code":"SEVCO:01003","display":"randomized assignment","system":"https://fevir.net/sevco"}]}],"title":"Example of statistical analysis plan with different statistical test if non-normal distribution","url":"http://hl7.org/fhir/Evidence/example-statistic-model-include-if","variableDefinition":[{"description":"Adults with hypertension","variableRole":"population"},{"description":"Reversitol vs. Placebo","variableRole":"exposure"},{"description":"Change in systolic blood pressure from baseline to 3 months","variableRole":"outcome"}]}