{"category":[{"coding":[{"code":"DRG","display":"Drug Interaction Alert","system":"http://terminology.hl7.org/CodeSystem/v3-ActCode"}]}],"code":{"coding":[{"code":"DRG","display":"Drug Interaction Alert","system":"http://terminology.hl7.org/CodeSystem/v3-ActCode"}]},"detail":"Risk of internal bleeding.  Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.","id":"ddi","identifiedDateTime":"2014-01-05","implicated":[{"display":"500 mg Acetaminophen tablet 1/day, PRN since 2010","reference":"MedicationStatement/example001"},{"display":"Warfarin 1 MG TAB prescribed Jan. 15, 2015","reference":"MedicationRequest/medrx0331"}],"mitigation":[{"action":{"coding":[{"code":"13","display":"Stopped Concurrent Therapy","system":"http://terminology.hl7.org/CodeSystem/v3-ActCode"}],"text":"Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring"},"author":{"display":"Dr. Adam Careful","reference":"Practitioner/example"},"date":"2014-01-05"}],"resourceType":"DetectedIssue","severity":{"coding":[{"code":"high","display":"High","system":"http://hl7.org/fhir/detectedissue-severity"}]},"status":"final","subject":{"reference":"Device/example"},"text":{"div":"<div xmlns=\"http://www.w3.org/1999/xhtml\">\n      <p><b>Severity: High</b> - Risk of internal bleeding</p>\n      <p>Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.</p>\n      <ul>\n        <li><a href=\"MedicationStatement/tylenol\">500 mg Acetaminophen tablet 1/day, PRN since 2010</a></li>\n        <li><a href=\"MedicationRequest/warfarin\">Warfarin 1 MG TAB prescribed Jan. 5, 2014</a></li>\n      </ul>\n      <p>Mitigation: Jan 5, 2014 by Dr. Adam Careful: </p>\n      <p>Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring</p>\n    </div>","status":"generated"}}